TreeWAS – Variant ID: rs28752896

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
R31 Unspecified haematuria	1.000	0.000	0.000
E03 Other hypothyroidism	0.000	0.002	0.998
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.004	0.996
L40.0 Psoriasis vulgaris	0.996	0.004	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.005	0.995
E00-E07 Disorders of thyroid gland	0.000	0.005	0.995
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.019	0.981
M45 Ankylosing spondylitis	0.968	0.032	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.959	0.041	0.000
M07.3 Other psoriatic arthropathies	0.917	0.083	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.910	0.090	0.000
L40.4 Guttate psoriasis	0.906	0.094	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.094	0.906
M07.39 Other psoriatic arthropathies (Site unspecified)	0.901	0.099	0.000
G35 Multiple sclerosis	0.000	0.109	0.891
M35.0 Sicca syndrome [Sjogren]	0.000	0.136	0.864
E07 Other disorders of thyroid	0.000	0.136	0.864
M07.36 Other psoriatic arthropathies (Lower leg)	0.854	0.146	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.844	0.156	0.000
E03.8 Other specified hypothyroidism	0.000	0.198	0.802
M45.X2 Ankylosing spondylitis (Cervical region)	0.781	0.219	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.781	0.219	0.000
L40.8 Other psoriasis	0.777	0.223	0.000
K90 Intestinal malabsorption	0.000	0.227	0.773
E07.8 Other specified disorders of thyroid	0.000	0.229	0.771
L40.1 Generalised pustular psoriasis	0.761	0.239	0.000
M07.38 Other psoriatic arthropathies (Other)	0.757	0.243	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.741	0.259	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.281	0.718
L40.2 Acrodermatitis continua	0.717	0.283	0.000
E03.5 Myxoedema coma	0.000	0.284	0.716
E03.4 Atrophy of thyroid (acquired)	0.000	0.284	0.716
E03.3 Postinfectious hypothyroidism	0.000	0.284	0.716
E05.5 Thyroid crisis or storm	0.000	0.286	0.714
E05.4 Thyrotoxicosis factitia	0.000	0.286	0.714
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.286	0.714
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.287	0.713
E00 Congenital iodine-deficiency syndrome	0.000	0.287	0.713
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.694	0.306	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.694	0.306	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.694	0.306	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.694	0.306	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.694	0.306	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.694	0.306	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.686	0.314	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.316	0.684
M45.X6 Ankylosing spondylitis (Lumbar region)	0.672	0.328	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.657	0.342	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.657	0.342	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.345	0.655
E03.1 Congenital hypothyroidism without goitre	0.000	0.349	0.651
L40.3 Pustulosis palmaris et plantaris	0.639	0.361	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.379	0.621
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.380	0.620
E07.1 Dyshormogenetic goitre	0.000	0.380	0.619
E07.0 Hypersecretion of calcitonin	0.000	0.380	0.619
E07.9 Disorder of thyroid, unspecified	0.000	0.382	0.618
K90.8 Other intestinal malabsorption	0.000	0.398	0.602
E05.8 Other thyrotoxicosis	0.000	0.431	0.569
K90.3 Pancreatic steatorrhoea	0.000	0.446	0.554
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.446	0.554
K90.1 Tropical sprue	0.000	0.446	0.554
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.488	0.511
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.488	0.511
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.488	0.511
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.488	0.511
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.488	0.511
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.488	0.511
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.488	0.511
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.488	0.511
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.493	0.507
L40-L45 Papulosquamous disorders	0.473	0.526	0.000
M07 Psoriatic and enteropathic arthropathies	0.436	0.564	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.573	0.427
L41 Parapsoriasis	0.370	0.630	0.000
L42 Pityriasis rosea	0.360	0.640	0.000
L44 Other papulosquamous disorders	0.342	0.658	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.340	0.660	0.000
E06 Thyroiditis	0.001	0.666	0.333
M07.5 Arthropathy in ulcerative colitis	0.313	0.687	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.313	0.687	0.000
M07.2 Psoriatic spondylitis	0.313	0.687	0.000
M07.1 Arthritis mutilans	0.313	0.687	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.313	0.687	0.000
G36 Other acute disseminated demyelination	0.000	0.687	0.313
L43 Lichen planus	0.306	0.694	0.000
L41.1 Pityriasis lichenoides chronica	0.296	0.703	0.000
M07.6 Other enteropathic arthropathies	0.289	0.711	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.723	0.277
L41.9 Parapsoriasis, unspecified	0.266	0.734	0.000
L41.8 Other parapsoriasis	0.266	0.734	0.000
L41.5 Retiform parapsoriasis	0.266	0.734	0.000
L41.4 Large plaque parapsoriasis	0.266	0.734	0.000
L41.3 Small plaque parapsoriasis	0.266	0.734	0.000
L41.2 Lymphomatoid papulosis	0.266	0.734	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.266	0.734	0.000
G30-G32 Other degenerative diseases of the nervous system	0.000	0.735	0.265
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.736	0.264
Chapter VI Diseases of the nervous system	0.000	0.738	0.262
G31.2 Degeneration of nervous system due to alcohol	0.000	0.745	0.255
L44.0 Pityriasis rubra pilaris	0.248	0.752	0.000
E06.3 Autoimmune thyroiditis	0.000	0.754	0.246
L44.9 Papulosquamous disorder, unspecified	0.245	0.754	0.000
L44.8 Other specified papulosquamous disorders	0.245	0.754	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.245	0.754	0.000
L44.3 Lichen ruber moniliformis	0.245	0.754	0.000
L44.2 Lichen striatus	0.245	0.754	0.000
L44.1 Lichen nitidus	0.245	0.754	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.000	0.760	0.239
E06.4 Drug-induced thyroiditis	0.001	0.761	0.239
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.001	0.761	0.239
E06.0 Acute thyroiditis	0.001	0.761	0.239
G70-G73 Diseases of myoneural junction and muscle	0.000	0.761	0.239
D69.6 Thrombocytopenia, unspecified	0.000	0.764	0.236
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.766	0.234
G72 Other myopathies	0.000	0.767	0.233
G36.0 Neuromyelitis optica [Devic]	0.000	0.769	0.231
L43.8 Other lichen planus	0.225	0.774	0.000
E27 Other disorders of adrenal gland	0.000	0.776	0.224
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.224	0.776	0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.224	0.776	0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.224	0.776	0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.224	0.776	0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.224	0.776	0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.224	0.776	0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.224	0.776	0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.224	0.776	0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.224	0.776	0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.224	0.776	0.000
M07.19 Arthritis mutilans (Site unspecified)	0.224	0.776	0.000
M07.18 Arthritis mutilans (Other)	0.224	0.776	0.000
M07.17 Arthritis mutilans (Ankle and foot)	0.224	0.776	0.000
M07.16 Arthritis mutilans (Lower leg)	0.224	0.776	0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.224	0.776	0.000
M07.14 Arthritis mutilans (Hand)	0.224	0.776	0.000
M07.13 Arthritis mutilans (Forearm)	0.224	0.776	0.000
M07.12 Arthritis mutilans (Upper arm)	0.224	0.776	0.000
M07.11 Arthritis mutilans (Shoulder region)	0.224	0.776	0.000
M07.10 Arthritis mutilans (Multiple sites)	0.224	0.776	0.000
M07.29 Psoriatic spondylitis (Site unspecified)	0.224	0.776	0.000
M07.28 Psoriatic spondylitis (Other)	0.224	0.776	0.000
M07.27 Psoriatic spondylitis (Ankle and foot)	0.224	0.776	0.000
M07.26 Psoriatic spondylitis (Lower leg)	0.224	0.776	0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.224	0.776	0.000
M07.24 Psoriatic spondylitis (Hand)	0.224	0.776	0.000
M07.23 Psoriatic spondylitis (Forearm)	0.224	0.776	0.000
M07.22 Psoriatic spondylitis (Upper arm)	0.224	0.776	0.000
M07.21 Psoriatic spondylitis (Shoulder region)	0.224	0.776	0.000
M07.20 Psoriatic spondylitis (Multiple sites)	0.224	0.776	0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.224	0.776	0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.224	0.776	0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.224	0.776	0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.224	0.776	0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.224	0.776	0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.224	0.776	0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.224	0.776	0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.224	0.776	0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.224	0.776	0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.224	0.776	0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.224	0.776	0.000
M07.58 Arthropathy in ulcerative colitis (Other)	0.224	0.776	0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.224	0.776	0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.224	0.776	0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.224	0.776	0.000
M07.54 Arthropathy in ulcerative colitis (Hand)	0.224	0.776	0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.224	0.776	0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.224	0.776	0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.224	0.776	0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.224	0.776	0.000
G36.9 Acute disseminated demyelination, unspecified	0.000	0.776	0.224
G36.8 Other specified acute disseminated demyelination	0.000	0.776	0.224
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.776	0.224
G09 Sequelae of inflammatory diseases of central nervous system	0.000	0.779	0.221
G72.9 Myopathy, unspecified	0.000	0.779	0.221
L43.3 Subacute (active) lichen planus	0.220	0.780	0.000
L43.2 Lichenoid drug reaction	0.220	0.780	0.000
L43.1 Bullous lichen planus	0.220	0.780	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.780	0.219
G30 Alzheimer's disease	0.000	0.780	0.219
G80-G83 Cerebral palsy and other paralytic syndromes	0.000	0.782	0.218
E04 Other non-toxic goitre	0.000	0.789	0.211
L43.0 Hypertrophic lichen planus	0.208	0.791	0.000
M07.68 Other enteropathic arthropathies (Other)	0.207	0.792	0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.207	0.792	0.000
M07.66 Other enteropathic arthropathies (Lower leg)	0.207	0.792	0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.207	0.792	0.000
M07.64 Other enteropathic arthropathies (Hand)	0.207	0.792	0.000
M07.63 Other enteropathic arthropathies (Forearm)	0.207	0.792	0.000
M07.62 Other enteropathic arthropathies (Upper arm)	0.207	0.792	0.000
M07.61 Other enteropathic arthropathies (Shoulder region)	0.207	0.792	0.000
M07.60 Other enteropathic arthropathies (Multiple sites)	0.207	0.792	0.000
G31.8 Other specified degenerative diseases of nervous system	0.000	0.793	0.207
G00 Bacterial meningitis, not elsewhere classified	0.000	0.800	0.199
G72.8 Other specified myopathies	0.000	0.803	0.197
G31.0 Circumscribed brain atrophy	0.000	0.806	0.194
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.806	0.194
G06 Intracranial and intraspinal abscess and granuloma	0.000	0.807	0.193
E27.2 Addisonian crisis	0.000	0.807	0.193
L43.9 Lichen planus, unspecified	0.193	0.807	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.811	0.189
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.813	0.187
G72.1 Alcoholic myopathy	0.000	0.814	0.186
G82 Paraplegia and tetraplegia	0.000	0.814	0.186
E06.5 Other chronic thyroiditis	0.001	0.815	0.184
M07.69 Other enteropathic arthropathies (Site unspecified)	0.184	0.816	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.818	0.182
G72.0 Drug-induced myopathy	0.000	0.819	0.181
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.820	0.180
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.000	0.822	0.178
G30.0 Alzheimer's disease with early onset	0.000	0.823	0.177
G82.1 Spastic paraplegia	0.000	0.823	0.177
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.000	0.828	0.172
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.000	0.828	0.172
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.000	0.828	0.172
G03 Meningitis due to other and unspecified causes	0.000	0.829	0.171
G83 Other paralytic syndromes	0.000	0.830	0.170
E04.0 Non-toxic diffuse goitre	0.000	0.831	0.169
G00.9 Bacterial meningitis, unspecified	0.000	0.831	0.169
G37 Other demyelinating diseases of central nervous system	0.000	0.831	0.169
E06.1 Subacute thyroiditis	0.001	0.832	0.167
G01 Meningitis in bacterial diseases classified elsewhere	0.000	0.832	0.168
G72.3 Periodic paralysis	0.000	0.833	0.167
G72.2 Myopathy due to other toxic agents	0.000	0.833	0.167
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.000	0.833	0.167
G30.1 Alzheimer's disease with late onset	0.000	0.834	0.166
G06.1 Intraspinal abscess and granuloma	0.000	0.836	0.163
E28 Ovarian dysfunction	0.000	0.837	0.163
G30.8 Other Alzheimer's disease	0.000	0.837	0.163
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.000	0.838	0.161
E27.5 Adrenomedullary hyperfunction	0.000	0.839	0.161
E27.0 Other adrenocortical overactivity	0.000	0.839	0.161
G83.4 Cauda equina syndrome	0.000	0.840	0.160
G30.9 Alzheimer's disease, unspecified	0.000	0.841	0.159
E20 Hypoparathyroidism	0.000	0.842	0.158
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.000	0.842	0.157
G81 Hemiplegia	0.000	0.843	0.157
G72.4 Inflammatory myopathy, not elsewhere classified	0.000	0.848	0.152
E04.8 Other specified non-toxic goitre	0.000	0.848	0.151
E27.8 Other specified disorders of adrenal gland	0.000	0.849	0.151
E06.9 Thyroiditis, unspecified	0.001	0.850	0.149
E28.3 Primary ovarian failure	0.000	0.850	0.150
M05-M14 Inflammatory polyarthropathies	0.146	0.854	0.000
G00.1 Pneumococcal meningitis	0.000	0.854	0.146
G71 Primary disorders of muscles	0.000	0.855	0.145
G06.0 Intracranial abscess and granuloma	0.000	0.856	0.144
G00.8 Other bacterial meningitis	0.000	0.857	0.143
G00.3 Staphylococcal meningitis	0.000	0.857	0.143
G00.2 Streptococcal meningitis	0.000	0.857	0.143
G00.0 Haemophilus meningitis	0.000	0.857	0.143
G82.5 Tetraplegia, unspecified	0.000	0.858	0.142
E20.9 Hypoparathyroidism, unspecified	0.000	0.859	0.141
G83.9 Paralytic syndrome, unspecified	0.000	0.859	0.141
G80 Infantile cerebral palsy	0.000	0.859	0.141
G82.4 Spastic tetraplegia	0.000	0.861	0.139
M05 Seropositive rheumatoid arthritis	0.139	0.861	0.000
M35 Other systemic involvement of connective tissue	0.000	0.864	0.136
D69 Purpura and other haemorrhagic conditions	0.000	0.865	0.135
G02.0 Meningitis in viral diseases classified elsewhere	0.000	0.865	0.134
G12 Spinal muscular atrophy and related syndromes	0.000	0.866	0.134
M05.9 Seropositive rheumatoid arthritis, unspecified	0.134	0.866	0.000
G82.3 Flaccid tetraplegia	0.000	0.867	0.133
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.869	0.131
E32 Diseases of thymus	0.000	0.869	0.131
E31 Polyglandular dysfunction	0.000	0.869	0.131
E30 Disorders of puberty, not elsewhere classified	0.000	0.869	0.131
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.869	0.130
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.000	0.872	0.128
G02.1 Meningitis in mycoses	0.000	0.872	0.128
G06.2 Extradural and subdural abscess, unspecified	0.000	0.873	0.126
G70 Myasthenia gravis and other myoneural disorders	0.000	0.874	0.125
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.876	0.124
E24 Cushing's syndrome	0.000	0.876	0.124
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.000	0.877	0.123
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.000	0.877	0.123
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.000	0.877	0.123
G73.7 Myopathy other diseases classified elsewhere	0.000	0.877	0.123
G73.6 Myopathy in metabolic diseases	0.000	0.877	0.123
G73.5 Myopathy in endocrine diseases	0.000	0.877	0.123
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere	0.000	0.877	0.123
G73.3 Myasthenic syndromes in other diseases classified elsewhere	0.000	0.877	0.123
G73.2 Other myasthenic syndromes in neoplastic disease	0.000	0.877	0.123
G73.1 Eaton-Lambert syndrome	0.000	0.877	0.123
G73.0 Myasthenic syndromes in endocrine diseases	0.000	0.877	0.123
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.000	0.877	0.123
G03.8 Meningitis due to other specified causes	0.000	0.877	0.123
G03.2 Benign recurrent meningitis [Mollaret]	0.000	0.877	0.123
G03.1 Chronic meningitis	0.000	0.877	0.123
G03.0 Nonpyogenic meningitis	0.000	0.877	0.123
G83.5 Locked-in syndrome	0.000	0.878	0.122
G83.0 Diplegia of upper limbs	0.000	0.878	0.122
G03.9 Meningitis, unspecified	0.000	0.878	0.122
G37.5 Concentric sclerosis [Balo]	0.000	0.878	0.121
G37.4 Subacute necrotising myelitis	0.000	0.878	0.121
G37.2 Central pontine myelinolysis	0.000	0.878	0.121
G37.1 Central demyelination of corpus callosum	0.000	0.878	0.121
G37.0 Diffuse sclerosis	0.000	0.878	0.121
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.122	0.878	0.000
G82.0 Flaccid paraplegia	0.000	0.879	0.121
G81.1 Spastic hemiplegia	0.000	0.879	0.121
G83.1 Monoplegia of lower limb	0.000	0.880	0.120
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.880	0.119
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.000	0.881	0.119
E25 Adrenogenital disorders	0.000	0.881	0.119
G11 Hereditary ataxia	0.000	0.883	0.117
E28.2 Polycystic ovarian syndrome	0.000	0.883	0.117
E28.9 Ovarian dysfunction, unspecified	0.000	0.883	0.117
E28.8 Other ovarian dysfunction	0.000	0.883	0.117
E28.1 Androgen excess	0.000	0.883	0.117
E28.0 Oestrogen excess	0.000	0.883	0.117
E20.8 Other hypoparathyroidism	0.000	0.886	0.114
E20.1 Pseudohypoparathyroidism	0.000	0.886	0.114
E20.0 Idiopathic hypoparathyroidism	0.000	0.886	0.114
G10 Huntington's disease	0.000	0.887	0.113
D69.4 Other primary thrombocytopenia	0.000	0.887	0.113
G81.0 Flaccid hemiplegia	0.000	0.888	0.112
G14 Postpolio syndrome	0.000	0.888	0.112
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.111	0.889	0.000
G71.3 Mitochondrial myopathy, not elsewhere classified	0.000	0.889	0.111
G12.2 Motor neuron disease	0.000	0.889	0.111
E23 Hypofunction and other disorders of pituitary gland	0.000	0.891	0.109
G80.0 Spastic cerebral palsy	0.000	0.891	0.109
G04 Encephalitis, myelitis and encephalomyelitis	0.000	0.891	0.109
M05.1 Rheumatoid lung disease	0.109	0.891	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.108	0.892	0.000
M08 Juvenile arthritis	0.108	0.892	0.000
M12 Other specific arthropathies	0.108	0.892	0.000
G83.3 Monoplegia, unspecified	0.000	0.893	0.107
D69.5 Secondary thrombocytopenia	0.000	0.893	0.107
M09 Juvenile arthritis in diseases classified elsewhere	0.105	0.895	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.104	0.896	0.000
G80.8 Other infantile cerebral palsy	0.000	0.896	0.104
G71.9 Primary disorder of muscle, unspecified	0.000	0.896	0.104
G71.8 Other primary disorders of muscles	0.000	0.896	0.104
G71.2 Congenital myopathies	0.000	0.896	0.104
G81.9 Hemiplegia, unspecified	0.000	0.898	0.102
D69.2 Other nonthrombocytopenic purpura	0.000	0.898	0.102
E27.9 Disorder of adrenal gland, unspecified	0.000	0.898	0.102
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.102	0.898	0.000
E40-E46 Malnutrition	0.000	0.899	0.101
G80.2 Infantile hemiplegia	0.000	0.899	0.101
G80.4 Ataxic cerebral palsy	0.000	0.899	0.101
G80.3 Dyskinetic cerebral palsy	0.000	0.899	0.101
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.101	0.899	0.000
N48.4 Impotence of organic origin	0.100	0.900	0.000
E24.2 Drug-induced Cushing's syndrome	0.000	0.900	0.100
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.100	0.900	0.000
E29 Testicular dysfunction	0.000	0.900	0.100
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.100	0.900	0.000
M05.0 Felty's syndrome	0.100	0.900	0.000
D69.0 Allergic purpura	0.000	0.901	0.099
N48 Other disorders of penis	0.099	0.901	0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere	0.000	0.901	0.099
E26 Hyperaldosteronism	0.000	0.901	0.099
M14 Arthropathies in other diseases classified elsewhere	0.099	0.901	0.000
N48.2 Other inflammatory disorders of penis	0.098	0.902	0.000
M35.8 Other specified systemic involvement of connective tissue	0.000	0.902	0.098
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.902	0.098
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.902	0.098
M35.5 Multifocal fibrosclerosis	0.000	0.902	0.098
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.902	0.098
M05.8 Other seropositive rheumatoid arthritis	0.097	0.903	0.000
D69.8 Other specified haemorrhagic conditions	0.000	0.903	0.097
G12.9 Spinal muscular atrophy, unspecified	0.000	0.903	0.096
G12.8 Other spinal muscular atrophies and related syndromes	0.000	0.903	0.096
G12.1 Other inherited spinal muscular atrophy	0.000	0.903	0.096
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]	0.000	0.903	0.096
G80.1 Spastic diplegia	0.000	0.904	0.096
G71.1 Myotonic disorders	0.000	0.904	0.096
E34 Other endocrine disorders	0.000	0.904	0.096
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.096	0.904	0.000
E23.2 Diabetes insipidus	0.000	0.904	0.096
M35.7 Hypermobility syndrome	0.000	0.905	0.095
M35.2 Behcet's disease	0.000	0.905	0.095
R94.3 Abnormal results of cardiovascular function studies	0.000	0.905	0.095
E16 Other disorders of pancreatic internal secretion	0.000	0.905	0.095
M05.2 Rheumatoid vasculitis	0.094	0.905	0.000
E30.9 Disorder of puberty, unspecified	0.000	0.906	0.094
E30.8 Other disorders of puberty	0.000	0.906	0.094
E30.1 Precocious puberty	0.000	0.906	0.094
E30.0 Delayed puberty	0.000	0.906	0.094
E31.9 Polyglandular dysfunction, unspecified	0.000	0.906	0.094
E31.8 Other polyglandular dysfunction	0.000	0.906	0.094
E31.1 Polyglandular hyperfunction	0.000	0.906	0.094
E31.0 Autoimmune polyglandular failure	0.000	0.906	0.094
E32.9 Disease of thymus, unspecified	0.000	0.906	0.094
E32.8 Other diseases of thymus	0.000	0.906	0.094
E32.1 Abscess of thymus	0.000	0.906	0.094
E32.0 Persistent hyperplasia of thymus	0.000	0.906	0.094
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.906	0.094
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.906	0.094
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.906	0.094
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.094	0.906	0.000
E15 Nondiabetic hypoglycaemic coma	0.000	0.906	0.094
E24.8 Other Cushing's syndrome	0.000	0.907	0.093
G62 Other polyneuropathies	0.000	0.907	0.093
D69.1 Qualitative platelet defects	0.000	0.908	0.092
G70.8 Other specified myoneural disorders	0.000	0.910	0.090
G70.2 Congenital and developmental myasthenia	0.000	0.910	0.090
G70.1 Toxic myoneural disorders	0.000	0.910	0.090
G11.4 Hereditary spastic paraplegia	0.000	0.911	0.089
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.911	0.089
E24.3 Ectopic ACTH syndrome	0.000	0.911	0.089
E24.1 Nelson's syndrome	0.000	0.911	0.089
E04.2 Non-toxic multinodular goitre	0.000	0.912	0.088
G70.9 Myoneural disorder, unspecified	0.000	0.912	0.088
M06 Other rheumatoid arthritis	0.088	0.912	0.000
M11 Other crystal arthropathies	0.087	0.912	0.000
G83.8 Other specified paralytic syndromes	0.000	0.913	0.086
N48.8 Other specified disorders of penis	0.087	0.913	0.000
E25.9 Adrenogenital disorder, unspecified	0.000	0.914	0.085
E25.8 Other adrenogenital disorders	0.000	0.914	0.085
E04.9 Non-toxic goitre, unspecified	0.000	0.915	0.085
G11.9 Hereditary ataxia, unspecified	0.000	0.915	0.085
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.915	0.085
M05.19 Rheumatoid lung disease (Site unspecified)	0.084	0.915	0.000
G11.8 Other hereditary ataxias	0.000	0.916	0.084
G11.3 Cerebellar ataxia with defective DNA repair	0.000	0.916	0.084
G11.2 Late-onset cerebellar ataxia	0.000	0.916	0.084
G11.0 Congenital nonprogressive ataxia	0.000	0.916	0.084
G61 Inflammatory polyneuropathy	0.000	0.916	0.084
M12.2 Villonodular synovitis (pigmented)	0.084	0.916	0.000
N48.1 Balanoposthitis	0.083	0.917	0.000
G64 Other disorders of peripheral nervous system	0.000	0.917	0.082
M35.1 Other overlap syndromes	0.000	0.918	0.082
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.918	0.082
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.918	0.082
E50-E64 Other nutritional deficiencies	0.000	0.918	0.082
M05.10 Rheumatoid lung disease (Multiple sites)	0.081	0.919	0.000
E24.0 Pituitary-dependent Cushing's disease	0.000	0.919	0.081
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.081	0.919	0.000
G62.9 Polyneuropathy, unspecified	0.000	0.919	0.081
M13 Other arthritis	0.081	0.919	0.000
M08.0 Juvenile rheumatoid arthritis	0.080	0.920	0.000
N48.6 Balanitis xerotica obliterans	0.079	0.921	0.000
N42.8 Other specified disorders of prostate	0.079	0.921	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.921	0.078
E23.1 Drug-induced hypopituitarism	0.000	0.921	0.078
G04.1 Tropical spastic paraplegia	0.000	0.922	0.078
E34.8 Other specified endocrine disorders	0.000	0.922	0.078
M05.18 Rheumatoid lung disease (Other)	0.078	0.922	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.078	0.922	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.078	0.922	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.078	0.922	0.000
M05.14 Rheumatoid lung disease (Hand)	0.078	0.922	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.078	0.922	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.078	0.922	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.078	0.922	0.000
E23.6 Other disorders of pituitary gland	0.000	0.922	0.078
M08.9 Juvenile arthritis, unspecified	0.077	0.922	0.000
M08.8 Other juvenile arthritis	0.077	0.922	0.000
M08.4 Pauciarticular juvenile arthritis	0.077	0.922	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.077	0.922	0.000
M08.2 Juvenile arthritis with systemic onset	0.077	0.922	0.000
M08.1 Juvenile ankylosing spondylitis	0.077	0.922	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.077	0.922	0.000
M12.4 Intermittent hydrarthrosis	0.077	0.922	0.000
M12.1 Kaschin-Beck disease	0.077	0.922	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.077	0.922	0.000
N48.9 Disorder of penis, unspecified	0.077	0.923	0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.000	0.923	0.077
M06.3 Rheumatoid nodule	0.076	0.924	0.000
M12.3 Palindromic rheumatism	0.076	0.924	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.075	0.924	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.075	0.924	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.075	0.924	0.000
M09.0 Juvenile arthritis in psoriasis	0.075	0.924	0.000
G71.0 Muscular dystrophy	0.000	0.925	0.075
G11.1 Early-onset cerebellar ataxia	0.000	0.926	0.074
N42 Other disorders of prostate	0.074	0.926	0.000
M12.5 Traumatic arthropathy	0.074	0.926	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.926	0.073
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.000	0.927	0.073
D69.9 Haemorrhagic condition, unspecified	0.000	0.927	0.073
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.927	0.073
E45 Retarded development following protein-energy malnutrition	0.000	0.927	0.073
E43 Unspecified severe protein-energy malnutrition	0.000	0.927	0.073
E42 Marasmic kwashiorkor	0.000	0.927	0.073
E41 Nutritional marasmus	0.000	0.927	0.073
E40 Kwashiorkor	0.000	0.927	0.073
G80.9 Infantile cerebral palsy, unspecified	0.000	0.927	0.073
E29.8 Other testicular dysfunction	0.000	0.928	0.072
E29.0 Testicular hyperfunction	0.000	0.928	0.072
M05.09 Felty's syndrome (Site unspecified)	0.072	0.928	0.000
M05.08 Felty's syndrome (Other)	0.072	0.928	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.072	0.928	0.000
M05.06 Felty's syndrome (Lower leg)	0.072	0.928	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.072	0.928	0.000
M05.04 Felty's syndrome (Hand)	0.072	0.928	0.000
M05.03 Felty's syndrome (Forearm)	0.072	0.928	0.000
M05.02 Felty's syndrome (Upper arm)	0.072	0.928	0.000
M05.01 Felty's syndrome (Shoulder region)	0.072	0.928	0.000
M05.00 Felty's syndrome (Multiple sites)	0.072	0.928	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.072	0.928	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.072	0.928	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations