TreeWAS – Variant ID: rs2909678

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H35 Other retinal disorders	0.165	0.835	0.000
H35.4 Peripheral retinal degeneration	0.161	0.839	0.000
H30-H36 Disorders of choroid and retina	0.161	0.839	0.000
H33.3 Retinal breaks without detachment	0.160	0.840	0.000
H33 Retinal detachments and breaks	0.159	0.841	0.000
H35.6 Retinal haemorrhage	0.146	0.854	0.000
H18 Other disorders of cornea	0.142	0.858	0.000
H35.9 Retinal disorder, unspecified	0.140	0.860	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.139	0.861	0.000
Chapter VII Diseases of the eye and adnexa	0.138	0.862	0.000
H35.5 Hereditary retinal dystrophy	0.138	0.862	0.000
H40 Glaucoma	0.138	0.862	0.000
H25.0 Senile incipient cataract	0.137	0.863	0.000
H40-H42 Glaucoma	0.137	0.863	0.000
H33.2 Serous retinal detachment	0.132	0.868	0.000
H25 Senile cataract	0.132	0.868	0.000
H25-H28 Disorders of lens	0.131	0.869	0.000
H18.5 Hereditary corneal dystrophies	0.130	0.870	0.000
H35.7 Separation of retinal layers	0.129	0.871	0.000
H40.9 Glaucoma, unspecified	0.128	0.872	0.000
H18.2 Other corneal oedema	0.128	0.872	0.000
H35.8 Other specified retinal disorders	0.127	0.873	0.000
H40.2 Primary angle-closure glaucoma	0.126	0.874	0.000
H33.0 Retinal detachment with retinal break	0.125	0.875	0.000
H40.5 Glaucoma secondary to other eye disorders	0.123	0.877	0.000
H18.1 Bullous keratopathy	0.121	0.879	0.000
H18.6 Keratoconus	0.121	0.879	0.000
H30 Chorioretinal inflammation	0.119	0.881	0.000
H35.1 Retinopathy of prematurity	0.119	0.881	0.000
H34 Retinal vascular occlusions	0.117	0.882	0.000
H35.3 Degeneration of macula and posterior pole	0.117	0.883	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.116	0.884	0.000
H35.2 Other proliferative retinopathy	0.114	0.886	0.000
H33.4 Traction detachment of retina	0.113	0.887	0.000
H25.9 Senile cataract, unspecified	0.112	0.888	0.000
H18.4 Corneal degeneration	0.112	0.888	0.000
H40.8 Other glaucoma	0.111	0.889	0.000
H17 Corneal scars and opacities	0.109	0.891	0.000
H18.7 Other corneal deformities	0.108	0.892	0.000
H21 Other disorders of iris and ciliary body	0.108	0.892	0.000
H40.3 Glaucoma secondary to eye trauma	0.106	0.894	0.000
H25.1 Senile nuclear cataract	0.106	0.894	0.000
H18.0 Corneal pigmentations and deposits	0.105	0.895	0.000
H20 Iridocyclitis	0.105	0.895	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.105	0.895	0.000
H40.1 Primary open-angle glaucoma	0.103	0.897	0.000
H31 Other disorders of choroid	0.103	0.897	0.000
H18.3 Changes in corneal membranes	0.103	0.897	0.000
H18.9 Disorder of cornea, unspecified	0.101	0.899	0.000
H40.6 Glaucoma secondary to drugs	0.100	0.900	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.099	0.901	0.000
H42 Glaucoma in diseases classified elsewhere	0.098	0.902	0.000
H16 Keratitis	0.098	0.902	0.000
H40.4 Glaucoma secondary to eye inflammation	0.096	0.904	0.000
H25.2 Senile cataract, morgagnian type	0.095	0.905	0.000
H34.8 Other retinal vascular occlusions	0.095	0.905	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.093	0.907	0.000
H21.8 Other specified disorders of iris and ciliary body	0.092	0.908	0.000
H34.9 Retinal vascular occlusion, unspecified	0.091	0.908	0.000
H33.5 Other retinal detachments	0.090	0.910	0.000
H30.9 Chorioretinal inflammation, unspecified	0.090	0.910	0.000
H17.8 Other corneal scars and opacities	0.088	0.912	0.000
H35.0 Background retinopathy and retinal vascular changes	0.087	0.913	0.000
H30.8 Other chorioretinal inflammations	0.086	0.914	0.000
H30.1 Disseminated chorioretinal inflammation	0.086	0.914	0.000
H30.0 Focal chorioretinal inflammation	0.086	0.914	0.000
H21.4 Pupillary membranes	0.086	0.914	0.000
H30.2 Posterior cyclitis	0.085	0.915	0.000
H34.0 Transient retinal artery occlusion	0.084	0.915	0.000
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.083	0.917	0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.083	0.917	0.000
H33.1 Retinoschisis and retinal cysts	0.082	0.918	0.000
H20.1 Chronic iridocyclitis	0.082	0.918	0.000
H20.9 Iridocyclitis, unspecified	0.081	0.919	0.000
H27 Other disorders of lens	0.080	0.920	0.000
H36 Retinal disorders in diseases classified elsewhere	0.080	0.920	0.000
H34.1 Central retinal artery occlusion	0.079	0.921	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.079	0.921	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.079	0.921	0.000
H16.9 Keratitis, unspecified	0.079	0.921	0.000
H18.8 Other specified disorders of cornea	0.078	0.921	0.000
H17.1 Other central corneal opacity	0.078	0.922	0.000
H17.0 Adherent leukoma	0.078	0.922	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.078	0.922	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.077	0.923	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.076	0.924	0.000
H55-H59 Other disorders of eye and adnexa	0.076	0.924	0.000
H17.9 Corneal scar and opacity, unspecified	0.076	0.924	0.000
H20.2 Lens-induced iridocyclitis	0.075	0.924	0.000
H31.0 Chorioretinal scars	0.075	0.924	0.000
H20.8 Other iridocyclitis	0.075	0.924	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.075	0.925	0.000
H31.8 Other specified disorders of choroid	0.075	0.925	0.000
H21.2 Degeneration of iris and ciliary body	0.074	0.925	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.074	0.926	0.000
H21.0 Hyphaema	0.074	0.926	0.000
H31.4 Choroidal detachment	0.074	0.926	0.000
H31.2 Hereditary choroidal dystrophy	0.074	0.926	0.000
H16.0 Corneal ulcer	0.074	0.926	0.000
H15 Disorders of sclera	0.073	0.927	0.000
H16.3 Interstitial and deep keratitis	0.073	0.927	0.000
H31.3 Choroidal haemorrhage and rupture	0.073	0.927	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.073	0.927	0.000
H16.8 Other keratitis	0.072	0.927	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.071	0.929	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.071	0.929	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.071	0.929	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.071	0.929	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.070	0.930	0.000
H43-H45 Disorders of vitreous body and globe	0.069	0.931	0.000
H31.1 Choroidal degeneration	0.069	0.931	0.000
H34.2 Other retinal artery occlusions	0.067	0.933	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.067	0.933	0.000
H28.8 Other disorders of lens in diseases classified elsewhere	0.067	0.933	0.000
H28.2 Cataract in other diseases classified elsewhere	0.067	0.933	0.000
H28.1 Cataract in other endocrine, nutritional and metabolic diseases	0.067	0.933	0.000
H20.0 Acute and subacute iridocyclitis	0.066	0.934	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.066	0.934	0.000
H28.0 Diabetic cataract	0.065	0.934	0.000
H31.9 Disorder of choroid, unspecified	0.065	0.934	0.000
H16.2 Keratoconjunctivitis	0.062	0.938	0.000
H27.0 Aphakia	0.060	0.940	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.060	0.940	0.000
H16.4 Corneal neovascularisation	0.058	0.942	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.058	0.942	0.000
H27.9 Disorder of lens, unspecified	0.058	0.942	0.000
H10-H13 Disorders of conjunctiva	0.057	0.942	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.057	0.943	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.054	0.946	0.000
H55 Nystagmus and other irregular eye movements	0.054	0.946	0.000
H15.1 Episcleritis	0.054	0.946	0.000
H27.8 Other specified disorders of lens	0.052	0.948	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.051	0.949	0.000
H53-H54 Visual disturbances and blindness	0.051	0.949	0.000
H15.0 Scleritis	0.050	0.950	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.049	0.951	0.000
H27.1 Dislocation of lens	0.048	0.951	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.048	0.952	0.001
H15.9 Disorder of sclera, unspecified	0.047	0.952	0.001
H46 Optic neuritis	0.047	0.953	0.000
H51 Other disorders of binocular movement	0.047	0.953	0.000
H26 Other cataract	0.046	0.954	0.000
H57 Other disorders of eye and adnexa	0.044	0.956	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.041	0.959	0.000
H44 Disorders of globe	0.040	0.959	0.000
H43 Disorders of vitreous body	0.038	0.960	0.001
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.039	0.961	0.000
H58.1 Visual disturbances in diseases classified elsewhere	0.039	0.961	0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.039	0.961	0.000
H58.8 Visual disturbances in diseases classified elsewhere	0.038	0.961	0.000
I85.9 Oesophageal varices without bleeding	0.000	0.962	0.038
H10 Conjunctivitis	0.038	0.962	0.000
H50 Other strabismus	0.038	0.962	0.000
H51.2 Internuclear ophthalmoplegia	0.037	0.963	0.000
H48.8 Other disorders of optic nerve and visual pathways in diseases classified elsewhere	0.037	0.963	0.000
H48.0 Optic atrophy in diseases classified elsewhere	0.037	0.963	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.037	0.963	0.000
H15.8 Other disorders of sclera	0.036	0.963	0.001
H26.1 Traumatic cataract	0.036	0.964	0.000
H48.1 Retrobulbar neuritis in diseases classified elsewhere	0.036	0.964	0.000
H51.9 Disorder of binocular movement, unspecified	0.036	0.964	0.000
H45.8 Other disorders of vitreous body and globe in diseases classified elsewhere	0.034	0.965	0.001
H45.1 Endophthalmitis in diseases classified elsewhere	0.034	0.965	0.001
H51.8 Other specified disorders of binocular movement	0.034	0.966	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.034	0.966	0.000
H26.2 Complicated cataract	0.034	0.966	0.000
H51.1 Convergence insufficiency and excess	0.034	0.966	0.000
H51.0 Palsy of conjugate gaze	0.034	0.966	0.000
H59.0 Vitreous syndrome following cataract surgery	0.033	0.966	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.033	0.966	0.000
H26.3 Drug-induced cataract	0.033	0.967	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.033	0.967	0.000
H45.0 Vitreous haemorrhage in diseases classified elsewhere	0.032	0.967	0.001
H26.8 Other specified cataract	0.033	0.967	0.000
H43.9 Disorder of vitreous body, unspecified	0.031	0.968	0.001
H44.1 Other endophthalmitis	0.032	0.968	0.000
H13.1 Conjunctivitis in infectious and parasitic diseases classified elsewhere	0.032	0.968	0.000
H43.8 Other disorders of vitreous body	0.032	0.968	0.000
H50.1 Divergent concomitant strabismus	0.031	0.969	0.000
H43.2 Crystalline deposits in vitreous body	0.030	0.969	0.001
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.030	0.970	0.000
H13.8 Other disorders of conjunctiva in diseases classified elsewhere	0.030	0.970	0.000
H13.2 Conjunctivitis in other diseases classified elsewhere	0.030	0.970	0.000
H13.0 Filarial infection of conjunctiva	0.030	0.970	0.000
H44.2 Degenerative myopia	0.030	0.970	0.000
H26.4 After-cataract	0.030	0.970	0.000
H57.1 Ocular pain	0.030	0.970	0.000
K56.4 Other impaction of intestine	0.030	0.970	0.000
H10.1 Acute atopic conjunctivitis	0.029	0.970	0.000
H44.6 Retained (old) intraocular foreign body, magnetic	0.029	0.971	0.000
H44.3 Other degenerative disorders of globe	0.029	0.971	0.000
H50.5 Heterophoria	0.029	0.971	0.000
H49 Paralytic strabismus	0.029	0.971	0.000
H26.0 Infantile, juvenile and presenile cataract	0.029	0.971	0.000
H44.5 Degenerated conditions of globe	0.029	0.971	0.000
H57.8 Other specified disorders of eye and adnexa	0.029	0.971	0.000
H44.8 Other disorders of globe	0.028	0.971	0.000
H50.9 Strabismus, unspecified	0.028	0.972	0.000
H40.0 Glaucoma suspect	0.028	0.972	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.000	0.972	0.028
H10.2 Other acute conjunctivitis	0.027	0.972	0.000
H10.0 Mucopurulent conjunctivitis	0.027	0.972	0.000
H10.5 Blepharoconjunctivitis	0.027	0.973	0.000
H13.3 Ocular pemphigoid	0.027	0.973	0.000
H10.8 Other conjunctivitis	0.027	0.973	0.000
H47.3 Other disorders of optic disk	0.027	0.973	0.000
H44.4 Hypotony of eye	0.027	0.973	0.000
H47.7 Disorder of visual pathways, unspecified	0.026	0.973	0.000
H47.6 Disorders of visual cortex	0.026	0.973	0.000
H47.4 Disorders of optic chiasm	0.026	0.973	0.000
H43.0 Vitreous prolapse	0.026	0.973	0.001
H50.6 Mechanical strabismus	0.026	0.973	0.000
H10.9 Conjunctivitis, unspecified	0.026	0.974	0.000
H10.3 Acute conjunctivitis, unspecified	0.026	0.974	0.000
H50.4 Other and unspecified heterotropia	0.026	0.974	0.000
H10.4 Chronic conjunctivitis	0.026	0.974	0.000
H50.8 Other specified strabismus	0.025	0.975	0.000
H50.3 Intermittent heterotropia	0.025	0.975	0.000
H47.5 Disorders of other visual pathways	0.025	0.975	0.000
H44.9 Disorder of globe, unspecified	0.024	0.975	0.001
H57.0 Anomalies of pupillary function	0.025	0.975	0.000
H44.0 Purulent endophthalmitis	0.024	0.976	0.000
H47.1 Papilloedema, unspecified	0.024	0.976	0.000
H50.0 Convergent concomitant strabismus	0.024	0.976	0.000
H54 Blindness and low vision	0.024	0.976	0.000
H47.2 Optic atrophy	0.023	0.977	0.000
H43.3 Other vitreous opacities	0.022	0.977	0.001
H49.1 Fourth [trochlear] nerve palsy	0.023	0.977	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.022	0.977	0.000
K56 Paralytic ileus and intestinal obstruction without hernia	0.023	0.977	0.000
K56.5 Intestinal adhesions [bands] with obstruction	0.022	0.978	0.000
H50.2 Vertical strabismus	0.022	0.978	0.000
H49.4 Progressive external ophthalmoplegia	0.021	0.978	0.000
H36.0 Diabetic retinopathy	0.021	0.979	0.000
H49.9 Paralytic strabismus, unspecified	0.021	0.979	0.000
H49.3 Total (external) ophthalmoplegia	0.021	0.979	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.979	0.021
H54.7 Unspecified visual loss	0.021	0.979	0.000
H52 Disorders of refraction and accommodation	0.020	0.980	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.980	0.020
H49.8 Other paralytic strabismus	0.019	0.980	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.000	0.980	0.020
H53.8 Other visual disturbances	0.019	0.981	0.000
H53 Visual disturbances	0.018	0.982	0.000
H54.6 Unqualified visual loss, one eye	0.018	0.982	0.000
H49.2 Sixth [abducent] nerve palsy	0.018	0.982	0.000
H52.2 Astigmatism	0.018	0.982	0.000
K56.0 Paralytic ileus	0.018	0.982	0.000
K56.3 Gallstone ileus	0.017	0.982	0.000
H54.3 Unqualified visual loss, both eyes	0.017	0.983	0.000
H54.4 Blindness, one eye	0.017	0.983	0.000
K56.2 Volvulus	0.017	0.983	0.000
H54.2 Low vision, both eyes	0.016	0.983	0.000
K56.1 Intussusception	0.016	0.983	0.000
K56.7 Ileus, unspecified	0.016	0.984	0.000
H52.4 Presbyopia	0.016	0.984	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.000	0.984	0.016
T78.2 Anaphylactic shock, unspecified	0.000	0.984	0.016
T84.3 Mechanical complication of other bone devices, implants and grafts	0.000	0.984	0.016
H54.1 Blindness, one eye, low vision, other eye	0.015	0.985	0.000
H54.5 Low vision, one eye	0.015	0.985	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.000	0.985	0.015
H52.6 Other disorders of refraction	0.015	0.985	0.000
H52.5 Disorders of accommodation	0.015	0.985	0.000
I85 Oesophageal varices	0.000	0.986	0.014
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.000	0.986	0.014
T78 Adverse effects, not elsewhere classified	0.000	0.986	0.014
H53.6 Night blindness	0.013	0.987	0.000
T78.3 Angioneurotic oedema	0.000	0.987	0.013
H53.0 Amblyopia ex anopsia	0.013	0.987	0.000
H53.5 Colour vision deficiencies	0.013	0.987	0.000
H25.8 Other senile cataract	0.013	0.987	0.000
H54.0 Blindness, both eyes	0.012	0.988	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.012	0.988	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.000	0.988	0.012
H52.7 Disorder of refraction, unspecified	0.012	0.988	0.000
H53.3 Other disorders of binocular vision	0.011	0.988	0.000
H53.9 Visual disturbance, unspecified	0.011	0.988	0.000
H43.1 Vitreous haemorrhage	0.002	0.989	0.008
H49.0 Third [oculomotor] nerve palsy	0.010	0.989	0.001
H52.3 Anisometropia and aniseikonia	0.010	0.989	0.000
H11 Other disorders of conjunctiva	0.009	0.990	0.001
T78.8 Other adverse effects, not elsewhere classified	0.000	0.990	0.010
T78.9 Adverse effect, unspecified	0.000	0.990	0.010
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.990	0.010
H52.0 Hypermetropia	0.009	0.991	0.000
H54.9 Unspecified visual impairment (binocular)	0.009	0.991	0.000
I85.0 Oesophageal varices with bleeding	0.000	0.991	0.008
K56.6 Other and unspecified intestinal obstruction	0.008	0.992	0.000
T66-T78 Other and unspecified effects of external causes	0.000	0.992	0.008
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.008	0.992	0.000
H11.8 Other specified disorders of conjunctiva	0.007	0.992	0.001
T68 Hypothermia	0.000	0.993	0.007
H53.2 Diplopia	0.007	0.993	0.000
H11.1 Conjunctival degenerations and deposits	0.007	0.993	0.001
H53.1 Subjective visual disturbances	0.007	0.993	0.000
T75 Effects of other external causes	0.000	0.993	0.007
I81 Portal vein thrombosis	0.000	0.993	0.007
H11.2 Conjunctival scars	0.006	0.993	0.001
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.000	0.994	0.006
H11.4 Other conjunctival vascular disorders and cysts	0.006	0.994	0.001
S01.1 Open wound of eyelid and periocular area	0.000	0.994	0.006
T84.1 Mechanical complication of internal fixation device of bones of limb	0.000	0.994	0.006
T73 Effects of other deprivation	0.000	0.994	0.006
H52.1 Myopia	0.006	0.994	0.000
T71 Asphyxiation	0.000	0.994	0.006
T74 Maltreatment syndromes	0.000	0.994	0.006
T69 Other effects of reduced temperature	0.000	0.994	0.006
T67 Effects of heat and light	0.000	0.994	0.006
H11.9 Disorder of conjunctiva, unspecified	0.005	0.994	0.001
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.006	0.994	0.000
Q61.3 Polycystic kidney, unspecified	0.006	0.994	0.000
T75.4 Effects of electric current	0.000	0.994	0.006
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.000	0.994	0.006
T70 Effects of air pressure and water pressure	0.000	0.994	0.006
T78.4 Allergy, unspecified	0.000	0.994	0.006
T75.1 Drowning and nonfatal submersion	0.000	0.994	0.005
T66 Unspecified effects of radiation	0.000	0.994	0.005
Q61 Cystic kidney disease	0.005	0.995	0.000
H53.4 Visual field defects	0.005	0.995	0.000
Q61.2 Polycystic kidney, adult type	0.005	0.995	0.000
T75.8 Other specified effects of external causes	0.000	0.995	0.005
T75.3 Motion sickness	0.000	0.995	0.005
T75.2 Effects of vibration	0.000	0.995	0.005
T75.0 Effects of lightning	0.000	0.995	0.005
H11.3 Conjunctival haemorrhage	0.004	0.995	0.001
O23.5 Infections of the genital tract in pregnancy	0.000	0.995	0.005
J44.9 Chronic obstructive pulmonary disease, unspecified	0.005	0.995	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.000	0.995	0.005
O23 Infections of genito-urinary tract in pregnancy	0.000	0.995	0.005
T73.3 Exhaustion due to excessive exertion	0.000	0.995	0.005
T73.9 Effect of deprivation, unspecified	0.000	0.995	0.005
T73.8 Other effects of deprivation	0.000	0.995	0.005
T73.2 Exhaustion due to exposure	0.000	0.995	0.005
T73.1 Effects of thirst	0.000	0.995	0.005
T73.0 Effects of hunger	0.000	0.995	0.005
T67.9 Effects of heat and light, unspecified	0.000	0.995	0.004
T67.8 Other effects of heat and light	0.000	0.995	0.004
T67.7 Heat oedema	0.000	0.995	0.004
T67.6 Heat fatigue, transient	0.000	0.995	0.004
T67.5 Heat exhaustion, unspecified	0.000	0.995	0.004
T67.4 Heat exhaustion due to salt depletion	0.000	0.995	0.004
T67.3 Heat exhaustion, anhydrotic	0.000	0.995	0.004
T67.2 Heat cramp	0.000	0.995	0.004
T67.1 Heat syncope	0.000	0.995	0.004
T67.0 Heatstroke and sunstroke	0.000	0.995	0.004
T69.9 Effect of reduced temperature, unspecified	0.000	0.995	0.004
T69.8 Other specified effects of reduced temperature	0.000	0.995	0.004
T69.1 Chilblains	0.000	0.995	0.004
T69.0 Immersion hand and foot	0.000	0.995	0.004
T74.9 Maltreatment syndrome, unspecified	0.000	0.995	0.004
T74.8 Other maltreatment syndromes	0.000	0.995	0.004
T74.3 Psychological abuse	0.000	0.995	0.004
T74.2 Sexual abuse	0.000	0.995	0.004
T74.1 Physical abuse	0.000	0.995	0.004
T74.0 Neglect or abandonment	0.000	0.995	0.004
Q61.9 Cystic kidney disease, unspecified	0.005	0.995	0.000
Q61.0 Congenital single renal cyst	0.005	0.995	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.995	0.005
Q61.4 Renal dysplasia	0.004	0.996	0.000
T70.9 Effect of air pressure and water pressure, unspecified	0.000	0.996	0.004
T70.8 Other effects of air pressure and water pressure	0.000	0.996	0.004
T70.4 Effects of high-pressure fluids	0.000	0.996	0.004
T70.2 Other and unspecified effects of high altitude	0.000	0.996	0.004
T70.1 Sinus barotrauma	0.000	0.996	0.004
T70.0 Otitic barotrauma	0.000	0.996	0.004
H03 Disorders of eyelid in diseases classified elsewhere	0.004	0.996	0.000
E53.8 Deficiency of other specified B group vitamins	0.004	0.996	0.000
H11.0 Pterygium	0.003	0.996	0.001
Q61.8 Other cystic kidney diseases	0.004	0.996	0.000
Q61.1 Polycystic kidney, infantile type	0.004	0.996	0.000
H01 Other inflammation of eyelid	0.004	0.996	0.000
O20.0 Threatened abortion	0.000	0.996	0.004
O23.0 Infections of kidney in pregnancy	0.000	0.996	0.004
T70.3 Caisson disease [decompression sickness]	0.000	0.996	0.004
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.000	0.996	0.004
O20 Haemorrhage in early pregnancy	0.000	0.996	0.004
O23.3 Infections of other parts of urinary tract in pregnancy	0.000	0.996	0.004
O23.2 Infections of urethra in pregnancy	0.000	0.996	0.004
O23.1 Infections of bladder in pregnancy	0.000	0.996	0.004
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.996	0.004
O21.0 Mild hyperemesis gravidarum	0.000	0.996	0.004
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.003	0.996	0.000
Q61.5 Medullary cystic kidney	0.003	0.996	0.000
H05 Disorders of orbit	0.003	0.996	0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere	0.003	0.996	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.000	0.996	0.004
O21 Excessive vomiting in pregnancy	0.000	0.997	0.003
I35.1 Aortic (valve) insufficiency	0.003	0.997	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.003	0.997	0.000
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere	0.003	0.997	0.000
H01.9 Inflammation of eyelid, unspecified	0.003	0.997	0.000
K76.6 Portal hypertension	0.000	0.997	0.003
H01.8 Other specified inflammation of eyelid	0.003	0.997	0.000
H05.4 Enophthalmos	0.003	0.997	0.000
K72.9 Hepatic failure, unspecified	0.000	0.997	0.003
D37.4 Colon	0.003	0.997	0.000
H05.8 Other disorders of orbit	0.003	0.997	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.000	0.997	0.003
H01.0 Blepharitis	0.003	0.997	0.000
H04 Disorders of lachrymal system	0.003	0.997	0.000
H06.3 Other disorders of orbit in diseases classified elsewhere	0.002	0.997	0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.002	0.997	0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.002	0.997	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.003	0.997	0.000
O22 Venous complications in pregnancy	0.000	0.997	0.003
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.003	0.997	0.000
Q60-Q64 Congenital malformations of the urinary system	0.003	0.997	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.997	0.003
H05.3 Deformity of orbit	0.003	0.997	0.000
H05.0 Acute inflammation of orbit	0.003	0.997	0.000
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere	0.002	0.997	0.000
O29 Complications of anaesthesia during pregnancy	0.000	0.997	0.003
O25 Malnutrition in pregnancy	0.000	0.997	0.003
H01.1 Non-infectious dermatoses of eyelid	0.003	0.997	0.000
H04.1 Other disorders of lachrymal gland	0.003	0.997	0.000
O21.9 Vomiting of pregnancy, unspecified	0.000	0.997	0.003
H05.1 Chronic inflammatory disorders of orbit	0.002	0.997	0.000
K85.9 Acute pancreatitis, unspecified	0.003	0.997	0.000
K85.1 Biliary acute pancreatitis	0.003	0.997	0.000
Q05.9 Spina bifida, unspecified	0.003	0.997	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.997	0.003
H04.5 Stenosis and insufficiency of lachrymal passages	0.003	0.997	0.000
E53 Deficiency of other B group vitamins	0.003	0.997	0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
O22.4 Haemorrhoids in pregnancy	0.000	0.997	0.002
H04.0 Dacryoadenitis	0.002	0.997	0.000
H05.9 Disorder of orbit, unspecified	0.002	0.997	0.000
K11.5 Sialolithiasis	0.003	0.997	0.000
O20.8 Other haemorrhage in early pregnancy	0.000	0.997	0.002
O21.8 Other vomiting complicating pregnancy	0.000	0.997	0.002
O22.1 Genital varices in pregnancy	0.000	0.997	0.002
K85 Acute pancreatitis	0.002	0.998	0.000
K70.1 Alcoholic hepatitis	0.000	0.998	0.002
Y83.1 Surgical operation with implant of artificial internal device	0.000	0.998	0.002
H00 Hordeolum and chalazion	0.002	0.998	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.998	0.002
O21.2 Late vomiting of pregnancy	0.000	0.998	0.002
O24 Diabetes mellitus in pregnancy	0.000	0.998	0.002
Q64 Other congenital malformations of urinary system	0.002	0.998	0.000
Q05 Spina bifida	0.002	0.998	0.000
O22.9 Venous complication in pregnancy, unspecified	0.000	0.998	0.002
O22.8 Other venous complications in pregnancy	0.000	0.998	0.002
O22.5 Cerebral venous thrombosis in pregnancy	0.000	0.998	0.002
O22.2 Superficial thrombophlebitis in pregnancy	0.000	0.998	0.002
O26 Maternal care for other conditions predominantly related to pregnancy	0.000	0.998	0.002
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.000	0.998	0.002
Q60 Renal agenesis and other reduction defects of kidney	0.002	0.998	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.002	0.998	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.000	0.998	0.002
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.000	0.998	0.002
O29.8 Other complications of anaesthesia during pregnancy	0.000	0.998	0.002
O29.6 Failed or difficult intubation during pregnancy	0.000	0.998	0.002
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.000	0.998	0.002
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.000	0.998	0.002
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.000	0.998	0.002
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.000	0.998	0.002
O29.1 Cardiac complications of anaesthesia during pregnancy	0.000	0.998	0.002
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.000	0.998	0.002
N72 Inflammatory disease of cervix uteri	0.000	0.998	0.002
Q63 Other congenital malformations of kidney	0.002	0.998	0.000
H04.9 Disorder of lachrymal system, unspecified	0.002	0.998	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.002	0.998	0.000
K85.8 Other acute pancreatitis	0.002	0.998	0.000
K85.2 Alcohol-induced acute pancreatitis	0.002	0.998	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.000	0.998	0.002
K85.3 Drug-induced acute pancreatitis	0.002	0.998	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.998	0.002
Q05.4 Unspecified spina bifida with hydrocephalus	0.002	0.998	0.000
K72 Hepatic failure, not elsewhere classified	0.000	0.998	0.002
D89.3 Immune reconstitution syndrome	0.000	0.998	0.002
K11 Diseases of salivary glands	0.002	0.998	0.000
E53.1 Pyridoxine deficiency	0.002	0.998	0.000
E53.0 Riboflavin deficiency	0.002	0.998	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
E53.9 Vitamin B deficiency, unspecified	0.002	0.998	0.000
H04.6 Other changes in lachrymal passages	0.002	0.998	0.000
K85.0 Idiopathic acute pancreatitis	0.002	0.998	0.000
N85.4 Malposition of uterus	0.000	0.998	0.002
Q05.7 Lumbar spina bifida without hydrocephalus	0.002	0.998	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.998	0.002
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.002	0.998	0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.002	0.998	0.000
O26.0 Excessive weight gain in pregnancy	0.000	0.998	0.002
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.998	0.002
H04.4 Chronic inflammation of lachrymal passages	0.002	0.998	0.000
O28 Abnormal findings on antenatal screening of mother	0.000	0.998	0.002
D37.5 Rectum	0.002	0.998	0.000
H04.8 Other disorders of lachrymal system	0.002	0.998	0.000
H06.2 Dysthyroid exophthalmos	0.001	0.998	0.001
K11.8 Other diseases of salivary glands	0.002	0.998	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
D89.1 Cryoglobulinaemia	0.000	0.998	0.002
Q64.7 Other congenital malformations of bladder and urethra	0.002	0.998	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.002	0.998	0.000
N85.1 Endometrial adenomatous hyperplasia	0.000	0.998	0.002
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.000	0.998	0.002
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.002	0.998	0.000
R09.2 Respiratory arrest	0.002	0.998	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations