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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2853933
log Bayes Factor = 156.443
Chromosome 6   position 31,254,088  (GRCh37) Explore rs2853933 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
G35 Multiple sclerosis
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
D50-D53 Nutritional anaemias
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
L40-L45 Papulosquamous disorders
0.999 0.001 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.999 0.001 0.000
D80-D89 Certain disorders involving the immune mechanism
0.999 0.001 0.000
D86 Sarcoidosis
0.998 0.002 0.000
K90 Intestinal malabsorption
0.997 0.003 0.000
D51 Vitamin B12 deficiency anaemia
0.997 0.003 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.996 0.004 0.000
L40.0 Psoriasis vulgaris
0.996 0.004 0.000
K70-K77 Diseases of liver
0.993 0.007 0.000
Chapter XI Diseases of the digestive system
0.993 0.007 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.993 0.007 0.000
K90-K93 Other diseases of the digestive system
0.992 0.008 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.991 0.009 0.000
E50-E64 Other nutritional deficiencies
0.990 0.010 0.000
D69 Purpura and other haemorrhagic conditions
0.990 0.010 0.000
K75 Other inflammatory liver diseases
0.989 0.011 0.000
D86.9 Sarcoidosis, unspecified
0.988 0.012 0.000
Chapter VI Diseases of the nervous system
0.986 0.014 0.000
E53 Deficiency of other B group vitamins
0.982 0.018 0.000
D60-D64 Aplastic and other anaemias
0.981 0.019 0.000
D50 Iron deficiency anaemia
0.978 0.022 0.000
K75.4 Autoimmune hepatitis
0.978 0.022 0.000
E03 Other hypothyroidism
0.977 0.023 0.000
D64 Other anaemias
0.977 0.023 0.000
L10-L14 Bullous disorders
0.974 0.026 0.000
E53.8 Deficiency of other specified B group vitamins
0.973 0.027 0.000
Chapter I Certain infectious and parasitic diseases
0.973 0.027 0.000
D69.6 Thrombocytopenia, unspecified
0.969 0.031 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.969 0.031 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.968 0.032 0.000
D64.9 Anaemia, unspecified
0.968 0.032 0.000
E27.1 Primary adrenocortical insufficiency
0.964 0.036 0.000
D50.9 Iron deficiency anaemia, unspecified
0.964 0.036 0.000
E27 Other disorders of adrenal gland
0.962 0.038 0.000
E20-E35 Disorders of other endocrine glands
0.962 0.038 0.000
B07 Viral warts
0.956 0.044 0.000
D55-D59 Haemolytic anaemias
0.950 0.050 0.000
K75.8 Other specified inflammatory liver diseases
0.944 0.056 0.000
L13 Other bullous disorders
0.944 0.056 0.000
D86.0 Sarcoidosis of lung
0.942 0.058 0.000
E03.9 Hypothyroidism, unspecified
0.942 0.058 0.000
G37 Other demyelinating diseases of central nervous system
0.931 0.069 0.000
L50-L54 Urticaria and erythema
0.930 0.070 0.000
M45 Ankylosing spondylitis
0.000 0.070 0.930
D69.3 Idiopathic thrombocytopenic purpura
0.927 0.073 0.000
D59 Acquired haemolytic anaemia
0.926 0.074 0.000
L13.0 Dermatitis herpetiformis
0.923 0.077 0.000
E06 Thyroiditis
0.919 0.081 0.000
K73 Chronic hepatitis, not elsewhere classified
0.915 0.085 0.000
B00 Herpesviral [herpes simplex] infections
0.912 0.088 0.000
D72 Other disorders of white blood cells
0.909 0.091 0.000
K72 Hepatic failure, not elsewhere classified
0.908 0.092 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.904 0.096 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.899 0.101 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.104 0.896
D64.8 Other specified anaemias
0.891 0.109 0.000
D86.3 Sarcoidosis of skin
0.889 0.111 0.000
M07.3 Other psoriatic arthropathies
0.888 0.112 0.000
E55 Vitamin D deficiency
0.887 0.113 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.887 0.113 0.000
D70 Agranulocytosis
0.887 0.113 0.000
E03.8 Other specified hypothyroidism
0.880 0.120 0.000
K90.9 Intestinal malabsorption, unspecified
0.878 0.122 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.878 0.122 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.873 0.127 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.873 0.127 0.000
K70 Alcoholic liver disease
0.866 0.134 0.000
D69.4 Other primary thrombocytopenia
0.862 0.138 0.000
E06.3 Autoimmune thyroiditis
0.862 0.138 0.000
E10-E14 Diabetes mellitus
0.861 0.139 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.855 0.145 0.000
D72.8 Other specified disorders of white blood cells
0.853 0.147 0.000
D59.1 Other autoimmune haemolytic anaemias
0.850 0.150 0.000
L50 Urticaria
0.847 0.153 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.846 0.154 0.000
B25-B34 Other viral diseases
0.845 0.155 0.000
E10 Insulin-dependent diabetes mellitus
0.842 0.158 0.000
D69.2 Other nonthrombocytopenic purpura
0.842 0.158 0.000
B01 Varicella [chickenpox]
0.839 0.161 0.000
D53 Other nutritional anaemias
0.838 0.162 0.000
D59.9 Acquired haemolytic anaemia, unspecified
0.836 0.164 0.000
L44 Other papulosquamous disorders
0.834 0.166 0.000
E27.2 Addisonian crisis
0.834 0.166 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.829 0.171 0.000
D69.5 Secondary thrombocytopenia
0.827 0.173 0.000
B35-B49 Mycoses
0.827 0.173 0.000
D61 Other aplastic anaemias
0.825 0.174 0.000
D86.1 Sarcoidosis of lymph nodes
0.824 0.176 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.822 0.178 0.000
B15-B19 Viral hepatitis
0.820 0.180 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.819 0.181 0.000
E10.3 With ophthalmic complications
0.816 0.184 0.000
E55.9 Vitamin D deficiency, unspecified
0.814 0.186 0.000
B37 Candidiasis
0.812 0.188 0.000
L40.1 Generalised pustular psoriasis
0.811 0.189 0.000
G30-G32 Other degenerative diseases of the nervous system
0.807 0.193 0.000
K72.9 Hepatic failure, unspecified
0.807 0.193 0.000
L53 Other erythematous conditions
0.801 0.199 0.000
D50.1 Sideropenic dysphagia
0.799 0.201 0.000
L11 Other acantholytic disorders
0.798 0.202 0.000
E53.9 Vitamin B deficiency, unspecified
0.793 0.207 0.000
B37.8 Candidiasis of other sites
0.792 0.208 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.208 0.792
D69.8 Other specified haemorrhagic conditions
0.789 0.210 0.000
A63.0 Anogenital (venereal) warts
0.789 0.211 0.000
B00.5 Herpesviral ocular disease
0.787 0.213 0.000
D52 Folate deficiency anaemia
0.786 0.214 0.000
E10.2 With renal complications
0.782 0.218 0.000
K70.1 Alcoholic hepatitis
0.777 0.223 0.000
G70-G73 Diseases of myoneural junction and muscle
0.775 0.225 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.770 0.229 0.000
E20 Hypoparathyroidism
0.770 0.230 0.000
L52 Erythema nodosum
0.768 0.232 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.768 0.232 0.000
K72.0 Acute and subacute hepatic failure
0.767 0.233 0.000
E31 Polyglandular dysfunction
0.767 0.233 0.000
B25 Cytomegaloviral disease
0.765 0.235 0.000
E25 Adrenogenital disorders
0.765 0.235 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.765 0.235 0.000
E10.1 With ketoacidosis
0.763 0.237 0.000
E63 Other nutritional deficiencies
0.763 0.237 0.000
L50.9 Urticaria, unspecified
0.761 0.239 0.000
D59.0 Drug-induced autoimmune haemolytic anaemia
0.760 0.240 0.000
L40.3 Pustulosis palmaris et plantaris
0.755 0.245 0.000
D58 Other hereditary haemolytic anaemias
0.752 0.248 0.000
G00 Bacterial meningitis, not elsewhere classified
0.750 0.250 0.000
D80 Immunodeficiency with predominantly antibody defects
0.747 0.253 0.000
B16 Acute hepatitis B
0.744 0.256 0.000
D61.9 Aplastic anaemia, unspecified
0.741 0.259 0.000
K74 Fibrosis and cirrhosis of liver
0.741 0.259 0.000
B00.1 Herpesviral vesicular dermatitis
0.737 0.263 0.000
K50-K52 Noninfective enteritis and colitis
0.736 0.264 0.000
B01.9 Varicella without complications
0.736 0.264 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.735 0.265 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.735 0.265 0.000
D66 Hereditary factor VIII deficiency
0.735 0.265 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.733 0.267 0.000
A20-A28 Certain zoonotic bacterial diseases
0.729 0.271 0.000
D83 Common variable immunodeficiency
0.729 0.271 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.727 0.273 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.723 0.277 0.000
A15-A19 Tuberculosis
0.722 0.277 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.722 0.278 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.722 0.278 0.000
L10 Pemphigus
0.721 0.279 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.719 0.281 0.000
E27.8 Other specified disorders of adrenal gland
0.719 0.281 0.000
L50.1 Idiopathic urticaria
0.718 0.282 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.718 0.282 0.000
D72.1 Eosinophilia
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
L41 Parapsoriasis
0.717 0.283 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.717 0.283 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.717 0.283 0.000
D81 Combined immunodeficiencies
0.716 0.283 0.000
L44.0 Pityriasis rubra pilaris
0.716 0.284 0.000
K90.3 Pancreatic steatorrhoea
0.715 0.285 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.715 0.285 0.000
K90.1 Tropical sprue
0.715 0.285 0.000
D51.2 Transcobalamin II deficiency
0.715 0.285 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.715 0.285 0.000
D89.0 Polyclonal hypergammaglobulinaemia
0.715 0.285 0.000
K77 Liver disorders in diseases classified elsewhere
0.712 0.288 0.000
B65-B83 Helminthiases
0.711 0.288 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.711 0.289 0.000
D67 Hereditary factor IX deficiency
0.711 0.289 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.710 0.290 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.710 0.290 0.000
E50 Vitamin A deficiency
0.710 0.290 0.000
E60 Dietary zinc deficiency
0.710 0.290 0.000
E59 Dietary selenium deficiency
0.710 0.290 0.000
E54 Ascorbic acid deficiency
0.710 0.290 0.000
E52 Niacin deficiency [pellagra]
0.710 0.290 0.000
D69.1 Qualitative platelet defects
0.710 0.290 0.000
K75.2 Nonspecific reactive hepatitis
0.709 0.291 0.000
K75.1 Phlebitis of portal vein
0.709 0.291 0.000
B00.4 Herpesviral encephalitis
0.709 0.291 0.000
B00.8 Other forms of herpesviral infection
0.709 0.291 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.709 0.291 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.708 0.292 0.000
M07.38 Other psoriatic arthropathies (Other)
0.706 0.294 0.000
K70.9 Alcoholic liver disease, unspecified
0.705 0.295 0.000
B37.9 Candidiasis, unspecified
0.704 0.296 0.000
E53.1 Pyridoxine deficiency
0.704 0.296 0.000
E53.0 Riboflavin deficiency
0.704 0.296 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.704 0.296 0.000
K74.0 Hepatic fibrosis
0.703 0.297 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.702 0.298 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.298 0.702
K73.9 Chronic hepatitis, unspecified
0.702 0.298 0.000
E03.5 Myxoedema coma
0.701 0.299 0.000
E03.4 Atrophy of thyroid (acquired)
0.701 0.299 0.000
E03.3 Postinfectious hypothyroidism
0.701 0.299 0.000
D64.4 Congenital dyserythropoietic anaemia
0.701 0.299 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.701 0.299 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.701 0.299 0.000
E51 Thiamine deficiency
0.700 0.299 0.000
L14 Bullous disorders in diseases classified elsewhere
0.698 0.302 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.697 0.302 0.000
A75-A79 Rickettsioses
0.697 0.302 0.000
A70-A74 Other diseases caused by chlamydiae
0.697 0.302 0.000
D73 Diseases of spleen
0.697 0.303 0.000
D64.3 Other sideroblastic anaemias
0.697 0.303 0.000
D64.0 Hereditary sideroblastic anaemia
0.696 0.304 0.000
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis
0.695 0.305 0.000
D53.9 Nutritional anaemia, unspecified
0.695 0.305 0.000
B06 Rubella [German measles]
0.694 0.305 0.000
B05 Measles
0.694 0.305 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.694 0.305 0.000
B04 Monkeypox
0.694 0.305 0.000
B03 Smallpox
0.694 0.305 0.000
D74 Methaemoglobinaemia
0.694 0.306 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.694 0.306 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.694 0.306 0.000
E40-E46 Malnutrition
0.693 0.307 0.000
D82 Immunodeficiency associated with other major defects
0.692 0.308 0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma
0.691 0.309 0.000
E27.5 Adrenomedullary hyperfunction
0.690 0.310 0.000
E27.0 Other adrenocortical overactivity
0.690 0.310 0.000
B37.2 Candidiasis of skin and nail
0.690 0.310 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.689 0.310 0.000
E32 Diseases of thymus
0.689 0.310 0.000
E30 Disorders of puberty, not elsewhere classified
0.689 0.310 0.000
D84 Other immunodeficiencies
0.689 0.311 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.688 0.312 0.000
K52 Other non-infective gastro-enteritis and colitis
0.688 0.312 0.000
E03.1 Congenital hypothyroidism without goitre
0.686 0.314 0.000
A65-A69 Other spirochaetal diseases
0.686 0.314 0.000
L20-L30 Dermatitis and eczema
0.685 0.315 0.000
L12 Pemphigoid
0.682 0.318 0.000
D55 Anaemia due to enzyme disorders
0.681 0.319 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.680 0.320 0.000
B00.9 Herpesviral infection, unspecified
0.679 0.321 0.000
L13.9 Bullous disorder, unspecified
0.677 0.323 0.000
L13.8 Other specified bullous disorders
0.677 0.323 0.000
L13.1 Subcorneal pustular dermatitis
0.677 0.323 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.675 0.325 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.674 0.326 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.674 0.326 0.000
E06.9 Thyroiditis, unspecified
0.671 0.329 0.000
K75.9 Inflammatory liver disease, unspecified
0.670 0.330 0.000
Chapter XXII Codes for special purposes
0.669 0.331 0.000
E58 Dietary calcium deficiency
0.668 0.332 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.668 0.332 0.000
G37.5 Concentric sclerosis [Balo]
0.667 0.332 0.000
G37.4 Subacute necrotising myelitis
0.667 0.332 0.000
G37.2 Central pontine myelinolysis
0.667 0.332 0.000
G37.1 Central demyelination of corpus callosum
0.667 0.332 0.000
G37.0 Diffuse sclerosis
0.667 0.332 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.667 0.332 0.000
D89.1 Cryoglobulinaemia
0.667 0.333 0.000
L54 Erythema in diseases classified elsewhere
0.667 0.333 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.333 0.667
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.333 0.667
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.333 0.667
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.333 0.667
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.333 0.667
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.333 0.667
D59.8 Other acquired haemolytic anaemias
0.664 0.336 0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.664 0.336 0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.664 0.336 0.000
D59.4 Other nonautoimmune haemolytic anaemias
0.664 0.336 0.000
D59.3 Haemolytic-uraemic syndrome
0.664 0.336 0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.664 0.336 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.663 0.337 0.000
E24 Cushing's syndrome
0.660 0.340 0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.659 0.341 0.000
E06.4 Drug-induced thyroiditis
0.659 0.341 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.659 0.341 0.000
E06.1 Subacute thyroiditis
0.659 0.341 0.000
E06.0 Acute thyroiditis
0.659 0.341 0.000
L40.4 Guttate psoriasis
0.658 0.342 0.000
L11.0 Acquired keratosis follicularis
0.657 0.343 0.000
B25.9 Cytomegaloviral disease, unspecified
0.657 0.343 0.000
L42 Pityriasis rosea
0.656 0.344 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.656 0.344 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.656 0.344 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.656 0.344 0.000
L53.0 Toxic erythema
0.655 0.345 0.000
B00.7 Disseminated herpesviral disease
0.654 0.346 0.000
B00.3 Herpesviral meningitis
0.654 0.346 0.000
B00.0 Eczema herpeticum
0.654 0.346 0.000
D72.9 Disorder of white blood cells, unspecified
0.652 0.348 0.000
D72.0 Genetic anomalies of leukocytes
0.652 0.348 0.000
K90.8 Other intestinal malabsorption
0.651 0.348 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.650 0.350 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.650 0.350 0.000
G36 Other acute disseminated demyelination
0.647 0.353 0.000
K75.0 Abscess of liver
0.646 0.354 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.646 0.354 0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.645 0.355 0.000
G06.0 Intracranial abscess and granuloma
0.645 0.355 0.000
D89.3 Immune reconstitution syndrome
0.644 0.356 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.642 0.358 0.000
E06.5 Other chronic thyroiditis
0.639 0.361 0.000
B37.4 Candidiasis of other urogenital sites
0.639 0.361 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.637 0.363 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.637 0.363 0.000
E55.0 Rickets, active
0.636 0.364 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.635 0.365 0.000
L28 Lichen simplex chronicus and prurigo
0.635 0.365 0.000
E20.9 Hypoparathyroidism, unspecified
0.633 0.367 0.000
D52.9 Folate deficiency anaemia, unspecified
0.632 0.368 0.000
B25.0 Cytomegaloviral pneumonitis
0.630 0.370 0.000
G00.1 Pneumococcal meningitis
0.629 0.371 0.000
D69.9 Haemorrhagic condition, unspecified
0.629 0.371 0.000
E31.0 Autoimmune polyglandular failure
0.627 0.373 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.626 0.374 0.000
E10.7 With multiple complications
0.626 0.374 0.000
A59 Trichomoniasis
0.626 0.374 0.000
A56 Other sexually transmitted chlamydial diseases
0.626 0.374 0.000
A54 Gonococcal infection
0.626 0.374 0.000
A53 Other and unspecified syphilis
0.626 0.374 0.000
A52 Late syphilis
0.626 0.374 0.000
A51 Early syphilis
0.626 0.374 0.000
A50 Congenital syphilis
0.626 0.374 0.000
A64 Unspecified sexually transmitted disease
0.626 0.374 0.000
A58 Granuloma inguinale
0.626 0.374 0.000
A57 Chancroid
0.626 0.374 0.000
A55 Chlamydial lymphogranuloma (venereum)
0.626 0.374 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.624 0.376 0.000
B01.2 Varicella pneumonia
0.624 0.376 0.000
D57 Sickle-cell disorders
0.623 0.377 0.000
K72.1 Chronic hepatic failure
0.623 0.377 0.000
B33 Other viral diseases, not elsewhere classified
0.623 0.377 0.000
E56 Other vitamin deficiencies
0.620 0.379 0.000
L53.8 Other specified erythematous conditions
0.620 0.380 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.620 0.380 0.000
L53.9 Erythematous condition, unspecified
0.620 0.380 0.000
D76.3 Other histiocytosis syndromes
0.619 0.380 0.000
E12 Malnutrition-related diabetes mellitus
0.617 0.383 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.617 0.383 0.000
D58.0 Hereditary spherocytosis
0.617 0.383 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.615 0.385 0.000
G71 Primary disorders of muscles
0.615 0.385 0.000
G00.2 Streptococcal meningitis
0.615 0.385 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.614 0.385 0.000
B27 Infectious mononucleosis
0.614 0.385 0.000
B18 Chronic viral hepatitis
0.611 0.389 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.609 0.391 0.000
L50.6 Contact urticaria
0.607 0.393 0.000
L50.5 Cholinergic urticaria
0.607 0.393 0.000
L50.4 Vibratory urticaria
0.607 0.393 0.000
L50.3 Dermatographic urticaria
0.607 0.393 0.000
L50.2 Urticaria due to cold and heat
0.607 0.393 0.000
B30 Viral conjunctivitis
0.606 0.394 0.000
B26 Mumps
0.606 0.394 0.000
B01.8 Varicella with other complications
0.601 0.399 0.000
B01.1 Varicella encephalitis
0.601 0.399 0.000
B01.0 Varicella meningitis
0.601 0.399 0.000
E63.9 Nutritional deficiency, unspecified
0.601 0.399 0.000
D53.8 Other specified nutritional anaemias
0.600 0.399 0.000
D53.2 Scorbutic anaemia
0.600 0.399 0.000
D53.0 Protein deficiency anaemia
0.600 0.399 0.000
B23 Human immunodeficiency virus [HIV] disease resulting in other conditions
0.600 0.399 0.000
E10.8 With unspecified complications
0.600 0.400 0.000
E05.8 Other thyrotoxicosis
0.600 0.400 0.000
L44.9 Papulosquamous disorder, unspecified
0.598 0.402 0.000
L44.8 Other specified papulosquamous disorders
0.598 0.402 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.598 0.402 0.000
L44.3 Lichen ruber moniliformis
0.598 0.402 0.000
L44.2 Lichen striatus
0.598 0.402 0.000
L44.1 Lichen nitidus
0.598 0.402 0.000
B20 Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases
0.597 0.403 0.000
L11.1 Transient acantholytic dermatosis [Grover]
0.597 0.403 0.000
B17 Other acute viral hepatitis
0.597 0.403 0.000
B37.1 Pulmonary candidiasis
0.596 0.404 0.000
E14 Unspecified diabetes mellitus
0.596 0.404 0.000
B22 Human immunodeficiency virus [HIV] disease resulting in other specified diseases
0.594 0.406 0.000
B21 Human immunodeficiency virus [HIV] disease resulting in malignant neoplasms
0.594 0.406 0.000
G70 Myasthenia gravis and other myoneural disorders
0.593 0.407 0.000
B48 Other mycoses, not elsewhere classified
0.593 0.407 0.000
B47 Mycetoma
0.593 0.407 0.000
B46 Zygomycosis
0.593 0.407 0.000
B45 Cryptococcosis
0.593 0.407 0.000
B43 Chromomycosis and phaeomycotic abscess
0.593 0.407 0.000
B42 Sporotrichosis
0.593 0.407 0.000
B41 Paracoccidioidomycosis
0.593 0.407 0.000
B40 Blastomycosis
0.593 0.407 0.000
B39 Histoplasmosis
0.593 0.407 0.000
B38 Coccidioidomycosis
0.593 0.407 0.000
D61.8 Other specified aplastic anaemias
0.592 0.408 0.000
D61.3 Idiopathic aplastic anaemia
0.592 0.408 0.000
D61.2 Aplastic anaemia due to other external agents
0.592 0.408 0.000
D86.8 Sarcoidosis of other and combined sites
0.590 0.410 0.000
K70.3 Alcoholic cirrhosis of liver
0.590 0.410 0.000
B37.7 Candidal septicaemia
0.588 0.412 0.000
K70.0 Alcoholic fatty liver
0.588 0.412 0.000
E23 Hypofunction and other disorders of pituitary gland
0.587 0.413 0.000
L50.0 Allergic urticaria
0.587 0.413 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.584 0.416 0.000
L28.0 Lichen simplex chronicus
0.583 0.417 0.000
B25.8 Other cytomegaloviral diseases
0.582 0.418 0.000
B37.6 Candidal endocarditis
0.582 0.418 0.000
B37.5 Candidal meningitis
0.582 0.418 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.579 0.421 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.578 0.421 0.000
E28 Ovarian dysfunction
0.575 0.424 0.002
L53.3 Other chronic figurate erythema
0.574 0.426 0.000
L53.2 Erythema marginatum
0.574 0.426 0.000
L53.1 Erythema annulare centrifugum
0.574 0.426 0.000
L40.8 Other psoriasis
0.574 0.426 0.000
B36 Other superficial mycoses
0.573 0.426 0.000
L21 Seborrhoeic dermatitis
0.573 0.427 0.000
L11.9 Acantholytic disorder, unspecified
0.572 0.428 0.000
L11.8 Other specified acantholytic disorders
0.572 0.428 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.571 0.429 0.000
G31.0 Circumscribed brain atrophy
0.570 0.430 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.568 0.431 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.566 0.434 0.000
E07 Other disorders of thyroid
0.565 0.435 0.000
D52.8 Other folate deficiency anaemias
0.563 0.437 0.000
D52.1 Drug-induced folate deficiency anaemia
0.563 0.437 0.000
D52.0 Dietary folate deficiency anaemia
0.563 0.437 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.563 0.437 0.000
D61.0 Constitutional aplastic anaemia
0.563 0.437 0.000
A17 Tuberculosis of nervous system
0.561 0.439 0.000
E14.3 With ophthalmic complications
0.561 0.439 0.000
D58.9 Hereditary haemolytic anaemia, unspecified
0.560 0.440 0.000
L50.8 Other urticaria
0.559 0.441 0.000
E10.9 Without complications
0.559 0.441 0.000
D73.1 Hypersplenism
0.555 0.445 0.000
G00.8 Other bacterial meningitis
0.554 0.446 0.000
B80 Enterobiasis
0.554 0.446 0.000
B19 Unspecified viral hepatitis
0.553 0.447 0.000
E20.8 Other hypoparathyroidism
0.552 0.448 0.000
E20.1 Pseudohypoparathyroidism
0.552 0.448 0.000
E20.0 Idiopathic hypoparathyroidism
0.552 0.448 0.000
D61.1 Drug-induced aplastic anaemia
0.552 0.448 0.000
K71 Toxic liver disease
0.551 0.448 0.000
D73.0 Hyposplenism
0.551 0.449 0.000
E31.9 Polyglandular dysfunction, unspecified
0.550 0.450 0.000
E31.8 Other polyglandular dysfunction
0.550 0.450 0.000
E31.1 Polyglandular hyperfunction
0.550 0.450 0.000
K52.3 Indeterminate colitis
0.550 0.450 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.549 0.451 0.000
B25.2 Cytomegaloviral pancreatitis
0.549 0.451 0.000
B25.1 Cytomegaloviral hepatitis
0.549 0.451 0.000
E25.9 Adrenogenital disorder, unspecified
0.549 0.451 0.000
E25.8 Other adrenogenital disorders
0.549 0.451 0.000
D76.2 Haemophagocytic syndrome, infection-associated
0.548 0.451 0.000
D76.1 Haemophagocytic lymphohistiocytosis
0.548 0.451 0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.548 0.451 0.000
E63.8 Other specified nutritional deficiencies
0.547 0.453 0.000
E63.1 Imbalance of constituents of food intake
0.547 0.453 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.547 0.453 0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically
0.546 0.454 0.000
E24.0 Pituitary-dependent Cushing's disease
0.546 0.454 0.000
A60 Anogenital herpesviral [herpes simplex] infections
0.546 0.454 0.000
G06.2 Extradural and subdural abscess, unspecified
0.545 0.455 0.000
E10.6 With other specified complications
0.543 0.457 0.000
D73.5 Infarction of spleen
0.542 0.458 0.000
A27 Leptospirosis
0.541 0.459 0.000
B99-B99 Other infectious diseases
0.540 0.460 0.000
D58.8 Other specified hereditary haemolytic anaemias
0.539 0.460 0.000
D58.1 Hereditary elliptocytosis
0.539 0.460 0.000
G00.3 Staphylococcal meningitis
0.538 0.462 0.000
G00.0 Haemophilus meningitis
0.538 0.462 0.000
A28 Other zoonotic bacterial diseases, not elsewhere classified
0.537 0.462 0.000
B34 Viral infection of unspecified site
0.537 0.463 0.000
D80.8 Other immunodeficiencies with predominantly antibody defects
0.535 0.464 0.000
D80.7 Transient hypogammaglobulinaemia of infancy
0.535 0.464 0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.535 0.464 0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.535 0.464 0.000
D80.0 Hereditary hypogammaglobulinaemia
0.535 0.464 0.000
D83.9 Common variable immunodeficiency, unspecified
0.535 0.465 0.000
L10.0 Pemphigus vulgaris
0.534 0.465 0.000
B16.2 Acute hepatitis B without delta-agent with hepatic coma
0.534 0.466 0.000
B16.1 Acute hepatitis B with delta-agent (coinfection) without hepatic coma
0.534 0.466 0.000
B16.0 Acute hepatitis B with delta-agent (coinfection) with hepatic coma
0.534 0.466 0.000
K74.4 Secondary biliary cirrhosis
0.531 0.469 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.531 0.469 0.000
U89 Agent resistant to other and unspecified antibiotics
0.531 0.469 0.000
B44 Aspergillosis
0.529 0.471 0.000
L10.9 Pemphigus, unspecified
0.524 0.476 0.000
A26 Erysipeloid
0.523 0.477 0.000
A25 Rat-bite fevers
0.523 0.477 0.000
A24 Glanders and melioidosis
0.523 0.477 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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