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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2834188
log Bayes Factor = 0.979999
Chromosome 21   position 34,689,253  (GRCh37) Explore rs2834188 on Ensembl!
Variant rs2834188 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
F30-F39 Mood [affective] disorders
0.000 0.105 0.895
F31 Bipolar affective disorder
0.000 0.105 0.895
F33 Recurrent depressive disorder
0.000 0.114 0.886
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.000 0.134 0.866
F30 Manic episode
0.000 0.147 0.853
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.000 0.162 0.838
F31.0 Bipolar affective disorder, current episode hypomanic
0.000 0.183 0.817
F31.9 Bipolar affective disorder, unspecified
0.000 0.232 0.768
F31.6 Bipolar affective disorder, current episode mixed
0.000 0.234 0.766
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.000 0.243 0.757
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.000 0.256 0.743
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.000 0.261 0.739
F30.2 Mania with psychotic symptoms
0.000 0.269 0.731
F33.0 Recurrent depressive disorder, current episode mild
0.000 0.269 0.731
F30.9 Manic episode, unspecified
0.000 0.280 0.720
F30.1 Mania without psychotic symptoms
0.000 0.283 0.717
F32 Depressive episode
0.000 0.283 0.717
F38 Other mood [affective] disorders
0.000 0.298 0.702
F33.8 Other recurrent depressive disorders
0.000 0.300 0.700
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.000 0.330 0.670
F33.4 Recurrent depressive disorder, currently in remission
0.000 0.340 0.659
F34 Persistent mood [affective] disorders
0.000 0.344 0.656
F30.0 Hypomania
0.000 0.344 0.656
F32.0 Mild depressive episode
0.000 0.348 0.652
F31.8 Other bipolar affective disorders
0.000 0.352 0.648
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.000 0.365 0.635
F32.8 Other depressive episodes
0.000 0.372 0.628
F30.8 Other manic episodes
0.000 0.389 0.611
F39 Unspecified mood [affective] disorder
0.000 0.417 0.583
F31.7 Bipolar affective disorder, currently in remission
0.000 0.418 0.581
F33.9 Recurrent depressive disorder, unspecified
0.000 0.420 0.580
F33.1 Recurrent depressive disorder, current episode moderate
0.000 0.430 0.570
F32.1 Moderate depressive episode
0.000 0.434 0.566
F38.0 Other single mood [affective] disorders
0.000 0.436 0.563
Chapter V Mental and behavioural disorders
0.000 0.465 0.535
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.000 0.493 0.507
F38.1 Other recurrent mood [affective] disorders
0.000 0.497 0.503
F38.8 Other specified mood [affective] disorders
0.000 0.497 0.503
F34.0 Cyclothymia
0.000 0.498 0.501
F00-F09 Organic, including symptomatic, mental disorders
0.000 0.503 0.497
F32.2 Severe depressive episode without psychotic symptoms
0.000 0.529 0.471
F34.9 Persistent mood [affective] disorder, unspecified
0.000 0.529 0.470
F34.8 Other persistent mood [affective] disorders
0.000 0.529 0.470
F10 Mental and behavioural disorders due to use of alcohol
0.000 0.537 0.463
F02 Dementia in other diseases classified elsewhere
0.000 0.537 0.463
F34.1 Dysthymia
0.000 0.549 0.450
F10.3 Withdrawal state
0.000 0.559 0.441
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.000 0.564 0.436
F02.3 Dementia in Parkinson's disease
0.000 0.567 0.433
F10.5 Psychotic disorder
0.000 0.570 0.430
F32.3 Severe depressive episode with psychotic symptoms
0.000 0.574 0.426
F10.2 Dependence syndrome
0.000 0.579 0.421
F11 Mental and behavioural disorders due to use of opioids
0.000 0.584 0.416
F01 Vascular dementia
0.000 0.586 0.414
F03 Unspecified dementia
0.000 0.589 0.411
F70-F79 Mental retardation
0.000 0.590 0.410
F17 Mental and behavioural disorders due to use of tobacco
0.000 0.593 0.407
F06.7 Mild cognitive disorder
0.000 0.605 0.395
F80-F89 Disorders of psychological development
0.000 0.610 0.390
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.000 0.613 0.387
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.000 0.613 0.387
F02.8 Dementia in other specified diseases classified elsewhere
0.000 0.615 0.385
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.000 0.616 0.384
F17.2 Dependence syndrome
0.000 0.626 0.374
F12 Mental and behavioural disorders due to use of cannabinoids
0.000 0.627 0.373
F18 Mental and behavioural disorders due to use of volatile solvents
0.000 0.637 0.363
F16 Mental and behavioural disorders due to use of hallucinogens
0.000 0.637 0.363
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.000 0.639 0.361
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.000 0.644 0.356
F09 Unspecified organic or symptomatic mental disorder
0.000 0.645 0.355
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease
0.000 0.648 0.352
F14 Mental and behavioural disorders due to use of cocaine
0.000 0.649 0.351
F01.9 Vascular dementia, unspecified
0.000 0.651 0.349
F99-F99 Unspecified mental disorder
0.000 0.655 0.345
F11.2 Dependence syndrome
0.000 0.656 0.344
F17.0 Acute intoxication
0.000 0.660 0.340
F10.6 Amnesic syndrome
0.000 0.667 0.333
F10.8 Other mental and behavioural disorders
0.000 0.668 0.332
F02.4 Dementia in human immunodeficiency virus [HIV] disease
0.000 0.668 0.332
F02.2 Dementia in Huntington's disease
0.000 0.668 0.332
F02.1 Dementia in Creutzfeldt-Jakob disease
0.000 0.668 0.332
F10.7 Residual and late-onset psychotic disorder
0.000 0.670 0.330
F06.2 Organic delusional [schizophrenia-like] disorder
0.000 0.674 0.326
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.000 0.675 0.325
F79 Unspecified mental retardation
0.000 0.680 0.320
F19.1 Harmful use
0.000 0.681 0.319
F11.3 Withdrawal state
0.000 0.684 0.315
F22 Persistent delusional disorders
0.000 0.687 0.313
F06.6 Organic emotionally labile [asthenic] disorder
0.000 0.687 0.312
F06.5 Organic dissociative disorder
0.000 0.687 0.312
F06.4 Organic anxiety disorder
0.000 0.687 0.312
F06.1 Organic catatonic disorder
0.000 0.687 0.312
F06.0 Organic hallucinosis
0.000 0.687 0.312
F25 Schizoaffective disorders
0.000 0.691 0.309
F11.0 Acute intoxication
0.000 0.692 0.308
F01.1 Multi-infarct dementia
0.000 0.693 0.307
F60-F69 Disorders of adult personality and behaviour
0.000 0.700 0.300
F17.3 Withdrawal state
0.000 0.701 0.298
F81 Specific developmental disorders of scholastic skills
0.000 0.702 0.298
F11.9 Unspecified mental and behavioural disorder
0.000 0.702 0.298
F11.8 Other mental and behavioural disorders
0.000 0.702 0.298
F11.7 Residual and late-onset psychotic disorder
0.000 0.702 0.298
F11.6 Amnesic syndrome
0.000 0.702 0.298
F11.5 Psychotic disorder
0.000 0.702 0.298
F11.4 Withdrawal state with delirium
0.000 0.702 0.298
F01.8 Other vascular dementia
0.000 0.703 0.297
F01.3 Mixed cortical and subcortical vascular dementia
0.000 0.703 0.297
F01.2 Subcortical vascular dementia
0.000 0.703 0.297
F01.0 Vascular dementia of acute onset
0.000 0.703 0.297
F78 Other mental retardation
0.000 0.706 0.294
F73 Profound mental retardation
0.000 0.706 0.294
F72 Severe mental retardation
0.000 0.706 0.294
F71 Moderate mental retardation
0.000 0.706 0.294
F70 Mild mental retardation
0.000 0.706 0.294
F19.5 Psychotic disorder
0.000 0.706 0.294
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.000 0.706 0.294
F21 Schizotypal disorder
0.000 0.707 0.293
F12.1 Harmful use
0.000 0.707 0.293
F17.8 Other mental and behavioural disorders
0.000 0.708 0.292
F17.7 Residual and late-onset psychotic disorder
0.000 0.708 0.292
F17.6 Amnesic syndrome
0.000 0.708 0.292
F17.5 Psychotic disorder
0.000 0.708 0.292
F17.4 Withdrawal state with delirium
0.000 0.708 0.292
F90 Hyperkinetic disorders
0.000 0.708 0.292
F06.3 Organic mood [affective] disorders
0.000 0.710 0.290
F84 Pervasive developmental disorders
0.000 0.711 0.289
F89 Unspecified disorder of psychological development
0.000 0.720 0.280
F88 Other disorders of psychological development
0.000 0.720 0.280
F83 Mixed specific developmental disorders
0.000 0.720 0.280
F82 Specific developmental disorder of motor function
0.000 0.720 0.280
F17.9 Unspecified mental and behavioural disorder
0.000 0.720 0.280
F11.1 Harmful use
0.000 0.721 0.279
F02.0 Dementia in Pick's disease
0.000 0.722 0.278
F28 Other nonorganic psychotic disorders
0.000 0.722 0.278
F24 Induced delusional disorder
0.000 0.722 0.278
F19.9 Unspecified mental and behavioural disorder
0.000 0.723 0.277
F19.8 Other mental and behavioural disorders
0.000 0.723 0.277
F19.7 Residual and late-onset psychotic disorder
0.000 0.723 0.277
F19.6 Amnesic syndrome
0.000 0.723 0.277
F19.4 Withdrawal state with delirium
0.000 0.723 0.277
F19.0 Acute intoxication
0.000 0.723 0.277
F98 Other behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.000 0.724 0.276
F94 Disorders of social functioning with onset specific to childhood and adolescence
0.000 0.725 0.275
F93 Emotional disorders with onset specific to childhood
0.000 0.725 0.275
F92 Mixed disorders of conduct and emotions
0.000 0.725 0.275
F91 Conduct disorders
0.000 0.725 0.275
F00 Dementia in Alzheimer's disease
0.000 0.725 0.275
F25.9 Schizoaffective disorder, unspecified
0.000 0.726 0.274
F13.2 Dependence syndrome
0.000 0.730 0.270
F12.9 Unspecified mental and behavioural disorder
0.000 0.732 0.268
F12.8 Other mental and behavioural disorders
0.000 0.732 0.268
F12.7 Residual and late-onset psychotic disorder
0.000 0.732 0.268
F12.6 Amnesic syndrome
0.000 0.732 0.268
F12.5 Psychotic disorder
0.000 0.732 0.268
F12.4 Withdrawal state with delirium
0.000 0.732 0.268
F12.3 Withdrawal state
0.000 0.732 0.268
F22.0 Delusional disorder
0.000 0.733 0.267
F19.3 Withdrawal state
0.000 0.736 0.264
F12.2 Dependence syndrome
0.000 0.739 0.261
F16.9 Unspecified mental and behavioural disorder
0.000 0.739 0.260
F16.8 Other mental and behavioural disorders
0.000 0.739 0.260
F16.7 Residual and late-onset psychotic disorder
0.000 0.739 0.260
F16.6 Amnesic syndrome
0.000 0.739 0.260
F16.5 Psychotic disorder
0.000 0.739 0.260
F16.4 Withdrawal state with delirium
0.000 0.739 0.260
F16.3 Withdrawal state
0.000 0.739 0.260
F16.2 Dependence syndrome
0.000 0.739 0.260
F16.1 Harmful use
0.000 0.739 0.260
F16.0 Acute intoxication
0.000 0.739 0.260
F18.9 Unspecified mental and behavioural disorder
0.000 0.739 0.260
F18.8 Other mental and behavioural disorders
0.000 0.739 0.260
F18.7 Residual and late-onset psychotic disorder
0.000 0.739 0.260
F18.6 Amnesic syndrome
0.000 0.739 0.260
F18.5 Psychotic disorder
0.000 0.739 0.260
F18.4 Withdrawal state with delirium
0.000 0.739 0.260
F18.3 Withdrawal state
0.000 0.739 0.260
F18.2 Dependence syndrome
0.000 0.739 0.260
F18.1 Harmful use
0.000 0.739 0.260
F18.0 Acute intoxication
0.000 0.739 0.260
F13.9 Unspecified mental and behavioural disorder
0.000 0.741 0.259
F13.8 Other mental and behavioural disorders
0.000 0.741 0.259
F13.7 Residual and late-onset psychotic disorder
0.000 0.741 0.259
F13.6 Amnesic syndrome
0.000 0.741 0.259
F13.5 Psychotic disorder
0.000 0.741 0.259
F13.4 Withdrawal state with delirium
0.000 0.741 0.259
F13.0 Acute intoxication
0.000 0.741 0.259
F12.0 Acute intoxication
0.000 0.744 0.256
F79.9 Unspecified mental retardation (Without mention of impairment of behaviour)
0.000 0.745 0.255
F80 Specific developmental disorders of speech and language
0.000 0.745 0.255
F95 Tic disorders
0.000 0.746 0.254
F13.1 Harmful use
0.000 0.746 0.254
F14.9 Unspecified mental and behavioural disorder
0.000 0.748 0.252
F14.8 Other mental and behavioural disorders
0.000 0.748 0.252
F14.7 Residual and late-onset psychotic disorder
0.000 0.748 0.252
F14.6 Amnesic syndrome
0.000 0.748 0.252
F14.5 Psychotic disorder
0.000 0.748 0.252
F14.4 Withdrawal state with delirium
0.000 0.748 0.252
F14.3 Withdrawal state
0.000 0.748 0.252
F14.0 Acute intoxication
0.000 0.748 0.252
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease
0.000 0.748 0.251
F13.3 Withdrawal state
0.000 0.749 0.251
F14.2 Dependence syndrome
0.000 0.749 0.251
F29 Unspecified nonorganic psychosis
0.000 0.750 0.250
F10.4 Withdrawal state with delirium
0.000 0.751 0.249
F19.2 Dependence syndrome
0.000 0.757 0.242
F14.1 Harmful use
0.000 0.759 0.241
F23 Acute and transient psychotic disorders
0.000 0.761 0.239
F20 Schizophrenia
0.000 0.762 0.238
F10.9 Unspecified mental and behavioural disorder
0.000 0.764 0.235
F10.0 Acute intoxication
0.000 0.765 0.235
F15.9 Unspecified mental and behavioural disorder
0.000 0.767 0.233
F15.8 Other mental and behavioural disorders
0.000 0.767 0.233
F15.7 Residual and late-onset psychotic disorder
0.000 0.767 0.233
F15.6 Amnesic syndrome
0.000 0.767 0.233
F15.5 Psychotic disorder
0.000 0.767 0.233
F15.4 Withdrawal state with delirium
0.000 0.767 0.233
F15.3 Withdrawal state
0.000 0.767 0.233
F15.2 Dependence syndrome
0.000 0.767 0.233
F15.0 Acute intoxication
0.000 0.767 0.233
F81.9 Developmental disorder of scholastic skills, unspecified
0.000 0.768 0.232
F79.8 Unspecified mental retardation (Other impairments of behaviour)
0.000 0.771 0.229
F79.1 Unspecified mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.000 0.771 0.229
F79.0 Unspecified mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.000 0.771 0.229
F25.0 Schizoaffective disorder, manic type
0.000 0.771 0.229
F90.0 Disturbance of activity and attention
0.000 0.774 0.226
F22.8 Other persistent delusional disorders
0.000 0.775 0.225
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.000 0.777 0.223
F25.8 Other schizoaffective disorders
0.000 0.778 0.221
F84.5 Asperger's syndrome
0.000 0.779 0.221
F25.2 Schizoaffective disorder, mixed type
0.000 0.783 0.216
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.000 0.785 0.215
F65 Disorders of sexual preference
0.000 0.785 0.215
F63 Habit and impulse disorders
0.000 0.785 0.215
F81.8 Other developmental disorders of scholastic skills
0.000 0.786 0.214
F81.3 Mixed disorder of scholastic skills
0.000 0.786 0.214
F81.2 Specific disorder of arithmetical skills
0.000 0.786 0.214
F81.1 Specific spelling disorder
0.000 0.786 0.214
F81.0 Specific reading disorder
0.000 0.786 0.214
F22.9 Persistent delusional disorder, unspecified
0.000 0.787 0.213
F68 Other disorders of adult personality and behaviour
0.000 0.788 0.212
F60 Specific personality disorders
0.000 0.789 0.211
F70.9 Mild mental retardation (Without mention of impairment of behaviour)
0.000 0.789 0.211
F70.8 Mild mental retardation (Other impairments of behaviour)
0.000 0.789 0.211
F70.1 Mild mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.000 0.789 0.211
F70.0 Mild mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.000 0.789 0.211
F71.9 Moderate mental retardation (Without mention of impairment of behaviour)
0.000 0.789 0.211
F71.8 Moderate mental retardation (Other impairments of behaviour)
0.000 0.789 0.211
F71.1 Moderate mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.000 0.789 0.211
F71.0 Moderate mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.000 0.789 0.211
F72.9 Severe mental retardation (Without mention of impairment of behaviour)
0.000 0.789 0.211
F72.8 Severe mental retardation (Other impairments of behaviour)
0.000 0.789 0.211
F72.1 Severe mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.000 0.789 0.211
F72.0 Severe mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.000 0.789 0.211
F73.9 Profound mental retardation (Without mention of impairment of behaviour)
0.000 0.789 0.211
F73.8 Profound mental retardation (Other impairments of behaviour)
0.000 0.789 0.211
F73.1 Profound mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.000 0.789 0.211
F73.0 Profound mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.000 0.789 0.211
F78.9 Other mental retardation (Without mention of impairment of behaviour)
0.000 0.789 0.211
F78.8 Other mental retardation (Other impairments of behaviour)
0.000 0.789 0.211
F78.1 Other mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.000 0.789 0.211
F78.0 Other mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.000 0.789 0.211
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction
0.000 0.789 0.211
F07.1 Postencephalitic syndrome
0.000 0.789 0.211
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction
0.000 0.790 0.210
F90.9 Hyperkinetic disorder, unspecified
0.000 0.791 0.209
F90.8 Other hyperkinetic disorders
0.000 0.791 0.209
F90.1 Hyperkinetic conduct disorder
0.000 0.791 0.209
F99 Mental disorder, not otherwise specified
0.000 0.791 0.209
F84.9 Pervasive developmental disorder, unspecified
0.000 0.793 0.207
F84.8 Other pervasive developmental disorders
0.000 0.793 0.207
F84.4 Overactive disorder associated with mental retardation and stereotyped movements
0.000 0.793 0.207
F84.3 Other childhood disintegrative disorder
0.000 0.793 0.207
F84.2 Rett's syndrome
0.000 0.793 0.207
F84.1 Atypical autism
0.000 0.793 0.207
F61 Mixed and other personality disorders
0.000 0.796 0.204
F69 Unspecified disorder of adult personality and behaviour
0.000 0.796 0.203
F84.0 Childhood autism
0.000 0.799 0.201
F98.5 Stuttering [stammering]
0.000 0.801 0.199
F64 Gender identity disorders
0.000 0.801 0.199
F98.9 Unspecified behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.000 0.802 0.198
F98.8 Other specified behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.000 0.802 0.198
F98.6 Cluttering
0.000 0.802 0.198
F98.4 Stereotyped movement disorders
0.000 0.802 0.198
F98.3 Pica of infancy and childhood
0.000 0.802 0.198
F98.2 Feeding disorder of infancy and childhood
0.000 0.802 0.198
F98.1 Nonorganic encopresis
0.000 0.802 0.198
F98.0 Nonorganic enuresis
0.000 0.802 0.198
F91.9 Conduct disorder, unspecified
0.000 0.802 0.197
F91.8 Other conduct disorders
0.000 0.802 0.197
F91.3 Oppositional defiant disorder
0.000 0.802 0.197
F91.2 Socialised conduct disorder
0.000 0.802 0.197
F91.1 Unsocialised conduct disorder
0.000 0.802 0.197
F91.0 Conduct disorder confined to the family context
0.000 0.802 0.197
F92.9 Mixed disorder of conduct and emotions, unspecified
0.000 0.802 0.197
F92.8 Other mixed disorders of conduct and emotions
0.000 0.802 0.197
F92.0 Depressive conduct disorder
0.000 0.802 0.197
F93.9 Childhood emotional disorder, unspecified
0.000 0.802 0.197
F93.8 Other childhood emotional disorders
0.000 0.802 0.197
F93.3 Sibling rivalry disorder
0.000 0.802 0.197
F93.2 Social anxiety disorder of childhood
0.000 0.802 0.197
F93.1 Phobic anxiety disorder of childhood
0.000 0.802 0.197
F93.0 Separation anxiety disorder of childhood
0.000 0.802 0.197
F94.9 Childhood disorder of social functioning, unspecified
0.000 0.802 0.197
F94.8 Other childhood disorders of social functioning
0.000 0.802 0.197
F94.2 Disinhibited attachment disorder of childhood
0.000 0.802 0.197
F94.1 Reactive attachment disorder of childhood
0.000 0.802 0.197
F94.0 Elective mutism
0.000 0.802 0.197
F62 Enduring personality changes, not attributable to brain damage and disease
0.000 0.803 0.197
F00.1 Dementia in Alzheimer's disease with late onset
0.000 0.803 0.196
F15.1 Harmful use
0.000 0.805 0.194
F07.0 Organic personality disorder
0.000 0.814 0.185
F20.5 Residual schizophrenia
0.000 0.815 0.185
F80.2 Receptive language disorder
0.000 0.816 0.184
F80.9 Developmental disorder of speech and language, unspecified
0.000 0.817 0.183
F80.8 Other developmental disorders of speech and language
0.000 0.817 0.183
F80.3 Acquired aphasia with epilepsy [Landau-Kleffner]
0.000 0.817 0.183
F80.0 Specific speech articulation disorder
0.000 0.817 0.183
F07.2 Postconcussional syndrome
0.000 0.817 0.182
F95.9 Tic disorder, unspecified
0.000 0.817 0.182
F95.8 Other tic disorders
0.000 0.817 0.182
F95.1 Chronic motor or vocal tic disorder
0.000 0.817 0.182
F95.0 Transient tic disorder
0.000 0.817 0.182
F05 Delirium, not induced by alcohol and other psychoactive substances
0.000 0.819 0.180
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia
0.000 0.821 0.179
F00.9 Dementia in Alzheimer's disease, unspecified
0.000 0.821 0.179
F00.2 Dementia in Alzheimer's disease, atypical or mixed type
0.000 0.824 0.176
F00.0 Dementia in Alzheimer's disease with early onset
0.000 0.824 0.176
F60.0 Paranoid personality disorder
0.000 0.825 0.175
F23.3 Other acute predominantly delusional psychotic disorders
0.000 0.828 0.171
F23.2 Acute schizophrenia-like psychotic disorder
0.000 0.828 0.171
F20.6 Simple schizophrenia
0.000 0.829 0.171
F20.4 Postschizophrenic depression
0.000 0.829 0.171
F20.3 Undifferentiated schizophrenia
0.000 0.829 0.171
F20.1 Hebephrenic schizophrenia
0.000 0.829 0.171
F20.8 Other schizophrenia
0.000 0.831 0.168
F20.0 Paranoid schizophrenia
0.000 0.832 0.167
F20.2 Catatonic schizophrenia
0.000 0.834 0.166
F55 Abuse of non-dependence-producing substances
0.000 0.835 0.165
F60.6 Anxious [avoidant] personality disorder
0.000 0.837 0.163
F25.1 Schizoaffective disorder, depressive type
0.000 0.837 0.162
F60.8 Other specific personality disorders
0.000 0.838 0.162
F95.2 Combined vocal and multiple motor tic disorder [de la Tourette]
0.000 0.838 0.161
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.000 0.839 0.160
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors
0.000 0.840 0.160
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere
0.000 0.840 0.160
F23.8 Other acute and transient psychotic disorders
0.000 0.840 0.160
F60.3 Emotionally unstable personality disorder
0.000 0.841 0.159
F23.9 Acute and transient psychotic disorder, unspecified
0.000 0.843 0.156
F80.1 Expressive language disorder
0.000 0.844 0.156
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia
0.000 0.844 0.155
F63.9 Habit and impulse disorder, unspecified
0.000 0.846 0.154
F63.8 Other habit and impulse disorders
0.000 0.846 0.154
F63.3 Trichotillomania
0.000 0.846 0.154
F63.2 Pathological stealing [kleptomania]
0.000 0.846 0.154
F63.1 Pathological fire-setting [pyromania]
0.000 0.846 0.154
F63.0 Pathological gambling
0.000 0.846 0.154
F65.9 Disorder of sexual preference, unspecified
0.000 0.846 0.154
F65.8 Other disorders of sexual preference
0.000 0.846 0.154
F65.6 Multiple disorders of sexual preference
0.000 0.846 0.154
F65.5 Sadomasochism
0.000 0.846 0.154
F65.4 Paedophilia
0.000 0.846 0.154
F65.3 Voyeurism
0.000 0.846 0.154
F65.2 Exhibitionism
0.000 0.846 0.154
F65.1 Fetishistic transvestism
0.000 0.846 0.154
F65.0 Fetishism
0.000 0.846 0.154
F66.9 Psychosexual development disorder, unspecified
0.000 0.846 0.154
F66.8 Other psychosexual development disorders
0.000 0.846 0.154
F66.2 Sexual relationship disorder
0.000 0.846 0.154
F66.1 Egodystonic sexual orientation
0.000 0.846 0.154
F66.0 Sexual maturation disorder
0.000 0.846 0.154
F68.8 Other specified disorders of adult personality and behaviour
0.000 0.848 0.152
F68.0 Elaboration of physical symptoms for psychological reasons
0.000 0.848 0.152
F60.1 Schizoid personality disorder
0.000 0.848 0.152
F68.1 Intentional production or feigning of symptoms or disabilities, either physical or psychological [factitious disorder]
0.000 0.851 0.149
F60.7 Dependent personality disorder
0.000 0.852 0.147
F60.4 Histrionic personality disorder
0.000 0.853 0.147
F60.2 Dissocial personality disorder
0.000 0.855 0.144
F51 Nonorganic sleep disorders
0.000 0.856 0.143
F64.9 Gender identity disorder, unspecified
0.000 0.857 0.142
F64.8 Other gender identity disorders
0.000 0.857 0.142
F64.2 Gender identity disorder of childhood
0.000 0.857 0.142
F64.1 Dual-role transvestism
0.000 0.857 0.142
F62.8 Other enduring personality changes
0.000 0.859 0.141
F62.1 Enduring personality change after psychiatric illness
0.000 0.859 0.141
F62.0 Enduring personality change after catastrophic experience
0.000 0.859 0.141
K70.3 Alcoholic cirrhosis of liver
0.000 0.862 0.138
K70 Alcoholic liver disease
0.000 0.866 0.134
K70.4 Alcoholic hepatic failure
0.000 0.869 0.131
F05.8 Other delirium
0.000 0.873 0.127
F64.0 Transsexualism
0.000 0.874 0.126
F50 Eating disorders
0.000 0.876 0.123
F60.9 Personality disorder, unspecified
0.000 0.876 0.124
F62.9 Enduring personality change, unspecified
0.000 0.877 0.123
F05.0 Delirium not superimposed on dementia, so described
0.000 0.877 0.122
F05.1 Delirium superimposed on dementia
0.000 0.878 0.122
F20.9 Schizophrenia, unspecified
0.000 0.879 0.121
K70-K77 Diseases of liver
0.000 0.879 0.121
F60.5 Anankastic personality disorder
0.000 0.881 0.118
F53.0 Mild mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.000 0.884 0.115
F53.9 Puerperal mental disorder, unspecified
0.000 0.885 0.115
F53.8 Other mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.000 0.885 0.115
F53.1 Severe mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.000 0.885 0.115
F51.4 Sleep terrors [night terrors]
0.000 0.888 0.112
K70.9 Alcoholic liver disease, unspecified
0.000 0.893 0.107
K71 Toxic liver disease
0.000 0.895 0.105
K73 Chronic hepatitis, not elsewhere classified
0.000 0.895 0.105
F51.9 Nonorganic sleep disorder, unspecified
0.000 0.897 0.103
F51.8 Other nonorganic sleep disorders
0.000 0.897 0.103
F51.2 Nonorganic disorder of the sleep-wake schedule
0.000 0.897 0.103
F51.1 Nonorganic hypersomnia
0.000 0.897 0.103
K74 Fibrosis and cirrhosis of liver
0.000 0.897 0.103
F52 Sexual dysfunction, not caused by organic disorder or disease
0.000 0.898 0.102
K70.1 Alcoholic hepatitis
0.000 0.899 0.101
F51.5 Nightmares
0.000 0.900 0.100
K72 Hepatic failure, not elsewhere classified
0.000 0.901 0.099
K75 Other inflammatory liver diseases
0.000 0.903 0.097
F51.0 Nonorganic insomnia
0.000 0.905 0.095
F50.9 Eating disorder, unspecified
0.000 0.907 0.092
K72.9 Hepatic failure, unspecified
0.000 0.910 0.090
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.000 0.910 0.090
K74.6 Other and unspecified cirrhosis of liver
0.000 0.911 0.089
K75.0 Abscess of liver
0.000 0.911 0.089
F50.8 Other eating disorders
0.000 0.911 0.089
F50.5 Vomiting associated with other psychological disturbances
0.000 0.911 0.089
F50.4 Overeating associated with other psychological disturbances
0.000 0.911 0.089
F50.3 Atypical bulimia nervosa
0.000 0.911 0.089
F50.1 Atypical anorexia nervosa
0.000 0.911 0.089
F51.3 Sleepwalking [somnambulism]
0.001 0.913 0.087
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.913 0.087
K73.9 Chronic hepatitis, unspecified
0.000 0.917 0.083
K77 Liver disorders in diseases classified elsewhere
0.000 0.917 0.083
K71.0 Toxic liver disease with cholestasis
0.000 0.918 0.082
K75.9 Inflammatory liver disease, unspecified
0.000 0.919 0.081
K74.3 Primary biliary cirrhosis
0.000 0.920 0.080
K74.5 Biliary cirrhosis, unspecified
0.000 0.921 0.079
K74.1 Hepatic sclerosis
0.000 0.921 0.079
K76 Other diseases of liver
0.000 0.922 0.078
K71.1 Toxic liver disease with hepatic necrosis
0.000 0.922 0.078
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.922 0.078
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.924 0.076
K71.8 Toxic liver disease with other disorders of liver
0.000 0.925 0.075
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.925 0.075
K71.5 Toxic liver disease with chronic active hepatitis
0.000 0.925 0.075
K71.4 Toxic liver disease with chronic lobular hepatitis
0.000 0.925 0.075
K71.3 Toxic liver disease with chronic persistent hepatitis
0.000 0.925 0.075
K71.2 Toxic liver disease with acute hepatitis
0.000 0.925 0.075
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.925 0.075
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.925 0.075
K74.4 Secondary biliary cirrhosis
0.000 0.926 0.074
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.926 0.074
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease
0.000 0.926 0.073
F52.8 Other sexual dysfunction, not caused by organic disorder or disease
0.000 0.926 0.073
F52.7 Excessive sexual drive
0.000 0.926 0.073
F52.6 Nonorganic dyspareunia
0.000 0.926 0.073
F52.5 Nonorganic vaginismus
0.000 0.926 0.073
F52.4 Premature ejaculation
0.000 0.926 0.073
F52.3 Orgasmic dysfunction
0.000 0.926 0.073
F52.1 Sexual aversion and lack of sexual enjoyment
0.000 0.926 0.073
F50.0 Anorexia nervosa
0.001 0.927 0.073
K71.9 Toxic liver disease, unspecified
0.000 0.927 0.073
K76.9 Liver disease, unspecified
0.000 0.928 0.072
K75.2 Nonspecific reactive hepatitis
0.000 0.930 0.070
K75.1 Phlebitis of portal vein
0.000 0.930 0.070
F50.2 Bulimia nervosa
0.001 0.931 0.069
K72.1 Chronic hepatic failure
0.000 0.932 0.068
F40-F48 Neurotic, stress-related and somatoform disorders
0.000 0.933 0.067
F52.0 Lack or loss of sexual desire
0.001 0.934 0.066
K76.1 Chronic passive congestion of liver
0.000 0.936 0.064
K75.8 Other specified inflammatory liver diseases
0.000 0.936 0.064
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.940 0.060
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.941 0.059
K72.0 Acute and subacute hepatic failure
0.000 0.941 0.058
K76.5 Hepatic veno-occlusive disease
0.000 0.944 0.056
K76.4 Peliosis hepatis
0.000 0.944 0.056
K76.2 Central haemorrhagic necrosis of liver
0.000 0.944 0.056
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.944 0.056
K76.3 Infarction of liver
0.000 0.944 0.056
K70.0 Alcoholic fatty liver
0.000 0.944 0.055
K76.7 Hepatorenal syndrome
0.000 0.946 0.054
K74.0 Hepatic fibrosis
0.000 0.950 0.050
K76.6 Portal hypertension
0.000 0.952 0.048
K76.8 Other specified diseases of liver
0.000 0.953 0.047
F40 Phobic anxiety disorders
0.000 0.953 0.047
F48 Other neurotic disorders
0.000 0.955 0.045
F44 Dissociative [conversion] disorders
0.000 0.957 0.043
F42 Obsessive-compulsive disorder
0.000 0.959 0.041
F40.0 Agoraphobia
0.000 0.960 0.040
K75.4 Autoimmune hepatitis
0.000 0.963 0.037
F45 Somatoform disorders
0.000 0.964 0.036
F44.9 Dissociative [conversion] disorder, unspecified
0.000 0.965 0.034
F40.8 Other phobic anxiety disorders
0.000 0.966 0.034
F44.0 Dissociative amnesia
0.000 0.967 0.033
F48.0 Neurasthenia
0.000 0.967 0.033
F40.9 Phobic anxiety disorder, unspecified
0.000 0.967 0.033
F48.8 Other specified neurotic disorders
0.000 0.967 0.032
F48.1 Depersonalisation-derealisation syndrome
0.000 0.967 0.032
F42.2 Mixed obsessional thoughts and acts
0.000 0.967 0.032
F42.1 Predominantly compulsive acts [obsessional rituals]
0.000 0.968 0.032
F40.1 Social phobias
0.000 0.968 0.032
F41 Other anxiety disorders
0.000 0.968 0.032

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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