TreeWAS – Variant ID: rs2898261

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.000	0.091	0.909
I10-I15 Hypertensive diseases	0.000	0.598	0.402
I15 Secondary hypertension	0.000	0.651	0.349
I15.9 Seconday hypertension, unspecified	0.000	0.690	0.310
I12 Hypertensive renal disease	0.000	0.733	0.267
I13 Hypertensive heart and renal disease	0.000	0.735	0.265
I15.0 Renovascular hypertension	0.000	0.740	0.260
I11 Hypertensive heart disease	0.000	0.748	0.251
I15.2 Hypertension secondary to endocrine disorders	0.000	0.750	0.250
I15.1 Hypertension secondary to other renal disorders	0.000	0.752	0.247
I15.8 Other secondary hypertension	0.000	0.757	0.243
I12.9 Hypertensive renal disease without renal failure	0.000	0.765	0.235
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.810	0.190
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.810	0.190
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.810	0.190
R40.0 Somnolence	0.000	0.811	0.189
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.830	0.170
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.833	0.167
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.843	0.157
R40 Somnolence, stupor and coma	0.000	0.938	0.062
F17.1 Harmful use	0.000	0.944	0.056
S02.20 Fracture of nasal bones (closed)	0.043	0.957	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.957	0.043
R40.1 Stupor	0.000	0.958	0.042
R40.2 Coma, unspecified	0.000	0.966	0.034
E66.8 Other obesity	0.000	0.977	0.023
S02.2 Fracture of nasal bones	0.018	0.982	0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.000	0.983	0.017
M13.97 Arthritis, unspecified (Ankle and foot)	0.000	0.984	0.016
N20.1 Calculus of ureter	0.014	0.986	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.986	0.014
S02.21 Fracture of nasal bones (open)	0.012	0.988	0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.000	0.989	0.011
E04.2 Non-toxic multinodular goitre	0.000	0.989	0.011
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.000	0.989	0.011
M22.4 Chondromalacia patellae	0.010	0.990	0.000
E04 Other non-toxic goitre	0.000	0.990	0.010
R46 Symptoms and signs involving appearance and behaviour	0.000	0.991	0.009
L02 Cutaneous abscess, furuncle and carbuncle	0.000	0.991	0.009
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.000	0.991	0.009
M81.90 Osteoporosis, unspecified (Multiple sites)	0.009	0.991	0.000
E04.0 Non-toxic diffuse goitre	0.000	0.991	0.009
R43 Disturbances of smell and taste	0.000	0.991	0.009
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.000	0.991	0.009
M81.98 Osteoporosis, unspecified (Other)	0.009	0.991	0.000
R46.8 Other symptoms and signs involving appearance and behaviour	0.000	0.992	0.008
M81.9 Osteoporosis, unspecified	0.008	0.992	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.000	0.992	0.008
Z75.1 Person awaiting admission to adequate facility elsewhere	0.000	0.992	0.008
F17 Mental and behavioural disorders due to use of tobacco	0.000	0.992	0.008
E04.8 Other specified non-toxic goitre	0.000	0.992	0.008
R46.0 Very low level of personal hygiene	0.000	0.992	0.008
M31.6 Other giant cell arteritis	0.007	0.993	0.000
R43.8 Other and unspecified disturbances of smell and taste	0.000	0.993	0.007
R43.0 Anosmia	0.000	0.993	0.007
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.000	0.993	0.007
R46.2 Strange and inexplicable behaviour	0.000	0.993	0.007
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.000	0.993	0.007
R46.7 Verbosity and circumstantial detail obscuring reason for contact	0.000	0.993	0.007
R46.6 Undue concern and preoccupation with stressful events	0.000	0.993	0.007
R46.5 Suspiciousness and marked evasiveness	0.000	0.993	0.007
R46.3 Overactivity	0.000	0.993	0.007
R46.1 Bizarre personal appearance	0.000	0.993	0.007
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.000	0.993	0.007
R41.2 Retrograde amnesia	0.000	0.993	0.007
M81.99 Osteoporosis, unspecified (Site unspecified)	0.007	0.993	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.000	0.993	0.007
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.007	0.993	0.000
R46.4 Slowness and poor responsiveness	0.000	0.993	0.007
R44.2 Other hallucinations	0.000	0.993	0.007
H04.2 Epiphora	0.007	0.993	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.007	0.993	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.007	0.993	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.000	0.994	0.006
R43.1 Parosmia	0.000	0.994	0.006
M81.91 Osteoporosis, unspecified (Shoulder region)	0.006	0.994	0.000
R44.0 Auditory hallucinations	0.000	0.994	0.006
M81.93 Osteoporosis, unspecified (Forearm)	0.006	0.994	0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.000	0.994	0.006
R44.3 Hallucinations, unspecified	0.000	0.994	0.006
E66 Obesity	0.000	0.994	0.006
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.006	0.994	0.000
G95.9 Disease of spinal cord, unspecified	0.000	0.994	0.006
F17.8 Other mental and behavioural disorders	0.000	0.994	0.006
F17.7 Residual and late-onset psychotic disorder	0.000	0.994	0.006
F17.6 Amnesic syndrome	0.000	0.994	0.006
F17.5 Psychotic disorder	0.000	0.994	0.006
F17.4 Withdrawal state with delirium	0.000	0.994	0.006
F17.3 Withdrawal state	0.000	0.994	0.006
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.000	0.994	0.006
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.000	0.994	0.006
L08.8 Other specified local infections of skin and subcutaneous tissue	0.000	0.994	0.006
F17.0 Acute intoxication	0.000	0.994	0.005
D69.3 Idiopathic thrombocytopenic purpura	0.006	0.994	0.000
R44.1 Visual hallucinations	0.000	0.995	0.005
R43.2 Parageusia	0.000	0.995	0.005
M22 Disorders of patella	0.005	0.995	0.000
N20 Calculus of kidney and ureter	0.005	0.995	0.000
F17.9 Unspecified mental and behavioural disorder	0.000	0.995	0.005
S43.1 Dislocation of acromioclavicular joint	0.000	0.995	0.005
L00-L08 Infections of the skin and subcutaneous tissue	0.000	0.995	0.005
M81.96 Osteoporosis, unspecified (Lower leg)	0.005	0.995	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.000	0.995	0.005
L08 Other local infections of skin and subcutaneous tissue	0.000	0.995	0.005
M22.8 Other disorders of patella	0.005	0.995	0.000
L05.9 Pilonidal cyst without abscess	0.000	0.995	0.005
E66.1 Drug-induced obesity	0.000	0.995	0.004
L08.0 Pyoderma	0.000	0.995	0.004
E66.0 Obesity due to excess calories	0.000	0.996	0.004
G95.2 Cord compression, unspecified	0.000	0.996	0.004
R41.1 Anterograde amnesia	0.000	0.996	0.004
L05 Pilonidal cyst	0.000	0.996	0.004
M22.2 Patellofemoral disorders	0.004	0.996	0.000
M22.3 Other derangements of patella	0.004	0.996	0.000
D69.4 Other primary thrombocytopenia	0.004	0.996	0.000
M22.1 Recurrent subluxation of patella	0.004	0.996	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.004	0.996	0.000
G95 Other diseases of spinal cord	0.000	0.996	0.004
I34.1 Mitral (valve) prolapse	0.004	0.996	0.000
M81 Osteoporosis without pathological fracture	0.004	0.996	0.000
L00 Staphylococcal scalded skin syndrome	0.000	0.996	0.004
E11.9 Without complications	0.000	0.996	0.004
M65.84 Other synovitis and tenosynovitis (Hand)	0.000	0.996	0.004
N20.0 Calculus of kidney	0.004	0.996	0.000
H04.8 Other disorders of lachrymal system	0.004	0.996	0.000
L03.3 Cellulitis of trunk	0.000	0.996	0.004
L08.1 Erythrasma	0.000	0.996	0.004
D69 Purpura and other haemorrhagic conditions	0.004	0.996	0.000
L01 Impetigo	0.000	0.996	0.004
M22.0 Recurrent dislocation of patella	0.004	0.996	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.004	0.996	0.000
L03 Cellulitis	0.000	0.996	0.004
L03.8 Cellulitis of other sites	0.000	0.996	0.004
H04 Disorders of lachrymal system	0.004	0.996	0.000
R41.3 Other amnesia	0.000	0.996	0.004
K42.0 Umbilical hernia with obstruction, without gangrene	0.003	0.997	0.000
N20.2 Calculus of kidney with calculus of ureter	0.003	0.997	0.000
D69.5 Secondary thrombocytopenia	0.003	0.997	0.000
M22.9 Disorder of patella, unspecified	0.003	0.997	0.000
M81.0 Postmenopausal osteoporosis	0.003	0.997	0.000
H04.6 Other changes in lachrymal passages	0.003	0.997	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.003	0.997	0.000
Z91.6 Personal history of other physical trauma	0.000	0.997	0.003
G95.0 Syringomyelia and syringobulbia	0.000	0.997	0.003
M22.10 Recurrent subluxation of patella, unspecified knee	0.003	0.997	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.997	0.003
L04 Acute lymphadenitis	0.000	0.997	0.003
M94.26 Chondromalacia (Lower leg)	0.003	0.997	0.000
M81.8 Other osteoporosis	0.003	0.997	0.000
M81.6 Localised osteoporosis [Lequesne]	0.003	0.997	0.000
M81.5 Idiopathic osteoporosis	0.003	0.997	0.000
M81.1 Postoophorectomy osteoporosis	0.003	0.997	0.000
N02.9 Unspecified	0.000	0.997	0.003
D69.6 Thrombocytopenia, unspecified	0.003	0.997	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.997	0.003
D69.2 Other nonthrombocytopenic purpura	0.003	0.997	0.000
H17.9 Corneal scar and opacity, unspecified	0.000	0.997	0.003
D69.8 Other specified haemorrhagic conditions	0.003	0.997	0.000
L03.1 Cellulitis of other parts of limb	0.000	0.997	0.003
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.003	0.997	0.000
L01.1 Impetiginisation of other dermatoses	0.000	0.997	0.003
M81.2 Osteoporosis of disuse	0.003	0.997	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.003	0.997	0.000
D69.1 Qualitative platelet defects	0.003	0.997	0.000
G95.8 Other specified diseases of spinal cord	0.000	0.997	0.003
H04.0 Dacryoadenitis	0.003	0.997	0.000
S52.70 Multiple fractures of forearm (closed)	0.003	0.997	0.000
T79.6 Traumatic ischaemia of muscle	0.000	0.997	0.003
N23 Unspecified renal colic	0.003	0.997	0.000
L01.0 Impetigo [any organism] [any site]	0.000	0.997	0.003
R03 Abnormal blood-pressure reading, without diagnosis	0.000	0.997	0.003
G95.1 Vascular myelopathies	0.000	0.997	0.003
T21.3 Burn of third degree of trunk	0.000	0.997	0.003
Z96.6 Presence of orthopaedic joint implants	0.000	0.997	0.003
S82.80 Fractures of other parts of lower leg (closed)	0.003	0.997	0.000
M16.1 Other primary coxarthrosis	0.000	0.997	0.003
M81.08 Postmenopausal osteoporosis (Other)	0.003	0.997	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.003	0.997	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.003	0.997	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.003	0.997	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.003	0.997	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.003	0.997	0.000
S82.00 Fracture of patella (closed)	0.003	0.997	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.003	0.997	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.003	0.997	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.003	0.997	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.003	0.997	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.003	0.997	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.003	0.997	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.003	0.997	0.000
X41.9 Unspecified place	0.003	0.997	0.000
N20-N23 Urolithiasis	0.003	0.997	0.000
N20.9 Urinary calculus, unspecified	0.003	0.997	0.000
Z91 Personal history of risk-factors, not elsewhere classified	0.000	0.997	0.003
E66.9 Obesity, unspecified	0.000	0.997	0.003
M16.9 Coxarthrosis, unspecified	0.000	0.997	0.003
L04.8 Acute lymphadenitis of other sites	0.000	0.997	0.002
L04.3 Acute lymphadenitis of lower limb	0.000	0.997	0.002
L04.1 Acute lymphadenitis of trunk	0.000	0.997	0.002
H04.4 Chronic inflammation of lachrymal passages	0.002	0.997	0.000
G03.9 Meningitis, unspecified	0.003	0.997	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.002	0.997	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.002	0.997	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.002	0.997	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.002	0.997	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.002	0.997	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.002	0.997	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.002	0.997	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.002	0.997	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.002	0.997	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.002	0.997	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.002	0.997	0.000
M81.58 Idiopathic osteoporosis (Other)	0.002	0.997	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.002	0.997	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.002	0.997	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.002	0.997	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.002	0.997	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.002	0.997	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.002	0.997	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.002	0.997	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.002	0.997	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.002	0.997	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.002	0.997	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.002	0.997	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.002	0.997	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.002	0.997	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.002	0.997	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.002	0.997	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.002	0.997	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.002	0.997	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.002	0.997	0.000
M81.89 Other osteoporosis (Site unspecified)	0.002	0.997	0.000
M81.88 Other osteoporosis (Other)	0.002	0.997	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.002	0.997	0.000
M81.86 Other osteoporosis (Lower leg)	0.002	0.997	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.002	0.997	0.000
M81.84 Other osteoporosis (Hand)	0.002	0.997	0.000
M81.83 Other osteoporosis (Forearm)	0.002	0.997	0.000
M81.82 Other osteoporosis (Upper arm)	0.002	0.997	0.000
M81.81 Other osteoporosis (Shoulder region)	0.002	0.997	0.000
M81.80 Other osteoporosis (Multiple sites)	0.002	0.997	0.000
D69.0 Allergic purpura	0.002	0.997	0.000
L04.2 Acute lymphadenitis of upper limb	0.000	0.997	0.002
L04.0 Acute lymphadenitis of face, head and neck	0.000	0.998	0.002
N83.2 Other and unspecified ovarian cysts	0.000	0.998	0.002
R45 Symptoms and signs involving emotional state	0.000	0.998	0.002
E65-E68 Obesity and other hyperalimentation	0.000	0.998	0.002
M81.29 Osteoporosis of disuse (Site unspecified)	0.002	0.998	0.000
M81.28 Osteoporosis of disuse (Other)	0.002	0.998	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.002	0.998	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.002	0.998	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.002	0.998	0.000
M81.24 Osteoporosis of disuse (Hand)	0.002	0.998	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.002	0.998	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.002	0.998	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.002	0.998	0.000
T23.2 Burn of second degree of wrist and hand	0.000	0.998	0.002
H04.1 Other disorders of lachrymal gland	0.002	0.998	0.000
R45.0 Nervousness	0.000	0.998	0.002
T21 Burn and corrosion of trunk	0.000	0.998	0.002
T21.0 Burn of unspecified degree of trunk	0.000	0.998	0.002
H04.3 Acute and unspecified inflammation of lachrymal passages	0.002	0.998	0.000
D69.9 Haemorrhagic condition, unspecified	0.002	0.998	0.000
H04.9 Disorder of lachrymal system, unspecified	0.002	0.998	0.000
S52.40 Fracture of shafts of both ulna and radius (closed)	0.002	0.998	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.002	0.998	0.000
R26.2 Difficulty in walking, not elsewhere classified	0.000	0.998	0.002
M79.86 Other specified soft tissue disorders (Lower leg)	0.000	0.998	0.002
L03.0 Cellulitis of finger and toe	0.000	0.998	0.002
M81.4 Drug-induced osteoporosis	0.002	0.998	0.000
N76.2 Acute vulvitis	0.000	0.998	0.002
M31 Other necrotising vasculopathies	0.002	0.998	0.000
D11.0 Parotid gland	0.002	0.998	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.002	0.998	0.000
E13.9 Without complications	0.002	0.998	0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.000	0.998	0.002
Z91.7 Personal history of female genital mutilation	0.000	0.998	0.002
Z91.3 Personal history of unhealthy sleep-wake schedule	0.000	0.998	0.002
T23 Burn and corrosion of wrist and hand	0.000	0.998	0.002
L04.9 Acute lymphadenitis, unspecified	0.000	0.998	0.002
M65.8 Other synovitis and tenosynovitis	0.000	0.998	0.002
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.000	0.998	0.002
M94.2 Chondromalacia	0.002	0.998	0.000
R03.1 Nonspecific low blood-pressure reading	0.000	0.998	0.002
M65.87 Other synovitis and tenosynovitis (Ankle and foot)	0.000	0.998	0.002
S52.20 Fracture of shaft of ulna (closed)	0.002	0.998	0.000
H04.5 Stenosis and insufficiency of lachrymal passages	0.002	0.998	0.000
M31.3 Wegener's granulomatosis	0.002	0.998	0.000
T23.1 Burn of first degree of wrist and hand	0.000	0.998	0.002
M79.88 Other specified soft tissue disorders (Other)	0.000	0.998	0.002
S52.41 Fracture of shafts of both ulna and radius (open)	0.002	0.998	0.000
K65.9 Peritonitis, unspecified	0.000	0.998	0.002
R45.7 State of emotional shock and stress, unspecified	0.000	0.998	0.002
R45.3 Demoralisation and apathy	0.000	0.998	0.002
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
R45.4 Irritability and anger	0.000	0.998	0.002
Z91.2 Personal history of poor personal hygiene	0.000	0.998	0.002
E67 Other hyperalimentation	0.000	0.998	0.002
E68 Sequelae of hyperalimentation	0.000	0.998	0.002
Z71.9 Counselling, unspecified	0.000	0.998	0.002
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.000	0.998	0.002
T21.7 Corrosion of third degree of trunk	0.000	0.998	0.002
T21.6 Corrosion of second degree of trunk	0.000	0.998	0.002
T21.5 Corrosion of first degree of trunk	0.000	0.998	0.002
T21.4 Corrosion of unspecified degree of trunk	0.000	0.998	0.002
S52.7 Multiple fractures of forearm	0.002	0.998	0.000
S62.50 Fracture of thumb (closed)	0.002	0.998	0.000
S52.4 Fracture of shafts of both ulna and radius	0.002	0.998	0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified	0.000	0.998	0.002
T20-T25 Burns and corrosions of external body surface, specified by site	0.000	0.998	0.002
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.000	0.998	0.002
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
D29.0 Penis	0.000	0.998	0.002
I60.9 Subarachnoid haemorrhage, unspecified	0.002	0.998	0.000
R45.5 Hostility	0.000	0.998	0.002
T25 Burn and corrosion of ankle and foot	0.000	0.998	0.002
M81.48 Drug-induced osteoporosis (Other)	0.002	0.998	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.002	0.998	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.002	0.998	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.002	0.998	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.002	0.998	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.002	0.998	0.000
M31.8 Other specified necrotising vasculopathies	0.002	0.998	0.000
M31.2 Lethal midline granuloma	0.002	0.998	0.000
N22.8 Calculus of urinary tract in other diseases classified elsewhere	0.002	0.998	0.000
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]	0.002	0.998	0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified	0.000	0.998	0.002
T23.7 Corrosion of third degree of wrist and hand	0.000	0.998	0.002
T23.6 Corrosion of second degree of wrist and hand	0.000	0.998	0.002
T23.5 Corrosion of first degree of wrist and hand	0.000	0.998	0.002
T23.4 Corrosion of unspecified degree of wrist and hand	0.000	0.998	0.002
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
E65 Localised adiposity	0.000	0.998	0.002
T21.2 Burn of second degree of trunk	0.000	0.998	0.002
T23.0 Burn of unspecified degree of wrist and hand	0.000	0.998	0.002
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.000	0.998	0.002
M65.89 Other synovitis and tenosynovitis (Site unspecified)	0.000	0.998	0.002
M65.88 Other synovitis and tenosynovitis (Other)	0.000	0.998	0.002
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)	0.000	0.998	0.002
M65.82 Other synovitis and tenosynovitis (Upper arm)	0.000	0.998	0.002
M65.81 Other synovitis and tenosynovitis (Shoulder region)	0.000	0.998	0.002
M65.80 Other synovitis and tenosynovitis (Multiple sites)	0.000	0.998	0.002
M94.29 Chondromalacia (Site unspecified)	0.002	0.998	0.000
M94.28 Chondromalacia (Other)	0.002	0.998	0.000
M94.27 Chondromalacia (Ankle and foot)	0.002	0.998	0.000
M94.25 Chondromalacia (Pelvic region and thigh)	0.002	0.998	0.000
M94.24 Chondromalacia (Hand)	0.002	0.998	0.000
M94.23 Chondromalacia (Forearm)	0.002	0.998	0.000
M94.22 Chondromalacia (Upper arm)	0.002	0.998	0.000
M94.21 Chondromalacia (Shoulder region)	0.002	0.998	0.000
M94.20 Chondromalacia (Multiple sites)	0.002	0.998	0.000
J30.3 Other allergic rhinitis	0.002	0.998	0.000
M31.1 Thrombotic microangiopathy	0.002	0.998	0.000
T21.1 Burn of first degree of trunk	0.000	0.998	0.002
L05.0 Pilonidal cyst with abscess	0.000	0.998	0.002
M16 Coxarthrosis [arthrosis of hip]	0.000	0.998	0.002
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.000	0.998	0.002
M79.89 Other specified soft tissue disorders (Site unspecified)	0.000	0.998	0.002
E11.1 With ketoacidosis	0.000	0.998	0.002
R45.6 Physical violence	0.000	0.998	0.002
Z96.8 Presence of other specified functional implants	0.000	0.998	0.002
E11.5 With peripheral circulatory complications	0.000	0.998	0.002
M31.7 Microscopic polyangiitis	0.002	0.998	0.000
T25.3 Burn of third degree of ankle and foot	0.000	0.998	0.002
Y41.0 Sulphonamides	0.002	0.998	0.000
E67.8 Other specified hyperalimentation	0.000	0.998	0.002
E67.3 Hypervitaminosis D	0.000	0.998	0.002
E67.2 Megavitamin-B6 syndrome	0.000	0.998	0.002
E67.1 Hypercarotenaemia	0.000	0.998	0.002
E67.0 Hypervitaminosis A	0.000	0.998	0.002
M16.6 Other secondary coxarthrosis, bilateral	0.000	0.998	0.002
M31.9 Necrotising vasculopathy, unspecified	0.002	0.998	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.002	0.998	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.002	0.998	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.000	0.998	0.002
M31.0 Hypersensitivity angiitis	0.002	0.998	0.000
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
T25.2 Burn of second degree of ankle and foot	0.000	0.998	0.002
G03 Meningitis due to other and unspecified causes	0.002	0.998	0.000
X41.2 School, other institution and public administrative area	0.002	0.998	0.000
S52.71 Multiple fractures of forearm (open)	0.002	0.998	0.000
S82.8 Fractures of other parts of lower leg	0.002	0.998	0.000
H17 Corneal scars and opacities	0.000	0.998	0.002
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
E11.3 With ophthalmic complications	0.000	0.998	0.002
H17.8 Other corneal scars and opacities	0.000	0.998	0.002
L94.2 Calcinosis cutis	0.002	0.998	0.000
S52.2 Fracture of shaft of ulna	0.002	0.998	0.000
E11 Non-insulin-dependent diabetes mellitus	0.000	0.998	0.002
S22.30 Fracture of rib (closed)	0.000	0.998	0.002
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.000	0.998	0.002
M79.8 Other specified soft tissue disorders	0.000	0.998	0.002
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
T25.0 Burn of unspecified degree of ankle and foot	0.000	0.998	0.002
D29.1 Prostate	0.000	0.998	0.002
E04.1 Non-toxic single thyroid nodule	0.000	0.998	0.002
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.000	0.998	0.002
T25.7 Corrosion of third degree of ankle and foot	0.000	0.998	0.001
T25.6 Corrosion of second degree of ankle and foot	0.000	0.998	0.001
T25.5 Corrosion of first degree of ankle and foot	0.000	0.998	0.001
T25.4 Corrosion of unspecified degree of ankle and foot	0.000	0.998	0.001
T25.1 Burn of first degree of ankle and foot	0.000	0.998	0.001
M81.49 Drug-induced osteoporosis (Site unspecified)	0.001	0.998	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.002	0.998	0.000
S46.3 Injury of muscle and tendon of triceps	0.001	0.998	0.000
M79.79 Fibromyalgia (Site unspecified)	0.000	0.998	0.002
S82.81 Fractures of other parts of lower leg (open)	0.002	0.998	0.000
E07.8 Other specified disorders of thyroid	0.000	0.998	0.002
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.998	0.002
M16.7 Other secondary coxarthrosis	0.000	0.998	0.002
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.998	0.002
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.000	0.998	0.002
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.000	0.998	0.002
M65.83 Other synovitis and tenosynovitis (Forearm)	0.000	0.998	0.001
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.000	0.998	0.001
S43.6 Sprain and strain of sternoclavicular joint	0.000	0.998	0.001
S43.5 Sprain and strain of acromioclavicular joint	0.000	0.998	0.001
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.000	0.998	0.001
S43.2 Dislocation of sternoclavicular joint	0.000	0.998	0.001
E00-E07 Disorders of thyroid gland	0.000	0.998	0.002
M16.4 Posttraumatic coxarthrosis, bilateral	0.000	0.998	0.001
S82.0 Fracture of patella	0.002	0.998	0.000
Z97.8 Presence of other specified devices	0.002	0.998	0.000
S52.21 Fracture of shaft of ulna (open)	0.001	0.998	0.000
D40.0 Prostate	0.000	0.998	0.002
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.000	0.998	0.002
R45.2 Unhappiness	0.000	0.998	0.001
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.000	0.998	0.002
S43.4 Sprain and strain of shoulder joint	0.000	0.998	0.001
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.001	0.998	0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.001	0.998	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.001	0.998	0.000
E34.9 Endocrine disorder, unspecified	0.002	0.998	0.000
G03.8 Meningitis due to other specified causes	0.001	0.998	0.000
G03.2 Benign recurrent meningitis [Mollaret]	0.001	0.998	0.000
G03.1 Chronic meningitis	0.001	0.998	0.000
G03.0 Nonpyogenic meningitis	0.001	0.998	0.000
S62.51 Fracture of thumb (open)	0.001	0.998	0.000
C25.0 Head of pancreas	0.000	0.998	0.002
H17.1 Other central corneal opacity	0.000	0.998	0.001
H17.0 Adherent leukoma	0.000	0.998	0.001
K35.8 Acute appendicitis, other and unspecified	0.000	0.998	0.002
K55.9 Vascular disorder of intestine, unspecified	0.000	0.998	0.002
X41.0 Home	0.001	0.998	0.000
X41.8 Other specified place	0.001	0.998	0.000
X41.7 Farm	0.001	0.998	0.000
X41.6 Industrial and construction area	0.001	0.998	0.000
X41.5 Trade and service area	0.001	0.998	0.000
X41.4 Street and highway	0.001	0.998	0.000
X41.3 Sports and athletics area	0.001	0.998	0.000
X41.1 Residential institution	0.001	0.998	0.000
S82.86 Maisonneuve's fracture	0.001	0.998	0.000
E11.8 With unspecified complications	0.000	0.998	0.001
E11.7 With multiple complications	0.000	0.998	0.001
T23.3 Burn of third degree of wrist and hand	0.000	0.998	0.001
S82.01 Fracture of patella (open)	0.001	0.999	0.000
C09.9 Tonsil, unspecified	0.001	0.999	0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.000	0.999	0.001
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.001	0.999	0.000
E07 Other disorders of thyroid	0.000	0.999	0.001
M79.82 Other specified soft tissue disorders (Upper arm)	0.000	0.999	0.001
C25.2 Tail of pancreas	0.000	0.999	0.001
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.001	0.999	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.001	0.999	0.000
M02.96 Reactive arthropathy, unspecified (Lower leg)	0.001	0.999	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.001	0.999	0.000
K61.0 Anal abscess	0.000	0.999	0.001
M47.96 Spondylosis, unspecified (Lumbar region)	0.000	0.999	0.001
M72.2 Plantar fascial fibromatosis	0.000	0.999	0.001
Z88.2 Personal history of allergy to sulphonamides	0.000	0.999	0.001
G24.5 Blepharospasm	0.000	0.999	0.001
M80.5 Idiopathic osteoporosis with pathological fracture	0.001	0.999	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.999	0.001
E00 Congenital iodine-deficiency syndrome	0.000	0.999	0.001
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.000	0.999	0.001
N21.8 Other lower urinary tract calculus	0.001	0.999	0.000
I60 Subarachnoid haemorrhage	0.001	0.999	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.001	0.999	0.000
S65.1 Injury of radial artery at wrist and hand level	0.001	0.999	0.000
T20 Burn and corrosion of head and neck	0.000	0.999	0.001
M19.97 Arthrosis, unspecified (Ankle and foot)	0.000	0.999	0.001
M79.81 Other specified soft tissue disorders (Shoulder region)	0.000	0.999	0.001
X41.08 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, antiparkinsonism and psychotropic drugs, not elsewhere classified , Home ,While engaged in other specified activities	0.001	0.999	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.999	0.001
E11.0 With coma	0.000	0.999	0.001
H33.3 Retinal breaks without detachment	0.001	0.999	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.001	0.999	0.000
S62.5 Fracture of thumb	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations