TreeWAS – Variant ID: rs2945731

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I84 Haemorrhoids	0.042	0.958	0.000
I84.8 Unspecified haemorrhoids with other complications	0.041	0.959	0.000
I84.9 Unspecified haemorrhoids without complication	0.040	0.960	0.000
I84.1 Internal haemorrhoids with other complications	0.039	0.961	0.000
I84.6 Residual haemorrhoidal skin tags	0.037	0.963	0.000
I84.3 External thrombosed haemorrhoids	0.037	0.963	0.000
I84.0 Internal thrombosed haemorrhoids	0.035	0.965	0.000
I84.5 External haemorrhoids without complication	0.034	0.966	0.000
I84.7 Unspecified thrombosed haemorrhoids	0.031	0.968	0.000
I84.4 External haemorrhoids with other complications	0.023	0.977	0.000
I84.2 Internal haemorrhoids without complication	0.020	0.980	0.000
N81.6 Rectocele	0.019	0.981	0.000
N81 Female genital prolapse	0.017	0.983	0.000
N81.1 Cystocele	0.017	0.983	0.000
N81.4 Uterovaginal prolapse, unspecified	0.017	0.983	0.000
N81.2 Incomplete uterovaginal prolapse	0.016	0.984	0.000
N81.0 Female urethrocele	0.014	0.986	0.000
N81.3 Complete uterovaginal prolapse	0.013	0.987	0.000
N81.9 Female genital prolapse, unspecified	0.013	0.987	0.000
C77.9 Lymph node, unspecified	0.000	0.991	0.009
M24.16 Other articular cartilage disorders (Lower leg)	0.009	0.991	0.000
N81.8 Other female genital prolapse	0.009	0.991	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.009	0.991	0.000
N83.2 Other and unspecified ovarian cysts	0.009	0.991	0.000
M24.1 Other articular cartilage disorders	0.008	0.992	0.000
Z43.2 Attention to ileostomy	0.007	0.993	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.993	0.007
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.007	0.993	0.000
C77.5 Intrapelvic lymph nodes	0.000	0.993	0.007
N83.0 Follicular cyst of ovary	0.007	0.993	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.007	0.993	0.000
C77.8 Lymph nodes of multiple regions	0.000	0.993	0.007
C77.4 Inguinal and lower limb lymph nodes	0.000	0.993	0.007
N83.1 Corpus luteum cyst	0.007	0.993	0.000
N81.5 Vaginal enterocele	0.007	0.993	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.006	0.994	0.000
M24.18 Other articular cartilage disorders (Other)	0.006	0.994	0.000
M24.14 Other articular cartilage disorders (Hand)	0.006	0.994	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.006	0.994	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.006	0.994	0.000
C77.2 Intra-abdominal lymph nodes	0.000	0.994	0.006
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.006	0.994	0.000
M24 Other specific joint derangements	0.006	0.994	0.000
Z43 Attention to artificial openings	0.006	0.994	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.005	0.994	0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.006	0.994	0.000
N83.7 Haematoma of broad ligament	0.005	0.994	0.000
N83.6 Haematosalpinx	0.005	0.994	0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube	0.005	0.994	0.000
Z43.6 Attention to other artificial openings of urinary tract	0.005	0.994	0.000
M24.2 Disorder of ligament	0.005	0.995	0.000
N83.3 Acquired atrophy of ovary and Fallopian tube	0.005	0.995	0.000
C77.1 Intrathoracic lymph nodes	0.000	0.995	0.005
Z43.8 Attention to other artificial openings	0.005	0.995	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.005	0.995	0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified	0.005	0.995	0.000
M24.23 Disorder of ligament (Forearm)	0.005	0.995	0.000
Z43.3 Attention to colostomy	0.005	0.995	0.000
N80.1 Endometriosis of ovary	0.005	0.995	0.000
M24.0 Loose body in joint	0.005	0.995	0.000
Z43.5 Attention to cyctostomy	0.005	0.995	0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube	0.004	0.995	0.000
M24.5 Contracture of joint	0.004	0.996	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.004	0.996	0.000
Z43.9 Attention to unspecified artificial opening	0.004	0.996	0.000
Z43.7 Attention to artificial vagina	0.004	0.996	0.000
Z43.0 Attention to tracheostomy	0.004	0.996	0.000
M24.9 Joint derangement, unspecified	0.004	0.996	0.000
M24.7 Protrusio acetabuli	0.004	0.996	0.000
M24.6 Ankylosis of joint	0.004	0.996	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.004	0.996	0.000
K07 Dentofacial anomalies [including malocclusion]	0.004	0.996	0.000
M24.26 Disorder of ligament (Lower leg)	0.004	0.996	0.000
Z43.4 Attention to other artificial openings of digestive tract	0.004	0.996	0.000
K07.1 Anomalies of jaw-cranial base relationship	0.004	0.996	0.000
N84.1 Polyp of cervix uteri	0.004	0.996	0.000
M24.29 Disorder of ligament (Site unspecified)	0.004	0.996	0.000
M24.28 Disorder of ligament (Other)	0.004	0.996	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.004	0.996	0.000
M24.24 Disorder of ligament (Hand)	0.004	0.996	0.000
M24.22 Disorder of ligament (Upper arm)	0.004	0.996	0.000
M24.21 Disorder of ligament (Shoulder region)	0.004	0.996	0.000
M24.20 Disorder of ligament (Multiple sites)	0.004	0.996	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.004	0.996	0.000
K07.6 Temporomandibular joint disorders	0.004	0.996	0.000
K07.4 Malocclusion, unspecified	0.004	0.996	0.000
Z43.1 Attention to gastrostomy	0.004	0.996	0.000
R09.1 Pleurisy	0.004	0.996	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.004	0.996	0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device	0.004	0.996	0.000
M24.07 Loose body in joint (Ankle and foot)	0.004	0.996	0.000
M24.51 Contracture of joint (Shoulder region)	0.004	0.996	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.004	0.996	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.004	0.996	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.004	0.996	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.004	0.996	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.004	0.996	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.004	0.996	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.004	0.996	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.004	0.996	0.000
M24.01 Loose body in joint (Shoulder region)	0.004	0.996	0.000
K05.3 Chronic periodontitis	0.004	0.996	0.000
K12.2 Cellulitis and abscess of mouth	0.004	0.996	0.000
M24.09 Loose body in joint (Site unspecified)	0.003	0.996	0.000
M24.08 Loose body in joint (Other)	0.003	0.996	0.000
M24.06 Loose body in joint-Lower leg	0.003	0.996	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.003	0.996	0.000
M24.04 Loose body in joint (Hand)	0.003	0.996	0.000
M24.03 Loose body in joint (Forearm)	0.003	0.996	0.000
M24.00 Loose body in joint (Multiple sites)	0.003	0.996	0.000
K07.2 Anomalies of dental arch relationship	0.003	0.996	0.000
Z45.8 Adjustment and management of other implanted devices	0.000	0.996	0.004
I86.4 Gastric varices	0.003	0.996	0.000
M24.59 Contracture of joint (Site unspecified)	0.003	0.997	0.000
M24.58 Contracture of joint (Other)	0.003	0.997	0.000
M24.57 Contracture of joint (Ankle and foot)	0.003	0.997	0.000
M24.56 Contracture of joint (Lower leg)	0.003	0.997	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.003	0.997	0.000
M24.53 Contracture of joint (Forearm)	0.003	0.997	0.000
M24.52 Contracture of joint (Upper arm)	0.003	0.997	0.000
M24.50 Contracture of joint (Multiple sites)	0.003	0.997	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.003	0.997	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.003	0.997	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.003	0.997	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.003	0.997	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.003	0.997	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.003	0.997	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.003	0.997	0.000
M24.68 Ankylosis of joint (Other)	0.003	0.997	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.003	0.997	0.000
M24.66 Ankylosis of joint (Lower leg)	0.003	0.997	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.003	0.997	0.000
M24.64 Ankylosis of joint (Hand)	0.003	0.997	0.000
M24.63 Ankylosis of joint (Forearm)	0.003	0.997	0.000
M24.62 Ankylosis of joint (Upper arm)	0.003	0.997	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.003	0.997	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.003	0.997	0.000
M24.79 Protrusio acetabuli-Site unspec	0.003	0.997	0.000
M24.78 Protrusio acetabuli-Other	0.003	0.997	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.003	0.997	0.000
M24.76 Protrusio acetabuli-Lower leg	0.003	0.997	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.003	0.997	0.000
M24.74 Protrusio acetabuli-Hand	0.003	0.997	0.000
M24.73 Protrusio acetabuli-Forearm	0.003	0.997	0.000
M24.72 Protrusio acetabuli-Upper arm	0.003	0.997	0.000
M24.71 Protrusio acetabuli-Shldr region	0.003	0.997	0.000
M24.70 Protrusio acetabuli-Mult sites	0.003	0.997	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.003	0.997	0.000
M24.98 Joint derangement, unspecified (Other)	0.003	0.997	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.003	0.997	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.003	0.997	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M24.94 Joint derangement, unspecified (Hand)	0.003	0.997	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.003	0.997	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.003	0.997	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.003	0.997	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.003	0.997	0.000
K07.3 Anomalies of tooth position	0.003	0.997	0.000
K07.9 Dentofacial anomaly, unspecified	0.003	0.997	0.000
K07.8 Other dentofacial anomalies	0.003	0.997	0.000
K07.5 Dentofacial functional abnormalities	0.003	0.997	0.000
K07.0 Major anomalies of jaw size	0.003	0.997	0.000
I86 Varicose veins of other sites	0.003	0.997	0.000
M24.02 Loose body in joint (Upper arm)	0.003	0.997	0.000
K12 Stomatitis and related lesions	0.003	0.997	0.000
J32.9 Chronic sinusitis, unspecified	0.003	0.997	0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.003	0.997	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.003	0.997	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.003	0.997	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.003	0.997	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.003	0.997	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.003	0.997	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.003	0.997	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.003	0.997	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.003	0.997	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.003	0.997	0.000
M24.54 Contracture of joint (Hand)	0.003	0.997	0.000
K05 Gingivitis and periodontal diseases	0.003	0.997	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.003	0.997	0.000
K14.0 Glossitis	0.003	0.997	0.000
K00 Disorders of tooth development and eruption	0.003	0.997	0.000
K09 Cysts of oral region, not elsewhere classified	0.003	0.997	0.000
Y52.1 Calcium-channel blockers	0.003	0.997	0.000
N80 Endometriosis	0.003	0.997	0.000
K09.8 Other cysts of oral region, not elsewhere classified	0.003	0.997	0.000
K10 Other diseases of jaws	0.003	0.997	0.000
K04.5 Chronic apical periodontitis	0.003	0.997	0.000
K04 Diseases of pulp and periapical tissues	0.003	0.997	0.000
K04.7 Periapical abscess without sinus	0.003	0.997	0.000
N84 Polyp of female genital tract	0.003	0.997	0.000
K12.3 Oral mucositis (ulcerative)	0.003	0.997	0.000
K09.9 Cyst of oral region, unspecified	0.003	0.997	0.000
K00.6 Disturbances in tooth eruption	0.003	0.997	0.000
I86.3 Vulval varices	0.003	0.997	0.000
I86.2 Pelvic varices	0.003	0.997	0.000
I86.0 Sublingual varices	0.003	0.997	0.000
K00.0 Anodontia	0.003	0.997	0.000
K14 Diseases of tongue	0.003	0.997	0.000
I86.1 Scrotal varices	0.003	0.997	0.000
K10.2 Inflammatory conditions of jaws	0.003	0.997	0.000
I88 Nonspecific lymphadenitis	0.003	0.997	0.000
C77.0 Lymph nodes of head, face and neck	0.000	0.997	0.003
I86.8 Varicose veins of other specified sites	0.002	0.997	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.000	0.997	0.003
K12.0 Recurrent oral aphthae	0.003	0.997	0.000
I82 Other venous embolism and thrombosis	0.003	0.997	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.002	0.997	0.000
K10.8 Other specified diseases of jaws	0.003	0.997	0.000
Y52 Agents primarily affecting the cardiovascular system	0.003	0.997	0.000
I87 Other disorders of veins	0.002	0.997	0.000
K05.2 Acute periodontitis	0.002	0.997	0.000
K05.5 Other periodontal diseases	0.002	0.997	0.000
K05.4 Periodontosis	0.002	0.997	0.000
K05.0 Acute gingivitis	0.002	0.997	0.000
N80.2 Endometriosis of Fallopian tube	0.002	0.998	0.000
N84.8 Polyp of other parts of female genital tract	0.002	0.998	0.000
K03 Other diseases of hard tissues of teeth	0.002	0.998	0.000
I87.8 Other specified disorders of veins	0.002	0.998	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
K04.0 Pulpitis	0.002	0.998	0.000
N80.4 Endometriosis of rectovaginal septum and vagina	0.002	0.998	0.000
I85 Oesophageal varices	0.002	0.998	0.000
K00.9 Disorder of tooth development, unspecified	0.002	0.998	0.000
K00.8 Other disorders of tooth development	0.002	0.998	0.000
K00.7 Teething syndrome	0.002	0.998	0.000
K00.5 Hereditary disturbances in tooth structure, not elsewhere classified	0.002	0.998	0.000
K00.4 Disturbances in tooth formation	0.002	0.998	0.000
K00.3 Mottled teeth	0.002	0.998	0.000
K00.2 Abnormalities of size and form of teeth	0.002	0.998	0.000
K00.1 Supernumerary teeth	0.002	0.998	0.000
N42.9 Disorder of prostate, unspecified	0.000	0.998	0.002
N84.3 Polyp of vulva	0.002	0.998	0.000
K09.1 Developmental (nonodontogenic) cysts of oral region	0.002	0.998	0.000
N80.3 Endometriosis of pelvic peritoneum	0.002	0.998	0.000
N80.6 Endometriosis in cutaneous scar	0.002	0.998	0.000
N80.5 Endometriosis of intestine	0.002	0.998	0.000
K10.9 Disease of jaws, unspecified	0.002	0.998	0.000
K10.3 Alveolitis of jaws	0.002	0.998	0.000
K10.1 Giant cell granuloma, central	0.002	0.998	0.000
K10.0 Developmental disorders of jaws	0.002	0.998	0.000
N84.2 Polyp of vagina	0.002	0.998	0.000
N90 Other noninflammatory disorders of vulva and perineum	0.002	0.998	0.000
K04.4 Acute apical periodontitis of pulpal origin	0.002	0.998	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
N80-N98 Noninflammatory disorders of female genital tract	0.002	0.998	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
K04.3 Abnormal hard tissue formation in pulp	0.002	0.998	0.000
K04.2 Pulp degeneration	0.002	0.998	0.000
K04.1 Necrosis of pulp	0.002	0.998	0.000
N84.9 Polyp of female genital tract, unspecified	0.002	0.998	0.000
K09.2 Other cysts of jaw	0.002	0.998	0.000
I81 Portal vein thrombosis	0.002	0.998	0.000
S81.9 Open wound of lower leg, part unspecified	0.000	0.998	0.002
I51.8 Other ill-defined heart diseases	0.002	0.998	0.000
K04.6 Periapical abscess with sinus	0.002	0.998	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.002	0.998	0.000
K14.6 Glossodynia	0.002	0.998	0.000
K14.5 Plicated tongue	0.002	0.998	0.000
K14.4 Atrophy of tongue papillae	0.002	0.998	0.000
K14.3 Hypertrophy of tongue papillae	0.002	0.998	0.000
K14.2 Median rhomboid glossitis	0.002	0.998	0.000
K14.1 Geographic tongue	0.002	0.998	0.000
I88.8 Other nonspecific lymphadenitis	0.002	0.998	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.002	0.998	0.000
I88.0 Nonspecific mesenteric lymphadenitis	0.002	0.998	0.000
N90.0 Mild vulvar dysplasia	0.002	0.998	0.000
K05.6 Periodontal disease, unspecified	0.002	0.998	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.002	0.998	0.000
K05.1 Chronic gingivitis	0.002	0.998	0.000
Z49.1 Extracorporeal dialysis	0.002	0.998	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.002	0.998	0.000
Z49.0 Preparatory care for dialysis	0.002	0.998	0.000
I82.3 Embolism and thrombosis of renal vein	0.002	0.998	0.000
I82.1 Thrombophlebitis migrans	0.002	0.998	0.000
I82.0 Budd-Chiari syndrome	0.002	0.998	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.002	0.998	0.000
K09.0 Developmental odontogenic cysts	0.002	0.998	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.002	0.998	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
Y52.7 Peripheral vasodilators	0.002	0.998	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
N90.4 Leukoplakia of vulva	0.002	0.998	0.000
I87.9 Disorder of vein, unspecified	0.002	0.998	0.000
I87.0 Postphlebitic syndrome	0.002	0.998	0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.002	0.998	0.000
K05.22 Aggressive periodontitis, generalized	0.002	0.998	0.000
I82.2 Embolism and thrombosis of vena cava	0.002	0.998	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.002	0.998	0.000
K03.9 Disease of hard tissues of teeth, unspecified	0.002	0.998	0.000
K03.8 Other specified diseases of hard tissues of teeth	0.002	0.998	0.000
K03.7 Posteruptive colour changes of dental hard tissues	0.002	0.998	0.000
K03.6 Deposits [accretions] on teeth	0.002	0.998	0.000
K03.5 Ankylosis of teeth	0.002	0.998	0.000
K03.4 Hypercementosis	0.002	0.998	0.000
K03.3 Pathological resorption of teeth	0.002	0.998	0.000
K03.2 Erosion of teeth	0.002	0.998	0.000
K03.1 Abrasion of teeth	0.002	0.998	0.000
K03.0 Excessive attrition of teeth	0.002	0.998	0.000
N90.3 Dysplasia of vulva, unspecified	0.002	0.998	0.000
N80.8 Other endometriosis	0.002	0.998	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.002	0.998	0.000
K14.8 Other diseases of tongue	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
N90.2 Severe vulvar dysplasia, not elsewhere classified	0.002	0.998	0.000
N90.1 Moderate vulvar dysplasia	0.002	0.998	0.000
N98 Complications associated with artificial fertilisation	0.002	0.998	0.000
N91 Absent, scanty and rare menstruation	0.002	0.998	0.000
N96 Habitual aborter	0.002	0.998	0.000
N80.0 Endometriosis of uterus	0.002	0.998	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.002	0.998	0.000
I82.8 Embolism and thrombosis of other specified veins	0.002	0.998	0.000
Z12.1 Special screening examination for neoplasm of intestinal tract	0.002	0.998	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.002	0.998	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.002	0.998	0.000
L30.9 Dermatitis, unspecified	0.002	0.998	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.002	0.998	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
I85.9 Oesophageal varices without bleeding	0.002	0.998	0.000
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified	0.002	0.998	0.000
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma	0.002	0.998	0.000
K06.1 Gingival enlargement	0.002	0.998	0.000
K06.0 Gingival recession	0.002	0.998	0.000
I45.1 Other and unspecified right bundle-branch block	0.000	0.998	0.002
I85.0 Oesophageal varices with bleeding	0.002	0.998	0.000
I87.1 Compression of vein	0.002	0.998	0.000
K12.1 Other forms of stomatitis	0.002	0.998	0.000
N80.9 Endometriosis, unspecified	0.002	0.998	0.000
R22.2 Localised swelling, mass and lump, trunk	0.000	0.998	0.002
Z49 Care involving dialysis	0.002	0.998	0.000
N82 Fistulae involving female genital tract	0.002	0.998	0.000
K13 Other diseases of lip and oral mucosa	0.002	0.998	0.000
T51.0 Ethanol	0.000	0.998	0.002
Z49.2 Other dialysis	0.002	0.998	0.000
N91.5 Oligomenorrhoea, unspecified	0.001	0.998	0.000
N91.4 Secondary oligomenorrhoea	0.001	0.998	0.000
N91.3 Primary oligomenorrhoea	0.001	0.998	0.000
N91.2 Amenorrhoea, unspecified	0.001	0.998	0.000
N91.1 Secondary amenorrhoea	0.001	0.998	0.000
N91.0 Primary amenorrhoea	0.001	0.998	0.000
N98.9 Complication associated with artificial fertilisation, unspecified	0.001	0.998	0.000
N98.8 Other complications associated with artificial fertilisation	0.001	0.998	0.000
N98.3 Complications of attempted introduction of embryo in embryo transfer	0.001	0.998	0.000
N98.2 Complications of attempted introduction of fertilised ovum following in vitro fertilisation	0.001	0.998	0.000
N98.1 Hyperstimulation of ovaries	0.001	0.998	0.000
N98.0 Infection associated with artificial insemination	0.001	0.998	0.000
N90.6 Hypertrophy of vulva	0.001	0.998	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.002	0.998	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.002	0.998	0.000
C77.3 Axillary and upper limb lymph nodes	0.000	0.998	0.002
K13.0 Diseases of lips	0.002	0.998	0.000
K01 Embedded and impacted teeth	0.002	0.998	0.000
K14.9 Disease of tongue, unspecified	0.001	0.998	0.000
N21.0 Calculus in bladder	0.000	0.998	0.002
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.001	0.998	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.001	0.998	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.001	0.998	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.001	0.998	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.001	0.998	0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.002	0.998	0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.000	0.998	0.002
N97 Female infertility	0.001	0.998	0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.002	0.998	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.002	0.998	0.000
N90.5 Atrophy of vulva	0.001	0.998	0.000
N95.8 Other specified menopausal and perimenopausal disorders	0.002	0.998	0.000
I83 Varicose veins of lower extremities	0.002	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.001	0.998	0.000
K31.9 Disease of stomach and duodenum, unspecified	0.002	0.998	0.000
N82.9 Female genital tract fistula, unspecified	0.001	0.998	0.000
N82.8 Other female genital tract fistulae	0.001	0.998	0.000
N82.5 Female genital tract-skin fistulae	0.001	0.998	0.000
N82.4 Other female intestinal-genital tract fistulae	0.001	0.998	0.000
N82.2 Fistula of vagina to small intestine	0.001	0.998	0.000
N82.1 Other female urinary-genital tract fistulae	0.001	0.998	0.000
N82.0 Vesicovaginal fistula	0.001	0.998	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.001	0.998	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.001	0.998	0.000
K08 Other disorders of teeth and supporting structures	0.002	0.998	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.001	0.998	0.000
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue	0.001	0.998	0.000
K13.5 Oral submucous fibrosis	0.001	0.998	0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.001	0.998	0.000
K13.3 Hairy leukoplakia	0.001	0.998	0.000
K13.1 Cheek and lip biting	0.001	0.998	0.000
S81.8 Open wound of other parts of lower leg	0.000	0.998	0.001
S81 Open wound of lower leg	0.000	0.998	0.002
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.998	0.002
I89.1 Lymphangitis	0.001	0.998	0.000
K04.8 Radicular cyst	0.001	0.998	0.000
L30.8 Other specified dermatitis	0.001	0.998	0.000
N48.8 Other specified disorders of penis	0.000	0.998	0.001
R09.3 Abnormal sputum	0.001	0.998	0.000
S61.1 Open wound of finger(s) with damage to nail	0.001	0.998	0.000
Z45.1 Adjustment and management of infusion pump	0.000	0.998	0.001
D23.5 Skin of trunk	0.000	0.998	0.001
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.000	0.998	0.001
Y45.2 Propionic acid derivatives	0.001	0.998	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
C18.9 Colon, unspecified	0.000	0.999	0.001
Q51.8 Other congenital malformations of uterus and cervix	0.001	0.999	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.001	0.999	0.000
M47.82 Other spondylosis (Cervical region)	0.001	0.999	0.000
G03.9 Meningitis, unspecified	0.001	0.999	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.001	0.999	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.001	0.999	0.000
S81.0 Open wound of knee	0.000	0.999	0.001
N89.6 Tight hymenal ring	0.001	0.999	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.001	0.999	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.001	0.999	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.001	0.999	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.001	0.999	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.001	0.999	0.000
K13.6 Irritative hyperplasia of oral mucosa	0.001	0.999	0.000
N20.2 Calculus of kidney with calculus of ureter	0.000	0.999	0.001
Z39.0 Care and examination immediately after delivery	0.001	0.999	0.000
K02 Dental caries	0.001	0.999	0.000
Y44 Agents primarily affecting blood constituents	0.001	0.999	0.000
H36.0 Diabetic retinopathy	0.001	0.999	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.001	0.999	0.000
N97.8 Female infertility of other origin	0.001	0.999	0.000
N97.4 Female infertility associated with male factors	0.001	0.999	0.000
N97.3 Female infertility of cervical origin	0.001	0.999	0.000
N97.2 Female infertility of uterine origin	0.001	0.999	0.000
N97.0 Female infertility associated with anovulation	0.001	0.999	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.001	0.999	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.001	0.999	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.999	0.000
Y53.7 Emetics	0.001	0.999	0.000
Y53.6 Antidiarrhoeal drugs	0.001	0.999	0.000
Y53.5 Digestants	0.001	0.999	0.000
Y53.4 Other laxatives	0.001	0.999	0.000
Y53.3 Saline and osmotic laxatives	0.001	0.999	0.000
Y53.2 Stimulant laxatives	0.001	0.999	0.000
Y53.0 Histamine H2-receptor antagonists	0.001	0.999	0.000
M47.84 Other spondylosis (Thoracic region)	0.001	0.999	0.000
N97.1 Female infertility of tubal origin	0.001	0.999	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.001	0.999	0.000
K13.29 Other disturbances of oral epithelium, including tongue	0.001	0.999	0.000
M47.86 Other spondylosis (Lumbar region)	0.001	0.999	0.000
I77.1 Stricture of artery	0.001	0.999	0.000
K08.0 Exfoliation of teeth due to systemic causes	0.001	0.999	0.000
K72.9 Hepatic failure, unspecified	0.000	0.999	0.001
R09.2 Respiratory arrest	0.001	0.999	0.000
S81.7 Multiple open wounds of lower leg	0.000	0.999	0.001
Y51 Drugs primarily affecting the autonomic nervous system	0.001	0.999	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.001	0.999	0.000
N20.1 Calculus of ureter	0.000	0.999	0.001
N82.3 Fistula of vagina to large intestine	0.001	0.999	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.001	0.999	0.000
L30 Other dermatitis	0.001	0.999	0.000
N89 Other noninflammatory disorders of vagina	0.001	0.999	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.001	0.999	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.001	0.999	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.001	0.999	0.000
Y44.2 Anticoagulants	0.001	0.999	0.000
Y59 Other and unspecified vaccines and biological substances	0.001	0.999	0.000
Y58 Bacterial vaccines	0.001	0.999	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.001	0.999	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.001	0.999	0.000
Y48 Anaesthetics and therapeutic gases	0.001	0.999	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.001	0.999	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.001	0.999	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.001	0.999	0.000
M47.8 Other spondylosis	0.001	0.999	0.000
Y42.9 Other and unspecified hormone antagonists	0.001	0.999	0.000
Y42.4 Oral contraceptives	0.001	0.999	0.000
Y42.2 Antithyroid drugs	0.001	0.999	0.000
Y42.1 Thyroid hormones and substitutes	0.001	0.999	0.000
Y56.9 Topical agent, unspecified	0.001	0.999	0.000
Y56.8 Other topical agents	0.001	0.999	0.000
Y56.7 Dental drugs, topically applied	0.001	0.999	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.001	0.999	0.000
Y56.5 Ophthalmological drugs and preparations	0.001	0.999	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.001	0.999	0.000
Y56.3 Emollients, demulcents and protectants	0.001	0.999	0.000
Y56.2 Local astringents and local detergents	0.001	0.999	0.000
Y56.1 Antipruritics	0.001	0.999	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.001	0.999	0.000
J38.1 Polyp of vocal cord and larynx	0.001	0.999	0.000
N95.2 Postmenopausal atrophic vaginitis	0.001	0.999	0.000
K02.5 Caries with pulp exposure	0.001	0.999	0.000
K02.4 Odontoclasia	0.001	0.999	0.000
K02.3 Arrested dental caries	0.001	0.999	0.000
K02.2 Caries of cementum	0.001	0.999	0.000
K02.1 Caries of dentin	0.001	0.999	0.000
K02.0 Caries limited to enamel	0.001	0.999	0.000
K08.2 Atrophy of edentulous alveolar ridge	0.001	0.999	0.000
T21.2 Burn of second degree of trunk	0.001	0.999	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.001	0.999	0.000
Y44.7 Plasma substitutes	0.001	0.999	0.000
Y44.6 Natural blood and blood products	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations