TreeWAS – Variant ID: rs2823962

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.045	0.955	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.044	0.956	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.043	0.957	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.043	0.957	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.041	0.959	0.000
T43.2 Other and unspecified antidepressants	0.041	0.959	0.000
T42.1 Iminostilbenes	0.041	0.959	0.000
T42.4 Benzodiazepines	0.041	0.959	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.039	0.961	0.000
T42.0 Hydantoin derivatives	0.038	0.961	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.037	0.963	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.037	0.963	0.000
T43.6 Psychostimulants with abuse potential	0.036	0.964	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.036	0.964	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.035	0.965	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.035	0.965	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.035	0.965	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.035	0.965	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.034	0.966	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.034	0.966	0.000
T42.3 Barbiturates	0.033	0.966	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.033	0.967	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.032	0.968	0.000
T42.2 Succinimides and oxazolidinediones	0.032	0.968	0.000
A04.7 Enterocolitis due to Clostridium difficile	0.000	0.968	0.032
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.032	0.968	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.032	0.968	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.031	0.968	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.031	0.968	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.031	0.968	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.031	0.968	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.031	0.968	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.031	0.968	0.000
T44.0 Anticholinesterase agents	0.031	0.968	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.031	0.969	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.031	0.969	0.000
T43.9 Psychotropic drug, unspecified	0.031	0.969	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.031	0.969	0.000
T45.2 Vitamins, not elsewhere classified	0.031	0.969	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.030	0.970	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.029	0.971	0.000
T38.0 Glucocorticoids and synthetic analogues	0.028	0.972	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.027	0.972	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.027	0.972	0.000
T36 Poisoning by systemic antibiotics	0.027	0.972	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.027	0.973	0.000
T47.0 Histamine H(2)-receptor antagonists	0.027	0.973	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.027	0.973	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.027	0.973	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.027	0.973	0.000
T45.8 Other primarily systemic and haematological agents	0.027	0.973	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.027	0.973	0.000
T45.6 Fibrinolysis-affecting drugs	0.027	0.973	0.000
T45.4 Iron and its compounds	0.027	0.973	0.000
T45.3 Enzymes, not elsewhere classified	0.027	0.973	0.000
T38.1 Thyroid hormones and substitutes	0.027	0.973	0.000
T47.6 Antidiarrhoeal drugs	0.027	0.973	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.026	0.974	0.000
T45.5 Anticoagulants	0.026	0.974	0.000
T48.5 Anti-common-cold drugs	0.025	0.974	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.025	0.975	0.000
T38.9 Other and unspecified hormone antagonists	0.025	0.975	0.000
T38.7 Androgens and anabolic congeners	0.025	0.975	0.000
T38.5 Other oestrogens and progestogens	0.025	0.975	0.000
T38.4 Oral contraceptives	0.025	0.975	0.000
T38.2 Antithyroid drugs	0.025	0.975	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.025	0.975	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.025	0.975	0.000
T47.7 Emetics	0.025	0.975	0.000
T47.5 Digestants	0.025	0.975	0.000
T47.3 Saline and osmotic laxatives	0.025	0.975	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.024	0.976	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.024	0.976	0.000
T46.7 Peripheral vasodilators	0.024	0.976	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.024	0.976	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.024	0.976	0.000
T47.2 Stimulant laxatives	0.024	0.976	0.000
T46.1 Calcium-channel blockers	0.024	0.976	0.000
T47.4 Other laxatives	0.024	0.976	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.023	0.977	0.000
T48.4 Expectorants	0.023	0.977	0.000
T48.3 Antitussives	0.023	0.977	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.023	0.977	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.023	0.977	0.000
T48.0 Oxytocic drugs	0.023	0.977	0.000
T45.0 Antiallergic and antiemetic drugs	0.023	0.977	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.022	0.977	0.000
T49.9 Topical agent, unspecified	0.022	0.977	0.000
T49.8 Other topical agents	0.022	0.977	0.000
T49.7 Dental drugs, topically applied	0.022	0.977	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.022	0.977	0.000
T49.5 Ophthalmological drugs and preparations	0.022	0.977	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.022	0.977	0.000
T49.3 Emollients, demulcents and protectants	0.022	0.977	0.000
T49.2 Local astringents and local detergents	0.022	0.977	0.000
T49.1 Antipruritics	0.022	0.977	0.000
T41.5 Therapeutic gases	0.022	0.977	0.000
T41.4 Anaesthetic, unspecified	0.022	0.977	0.000
T41.3 Local anaesthetics	0.022	0.977	0.000
T41.2 Other and unspecified general anaesthetics	0.022	0.977	0.000
T41.1 Intravenous anaesthetics	0.022	0.977	0.000
T41.0 Inhaled anaesthetics	0.022	0.977	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.022	0.978	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.021	0.979	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.020	0.980	0.000
T37.5 Antiviral drugs	0.020	0.980	0.000
T37.4 Anthelminthics	0.020	0.980	0.000
T37.3 Other antiprotozoal drugs	0.020	0.980	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.020	0.980	0.000
T37.1 Antimycobacterial drugs	0.020	0.980	0.000
T37.0 Sulphonamides	0.020	0.980	0.000
T36.9 Systemic antibiotic, unspecified	0.020	0.980	0.000
T36.8 Other systemic antibiotics	0.020	0.980	0.000
T36.7 Antifungal antibiotics, systemically used	0.020	0.980	0.000
T36.6 Rifamycins	0.020	0.980	0.000
T36.5 Aminoglycosides	0.020	0.980	0.000
T36.4 Tetracyclines	0.020	0.980	0.000
T36.3 Macrolides	0.020	0.980	0.000
T36.2 Chloramphenicol group	0.020	0.980	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.020	0.980	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.017	0.983	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.017	0.983	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.016	0.983	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.017	0.983	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.016	0.984	0.000
T36.0 Penicillins	0.016	0.984	0.000
T50.7 Analeptics and opioid receptor antagonists	0.016	0.984	0.000
T50.5 Appetite depressants	0.016	0.984	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.016	0.984	0.000
T50.1 Loop [high-ceiling] diuretics	0.016	0.984	0.000
T50.0 Mineralocorticoids and their antagonists	0.016	0.984	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.016	0.984	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.016	0.984	0.000
T50.4 Drugs affecting uric acid metabolism	0.015	0.985	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.015	0.985	0.000
T50.8 Diagnostic agents	0.015	0.985	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.014	0.986	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.014	0.986	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.014	0.986	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.013	0.987	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.012	0.988	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.012	0.988	0.000
T40.1 Heroin	0.011	0.988	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.011	0.989	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.011	0.989	0.000
T85.2 Mechanical complication of intraocular lens	0.011	0.989	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.010	0.989	0.000
T40.8 Lysergide [LSD]	0.010	0.989	0.000
T40.7 Cannabis (derivatives)	0.010	0.989	0.000
T40.3 Methadone	0.010	0.989	0.000
T40.0 Opium	0.010	0.989	0.000
T40.5 Cocaine	0.010	0.990	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.010	0.990	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.010	0.990	0.000
T39.4 Antirheumatics, not elsewhere classified	0.010	0.990	0.000
T39.2 Pyrazolone derivatives	0.010	0.990	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.009	0.991	0.000
C67.6 Ureteric orifice	0.009	0.991	0.000
T40.6 Other and unspecified narcotics	0.008	0.992	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.008	0.992	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.007	0.992	0.000
F06.7 Mild cognitive disorder	0.007	0.993	0.000
K13.0 Diseases of lips	0.000	0.993	0.007
C67.2 Lateral wall of bladder	0.007	0.993	0.000
C67 Malignant neoplasm of bladder	0.007	0.993	0.000
E11.4 With neurological complications	0.000	0.993	0.007
H61.0 Perichondritis of external ear	0.000	0.994	0.006
T40.2 Other opioids	0.006	0.994	0.000
C67.0 Trigone of bladder	0.006	0.994	0.000
K50.9 Crohn's disease, unspecified	0.000	0.994	0.006
T39.0 Salicylates	0.006	0.994	0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.000	0.994	0.006
T40.4 Other synthetic narcotics	0.005	0.994	0.000
C67.8 Overlapping lesion of bladder	0.005	0.994	0.000
C67.4 Posterior wall of bladder	0.006	0.994	0.000
I87.1 Compression of vein	0.000	0.995	0.005
C67.7 Urachus	0.005	0.995	0.000
C71.9 Brain, unspecified	0.000	0.995	0.005
C67.3 Anterior wall of bladder	0.005	0.995	0.000
C67.9 Bladder, unspecified	0.005	0.995	0.000
C67.1 Dome of bladder	0.005	0.995	0.000
D52.9 Folate deficiency anaemia, unspecified	0.000	0.995	0.005
G43.9 Migraine, unspecified	0.000	0.995	0.005
T39.1 4-Aminophenol derivatives	0.005	0.995	0.000
H02.4 Ptosis of eyelid	0.000	0.995	0.005
C67.5 Bladder neck	0.004	0.996	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.996	0.004
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.004	0.996	0.000
N90.4 Leukoplakia of vulva	0.000	0.996	0.004
C73 Malignant neoplasm of thyroid gland	0.004	0.996	0.000
H61.1 Non-infective disorders of pinna	0.000	0.996	0.004
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.003	0.996	0.000
K70.1 Alcoholic hepatitis	0.000	0.996	0.004
I49.0 Ventricular fibrillation and flutter	0.004	0.996	0.000
S00.1 Contusion of eyelid and periocular area	0.004	0.996	0.000
C71.2 Temporal lobe	0.000	0.997	0.003
E23.2 Diabetes insipidus	0.000	0.997	0.003
I87.8 Other specified disorders of veins	0.000	0.997	0.003
O20.9 Haemorrhage in early pregnancy, unspecified	0.003	0.997	0.000
H61 Other disorders of external ear	0.000	0.997	0.003
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.003	0.997	0.000
D12.7 Rectosigmoid junction	0.000	0.997	0.003
F06.3 Organic mood [affective] disorders	0.003	0.997	0.000
J30.3 Other allergic rhinitis	0.003	0.997	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.003	0.997	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.003	0.997	0.000
F06.5 Organic dissociative disorder	0.003	0.997	0.000
F06.4 Organic anxiety disorder	0.003	0.997	0.000
F06.1 Organic catatonic disorder	0.003	0.997	0.000
F06.0 Organic hallucinosis	0.003	0.997	0.000
G43.1 Migraine with aura [classical migraine]	0.000	0.997	0.003
G43 Migraine	0.000	0.997	0.003
F06.2 Organic delusional [schizophrenia-like] disorder	0.003	0.997	0.000
A04 Other bacterial intestinal infections	0.000	0.997	0.003
H61.8 Other specified disorders of external ear	0.000	0.997	0.003
H69.9 Eustachian tube disorder, unspecified	0.000	0.997	0.003
F10.4 Withdrawal state with delirium	0.003	0.997	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.003	0.997	0.000
C71 Malignant neoplasm of brain	0.000	0.997	0.003
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.997	0.003
I87 Other disorders of veins	0.000	0.997	0.003
Z11.0 Special screening examination for intestinal infectious diseases	0.003	0.997	0.000
E23.0 Hypopituitarism	0.000	0.997	0.003
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.997	0.003
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.003	0.997	0.000
G43.3 Complicated migraine	0.000	0.997	0.002
G43.2 Status migrainosus	0.000	0.997	0.002
G43.8 Other migraine	0.000	0.997	0.002
G43.0 Migraine without aura [common migraine]	0.000	0.997	0.002
M89.06 Algoneurodystrophy (Lower leg)	0.002	0.998	0.000
A04.6 Enteritis due to Yersinia enterocolitica	0.000	0.998	0.002
A04.3 Enterohaemorrhagic Escherichia coli infection	0.000	0.998	0.002
A04.2 Enteroinvasive Escherichia coli infection	0.000	0.998	0.002
A04.1 Enterotoxigenic Escherichia coli infection	0.000	0.998	0.002
A04.0 Enteropathogenic Escherichia coli infection	0.000	0.998	0.002
Q76.0 Spina bifida occulta	0.002	0.998	0.000
A87.9 Viral meningitis, unspecified	0.002	0.998	0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.002	0.998	0.000
D52 Folate deficiency anaemia	0.000	0.998	0.002
A04.9 Bacterial intestinal infection, unspecified	0.000	0.998	0.002
K70.0 Alcoholic fatty liver	0.002	0.998	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.002	0.998	0.000
D50.8 Other iron deficiency anaemias	0.000	0.998	0.002
F20.0 Paranoid schizophrenia	0.002	0.998	0.000
F00 Dementia in Alzheimer's disease	0.000	0.998	0.002
C71.6 Cerebellum	0.000	0.998	0.002
C71.5 Cerebral ventricle	0.000	0.998	0.002
S20.8 Superficial injuries of other and unspecified parts of thorax	0.000	0.998	0.002
I87.0 Postphlebitic syndrome	0.000	0.998	0.002
C77.3 Axillary and upper limb lymph nodes	0.002	0.998	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.002	0.998	0.000
C71.4 Occipital lobe	0.000	0.998	0.002
D28.0 Vulva	0.002	0.998	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.998	0.002
E23 Hypofunction and other disorders of pituitary gland	0.000	0.998	0.002
H53.2 Diplopia	0.000	0.998	0.002
C71.7 Brain stem	0.000	0.998	0.002
A04.4 Other intestinal Escherichia coli infections	0.000	0.998	0.002
Z35.5 Supervision of elderly primigravida	0.002	0.998	0.000
C21.0 Anus, unspecified	0.002	0.998	0.000
E21.3 Hyperparathyroidism, unspecified	0.002	0.998	0.000
H20.8 Other iridocyclitis	0.002	0.998	0.000
C71.1 Frontal lobe	0.000	0.998	0.002
C71.3 Parietal lobe	0.000	0.998	0.002
D52.8 Other folate deficiency anaemias	0.000	0.998	0.002
D52.1 Drug-induced folate deficiency anaemia	0.000	0.998	0.002
D52.0 Dietary folate deficiency anaemia	0.000	0.998	0.002
I87.9 Disorder of vein, unspecified	0.000	0.998	0.002
M77.91 Enthesopathy, unspecified (Shoulder region)	0.000	0.998	0.002
C71.8 Overlapping lesion of brain	0.000	0.998	0.002
H61.3 Acquired stenosis of external ear canal	0.000	0.998	0.002
Q23.1 Congenital insufficiency of aortic valve	0.000	0.998	0.002
B35.3 Tinea pedis	0.000	0.998	0.002
M70.46 Prepatellar bursitis-Lower Leg	0.002	0.998	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.000	0.998	0.002
Z35.9 Supervision of high-risk pregnancy, unspecified	0.002	0.998	0.000
R40.0 Somnolence	0.000	0.998	0.002
C85.1 B-cell lymphoma, unspecified	0.000	0.998	0.002
G63.2 Diabetic polyneuropathy	0.000	0.998	0.002
M89.0 Algoneurodystrophy	0.002	0.998	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.002	0.998	0.000
D86.9 Sarcoidosis, unspecified	0.002	0.998	0.000
H20.9 Iridocyclitis, unspecified	0.002	0.998	0.000
H61.9 Disorder of external ear, unspecified	0.000	0.998	0.002
Q28.2 Arteriovenous malformation of cerebral vessels	0.000	0.998	0.002
D68.8 Other specified coagulation defects	0.000	0.998	0.002
E24.9 Cushing's syndrome, unspecified	0.000	0.998	0.002
F02.0 Dementia in Pick's disease	0.000	0.998	0.002
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.998	0.002
E23.1 Drug-induced hypopituitarism	0.000	0.998	0.002
T63.4 Venom of other arthropods	0.000	0.998	0.002
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.002	0.998	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.000	0.998	0.002
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.998	0.002
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.998	0.002
M89.07 Algoneurodystrophy (Ankle and foot)	0.002	0.998	0.000
C71.0 Cerebrum, except lobes and ventricles	0.000	0.998	0.002
S81.0 Open wound of knee	0.002	0.998	0.000
R03.1 Nonspecific low blood-pressure reading	0.000	0.998	0.002
A87.2 Lymphocytic choriomeningitis	0.002	0.998	0.000
D86.8 Sarcoidosis of other and combined sites	0.002	0.998	0.000
F02 Dementia in other diseases classified elsewhere	0.000	0.998	0.002
J30.0 Vasomotor rhinitis	0.002	0.998	0.000
M89.88 Other specified disorders of bone (Other)	0.002	0.998	0.000
A04.5 Campylobacter enteritis	0.000	0.998	0.002
Q76.5 Cervical rib	0.002	0.998	0.000
D40.0 Prostate	0.002	0.998	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.000	0.998	0.002
G31.2 Degeneration of nervous system due to alcohol	0.000	0.998	0.002
K50.1 Crohn's disease of large intestine	0.000	0.998	0.002
F02.8 Dementia in other specified diseases classified elsewhere	0.000	0.998	0.002
C09.9 Tonsil, unspecified	0.002	0.998	0.000
A87 Viral meningitis	0.002	0.998	0.000
F02.3 Dementia in Parkinson's disease	0.000	0.998	0.002
M89.03 Algoneurodystrophy (Forearm)	0.002	0.998	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.998	0.002
M89.08 Algoneurodystrophy (Other)	0.001	0.998	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.001	0.998	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.001	0.998	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.001	0.998	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.002	0.998	0.000
Z51.5 Palliative care	0.002	0.998	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.002	0.998	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.002	0.998	0.000
L73.9 Follicular disorder, unspecified	0.002	0.998	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.002	0.998	0.000
G71.0 Muscular dystrophy	0.000	0.998	0.002
Q76.9 Congenital malformation of bony thorax, unspecified	0.001	0.998	0.000
Q76.8 Other congenital malformations of bony thorax	0.001	0.998	0.000
Q76.7 Congenital malformation of sternum	0.001	0.998	0.000
Q76.6 Other congenital malformations of ribs	0.001	0.998	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.001	0.998	0.000
Q76.2 Congenital spondylolisthesis	0.001	0.998	0.000
J30 Vasomotor and allergic rhinitis	0.002	0.998	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.002	0.998	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.002	0.998	0.000
K50 Crohn's disease [regional enteritis]	0.000	0.998	0.002
G31.0 Circumscribed brain atrophy	0.000	0.998	0.002
Q43.0 Meckel's diverticulum	0.000	0.998	0.002
E23.6 Other disorders of pituitary gland	0.000	0.998	0.001
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.000	0.998	0.001
F02.2 Dementia in Huntington's disease	0.000	0.998	0.001
F02.1 Dementia in Creutzfeldt-Jakob disease	0.000	0.998	0.001
H69 Other disorders of Eustachian tube	0.000	0.998	0.001
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns	0.001	0.998	0.000
B35.1 Tinea unguium	0.000	0.998	0.001
C48.2 Peritoneum, unspecified	0.000	0.998	0.001
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.001	0.999	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.001	0.999	0.000
A87.8 Other viral meningitis	0.001	0.999	0.000
A87.1 Adenoviral meningitis	0.001	0.999	0.000
A87.0 Enteroviral meningitis	0.001	0.999	0.000
C21.1 Anal canal	0.001	0.999	0.000
G31.8 Other specified degenerative diseases of nervous system	0.000	0.999	0.001
Q82.5 Congenital nonneoplastic naevus	0.001	0.999	0.000
X63.0 Home	0.001	0.999	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.999	0.001
Q76.1 Klippel-Feil syndrome	0.001	0.999	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.999	0.001
H20 Iridocyclitis	0.001	0.999	0.000
E24.0 Pituitary-dependent Cushing's disease	0.000	0.999	0.001
H69.8 Other specified disorders of Eustachian tube	0.000	0.999	0.001
M89.8 Other specified disorders of bone	0.001	0.999	0.000
E24 Cushing's syndrome	0.000	0.999	0.001
I81 Portal vein thrombosis	0.001	0.999	0.000
K72.9 Hepatic failure, unspecified	0.000	0.999	0.001
Z35 Supervision of high-risk pregnancy	0.001	0.999	0.000
E23.7 Disorder of pituitary gland, unspecified	0.000	0.999	0.001
E24.2 Drug-induced Cushing's syndrome	0.000	0.999	0.001
J94.8 Other specified pleural conditions	0.001	0.999	0.000
O23.5 Infections of the genital tract in pregnancy	0.001	0.999	0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.000	0.999	0.001
C75 Malignant neoplasm of other endocrine glands and related structures	0.001	0.999	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.999	0.001
Z43.1 Attention to gastrostomy	0.001	0.999	0.000
S92.50 Fracture of other toe (closed)	0.001	0.999	0.000
M19.1 Posttraumatic arthrosis of other joints	0.000	0.999	0.001
Q28.3 Other malformations of cerebral vessels	0.000	0.999	0.001
Z12.0 Special screening examination for neoplasm of stomach	0.000	0.999	0.001
Q28 Other congenital malformations of circulatory system	0.000	0.999	0.001
S72.80 Fractures of other parts of femur (closed)	0.001	0.999	0.000
L70.9 Acne, unspecified	0.000	0.999	0.001
Q28.0 Arteriovenous malformation of precerebral vessels	0.000	0.999	0.001
B35 Dermatophytosis	0.000	0.999	0.001
M89.83 Other specified disorders of bone (Forearm)	0.001	0.999	0.000
H26.8 Other specified cataract	0.000	0.999	0.001
H69.0 Patulous Eustachian tube	0.000	0.999	0.001
J30.2 Other seasonal allergic rhinitis	0.001	0.999	0.000
N18.4 Chronic kidney disease, stage 4	0.001	0.999	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.000	0.999	0.001
M25.46 Effusion of joint (Lower leg)	0.001	0.999	0.000
G71.1 Myotonic disorders	0.000	0.999	0.001
Q24.8 Other specified congenital malformations of heart	0.000	0.999	0.001
M89.04 Algoneurodystrophy (Hand)	0.001	0.999	0.000
M89.84 Other specified disorders of bone (Hand)	0.001	0.999	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.001	0.999	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.001	0.999	0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent	0.001	0.999	0.000
C75.1 Pituitary gland	0.001	0.999	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.001	0.999	0.000
E24.8 Other Cushing's syndrome	0.000	0.999	0.001
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.999	0.001
E24.3 Ectopic ACTH syndrome	0.000	0.999	0.001
E24.1 Nelson's syndrome	0.000	0.999	0.001
H02.5 Other disorders affecting eyelid function	0.000	0.999	0.001
H20.2 Lens-induced iridocyclitis	0.001	0.999	0.000
J21.9 Acute bronchiolitis, unspecified	0.000	0.999	0.001
O23.4 Unspecified infection of urinary tract in pregnancy	0.001	0.999	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.000	0.999	0.001
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.001	0.999	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.001	0.999	0.000
G95.1 Vascular myelopathies	0.000	0.999	0.001
Q83.1 Accessory breast	0.001	0.999	0.000
Z35.7 Supervision of high-risk pregnancy due to social problems	0.001	0.999	0.000
Z35.6 Supervision of very young primigravida	0.001	0.999	0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.001	0.999	0.000
C74 Malignant neoplasm of adrenal gland	0.001	0.999	0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.001	0.999	0.000
M54.47 Lumbago with sciatica (Lumbosacral region)	0.000	0.999	0.001
C75.9 Endocrine gland, unspecified	0.001	0.999	0.000
C75.8 Pluriglandular involvement, unspecified	0.001	0.999	0.000
C75.5 Aortic body and other paraganglia	0.001	0.999	0.000
C75.4 Carotid body	0.001	0.999	0.000
C75.3 Pineal gland	0.001	0.999	0.000
C75.2 Craniopharyngeal duct	0.001	0.999	0.000
E21.0 Primary hyperparathyroidism	0.001	0.999	0.000
J30.1 Allergic rhinitis due to pollen	0.001	0.999	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.999	0.001
Z35.8 Supervision of other high-risk pregnancies	0.001	0.999	0.000
C21 Malignant neoplasm of anus and anal canal	0.001	0.999	0.000
F03 Unspecified dementia	0.000	0.999	0.001
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)	0.000	0.999	0.001
M19.18 Post-traumatic arthrosis of other joints (Other)	0.000	0.999	0.001
M19.16 Post-traumatic arthrosis of other joints-Lower leg	0.000	0.999	0.001
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)	0.000	0.999	0.001
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)	0.000	0.999	0.001
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.000	0.999	0.001
Q28.9 Congenital malformation of circulatory system, unspecified	0.000	0.999	0.001
Q28.8 Other specified congenital malformations of circulatory system	0.000	0.999	0.001
Q28.1 Other malformations of precerebral vessels	0.000	0.999	0.001
Q60.2 Renal agenesis, unspecified	0.001	0.999	0.000
S81.8 Open wound of other parts of lower leg	0.000	0.999	0.001
F01 Vascular dementia	0.000	0.999	0.001
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.001	0.999	0.000
B35.8 Other dermatophytoses	0.000	0.999	0.001
B35.5 Tinea imbricata	0.000	0.999	0.001
B35.2 Tinea manuum	0.000	0.999	0.001
B35.0 Tinea barbae and tinea capitis	0.000	0.999	0.001
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.001	0.999	0.000
H20.1 Chronic iridocyclitis	0.001	0.999	0.000
K55.9 Vascular disorder of intestine, unspecified	0.001	0.999	0.000
R25.1 Tremor, unspecified	0.000	0.999	0.001
E22 Hyperfunction of pituitary gland	0.001	0.999	0.000
F20 Schizophrenia	0.001	0.999	0.000
M79.67 Pain in limb (Ankle and foot)	0.001	0.999	0.000
B35.6 Tinea cruris	0.000	0.999	0.001
B35.4 Tinea corporis	0.000	0.999	0.001
C75.0 Parathyroid gland	0.001	0.999	0.000
O23.0 Infections of kidney in pregnancy	0.001	0.999	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.001	0.999	0.000
C74.1 Medulla of adrenal gland	0.001	0.999	0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.001	0.999	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.001	0.999	0.000
F09 Unspecified organic or symptomatic mental disorder	0.000	0.999	0.001
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.000	0.999	0.001
B35.9 Dermatophytosis, unspecified	0.000	0.999	0.001
C21.2 Cloacogenic zone	0.001	0.999	0.000
C74.0 Cortex of adrenal gland	0.001	0.999	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.001	0.999	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.999	0.001
G25.0 Essential tremor	0.000	0.999	0.001
H20.0 Acute and subacute iridocyclitis	0.001	0.999	0.000
L98.0 Pyogenic granuloma	0.001	0.999	0.000
M19.12 Post-traumatic arthrosis of other joints (Upper arm)	0.000	0.999	0.001
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.001	0.999	0.000
F01.9 Vascular dementia, unspecified	0.000	0.999	0.001
F01.1 Multi-infarct dementia	0.000	0.999	0.001
K72.1 Chronic hepatic failure	0.000	0.999	0.001
K72.0 Acute and subacute hepatic failure	0.000	0.999	0.001
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.000	0.999	0.001
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.001	0.999	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.001	0.999	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.001	0.999	0.000
E22.8 Other hyperfunction of pituitary gland	0.001	0.999	0.000
F01.8 Other vascular dementia	0.000	0.999	0.001
F01.3 Mixed cortical and subcortical vascular dementia	0.000	0.999	0.001
F01.2 Subcortical vascular dementia	0.000	0.999	0.001
F01.0 Vascular dementia of acute onset	0.000	0.999	0.001
F20.8 Other schizophrenia	0.001	0.999	0.000
F20.6 Simple schizophrenia	0.001	0.999	0.000
F20.4 Postschizophrenic depression	0.001	0.999	0.000
F20.3 Undifferentiated schizophrenia	0.001	0.999	0.000
F20.2 Catatonic schizophrenia	0.001	0.999	0.000
F20.1 Hebephrenic schizophrenia	0.001	0.999	0.000
H93.9 Disorder of ear, unspecified	0.000	0.999	0.001
O23 Infections of genito-urinary tract in pregnancy	0.001	0.999	0.000
M85.47 Solitary bone cyst (Ankle and foot)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations