TreeWAS – Variant ID: rs2832270

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H72.0 Central perforation of tympanic membrane	0.019	0.981	0.000
H72 Perforation of tympanic membrane	0.017	0.983	0.000
H65-H75 Diseases of middle ear and mastoid	0.017	0.983	0.000
H71 Cholesteatoma of middle ear	0.016	0.984	0.000
H70 Mastoiditis and related conditions	0.015	0.985	0.000
H74 Other disorders of middle ear and mastoid	0.014	0.986	0.000
H72.8 Other perforations of tympanic membrane	0.014	0.986	0.000
H70.1 Chronic mastoiditis	0.013	0.987	0.000
H74.0 Tympanosclerosis	0.013	0.987	0.000
H69 Other disorders of Eustachian tube	0.012	0.987	0.000
H73 Other disorders of tympanic membrane	0.012	0.988	0.000
H72.1 Attic perforation of tympanic membrane	0.012	0.988	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.012	0.988	0.000
H68 Eustachian salpingitis and obstruction	0.012	0.988	0.000
H67 Otitis media in diseases classified elsewhere	0.012	0.988	0.000
H70.9 Mastoiditis, unspecified	0.012	0.988	0.000
H66 Suppurative and unspecified otitis media	0.012	0.988	0.000
H72.2 Other marginal perforations of tympanic membrane	0.011	0.988	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.011	0.989	0.000
Chapter VIII Diseases of the ear and mastoid process	0.011	0.989	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.011	0.989	0.000
H70.8 Other mastoiditis and related conditions	0.011	0.989	0.000
H70.2 Petrositis	0.011	0.989	0.000
H70.0 Acute mastoiditis	0.011	0.989	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.011	0.989	0.000
H74.1 Adhesive middle ear disease	0.010	0.990	0.000
H69.9 Eustachian tube disorder, unspecified	0.010	0.990	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.010	0.990	0.000
H60-H62 Diseases of external ear	0.009	0.991	0.000
H35.8 Other specified retinal disorders	0.000	0.991	0.009
H90 Conductive and sensorineural hearing loss	0.009	0.991	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.009	0.991	0.000
H73.8 Other specified disorders of tympanic membrane	0.009	0.991	0.000
H69.0 Patulous Eustachian tube	0.009	0.991	0.000
H74.4 Polyp of middle ear	0.009	0.991	0.000
H90-H95 Other disorders of ear	0.009	0.991	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.009	0.991	0.000
H73.1 Chronic myringitis	0.009	0.991	0.000
H73.0 Acute myringitis	0.009	0.991	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.009	0.991	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.009	0.991	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.009	0.991	0.000
H68.1 Obstruction of Eustachian tube	0.009	0.991	0.000
H68.0 Eustachian salpingitis	0.009	0.991	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.009	0.991	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.009	0.991	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.009	0.991	0.000
H35 Other retinal disorders	0.000	0.991	0.009
H61 Other disorders of external ear	0.009	0.991	0.000
H80-H83 Diseases of inner ear	0.009	0.991	0.000
H66.4 Suppurative otitis media, unspecified	0.008	0.991	0.000
H66.0 Acute suppurative otitis media	0.008	0.991	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.009	0.991	0.000
H66.3 Other chronic suppurative otitis media	0.008	0.991	0.000
H90.3 Sensorineural hearing loss, bilateral	0.008	0.992	0.000
N20.2 Calculus of kidney with calculus of ureter	0.008	0.992	0.000
H61.3 Acquired stenosis of external ear canal	0.008	0.992	0.000
H35.4 Peripheral retinal degeneration	0.000	0.992	0.008
H65 Nonsuppurative otitis media	0.008	0.992	0.000
H69.8 Other specified disorders of Eustachian tube	0.008	0.992	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.000	0.992	0.008
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.008	0.992	0.000
H90.0 Conductive hearing loss, bilateral	0.008	0.992	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.008	0.992	0.000
H33 Retinal detachments and breaks	0.000	0.992	0.008
H35.2 Other proliferative retinopathy	0.000	0.993	0.007
H35.9 Retinal disorder, unspecified	0.000	0.993	0.007
H90.5 Sensorineural hearing loss, unspecified	0.007	0.993	0.000
H80 Otosclerosis	0.007	0.993	0.000
H93 Other disorders of ear, not elsewhere classified	0.007	0.993	0.000
H33.3 Retinal breaks without detachment	0.000	0.993	0.007
H61.2 Impacted cerumen	0.007	0.993	0.000
H35.6 Retinal haemorrhage	0.000	0.993	0.007
H62 Disorders of external ear in diseases classified elsewhere	0.007	0.993	0.000
I87.1 Compression of vein	0.000	0.993	0.007
H83 Other diseases of inner ear	0.007	0.993	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.007	0.993	0.000
I87 Other disorders of veins	0.000	0.993	0.007
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.007	0.993	0.000
H33.5 Other retinal detachments	0.000	0.993	0.007
H33.2 Serous retinal detachment	0.000	0.993	0.007
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.007	0.993	0.000
H61.1 Non-infective disorders of pinna	0.007	0.993	0.000
H33.0 Retinal detachment with retinal break	0.000	0.993	0.007
H35.0 Background retinopathy and retinal vascular changes	0.000	0.993	0.006
H35.1 Retinopathy of prematurity	0.000	0.993	0.006
H61.8 Other specified disorders of external ear	0.006	0.993	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.006	0.994	0.000
I87.8 Other specified disorders of veins	0.000	0.994	0.006
H61.9 Disorder of external ear, unspecified	0.006	0.994	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.006	0.994	0.000
H93.9 Disorder of ear, unspecified	0.006	0.994	0.000
H65.0 Acute serous otitis media	0.006	0.994	0.000
H93.8 Other specified disorders of ear	0.006	0.994	0.000
H60 Otitis externa	0.006	0.994	0.000
H30-H36 Disorders of choroid and retina	0.000	0.994	0.006
H80.9 Otosclerosis, unspecified	0.006	0.994	0.000
H35.7 Separation of retinal layers	0.000	0.994	0.006
I87.2 Venous insufficiency (chronic) (peripheral)	0.000	0.994	0.006
H65.2 Chronic serous otitis media	0.006	0.994	0.000
H83.8 Other specified diseases of inner ear	0.006	0.994	0.000
T78.2 Anaphylactic shock, unspecified	0.000	0.994	0.006
H65.1 Other acute nonsuppurative otitis media	0.006	0.994	0.000
H65.4 Other chronic nonsuppurative otitis media	0.006	0.994	0.000
H61.0 Perichondritis of external ear	0.006	0.994	0.000
H35.3 Degeneration of macula and posterior pole	0.000	0.994	0.006
H33.4 Traction detachment of retina	0.000	0.994	0.006
H92 Otalgia and effusion of ear	0.005	0.994	0.000
I80 Phlebitis and thrombophlebitis	0.000	0.995	0.005
H31 Other disorders of choroid	0.000	0.995	0.005
H33.1 Retinoschisis and retinal cysts	0.000	0.995	0.005
H80.8 Other otosclerosis	0.005	0.995	0.000
H80.2 Cochlear otosclerosis	0.005	0.995	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.005	0.995	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.005	0.995	0.000
H93.3 Disorders of acoustic nerve	0.005	0.995	0.000
H93.2 Other abnormal auditory perceptions	0.005	0.995	0.000
H93.0 Degenerative and vascular disorders of ear	0.005	0.995	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.005	0.995	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.005	0.995	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
H62.2 Otitis externa in mycoses	0.005	0.995	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.005	0.995	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.005	0.995	0.000
H35.5 Hereditary retinal dystrophy	0.000	0.995	0.005
H81 Disorders of vestibular function	0.005	0.995	0.000
H83.9 Disease of inner ear, unspecified	0.005	0.995	0.000
H83.3 Noise effects on inner ear	0.005	0.995	0.000
H83.2 Labyrinthine dysfunction	0.005	0.995	0.000
H83.1 Labyrinthine fistula	0.005	0.995	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.005	0.995	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.995	0.005
H60.5 Acute otitis externa, non-infective	0.005	0.995	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.005	0.995	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.995	0.005
I87.9 Disorder of vein, unspecified	0.000	0.995	0.005
I87.0 Postphlebitic syndrome	0.000	0.995	0.005
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.005	0.995	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.005	0.995	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.005	0.995	0.000
H95.1 Other disorders following mastoidectomy	0.005	0.995	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.000	0.995	0.005
F17.2 Dependence syndrome	0.000	0.995	0.005
H60.3 Other infective otitis externa	0.005	0.995	0.000
H31.0 Chorioretinal scars	0.000	0.995	0.005
H90.2 Conductive hearing loss, unspecified	0.005	0.995	0.000
H60.4 Cholesteatoma of external ear	0.005	0.995	0.000
H60.2 Malignant otitis externa	0.005	0.995	0.000
H60.0 Abscess of external ear	0.005	0.995	0.000
H66.9 Otitis media, unspecified	0.005	0.995	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.000	0.995	0.005
H83.0 Labyrinthitis	0.005	0.995	0.000
H81.9 Disorder of vestibular function, unspecified	0.005	0.995	0.000
H92.1 Otorrhoea	0.004	0.995	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.995	0.004
H31.8 Other specified disorders of choroid	0.000	0.996	0.004
H65.9 Nonsuppurative otitis media, unspecified	0.004	0.996	0.000
H91 Other hearing loss	0.004	0.996	0.000
M81.98 Osteoporosis, unspecified (Other)	0.004	0.996	0.000
I82 Other venous embolism and thrombosis	0.000	0.996	0.004
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
M81.9 Osteoporosis, unspecified	0.004	0.996	0.000
Z99.3 Dependence on wheelchair	0.004	0.996	0.000
H92.2 Otorrhagia	0.004	0.996	0.000
H30 Chorioretinal inflammation	0.000	0.996	0.004
M81.99 Osteoporosis, unspecified (Site unspecified)	0.004	0.996	0.000
H50.1 Divergent concomitant strabismus	0.004	0.996	0.000
F33 Recurrent depressive disorder	0.004	0.996	0.000
I86 Varicose veins of other sites	0.000	0.996	0.004
S00.8 Superficial injury of other parts of head	0.004	0.996	0.000
H60.8 Other otitis externa	0.004	0.996	0.000
F33.9 Recurrent depressive disorder, unspecified	0.004	0.996	0.000
H31.9 Disorder of choroid, unspecified	0.000	0.996	0.004
H31.4 Choroidal detachment	0.000	0.996	0.004
H31.3 Choroidal haemorrhage and rupture	0.000	0.996	0.004
H31.2 Hereditary choroidal dystrophy	0.000	0.996	0.004
H31.1 Choroidal degeneration	0.000	0.996	0.004
H81.2 Vestibular neuronitis	0.004	0.996	0.000
T78 Adverse effects, not elsewhere classified	0.000	0.996	0.004
I82.8 Embolism and thrombosis of other specified veins	0.000	0.996	0.004
H60.1 Cellulitis of external ear	0.004	0.996	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.004	0.996	0.000
I89.0 Lymphoedema, not elsewhere classified	0.000	0.996	0.004
R15 Faecal incontinence	0.004	0.996	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.004	0.996	0.000
H81.8 Other disorders of vestibular function	0.004	0.996	0.000
H81.4 Vertigo of central origin	0.004	0.996	0.000
H81.3 Other peripheral vertigo	0.004	0.996	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.996	0.004
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.004	0.996	0.000
H60.9 Otitis externa, unspecified	0.004	0.996	0.000
I81 Portal vein thrombosis	0.000	0.996	0.004
T78.0 Anaphylactic shock due to adverse food reaction	0.000	0.996	0.004
I86.8 Varicose veins of other specified sites	0.000	0.996	0.004
H65.3 Chronic mucoid otitis media	0.004	0.996	0.000
I88 Nonspecific lymphadenitis	0.000	0.996	0.004
M81.96 Osteoporosis, unspecified (Lower leg)	0.004	0.996	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.000	0.996	0.004
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.996	0.004
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.996	0.004
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.000	0.996	0.003
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.000	0.996	0.003
S00.1 Contusion of eyelid and periocular area	0.004	0.996	0.000
H36 Retinal disorders in diseases classified elsewhere	0.000	0.996	0.003
I83.1 Varicose veins of lower extremities with inflammation	0.000	0.996	0.003
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.000	0.996	0.003
H91.3 Deaf mutism, not elsewhere classified	0.003	0.997	0.000
H91.2 Sudden idiopathic hearing loss	0.003	0.997	0.000
H91.0 Ototoxic hearing loss	0.003	0.997	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.997	0.003
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.997	0.003
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.997	0.003
Z93.3 Colostomy status	0.003	0.997	0.000
H91.1 Presbycusis	0.003	0.997	0.000
I82.3 Embolism and thrombosis of renal vein	0.000	0.997	0.003
I82.1 Thrombophlebitis migrans	0.000	0.997	0.003
I82.0 Budd-Chiari syndrome	0.000	0.997	0.003
M81.94 Osteoporosis, unspecified (Hand)	0.003	0.997	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.003	0.997	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.003	0.997	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.003	0.997	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.003	0.997	0.000
I83 Varicose veins of lower extremities	0.000	0.997	0.003
H30.8 Other chorioretinal inflammations	0.000	0.997	0.003
H30.2 Posterior cyclitis	0.000	0.997	0.003
H30.1 Disseminated chorioretinal inflammation	0.000	0.997	0.003
H30.0 Focal chorioretinal inflammation	0.000	0.997	0.003
T78.3 Angioneurotic oedema	0.000	0.997	0.003
F33.8 Other recurrent depressive disorders	0.003	0.997	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.003	0.997	0.000
I86.3 Vulval varices	0.000	0.997	0.003
I86.2 Pelvic varices	0.000	0.997	0.003
I86.0 Sublingual varices	0.000	0.997	0.003
H91.8 Other specified hearing loss	0.003	0.997	0.000
S00 Superficial injury of head	0.003	0.997	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.000	0.997	0.003
T78.9 Adverse effect, unspecified	0.000	0.997	0.003
T78.8 Other adverse effects, not elsewhere classified	0.000	0.997	0.003
F17.1 Harmful use	0.000	0.997	0.003
I86.1 Scrotal varices	0.000	0.997	0.003
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.003	0.997	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.003	0.997	0.000
I86.4 Gastric varices	0.000	0.997	0.003
H81.1 Benign paroxysmal vertigo	0.003	0.997	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.000	0.997	0.003
I88.8 Other nonspecific lymphadenitis	0.000	0.997	0.003
I88.1 Chronic lymphadenitis, except mesenteric	0.000	0.997	0.003
I88.0 Nonspecific mesenteric lymphadenitis	0.000	0.997	0.003
I85 Oesophageal varices	0.000	0.997	0.003
M54.59 Low back pain (Site unspecified)	0.003	0.997	0.000
H30.9 Chorioretinal inflammation, unspecified	0.000	0.997	0.003
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.997	0.003
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.997	0.003
D61.9 Aplastic anaemia, unspecified	0.003	0.997	0.000
H34 Retinal vascular occlusions	0.001	0.997	0.002
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.003	0.997	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.000	0.997	0.003
H93.1 Tinnitus	0.003	0.997	0.000
I82.2 Embolism and thrombosis of vena cava	0.000	0.997	0.003
I89.1 Lymphangitis	0.000	0.997	0.003
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.003	0.997	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.003	0.997	0.000
C79 Secondary malignant neoplasm of other sites	0.000	0.997	0.003
J84 Other interstitial pulmonary diseases	0.000	0.997	0.003
M81 Osteoporosis without pathological fracture	0.003	0.997	0.000
Z93.2 Ileostomy status	0.003	0.997	0.000
S00.4 Superficial injury of ear	0.003	0.997	0.000
F17.9 Unspecified mental and behavioural disorder	0.000	0.997	0.003
F17.8 Other mental and behavioural disorders	0.000	0.997	0.003
F17.7 Residual and late-onset psychotic disorder	0.000	0.997	0.003
F17.6 Amnesic syndrome	0.000	0.997	0.003
F17.5 Psychotic disorder	0.000	0.997	0.003
F17.4 Withdrawal state with delirium	0.000	0.997	0.003
F17.3 Withdrawal state	0.000	0.997	0.003
F17.0 Acute intoxication	0.000	0.997	0.003
H81.0 Meniere's disease	0.003	0.997	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.997	0.003
S00.0 Superficial injury of scalp	0.003	0.997	0.000
S00.3 Superficial injury of nose	0.003	0.997	0.000
S00.5 Superficial injury of lip and oral cavity	0.002	0.997	0.000
S02.60 Fracture of mandible (closed)	0.003	0.997	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.997	0.003
T45.0 Antiallergic and antiemetic drugs	0.002	0.997	0.000
M81.0 Postmenopausal osteoporosis	0.002	0.997	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.002	0.998	0.000
C79.6 Secondary malignant neoplasm of ovary	0.000	0.998	0.002
J84.8 Other specified interstitial pulmonary diseases	0.000	0.998	0.002
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.002	0.998	0.000
I85.0 Oesophageal varices with bleeding	0.000	0.998	0.002
Z48.0 Attention to surgical dressings and sutures	0.000	0.998	0.002
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.000	0.998	0.002
H92.0 Otalgia	0.002	0.998	0.000
H34.9 Retinal vascular occlusion, unspecified	0.001	0.998	0.001
H34.0 Transient retinal artery occlusion	0.001	0.998	0.001
Z03.3 Observation for suspected nervous system disorder	0.002	0.998	0.000
S42.10 Fracture of scapula (closed)	0.000	0.998	0.002
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.998	0.002
T78.4 Allergy, unspecified	0.000	0.998	0.002
M84.1 Nonunion of fracture [pseudarthrosis]	0.002	0.998	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.998	0.002
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.998	0.002
H34.1 Central retinal artery occlusion	0.001	0.998	0.001
J84.0 Alveolar and parietoalveolar conditions	0.000	0.998	0.002
M81.8 Other osteoporosis	0.002	0.998	0.000
M81.6 Localised osteoporosis [Lequesne]	0.002	0.998	0.000
M81.5 Idiopathic osteoporosis	0.002	0.998	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.002	0.998	0.000
M81.1 Postoophorectomy osteoporosis	0.002	0.998	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.002	0.998	0.000
O26.9 Pregnancy-related condition, unspecified	0.002	0.998	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.000	0.998	0.002
C79.2 Secondary malignant neoplasm of skin	0.000	0.998	0.002
H34.8 Other retinal vascular occlusions	0.002	0.998	0.000
Z93.9 Artificial opening status, unspecified	0.002	0.998	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.002	0.998	0.000
K91.4 Colostomy and enterostomy malfunction	0.002	0.998	0.000
M81.2 Osteoporosis of disuse	0.002	0.998	0.000
Z93 Artificial opening status	0.002	0.998	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.002	0.998	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.002	0.998	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.002	0.998	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.002	0.998	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.002	0.998	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.002	0.998	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.002	0.998	0.000
H34.2 Other retinal artery occlusions	0.001	0.998	0.001
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.002	0.998	0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.000	0.998	0.002
S00.7 Multiple superficial injuries of head	0.002	0.998	0.000
K91.1 Postgastric surgery syndromes	0.002	0.998	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.000	0.998	0.002
H50.5 Heterophoria	0.002	0.998	0.000
Z52.4 Kidney donor	0.002	0.998	0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.000	0.998	0.002
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.002	0.998	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.998	0.002
D23.2 Skin of ear and external auricular canal	0.000	0.998	0.002
N36.8 Other specified disorders of urethra	0.000	0.998	0.002
H50 Other strabismus	0.002	0.998	0.000
C71.9 Brain, unspecified	0.000	0.998	0.002
Z73.9 Problem related to life-management difficulty, unspecified	0.002	0.998	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.000	0.998	0.002
K91.0 Vomiting following gastro-intestinal surgery	0.002	0.998	0.000
M81.4 Drug-induced osteoporosis	0.002	0.998	0.000
N39.3 Stress incontinence	0.000	0.998	0.002
S02.6 Fracture of mandible	0.002	0.998	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.002	0.998	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.002	0.998	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.998	0.002
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.998	0.002
N36.2 Urethral caruncle	0.000	0.998	0.002
Z93.4 Other artificial openings of gastro-intestinal tract status	0.002	0.998	0.000
K91.3 Postoperative intestinal obstruction	0.002	0.998	0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.000	0.998	0.002
M65.9 Synovitis and tenosynovitis, unspecified	0.000	0.998	0.002
Z73.8 Other problems related to life-management difficulty	0.002	0.998	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.002	0.998	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.002	0.998	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.002	0.998	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.002	0.998	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.002	0.998	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.002	0.998	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.002	0.998	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.002	0.998	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.002	0.998	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.002	0.998	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.002	0.998	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.002	0.998	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.002	0.998	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.002	0.998	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.58 Idiopathic osteoporosis (Other)	0.002	0.998	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.002	0.998	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.002	0.998	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.002	0.998	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.002	0.998	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.002	0.998	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.002	0.998	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.002	0.998	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.002	0.998	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.002	0.998	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.002	0.998	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.002	0.998	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.002	0.998	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.002	0.998	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.002	0.998	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.002	0.998	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.002	0.998	0.000
M81.89 Other osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.88 Other osteoporosis (Other)	0.002	0.998	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.86 Other osteoporosis (Lower leg)	0.002	0.998	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.84 Other osteoporosis (Hand)	0.002	0.998	0.000
M81.83 Other osteoporosis (Forearm)	0.002	0.998	0.000
M81.82 Other osteoporosis (Upper arm)	0.002	0.998	0.000
M81.81 Other osteoporosis (Shoulder region)	0.002	0.998	0.000
M81.80 Other osteoporosis (Multiple sites)	0.002	0.998	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.998	0.002
N21.0 Calculus in bladder	0.002	0.998	0.000
D23.1 Skin of eyelid, including canthus	0.000	0.998	0.002
C15.9 Oesophagus, unspecified	0.000	0.998	0.002
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.002	0.998	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.002	0.998	0.000
D59.1 Other autoimmune haemolytic anaemias	0.002	0.998	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.002	0.998	0.000
M81.28 Osteoporosis of disuse (Other)	0.002	0.998	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.002	0.998	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.002	0.998	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.002	0.998	0.000
M81.24 Osteoporosis of disuse (Hand)	0.002	0.998	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.002	0.998	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.002	0.998	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.002	0.998	0.000
N28.8 Other specified disorders of kidney and ureter	0.000	0.998	0.002
Z93.8 Other artificial opening status	0.002	0.998	0.000
S92.30 Fracture of metatarsal bone (closed)	0.000	0.998	0.002
K91.2 Postsurgical malabsorption, not elsewhere classified	0.002	0.998	0.000
D23.3 Skin of other and unspecified parts of face	0.000	0.998	0.002
N95.8 Other specified menopausal and perimenopausal disorders	0.002	0.998	0.000
S42.1 Fracture of scapula	0.000	0.998	0.002
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.002	0.998	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.002	0.998	0.000
G50.0 Trigeminal neuralgia	0.002	0.998	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.002	0.998	0.000
K91.5 Postcholecystectomy syndrome	0.002	0.998	0.000
T39.1 4-Aminophenol derivatives	0.002	0.998	0.000
D61 Other aplastic anaemias	0.002	0.998	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.000	0.998	0.002
Z93.5 Cystostomy status	0.002	0.998	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.000	0.998	0.002
D23.6 Skin of upper limb, including shoulder	0.000	0.998	0.002
H50.8 Other specified strabismus	0.002	0.998	0.000
H50.6 Mechanical strabismus	0.002	0.998	0.000
H50.4 Other and unspecified heterotropia	0.002	0.998	0.000
H50.3 Intermittent heterotropia	0.002	0.998	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.998	0.002
N76.2 Acute vulvitis	0.002	0.998	0.000
M84 Disorders of continuity of bone	0.002	0.998	0.000
N36 Other disorders of urethra	0.000	0.998	0.002
M81.48 Drug-induced osteoporosis (Other)	0.001	0.998	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.001	0.998	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.001	0.998	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.001	0.998	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.001	0.998	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.001	0.998	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.001	0.998	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.001	0.998	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.002	0.998	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.002	0.998	0.000
S02.61 Fracture of mandible (open)	0.001	0.998	0.000
Z75.5 Holiday relief care	0.002	0.998	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.000	0.998	0.001
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.000	0.998	0.001
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.000	0.998	0.001
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.000	0.998	0.001
M81.20 Osteoporosis of disuse (Multiple sites)	0.001	0.998	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.001	0.998	0.000
H40.2 Primary angle-closure glaucoma	0.000	0.998	0.002
I85.9 Oesophageal varices without bleeding	0.000	0.998	0.002
M81.49 Drug-induced osteoporosis (Site unspecified)	0.001	0.998	0.000
N36.3 Prolapsed urethral mucosa	0.000	0.998	0.002
S00.9 Superficial injury of head, part unspecified	0.002	0.998	0.000
F30 Manic episode	0.002	0.998	0.000
F39 Unspecified mood [affective] disorder	0.002	0.998	0.000
F30-F39 Mood [affective] disorders	0.002	0.998	0.000
N36.9 Urethral disorder, unspecified	0.000	0.998	0.002
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.002	0.998	0.000
F30.0 Hypomania	0.001	0.998	0.000
K81.1 Chronic cholecystitis	0.000	0.998	0.002
B37.0 Candidal stomatitis	0.002	0.998	0.000
D61.1 Drug-induced aplastic anaemia	0.001	0.998	0.000
S05.9 Injury of eye and orbit, part unspecified	0.001	0.998	0.000
S05 Injury of eye and orbit	0.002	0.998	0.000
Z73 Problems related to life-management difficulty	0.002	0.998	0.000
H36.0 Diabetic retinopathy	0.000	0.998	0.002
O24.4 Diabetes mellitus arising in pregnancy	0.001	0.998	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.002	0.998	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.001	0.998	0.000
N80.9 Endometriosis, unspecified	0.000	0.998	0.002
S02.7 Multiple fractures involving skull and facial bones	0.001	0.998	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.998	0.001
S42.11 Fracture of scapula (open)	0.000	0.998	0.001
C34.0 Main bronchus	0.000	0.998	0.001
D61.8 Other specified aplastic anaemias	0.001	0.998	0.000
D61.3 Idiopathic aplastic anaemia	0.001	0.998	0.000
D61.2 Aplastic anaemia due to other external agents	0.001	0.998	0.000
D61.0 Constitutional aplastic anaemia	0.001	0.998	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations