TreeWAS – Variant ID: rs2842385

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O20 Haemorrhage in early pregnancy	0.000	0.378	0.622
O20.0 Threatened abortion	0.000	0.383	0.617
O20-O29 Other maternal disorders predominantly related to pregnancy	0.000	0.389	0.611
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.416	0.584
O26 Maternal care for other conditions predominantly related to pregnancy	0.000	0.419	0.581
O24 Diabetes mellitus in pregnancy	0.000	0.426	0.574
O26.8 Other specified pregnancy-related conditions	0.000	0.433	0.567
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.442	0.558
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.450	0.550
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.455	0.545
Chapter XV Pregnancy, childbirth and the puerperium	0.000	0.468	0.532
O16 Unspecified maternal hypertension	0.000	0.469	0.531
O20.8 Other haemorrhage in early pregnancy	0.000	0.475	0.525
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.480	0.520
O14.9 Preeclampsia, unspecified	0.000	0.483	0.517
O14.0 Moderate preeclampsia	0.000	0.492	0.508
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.000	0.512	0.488
O22 Venous complications in pregnancy	0.000	0.555	0.445
O14.1 Severe preeclampsia	0.000	0.557	0.443
O28 Abnormal findings on antenatal screening of mother	0.000	0.558	0.442
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.000	0.559	0.441
O29 Complications of anaesthesia during pregnancy	0.000	0.562	0.438
O25 Malnutrition in pregnancy	0.000	0.562	0.438
O26.5 Maternal hypotension syndrome	0.000	0.583	0.417
O26.4 Herpes gestationis	0.000	0.583	0.417
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.000	0.583	0.417
O26.1 Low weight gain in pregnancy	0.000	0.583	0.417
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.588	0.412
O24.3 Pre-existing diabetes mellitus, unspecified	0.000	0.588	0.411
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.000	0.588	0.411
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.000	0.588	0.411
O85-O92 Complications predominantly related to the puerperium	0.000	0.596	0.404
O26.0 Excessive weight gain in pregnancy	0.000	0.599	0.401
O15 Eclampsia	0.000	0.600	0.400
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.000	0.600	0.400
O14.2 HELLP syndrome	0.000	0.605	0.395
O24.9 Diabetes mellitus in pregnancy, unspecified	0.000	0.609	0.391
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.000	0.611	0.389
O94-O99 Other obstetric conditions, not elsewhere classified	0.000	0.616	0.384
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.000	0.629	0.371
O26.2 Pregnancy care of habitual aborter	0.000	0.638	0.361
O26.9 Pregnancy-related condition, unspecified	0.000	0.642	0.358
O85 Puerperal sepsis	0.000	0.660	0.340
O23 Infections of genito-urinary tract in pregnancy	0.000	0.663	0.337
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.000	0.664	0.336
O22.4 Haemorrhoids in pregnancy	0.000	0.673	0.326
O92 Other disorders of breast and lactation associated with childbirth	0.000	0.674	0.326
O22.9 Venous complication in pregnancy, unspecified	0.000	0.681	0.319
O22.8 Other venous complications in pregnancy	0.000	0.681	0.319
O22.5 Cerebral venous thrombosis in pregnancy	0.000	0.681	0.319
O22.3 Deep phlebothrombosis in pregnancy	0.000	0.681	0.319
O22.2 Superficial thrombophlebitis in pregnancy	0.000	0.681	0.319
O22.1 Genital varices in pregnancy	0.000	0.681	0.319
O22.0 Varicose veins of lower extremity in pregnancy	0.000	0.681	0.319
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.000	0.683	0.317
O28.8 Other abnormal findings on antenatal screening of mother	0.000	0.683	0.317
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.000	0.683	0.317
O28.4 Abnormal radiological finding on antenatal screening of mother	0.000	0.683	0.317
O28.2 Abnormal cytological finding on antenatal screening of mother	0.000	0.683	0.317
O28.0 Abnormal haematological finding on antenatal screening of mother	0.000	0.683	0.317
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.000	0.686	0.314
O29.8 Other complications of anaesthesia during pregnancy	0.000	0.686	0.314
O29.6 Failed or difficult intubation during pregnancy	0.000	0.686	0.314
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.000	0.686	0.314
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.000	0.686	0.314
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.000	0.686	0.314
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.000	0.686	0.314
O29.1 Cardiac complications of anaesthesia during pregnancy	0.000	0.686	0.314
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.000	0.686	0.314
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.693	0.307
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.000	0.701	0.299
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.705	0.295
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.705	0.295
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.705	0.295
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.705	0.295
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.000	0.705	0.295
O89 Complications of anaesthesia during the puerperium	0.000	0.708	0.292
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.710	0.290
O91 Infections of breast associated with childbirth	0.000	0.710	0.290
O88 Obstetric embolism	0.000	0.710	0.290
O15.9 Eclampsia, unspecified as to time period	0.000	0.713	0.287
O15.2 Eclampsia in the puerperium	0.000	0.713	0.287
O15.1 Eclampsia in labour	0.000	0.713	0.287
O15.0 Eclampsia in pregnancy	0.000	0.713	0.287
O12.1 Gestational proteinuria	0.000	0.714	0.286
O12.0 Gestational oedema	0.000	0.724	0.276
O97 Death from sequelae of direct obstetric causes	0.000	0.724	0.275
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.000	0.724	0.275
O95 Obstetric death of unspecified cause	0.000	0.724	0.275
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.000	0.724	0.275
O92.2 Other and unspecified disorders of breast associated with childbirth	0.000	0.725	0.275
O90 Complications of the puerperium, not elsewhere classified	0.000	0.733	0.267
O21 Excessive vomiting in pregnancy	0.000	0.734	0.265
O12.2 Gestational oedema with proteinuria	0.000	0.737	0.263
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.739	0.261
O00-O08 Pregnancy with abortive outcome	0.000	0.742	0.258
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.000	0.742	0.258
O87 Venous complications in the puerperium	0.000	0.742	0.258
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.746	0.254
O86 Other puerperal infections	0.000	0.756	0.244
O23.3 Infections of other parts of urinary tract in pregnancy	0.000	0.758	0.242
O23.2 Infections of urethra in pregnancy	0.000	0.758	0.242
O23.1 Infections of bladder in pregnancy	0.000	0.758	0.242
O23.0 Infections of kidney in pregnancy	0.000	0.758	0.242
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.763	0.237
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.763	0.237
O92.7 Other and unspecified disorders of lactation	0.000	0.766	0.234
O92.6 Galactorrhoea	0.000	0.766	0.234
O92.5 Suppressed lactation	0.000	0.766	0.234
O92.4 Hypogalactia	0.000	0.766	0.234
O92.3 Agalactia	0.000	0.766	0.234
O92.0 Retracted nipple associated with childbirth	0.000	0.766	0.234
O92.1 Cracked nipple associated with childbirth	0.000	0.775	0.224
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.775	0.225
O03 Spontaneous abortion	0.000	0.787	0.213
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.000	0.788	0.212
O23.4 Unspecified infection of urinary tract in pregnancy	0.000	0.788	0.212
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.000	0.790	0.209
O89.8 Other complications of anaesthesia during the puerperium	0.000	0.790	0.209
O89.6 Failed or difficult intubation during the puerperium	0.000	0.790	0.209
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.000	0.790	0.209
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.000	0.790	0.209
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.000	0.790	0.209
O89.1 Cardiac complications of anaesthesia during the puerperium	0.000	0.790	0.209
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.000	0.790	0.209
O88.8 Other obstetric embolism	0.000	0.792	0.208
O88.3 Obstetric pyaemic and septic embolism	0.000	0.792	0.208
O88.2 Obstetric blood-clot embolism	0.000	0.792	0.208
O88.1 Amniotic fluid embolism	0.000	0.792	0.208
O88.0 Obstetric air embolism	0.000	0.792	0.208
O91.2 Nonpurulent mastitis associated with childbirth	0.000	0.792	0.208
O91.1 Abscess of breast associated with childbirth	0.000	0.792	0.208
O91.0 Infection of nipple associated with childbirth	0.000	0.792	0.208
O90.8 Other complications of the puerperium, not elsewhere classified	0.000	0.794	0.205
O96.9 Death from unspecified obstetric cause	0.000	0.802	0.198
O96.1 Death from indirect obstetric cause	0.000	0.802	0.198
O96.0 Death from direct obstetric cause	0.000	0.802	0.198
O97.9 Death from sequelae of obstetric cause, unspecified	0.000	0.802	0.198
O97.1 Death from sequelae of indirect obstetric cause	0.000	0.802	0.198
O97.0 Death from sequelae of direct obstetric cause	0.000	0.802	0.198
O21.8 Other vomiting complicating pregnancy	0.000	0.803	0.197
O03.9 Complete or unspecified, without complication	0.000	0.804	0.196
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.000	0.804	0.196
O00 Ectopic pregnancy	0.000	0.805	0.195
O80-O84 Delivery	0.000	0.805	0.195
O86.2 Urinary tract infection following delivery	0.000	0.806	0.194
O90.5 Postpartum thyroiditis	0.000	0.808	0.192
O90.4 Postpartum acute renal failure	0.000	0.808	0.192
O90.3 Cardiomyopathy in the puerperium	0.000	0.808	0.192
O90.2 Haematoma of obstetric wound	0.000	0.810	0.189
O21.0 Mild hyperemesis gravidarum	0.000	0.811	0.189
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.000	0.813	0.187
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.000	0.813	0.187
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.000	0.813	0.187
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.000	0.813	0.187
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.000	0.813	0.187
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.000	0.813	0.187
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.000	0.813	0.187
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.000	0.813	0.187
O90.9 Complication of the puerperium, unspecified	0.000	0.813	0.187
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.814	0.185
O07 Failed attempted abortion	0.000	0.814	0.185
O06 Unspecified abortion	0.000	0.814	0.185
O05 Other abortion	0.000	0.814	0.185
O01 Hydatidiform mole	0.000	0.814	0.185
O87.9 Venous complication in the puerperium, unspecified	0.000	0.815	0.185
O87.8 Other venous complications in the puerperium	0.000	0.815	0.185
O87.3 Cerebral venous thrombosis in the puerperium	0.000	0.815	0.185
O87.1 Deep phlebothrombosis in the puerperium	0.000	0.815	0.185
O87.0 Superficial thrombophlebitis in the puerperium	0.000	0.815	0.185
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.816	0.184
O90.0 Disruption of Caesarean section wound	0.000	0.819	0.181
O08 Complications following abortion and ectopic and molar pregnancy	0.000	0.819	0.181
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.820	0.180
O86.8 Other specified puerperal infections	0.000	0.825	0.175
O86.3 Other genito-urinary tract infections following delivery	0.000	0.825	0.175
O90.1 Disruption of perineal obstetric wound	0.000	0.828	0.172
O86.0 Infection of obstetric surgical wound	0.000	0.833	0.167
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.834	0.166
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.839	0.161
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.839	0.161
O21.2 Late vomiting of pregnancy	0.000	0.840	0.159
O60-O75 Complications of labour and delivery	0.000	0.840	0.160
O86.1 Other infection of genital tract following delivery	0.000	0.841	0.159
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.001	0.842	0.157
O23.5 Infections of the genital tract in pregnancy	0.001	0.843	0.157
O87.2 Haemorrhoids in the puerperium	0.000	0.847	0.153
O03.8 Complete or unspecified, with other and unspecified complications	0.000	0.847	0.153
O03.7 Complete or unspecified, complicated by embolism	0.000	0.847	0.153
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.000	0.847	0.153
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.000	0.847	0.153
O03.2 Incomplete, complicated by embolism	0.000	0.847	0.153
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.000	0.847	0.153
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.850	0.150
O00.9 Ectopic pregnancy, unspecified	0.000	0.853	0.147
O72 Postpartum haemorrhage	0.000	0.854	0.146
O82 Single delivery by Caesarean section	0.000	0.855	0.144
O00.1 Tubal pregnancy	0.000	0.856	0.144
O00.8 Other ectopic pregnancy	0.000	0.860	0.140
O00.2 Ovarian pregnancy	0.000	0.860	0.140
O00.0 Abdominal pregnancy	0.000	0.860	0.140
O84 Multiple delivery	0.000	0.860	0.140
O83 Other assisted single delivery	0.000	0.860	0.140
O69 Labour and delivery complicated by umbilical cord complications	0.000	0.861	0.139
O03.3 Incomplete, with other and unspecified complications	0.000	0.861	0.139
O73 Retained placenta and membranes, without haemorrhage	0.000	0.862	0.138
O72.2 Delayed and secondary postpartum haemorrhage	0.000	0.863	0.137
O75 Other complications of labour and delivery, not elsewhere classified	0.000	0.865	0.135
O21.9 Vomiting of pregnancy, unspecified	0.001	0.866	0.134
O01.9 Hydatidiform mole, unspecified	0.000	0.867	0.133
O01.1 Incomplete and partial hydatidiform mole	0.000	0.867	0.133
O01.0 Classical hydatidiform mole	0.000	0.867	0.133
O05.9 Complete or unspecified, without complication	0.000	0.867	0.133
O05.8 Complete or unspecified, with other and unspecified complications	0.000	0.867	0.133
O05.7 Complete or unspecified, complicated by embolism	0.000	0.867	0.133
O05.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.000	0.867	0.133
O05.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.000	0.867	0.133
O05.4 Incomplete, without complication	0.000	0.867	0.133
O05.3 Incomplete, with other and unspecified complications	0.000	0.867	0.133
O05.2 Incomplete, complicated by embolism	0.000	0.867	0.133
O05.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.867	0.133
O05.0 Incomplete, complicated by genital tract and pelvic infection	0.000	0.867	0.133
O06.9 Complete or unspecified, without complication	0.000	0.867	0.133
O06.8 Complete or unspecified, with other and unspecified complications	0.000	0.867	0.133
O06.7 Complete or unspecified, complicated by embolism	0.000	0.867	0.133
O06.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.000	0.867	0.133
O06.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.000	0.867	0.133
O06.4 Incomplete, without complication	0.000	0.867	0.133
O06.3 Incomplete, with other and unspecified complications	0.000	0.867	0.133
O06.2 Incomplete, complicated by embolism	0.000	0.867	0.133
O06.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.867	0.133
O06.0 Incomplete, complicated by genital tract and pelvic infection	0.000	0.867	0.133
O07.9 Other and unspecified failed attempted abortion, without complication	0.000	0.867	0.133
O07.8 Other and unspecified failed attempted abortion, with other and unspecified complications	0.000	0.867	0.133
O07.7 Other and unspecified failed attempted abortion, complicated by embolism	0.000	0.867	0.133
O07.6 Other and unspecified failed attempted abortion, complicated by delayed or excessive haemorrhage	0.000	0.867	0.133
O07.5 Other and unspecified failed attempted abortion, complicated by genital tract and pelvic infection	0.000	0.867	0.133
O07.4 Failed medical abortion, without complication	0.000	0.867	0.133
O07.3 Failed medical abortion, with other and unspecified complications	0.000	0.867	0.133
O07.2 Failed medical abortion, complicated by embolism	0.000	0.867	0.133
O07.1 Failed medical abortion, complicated by delayed or excessive haemorrhage	0.000	0.867	0.133
O07.0 Failed medical abortion, complicated by genital tract and pelvic infection	0.000	0.867	0.133
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.000	0.868	0.132
O08.9 Complication following abortion and ectopic and molar pregnancy, unspecified	0.000	0.870	0.130
O08.8 Other complications following abortion and ectopic and molar pregnancy	0.000	0.870	0.130
O08.7 Other venous complications following abortion and ectopic and molar pregnancy	0.000	0.870	0.130
O08.6 Damage to pelvic organs and tissues following abortion and ectopic and molar pregnancy	0.000	0.870	0.130
O08.5 Metabolic disorders following abortion and ectopic and molar pregnancy	0.000	0.870	0.130
O08.4 Renal failure following abortion and ectopic and molar pregnancy	0.000	0.870	0.130
O08.3 Shock following abortion and ectopic and molar pregnancy	0.000	0.870	0.130
O08.2 Embolism following abortion and ectopic and molar pregnancy	0.000	0.870	0.130
O08.0 Genital tract and pelvic infection following abortion and ectopic and molar pregnancy	0.000	0.870	0.130
O86.4 Pyrexia of unknown origin following delivery	0.000	0.871	0.129
O03.4 Incomplete, without complication	0.000	0.873	0.127
O08.1 Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy	0.000	0.875	0.125
O62 Abnormalities of forces of labour	0.000	0.876	0.124
O82.1 Delivery by emergency Caesarean section	0.000	0.877	0.123
O75.8 Other specified complications of labour and delivery	0.000	0.878	0.122
O73.0 Retained placenta, without haemorrhage	0.000	0.882	0.118
O72.0 Third-stage haemorrhage	0.000	0.883	0.117
O69.1 Labour and delivery complicated by cord around neck, with compression	0.000	0.883	0.117
O69.9 Labour and delivery complicated by cord complication, unspecified	0.000	0.884	0.116
O74 Complications of anaesthesia during labour and delivery	0.000	0.885	0.114
O60 Preterm delivery	0.000	0.885	0.114
O02 Other abnormal products of conception	0.000	0.886	0.114
O67.9 Intrapartum haemorrhage, unspecified	0.000	0.888	0.112
O69.0 Labour and delivery complicated by prolapse of cord	0.000	0.891	0.109
O69.2 Labour and delivery complicated by other cord entanglement	0.000	0.891	0.109
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.000	0.892	0.108
O75.2 Pyrexia during labour, not elsewhere classified	0.000	0.893	0.107
O72.3 Postpartum coagulation defects	0.000	0.895	0.105
O82.8 Other single delivery by Caesarean section	0.000	0.896	0.104
O82.2 Delivery by Caesarean hysterectomy	0.000	0.896	0.104
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.000	0.898	0.102
O82.9 Delivery by Caesarean section, unspecified	0.000	0.899	0.101
O62.3 Precipitate labour	0.000	0.899	0.101
O83.9 Assisted single delivery, unspecified	0.000	0.899	0.100
O83.8 Other specified assisted single delivery	0.000	0.899	0.100
O83.4 Destructive operation for delivery	0.000	0.899	0.100
O83.3 Delivery of viable foetus in abdominal pregnancy	0.000	0.899	0.100
O83.2 Other manipulation-assisted delivery	0.000	0.899	0.100
O83.1 Other assisted breech delivery	0.000	0.899	0.100
O83.0 Breech extraction	0.000	0.899	0.100
O84.9 Multiple delivery, unspecified	0.000	0.899	0.100
O84.8 Other multiple delivery	0.000	0.899	0.100
O84.2 Multiple delivery, all by Caesarean section	0.000	0.899	0.100
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.000	0.899	0.100
O84.0 Multiple delivery, all spontaneous	0.000	0.899	0.100
O69.5 Labour and delivery complicated by vascular lesion of cord	0.000	0.900	0.100
O69.4 Labour and delivery complicated by vasa praevia	0.000	0.900	0.100
O69.3 Labour and delivery complicated by short cord	0.000	0.900	0.100
O66 Other obstructed labour	0.000	0.901	0.099
O65 Obstructed labour due to maternal pelvic abnormality	0.000	0.901	0.098
O62.0 Primary inadequate contractions	0.000	0.902	0.098
O75.9 Complication of labour and delivery, unspecified	0.000	0.903	0.097
O75.5 Delayed delivery after artificial rupture of membranes	0.000	0.903	0.097
O75.4 Other complications of obstetric surgery and procedures	0.000	0.903	0.097
O75.3 Other infection during labour	0.000	0.903	0.097
O75.1 Shock during or following labour and delivery	0.000	0.903	0.097
O81 Single delivery by forceps and vacuum extractor	0.001	0.904	0.095
O67.8 Other intrapartum haemorrhage	0.000	0.905	0.095
O67.0 Intrapartum haemorrhage with coagulation defect	0.000	0.905	0.095
O75.0 Maternal distress during labour and delivery	0.000	0.908	0.092
O62.9 Abnormality of forces of labour, unspecified	0.000	0.911	0.089
O62.8 Other abnormalities of forces of labour	0.000	0.911	0.089
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.000	0.913	0.087
O72.1 Other immediate postpartum haemorrhage	0.000	0.914	0.086
O62.2 Other uterine inertia	0.000	0.914	0.086
O04 Medical abortion	0.000	0.916	0.084
O60.3 Preterm delivery without spontaneous labour	0.000	0.918	0.082
O60.2 Preterm spontaneous labour with term delivery	0.000	0.918	0.082
O60.1 Preterm spontaneous labour with preterm delivery	0.000	0.918	0.082
O60.0 Preterm labour without delivery	0.000	0.918	0.082
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.000	0.918	0.082
O74.8 Other complications of anaesthesia during labour and delivery	0.000	0.918	0.082
O74.7 Failed or difficult intubation during labour and delivery	0.000	0.918	0.082
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.000	0.918	0.082
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.000	0.918	0.082
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.000	0.918	0.082
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.000	0.918	0.082
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.000	0.918	0.082
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.000	0.918	0.082
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.000	0.918	0.082
O02.9 Abnormal product of conception, unspecified	0.000	0.918	0.082
O02.8 Other specified abnormal products of conception	0.000	0.918	0.082
O62.1 Secondary uterine inertia	0.000	0.918	0.082
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.000	0.920	0.080
O82.0 Delivery by elective Caesarean section	0.000	0.920	0.079
O61 Failed induction of labour	0.000	0.926	0.073
O66.9 Obstructed labour, unspecified	0.000	0.929	0.071
O66.8 Other specified obstructed labour	0.000	0.929	0.071
O66.3 Obstructed labour due to other abnormalities of foetus	0.000	0.929	0.071
O66.2 Obstructed labour due to unusually large foetus	0.000	0.929	0.071
O66.1 Obstructed labour due to locked twins	0.000	0.929	0.071
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.000	0.929	0.071
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.000	0.929	0.071
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.000	0.929	0.071
O65.2 Obstructed labour due to pelvic inlet contraction	0.000	0.929	0.071
O65.1 Obstructed labour due to generally contracted pelvis	0.000	0.929	0.071
O65.0 Obstructed labour due to deformed pelvis	0.000	0.929	0.071
O69.8 Labour and delivery complicated by other cord complications	0.000	0.930	0.070
O81.5 Delivery by combination of forceps and vacuum extractor	0.001	0.931	0.068
O81.3 Other and unspecified forceps delivery	0.001	0.931	0.068
O81.2 Mid-cavity forceps with rotation	0.001	0.931	0.068
O81.1 Mid-cavity forceps delivery	0.001	0.931	0.068
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.000	0.931	0.068
O70 Perineal laceration during delivery	0.000	0.931	0.069
O81.0 Low forceps delivery	0.001	0.934	0.066
O71 Other obstetric trauma	0.000	0.935	0.064
O02.0 Blighted ovum and nonhydatidiform mole	0.000	0.935	0.064
O75.7 Vaginal delivery following previous Caesarean section	0.000	0.938	0.061
O66.4 Failed trial of labour, unspecified	0.000	0.939	0.061
O04.8 Complete or unspecified, with other and unspecified complications	0.000	0.939	0.060
O04.7 Complete or unspecified, complicated by embolism	0.000	0.939	0.060
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.000	0.939	0.060
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.000	0.939	0.060
O04.3 Incomplete, with other and unspecified complications	0.000	0.939	0.060
O04.2 Incomplete, complicated by embolism	0.000	0.939	0.060
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.000	0.939	0.060
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.940	0.060
O70.9 Perineal laceration during delivery, unspecified	0.000	0.941	0.059
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.000	0.942	0.058
O61.8 Other failed induction of labour	0.000	0.947	0.053
O61.1 Failed instrumental induction of labour	0.000	0.947	0.053
O66.0 Obstructed labour due to shoulder dystocia	0.000	0.949	0.051
O64 Obstructed labour due to malposition and malpresentation of foetus	0.000	0.949	0.051
O80 Single spontaneous delivery	0.000	0.950	0.050
O70.3 Fourth degree perineal laceration during delivery	0.000	0.952	0.047
O02.1 Missed abortion	0.000	0.953	0.047
O71.9 Obstetric trauma, unspecified	0.000	0.953	0.046
O71.6 Obstetric damage to pelvic joints and ligaments	0.000	0.953	0.046
O71.3 Obstetric laceration of cervix	0.000	0.953	0.046
O71.2 Postpartum inversion of uterus	0.000	0.953	0.046
O71.1 Rupture of uterus during labour	0.000	0.953	0.046
O71.0 Rupture of uterus before onset of labour	0.000	0.953	0.046
O71.5 Other obstetric injury to pelvic organs	0.000	0.954	0.046
O61.9 Failed induction of labour, unspecified	0.001	0.954	0.045
O70.2 Third degree perineal laceration during delivery	0.000	0.958	0.042
O71.4 Obstetric high vaginal laceration alone	0.000	0.962	0.038
O70.0 First degree perineal laceration during delivery	0.000	0.962	0.038
O71.8 Other specified obstetric trauma	0.000	0.963	0.036
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.000	0.963	0.036
O64.8 Obstructed labour due to other malposition and malpresentation	0.000	0.963	0.036
O64.5 Obstructed labour due to compound presentation	0.000	0.963	0.036
O64.4 Obstructed labour due to shoulder presentation	0.000	0.963	0.036
O64.3 Obstructed labour due to brow presentation	0.000	0.963	0.036
O80.1 Spontaneous breech delivery	0.000	0.964	0.036
O71.7 Obstetric haematoma of pelvis	0.001	0.964	0.035
Z50.8 Care involving use of rehabilitation procedures	0.034	0.966	0.000
O63 Long labour	0.000	0.966	0.034
O80.8 Other single spontaneous delivery	0.000	0.967	0.033
O64.2 Obstructed labour due to face presentation	0.000	0.968	0.032
O04.4 Incomplete, without complication	0.001	0.969	0.031
O81.4 Vacuum extractor delivery	0.001	0.969	0.029
O04.9 Complete or unspecified, without complication	0.000	0.971	0.029
O61.0 Failed medical induction of labour	0.001	0.972	0.028
Z36.0 Antenatal screening for chromosomal anomalies	0.000	0.974	0.026
O80.9 Single spontaneous delivery, unspecified	0.000	0.975	0.025
O63.2 Delayed delivery of second twin, triplet, etc.	0.000	0.975	0.025
Z36 Antenatal screening	0.000	0.975	0.025
O64.1 Obstructed labour due to breech presentation	0.001	0.976	0.024
Z36.8 Other antenatal screening	0.000	0.976	0.024
Z36.9 Antenatal screening, unspecified	0.000	0.978	0.022
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.000	0.980	0.020
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.000	0.980	0.020
Z36.1 Antenatal screening for raised alphafetoprotein level	0.000	0.980	0.020
O70.1 Second degree perineal laceration during delivery	0.000	0.981	0.019
O63.0 Prolonged first stage (of labour)	0.000	0.981	0.019
Z36.5 Antenatal screening for isoimmunisation	0.000	0.982	0.018
Z36.2 Other antenatal screening based on amniocentesis	0.000	0.982	0.018
O63.9 Long labour, unspecified	0.000	0.984	0.016
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.000	0.984	0.016
H66.3 Other chronic suppurative otitis media	0.000	0.987	0.013
H66.9 Otitis media, unspecified	0.000	0.987	0.013
H66 Suppurative and unspecified otitis media	0.000	0.988	0.012
H81.0 Meniere's disease	0.000	0.988	0.012
O68 Labour and delivery complicated by foetal stress [distress]	0.000	0.989	0.011
H65-H75 Diseases of middle ear and mastoid	0.000	0.990	0.010
H25.0 Senile incipient cataract	0.000	0.990	0.010
H72 Perforation of tympanic membrane	0.000	0.990	0.010
H66.4 Suppurative otitis media, unspecified	0.000	0.990	0.009
H81 Disorders of vestibular function	0.000	0.991	0.009
H66.0 Acute suppurative otitis media	0.000	0.991	0.009
H80-H83 Diseases of inner ear	0.000	0.991	0.009
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.991	0.009
H72.0 Central perforation of tympanic membrane	0.000	0.991	0.009
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.991	0.009
H65 Nonsuppurative otitis media	0.000	0.991	0.009
H35.0 Background retinopathy and retinal vascular changes	0.000	0.992	0.008
H71 Cholesteatoma of middle ear	0.000	0.992	0.008
Chapter VIII Diseases of the ear and mastoid process	0.000	0.992	0.008
H83.0 Labyrinthitis	0.000	0.992	0.008
H83 Other diseases of inner ear	0.000	0.992	0.008
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.992	0.008
H67 Otitis media in diseases classified elsewhere	0.000	0.992	0.008
H81.9 Disorder of vestibular function, unspecified	0.000	0.992	0.007
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.000	0.993	0.007
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.993	0.007
H65.0 Acute serous otitis media	0.000	0.993	0.007
H81.3 Other peripheral vertigo	0.000	0.993	0.007
H60-H62 Diseases of external ear	0.000	0.993	0.007
H72.2 Other marginal perforations of tympanic membrane	0.000	0.993	0.007
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.993	0.007
D22.5 Melanocytic naevi of trunk	0.000	0.993	0.007
H73 Other disorders of tympanic membrane	0.000	0.993	0.007
H61 Other disorders of external ear	0.000	0.993	0.007
H72.1 Attic perforation of tympanic membrane	0.000	0.993	0.007
H81.4 Vertigo of central origin	0.000	0.993	0.007
H68 Eustachian salpingitis and obstruction	0.000	0.993	0.007
H61.9 Disorder of external ear, unspecified	0.000	0.993	0.007
H82 Vertiginous syndromes in diseases classified elsewhere	0.000	0.993	0.007
H74 Other disorders of middle ear and mastoid	0.000	0.993	0.007
L08.8 Other specified local infections of skin and subcutaneous tissue	0.007	0.993	0.000
H72.8 Other perforations of tympanic membrane	0.000	0.993	0.006
H80 Otosclerosis	0.000	0.993	0.006
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.000	0.993	0.006
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.000	0.994	0.006
H61.1 Non-infective disorders of pinna	0.000	0.994	0.006
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.000	0.994	0.006
H81.8 Other disorders of vestibular function	0.000	0.994	0.006
H70 Mastoiditis and related conditions	0.000	0.994	0.006
H65.3 Chronic mucoid otitis media	0.000	0.994	0.006
H83.3 Noise effects on inner ear	0.000	0.994	0.006
H83.2 Labyrinthine dysfunction	0.000	0.994	0.006
H83.1 Labyrinthine fistula	0.000	0.994	0.006
H61.3 Acquired stenosis of external ear canal	0.000	0.994	0.006
H61.8 Other specified disorders of external ear	0.000	0.994	0.006
H74.0 Tympanosclerosis	0.000	0.994	0.006
H81.1 Benign paroxysmal vertigo	0.000	0.994	0.006
H69 Other disorders of Eustachian tube	0.000	0.994	0.006
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.994	0.006
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.994	0.006
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.994	0.006
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.994	0.006
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.994	0.006
R82.7 Abnormal findings on microbiological examination of urine	0.006	0.994	0.000
H65.2 Chronic serous otitis media	0.000	0.994	0.005
H62 Disorders of external ear in diseases classified elsewhere	0.000	0.994	0.005
H65.4 Other chronic nonsuppurative otitis media	0.000	0.994	0.005
H73.1 Chronic myringitis	0.000	0.995	0.005
H73.0 Acute myringitis	0.000	0.995	0.005
H65.1 Other acute nonsuppurative otitis media	0.000	0.995	0.005
H73.8 Other specified disorders of tympanic membrane	0.000	0.995	0.005
H83.8 Other specified diseases of inner ear	0.000	0.995	0.005
H81.2 Vestibular neuronitis	0.000	0.995	0.005
H68.0 Eustachian salpingitis	0.000	0.995	0.005
H83.9 Disease of inner ear, unspecified	0.000	0.995	0.005
H60 Otitis externa	0.000	0.995	0.005
H74.4 Polyp of middle ear	0.000	0.995	0.005
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.995	0.005
H80.8 Other otosclerosis	0.000	0.995	0.005
H80.2 Cochlear otosclerosis	0.000	0.995	0.005
H80.1 Otosclerosis involving oval window, obliterative	0.000	0.995	0.005
H80.0 Otosclerosis involving oval window, nonobliterative	0.000	0.995	0.005
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.995	0.005
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.995	0.005
H74.1 Adhesive middle ear disease	0.000	0.995	0.005
H60.3 Other infective otitis externa	0.000	0.995	0.005
H68.1 Obstruction of Eustachian tube	0.000	0.995	0.004
H80.9 Otosclerosis, unspecified	0.000	0.995	0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations