TreeWAS – Variant ID: rs2826340

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D23 Other benign neoplasms of skin	0.000	0.866	0.134
D23.6 Skin of upper limb, including shoulder	0.000	0.867	0.133
D23.7 Skin of lower limb, including hip	0.000	0.869	0.131
D23.2 Skin of ear and external auricular canal	0.000	0.878	0.122
D23.9 Skin, unspecified	0.000	0.880	0.120
D23.0 Skin of lip	0.000	0.889	0.111
D23.3 Skin of other and unspecified parts of face	0.000	0.894	0.106
D23.4 Skin of scalp and neck	0.000	0.895	0.105
D23.1 Skin of eyelid, including canthus	0.000	0.898	0.102
D23.5 Skin of trunk	0.000	0.973	0.027
K01.1 Impacted teeth	0.000	0.980	0.020
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.015	0.985	0.000
O46.9 Antepartum haemorrhage, unspecified	0.013	0.987	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.990	0.010
Y42.7 Androgens and anabolic congeners	0.010	0.990	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.010	0.990	0.000
Y42.5 Other oestrogens and progestogens	0.009	0.991	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.009	0.991	0.000
Y42.1 Thyroid hormones and substitutes	0.008	0.992	0.000
K59.8 Other specified functional intestinal disorders	0.008	0.992	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.007	0.993	0.000
R30.0 Dysuria	0.007	0.993	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.007	0.993	0.000
Y42.9 Other and unspecified hormone antagonists	0.007	0.993	0.000
Y42.4 Oral contraceptives	0.007	0.993	0.000
Y42.2 Antithyroid drugs	0.007	0.993	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.007	0.993	0.000
Z85.5 Personal history of malignant neoplasm of urinary tract	0.007	0.993	0.000
D47.1 Chronic myeloproliferative disease	0.007	0.993	0.000
Y44 Agents primarily affecting blood constituents	0.007	0.993	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.007	0.993	0.000
H15 Disorders of sclera	0.007	0.993	0.000
Y41.5 Antiviral drugs	0.006	0.993	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.006	0.994	0.000
Y41.1 Antimycobacterial drugs	0.006	0.994	0.000
K01 Embedded and impacted teeth	0.000	0.994	0.006
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.006	0.994	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.006	0.994	0.000
Y44.2 Anticoagulants	0.006	0.994	0.000
Y58 Bacterial vaccines	0.006	0.994	0.000
H15.1 Episcleritis	0.006	0.994	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.006	0.994	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.006	0.994	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.006	0.994	0.000
Y41.0 Sulphonamides	0.006	0.994	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.006	0.994	0.000
Y52 Agents primarily affecting the cardiovascular system	0.006	0.994	0.000
H18 Other disorders of cornea	0.006	0.994	0.000
Y59 Other and unspecified vaccines and biological substances	0.006	0.994	0.000
H21 Other disorders of iris and ciliary body	0.006	0.994	0.000
H15.8 Other disorders of sclera	0.006	0.994	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.006	0.994	0.000
Y52.1 Calcium-channel blockers	0.006	0.994	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.006	0.994	0.000
H16 Keratitis	0.006	0.994	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.005	0.994	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.005	0.994	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.006	0.994	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.005	0.994	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.005	0.994	0.000
Y58.0 BCG vaccine	0.005	0.995	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.005	0.995	0.000
Y41.4 Anthelminthics	0.005	0.995	0.000
Y41.3 Other antiprotozoal drugs	0.005	0.995	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.005	0.995	0.000
Y54.7 Agents affecting calcification	0.005	0.995	0.000
H40.0 Glaucoma suspect	0.000	0.995	0.005
Y46 Antiepileptics and anti-Parkinsonism drugs	0.005	0.995	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.005	0.995	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.005	0.995	0.000
Y47.1 Benzodiazepines	0.005	0.995	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.005	0.995	0.000
Y53.4 Other laxatives	0.005	0.995	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.995	0.005
H17 Corneal scars and opacities	0.005	0.995	0.000
H15.0 Scleritis	0.005	0.995	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
Y54.8 Agents affecting uric acid metabolism	0.005	0.995	0.000
H21.8 Other specified disorders of iris and ciliary body	0.005	0.995	0.000
H18.8 Other specified disorders of cornea	0.005	0.995	0.000
Y48 Anaesthetics and therapeutic gases	0.005	0.995	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.005	0.995	0.000
Y44.7 Plasma substitutes	0.005	0.995	0.000
Y44.6 Natural blood and blood products	0.005	0.995	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.005	0.995	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.005	0.995	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.005	0.995	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.005	0.995	0.000
Y56.9 Topical agent, unspecified	0.005	0.995	0.000
Y56.8 Other topical agents	0.005	0.995	0.000
Y56.7 Dental drugs, topically applied	0.005	0.995	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.005	0.995	0.000
Y56.5 Ophthalmological drugs and preparations	0.005	0.995	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.005	0.995	0.000
Y56.3 Emollients, demulcents and protectants	0.005	0.995	0.000
Y56.2 Local astringents and local detergents	0.005	0.995	0.000
Y56.1 Antipruritics	0.005	0.995	0.000
H18.4 Corneal degeneration	0.005	0.995	0.000
H18.2 Other corneal oedema	0.005	0.995	0.000
H15.9 Disorder of sclera, unspecified	0.005	0.995	0.000
Y86 Sequelae of other accidents	0.000	0.995	0.005
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.005	0.995	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.005	0.995	0.000
H20 Iridocyclitis	0.005	0.995	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.005	0.995	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.005	0.995	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.005	0.995	0.000
D47.4 Osteomyelofibrosis	0.005	0.995	0.000
Y44.5 Thrombolytic drugs	0.005	0.995	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.005	0.995	0.000
H21.4 Pupillary membranes	0.005	0.995	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.005	0.995	0.000
Y53.7 Emetics	0.005	0.995	0.000
Y53.6 Antidiarrhoeal drugs	0.005	0.995	0.000
Y53.5 Digestants	0.005	0.995	0.000
Y53.3 Saline and osmotic laxatives	0.005	0.995	0.000
Y53.2 Stimulant laxatives	0.005	0.995	0.000
Y53.0 Histamine H2-receptor antagonists	0.005	0.995	0.000
Y58.9 Other and unspecified bacterial vaccines	0.005	0.995	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.005	0.995	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.005	0.995	0.000
Y58.5 Diphtheria vaccine	0.005	0.995	0.000
Y58.4 Tetanus vaccine	0.005	0.995	0.000
Y58.3 Plague vaccine	0.005	0.995	0.000
Y58.2 Cholera vaccine	0.005	0.995	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.005	0.995	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.005	0.995	0.000
H18.9 Disorder of cornea, unspecified	0.005	0.995	0.000
Y40 Systemic antibiotics	0.005	0.995	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.004	0.995	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.004	0.995	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.004	0.995	0.000
Y47.4 Bromine compounds	0.004	0.995	0.000
Y47.3 Paraldehyde	0.004	0.995	0.000
Y47.2 Chloral derivatives	0.004	0.995	0.000
Y47.0 Barbiturates, not elsewhere classified	0.004	0.995	0.000
H16.2 Keratoconjunctivitis	0.005	0.995	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.004	0.995	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.004	0.995	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.005	0.995	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.005	0.995	0.000
Y59.3 Immunoglobulin	0.004	0.995	0.000
H18.3 Changes in corneal membranes	0.004	0.995	0.000
H16.8 Other keratitis	0.004	0.995	0.000
Y54.9 Mineral salts, not elsewhere classified	0.004	0.995	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.004	0.995	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.004	0.995	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.004	0.995	0.000
Y54.0 Mineralocorticoids	0.004	0.995	0.000
H71 Cholesteatoma of middle ear	0.000	0.995	0.005
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.004	0.995	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.004	0.995	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.004	0.995	0.000
Y52.7 Peripheral vasodilators	0.004	0.995	0.000
Y46.7 Anti-Parkinsonism drugs	0.004	0.996	0.000
Y57 Other and unspecified drugs and medicaments	0.004	0.996	0.000
H18.7 Other corneal deformities	0.004	0.996	0.000
H18.1 Bullous keratopathy	0.004	0.996	0.000
H18.0 Corneal pigmentations and deposits	0.004	0.996	0.000
H16.9 Keratitis, unspecified	0.004	0.996	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.004	0.996	0.000
Y54.4 Loop [high-ceiling] diuretics	0.004	0.996	0.000
Y59.9 Vaccine or biological substance, unspecified	0.004	0.996	0.000
Y59.8 Other specified vaccines and biological substances	0.004	0.996	0.000
Y59.2 Protozoal vaccines	0.004	0.996	0.000
Y59.1 Rickettsial vaccines	0.004	0.996	0.000
Y59.0 Viral vaccines	0.004	0.996	0.000
H18.6 Keratoconus	0.004	0.996	0.000
H20.0 Acute and subacute iridocyclitis	0.004	0.996	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.004	0.996	0.000
H21.2 Degeneration of iris and ciliary body	0.004	0.996	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.004	0.996	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.004	0.996	0.000
Y54.5 Other diuretics	0.004	0.996	0.000
T39.0 Salicylates	0.000	0.996	0.004
H21.9 Disorder of iris and ciliary body, unspecified	0.004	0.996	0.000
H16.4 Corneal neovascularisation	0.004	0.996	0.000
H16.3 Interstitial and deep keratitis	0.004	0.996	0.000
Y50.9 Central nervous system stimulant, unspecified	0.004	0.996	0.000
Y50.8 Other central nervous system stimulants	0.004	0.996	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.004	0.996	0.000
Y50.1 Opioid receptor antagonists	0.004	0.996	0.000
Y50.0 Analeptics	0.004	0.996	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.004	0.996	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.004	0.996	0.000
Y55.5 Anticommon cold drugs	0.004	0.996	0.000
Y55.4 Expectorants	0.004	0.996	0.000
Y55.3 Antitussives	0.004	0.996	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.004	0.996	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.004	0.996	0.000
Y55.0 Oxytocic drugs	0.004	0.996	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.004	0.996	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.004	0.996	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.004	0.996	0.000
T39.1 4-Aminophenol derivatives	0.000	0.996	0.004
Y52.3 Coronary vasodilators, not elsewhere classified	0.004	0.996	0.000
H16.0 Corneal ulcer	0.004	0.996	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.004	0.996	0.000
H17.8 Other corneal scars and opacities	0.004	0.996	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.004	0.996	0.000
Y46.6 Other and unspecified antiepileptics	0.004	0.996	0.000
Y49.5 Other antipsychotics and neuroleptics	0.004	0.996	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.004	0.996	0.000
Y46.8 Antispasticity drugs	0.004	0.996	0.000
Y46.5 Valproic acid	0.004	0.996	0.000
Y46.3 Deoxybarbiturates	0.004	0.996	0.000
Y46.1 Oxazolidinediones	0.004	0.996	0.000
Y46.0 Succinimides	0.004	0.996	0.000
H20.1 Chronic iridocyclitis	0.004	0.996	0.000
Y49.9 Psychotropic drug, unspecified	0.004	0.996	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
Y49.7 Psychostimulants with abuse potential	0.004	0.996	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.004	0.996	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.004	0.996	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.004	0.996	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.004	0.996	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.004	0.996	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.004	0.996	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.004	0.996	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.004	0.996	0.000
Y51.0 Anticholinesterase agents	0.004	0.996	0.000
H17.9 Corneal scar and opacity, unspecified	0.004	0.996	0.000
T39.4 Antirheumatics, not elsewhere classified	0.000	0.996	0.004
T39.2 Pyrazolone derivatives	0.000	0.996	0.004
Y48.3 Local anaesthetics	0.004	0.996	0.000
H17.1 Other central corneal opacity	0.004	0.996	0.000
H17.0 Adherent leukoma	0.004	0.996	0.000
O46.8 Other antepartum haemorrhage	0.004	0.996	0.000
I50.9 Heart failure, unspecified	0.004	0.996	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.996	0.004
K01.0 Embedded teeth	0.000	0.996	0.004
Y48.5 Therapeutic gases	0.004	0.996	0.000
Y48.1 Parenteral anaesthetics	0.004	0.996	0.000
Y48.0 Inhaled anaesthetics	0.004	0.996	0.000
Y40.0 Penicillins	0.004	0.996	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.004	0.996	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.004	0.996	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
Y46.2 Hydantoin derivatives	0.004	0.996	0.000
H20.2 Lens-induced iridocyclitis	0.004	0.996	0.000
Y46.4 Iminostilbenes	0.004	0.996	0.000
Y48.2 Other and unspecified general anaesthetics	0.004	0.996	0.000
Y49.2 Other and unspecified antidepressants	0.003	0.996	0.000
Y40.3 Macrolides	0.004	0.996	0.000
Y40.5 Aminoglycosides	0.003	0.996	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.996	0.003
Y40.7 Antifungal antibiotics, systemically used	0.003	0.996	0.000
Y40.6 Rifamycins	0.003	0.996	0.000
Y40.4 Tetracyclines	0.003	0.996	0.000
Y40.2 Chloramphenicol group	0.003	0.996	0.000
K59.3 Megacolon, not elsewhere classified	0.004	0.996	0.000
Y43 Primarily systemic agents	0.004	0.996	0.000
K86.1 Other chronic pancreatitis	0.004	0.996	0.000
H21.0 Hyphaema	0.003	0.996	0.000
Y57.9 Drug or medicament, unspecified	0.003	0.996	0.000
H20.9 Iridocyclitis, unspecified	0.003	0.997	0.000
Y43.0 Antiallergic and antiemetic drugs	0.003	0.997	0.000
Y57.7 Vitamins, not elsewhere classified	0.003	0.997	0.000
Y57.4 Pharmaceutical excipients	0.003	0.997	0.000
Y57.3 Alcohol deterrents	0.003	0.997	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.003	0.997	0.000
Y57.1 Lipotropic drugs	0.003	0.997	0.000
Y57.0 Appetite depressants [anorectics]	0.003	0.997	0.000
Y48.4 Anaesthetic, unspecified	0.003	0.997	0.000
J95.8 Other postprocedural respiratory disorders	0.003	0.997	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.003	0.997	0.000
Y57.6 Other diagnostic agents	0.003	0.997	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.997	0.000
I50 Heart failure	0.003	0.997	0.000
K59 Other functional intestinal disorders	0.003	0.997	0.000
R45.8 Other symptoms and signs involving emotional state	0.000	0.997	0.003
I50.0 Congestive heart failure	0.003	0.997	0.000
K72.0 Acute and subacute hepatic failure	0.003	0.997	0.000
I50.1 Left ventricular failure	0.003	0.997	0.000
O36.8 Maternal care for other specified foetal problems	0.003	0.997	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.003	0.997	0.000
Y40.8 Other systemic antibiotics	0.003	0.997	0.000
Y57.8 Other drugs and medicaments	0.003	0.997	0.000
T79.6 Traumatic ischaemia of muscle	0.003	0.997	0.000
C56 Malignant neoplasm of ovary	0.003	0.997	0.000
R30 Pain associated with micturition	0.003	0.997	0.000
K75.0 Abscess of liver	0.003	0.997	0.000
Y57.5 X-ray contrast media	0.003	0.997	0.000
R47.0 Dysphasia and aphasia	0.000	0.997	0.003
Y54.3 Benzothiadiazine derivatives	0.003	0.997	0.000
Y43.9 Primarily systemic agent, unspecified	0.003	0.997	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.003	0.997	0.000
Y43.6 Enzymes, not elsewhere classified	0.003	0.997	0.000
Y43.5 Acidifying and alkalising agents	0.003	0.997	0.000
Y43.2 Antineoplastic natural products	0.003	0.997	0.000
K59.4 Anal spasm	0.003	0.997	0.000
K59.1 Functional diarrhoea	0.003	0.997	0.000
D04.3 Skin of other and unspecified parts of face	0.003	0.997	0.000
H18.5 Hereditary corneal dystrophies	0.002	0.997	0.000
H20.8 Other iridocyclitis	0.002	0.997	0.000
G95.2 Cord compression, unspecified	0.003	0.997	0.000
Y43.4 Immunosuppressive agents	0.003	0.997	0.000
K59.2 Neurogenic bowel, not elsewhere classified	0.002	0.997	0.000
G11.9 Hereditary ataxia, unspecified	0.003	0.997	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
I15.1 Hypertension secondary to other renal disorders	0.002	0.997	0.000
G80.9 Infantile cerebral palsy, unspecified	0.002	0.998	0.000
D41.4 Bladder	0.002	0.998	0.000
D43.2 Brain, unspecified	0.002	0.998	0.000
R30.1 Vesical tenesmus	0.002	0.998	0.000
D47.2 Monoclonal gammopathy	0.002	0.998	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.002	0.998	0.000
R30.9 Painful micturition, unspecified	0.002	0.998	0.000
K66.8 Other specified disorders of peritoneum	0.002	0.998	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.002	0.998	0.000
O42.9 Premature rupture of membranes, unspecified	0.002	0.998	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.002	0.998	0.000
Y43.1 Antineoplastic antimetabolites	0.002	0.998	0.000
C16.9 Stomach, unspecified	0.000	0.998	0.002
Z90.6 Acquired absence of other parts of urinary tract	0.002	0.998	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.002	0.998	0.000
Y40.9 Systemic antibiotic, unspecified	0.001	0.998	0.001
O36 Maternal care for other known or suspected foetal problems	0.002	0.998	0.000
O75.8 Other specified complications of labour and delivery	0.002	0.998	0.000
R44.1 Visual hallucinations	0.002	0.998	0.000
K86 Other diseases of pancreas	0.002	0.998	0.000
H93.1 Tinnitus	0.002	0.998	0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.000	0.998	0.002
O36.1 Maternal care for other isoimmunisation	0.002	0.998	0.000
D45 Polycythaemia vera	0.002	0.998	0.000
D38.0 Larynx	0.002	0.998	0.000
K86.8 Other specified diseases of pancreas	0.002	0.998	0.000
T79.5 Traumatic anuria	0.002	0.998	0.000
O36.9 Maternal care for foetal problem, unspecified	0.002	0.998	0.000
G80.8 Other infantile cerebral palsy	0.002	0.998	0.000
S72.00 Fracture of neck of femur (closed)	0.000	0.998	0.002
K86.2 Cyst of pancreas	0.002	0.998	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.002	0.998	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.002	0.998	0.000
G80 Infantile cerebral palsy	0.002	0.998	0.000
D43.4 Spinal cord	0.002	0.998	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.002	0.998	0.000
R20.2 Paraesthesia of skin	0.000	0.998	0.002
K72 Hepatic failure, not elsewhere classified	0.002	0.998	0.000
T79.7 Traumatic subcutaneous emphysema	0.002	0.998	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.002	0.998	0.000
D10.3 Other and unspecified parts of mouth	0.000	0.998	0.002
D43.9 Central nervous system, unspecified	0.002	0.998	0.000
D43.7 Other parts of central nervous system	0.002	0.998	0.000
D43.3 Cranial nerves	0.002	0.998	0.000
D43.1 Brain, infratentorial	0.002	0.998	0.000
K59.9 Functional intestinal disorder, unspecified	0.002	0.998	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.002	0.998	0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.002	0.998	0.000
K86.3 Pseudocyst of pancreas	0.002	0.998	0.000
N85.9 Noninflammatory disorder of uterus, unspecified	0.002	0.998	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.002	0.998	0.000
G80.0 Spastic cerebral palsy	0.002	0.998	0.000
L05.0 Pilonidal cyst with abscess	0.000	0.998	0.002
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.002	0.998	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.000	0.998	0.002
D41.9 Urinary organ, unspecified	0.002	0.998	0.000
D41.7 Other urinary organs	0.002	0.998	0.000
D41.3 Urethra	0.002	0.998	0.000
D41.2 Ureter	0.002	0.998	0.000
D41.1 Renal pelvis	0.002	0.998	0.000
M21.6 Other acquired deformities of ankle and foot	0.002	0.998	0.000
C16.0 Cardia	0.000	0.998	0.002
D44.3 Pituitary gland	0.002	0.998	0.000
K72.9 Hepatic failure, unspecified	0.002	0.998	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.002	0.998	0.000
O36.4 Maternal care for intra-uterine death	0.002	0.998	0.000
O36.2 Maternal care for hydrops foetalis	0.002	0.998	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.002	0.998	0.000
O63.9 Long labour, unspecified	0.002	0.998	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.002	0.998	0.000
C18.0 Caecum	0.000	0.998	0.002
D03.5 Melanoma in situ of trunk	0.002	0.998	0.000
D40.1 Testis	0.002	0.998	0.000
O32.0 Maternal care for unstable lie	0.002	0.998	0.000
G80.1 Spastic diplegia	0.002	0.998	0.000
H40.8 Other glaucoma	0.000	0.998	0.002
M21.1 Varus deformity, not elsewhere classified	0.002	0.998	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.002	0.998	0.000
D40.9 Male genital organ, unspecified	0.001	0.998	0.000
D40.7 Other male genital organs	0.001	0.998	0.000
G80.4 Ataxic cerebral palsy	0.001	0.998	0.000
G80.3 Dyskinetic cerebral palsy	0.001	0.998	0.000
G80.2 Infantile hemiplegia	0.001	0.998	0.000
L98.0 Pyogenic granuloma	0.002	0.998	0.000
O75.0 Maternal distress during labour and delivery	0.002	0.998	0.000
R25.1 Tremor, unspecified	0.000	0.998	0.002
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.002	0.998	0.000
D38.6 Respiratory organ, unspecified	0.001	0.998	0.000
D38.5 Other respiratory organs	0.001	0.998	0.000
D38.4 Thymus	0.001	0.998	0.000
D38.3 Mediastinum	0.001	0.998	0.000
D38.2 Pleura	0.001	0.998	0.000
D40.0 Prostate	0.001	0.998	0.000
D44.1 Adrenal gland	0.001	0.998	0.000
T79.9 Unspecified early complication of trauma	0.001	0.998	0.000
T79.4 Traumatic shock	0.001	0.998	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.001	0.998	0.000
T79.1 Fat embolism (traumatic)	0.001	0.998	0.000
T79.0 Air embolism (traumatic)	0.001	0.998	0.000
D44.9 Endocrine gland, unspecified	0.001	0.998	0.000
D44.6 Carotid body	0.001	0.998	0.000
D44.5 Pineal gland	0.001	0.998	0.000
D44.2 Parathyroid gland	0.001	0.998	0.000
K72.1 Chronic hepatic failure	0.001	0.998	0.000
T79.8 Other early complications of trauma	0.001	0.998	0.000
Y45.5 4-Aminophenol derivatives	0.001	0.998	0.000
G11 Hereditary ataxia	0.002	0.998	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.000	0.998	0.001
D44.7 Aortic body and other paraganglia	0.001	0.998	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.001	0.998	0.000
O90 Complications of the puerperium, not elsewhere classified	0.002	0.998	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
D44.0 Thyroid gland	0.001	0.998	0.000
Y45.4 Antirheumatics	0.001	0.998	0.000
D37.1 Stomach	0.002	0.998	0.000
D42.9 Meninges, unspecified	0.001	0.998	0.000
D42.1 Spinal meninges	0.001	0.998	0.000
D42.0 Cerebral meninges	0.001	0.998	0.000
D43.0 Brain, supratentorial	0.001	0.998	0.000
I87.8 Other specified disorders of veins	0.002	0.998	0.000
C45.9 Mesothelioma, unspecified	0.002	0.998	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.001	0.998	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.001	0.998	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.001	0.998	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.001	0.998	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.001	0.998	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.001	0.998	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.001	0.998	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.001	0.998	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.001	0.998	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.001	0.998	0.000
D44.8 Pluriglandular involvement	0.001	0.998	0.000
O63.1 Prolonged second stage (of labour)	0.002	0.998	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.002	0.998	0.000
D44.4 Craniopharyngeal duct	0.001	0.998	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.001	0.998	0.000
N89.5 Stricture and atresia of vagina	0.001	0.998	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.001	0.998	0.000
D10.1 Tongue	0.000	0.999	0.001
G11.4 Hereditary spastic paraplegia	0.001	0.999	0.000
I15.9 Seconday hypertension, unspecified	0.001	0.999	0.000
O86.0 Infection of obstetric surgical wound	0.001	0.999	0.000
R01.0 Benign and innocent cardiac murmurs	0.001	0.999	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.001	0.999	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.001	0.999	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.001	0.999	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.001	0.999	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
D39.0 Uterus	0.001	0.999	0.000
M21.4 Flat foot [pes planus] (acquired)	0.001	0.999	0.000
M24.02 Loose body in joint (Upper arm)	0.000	0.999	0.001
D39.9 Female genital organ, unspecified	0.001	0.999	0.000
D39.7 Other female genital organs	0.001	0.999	0.000
D39.2 Placenta	0.001	0.999	0.000
O36.5 Maternal care for poor foetal growth	0.001	0.999	0.000
O90.1 Disruption of perineal obstetric wound	0.001	0.999	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.999	0.001
H58.8 Visual disturbances in diseases classified elsewhere	0.001	0.999	0.000
K75.4 Autoimmune hepatitis	0.001	0.999	0.000
O90.2 Haematoma of obstetric wound	0.001	0.999	0.000
W84.9 Unspecified place	0.001	0.999	0.000
C16 Malignant neoplasm of stomach	0.000	0.999	0.001
I15 Secondary hypertension	0.001	0.999	0.000
B02.3 Zoster ocular disease	0.001	0.999	0.000
G11.8 Other hereditary ataxias	0.001	0.999	0.000
G11.3 Cerebellar ataxia with defective DNA repair	0.001	0.999	0.000
G11.2 Late-onset cerebellar ataxia	0.001	0.999	0.000
G11.1 Early-onset cerebellar ataxia	0.001	0.999	0.000
G11.0 Congenital nonprogressive ataxia	0.001	0.999	0.000
N92.4 Excessive bleeding in the premenopausal period	0.000	0.999	0.001
O90.5 Postpartum thyroiditis	0.001	0.999	0.000
O90.4 Postpartum acute renal failure	0.001	0.999	0.000
O90.3 Cardiomyopathy in the puerperium	0.001	0.999	0.000
O90.0 Disruption of Caesarean section wound	0.001	0.999	0.000
V78.1 Passenger injured in nontraffic accident	0.001	0.999	0.000
C16.3 Pyloric antrum	0.000	0.999	0.001
H43.1 Vitreous haemorrhage	0.000	0.999	0.001
O90.9 Complication of the puerperium, unspecified	0.001	0.999	0.000
Y45.8 Other analgesics and antipyretics	0.001	0.999	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.001	0.999	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.001	0.999	0.000
M70.22 Olecranon bursitis-Upper arm	0.001	0.999	0.000
O86 Other puerperal infections	0.001	0.999	0.000
Y89 Sequelae of other external causes	0.000	0.999	0.001
Z88.5 Personal history of allergy to narcotic agent	0.001	0.999	0.000
Z88.1 Personal history of allergy to other antibiotic agents	0.001	0.999	0.000
C52 Malignant neoplasm of vagina	0.001	0.999	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.001	0.999	0.000
D10.0 Lip	0.000	0.999	0.001
D37.6 Liver, gallbladder and bile ducts	0.001	0.999	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.000	0.999	0.001
M05.9 Seropositive rheumatoid arthritis, unspecified	0.001	0.999	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations