TreeWAS – Variant ID: rs28752928

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
R31 Unspecified haematuria	1.000	0.000	0.000
E03 Other hypothyroidism	0.000	0.002	0.998
L40.0 Psoriasis vulgaris	0.996	0.004	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.006	0.994
E00-E07 Disorders of thyroid gland	0.000	0.007	0.993
E05.9 Thyrotoxicosis, unspecified	0.000	0.007	0.993
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.019	0.981
M45 Ankylosing spondylitis	0.968	0.032	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.959	0.041	0.000
M07.3 Other psoriatic arthropathies	0.907	0.093	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.094	0.906
L40.4 Guttate psoriasis	0.906	0.094	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.899	0.101	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.891	0.109	0.000
E07 Other disorders of thyroid	0.000	0.125	0.875
M07.36 Other psoriatic arthropathies (Lower leg)	0.855	0.145	0.000
G35 Multiple sclerosis	0.000	0.148	0.852
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.835	0.165	0.000
M35.0 Sicca syndrome [Sjogren]	0.000	0.176	0.824
K90 Intestinal malabsorption	0.000	0.197	0.803
E03.8 Other specified hypothyroidism	0.000	0.197	0.803
E07.8 Other specified disorders of thyroid	0.000	0.219	0.781
M45.X2 Ankylosing spondylitis (Cervical region)	0.780	0.220	0.000
L40.8 Other psoriasis	0.776	0.224	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.772	0.228	0.000
L40.1 Generalised pustular psoriasis	0.760	0.240	0.000
M07.38 Other psoriatic arthropathies (Other)	0.749	0.251	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.733	0.267	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.275	0.725
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.283	0.717
L40.2 Acrodermatitis continua	0.717	0.283	0.000
E03.5 Myxoedema coma	0.000	0.285	0.715
E03.4 Atrophy of thyroid (acquired)	0.000	0.285	0.715
E03.3 Postinfectious hypothyroidism	0.000	0.285	0.715
E05.5 Thyroid crisis or storm	0.000	0.287	0.713
E05.4 Thyrotoxicosis factitia	0.000	0.287	0.713
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.287	0.713
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.288	0.712
E00 Congenital iodine-deficiency syndrome	0.000	0.288	0.712
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.694	0.306	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.694	0.306	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.694	0.306	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.694	0.306	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.694	0.306	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.694	0.306	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.679	0.321	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.671	0.329	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.345	0.654
E03.1 Congenital hypothyroidism without goitre	0.000	0.349	0.651
E07.9 Disorder of thyroid, unspecified	0.000	0.349	0.651
M07.33 Other psoriatic arthropathies (Forearm)	0.651	0.349	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.651	0.349	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.355	0.645
L40.3 Pustulosis palmaris et plantaris	0.639	0.361	0.000
E07.1 Dyshormogenetic goitre	0.000	0.373	0.627
E07.0 Hypersecretion of calcitonin	0.000	0.373	0.627
K90.8 Other intestinal malabsorption	0.000	0.374	0.626
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.379	0.621
K90.3 Pancreatic steatorrhoea	0.000	0.424	0.576
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.424	0.576
K90.1 Tropical sprue	0.000	0.424	0.576
E05.8 Other thyrotoxicosis	0.000	0.431	0.568
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.489	0.511
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.489	0.511
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.489	0.511
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.489	0.511
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.489	0.511
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.489	0.511
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.489	0.511
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.489	0.511
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.517	0.483
L40-L45 Papulosquamous disorders	0.468	0.532	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.544	0.456
M07 Psoriatic and enteropathic arthropathies	0.422	0.577	0.000
E06 Thyroiditis	0.000	0.599	0.401
L41 Parapsoriasis	0.366	0.634	0.000
L42 Pityriasis rosea	0.355	0.645	0.000
L44 Other papulosquamous disorders	0.338	0.662	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.335	0.665	0.000
G36 Other acute disseminated demyelination	0.000	0.666	0.334
G30-G32 Other degenerative diseases of the nervous system	0.000	0.684	0.316
Chapter VI Diseases of the nervous system	0.000	0.686	0.314
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.687	0.313
E06.3 Autoimmune thyroiditis	0.000	0.693	0.306
M07.5 Arthropathy in ulcerative colitis	0.303	0.697	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.303	0.697	0.000
M07.2 Psoriatic spondylitis	0.303	0.697	0.000
M07.1 Arthritis mutilans	0.303	0.697	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.303	0.697	0.000
G31.2 Degeneration of nervous system due to alcohol	0.000	0.700	0.300
L43 Lichen planus	0.299	0.700	0.000
L41.1 Pityriasis lichenoides chronica	0.293	0.707	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.711	0.289
G70-G73 Diseases of myoneural junction and muscle	0.000	0.711	0.289
E06.4 Drug-induced thyroiditis	0.000	0.712	0.287
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.712	0.287
E06.0 Acute thyroiditis	0.000	0.712	0.287
G00-G09 Inflammatory diseases of the central nervous system	0.000	0.714	0.286
G72 Other myopathies	0.000	0.718	0.282
M07.6 Other enteropathic arthropathies	0.280	0.720	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.721	0.279
G80-G83 Cerebral palsy and other paralytic syndromes	0.000	0.728	0.272
G72.9 Myopathy, unspecified	0.000	0.733	0.267
G30 Alzheimer's disease	0.000	0.736	0.264
G09 Sequelae of inflammatory diseases of central nervous system	0.000	0.736	0.264
L41.9 Parapsoriasis, unspecified	0.262	0.738	0.000
L41.8 Other parapsoriasis	0.262	0.738	0.000
L41.5 Retiform parapsoriasis	0.262	0.738	0.000
L41.4 Large plaque parapsoriasis	0.262	0.738	0.000
L41.3 Small plaque parapsoriasis	0.262	0.738	0.000
L41.2 Lymphomatoid papulosis	0.262	0.738	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.262	0.738	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.738	0.262
G31.8 Other specified degenerative diseases of nervous system	0.000	0.753	0.247
G36.0 Neuromyelitis optica [Devic]	0.000	0.753	0.247
L44.0 Pityriasis rubra pilaris	0.245	0.755	0.000
L44.9 Papulosquamous disorder, unspecified	0.242	0.758	0.000
L44.8 Other specified papulosquamous disorders	0.242	0.758	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.242	0.758	0.000
L44.3 Lichen ruber moniliformis	0.242	0.758	0.000
L44.2 Lichen striatus	0.242	0.758	0.000
L44.1 Lichen nitidus	0.242	0.758	0.000
G36.9 Acute disseminated demyelination, unspecified	0.000	0.760	0.240
G36.8 Other specified acute disseminated demyelination	0.000	0.760	0.240
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.760	0.240
G00 Bacterial meningitis, not elsewhere classified	0.000	0.761	0.239
G72.8 Other specified myopathies	0.000	0.762	0.238
G82 Paraplegia and tetraplegia	0.000	0.763	0.236
E27 Other disorders of adrenal gland	0.000	0.765	0.235
E06.5 Other chronic thyroiditis	0.001	0.766	0.234
G31.0 Circumscribed brain atrophy	0.000	0.769	0.231
G06 Intracranial and intraspinal abscess and granuloma	0.000	0.773	0.227
G82.1 Spastic paraplegia	0.000	0.775	0.225
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.775	0.225
D69.6 Thrombocytopenia, unspecified	0.000	0.775	0.225
G72.1 Alcoholic myopathy	0.000	0.776	0.224
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.777	0.223
G83 Other paralytic syndromes	0.000	0.778	0.221
L43.8 Other lichen planus	0.220	0.780	0.000
G72.0 Drug-induced myopathy	0.000	0.782	0.218
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.217	0.782	0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.217	0.782	0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.217	0.782	0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.217	0.782	0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.217	0.782	0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.217	0.782	0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.217	0.782	0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.217	0.782	0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.217	0.782	0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.217	0.782	0.000
M07.19 Arthritis mutilans (Site unspecified)	0.217	0.782	0.000
M07.18 Arthritis mutilans (Other)	0.217	0.782	0.000
M07.17 Arthritis mutilans (Ankle and foot)	0.217	0.782	0.000
M07.16 Arthritis mutilans (Lower leg)	0.217	0.782	0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.217	0.782	0.000
M07.14 Arthritis mutilans (Hand)	0.217	0.782	0.000
M07.13 Arthritis mutilans (Forearm)	0.217	0.782	0.000
M07.12 Arthritis mutilans (Upper arm)	0.217	0.782	0.000
M07.11 Arthritis mutilans (Shoulder region)	0.217	0.782	0.000
M07.10 Arthritis mutilans (Multiple sites)	0.217	0.782	0.000
M07.29 Psoriatic spondylitis (Site unspecified)	0.217	0.782	0.000
M07.28 Psoriatic spondylitis (Other)	0.217	0.782	0.000
M07.27 Psoriatic spondylitis (Ankle and foot)	0.217	0.782	0.000
M07.26 Psoriatic spondylitis (Lower leg)	0.217	0.782	0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.217	0.782	0.000
M07.24 Psoriatic spondylitis (Hand)	0.217	0.782	0.000
M07.23 Psoriatic spondylitis (Forearm)	0.217	0.782	0.000
M07.22 Psoriatic spondylitis (Upper arm)	0.217	0.782	0.000
M07.21 Psoriatic spondylitis (Shoulder region)	0.217	0.782	0.000
M07.20 Psoriatic spondylitis (Multiple sites)	0.217	0.782	0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.217	0.782	0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.217	0.782	0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.217	0.782	0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.217	0.782	0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.217	0.782	0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.217	0.782	0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.217	0.782	0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.217	0.782	0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.217	0.782	0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.217	0.782	0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.217	0.782	0.000
M07.58 Arthropathy in ulcerative colitis (Other)	0.217	0.782	0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.217	0.782	0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.217	0.782	0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.217	0.782	0.000
M07.54 Arthropathy in ulcerative colitis (Hand)	0.217	0.782	0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.217	0.782	0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.217	0.782	0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.217	0.782	0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.217	0.782	0.000
E06.1 Subacute thyroiditis	0.001	0.785	0.215
L43.3 Subacute (active) lichen planus	0.215	0.785	0.000
L43.2 Lichenoid drug reaction	0.215	0.785	0.000
L43.1 Bullous lichen planus	0.215	0.785	0.000
G30.0 Alzheimer's disease with early onset	0.000	0.786	0.213
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.000	0.787	0.213
G83.4 Cauda equina syndrome	0.000	0.789	0.211
E04 Other non-toxic goitre	0.000	0.790	0.210
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.000	0.793	0.207
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.000	0.795	0.205
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.000	0.795	0.205
G03 Meningitis due to other and unspecified causes	0.000	0.795	0.204
L43.0 Hypertrophic lichen planus	0.204	0.796	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.796	0.204
G00.9 Bacterial meningitis, unspecified	0.000	0.797	0.203
G72.3 Periodic paralysis	0.000	0.798	0.202
G72.2 Myopathy due to other toxic agents	0.000	0.798	0.202
E27.2 Addisonian crisis	0.000	0.798	0.202
M07.68 Other enteropathic arthropathies (Other)	0.201	0.799	0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.201	0.799	0.000
M07.66 Other enteropathic arthropathies (Lower leg)	0.201	0.799	0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.201	0.799	0.000
M07.64 Other enteropathic arthropathies (Hand)	0.201	0.799	0.000
M07.63 Other enteropathic arthropathies (Forearm)	0.201	0.799	0.000
M07.62 Other enteropathic arthropathies (Upper arm)	0.201	0.799	0.000
M07.61 Other enteropathic arthropathies (Shoulder region)	0.201	0.799	0.000
M07.60 Other enteropathic arthropathies (Multiple sites)	0.201	0.799	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.000	0.799	0.200
G30.1 Alzheimer's disease with late onset	0.000	0.800	0.200
G30.8 Other Alzheimer's disease	0.000	0.803	0.197
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.000	0.804	0.196
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.000	0.807	0.193
G30.9 Alzheimer's disease, unspecified	0.000	0.807	0.193
G06.1 Intraspinal abscess and granuloma	0.000	0.808	0.192
G81 Hemiplegia	0.000	0.808	0.192
E06.9 Thyroiditis, unspecified	0.001	0.809	0.190
E20-E35 Disorders of other endocrine glands	0.000	0.811	0.189
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.000	0.812	0.188
G82.5 Tetraplegia, unspecified	0.000	0.812	0.188
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.813	0.187
L43.9 Lichen planus, unspecified	0.186	0.814	0.000
G72.4 Inflammatory myopathy, not elsewhere classified	0.000	0.816	0.184
G83.9 Paralytic syndrome, unspecified	0.000	0.816	0.184
G37 Other demyelinating diseases of central nervous system	0.000	0.817	0.183
M07.69 Other enteropathic arthropathies (Site unspecified)	0.178	0.822	0.000
G82.4 Spastic tetraplegia	0.000	0.823	0.177
G80 Infantile cerebral palsy	0.000	0.824	0.176
G71 Primary disorders of muscles	0.000	0.824	0.175
G00.1 Pneumococcal meningitis	0.000	0.825	0.175
G00.8 Other bacterial meningitis	0.000	0.829	0.171
G00.3 Staphylococcal meningitis	0.000	0.829	0.171
G00.2 Streptococcal meningitis	0.000	0.829	0.171
G00.0 Haemophilus meningitis	0.000	0.829	0.171
E28 Ovarian dysfunction	0.000	0.830	0.170
G82.3 Flaccid tetraplegia	0.000	0.830	0.170
E04.0 Non-toxic diffuse goitre	0.000	0.831	0.169
E27.5 Adrenomedullary hyperfunction	0.000	0.832	0.168
E27.0 Other adrenocortical overactivity	0.000	0.832	0.168
E20 Hypoparathyroidism	0.000	0.836	0.164
G06.0 Intracranial abscess and granuloma	0.000	0.836	0.164
G02.0 Meningitis in viral diseases classified elsewhere	0.000	0.839	0.161
G83.5 Locked-in syndrome	0.000	0.841	0.159
G83.0 Diplegia of upper limbs	0.000	0.841	0.159
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.000	0.842	0.158
E27.8 Other specified disorders of adrenal gland	0.000	0.842	0.158
G83.1 Monoplegia of lower limb	0.000	0.844	0.156
E28.3 Primary ovarian failure	0.000	0.844	0.156
G70 Myasthenia gravis and other myoneural disorders	0.000	0.844	0.155
G12 Spinal muscular atrophy and related syndromes	0.000	0.845	0.155
G82.0 Flaccid paraplegia	0.000	0.846	0.154
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.000	0.847	0.153
G02.1 Meningitis in mycoses	0.000	0.847	0.153
E04.8 Other specified non-toxic goitre	0.000	0.849	0.151
G73.7 Myopathy other diseases classified elsewhere	0.000	0.851	0.149
G73.6 Myopathy in metabolic diseases	0.000	0.851	0.149
G73.5 Myopathy in endocrine diseases	0.000	0.851	0.149
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere	0.000	0.851	0.149
G73.3 Myasthenic syndromes in other diseases classified elsewhere	0.000	0.851	0.149
G73.2 Other myasthenic syndromes in neoplastic disease	0.000	0.851	0.149
G73.1 Eaton-Lambert syndrome	0.000	0.851	0.149
G73.0 Myasthenic syndromes in endocrine diseases	0.000	0.851	0.149
G06.2 Extradural and subdural abscess, unspecified	0.000	0.851	0.149
G81.1 Spastic hemiplegia	0.000	0.852	0.148
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.000	0.853	0.147
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.000	0.853	0.147
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.000	0.853	0.147
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.000	0.853	0.147
G03.8 Meningitis due to other specified causes	0.000	0.853	0.147
G03.2 Benign recurrent meningitis [Mollaret]	0.000	0.853	0.147
G03.1 Chronic meningitis	0.000	0.853	0.147
G03.0 Nonpyogenic meningitis	0.000	0.853	0.147
E20.9 Hypoparathyroidism, unspecified	0.000	0.853	0.147
G03.9 Meningitis, unspecified	0.000	0.854	0.146
G83.3 Monoplegia, unspecified	0.000	0.860	0.140
G11 Hereditary ataxia	0.000	0.862	0.138
G81.0 Flaccid hemiplegia	0.000	0.862	0.137
G80.0 Spastic cerebral palsy	0.000	0.863	0.137
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.864	0.136
E32 Diseases of thymus	0.000	0.864	0.136
E31 Polyglandular dysfunction	0.000	0.864	0.136
E30 Disorders of puberty, not elsewhere classified	0.000	0.864	0.136
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.865	0.135
G71.3 Mitochondrial myopathy, not elsewhere classified	0.000	0.865	0.135
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.866	0.134
G10 Huntington's disease	0.000	0.867	0.133
G14 Postpolio syndrome	0.000	0.868	0.131
G37.5 Concentric sclerosis [Balo]	0.000	0.869	0.131
G37.4 Subacute necrotising myelitis	0.000	0.869	0.131
G37.2 Central pontine myelinolysis	0.000	0.869	0.131
G37.1 Central demyelination of corpus callosum	0.000	0.869	0.131
G37.0 Diffuse sclerosis	0.000	0.869	0.131
G80.8 Other infantile cerebral palsy	0.000	0.869	0.131
M05-M14 Inflammatory polyarthropathies	0.131	0.869	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.000	0.870	0.130
E24 Cushing's syndrome	0.000	0.871	0.129
G80.2 Infantile hemiplegia	0.000	0.873	0.127
G80.4 Ataxic cerebral palsy	0.000	0.873	0.126
G80.3 Dyskinetic cerebral palsy	0.000	0.873	0.126
G71.9 Primary disorder of muscle, unspecified	0.000	0.874	0.126
G71.8 Other primary disorders of muscles	0.000	0.874	0.126
G71.2 Congenital myopathies	0.000	0.874	0.126
G62 Other polyneuropathies	0.000	0.874	0.126
G12.2 Motor neuron disease	0.000	0.875	0.125
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.875	0.125
M05 Seropositive rheumatoid arthritis	0.124	0.876	0.000
E25 Adrenogenital disorders	0.000	0.876	0.123
E28.2 Polycystic ovarian syndrome	0.000	0.877	0.123
E28.9 Ovarian dysfunction, unspecified	0.000	0.878	0.122
E28.8 Other ovarian dysfunction	0.000	0.878	0.122
E28.1 Androgen excess	0.000	0.878	0.122
E28.0 Oestrogen excess	0.000	0.878	0.122
G80.1 Spastic diplegia	0.000	0.879	0.121
G81.9 Hemiplegia, unspecified	0.000	0.879	0.121
M05.9 Seropositive rheumatoid arthritis, unspecified	0.119	0.881	0.000
D69 Purpura and other haemorrhagic conditions	0.000	0.881	0.119
M35 Other systemic involvement of connective tissue	0.000	0.882	0.118
E20.8 Other hypoparathyroidism	0.000	0.882	0.118
E20.1 Pseudohypoparathyroidism	0.000	0.882	0.118
E20.0 Idiopathic hypoparathyroidism	0.000	0.882	0.118
G71.1 Myotonic disorders	0.000	0.883	0.117
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere	0.000	0.884	0.116
G61 Inflammatory polyneuropathy	0.000	0.884	0.116
E23 Hypofunction and other disorders of pituitary gland	0.000	0.885	0.115
G83.8 Other specified paralytic syndromes	0.000	0.887	0.113
G70.8 Other specified myoneural disorders	0.000	0.888	0.112
G70.2 Congenital and developmental myasthenia	0.000	0.888	0.112
G70.1 Toxic myoneural disorders	0.000	0.888	0.112
G12.9 Spinal muscular atrophy, unspecified	0.000	0.889	0.111
G12.8 Other spinal muscular atrophies and related syndromes	0.000	0.889	0.111
G12.1 Other inherited spinal muscular atrophy	0.000	0.889	0.111
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]	0.000	0.889	0.111
G62.9 Polyneuropathy, unspecified	0.000	0.890	0.110
G70.9 Myoneural disorder, unspecified	0.000	0.890	0.109
G64 Other disorders of peripheral nervous system	0.000	0.891	0.109
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.108	0.892	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.893	0.107
G11.4 Hereditary spastic paraplegia	0.000	0.895	0.105
E24.2 Drug-induced Cushing's syndrome	0.000	0.895	0.104
E29 Testicular dysfunction	0.000	0.896	0.104
E26 Hyperaldosteronism	0.000	0.897	0.103
E23.2 Diabetes insipidus	0.000	0.899	0.101
G11.9 Hereditary ataxia, unspecified	0.000	0.900	0.100
E34 Other endocrine disorders	0.000	0.900	0.100
E40-E46 Malnutrition	0.000	0.900	0.100
D69.4 Other primary thrombocytopenia	0.000	0.900	0.100
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.099	0.901	0.000
G11.8 Other hereditary ataxias	0.000	0.901	0.099
G11.3 Cerebellar ataxia with defective DNA repair	0.000	0.901	0.099
G11.2 Late-onset cerebellar ataxia	0.000	0.901	0.099
G11.0 Congenital nonprogressive ataxia	0.000	0.901	0.099
E16 Other disorders of pancreatic internal secretion	0.000	0.901	0.099
E30.9 Disorder of puberty, unspecified	0.000	0.902	0.097
E30.8 Other disorders of puberty	0.000	0.902	0.097
E30.1 Precocious puberty	0.000	0.902	0.097
E30.0 Delayed puberty	0.000	0.902	0.097
E31.9 Polyglandular dysfunction, unspecified	0.000	0.902	0.097
E31.8 Other polyglandular dysfunction	0.000	0.902	0.097
E31.1 Polyglandular hyperfunction	0.000	0.902	0.097
E31.0 Autoimmune polyglandular failure	0.000	0.902	0.097
E32.9 Disease of thymus, unspecified	0.000	0.902	0.097
E32.8 Other diseases of thymus	0.000	0.902	0.097
E32.1 Abscess of thymus	0.000	0.902	0.097
E32.0 Persistent hyperplasia of thymus	0.000	0.902	0.097
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.902	0.097
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.902	0.097
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.902	0.097
E15 Nondiabetic hypoglycaemic coma	0.000	0.903	0.097
E24.8 Other Cushing's syndrome	0.000	0.903	0.097
M05.1 Rheumatoid lung disease	0.097	0.903	0.000
M08 Juvenile arthritis	0.096	0.904	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.096	0.904	0.000
M12 Other specific arthropathies	0.096	0.904	0.000
G62.1 Alcoholic polyneuropathy	0.000	0.904	0.096
M09 Juvenile arthritis in diseases classified elsewhere	0.094	0.906	0.000
G04.1 Tropical spastic paraplegia	0.000	0.906	0.093
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.093	0.907	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.907	0.093
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.908	0.092
E24.3 Ectopic ACTH syndrome	0.000	0.908	0.092
E24.1 Nelson's syndrome	0.000	0.908	0.092
D69.5 Secondary thrombocytopenia	0.000	0.908	0.092
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.000	0.908	0.092
G71.0 Muscular dystrophy	0.000	0.908	0.091
G80.9 Infantile cerebral palsy, unspecified	0.000	0.908	0.091
G61.8 Other inflammatory polyneuropathies	0.000	0.909	0.091
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.091	0.909	0.000
G62.2 Polyneuropathy due to other toxic agents	0.000	0.910	0.090
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.910	0.090
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.090	0.910	0.000
D69.2 Other nonthrombocytopenic purpura	0.000	0.910	0.090
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.089	0.910	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.089	0.911	0.000
M05.0 Felty's syndrome	0.089	0.911	0.000
E25.9 Adrenogenital disorder, unspecified	0.000	0.911	0.089
E25.8 Other adrenogenital disorders	0.000	0.911	0.089
G62.8 Other specified polyneuropathies	0.000	0.911	0.089
M14 Arthropathies in other diseases classified elsewhere	0.088	0.912	0.000
D69.0 Allergic purpura	0.000	0.912	0.088
G11.1 Early-onset cerebellar ataxia	0.000	0.912	0.087
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.000	0.912	0.087
M05.8 Other seropositive rheumatoid arthritis	0.087	0.913	0.000
G61.0 Guillain-Barre syndrome	0.000	0.914	0.086
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.086	0.914	0.000
D69.8 Other specified haemorrhagic conditions	0.000	0.914	0.085
M35.8 Other specified systemic involvement of connective tissue	0.000	0.915	0.085
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.915	0.085
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.915	0.085
M35.5 Multifocal fibrosclerosis	0.000	0.915	0.085
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.915	0.085
E50-E64 Other nutritional deficiencies	0.000	0.915	0.085
E24.0 Pituitary-dependent Cushing's disease	0.000	0.915	0.085
M05.2 Rheumatoid vasculitis	0.084	0.916	0.000
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere	0.000	0.916	0.083
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema	0.000	0.916	0.083
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.916	0.083
G83.2 Monoplegia of upper limb	0.001	0.916	0.083
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.083	0.917	0.000
G61.1 Serum neuropathy	0.000	0.917	0.083
M35.7 Hypermobility syndrome	0.000	0.917	0.083
M35.2 Behcet's disease	0.000	0.917	0.082
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.918	0.082
E23.1 Drug-induced hypopituitarism	0.000	0.918	0.082
E23.6 Other disorders of pituitary gland	0.000	0.918	0.082
E34.8 Other specified endocrine disorders	0.000	0.918	0.081
D69.1 Qualitative platelet defects	0.000	0.918	0.081
G60 Hereditary and idiopathic neuropathy	0.000	0.921	0.079
G04.0 Acute disseminated encephalitis	0.000	0.921	0.078
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease	0.000	0.922	0.078
E04.2 Non-toxic multinodular goitre	0.000	0.922	0.078
M11 Other crystal arthropathies	0.078	0.922	0.000
C44.3 Skin of other and unspecified parts of face	0.000	0.923	0.077
N48.4 Impotence of organic origin	0.077	0.923	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.923	0.076
N48.2 Other inflammatory disorders of penis	0.076	0.924	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.075	0.925	0.000
N48 Other disorders of penis	0.075	0.925	0.000
M12.2 Villonodular synovitis (pigmented)	0.075	0.925	0.000
E29.8 Other testicular dysfunction	0.000	0.925	0.075
E29.0 Testicular hyperfunction	0.000	0.925	0.075
E26.8 Other hyperaldosteronism	0.000	0.926	0.074
E26.1 Secondary hyperaldosteronism	0.000	0.926	0.074
G63 Polyneuropathy in diseases classified elsewhere	0.000	0.926	0.074
M06 Other rheumatoid arthritis	0.074	0.926	0.000
R94.3 Abnormal results of cardiovascular function studies	0.000	0.927	0.073
M13 Other arthritis	0.073	0.927	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.072	0.927	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.073	0.927	0.000
E34.5 Androgen resistance syndrome	0.000	0.928	0.072
E34.4 Constitutional tall stature	0.000	0.928	0.072
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.928	0.072
E34.1 Other hypersecretion of intestinal hormones	0.000	0.928	0.072
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.928	0.072
E45 Retarded development following protein-energy malnutrition	0.000	0.928	0.072
E43 Unspecified severe protein-energy malnutrition	0.000	0.928	0.072
E42 Marasmic kwashiorkor	0.000	0.928	0.072
E41 Nutritional marasmus	0.000	0.928	0.072
E40 Kwashiorkor	0.000	0.928	0.072
M08.0 Juvenile rheumatoid arthritis	0.072	0.928	0.000
E16.2 Hypoglycaemia, unspecified	0.000	0.928	0.072
G61.9 Inflammatory polyneuropathy, unspecified	0.000	0.929	0.071
E26.9 Hyperaldosteronism, unspecified	0.000	0.929	0.071
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.929	0.071
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.929	0.071
E16.4 Abnormal secretion of gastrin	0.000	0.929	0.071
E16.3 Increased secretion of glucagon	0.000	0.929	0.071
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.929	0.071
M05.18 Rheumatoid lung disease (Other)	0.070	0.930	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.070	0.930	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.070	0.930	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.070	0.930	0.000
M05.14 Rheumatoid lung disease (Hand)	0.070	0.930	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.070	0.930	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.070	0.930	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.070	0.930	0.000
E29.9 Testicular dysfunction, unspecified	0.000	0.930	0.069
M08.9 Juvenile arthritis, unspecified	0.069	0.931	0.000
M08.8 Other juvenile arthritis	0.069	0.931	0.000
M08.4 Pauciarticular juvenile arthritis	0.069	0.931	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.069	0.931	0.000
M08.2 Juvenile arthritis with systemic onset	0.069	0.931	0.000
M08.1 Juvenile ankylosing spondylitis	0.069	0.931	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.069	0.931	0.000
M12.4 Intermittent hydrarthrosis	0.069	0.931	0.000
M12.1 Kaschin-Beck disease	0.069	0.931	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations