TreeWAS – Variant ID: rs28421666

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.000	0.339	0.661
D12.2 Ascending colon	0.000	0.341	0.659
D12.4 Descending colon	0.000	0.348	0.652
D12.3 Transverse colon	0.000	0.351	0.649
D12.0 Caecum	0.000	0.445	0.555
D12.8 Rectum	0.000	0.478	0.522
D12.7 Rectosigmoid junction	0.000	0.512	0.488
D12.1 Appendix	0.000	0.526	0.474
D12.5 Sigmoid colon	0.000	0.551	0.449
D12.6 Colon, unspecified	0.000	0.561	0.439
D12.9 Anus and anal canal	0.000	0.602	0.398
K90.0 Coeliac disease	0.000	0.806	0.194
K90 Intestinal malabsorption	0.007	0.907	0.086
K74.3 Primary biliary cirrhosis	0.088	0.912	0.000
K74 Fibrosis and cirrhosis of liver	0.082	0.918	0.000
I60-I69 Cerebrovascular diseases	0.081	0.919	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.921	0.079
I69 Sequelae of cerebrovascular disease	0.076	0.924	0.000
M06.9 Rheumatoid arthritis, unspecified	0.002	0.926	0.072
I64 Stroke, not specified as haemorrhage or infarction	0.074	0.926	0.000
I63 Cerebral infarction	0.073	0.927	0.000
I60 Subarachnoid haemorrhage	0.072	0.928	0.000
I62 Other nontraumatic intracranial haemorrhage	0.070	0.930	0.000
K74.5 Biliary cirrhosis, unspecified	0.069	0.931	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.931	0.068
K70-K77 Diseases of liver	0.068	0.932	0.000
K90.8 Other intestinal malabsorption	0.005	0.933	0.062
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.005	0.933	0.062
K90.3 Pancreatic steatorrhoea	0.005	0.933	0.062
K90.2 Blind loop syndrome, not elsewhere classified	0.005	0.933	0.062
K90.1 Tropical sprue	0.005	0.933	0.062
I69.1 Sequelae of intracerebral haemorrhage	0.066	0.934	0.000
K74.6 Other and unspecified cirrhosis of liver	0.066	0.934	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.066	0.934	0.000
I61 Intracerebral haemorrhage	0.066	0.934	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.065	0.935	0.000
I69.3 Sequelae of cerebral infarction	0.064	0.936	0.000
K76 Other diseases of liver	0.064	0.936	0.000
I67 Other cerebrovascular diseases	0.063	0.937	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.063	0.937	0.000
K90.9 Intestinal malabsorption, unspecified	0.005	0.937	0.058
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.062	0.938	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.061	0.939	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.061	0.939	0.000
I63.9 Cerebral infarction, unspecified	0.061	0.939	0.000
K76.8 Other specified diseases of liver	0.060	0.940	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.060	0.940	0.000
I60.8 Other subarachnoid haemorrhage	0.059	0.941	0.000
S90-S99 Injuries to the ankle and foot	0.059	0.941	0.000
K74.4 Secondary biliary cirrhosis	0.059	0.941	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.059	0.941	0.000
K74.1 Hepatic sclerosis	0.059	0.941	0.000
K74.0 Hepatic fibrosis	0.059	0.941	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.059	0.941	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.058	0.941	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.058	0.941	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.058	0.942	0.000
S70-S79 Injuries to the hip and thigh	0.058	0.942	0.000
T43.2 Other and unspecified antidepressants	0.057	0.942	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.057	0.943	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.057	0.943	0.000
M06 Other rheumatoid arthritis	0.008	0.943	0.048
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.057	0.943	0.000
Chapter IX Diseases of the circulatory system	0.056	0.944	0.000
I63.8 Other cerebral infarction	0.055	0.945	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.055	0.945	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.055	0.945	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.055	0.945	0.000
K70 Alcoholic liver disease	0.055	0.945	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.054	0.946	0.000
S50-S59 Injuries to the elbow and forearm	0.054	0.946	0.000
T39.1 4-Aminophenol derivatives	0.054	0.946	0.000
I67.8 Other specified cerebrovascular diseases	0.053	0.947	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.001	0.947	0.052
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.001	0.947	0.052
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.001	0.947	0.052
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.001	0.947	0.052
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.001	0.947	0.052
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.001	0.947	0.052
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.001	0.947	0.052
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.001	0.947	0.052
S72 Fracture of femur	0.053	0.947	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.053	0.947	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.052	0.947	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.052	0.947	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.052	0.947	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.052	0.947	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.052	0.947	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.052	0.948	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.052	0.948	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.052	0.948	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.052	0.948	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.052	0.948	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.052	0.948	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.052	0.948	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.052	0.948	0.000
S91 Open wound of ankle and foot	0.051	0.949	0.000
S10-S19 Injuries to the neck	0.051	0.949	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.051	0.949	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.050	0.950	0.000
I62.1 Nontraumatic extradural haemorrhage	0.050	0.950	0.000
S92 Fracture of foot, except ankle	0.050	0.950	0.000
I67.9 Cerebrovascular disease, unspecified	0.050	0.950	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.050	0.950	0.000
T93 Sequelae of injuries of lower limb	0.050	0.950	0.000
M05-M14 Inflammatory polyarthropathies	0.018	0.950	0.032
T92 Sequelae of injuries of upper limb	0.050	0.950	0.000
K76.9 Liver disease, unspecified	0.050	0.950	0.000
T90 Sequelae of injuries of head	0.049	0.950	0.000
T66-T78 Other and unspecified effects of external causes	0.049	0.951	0.000
K77 Liver disorders in diseases classified elsewhere	0.049	0.951	0.000
K73 Chronic hepatitis, not elsewhere classified	0.049	0.951	0.000
K71 Toxic liver disease	0.049	0.951	0.000
K72 Hepatic failure, not elsewhere classified	0.049	0.951	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.049	0.951	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.048	0.952	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.048	0.952	0.000
I05-I09 Chronic rheumatic heart diseases	0.048	0.952	0.000
M25 Other joint disorders, not elsewhere classified	0.048	0.952	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.048	0.952	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.048	0.952	0.000
S51 Open wound of forearm	0.048	0.952	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.047	0.952	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.047	0.952	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.047	0.952	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.047	0.952	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.047	0.952	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.047	0.952	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.047	0.952	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.047	0.952	0.000
T36 Poisoning by systemic antibiotics	0.047	0.952	0.000
S40-S49 Injuries to the shoulder and upper arm	0.047	0.952	0.000
I61.8 Other intracerebral haemorrhage	0.047	0.953	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.047	0.953	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.047	0.953	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.047	0.953	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.047	0.953	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.047	0.953	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.047	0.953	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.047	0.953	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.047	0.953	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.047	0.953	0.000
T79-T79 Certain early complications of trauma	0.047	0.953	0.000
T33-T35 Frostbite	0.047	0.953	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.047	0.953	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.047	0.953	0.000
T00-T07 Injuries involving multiple body regions	0.047	0.953	0.000
# Top node	0.047	0.953	0.000
M20-M25 Other joint disorders	0.047	0.953	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.046	0.954	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.046	0.954	0.000
Chapter VIII Diseases of the ear and mastoid process	0.046	0.954	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.046	0.954	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.046	0.954	0.000
K76.7 Hepatorenal syndrome	0.046	0.954	0.000
K76.5 Hepatic veno-occlusive disease	0.046	0.954	0.000
K76.4 Peliosis hepatis	0.046	0.954	0.000
K76.3 Infarction of liver	0.046	0.954	0.000
K76.2 Central haemorrhagic necrosis of liver	0.046	0.954	0.000
K76.1 Chronic passive congestion of liver	0.046	0.954	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.046	0.954	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.046	0.954	0.000
I67.5 Moyamoya disease	0.046	0.954	0.000
I67.4 Hypertensive encephalopathy	0.046	0.954	0.000
I67.3 Progressive vascular leukoencephalopathy	0.046	0.954	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.046	0.954	0.000
S72.3 Fracture of shaft of femur	0.046	0.954	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.045	0.954	0.000
S91.3 Open wound of other parts of foot	0.046	0.954	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.045	0.954	0.000
M25.5 Pain in joint	0.045	0.955	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.045	0.955	0.000
M23 Internal derangement of knee	0.045	0.955	0.000
S20-S29 Injuries to the thorax	0.045	0.955	0.000
K70.4 Alcoholic hepatic failure	0.045	0.955	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.045	0.955	0.000
K75 Other inflammatory liver diseases	0.045	0.955	0.000
M23.3 Other meniscus derangements	0.045	0.955	0.000
H65-H75 Diseases of middle ear and mastoid	0.045	0.955	0.000
M25.56 Pain in joint (Lower leg)	0.045	0.955	0.000
T43.9 Psychotropic drug, unspecified	0.044	0.956	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.044	0.956	0.000
T43.6 Psychostimulants with abuse potential	0.044	0.956	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.044	0.956	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.044	0.956	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.044	0.956	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.044	0.956	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.044	0.956	0.000
T39.4 Antirheumatics, not elsewhere classified	0.044	0.956	0.000
T39.2 Pyrazolone derivatives	0.044	0.956	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.044	0.956	0.000
I27 Other pulmonary heart diseases	0.043	0.957	0.000
T98 Sequelae of other and unspecified effects of external causes	0.043	0.957	0.000
T95 Sequelae of burns, corrosions and frostbite	0.043	0.957	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.043	0.957	0.000
T91 Sequelae of injuries of neck and trunk	0.043	0.957	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.043	0.957	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.043	0.957	0.000
S79 Other and unspecified injuries of hip and thigh	0.043	0.957	0.000
S90 Superficial injury of ankle and foot	0.043	0.957	0.000
T93.2 Sequelae of other fractures of lower limb	0.043	0.957	0.000
S99 Other and unspecified injuries of ankle and foot	0.043	0.957	0.000
S98 Traumatic amputation of ankle and foot	0.043	0.957	0.000
S97 Crushing injury of ankle and foot	0.043	0.957	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.043	0.957	0.000
S95 Injury of blood vessels at ankle and foot level	0.043	0.957	0.000
S94 Injury of nerves at ankle and foot level	0.043	0.957	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.043	0.957	0.000
K76.6 Portal hypertension	0.042	0.958	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.042	0.958	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.042	0.958	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.042	0.958	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.042	0.958	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.042	0.958	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.042	0.958	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.042	0.958	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.042	0.958	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.042	0.958	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.042	0.958	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.042	0.958	0.000
I68.0 Cerebral amyloid angiopathy	0.042	0.958	0.000
S72.0 Fracture of neck of femur	0.042	0.958	0.000
I05 Rheumatic mitral valve diseases	0.042	0.958	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.042	0.958	0.000
I67.1 Cerebral aneurysm, nonruptured	0.042	0.958	0.000
K70.1 Alcoholic hepatitis	0.042	0.958	0.000
S72.1 Pertrochanteric fracture	0.042	0.958	0.000
S78 Traumatic amputation of hip and thigh	0.042	0.958	0.000
S77 Crushing injury of hip and thigh	0.042	0.958	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.042	0.958	0.000
S75 Injury of blood vessels at hip and thigh level	0.042	0.958	0.000
S74 Injury of nerves at hip and thigh level	0.042	0.958	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.042	0.958	0.000
S71 Open wound of hip and thigh	0.042	0.958	0.000
S92.3 Fracture of metatarsal bone	0.042	0.958	0.000
S51.9 Open wound of forearm, part unspecified	0.041	0.958	0.000
H66 Suppurative and unspecified otitis media	0.042	0.958	0.000
T17 Foreign body in respiratory tract	0.041	0.958	0.000
Chapter VI Diseases of the nervous system	0.041	0.959	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.041	0.959	0.000
I27.2 Other secondary pulmonary hypertension	0.041	0.959	0.000
K70.3 Alcoholic cirrhosis of liver	0.041	0.959	0.000
S72.4 Fracture of lower end of femur	0.041	0.959	0.000
T18 Foreign body in alimentary tract	0.041	0.959	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.041	0.959	0.000
S37 Injury of urinary and pelvic organs	0.041	0.959	0.000
S36 Injury of intra-abdominal organs	0.041	0.959	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.041	0.959	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.041	0.959	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.041	0.959	0.000
S31 Open wound of abdomen, lower back and pelvis	0.041	0.959	0.000
M06.8 Other specified rheumatoid arthritis	0.006	0.959	0.035
M06.4 Inflammatory polyarthropathy	0.006	0.959	0.035
M06.3 Rheumatoid nodule	0.006	0.959	0.035
M06.2 Rheumatoid bursitis	0.006	0.959	0.035
M06.1 Adult-onset Still's disease	0.006	0.959	0.035
M25.4 Effusion of joint	0.041	0.959	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.041	0.959	0.000
T39.0 Salicylates	0.041	0.959	0.000
H60-H62 Diseases of external ear	0.041	0.959	0.000
S50 Superficial injury of forearm	0.040	0.959	0.000
I00-I02 Acute rheumatic fever	0.040	0.959	0.000
S72.30 Fracture of shaft of femur (closed)	0.040	0.960	0.000
T42.4 Benzodiazepines	0.040	0.960	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.040	0.960	0.000
M06.0 Seronegative rheumatoid arthritis	0.006	0.960	0.034
Q20-Q28 Congenital malformations of the circulatory system	0.040	0.960	0.000
M25.8 Other specified joint disorders	0.040	0.960	0.000
M25.57 Pain in joint (Ankle and foot)	0.040	0.960	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.040	0.960	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.040	0.960	0.000
S51.8 Open wound of other parts of forearm	0.039	0.961	0.000
S92.0 Fracture of calcaneus	0.039	0.961	0.000
S70 Superficial injury of hip and thigh	0.039	0.961	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.039	0.961	0.000
K70.0 Alcoholic fatty liver	0.039	0.961	0.000
T92.1 Sequelae of fracture of arm	0.039	0.961	0.000
M23.5 Chronic instability of knee	0.039	0.961	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.039	0.961	0.000
I67.2 Cerebral atherosclerosis	0.039	0.961	0.000
S59 Other and unspecified injuries of forearm	0.039	0.961	0.000
S58 Traumatic amputation of forearm	0.039	0.961	0.000
S57 Crushing injury of forearm	0.039	0.961	0.000
S56 Injury of muscle and tendon at forearm level	0.039	0.961	0.000
S55 Injury of blood vessels at forearm level	0.039	0.961	0.000
S54 Injury of nerves at forearm level	0.039	0.961	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.039	0.961	0.000
O48 Prolonged pregnancy	0.039	0.961	0.000
S12 Fracture of neck	0.038	0.961	0.000
S72.9 Fracture of femur, part unspecified	0.038	0.962	0.000
S72.8 Fractures of other parts of femur	0.038	0.962	0.000
S72.7 Multiple fractures of femur	0.038	0.962	0.000
S72.2 Subtrochanteric fracture	0.038	0.962	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.038	0.962	0.000
M34 Systemic sclerosis	0.038	0.962	0.000
T78 Adverse effects, not elsewhere classified	0.038	0.962	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.038	0.962	0.000
T19 Foreign body in genito-urinary tract	0.038	0.962	0.000
T15 Foreign body on external eye	0.038	0.962	0.000
T16 Foreign body in ear	0.038	0.962	0.000
I72 Other aneurysm	0.038	0.962	0.000
M13 Other arthritis	0.008	0.962	0.030
H66.3 Other chronic suppurative otitis media	0.038	0.962	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.038	0.962	0.000
S32 Fracture of lumbar spine and pelvis	0.038	0.962	0.000
I70 Atherosclerosis	0.037	0.963	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.037	0.963	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.037	0.963	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.037	0.963	0.000
I65.1 Occlusion and stenosis of basilar artery	0.037	0.963	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.037	0.963	0.000
M25.7 Osteophyte	0.037	0.963	0.000
I74 Arterial embolism and thrombosis	0.037	0.963	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.037	0.963	0.000
H72 Perforation of tympanic membrane	0.037	0.963	0.000
S91.7 Multiple open wounds of ankle and foot	0.037	0.963	0.000
S91.2 Open wound of toe(s) with damage to nail	0.037	0.963	0.000
S91.1 Open wound of toe(s) without damage to nail	0.037	0.963	0.000
S91.0 Open wound of ankle	0.037	0.963	0.000
O47 False labour	0.037	0.963	0.000
S19 Other and unspecified injuries of neck	0.037	0.963	0.000
S17 Crushing injury of neck	0.037	0.963	0.000
S15 Injury of blood vessels at neck level	0.037	0.963	0.000
S14 Injury of nerves and spinal cord at neck level	0.037	0.963	0.000
S11 Open wound of neck	0.037	0.963	0.000
S10 Superficial injury of neck	0.037	0.963	0.000
S18 Traumatic amputation at neck level	0.037	0.963	0.000
S16 Injury of muscle and tendon at neck level	0.037	0.963	0.000
S80-S89 Injuries to the knee and lower leg	0.037	0.963	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.037	0.963	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.036	0.963	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.036	0.963	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.036	0.963	0.000
T42.3 Barbiturates	0.036	0.963	0.000
T42.2 Succinimides and oxazolidinediones	0.036	0.963	0.000
T42.1 Iminostilbenes	0.036	0.963	0.000
T42.0 Hydantoin derivatives	0.036	0.963	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.036	0.963	0.000
Q80-Q89 Other congenital malformations	0.036	0.963	0.000
G20-G26 Extrapyramidal and movement disorders	0.036	0.964	0.000
I08 Multiple valve diseases	0.036	0.964	0.000
M50-M54 Other dorsopathies	0.036	0.964	0.000
S92.9 Fracture of foot, unspecified	0.036	0.964	0.000
S92.7 Multiple fractures of foot	0.036	0.964	0.000
S92.5 Fracture of other toe	0.036	0.964	0.000
S92.4 Fracture of great toe	0.036	0.964	0.000
S92.2 Fracture of other tarsal bone(s)	0.036	0.964	0.000
S92.1 Fracture of talus	0.036	0.964	0.000
O40 Polyhydramnios	0.036	0.964	0.000
H74 Other disorders of middle ear and mastoid	0.036	0.964	0.000
K90-K93 Other diseases of the digestive system	0.016	0.964	0.020
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.036	0.964	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.036	0.964	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.036	0.964	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.036	0.964	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.036	0.964	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.036	0.964	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.036	0.964	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.036	0.964	0.000
T44.0 Anticholinesterase agents	0.036	0.964	0.000
M25.46 Effusion of joint (Lower leg)	0.036	0.964	0.000
S20 Superficial injury of thorax	0.036	0.964	0.000
M11 Other crystal arthropathies	0.012	0.964	0.024
O46 Antepartum haemorrhage, not elsewhere classified	0.036	0.964	0.000
O42 Premature rupture of membranes	0.036	0.964	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.036	0.964	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.036	0.964	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.036	0.964	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.036	0.964	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.036	0.964	0.000
T93.1 Sequelae of fracture of femur	0.036	0.964	0.000
T93.0 Sequelae of open wound of lower limb	0.036	0.964	0.000
M14 Arthropathies in other diseases classified elsewhere	0.013	0.964	0.023
M12 Other specific arthropathies	0.013	0.964	0.023
M09 Juvenile arthritis in diseases classified elsewhere	0.013	0.964	0.023
M08 Juvenile arthritis	0.013	0.964	0.023
M05 Seropositive rheumatoid arthritis	0.013	0.964	0.023
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.036	0.964	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.036	0.964	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.036	0.964	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.036	0.964	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.036	0.964	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.036	0.964	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.036	0.964	0.000
T92.0 Sequelae of open wound of upper limb	0.036	0.964	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.036	0.964	0.000
T90.9 Sequelae of unspecified injury of head	0.036	0.964	0.000
T90.8 Sequelae of other specified injuries of head	0.036	0.964	0.000
T90.5 Sequelae of intracranial injury	0.036	0.964	0.000
T90.4 Sequelae of injury of eye and orbit	0.036	0.964	0.000
T90.3 Sequelae of injury of cranial nerves	0.036	0.964	0.000
T90.1 Sequelae of open wound of head	0.036	0.964	0.000
T90.0 Sequelae of superficial injury of head	0.036	0.964	0.000
O80-O84 Delivery	0.036	0.964	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.036	0.964	0.000
I05.9 Mitral valve disease, unspecified	0.036	0.964	0.000
M35 Other systemic involvement of connective tissue	0.036	0.964	0.000
S92.30 Fracture of metatarsal bone (closed)	0.036	0.964	0.000
T75 Effects of other external causes	0.035	0.964	0.000
T74 Maltreatment syndromes	0.035	0.964	0.000
T73 Effects of other deprivation	0.035	0.964	0.000
T70 Effects of air pressure and water pressure	0.035	0.964	0.000
T69 Other effects of reduced temperature	0.035	0.964	0.000
T67 Effects of heat and light	0.035	0.964	0.000
T71 Asphyxiation	0.035	0.964	0.000
T68 Hypothermia	0.035	0.964	0.000
T66 Unspecified effects of radiation	0.035	0.964	0.000
K71.9 Toxic liver disease, unspecified	0.035	0.964	0.000
K71.8 Toxic liver disease with other disorders of liver	0.035	0.964	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.035	0.964	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.035	0.964	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.035	0.964	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.035	0.964	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.035	0.964	0.000
K71.2 Toxic liver disease with acute hepatitis	0.035	0.964	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.035	0.964	0.000
K71.0 Toxic liver disease with cholestasis	0.035	0.964	0.000
K73.9 Chronic hepatitis, unspecified	0.035	0.964	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.035	0.964	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.035	0.964	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.035	0.964	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.035	0.964	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.035	0.964	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.035	0.964	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.035	0.964	0.000
K72.1 Chronic hepatic failure	0.035	0.964	0.000
K72.0 Acute and subacute hepatic failure	0.035	0.964	0.000
G62 Other polyneuropathies	0.035	0.964	0.000
T31 Burns classified according to extent of body surface involved	0.035	0.964	0.000
K72.9 Hepatic failure, unspecified	0.035	0.965	0.000
M07 Psoriatic and enteropathic arthropathies	0.013	0.965	0.023
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.035	0.965	0.000
H61 Other disorders of external ear	0.035	0.965	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.035	0.965	0.000
Q50-Q56 Congenital malformations of genital organs	0.035	0.965	0.000
Q60-Q64 Congenital malformations of the urinary system	0.035	0.965	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.035	0.965	0.000
T40.2 Other opioids	0.035	0.965	0.000
M31 Other necrotising vasculopathies	0.035	0.965	0.000
J30-J39 Other diseases of upper respiratory tract	0.035	0.965	0.000
M25.51 Pain in joint (Shoulder region)	0.035	0.965	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.035	0.965	0.000
I28 Other diseases of pulmonary vessels	0.035	0.965	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.035	0.965	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.035	0.965	0.000
S30.2 Contusion of external genital organs	0.035	0.965	0.000
S30.1 Contusion of abdominal wall	0.035	0.965	0.000
S30.0 Contusion of lower back and pelvis	0.035	0.965	0.000
I09 Other rheumatic heart diseases	0.035	0.965	0.000
I06 Rheumatic aortic valve diseases	0.035	0.965	0.000
I84 Haemorrhoids	0.035	0.965	0.000
M25.9 Joint disorder, unspecified	0.035	0.965	0.000
M25.3 Other instability of joint	0.035	0.965	0.000
M25.2 Flail joint	0.035	0.965	0.000
M25.1 Fistula of joint	0.035	0.965	0.000
M25.0 Haemarthrosis	0.035	0.965	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.034	0.965	0.000
T40.8 Lysergide [LSD]	0.034	0.965	0.000
T40.7 Cannabis (derivatives)	0.034	0.965	0.000
T40.6 Other and unspecified narcotics	0.034	0.965	0.000
T40.5 Cocaine	0.034	0.965	0.000
T40.4 Other synthetic narcotics	0.034	0.965	0.000
T40.3 Methadone	0.034	0.965	0.000
T40.1 Heroin	0.034	0.965	0.000
T40.0 Opium	0.034	0.965	0.000
I07 Rheumatic tricuspid valve diseases	0.035	0.965	0.000
Chapter XXII Codes for special purposes	0.035	0.965	0.000
M24 Other specific joint derangements	0.035	0.965	0.000
T32 Corrosions classified according to extent of body surface involved	0.034	0.965	0.000
T30 Burn and corrosion, body region unspecified	0.034	0.965	0.000
T29 Burns and corrosions of multiple body regions	0.034	0.965	0.000
S51.7 Multiple open wounds of forearm	0.034	0.966	0.000
H66.9 Otitis media, unspecified	0.034	0.966	0.000
J32.9 Chronic sinusitis, unspecified	0.034	0.966	0.000
T36.9 Systemic antibiotic, unspecified	0.034	0.966	0.000
T36.8 Other systemic antibiotics	0.034	0.966	0.000
T36.7 Antifungal antibiotics, systemically used	0.034	0.966	0.000
T36.6 Rifamycins	0.034	0.966	0.000
T36.5 Aminoglycosides	0.034	0.966	0.000
T36.4 Tetracyclines	0.034	0.966	0.000
T36.3 Macrolides	0.034	0.966	0.000
T36.2 Chloramphenicol group	0.034	0.966	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.034	0.966	0.000
T36.0 Penicillins	0.034	0.966	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.034	0.966	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.034	0.966	0.000
T37.5 Antiviral drugs	0.034	0.966	0.000
T37.4 Anthelminthics	0.034	0.966	0.000
T37.3 Other antiprotozoal drugs	0.034	0.966	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.034	0.966	0.000
T37.1 Antimycobacterial drugs	0.034	0.966	0.000
T37.0 Sulphonamides	0.034	0.966	0.000
T38.9 Other and unspecified hormone antagonists	0.034	0.966	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.034	0.966	0.000
T38.7 Androgens and anabolic congeners	0.034	0.966	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.034	0.966	0.000
T38.5 Other oestrogens and progestogens	0.034	0.966	0.000
T38.4 Oral contraceptives	0.034	0.966	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.034	0.966	0.000
T38.2 Antithyroid drugs	0.034	0.966	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations