TreeWAS – Variant ID: rs2858310

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
J45.9 Asthma, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
M05.9 Seropositive rheumatoid arthritis, unspecified	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
G35 Multiple sclerosis	0.000	0.000	1.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
R31 Unspecified haematuria	1.000	0.000	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.000	1.000
D86 Sarcoidosis	0.000	0.000	1.000
M05 Seropositive rheumatoid arthritis	1.000	0.000	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	1.000	0.000	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	1.000	0.000	0.000
D80-D89 Certain disorders involving the immune mechanism	0.000	0.000	1.000
D86.9 Sarcoidosis, unspecified	0.000	0.001	0.999
M05-M14 Inflammatory polyarthropathies	0.999	0.001	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.001	0.999
M06.3 Rheumatoid nodule	0.999	0.001	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.001	0.999
L40.9 Psoriasis, unspecified	0.999	0.001	0.000
J33.9 Nasal polyp, unspecified	0.998	0.002	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.997	0.003	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.996	0.004	0.000
M06.0 Seronegative rheumatoid arthritis	0.995	0.005	0.000
D68 Other coagulation defects	0.000	0.005	0.995
N48 Other disorders of penis	0.992	0.008	0.000
D69 Purpura and other haemorrhagic conditions	0.000	0.015	0.985
N47 Redundant prepuce, phimosis and paraphimosis	0.981	0.019	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.980	0.020	0.000
K90 Intestinal malabsorption	0.000	0.021	0.979
J33 Nasal polyp	0.979	0.021	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.022	0.978
N48.6 Balanitis xerotica obliterans	0.973	0.027	0.000
M06.34 Rheumatoid nodule (Hand)	0.973	0.027	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.970	0.030	0.000
N48.0 Leukoplakia of penis	0.969	0.031	0.000
J33.0 Polyp of nasal cavity	0.968	0.032	0.000
D50-D53 Nutritional anaemias	0.000	0.032	0.968
D86.0 Sarcoidosis of lung	0.000	0.036	0.964
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.962	0.038	0.000
D69.6 Thrombocytopenia, unspecified	0.000	0.040	0.960
N40-N51 Diseases of male genital organs	0.956	0.044	0.000
D68.5 Primary Thrombophilia	0.000	0.045	0.955
E05 Thyrotoxicosis [hyperthyroidism]	0.001	0.055	0.944
K90.9 Intestinal malabsorption, unspecified	0.000	0.057	0.943
E05.9 Thyrotoxicosis, unspecified	0.000	0.060	0.940
E78.0 Pure hypercholesterolaemia	0.937	0.063	0.000
D52 Folate deficiency anaemia	0.000	0.065	0.935
N48.2 Other inflammatory disorders of penis	0.934	0.066	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.070	0.930
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.922	0.078	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.922	0.078	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.922	0.078	0.000
N48.1 Balanoposthitis	0.921	0.079	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.915	0.085	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.085	0.915
D52.9 Folate deficiency anaemia, unspecified	0.000	0.088	0.912
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.911	0.089	0.000
D69.4 Other primary thrombocytopenia	0.000	0.090	0.910
L40 Psoriasis	0.906	0.094	0.000
D68.8 Other specified coagulation defects	0.000	0.095	0.905
C34 Malignant neoplasm of bronchus and lung	0.000	0.097	0.903
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.097	0.903
C34.9 Bronchus or lung, unspecified	0.000	0.100	0.900
C82.0 Small cleaved cell, follicular	0.897	0.103	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.894	0.106	0.000
C34.3 Lower lobe, bronchus or lung	0.000	0.107	0.893
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.886	0.114	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.872	0.128	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.871	0.129	0.000
N48.5 Ulcer of penis	0.862	0.138	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.140	0.860
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.857	0.143	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.853	0.147	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.151	0.849
M05.8 Other seropositive rheumatoid arthritis	0.849	0.151	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.152	0.848
M06.4 Inflammatory polyarthropathy	0.847	0.153	0.000
N48.8 Other specified disorders of penis	0.847	0.153	0.000
N48.9 Disorder of penis, unspecified	0.845	0.155	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.158	0.842
L40.5 Arthropathic psoriasis	0.836	0.164	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.833	0.167	0.000
C82.3 Follicular lymphoma grade IIIa	0.831	0.169	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.829	0.171	0.000
M05.1 Rheumatoid lung disease	0.823	0.177	0.000
C34.2 Middle lobe, bronchus or lung	0.000	0.178	0.822
C82.2 Large cell, follicular	0.819	0.181	0.000
J33.8 Other polyp of sinus	0.817	0.183	0.000
C34.1 Upper lobe, bronchus or lung	0.000	0.184	0.816
D68.0 Von Willebrand's disease	0.000	0.184	0.816
M06.30 Rheumatoid nodule (Multiple sites)	0.815	0.185	0.000
D51 Vitamin B12 deficiency anaemia	0.000	0.190	0.810
M45 Ankylosing spondylitis	0.807	0.193	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.804	0.196	0.000
M08 Juvenile arthritis	0.803	0.197	0.000
C34.0 Main bronchus	0.000	0.204	0.796
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.791	0.209	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.791	0.209	0.000
D68.9 Coagulation defect, unspecified	0.000	0.209	0.791
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.790	0.210	0.000
D68.6 Other Thrombophilia	0.000	0.210	0.790
D86.1 Sarcoidosis of lymph nodes	0.000	0.210	0.790
E03.9 Hypothyroidism, unspecified	0.786	0.214	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.784	0.216	0.000
M06.33 Rheumatoid nodule (Forearm)	0.784	0.216	0.000
K90.8 Other intestinal malabsorption	0.000	0.219	0.780
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.770	0.230	0.000
M07 Psoriatic and enteropathic arthropathies	0.768	0.232	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.762	0.238	0.000
D86.3 Sarcoidosis of skin	0.000	0.239	0.761
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.761	0.239	0.000
C82.4 Follicular lymphoma grade IIIb	0.754	0.246	0.000
M14 Arthropathies in other diseases classified elsewhere	0.753	0.247	0.000
L40.4 Guttate psoriasis	0.752	0.248	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.751	0.249	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.746	0.254	0.000
D67 Hereditary factor IX deficiency	0.000	0.260	0.740
M06.8 Other specified rheumatoid arthritis	0.740	0.260	0.000
N44 Torsion of testis	0.731	0.269	0.000
J33.1 Polypoid sinus degeneration	0.730	0.270	0.000
C34.8 Overlapping lesion of bronchus and lung	0.000	0.273	0.727
N51 Disorders of male genital organs in diseases classified elsewhere	0.726	0.274	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.275	0.725
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.275	0.724
D68.4 Acquired coagulation factor deficiency	0.000	0.276	0.723
N48.4 Impotence of organic origin	0.721	0.279	0.000
D89.1 Cryoglobulinaemia	0.000	0.279	0.721
M12 Other specific arthropathies	0.720	0.280	0.000
L40.8 Other psoriasis	0.719	0.281	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.717	0.283	0.000
M05.0 Felty's syndrome	0.717	0.283	0.000
D81 Combined immunodeficiencies	0.000	0.283	0.717
N49.2 Inflammatory disorders of scrotum	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.716	0.284	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.716	0.284	0.000
M06.38 Rheumatoid nodule (Other)	0.716	0.284	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.716	0.284	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.716	0.284	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.715	0.285	0.000
C21.1 Anal canal	0.714	0.286	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.713	0.286	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.713	0.286	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.713	0.286	0.000
N48.3 Priapism	0.713	0.287	0.000
C21.0 Anus, unspecified	0.712	0.288	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.711	0.289	0.000
D53 Other nutritional anaemias	0.000	0.289	0.711
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.710	0.290	0.000
C21 Malignant neoplasm of anus and anal canal	0.708	0.292	0.000
M05.2 Rheumatoid vasculitis	0.707	0.293	0.000
D69.8 Other specified haemorrhagic conditions	0.000	0.294	0.706
C82.6 Cutaneous follicle centre lymphoma	0.703	0.297	0.000
C82.5 Diffuse follicle centre lymphoma	0.703	0.297	0.000
D82 Immunodeficiency associated with other major defects	0.000	0.298	0.702
K90.3 Pancreatic steatorrhoea	0.000	0.298	0.702
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.298	0.702
K90.1 Tropical sprue	0.000	0.298	0.702
D89.3 Immune reconstitution syndrome	0.000	0.298	0.701
M11 Other crystal arthropathies	0.701	0.299	0.000
D83 Common variable immunodeficiency	0.000	0.310	0.689
M06.1 Adult-onset Still's disease	0.689	0.310	0.000
D84 Other immunodeficiencies	0.000	0.311	0.689
D68.1 Hereditary factor XI deficiency	0.000	0.311	0.689
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.313	0.687
D69.5 Secondary thrombocytopenia	0.000	0.318	0.682
E05.5 Thyroid crisis or storm	0.001	0.323	0.677
E05.4 Thyrotoxicosis factitia	0.001	0.323	0.677
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.001	0.323	0.677
D52.8 Other folate deficiency anaemias	0.000	0.329	0.670
D52.1 Drug-induced folate deficiency anaemia	0.000	0.329	0.670
D52.0 Dietary folate deficiency anaemia	0.000	0.329	0.670
M08.0 Juvenile rheumatoid arthritis	0.667	0.333	0.000
D86.8 Sarcoidosis of other and combined sites	0.000	0.333	0.667
D68.2 Hereditary deficiency of other clotting factors	0.000	0.337	0.663
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.662	0.337	0.000
D69.1 Qualitative platelet defects	0.000	0.340	0.660
D69.2 Other nonthrombocytopenic purpura	0.000	0.345	0.655
M05.19 Rheumatoid lung disease (Site unspecified)	0.655	0.345	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.001	0.345	0.654
D69.0 Allergic purpura	0.000	0.348	0.652
M14.6 Neuropathic arthropathy	0.651	0.349	0.000
L40.1 Generalised pustular psoriasis	0.650	0.350	0.000
L40.2 Acrodermatitis continua	0.649	0.350	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.649	0.351	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.359	0.641
D50 Iron deficiency anaemia	0.000	0.363	0.637
L40.0 Psoriasis vulgaris	0.633	0.367	0.000
M07.3 Other psoriatic arthropathies	0.625	0.375	0.000
N49.8 Inflammatory disorders of other specified male genital organs	0.624	0.376	0.000
G37 Other demyelinating diseases of central nervous system	0.000	0.377	0.623
L40.3 Pustulosis palmaris et plantaris	0.619	0.381	0.000
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens	0.611	0.389	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.609	0.391	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.609	0.391	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.609	0.391	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.609	0.391	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.609	0.391	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.609	0.391	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.609	0.391	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.609	0.391	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.607	0.393	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.607	0.393	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.607	0.393	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.607	0.393	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.607	0.393	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.607	0.393	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.607	0.393	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.606	0.393	0.000
N49.9 Inflammatory disorder of unspecified male genital organ	0.594	0.406	0.000
N49.0 Inflammatory disorders of seminal vesicle	0.594	0.406	0.000
D55-D59 Haemolytic anaemias	0.000	0.406	0.593
M05.18 Rheumatoid lung disease (Other)	0.590	0.410	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.590	0.410	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.590	0.410	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.590	0.410	0.000
M05.14 Rheumatoid lung disease (Hand)	0.590	0.410	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.590	0.410	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.590	0.410	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.590	0.410	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.416	0.583
D51.2 Transcobalamin II deficiency	0.000	0.419	0.581
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.419	0.581
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.579	0.421	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.579	0.421	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.579	0.421	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.579	0.421	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.579	0.421	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.579	0.421	0.000
M08.9 Juvenile arthritis, unspecified	0.576	0.424	0.000
M08.8 Other juvenile arthritis	0.576	0.424	0.000
M08.4 Pauciarticular juvenile arthritis	0.576	0.424	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.576	0.424	0.000
M08.1 Juvenile ankylosing spondylitis	0.576	0.424	0.000
E05.8 Other thyrotoxicosis	0.001	0.425	0.574
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.574	0.426	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.573	0.427	0.000
M08.2 Juvenile arthritis with systemic onset	0.569	0.431	0.000
N42 Other disorders of prostate	0.568	0.432	0.000
D80 Immunodeficiency with predominantly antibody defects	0.000	0.437	0.562
N51.2 Balanitis in diseases classified elsewhere	0.561	0.438	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.441	0.559
M08.00 Juvenile rheumatoid arthritis (Multiple sites)	0.558	0.442	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.553	0.447	0.000
M07.5 Arthropathy in ulcerative colitis	0.551	0.449	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.551	0.449	0.000
M07.2 Psoriatic spondylitis	0.551	0.449	0.000
M07.1 Arthritis mutilans	0.551	0.449	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.551	0.449	0.000
D84.1 Defects in the complement system	0.000	0.450	0.550
M14.2 Diabetic arthropathy	0.547	0.452	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.544	0.456	0.000
D53.9 Nutritional anaemia, unspecified	0.000	0.460	0.540
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.540	0.460	0.000
M14.4 Arthropathy in amyloidosis	0.540	0.460	0.000
M14.3 Lipoid dermatoarthritis	0.540	0.460	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.540	0.460	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.540	0.460	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.539	0.460	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.538	0.462	0.000
M12.3 Palindromic rheumatism	0.536	0.463	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.466	0.534
M12.5 Traumatic arthropathy	0.532	0.467	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.530	0.470	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.530	0.470	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.530	0.470	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.530	0.470	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.530	0.470	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.530	0.470	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.530	0.470	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.530	0.470	0.000
D82.1 Di George's syndrome	0.000	0.471	0.528
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.473	0.527
C21.8 Overlapping lesion of rectum, anus and anal canal	0.527	0.473	0.000
D50.9 Iron deficiency anaemia, unspecified	0.000	0.475	0.525
N51.8 Other disorders of male genital organs in diseases classified elsewhere	0.521	0.479	0.000
N51.1 Disorders of testis and epididymis in diseases classified elsewhere	0.521	0.479	0.000
N51.0 Disorders of prostate in diseases classified elsewhere	0.521	0.479	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.519	0.480	0.000
M12.4 Intermittent hydrarthrosis	0.516	0.484	0.000
M12.1 Kaschin-Beck disease	0.516	0.484	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.516	0.484	0.000
M07.6 Other enteropathic arthropathies	0.516	0.484	0.000
N45 Orchitis and epididymitis	0.516	0.484	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.485	0.515
M06.29 Rheumatoid bursitis (Site unspecified)	0.514	0.486	0.000
M06.28 Rheumatoid bursitis (Other)	0.514	0.486	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.514	0.486	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.514	0.486	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.514	0.486	0.000
M06.24 Rheumatoid bursitis (Hand)	0.514	0.486	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.514	0.486	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.514	0.486	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.514	0.486	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.514	0.486	0.000
M05.09 Felty's syndrome (Site unspecified)	0.514	0.486	0.000
M05.08 Felty's syndrome (Other)	0.514	0.486	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.514	0.486	0.000
M05.06 Felty's syndrome (Lower leg)	0.514	0.486	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.514	0.486	0.000
M05.04 Felty's syndrome (Hand)	0.514	0.486	0.000
M05.03 Felty's syndrome (Forearm)	0.514	0.486	0.000
M05.02 Felty's syndrome (Upper arm)	0.514	0.486	0.000
M05.01 Felty's syndrome (Shoulder region)	0.514	0.486	0.000
M05.00 Felty's syndrome (Multiple sites)	0.514	0.486	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.514	0.486	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.514	0.486	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.514	0.486	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.514	0.486	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.514	0.486	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.514	0.486	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.514	0.486	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.514	0.486	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.514	0.486	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.514	0.486	0.000
D81.9 Combined immunodeficiency, unspecified	0.000	0.486	0.514
D81.8 Other combined immunodeficiencies	0.000	0.486	0.514
D81.7 Major histocompatibility complex class II deficiency	0.000	0.486	0.514
D81.6 Major histocompatibility complex class I deficiency	0.000	0.486	0.514
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.486	0.514
D81.4 Nezelof's syndrome	0.000	0.486	0.514
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.486	0.514
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.486	0.514
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.486	0.514
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.486	0.514
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.514	0.486	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.514	0.486	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.514	0.486	0.000
M09.0 Juvenile arthritis in psoriasis	0.514	0.486	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.000	0.487	0.513
M12.2 Villonodular synovitis (pigmented)	0.513	0.487	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.512	0.488	0.000
D53.8 Other specified nutritional anaemias	0.000	0.490	0.510
D53.2 Scorbutic anaemia	0.000	0.490	0.510
D53.0 Protein deficiency anaemia	0.000	0.490	0.510
C21.2 Cloacogenic zone	0.507	0.492	0.000
M05.28 Rheumatoid vasculitis (Other)	0.507	0.493	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.507	0.493	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.507	0.493	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.507	0.493	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.507	0.493	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.507	0.493	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.507	0.493	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.507	0.493	0.000
M11.9 Crystal arthropathy, unspecified	0.505	0.494	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.496	0.503
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.496	0.503
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.496	0.503
D82.2 Immunodeficiency with short-limbed stature	0.000	0.496	0.503
D82.0 Wiskott-Aldrich syndrome	0.000	0.496	0.503
M11.1 Familial chondrocalcinosis	0.503	0.497	0.000
M11.0 Hydroxyapatite deposition disease	0.503	0.497	0.000
M11.2 Other chondrocalcinosis	0.503	0.497	0.000
D60-D64 Aplastic and other anaemias	0.000	0.497	0.503
D66 Hereditary factor VIII deficiency	0.000	0.501	0.498
D69.9 Haemorrhagic condition, unspecified	0.000	0.502	0.498
M08.09 Juvenile rheumatoid arthritis (Site unspecified)	0.498	0.502	0.000
G36 Other acute disseminated demyelination	0.000	0.505	0.495
D83.8 Other common variable immunodeficiencies	0.000	0.505	0.494
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.505	0.494
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.505	0.494
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.505	0.494
M06.19 Adult-onset Still's disease (Site unspecified)	0.494	0.506	0.000
M06.18 Adult-onset Still's disease (Other)	0.494	0.506	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.494	0.506	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.494	0.506	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.494	0.506	0.000
M06.14 Adult-onset Still's disease (Hand)	0.494	0.506	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.494	0.506	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.494	0.506	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.494	0.506	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.000	0.506	0.494
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.506	0.494
M13 Other arthritis	0.491	0.509	0.000
D84.8 Other specified immunodeficiencies	0.000	0.509	0.490
M11.8 Other specified crystal arthropathies	0.485	0.515	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.484	0.516	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.483	0.517	0.000
D59 Acquired haemolytic anaemia	0.000	0.520	0.480
M08.08 Juvenile rheumatoid arthritis (Other)	0.478	0.522	0.000
M08.07 Juvenile rheumatoid arthritis (Ankle and foot)	0.478	0.522	0.000
M08.06 Juvenile rheumatoid arthritis (Lower leg)	0.478	0.522	0.000
M08.05 Juvenile rheumatoid arthritis (Pelvic region and thigh)	0.478	0.522	0.000
M08.04 Juvenile rheumatoid arthritis (Hand)	0.478	0.522	0.000
M08.03 Juvenile rheumatoid arthritis (Forearm)	0.478	0.522	0.000
M08.02 Juvenile rheumatoid arthritis (Upper arm)	0.478	0.522	0.000
M08.01 Juvenile rheumatoid arthritis (Shoulder region)	0.478	0.522	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.524	0.476
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.470	0.530	0.000
M07.38 Other psoriatic arthropathies (Other)	0.469	0.531	0.000
D83.9 Common variable immunodeficiency, unspecified	0.000	0.533	0.467
M06.10 Adult-onset Still's disease (Multiple sites)	0.467	0.533	0.000
N42.2 Atrophy of prostate	0.463	0.537	0.000
D50.1 Sideropenic dysphagia	0.000	0.538	0.462
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.541	0.458
M07.33 Other psoriatic arthropathies (Forearm)	0.448	0.551	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.448	0.551	0.000
G37.5 Concentric sclerosis [Balo]	0.000	0.553	0.447
G37.4 Subacute necrotising myelitis	0.000	0.553	0.447
G37.2 Central pontine myelinolysis	0.000	0.553	0.447
G37.1 Central demyelination of corpus callosum	0.000	0.553	0.447
G37.0 Diffuse sclerosis	0.000	0.553	0.447
D61 Other aplastic anaemias	0.000	0.561	0.439
L40-L45 Papulosquamous disorders	0.437	0.563	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.432	0.568	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.570	0.430
D55 Anaemia due to enzyme disorders	0.000	0.574	0.425
N42.3 Dysplasia of prostate	0.424	0.576	0.000
N40 Hyperplasia of prostate	0.422	0.578	0.000
D59.1 Other autoimmune haemolytic anaemias	0.000	0.578	0.422
M13.1 Monoarthritis, not elsewhere classified	0.419	0.581	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.586	0.414
M12.30 Palindromic rheumatism (Multiple sites)	0.414	0.586	0.000
M08.19 Juvenile ankylosing spondylitis (Site unspecified)	0.413	0.587	0.000
M08.18 Juvenile ankylosing spondylitis (Other)	0.413	0.587	0.000
M08.17 Juvenile ankylosing spondylitis (Ankle and foot)	0.413	0.587	0.000
M08.16 Juvenile ankylosing spondylitis (Lower leg)	0.413	0.587	0.000
M08.15 Juvenile ankylosing spondylitis (Pelvic region and thigh)	0.413	0.587	0.000
M08.14 Juvenile ankylosing spondylitis (Hand)	0.413	0.587	0.000
M08.13 Juvenile ankylosing spondylitis (Forearm)	0.413	0.587	0.000
M08.12 Juvenile ankylosing spondylitis (Upper arm)	0.413	0.587	0.000
M08.11 Juvenile ankylosing spondylitis (Shoulder region)	0.413	0.587	0.000
M08.10 Juvenile ankylosing spondylitis (Multiple sites)	0.413	0.587	0.000
M08.39 Juvenile polyarthritis (seronegative) (Site unspecified)	0.413	0.587	0.000
M08.38 Juvenile polyarthritis (seronegative) (Other)	0.413	0.587	0.000
M08.37 Juvenile polyarthritis (seronegative) (Ankle and foot)	0.413	0.587	0.000
M08.36 Juvenile polyarthritis (seronegative) (Lower leg)	0.413	0.587	0.000
M08.35 Juvenile polyarthritis (seronegative) (Pelvic region and thigh)	0.413	0.587	0.000
M08.34 Juvenile polyarthritis (seronegative) (Hand)	0.413	0.587	0.000
M08.33 Juvenile polyarthritis (seronegative) (Forearm)	0.413	0.587	0.000
M08.32 Juvenile polyarthritis (seronegative) (Upper arm)	0.413	0.587	0.000
M08.31 Juvenile polyarthritis (seronegative) (Shoulder region)	0.413	0.587	0.000
M08.30 Juvenile polyarthritis (seronegative) (Multiple sites)	0.413	0.587	0.000
M08.49 Pauciarticular juvenile arthritis (Site unspecified)	0.413	0.587	0.000
M08.48 Pauciarticular juvenile arthritis (Other)	0.413	0.587	0.000
M08.47 Pauciarticular juvenile arthritis (Ankle and foot)	0.413	0.587	0.000
M08.46 Pauciarticular juvenile arthritis (Lower leg)	0.413	0.587	0.000
M08.45 Pauciarticular juvenile arthritis (Pelvic region and thigh)	0.413	0.587	0.000
M08.44 Pauciarticular juvenile arthritis (Hand)	0.413	0.587	0.000
M08.43 Pauciarticular juvenile arthritis (Forearm)	0.413	0.587	0.000
M08.42 Pauciarticular juvenile arthritis (Upper arm)	0.413	0.587	0.000
M08.41 Pauciarticular juvenile arthritis (Shoulder region)	0.413	0.587	0.000
M08.40 Pauciarticular juvenile arthritis (Multiple sites)	0.413	0.587	0.000
M08.89 Other juvenile arthritis (Site unspecified)	0.413	0.587	0.000
M08.88 Other juvenile arthritis (Other)	0.413	0.587	0.000
M08.87 Other juvenile arthritis (Ankle and foot)	0.413	0.587	0.000
M08.86 Other juvenile arthritis (Lower leg)	0.413	0.587	0.000
M08.85 Other juvenile arthritis (Pelvic region and thigh)	0.413	0.587	0.000
M08.84 Other juvenile arthritis (Hand)	0.413	0.587	0.000
M08.83 Other juvenile arthritis (Forearm)	0.413	0.587	0.000
M08.82 Other juvenile arthritis (Upper arm)	0.413	0.587	0.000
M08.81 Other juvenile arthritis (Shoulder region)	0.413	0.587	0.000
M08.80 Other juvenile arthritis (Multiple sites)	0.413	0.587	0.000
M08.99 Juvenile arthritis, unspecified (Site unspecified)	0.413	0.587	0.000
M08.98 Juvenile arthritis, unspecified (Other)	0.413	0.587	0.000
M08.97 Juvenile arthritis, unspecified (Ankle and foot)	0.413	0.587	0.000
M08.96 Juvenile arthritis, unspecified (Lower leg)	0.413	0.587	0.000
M08.95 Juvenile arthritis, unspecified (Pelvic region and thigh)	0.413	0.587	0.000
M08.94 Juvenile arthritis, unspecified (Hand)	0.413	0.587	0.000
M08.93 Juvenile arthritis, unspecified (Forearm)	0.413	0.587	0.000
M08.92 Juvenile arthritis, unspecified (Upper arm)	0.413	0.587	0.000
M08.91 Juvenile arthritis, unspecified (Shoulder region)	0.413	0.587	0.000
M08.90 Juvenile arthritis, unspecified (Multiple sites)	0.413	0.587	0.000
N46 Male infertility	0.410	0.589	0.001
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.409	0.590	0.000
M12.24 Villonodular synovitis (pigmented) (Hand)	0.408	0.592	0.000
M08.28 Juvenile arthritis with systemic onset (Other)	0.408	0.592	0.000
M08.27 Juvenile arthritis with systemic onset (Ankle and foot)	0.408	0.592	0.000
M08.26 Juvenile arthritis with systemic onset (Lower leg)	0.408	0.592	0.000
M08.25 Juvenile arthritis with systemic onset (Pelvic region and thigh)	0.408	0.592	0.000
M08.24 Juvenile arthritis with systemic onset (Hand)	0.408	0.592	0.000
M08.23 Juvenile arthritis with systemic onset (Forearm)	0.408	0.592	0.000
M08.22 Juvenile arthritis with systemic onset (Upper arm)	0.408	0.592	0.000
M08.21 Juvenile arthritis with systemic onset (Shoulder region)	0.408	0.592	0.000
M08.20 Juvenile arthritis with systemic onset (Multiple sites)	0.408	0.592	0.000
E03 Other hypothyroidism	0.316	0.592	0.092
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.596	0.403
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.596	0.403
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.596	0.403
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.596	0.403
M08.29 Juvenile arthritis with systemic onset (Site unspecified)	0.401	0.599	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.401	0.599	0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess	0.399	0.601	0.000
M12.57 Traumatic arthropathy (Ankle and foot)	0.398	0.602	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.001	0.603	0.396
D57 Sickle-cell disorders	0.000	0.604	0.395
D61.9 Aplastic anaemia, unspecified	0.000	0.605	0.395
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.395	0.605	0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.395	0.605	0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.395	0.605	0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.395	0.605	0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.395	0.605	0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.395	0.605	0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.395	0.605	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations