TreeWAS – Variant ID: rs2877832

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M81.99 Osteoporosis, unspecified (Site unspecified)	0.121	0.879	0.000
M81.9 Osteoporosis, unspecified	0.107	0.893	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.095	0.905	0.000
M81.98 Osteoporosis, unspecified (Other)	0.093	0.907	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.077	0.923	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.077	0.923	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.077	0.923	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.077	0.923	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.077	0.923	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.074	0.926	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.071	0.928	0.000
M81 Osteoporosis without pathological fracture	0.066	0.934	0.000
M81.4 Drug-induced osteoporosis	0.053	0.947	0.000
M81.8 Other osteoporosis	0.048	0.952	0.000
M81.6 Localised osteoporosis [Lequesne]	0.048	0.952	0.000
M81.5 Idiopathic osteoporosis	0.048	0.952	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.048	0.952	0.000
M81.1 Postoophorectomy osteoporosis	0.048	0.952	0.000
M81.0 Postmenopausal osteoporosis	0.048	0.952	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.046	0.954	0.000
M81.2 Osteoporosis of disuse	0.044	0.956	0.000
M81.48 Drug-induced osteoporosis (Other)	0.038	0.962	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.038	0.962	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.038	0.962	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.038	0.962	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.038	0.962	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.038	0.962	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.038	0.962	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.038	0.962	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.035	0.965	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.034	0.965	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.034	0.965	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.034	0.965	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.034	0.965	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.034	0.965	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.034	0.965	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.034	0.965	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.034	0.965	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.034	0.965	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.034	0.965	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.034	0.965	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.034	0.965	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.034	0.965	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.034	0.965	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.034	0.965	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.034	0.965	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.034	0.965	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.034	0.965	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.034	0.965	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.034	0.965	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.034	0.965	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.034	0.965	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.034	0.965	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.034	0.965	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.034	0.965	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.034	0.965	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.034	0.965	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.034	0.965	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.034	0.965	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.034	0.965	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.034	0.965	0.000
M81.58 Idiopathic osteoporosis (Other)	0.034	0.965	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.034	0.965	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.034	0.965	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.034	0.965	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.034	0.965	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.034	0.965	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.034	0.965	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.034	0.965	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.034	0.965	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.034	0.965	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.034	0.965	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.034	0.965	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.034	0.965	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.034	0.965	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.034	0.965	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.034	0.965	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.034	0.965	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.034	0.965	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.034	0.965	0.000
M81.89 Other osteoporosis (Site unspecified)	0.034	0.965	0.000
M81.88 Other osteoporosis (Other)	0.034	0.965	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.034	0.965	0.000
M81.86 Other osteoporosis (Lower leg)	0.034	0.965	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.034	0.965	0.000
M81.84 Other osteoporosis (Hand)	0.034	0.965	0.000
M81.83 Other osteoporosis (Forearm)	0.034	0.965	0.000
M81.82 Other osteoporosis (Upper arm)	0.034	0.965	0.000
M81.81 Other osteoporosis (Shoulder region)	0.034	0.965	0.000
M81.80 Other osteoporosis (Multiple sites)	0.034	0.965	0.000
M80-M85 Disorders of bone density and structure	0.033	0.967	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.031	0.968	0.000
M81.28 Osteoporosis of disuse (Other)	0.031	0.968	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.031	0.968	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.031	0.968	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.031	0.968	0.000
M81.24 Osteoporosis of disuse (Hand)	0.031	0.968	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.031	0.968	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.031	0.968	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.031	0.968	0.000
M84 Disorders of continuity of bone	0.029	0.971	0.000
M84.4 Pathological fracture, not elsewhere classified	0.027	0.972	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.027	0.972	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.027	0.973	0.000
M84.0 Malunion of fracture	0.026	0.974	0.000
M82 Osteoporosis in diseases classified elsewhere	0.024	0.975	0.000
M83 Adult osteomalacia	0.024	0.976	0.000
M85 Other disorders of bone density and structure	0.023	0.977	0.000
M84.03 Malunion of fracture (Forearm)	0.023	0.977	0.000
M84.04 Malunion of fracture (Hand)	0.022	0.978	0.000
M84.9 Disorder of continuity of bone, unspecified	0.021	0.979	0.000
M84.8 Other disorders of continuity of bone	0.021	0.979	0.000
M84.3 Stress fracture, not elsewhere classified	0.021	0.979	0.000
M84.2 Delayed union of fracture	0.021	0.979	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.020	0.980	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.020	0.980	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.020	0.980	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.020	0.980	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.020	0.980	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.020	0.980	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.020	0.980	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.020	0.980	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.019	0.980	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.019	0.981	0.000
M84.09 Malunion of fracture (Site unspecified)	0.019	0.981	0.000
M84.08 Malunion of fracture (Other)	0.019	0.981	0.000
M84.06 Malunion of fracture (Lower leg)	0.019	0.981	0.000
M84.01 Malunion of fracture (Shoulder region)	0.019	0.981	0.000
M84.00 Malunion of fracture (Multiple sites)	0.019	0.981	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.019	0.981	0.000
M84.02 Malunion of fracture (Upper arm)	0.018	0.981	0.000
M82.1 Osteoporosis in endocrine disorders	0.018	0.982	0.000
M85.2 Hyperostosis of skull	0.018	0.982	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.018	0.982	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.018	0.982	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.018	0.982	0.000
M85.9 Disorder of bone density and structure, unspecified	0.018	0.982	0.000
M83.9 Adult osteomalacia, unspecified	0.017	0.983	0.000
M83.8 Other adult osteomalacia	0.017	0.983	0.000
M83.5 Other drug-induced osteomalacia in adults	0.017	0.983	0.000
M83.4 Aluminum bone disease	0.017	0.983	0.000
M83.3 Adult osteomalacia due to malnutrition	0.017	0.983	0.000
M83.2 Adult osteomalacia due to malabsorption	0.017	0.983	0.000
M83.1 Senile osteomalacia	0.017	0.983	0.000
M83.0 Puerperal osteomalacia	0.017	0.983	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.017	0.983	0.000
M85.5 Aneurysmal bone cyst	0.017	0.983	0.000
M85.4 Solitary bone cyst	0.017	0.983	0.000
M85.3 Osteitis condensans	0.017	0.983	0.000
M85.1 Skeletal fluorosis	0.017	0.983	0.000
M85.6 Other cyst of bone	0.017	0.983	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.017	0.983	0.000
M85.0 Fibrous dysplasia (monostotic)	0.016	0.983	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.016	0.984	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.016	0.984	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.016	0.984	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.015	0.984	0.000
M84.28 Delayed union of fracture (Other)	0.015	0.984	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.015	0.984	0.000
M84.26 Delayed union of fracture (Lower leg)	0.015	0.984	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.015	0.984	0.000
M84.24 Delayed union of fracture (Hand)	0.015	0.984	0.000
M84.23 Delayed union of fracture (Forearm)	0.015	0.984	0.000
M84.22 Delayed union of fracture (Upper arm)	0.015	0.984	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.015	0.984	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.015	0.984	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.015	0.984	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.015	0.984	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.015	0.984	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.015	0.984	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.015	0.984	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.015	0.984	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.015	0.984	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.015	0.984	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.015	0.984	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.015	0.984	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.015	0.984	0.000
M84.88 Other disorders of continuity of bone (Other)	0.015	0.984	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.015	0.984	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.015	0.984	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.015	0.984	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.015	0.984	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.015	0.984	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.015	0.984	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.015	0.984	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.015	0.984	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.015	0.984	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.015	0.984	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.015	0.984	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.015	0.984	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.015	0.984	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.015	0.984	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.015	0.984	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.015	0.984	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.015	0.984	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.015	0.984	0.000
O75.0 Maternal distress during labour and delivery	0.015	0.985	0.000
M85.8 Other specified disorders of bone density and structure	0.015	0.985	0.000
M80 Osteoporosis with pathological fracture	0.014	0.986	0.000
M85.20 Hyperostosis of skull-Mult sites	0.014	0.986	0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.014	0.986	0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.013	0.986	0.000
M82.18 Osteoporosis in endocrine disorders (Other)	0.013	0.986	0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.013	0.986	0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.013	0.986	0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.013	0.986	0.000
M82.14 Osteoporosis in endocrine disorders (Hand)	0.013	0.986	0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.013	0.986	0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.013	0.986	0.000
M85.29 Hyperostosis of skull-Site unspec	0.013	0.987	0.000
M85.28 Hyperostosis of skull-Other	0.013	0.987	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.013	0.987	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.013	0.987	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.013	0.987	0.000
M85.24 Hyperostosis of skull-Hand	0.013	0.987	0.000
M85.23 Hyperostosis of skull-Forearm	0.013	0.987	0.000
M85.22 Hyperostosis of skull-Upper arm	0.013	0.987	0.000
M85.21 Hyperostosis of skull-Shldr region	0.013	0.987	0.000
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)	0.013	0.987	0.000
M82.08 Osteoporosis in multiple myelomatosis (Other)	0.013	0.987	0.000
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)	0.013	0.987	0.000
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)	0.013	0.987	0.000
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)	0.013	0.987	0.000
M82.04 Osteoporosis in multiple myelomatosis (Hand)	0.013	0.987	0.000
M82.03 Osteoporosis in multiple myelomatosis (Forearm)	0.013	0.987	0.000
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)	0.013	0.987	0.000
M82.01 Osteoporosis in multiple myelomatosis (Shoulder region)	0.013	0.987	0.000
M82.00 Osteoporosis in multiple myelomatosis (Multiple sites)	0.013	0.987	0.000
M82.89 Osteoporosis in other diseases classified elsewhere (Site unspecified)	0.013	0.987	0.000
M82.88 Osteoporosis in other diseases classified elsewhere (Other)	0.013	0.987	0.000
M82.87 Osteoporosis in other diseases classified elsewhere (Ankle and foot)	0.013	0.987	0.000
M82.86 Osteoporosis in other diseases classified elsewhere (Lower leg)	0.013	0.987	0.000
M82.85 Osteoporosis in other diseases classified elsewhere (Pelvic region and thigh)	0.013	0.987	0.000
M82.84 Osteoporosis in other diseases classified elsewhere (Hand)	0.013	0.987	0.000
M82.83 Osteoporosis in other diseases classified elsewhere (Forearm)	0.013	0.987	0.000
M82.82 Osteoporosis in other diseases classified elsewhere (Upper arm)	0.013	0.987	0.000
M82.81 Osteoporosis in other diseases classified elsewhere (Shoulder region)	0.013	0.987	0.000
M82.80 Osteoporosis in other diseases classified elsewhere (Multiple sites)	0.013	0.987	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.013	0.987	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.013	0.987	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.013	0.987	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.013	0.987	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.013	0.987	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.013	0.987	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.013	0.987	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.013	0.987	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.013	0.987	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.013	0.987	0.000
M83.09 Puerperal osteomalacia (Site unspecified)	0.012	0.987	0.000
M83.08 Puerperal osteomalacia (Other)	0.012	0.987	0.000
M83.07 Puerperal osteomalacia (Ankle and foot)	0.012	0.987	0.000
M83.06 Puerperal osteomalacia (Lower leg)	0.012	0.987	0.000
M83.05 Puerperal osteomalacia (Pelvic region and thigh)	0.012	0.987	0.000
M83.04 Puerperal osteomalacia (Hand)	0.012	0.987	0.000
M83.03 Puerperal osteomalacia (Forearm)	0.012	0.987	0.000
M83.02 Puerperal osteomalacia (Upper arm)	0.012	0.987	0.000
M83.01 Puerperal osteomalacia (Shoulder region)	0.012	0.987	0.000
M83.00 Puerperal osteomalacia (Multiple sites)	0.012	0.987	0.000
M83.19 Senile osteomalacia (Site unspecified)	0.012	0.987	0.000
M83.18 Senile osteomalacia (Other)	0.012	0.987	0.000
M83.17 Senile osteomalacia (Ankle and foot)	0.012	0.987	0.000
M83.16 Senile osteomalacia (Lower leg)	0.012	0.987	0.000
M83.15 Senile osteomalacia (Pelvic region and thigh)	0.012	0.987	0.000
M83.14 Senile osteomalacia (Hand)	0.012	0.987	0.000
M83.13 Senile osteomalacia (Forearm)	0.012	0.987	0.000
M83.12 Senile osteomalacia (Upper arm)	0.012	0.987	0.000
M83.11 Senile osteomalacia (Shoulder region)	0.012	0.987	0.000
M83.10 Senile osteomalacia (Multiple sites)	0.012	0.987	0.000
M83.29 Adult osteomalacia due to malabsorption (Site unspecified)	0.012	0.987	0.000
M83.28 Adult osteomalacia due to malabsorption (Other)	0.012	0.987	0.000
M83.27 Adult osteomalacia due to malabsorption (Ankle and foot)	0.012	0.987	0.000
M83.26 Adult osteomalacia due to malabsorption (Lower leg)	0.012	0.987	0.000
M83.25 Adult osteomalacia due to malabsorption (Pelvic region and thigh)	0.012	0.987	0.000
M83.24 Adult osteomalacia due to malabsorption (Hand)	0.012	0.987	0.000
M83.23 Adult osteomalacia due to malabsorption (Forearm)	0.012	0.987	0.000
M83.22 Adult osteomalacia due to malabsorption (Upper arm)	0.012	0.987	0.000
M83.21 Adult osteomalacia due to malabsorption (Shoulder region)	0.012	0.987	0.000
M83.20 Adult osteomalacia due to malabsorption (Multiple sites)	0.012	0.987	0.000
M83.39 Adult osteomalacia due to malnutrition (Site unspecified)	0.012	0.987	0.000
M83.38 Adult osteomalacia due to malnutrition (Other)	0.012	0.987	0.000
M83.37 Adult osteomalacia due to malnutrition (Ankle and foot)	0.012	0.987	0.000
M83.36 Adult osteomalacia due to malnutrition (Lower leg)	0.012	0.987	0.000
M83.35 Adult osteomalacia due to malnutrition (Pelvic region and thigh)	0.012	0.987	0.000
M83.34 Adult osteomalacia due to malnutrition (Hand)	0.012	0.987	0.000
M83.33 Adult osteomalacia due to malnutrition (Forearm)	0.012	0.987	0.000
M83.32 Adult osteomalacia due to malnutrition (Upper arm)	0.012	0.987	0.000
M83.31 Adult osteomalacia due to malnutrition (Shoulder region)	0.012	0.987	0.000
M83.30 Adult osteomalacia due to malnutrition (Multiple sites)	0.012	0.987	0.000
M83.49 Aluminium bone disease (Site unspecified)	0.012	0.987	0.000
M83.48 Aluminium bone disease (Other)	0.012	0.987	0.000
M83.47 Aluminium bone disease (Ankle and foot)	0.012	0.987	0.000
M83.46 Aluminium bone disease (Lower leg)	0.012	0.987	0.000
M83.45 Aluminium bone disease (Pelvic region and thigh)	0.012	0.987	0.000
M83.44 Aluminium bone disease (Hand)	0.012	0.987	0.000
M83.43 Aluminium bone disease (Forearm)	0.012	0.987	0.000
M83.42 Aluminium bone disease (Upper arm)	0.012	0.987	0.000
M83.41 Aluminium bone disease (Shoulder region)	0.012	0.987	0.000
M83.40 Aluminium bone disease (Multiple sites)	0.012	0.987	0.000
M83.59 Other drug-induced osteomalacia in adults (Site unspecified)	0.012	0.987	0.000
M83.58 Other drug-induced osteomalacia in adults (Other)	0.012	0.987	0.000
M83.57 Other drug-induced osteomalacia in adults (Ankle and foot)	0.012	0.987	0.000
M83.56 Other drug-induced osteomalacia in adults (Lower leg)	0.012	0.987	0.000
M83.55 Other drug-induced osteomalacia in adults (Pelvic region and thigh)	0.012	0.987	0.000
M83.54 Other drug-induced osteomalacia in adults (Hand)	0.012	0.987	0.000
M83.53 Other drug-induced osteomalacia in adults (Forearm)	0.012	0.987	0.000
M83.52 Other drug-induced osteomalacia in adults (Upper arm)	0.012	0.987	0.000
M83.51 Other drug-induced osteomalacia in adults (Shoulder region)	0.012	0.987	0.000
M83.50 Other drug-induced osteomalacia in adults (Multiple sites)	0.012	0.987	0.000
M83.89 Other adult osteomalacia (Site unspecified)	0.012	0.987	0.000
M83.88 Other adult osteomalacia (Other)	0.012	0.987	0.000
M83.87 Other adult osteomalacia (Ankle and foot)	0.012	0.987	0.000
M83.86 Other adult osteomalacia (Lower leg)	0.012	0.987	0.000
M83.85 Other adult osteomalacia (Pelvic region and thigh)	0.012	0.987	0.000
M83.84 Other adult osteomalacia (Hand)	0.012	0.987	0.000
M83.83 Other adult osteomalacia (Forearm)	0.012	0.987	0.000
M83.82 Other adult osteomalacia (Upper arm)	0.012	0.987	0.000
M83.81 Other adult osteomalacia (Shoulder region)	0.012	0.987	0.000
M83.80 Other adult osteomalacia (Multiple sites)	0.012	0.987	0.000
M83.99 Adult osteomalacia, unspecified (Site unspecified)	0.012	0.987	0.000
M83.98 Adult osteomalacia, unspecified (Other)	0.012	0.987	0.000
M83.97 Adult osteomalacia, unspecified (Ankle and foot)	0.012	0.987	0.000
M83.96 Adult osteomalacia, unspecified (Lower leg)	0.012	0.987	0.000
M83.95 Adult osteomalacia, unspecified (Pelvic region and thigh)	0.012	0.987	0.000
M83.94 Adult osteomalacia, unspecified (Hand)	0.012	0.987	0.000
M83.93 Adult osteomalacia, unspecified (Forearm)	0.012	0.987	0.000
M83.92 Adult osteomalacia, unspecified (Upper arm)	0.012	0.987	0.000
M83.91 Adult osteomalacia, unspecified (Shoulder region)	0.012	0.987	0.000
M83.90 Adult osteomalacia, unspecified (Multiple sites)	0.012	0.987	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.013	0.987	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.013	0.987	0.000
M85.19 Skeletal fluorosis (Site unspecified)	0.012	0.987	0.000
M85.18 Skeletal fluorosis (Other)	0.012	0.987	0.000
M85.17 Skeletal fluorosis (Ankle and foot)	0.012	0.987	0.000
M85.16 Skeletal fluorosis (Lower leg)	0.012	0.987	0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.012	0.987	0.000
M85.14 Skeletal fluorosis (Hand)	0.012	0.987	0.000
M85.13 Skeletal fluorosis (Forearm)	0.012	0.987	0.000
M85.12 Skeletal fluorosis (Upper arm)	0.012	0.987	0.000
M85.11 Skeletal fluorosis (Shoulder region)	0.012	0.987	0.000
M85.10 Skeletal fluorosis (Multiple sites)	0.012	0.987	0.000
M85.39 Osteitis condensans (Site unspecified)	0.012	0.987	0.000
M85.38 Osteitis condensans (Other)	0.012	0.987	0.000
M85.37 Osteitis condensans (Ankle and foot)	0.012	0.987	0.000
M85.36 Osteitis condensans (Lower leg)	0.012	0.987	0.000
M85.35 Osteitis condensans (Pelvic region and thigh)	0.012	0.987	0.000
M85.34 Osteitis condensans (Hand)	0.012	0.987	0.000
M85.33 Osteitis condensans (Forearm)	0.012	0.987	0.000
M85.32 Osteitis condensans (Upper arm)	0.012	0.987	0.000
M85.31 Osteitis condensans (Shoulder region)	0.012	0.987	0.000
M85.30 Osteitis condensans (Multiple sites)	0.012	0.987	0.000
M85.49 Solitary bone cyst (Site unspecified)	0.012	0.987	0.000
M85.48 Solitary bone cyst (Other)	0.012	0.987	0.000
M85.47 Solitary bone cyst (Ankle and foot)	0.012	0.987	0.000
M85.46 Solitary bone cyst (Lower leg)	0.012	0.987	0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.012	0.987	0.000
M85.44 Solitary bone cyst (Hand)	0.012	0.987	0.000
M85.43 Solitary bone cyst (Forearm)	0.012	0.987	0.000
M85.42 Solitary bone cyst (Upper arm)	0.012	0.987	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.012	0.987	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.012	0.987	0.000
M85.59 Aneurysmal bone cyst (Site unspecified)	0.012	0.987	0.000
M85.58 Aneurysmal bone cyst (Other)	0.012	0.987	0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.012	0.987	0.000
M85.56 Aneurysmal bone cyst (Lower leg)	0.012	0.987	0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.012	0.987	0.000
M85.54 Aneurysmal bone cyst (Hand)	0.012	0.987	0.000
M85.53 Aneurysmal bone cyst (Forearm)	0.012	0.987	0.000
M85.52 Aneurysmal bone cyst (Upper arm)	0.012	0.987	0.000
M85.51 Aneurysmal bone cyst (Shoulder region)	0.012	0.987	0.000
M85.50 Aneurysmal bone cyst (Multiple sites)	0.012	0.987	0.000
M85.69 Other cyst of bone (Site unspecified)	0.012	0.988	0.000
M85.68 Other cyst of bone (Other)	0.012	0.988	0.000
M85.66 Other cyst of bone (Lower leg)	0.012	0.988	0.000
M85.64 Other cyst of bone (Hand)	0.012	0.988	0.000
M85.63 Other cyst of bone (Forearm)	0.012	0.988	0.000
M85.62 Other cyst of bone (Upper arm)	0.012	0.988	0.000
M85.61 Other cyst of bone (Shoulder region)	0.012	0.988	0.000
M85.60 Other cyst of bone (Multiple sites)	0.012	0.988	0.000
O75.9 Complication of labour and delivery, unspecified	0.012	0.988	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.012	0.988	0.000
O75.4 Other complications of obstetric surgery and procedures	0.012	0.988	0.000
O75.3 Other infection during labour	0.012	0.988	0.000
O75.1 Shock during or following labour and delivery	0.012	0.988	0.000
Y40.0 Penicillins	0.012	0.988	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.012	0.988	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.012	0.988	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.012	0.988	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.012	0.988	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.012	0.988	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.012	0.988	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.012	0.988	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.012	0.988	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.012	0.988	0.000
N89.8 Other specified noninflammatory disorders of vagina	0.012	0.988	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.012	0.988	0.000
Y40 Systemic antibiotics	0.012	0.988	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.011	0.988	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.012	0.988	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.011	0.988	0.000
Y46.6 Other and unspecified antiepileptics	0.011	0.989	0.000
Y57 Other and unspecified drugs and medicaments	0.011	0.989	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.011	0.989	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.011	0.989	0.000
Y44 Agents primarily affecting blood constituents	0.011	0.989	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.011	0.989	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.011	0.989	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.011	0.989	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.011	0.989	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.011	0.989	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.011	0.989	0.000
O75.8 Other specified complications of labour and delivery	0.011	0.989	0.000
Y46.4 Iminostilbenes	0.011	0.989	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.011	0.989	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.010	0.989	0.000
M80.8 Other osteoporosis with pathological fracture	0.010	0.989	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.010	0.989	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.010	0.989	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.010	0.989	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.010	0.990	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.010	0.990	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.010	0.990	0.000
Y57.9 Drug or medicament, unspecified	0.010	0.990	0.000
V10-V19 Pedal cyclist injured in transport accident	0.010	0.990	0.000
Y46.7 Anti-Parkinsonism drugs	0.010	0.990	0.000
Y40.8 Other systemic antibiotics	0.010	0.990	0.000
Chapter XX External causes of morbidity and mortality	0.010	0.990	0.000
Y42.5 Other oestrogens and progestogens	0.010	0.990	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.010	0.990	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.009	0.990	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.009	0.990	0.000
Y57.8 Other drugs and medicaments	0.009	0.990	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.009	0.990	0.000
Y59 Other and unspecified vaccines and biological substances	0.009	0.991	0.000
Y58 Bacterial vaccines	0.009	0.991	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.009	0.991	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.009	0.991	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.009	0.991	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.009	0.991	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.009	0.991	0.000
Y46.8 Antispasticity drugs	0.009	0.991	0.000
Y46.5 Valproic acid	0.009	0.991	0.000
Y46.3 Deoxybarbiturates	0.009	0.991	0.000
Y46.1 Oxazolidinediones	0.009	0.991	0.000
Y46.0 Succinimides	0.009	0.991	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.009	0.991	0.000
Y46.2 Hydantoin derivatives	0.009	0.991	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.009	0.991	0.000
V19 Pedal cyclist injured in other and unspecified transport accidents	0.009	0.991	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.009	0.991	0.000
Y48 Anaesthetics and therapeutic gases	0.009	0.991	0.000
Y45.1 Salicylates	0.009	0.991	0.000
Y45.0 Opioids and related analgesics	0.009	0.991	0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.009	0.991	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.009	0.991	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.009	0.991	0.000
Y42.9 Other and unspecified hormone antagonists	0.009	0.991	0.000
Y42.4 Oral contraceptives	0.009	0.991	0.000
Y42.2 Antithyroid drugs	0.009	0.991	0.000
Y42.1 Thyroid hormones and substitutes	0.009	0.991	0.000
Y40.7 Antifungal antibiotics, systemically used	0.009	0.991	0.000
Y40.6 Rifamycins	0.009	0.991	0.000
Y40.5 Aminoglycosides	0.009	0.991	0.000
Y40.4 Tetracyclines	0.009	0.991	0.000
Y40.2 Chloramphenicol group	0.009	0.991	0.000
Y45.5 4-Aminophenol derivatives	0.009	0.991	0.000
Z45.0 Adjustment and management of cardiac pacemaker	0.009	0.991	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.009	0.991	0.000
V01-V09 Pedestrian injured in transport accident	0.009	0.991	0.000
Y44.2 Anticoagulants	0.009	0.991	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.009	0.991	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.009	0.991	0.000
V19.3 Pedal cyclist [any] injured in an unspecified nontraffic accident	0.009	0.991	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.008	0.991	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.008	0.991	0.000
W75-W84 Other accidental threats to breathing	0.008	0.991	0.000
Y44.5 Thrombolytic drugs	0.008	0.991	0.000
X50-X57 Overexertion, travel and privation	0.008	0.992	0.000
Y57.7 Vitamins, not elsewhere classified	0.008	0.992	0.000
Y57.6 Other diagnostic agents	0.008	0.992	0.000
Y57.4 Pharmaceutical excipients	0.008	0.992	0.000
Y57.3 Alcohol deterrents	0.008	0.992	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.008	0.992	0.000
Y57.1 Lipotropic drugs	0.008	0.992	0.000
Y57.0 Appetite depressants [anorectics]	0.008	0.992	0.000
Y49.2 Other and unspecified antidepressants	0.008	0.992	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.008	0.992	0.000
Y45.4 Antirheumatics	0.008	0.992	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.008	0.992	0.000
Y42.7 Androgens and anabolic congeners	0.008	0.992	0.000
Y45.8 Other analgesics and antipyretics	0.008	0.992	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.008	0.992	0.000
Y44.7 Plasma substitutes	0.008	0.992	0.000
Y44.6 Natural blood and blood products	0.008	0.992	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.008	0.992	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.008	0.992	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.008	0.992	0.000
Y00-Y09 Assault	0.008	0.992	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.007	0.992	0.001
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.008	0.992	0.000
W50-W64 Exposure to animate mechanical forces	0.008	0.992	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations