TreeWAS – Variant ID: rs28447319

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T83.0 Mechanical complication of urinary (indwelling) catheter	0.024	0.976	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.023	0.977	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.022	0.978	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.020	0.979	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.020	0.980	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.019	0.981	0.000
K62.8 Other specified diseases of anus and rectum	0.017	0.983	0.000
T83.2 Mechanical complication of graft of urinary organ	0.016	0.984	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.016	0.984	0.000
K62.3 Rectal prolapse	0.015	0.985	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.015	0.985	0.000
K62 Other diseases of anus and rectum	0.012	0.988	0.000
K62.0 Anal polyp	0.012	0.988	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.990	0.010
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.009	0.990	0.000
N85.2 Hypertrophy of uterus	0.000	0.991	0.009
K62.4 Stenosis of anus and rectum	0.009	0.991	0.000
K62.2 Anal prolapse	0.009	0.991	0.000
K62.7 Radiation proctitis	0.008	0.992	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.993	0.007
K62.9 Disease of anus and rectum, unspecified	0.007	0.993	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.993	0.007
K62.6 Ulcer of anus and rectum	0.006	0.993	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.994	0.006
E05.5 Thyroid crisis or storm	0.000	0.994	0.005
E05.4 Thyrotoxicosis factitia	0.000	0.994	0.005
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.994	0.005
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.994	0.005
E05.8 Other thyrotoxicosis	0.000	0.994	0.005
D26.1 Corpus uteri	0.004	0.996	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.000	0.996	0.004
N85 Other noninflammatory disorders of uterus, except cervix	0.000	0.996	0.004
R87.6 Abnormal cytological findings	0.004	0.996	0.000
N43.3 Hydrocele, unspecified	0.004	0.996	0.000
N30.9 Cystitis, unspecified	0.004	0.996	0.000
K70.3 Alcoholic cirrhosis of liver	0.004	0.996	0.000
N85.4 Malposition of uterus	0.000	0.996	0.004
N85.0 Endometrial glandular hyperplasia	0.000	0.996	0.004
N85.6 Intra-uterine synechiae	0.000	0.997	0.003
C90.0 Multiple myeloma	0.003	0.997	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.003	0.997	0.000
N85.7 Haematometra	0.000	0.997	0.003
N85.5 Inversion of uterus	0.000	0.997	0.003
N85.3 Subinvolution of uterus	0.000	0.997	0.003
S46.0 Injury of tendon of the rotator cuff of shoulder	0.003	0.997	0.000
K70 Alcoholic liver disease	0.003	0.997	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.000	0.997	0.003
D89.2 Hypergammaglobulinaemia, unspecified	0.003	0.997	0.000
R00.2 Palpitations	0.003	0.997	0.000
K70.4 Alcoholic hepatic failure	0.003	0.997	0.000
C77.1 Intrathoracic lymph nodes	0.003	0.997	0.000
L53.9 Erythematous condition, unspecified	0.003	0.997	0.000
B02.9 Zoster without complication	0.000	0.997	0.003
K70.9 Alcoholic liver disease, unspecified	0.003	0.997	0.000
K70.0 Alcoholic fatty liver	0.003	0.997	0.000
N85.9 Noninflammatory disorder of uterus, unspecified	0.000	0.997	0.003
N85.1 Endometrial adenomatous hyperplasia	0.000	0.997	0.002
S46 Injury of muscle and tendon at shoulder and upper arm level	0.003	0.997	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.002	0.998	0.000
K70.1 Alcoholic hepatitis	0.002	0.998	0.000
H72 Perforation of tympanic membrane	0.002	0.998	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.002	0.998	0.000
H72.0 Central perforation of tympanic membrane	0.002	0.998	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.002	0.998	0.000
N43.1 Infected hydrocele	0.002	0.998	0.000
N90.6 Hypertrophy of vulva	0.002	0.998	0.000
S46.3 Injury of muscle and tendon of triceps	0.002	0.998	0.000
N43 Hydrocele and spermatocele	0.002	0.998	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.998	0.002
K62.5 Haemorrhage of anus and rectum	0.002	0.998	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.002	0.998	0.000
D86.0 Sarcoidosis of lung	0.002	0.998	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.002	0.998	0.000
S72.30 Fracture of shaft of femur (closed)	0.002	0.998	0.000
H72.2 Other marginal perforations of tympanic membrane	0.002	0.998	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.002	0.998	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.002	0.998	0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.002	0.998	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.002	0.998	0.000
H72.1 Attic perforation of tympanic membrane	0.002	0.998	0.000
K63.9 Disease of intestine, unspecified	0.000	0.998	0.002
Y51 Drugs primarily affecting the autonomic nervous system	0.000	0.998	0.002
N43.4 Spermatocele	0.002	0.998	0.000
N43.2 Other hydrocele	0.002	0.998	0.000
N43.0 Encysted hydrocele	0.002	0.998	0.000
R87 Abnormal findings in specimens from female genital organs	0.002	0.998	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.002	0.998	0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.000	0.998	0.002
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
H66.9 Otitis media, unspecified	0.002	0.998	0.000
O73.0 Retained placenta, without haemorrhage	0.002	0.998	0.000
K62.1 Rectal polyp	0.002	0.998	0.000
D86.9 Sarcoidosis, unspecified	0.002	0.998	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.002	0.998	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
D89.3 Immune reconstitution syndrome	0.002	0.998	0.000
D89.1 Cryoglobulinaemia	0.002	0.998	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.002	0.998	0.000
S99.9 Unspecified injury of ankle and foot	0.002	0.998	0.000
D86 Sarcoidosis	0.002	0.998	0.000
H72.8 Other perforations of tympanic membrane	0.002	0.998	0.000
T78.4 Allergy, unspecified	0.000	0.998	0.002
L53 Other erythematous conditions	0.002	0.998	0.000
N86 Erosion and ectropion of cervix uteri	0.002	0.998	0.000
S41.0 Open wound of shoulder	0.002	0.998	0.000
B02 Zoster [herpes zoster]	0.000	0.998	0.002
S92.20 Fracture of other tarsal bone(s) (closed)	0.002	0.998	0.000
S92.70 Multiple fractures of foot (closed)	0.002	0.998	0.000
K91.3 Postoperative intestinal obstruction	0.000	0.998	0.002
M06.9 Rheumatoid arthritis, unspecified	0.000	0.998	0.002
B02.3 Zoster ocular disease	0.000	0.998	0.002
K58.0 Irritable bowel syndrome with diarrhoea	0.000	0.998	0.002
S72.3 Fracture of shaft of femur	0.002	0.998	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.998	0.002
S92.0 Fracture of calcaneus	0.002	0.998	0.000
Z48.8 Other specified surgical follow-up care	0.000	0.998	0.002
K25.3 Acute without haemorrhage or perforation	0.000	0.998	0.002
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.998	0.002
D17.9 Benign lipomatous neoplasm, unspecified	0.002	0.998	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.000	0.998	0.001
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.998	0.001
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.000	0.998	0.001
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.001
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.001
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.000	0.998	0.001
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.998	0.001
Y51.1 Other parasympathomimetics [cholinergics]	0.000	0.998	0.001
Y51.0 Anticholinesterase agents	0.000	0.998	0.001
D26 Other benign neoplasms of uterus	0.002	0.998	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.002	0.998	0.000
S82.10 Fracture of upper end of tibia (closed)	0.000	0.998	0.002
R87.9 Unspecified abnormal finding	0.001	0.998	0.000
R87.8 Other abnormal findings	0.001	0.998	0.000
R87.5 Abnormal microbiological findings	0.001	0.998	0.000
R87.4 Abnormal immunological findings	0.001	0.998	0.000
R87.3 Abnormal level of substances chiefly nonmedicinal as to source	0.001	0.998	0.000
R87.2 Abnormal level of other drugs, medicaments and biological substances	0.001	0.998	0.000
R87.1 Abnormal level of hormones	0.001	0.998	0.000
R87.0 Abnormal level of enzymes	0.001	0.998	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.998	0.002
F20.0 Paranoid schizophrenia	0.000	0.998	0.002
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
F20.9 Schizophrenia, unspecified	0.000	0.998	0.002
N85.8 Other specified noninflammatory disorders of uterus	0.000	0.998	0.002
S92.7 Multiple fractures of foot	0.002	0.998	0.000
O21.0 Mild hyperemesis gravidarum	0.000	0.998	0.002
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.998	0.002
D86.3 Sarcoidosis of skin	0.001	0.998	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.001	0.998	0.000
R87.7 Abnormal histological findings	0.001	0.998	0.000
S99.8 Other specified injuries of ankle and foot	0.001	0.998	0.000
G25.3 Myoclonus	0.002	0.998	0.000
K65.0 Acute peritonitis	0.002	0.998	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.002	0.998	0.000
C90.3 Solitary plasmacytoma	0.001	0.998	0.000
L53.8 Other specified erythematous conditions	0.001	0.998	0.000
L53.3 Other chronic figurate erythema	0.001	0.998	0.000
L53.2 Erythema marginatum	0.001	0.998	0.000
L53.1 Erythema annulare centrifugum	0.001	0.998	0.000
L53.0 Toxic erythema	0.001	0.998	0.000
L85.9 Epidermal thickening, unspecified	0.000	0.998	0.002
S41 Open wound of shoulder and upper arm	0.002	0.998	0.000
S99 Other and unspecified injuries of ankle and foot	0.002	0.998	0.000
B02.8 Zoster with other complications	0.000	0.998	0.001
B02.7 Disseminated zoster	0.000	0.998	0.001
B02.2 Zoster with other nervous system involvement	0.000	0.998	0.001
B02.1 Zoster meningitis	0.000	0.998	0.001
B02.0 Zoster encephalitis	0.000	0.998	0.001
Z48.0 Attention to surgical dressings and sutures	0.002	0.998	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.998	0.001
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.998	0.001
G70.0 Myasthenia gravis	0.001	0.998	0.000
H61.0 Perichondritis of external ear	0.002	0.998	0.000
H74.0 Tympanosclerosis	0.001	0.998	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.001	0.998	0.000
L60.0 Ingrowing nail	0.002	0.998	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.001	0.998	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.002	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.001	0.998	0.000
S92 Fracture of foot, except ankle	0.002	0.998	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.998	0.001
S72.31 Fracture of shaft of femur (open)	0.001	0.998	0.000
S92.01 Fracture of calcaneus (open)	0.001	0.998	0.000
D26.7 Other parts of uterus	0.001	0.999	0.000
S72.9 Fracture of femur, part unspecified	0.001	0.999	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.001	0.999	0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.001	0.999	0.000
S72.80 Fractures of other parts of femur (closed)	0.001	0.999	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.001	0.999	0.000
A87.9 Viral meningitis, unspecified	0.000	0.999	0.001
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.001	0.999	0.000
O02.1 Missed abortion	0.000	0.999	0.001
M48.07 Spinal stenosis (Lumbosacral region)	0.001	0.999	0.000
S92.71 Multiple fractures of foot (open)	0.001	0.999	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.999	0.001
D26.9 Uterus, unspecified	0.001	0.999	0.000
E16.2 Hypoglycaemia, unspecified	0.000	0.999	0.001
D83 Common variable immunodeficiency	0.001	0.999	0.000
D82 Immunodeficiency associated with other major defects	0.001	0.999	0.000
D81 Combined immunodeficiencies	0.001	0.999	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.001	0.999	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.001	0.999	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.999	0.001
C90.1 Plasma cell leukaemia	0.001	0.999	0.000
D26.0 Cervix uteri	0.001	0.999	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.001	0.999	0.000
H66.4 Suppurative otitis media, unspecified	0.001	0.999	0.000
M20.3 Other deformity of hallux (acquired)	0.001	0.999	0.000
R68.8 Other specified general symptoms and signs	0.001	0.999	0.000
D84 Other immunodeficiencies	0.001	0.999	0.000
H66 Suppurative and unspecified otitis media	0.001	0.999	0.000
F10.2 Dependence syndrome	0.001	0.999	0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.001	0.999	0.000
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.001	0.999	0.000
S41.7 Multiple open wounds of shoulder and upper arm	0.001	0.999	0.000
S72.8 Fractures of other parts of femur	0.001	0.999	0.000
S99.7 Multiple injuries of ankle and foot	0.001	0.999	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.001	0.999	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.001	0.999	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.001	0.999	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.001	0.999	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.001	0.999	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.001	0.999	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.001	0.999	0.000
D86.8 Sarcoidosis of other and combined sites	0.001	0.999	0.000
M24.1 Other articular cartilage disorders	0.001	0.999	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.001	0.999	0.000
S41.1 Open wound of upper arm	0.001	0.999	0.000
S92.9 Fracture of foot, unspecified	0.001	0.999	0.000
S92.5 Fracture of other toe	0.001	0.999	0.000
S72.20 Subtrochanteric fracture (closed)	0.001	0.999	0.000
D86.1 Sarcoidosis of lymph nodes	0.001	0.999	0.000
S72.4 Fracture of lower end of femur	0.001	0.999	0.000
T78.3 Angioneurotic oedema	0.000	0.999	0.001
S40-S49 Injuries to the shoulder and upper arm	0.001	0.999	0.000
S72.41 Fracture of lower end of femur (open)	0.001	0.999	0.000
S72.91 Fracture of femur, part unspecified (open)	0.001	0.999	0.000
L50.8 Other urticaria	0.001	0.999	0.000
S72.2 Subtrochanteric fracture	0.001	0.999	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.001	0.999	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.001	0.999	0.000
S72 Fracture of femur	0.001	0.999	0.000
S49.8 Other specified injuries of shoulder and upper arm	0.001	0.999	0.000
S49.7 Multiple injuries of shoulder and upper arm	0.001	0.999	0.000
S92.1 Fracture of talus	0.001	0.999	0.000
F20 Schizophrenia	0.000	0.999	0.001
S12.20 Fracture of other specified cervical vertebra (closed)	0.001	0.999	0.000
C90.2 Plasmacytoma, extramedullary	0.001	0.999	0.000
D14.0 Middle ear, nasal cavity and accessory sinuses	0.000	0.999	0.001
D80.1 Nonfamilial hypogammaglobulinaemia	0.001	0.999	0.000
D81.9 Combined immunodeficiency, unspecified	0.001	0.999	0.000
D81.8 Other combined immunodeficiencies	0.001	0.999	0.000
D81.7 Major histocompatibility complex class II deficiency	0.001	0.999	0.000
D81.6 Major histocompatibility complex class I deficiency	0.001	0.999	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.001	0.999	0.000
D81.4 Nezelof's syndrome	0.001	0.999	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.001	0.999	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.001	0.999	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.001	0.999	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.001	0.999	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.001	0.999	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.001	0.999	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.001	0.999	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.001	0.999	0.000
D82.2 Immunodeficiency with short-limbed stature	0.001	0.999	0.000
D82.1 Di George's syndrome	0.001	0.999	0.000
D82.0 Wiskott-Aldrich syndrome	0.001	0.999	0.000
D83.9 Common variable immunodeficiency, unspecified	0.001	0.999	0.000
D83.8 Other common variable immunodeficiencies	0.001	0.999	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.001	0.999	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.001	0.999	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.001	0.999	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.001	0.999	0.000
K14.8 Other diseases of tongue	0.001	0.999	0.000
S92.4 Fracture of great toe	0.001	0.999	0.000
S72.40 Fracture of lower end of femur (closed)	0.001	0.999	0.000
D84.8 Other specified immunodeficiencies	0.001	0.999	0.000
D84.1 Defects in the complement system	0.001	0.999	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.001	0.999	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.001	0.999	0.000
H66.0 Acute suppurative otitis media	0.001	0.999	0.000
S11.9 Open wound of neck, part unspecified	0.001	0.999	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.001	0.999	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.001	0.999	0.000
M24.18 Other articular cartilage disorders (Other)	0.001	0.999	0.000
M24.14 Other articular cartilage disorders (Hand)	0.001	0.999	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.001	0.999	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.001	0.999	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.001	0.999	0.000
S72.81 Fractures of other parts of femur (open)	0.001	0.999	0.000
S92.51 Fracture of other toe (open)	0.001	0.999	0.000
S92.91 Fracture of foot, unspecified (open)	0.001	0.999	0.000
S92.90 Fracture of foot, unspecified (closed)	0.001	0.999	0.000
D84.9 Immunodeficiency, unspecified	0.001	0.999	0.000
H74 Other disorders of middle ear and mastoid	0.001	0.999	0.000
S92.50 Fracture of other toe (closed)	0.001	0.999	0.000
D05.0 Lobular carcinoma in situ	0.000	0.999	0.001
H74.3 Other acquired abnormalities of ear ossicles	0.001	0.999	0.000
S48 Traumatic amputation of shoulder and upper arm	0.001	0.999	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.001	0.999	0.000
S44 Injury of nerves at shoulder and upper arm level	0.001	0.999	0.000
S40 Superficial injury of shoulder and upper arm	0.001	0.999	0.000
S47 Crushing injury of shoulder and upper arm	0.001	0.999	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.001	0.999	0.000
S72.21 Subtrochanteric fracture (open)	0.001	0.999	0.000
S72.7 Multiple fractures of femur	0.001	0.999	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.999	0.001
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.999	0.001
S92.11 Fracture of talus (open)	0.001	0.999	0.000
F20.8 Other schizophrenia	0.000	0.999	0.001
F20.6 Simple schizophrenia	0.000	0.999	0.001
F20.5 Residual schizophrenia	0.000	0.999	0.001
F20.4 Postschizophrenic depression	0.000	0.999	0.001
F20.3 Undifferentiated schizophrenia	0.000	0.999	0.001
F20.2 Catatonic schizophrenia	0.000	0.999	0.001
F20.1 Hebephrenic schizophrenia	0.000	0.999	0.001
H61.1 Non-infective disorders of pinna	0.001	0.999	0.000
S43.1 Dislocation of acromioclavicular joint	0.001	0.999	0.000
M84.01 Malunion of fracture (Shoulder region)	0.001	0.999	0.000
H74.1 Adhesive middle ear disease	0.001	0.999	0.000
S92.3 Fracture of metatarsal bone	0.001	0.999	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.001	0.999	0.000
M84.03 Malunion of fracture (Forearm)	0.001	0.999	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.001	0.999	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.001	0.999	0.000
N48.0 Leukoplakia of penis	0.001	0.999	0.000
T40.2 Other opioids	0.001	0.999	0.000
S92.41 Fracture of great toe (open)	0.001	0.999	0.000
S40.8 Other superficial injuries of shoulder and upper arm	0.001	0.999	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.001	0.999	0.000
S44.9 Injury of unspecified nerve at shoulder and upper arm level	0.001	0.999	0.000
S44.8 Injury of other nerves at shoulder and upper arm level	0.001	0.999	0.000
S44.7 Injury of multiple nerves at shoulder and upper arm level	0.001	0.999	0.000
S44.5 Injury of cutaneous sensory nerve at shoulder and upper arm level	0.001	0.999	0.000
S44.4 Injury of musculocutaneous nerve	0.001	0.999	0.000
S44.3 Injury of axillary nerve	0.001	0.999	0.000
S44.2 Injury of radial nerve at upper arm level	0.001	0.999	0.000
S44.1 Injury of median nerve at upper arm level	0.001	0.999	0.000
S44.0 Injury of ulnar nerve at upper arm level	0.001	0.999	0.000
S45.9 Injury of unspecified blood vessel at shoulder and upper arm level	0.001	0.999	0.000
S45.8 Injury of other blood vessels at shoulder and upper arm level	0.001	0.999	0.000
S45.7 Injury of multiple blood vessels at shoulder and upper arm level	0.001	0.999	0.000
S45.3 Injury of superficial vein at shoulder and upper arm level	0.001	0.999	0.000
S45.2 Injury of axillary or brachial vein	0.001	0.999	0.000
S45.1 Injury of brachial artery	0.001	0.999	0.000
S45.0 Injury of axillary artery	0.001	0.999	0.000
S48.9 Traumatic amputation of shoulder and upper arm, level unspecified	0.001	0.999	0.000
S48.1 Traumatic amputation at level between shoulder and elbow	0.001	0.999	0.000
S48.0 Traumatic amputation at shoulder joint	0.001	0.999	0.000
D05 Carcinoma in situ of breast	0.000	0.999	0.001
N19 Unspecified renal failure	0.001	0.999	0.000
H65-H75 Diseases of middle ear and mastoid	0.001	0.999	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.999	0.001
M84.05 Malunion of fracture (Pelvic region and thigh)	0.001	0.999	0.000
S72.71 Multiple fractures of femur (open)	0.001	0.999	0.000
S72.70 Multiple fractures of femur (closed)	0.001	0.999	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.001	0.999	0.000
S92.10 Fracture of talus (closed)	0.001	0.999	0.000
S92.31 Fracture of metatarsal bone (open)	0.001	0.999	0.000
S92.40 Fracture of great toe (closed)	0.001	0.999	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.001	0.999	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.001	0.999	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.001	0.999	0.000
S43.4 Sprain and strain of shoulder joint	0.001	0.999	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.001	0.999	0.000
S43.2 Dislocation of sternoclavicular joint	0.001	0.999	0.000
C78.0 Secondary malignant neoplasm of lung	0.001	0.999	0.000
F06.7 Mild cognitive disorder	0.001	0.999	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.001	0.999	0.000
I69.3 Sequelae of cerebral infarction	0.000	0.999	0.001
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.001	0.999	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.001	0.999	0.000
D05.7 Other carcinoma in situ of breast	0.000	0.999	0.001
M84.0 Malunion of fracture	0.001	0.999	0.000
T42.1 Iminostilbenes	0.001	0.999	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.001	0.999	0.000
H68 Eustachian salpingitis and obstruction	0.001	0.999	0.000
H67 Otitis media in diseases classified elsewhere	0.001	0.999	0.000
S32.30 Fracture of ilium (closed)	0.000	0.999	0.001
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.999	0.001
T78 Adverse effects, not elsewhere classified	0.000	0.999	0.001
M06.34 Rheumatoid nodule (Hand)	0.000	0.999	0.001
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.001	0.999	0.000
M84.09 Malunion of fracture (Site unspecified)	0.001	0.999	0.000
M84.08 Malunion of fracture (Other)	0.001	0.999	0.000
M84.06 Malunion of fracture (Lower leg)	0.001	0.999	0.000
M84.02 Malunion of fracture (Upper arm)	0.001	0.999	0.000
M84.00 Malunion of fracture (Multiple sites)	0.001	0.999	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.001	0.999	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.001	0.999	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.001	0.999	0.000
H68.1 Obstruction of Eustachian tube	0.001	0.999	0.000
H68.0 Eustachian salpingitis	0.001	0.999	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.001	0.999	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.999	0.001
H61 Other disorders of external ear	0.001	0.999	0.000
L50 Urticaria	0.001	0.999	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.001	0.999	0.000
Q89.2 Congenital malformations of other endocrine glands	0.001	0.999	0.000
S72.1 Pertrochanteric fracture	0.001	0.999	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.001	0.999	0.000
T78.9 Adverse effect, unspecified	0.000	0.999	0.001
T78.8 Other adverse effects, not elsewhere classified	0.000	0.999	0.001
W10.8 Other specified place	0.000	0.999	0.001
S90-S99 Injuries to the ankle and foot	0.001	0.999	0.000
M84.04 Malunion of fracture (Hand)	0.001	0.999	0.000
S32.50 Fracture of pubis (closed)	0.000	0.999	0.001
S72.11 Pertrochanteric fracture (open)	0.001	0.999	0.000
L50.6 Contact urticaria	0.001	0.999	0.000
L50.5 Cholinergic urticaria	0.001	0.999	0.000
L50.4 Vibratory urticaria	0.001	0.999	0.000
L50.3 Dermatographic urticaria	0.001	0.999	0.000
L50.2 Urticaria due to cold and heat	0.001	0.999	0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.000	0.999	0.001
Q27.3 Peripheral arteriovenous malformation	0.001	0.999	0.000
S12.2 Fracture of other specified cervical vertebra	0.001	0.999	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.001	0.999	0.000
Z73.3 Stress, not elsewhere classified	0.000	0.999	0.001
G25 Other extrapyramidal and movement disorders	0.001	0.999	0.000
S98 Traumatic amputation of ankle and foot	0.001	0.999	0.000
S97 Crushing injury of ankle and foot	0.001	0.999	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.001	0.999	0.000
S95 Injury of blood vessels at ankle and foot level	0.001	0.999	0.000
S94 Injury of nerves at ankle and foot level	0.001	0.999	0.000
M62.11 Other rupture of muscle (nontraumatic) (Shoulder region)	0.001	0.999	0.000
S12.21 Fracture of other specified cervical vertebra (open)	0.001	0.999	0.000
B44.1 Other pulmonary aspergillosis	0.000	0.999	0.001
G25.9 Extrapyramidal and movement disorder, unspecified	0.001	0.999	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.001	0.999	0.000
G25.5 Other chorea	0.001	0.999	0.000
G25.4 Drug-induced chorea	0.001	0.999	0.000
G25.2 Other specified forms of tremor	0.001	0.999	0.000
G25.1 Drug-induced tremor	0.001	0.999	0.000
H69.8 Other specified disorders of Eustachian tube	0.001	0.999	0.000
H69.0 Patulous Eustachian tube	0.001	0.999	0.000
J01.0 Acute maxillary sinusitis	0.001	0.999	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.001	0.999	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.001	0.999	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.001	0.999	0.000
S90.3 Contusion of other and unspecified parts of foot	0.001	0.999	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.001	0.999	0.000
S94.8 Injury of other nerves at ankle and foot level	0.001	0.999	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.001	0.999	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.001	0.999	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.001	0.999	0.000
S94.1 Injury of medial plantar nerve	0.001	0.999	0.000
S94.0 Injury of lateral plantar nerve	0.001	0.999	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.001	0.999	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.001	0.999	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.001	0.999	0.000
S95.2 Injury of dorsal vein of foot	0.001	0.999	0.000
S95.1 Injury of plantar artery of foot	0.001	0.999	0.000
S95.0 Injury of dorsal artery of foot	0.001	0.999	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.001	0.999	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.001	0.999	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.001	0.999	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.001	0.999	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.001	0.999	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.001	0.999	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.001	0.999	0.000
S97.1 Crushing injury of toe(s)	0.001	0.999	0.000
S97.0 Crushing injury of ankle	0.001	0.999	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.001	0.999	0.000
S98.3 Traumatic amputation of other parts of foot	0.001	0.999	0.000
S98.2 Traumatic amputation of two or more toes	0.001	0.999	0.000
S98.1 Traumatic amputation of one toe	0.001	0.999	0.000
S98.0 Traumatic amputation of foot at ankle level	0.001	0.999	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.001	0.999	0.000
G70 Myasthenia gravis and other myoneural disorders	0.001	0.999	0.000
H70 Mastoiditis and related conditions	0.001	0.999	0.000
H69 Other disorders of Eustachian tube	0.001	0.999	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.001	0.999	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.001	0.999	0.000
S93.40 Sprain of unspecified ligament of ankle	0.001	0.999	0.000
C43.9 Malignant melanoma of skin, unspecified	0.001	0.999	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.999	0.001
C80.0 Malignant neoplasm, primary site unknown, so stated	0.001	0.999	0.000
G70.9 Myoneural disorder, unspecified	0.001	0.999	0.000
G70.8 Other specified myoneural disorders	0.001	0.999	0.000
G70.2 Congenital and developmental myasthenia	0.001	0.999	0.000
G70.1 Toxic myoneural disorders	0.001	0.999	0.000
H70.8 Other mastoiditis and related conditions	0.001	0.999	0.000
H70.2 Petrositis	0.001	0.999	0.000
H70.1 Chronic mastoiditis	0.001	0.999	0.000
H70.0 Acute mastoiditis	0.001	0.999	0.000
L50.1 Idiopathic urticaria	0.001	0.999	0.000
S93.4 Sprain and strain of ankle	0.001	0.999	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.001	0.999	0.000
S93.5 Sprain and strain of toe(s)	0.001	0.999	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.001	0.999	0.000
S93.1 Dislocation of toe(s)	0.001	0.999	0.000
M54.12 Radiculopathy (Cervical region)	0.001	0.999	0.000
J99.8 Respiratory disorders in other diseases classified elsewhere	0.000	0.999	0.001
K91.4 Colostomy and enterostomy malfunction	0.000	0.999	0.001
L51.9 Erythema multiforme, unspecified	0.001	0.999	0.000
L51.8 Other erythema multiforme	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations