TreeWAS – Variant ID: rs2978048

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N84.1 Polyp of cervix uteri	0.123	0.877	0.000
N84 Polyp of female genital tract	0.101	0.899	0.000
N84.0 Polyp of corpus uteri	0.094	0.906	0.000
Z95.0 Presence of cardiac pacemaker	0.091	0.909	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.090	0.910	0.000
Z95.1 Presence of aortocoronary bypass graft	0.090	0.910	0.000
N84.2 Polyp of vagina	0.081	0.919	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.081	0.919	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.080	0.920	0.000
N84.8 Polyp of other parts of female genital tract	0.077	0.923	0.000
Z95.2 Presence of prosthetic heart valve	0.076	0.924	0.000
N84.3 Polyp of vulva	0.076	0.924	0.000
N84.9 Polyp of female genital tract, unspecified	0.073	0.927	0.000
Z95.3 Presence of xenogenic heart valve	0.071	0.929	0.000
Z95.4 Presence of other heart-valve replacement	0.059	0.941	0.000
Z43.2 Attention to ileostomy	0.037	0.963	0.000
Z43 Attention to artificial openings	0.034	0.966	0.000
N18.9 Chronic renal failure, unspecified	0.000	0.969	0.031
Z43.6 Attention to other artificial openings of urinary tract	0.031	0.969	0.000
Z43.3 Attention to colostomy	0.030	0.970	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.029	0.971	0.000
N18 Chronic renal failure	0.000	0.973	0.027
Z43.4 Attention to other artificial openings of digestive tract	0.026	0.974	0.000
Z43.8 Attention to other artificial openings	0.026	0.974	0.000
N18.4 Chronic kidney disease, stage 4	0.000	0.975	0.025
Z43.9 Attention to unspecified artificial opening	0.024	0.976	0.000
Z43.7 Attention to artificial vagina	0.024	0.976	0.000
Z43.0 Attention to tracheostomy	0.024	0.976	0.000
Z43.5 Attention to cyctostomy	0.024	0.976	0.000
Z43.1 Attention to gastrostomy	0.024	0.976	0.000
N18.3 Chronic kidney disease, stage 3	0.000	0.978	0.022
N18.8 Other chronic renal failure	0.000	0.979	0.021
N18.0 End-stage renal disease	0.000	0.979	0.021
N18.2 Chronic kidney disease, stage 2	0.000	0.979	0.020
N18.5 Chronic kidney disease, stage 5	0.000	0.980	0.020
N18.1 Chronic kidney disease, stage 1	0.000	0.980	0.020
Z50.1 Other physical therapy	0.011	0.989	0.000
Z50 Care involving use of rehabilitation procedures	0.010	0.990	0.000
Z40-Z54 Persons encountering health services for specific procedures and health care	0.009	0.991	0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.009	0.991	0.000
Z46 Fitting and adjustment of other devices	0.008	0.992	0.000
Z45.0 Adjustment and management of cardiac pacemaker	0.008	0.992	0.000
Z52 Donors of organs and tissues	0.008	0.992	0.000
Z41 Procedures for purposes other than remedying health state	0.008	0.992	0.000
Z50.2 Alcohol rehabilitation	0.008	0.992	0.000
Z50.4 Psychotherapy, not elsewhere classified	0.007	0.993	0.000
Z49 Care involving dialysis	0.007	0.993	0.000
Z40 Prophylactic surgery	0.007	0.993	0.000
Z45 Adjustment and management of implanted device	0.007	0.993	0.000
Z50.6 Orthoptic training	0.007	0.993	0.000
Z50.3 Drug rehabilitation	0.007	0.993	0.000
Z50.5 Speech therapy	0.007	0.993	0.000
Z46.8 Fitting and adjustment of other specified devices	0.007	0.993	0.000
Z42 Follow-up care involving plastic surgery	0.007	0.993	0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances	0.007	0.993	0.000
Z46.7 Fitting and adjustment of orthopaedic device	0.007	0.993	0.000
Z52.4 Kidney donor	0.007	0.993	0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.007	0.993	0.000
N17-N19 Renal failure	0.000	0.994	0.006
Z46.9 Fitting and adjustment of other unspecified device	0.006	0.994	0.000
Z46.4 Fitting and adjustment of orthodontic device	0.006	0.994	0.000
Z46.1 Fitting and adjustment of hearing aid	0.006	0.994	0.000
Z46.0 Fitting and adjustment of spectacles and contact lenses	0.006	0.994	0.000
Z44 Fitting and adjustment of external prosthetic device	0.006	0.994	0.000
Z52.3 Bone marrow donor	0.006	0.994	0.000
Z46.3 Fitting and adjustment of dental prosthetic device	0.006	0.994	0.000
Z54 Convalescence	0.006	0.994	0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.006	0.994	0.000
Z49.1 Extracorporeal dialysis	0.006	0.994	0.000
Z50.8 Care involving use of rehabilitation procedures	0.006	0.994	0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses	0.006	0.994	0.000
Z50.0 Cardiac rehabilitation	0.006	0.994	0.000
Z52.9 Donor of unspecified organ or tissue	0.006	0.994	0.000
Z52.8 Donor of other organs and tissues	0.006	0.994	0.000
Z52.7 Heart donor	0.006	0.994	0.000
Z52.6 Liver donor	0.006	0.994	0.000
Z52.5 Cornea donor	0.006	0.994	0.000
Z52.2 Bone donor	0.006	0.994	0.000
Z52.1 Skin donor	0.006	0.994	0.000
Z52.0 Blood donor	0.006	0.994	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.006	0.994	0.000
Z41.9 Procedures for purposes other than remedying health state, unspecified	0.006	0.994	0.000
Z41.8 Other procedures for purposes other than remedying health state	0.006	0.994	0.000
Z41.3 Ear piercing	0.006	0.994	0.000
Z41.2 Routine and ritual circumcision	0.006	0.994	0.000
Z41.0 Hair transplant	0.006	0.994	0.000
Z49.2 Other dialysis	0.006	0.994	0.000
Z42.9 Follow-up care involving plastic surgery, unspecified	0.006	0.994	0.000
Z45.2 Adjustment and management of vascular access device	0.006	0.994	0.000
Z40.8 Other prophylactic surgery	0.005	0.994	0.000
Z40.9 Prophylactic surgery, unspecified	0.005	0.995	0.000
Z45.9 Adjustment and management of unspecified implanted device	0.005	0.995	0.000
Z45.3 Adjustment and management of implanted hearing device	0.005	0.995	0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.005	0.995	0.000
Z42.8 Follow-up care involving plastic surgery of other body part	0.005	0.995	0.000
Y52.1 Calcium-channel blockers	0.005	0.995	0.000
Z49.0 Preparatory care for dialysis	0.005	0.995	0.000
G93.3 Postviral fatigue syndrome	0.000	0.995	0.005
Z42.4 Follow-up care involving plastic surgery of lower extremity	0.005	0.995	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.005	0.995	0.000
Z46.6 Fitting and adjustment of urinary device	0.005	0.995	0.000
Y52 Agents primarily affecting the cardiovascular system	0.005	0.995	0.000
Z44.9 Fitting and adjustment of unspecified external prosthetic device	0.004	0.995	0.000
Z44.8 Fitting and adjustment of other external prosthetic devices	0.004	0.995	0.000
Z44.2 Fitting and adjustment of artificial eye	0.004	0.995	0.000
Z44.1 Fitting and adjustment of artificial leg (complete)(partial)	0.004	0.995	0.000
Z44.0 Fitting and adjustment of artificial arm (complete)(partial)	0.004	0.995	0.000
Z54.9 Convalescence following unspecified treatment	0.004	0.995	0.000
Z54.8 Convalescence following other treatment	0.004	0.995	0.000
Z54.7 Convalescence following combined treatment	0.004	0.995	0.000
Z54.4 Convalescence following treatment of fracture	0.004	0.995	0.000
Z54.3 Convalescence following psychotherapy	0.004	0.995	0.000
Z54.2 Convalescence following chemotherapy	0.004	0.995	0.000
Z54.1 Convalescence following radiotherapy	0.004	0.995	0.000
Z47 Other orthopaedic follow-up care	0.004	0.995	0.001
N17 Acute renal failure	0.000	0.995	0.004
Z42.1 Follow-up care involving plastic surgery of breast	0.004	0.996	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.004	0.996	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.004	0.996	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.004	0.996	0.000
Z75.3 Unavailability and inaccessibility of health-care facilities	0.004	0.996	0.000
Z75 Problems related to medical facilities and other health care	0.004	0.996	0.000
Z12.1 Special screening examination for neoplasm of intestinal tract	0.004	0.996	0.000
Z44.3 Fitting and adjustment of external breast prosthesis	0.003	0.996	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.004	0.996	0.000
Z54.0 Convalescence following surgery	0.003	0.996	0.000
Z48 Other surgical follow-up care	0.004	0.996	0.000
Z75.1 Person awaiting admission to adequate facility elsewhere	0.004	0.996	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.000	0.996	0.004
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.004	0.996	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.004	0.996	0.000
Y52.7 Peripheral vasodilators	0.004	0.996	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.004	0.996	0.000
Z09.8 Follow-up examination after other treatment for other conditions	0.004	0.996	0.000
N17.9 Acute renal failure, unspecified	0.000	0.996	0.004
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.996	0.000
Z47.9 Orthopaedic follow-up care, unspecified	0.003	0.996	0.001
N17.8 Other acute renal failure	0.000	0.996	0.003
N17.2 Acute renal failure with medullary necrosis	0.000	0.996	0.003
N17.1 Acute renal failure with acute cortical necrosis	0.000	0.996	0.003
Z30.5 Surveillance of (intra-uterine) contraceptive device	0.003	0.997	0.000
Z75.5 Holiday relief care	0.003	0.997	0.000
Z75.4 Unavailability and inaccessibility of other helping agencies	0.003	0.997	0.000
L03.1 Cellulitis of other parts of limb	0.000	0.997	0.003
Z45.1 Adjustment and management of infusion pump	0.002	0.997	0.001
Z47.8 Other specified orthopaedic follow-up care	0.003	0.997	0.001
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.003	0.997	0.000
N17.0 Acute renal failure with tubular necrosis	0.000	0.997	0.003
Z75.9 Unspecified problem related to medical facilities and other health care	0.003	0.997	0.000
Z75.2 Other waiting period for investigation and treatment	0.003	0.997	0.000
Z75.0 Medical services not available in home	0.003	0.997	0.000
Z75.8 Other problems related to medical facilities and other health care	0.003	0.997	0.000
Z71.6 Tobacco abuse counselling	0.003	0.997	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.003	0.997	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.003	0.997	0.000
N03.9 Unspecified	0.000	0.997	0.003
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.003	0.997	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.003	0.997	0.000
Z71.9 Counselling, unspecified	0.003	0.997	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.003	0.997	0.000
I21.4 Acute subendocardial myocardial infarction	0.003	0.997	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.000	0.997	0.003
Z71.8 Other specified counselling	0.003	0.997	0.000
Z76 Persons encountering health services in other circumstances	0.003	0.997	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.003	0.997	0.000
Z57 Occupational exposure to risk-factors	0.003	0.997	0.000
Z48.9 Surgical follow-up care, unspecified	0.003	0.997	0.000
H40.9 Glaucoma, unspecified	0.000	0.997	0.003
Z36.0 Antenatal screening for chromosomal anomalies	0.000	0.997	0.003
Z76.9 Persons encountering health services in unspecified circumstances	0.002	0.997	0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.000	0.997	0.002
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.002	0.997	0.000
Z48.0 Attention to surgical dressings and sutures	0.002	0.997	0.000
Z71.7 Human immunodeficiency virus [HIV] counselling	0.002	0.997	0.000
Z71.5 Drug abuse counselling and surveillance	0.002	0.997	0.000
Z71.4 Alcohol abuse counselling and surveillance	0.002	0.997	0.000
Z71.0 Person consulting on behalf of another person	0.002	0.997	0.000
Z71.1 Person with feared complaint in whom no diagnosis is made	0.002	0.997	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.002	0.998	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.002	0.998	0.000
N83.0 Follicular cyst of ovary	0.002	0.998	0.000
D23.5 Skin of trunk	0.000	0.998	0.002
Z57.3 Occupational exposure to other air contaminants	0.002	0.998	0.000
Z76.3 Healthy person accompanying sick person	0.002	0.998	0.000
Z12 Special screening examination for neoplasms	0.002	0.998	0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.002	0.998	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.002	0.998	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.002	0.998	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.002	0.998	0.000
Z71.3 Dietary counselling and surveillance	0.002	0.998	0.000
Z70 Counselling related to sexual attitude, behaviour and orientation	0.002	0.998	0.000
Z36 Antenatal screening	0.000	0.998	0.002
Z71.2 Person consulting for explanation of investigation findings	0.002	0.998	0.000
Z58 Problems related to physical environment	0.002	0.998	0.000
Z12.9 Special screening examination for neoplasm, unspecified	0.002	0.998	0.000
Z76.8 Persons encountering health services in other specified circumstances	0.002	0.998	0.000
Z76.5 Malingerer [conscious situation]	0.002	0.998	0.000
Z76.4 Other boarder in health-care facility	0.002	0.998	0.000
Z76.2 Health supervision and care of other healthy infant and child	0.002	0.998	0.000
Z76.1 Health supervision and care of foundling	0.002	0.998	0.000
Z76.0 Issue of repeat prescription	0.002	0.998	0.000
R17 Unspecified jaundice	0.000	0.998	0.002
Z61 Problems related to negative life events in childhood	0.002	0.998	0.000
N03 Chronic nephritic syndrome	0.000	0.998	0.002
N83.1 Corpus luteum cyst	0.002	0.998	0.000
Z58.1 Exposure to air pollution	0.002	0.998	0.000
K07.1 Anomalies of jaw-cranial base relationship	0.002	0.998	0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.001	0.998	0.001
K00.6 Disturbances in tooth eruption	0.002	0.998	0.000
Z12.4 Special screening examination for neoplasm of cervix	0.002	0.998	0.000
N19 Unspecified renal failure	0.000	0.998	0.002
Z12.8 Special screening examination for neoplasm of other sites	0.002	0.998	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.002	0.998	0.000
Z57.8 Occupational exposure to other risk-factors	0.002	0.998	0.000
Z57.7 Occupational exposure to vibration	0.002	0.998	0.000
Z57.6 Occupational exposure to extreme temperature	0.002	0.998	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.002	0.998	0.000
Z57.1 Occupational exposure to radiation	0.002	0.998	0.000
Z57.0 Occupational exposure to noise	0.002	0.998	0.000
Z56 Problems related to employment and unemployment	0.002	0.998	0.000
Z73 Problems related to life-management difficulty	0.002	0.998	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.002	0.998	0.000
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.002	0.998	0.000
Z59 Problems related to housing and economic circumstances	0.002	0.998	0.000
E53.8 Deficiency of other specified B group vitamins	0.002	0.998	0.000
Z36.8 Other antenatal screening	0.000	0.998	0.002
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.002	0.998	0.000
Chapter XXI Factors influencing health status and contact with health services	0.002	0.998	0.000
Z57.2 Occupational exposure to dust	0.002	0.998	0.000
L03.2 Cellulitis of face	0.000	0.998	0.002
Y44.2 Anticoagulants	0.002	0.998	0.000
Z36.2 Other antenatal screening based on amniocentesis	0.000	0.998	0.002
Z65 Problems related to other psychosocial circumstances	0.002	0.998	0.000
Z63 Other problems related to primary support group, including family circumstances	0.002	0.998	0.000
Z62 Other problems related to upbringing	0.002	0.998	0.000
Z55 Problems related to education and literacy	0.002	0.998	0.000
D21.2 Connective and other soft tissue of lower limb, including hip	0.002	0.998	0.000
Z12.6 Special screening examination for neoplasm of bladder	0.002	0.998	0.000
Z12.3 Special screening examination for neoplasm of breast	0.002	0.998	0.000
Z12.2 Special screening examination for neoplasm of respiratory organs	0.002	0.998	0.000
Z36.9 Antenatal screening, unspecified	0.000	0.998	0.002
K07 Dentofacial anomalies [including malocclusion]	0.002	0.998	0.000
L03 Cellulitis	0.000	0.998	0.002
T43.2 Other and unspecified antidepressants	0.002	0.998	0.000
K07.4 Malocclusion, unspecified	0.002	0.998	0.000
Z73.6 Limitation of activities due to disability	0.002	0.998	0.000
Z99.8 Dependence on other enabling machines and devices	0.002	0.998	0.000
Z70.9 Sex counselling, unspecified	0.002	0.998	0.000
Z70.8 Other sex counselling	0.002	0.998	0.000
Z70.3 Counselling related to combined concerns regarding sexual attitude, behaviour and orientation	0.002	0.998	0.000
Z70.2 Counselling related to sexual behaviour and orientation of third party	0.002	0.998	0.000
Z70.1 Counselling related to patient's sexual behaviour and orientation	0.002	0.998	0.000
Z70.0 Counselling related to sexual attitude	0.002	0.998	0.000
Z64 Problems related to certain psychosocial circumstances	0.002	0.998	0.000
K10.8 Other specified diseases of jaws	0.002	0.998	0.000
T23.2 Burn of second degree of wrist and hand	0.002	0.998	0.000
Z36.5 Antenatal screening for isoimmunisation	0.000	0.998	0.002
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.000	0.998	0.002
L03.0 Cellulitis of finger and toe	0.000	0.998	0.002
N81.1 Cystocele	0.002	0.998	0.000
Q54.0 Hypospadias, balanic	0.002	0.998	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
Z58.9 Problem related to physical environment, unspecified	0.002	0.998	0.000
Z58.8 Other problems related to physical environment	0.002	0.998	0.000
Z58.7 Exposure to tobacco smoke	0.002	0.998	0.000
Z58.6 Inadequate drinking-water supply	0.002	0.998	0.000
Z58.5 Exposure to other pollution	0.002	0.998	0.000
Z58.4 Exposure to radiation	0.002	0.998	0.000
Z58.3 Exposure to soil pollution	0.002	0.998	0.000
Z58.2 Exposure to water pollution	0.002	0.998	0.000
Z58.0 Exposure to noise	0.002	0.998	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.002	0.998	0.000
Z56.6 Other physical and mental strain related to work	0.002	0.998	0.000
Z56.3 Stressful work schedule	0.002	0.998	0.000
N02 Recurrent and persistent haematuria	0.000	0.998	0.002
K07.3 Anomalies of tooth position	0.002	0.998	0.000
K09.8 Other cysts of oral region, not elsewhere classified	0.002	0.998	0.000
N02.9 Unspecified	0.000	0.998	0.002
N03.8 Other	0.000	0.998	0.002
N03.7 Diffuse crescentic glomerulonephritis	0.000	0.998	0.002
N03.6 Dense deposit disease	0.000	0.998	0.002
N03.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.998	0.002
N03.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.998	0.002
N03.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.998	0.002
N03.2 Diffuse membranous glomerulonephritis	0.000	0.998	0.002
N03.1 Focal and segmental glomerular lesions	0.000	0.998	0.002
N03.0 Minor glomerular abnormality	0.000	0.998	0.002
Z61.9 Negative life events in childhood, unspecified	0.002	0.998	0.000
Z61.8 Other negative life events in childhood	0.002	0.998	0.000
Z61.7 Personal frightening experience in childhood	0.002	0.998	0.000
Z61.6 Problems related to alleged physical abuse of child	0.002	0.998	0.000
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.002	0.998	0.000
Z61.3 Events resulting in loss of self-esteem in childhood	0.002	0.998	0.000
Z61.2 Altered pattern of family relationships in childhood	0.002	0.998	0.000
Z61.1 Removal from home in childhood	0.002	0.998	0.000
Z61.0 Loss of love relationship in childhood	0.002	0.998	0.000
N02.8 Other	0.000	0.998	0.002
Z12.0 Special screening examination for neoplasm of stomach	0.002	0.998	0.000
Z63.6 Dependent relative needing care at home	0.002	0.998	0.000
Z74 Problems related to care-provider dependency	0.002	0.998	0.000
N83.2 Other and unspecified ovarian cysts	0.002	0.998	0.000
Z59.8 Other problems relating to housing and economic circumstances	0.002	0.998	0.000
K07.2 Anomalies of dental arch relationship	0.002	0.998	0.000
Q21.1 Atrial septal defect	0.002	0.998	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.000	0.998	0.002
Z56.7 Other and unspecified problems related to employment	0.002	0.998	0.000
Z56.5 Uncongenial work	0.002	0.998	0.000
Z56.4 Discord with boss and workmates	0.002	0.998	0.000
Z56.2 Threat of job loss	0.002	0.998	0.000
Z56.1 Change of job	0.002	0.998	0.000
Y44 Agents primarily affecting blood constituents	0.002	0.998	0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified	0.002	0.998	0.000
Z73.8 Other problems related to life-management difficulty	0.002	0.998	0.000
Z73.5 Social role conflict, not elsewhere classified	0.002	0.998	0.000
Z73.4 Inadequate social skills, not elsewhere classified	0.002	0.998	0.000
Z73.2 Lack of relaxation and leisure	0.002	0.998	0.000
Z73.1 Accentuation of personality traits	0.002	0.998	0.000
Z73.0 Burn-out	0.002	0.998	0.000
H40.0 Glaucoma suspect	0.000	0.998	0.002
Z45.8 Adjustment and management of other implanted devices	0.001	0.998	0.001
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.002	0.998	0.000
Z59.7 Insufficient social insurance and welfare support	0.002	0.998	0.000
Z59.6 Low income	0.002	0.998	0.000
Z59.5 Extreme poverty	0.002	0.998	0.000
Z59.4 Lack of adequate food	0.002	0.998	0.000
Z59.3 Problems related to living in residential institution	0.002	0.998	0.000
Z59.2 Discord with neighbours, lodgers and landlord	0.002	0.998	0.000
Z59.1 Inadequate housing	0.002	0.998	0.000
Z59.0 Homelessness	0.002	0.998	0.000
H35.3 Degeneration of macula and posterior pole	0.002	0.998	0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.002	0.998	0.000
N83.7 Haematoma of broad ligament	0.002	0.998	0.000
N83.6 Haematosalpinx	0.002	0.998	0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube	0.002	0.998	0.000
Z63.5 Disruption of family by separation and divorce	0.002	0.998	0.000
Q54 Hypospadias	0.002	0.998	0.000
L03.8 Cellulitis of other sites	0.000	0.998	0.002
N83.3 Acquired atrophy of ovary and Fallopian tube	0.002	0.998	0.000
Z56.0 Unemployment, unspecified	0.002	0.998	0.000
K07.6 Temporomandibular joint disorders	0.002	0.998	0.000
Z55.9 Problems relating to education and literacy, unspecified	0.002	0.998	0.000
Z55.8 Other problems relating to education and literacy	0.002	0.998	0.000
Z55.4 Educational maladjustment and discord with teachers and classmates	0.002	0.998	0.000
Z55.3 Underachievement in school	0.002	0.998	0.000
Z55.2 Failed examinations	0.002	0.998	0.000
Z55.1 Schooling unavailable and unattainable	0.002	0.998	0.000
Z55.0 Illiteracy and low-level literacy	0.002	0.998	0.000
Z62.9 Problem related to upbringing, unspecified	0.002	0.998	0.000
Z62.8 Other specified problems related to upbringing	0.002	0.998	0.000
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.002	0.998	0.000
Z62.5 Other problems related to neglect in upbringing	0.002	0.998	0.000
Z62.4 Emotional neglect of child	0.002	0.998	0.000
Z62.3 Hostility towards and scapegoating of child	0.002	0.998	0.000
Z62.2 Institutional upbringing	0.002	0.998	0.000
Z62.1 Parental overprotection	0.002	0.998	0.000
Z62.0 Inadequate parental supervision and control	0.002	0.998	0.000
Z63.9 Problem related to primary support group, unspecified	0.002	0.998	0.000
Z63.3 Absence of family member	0.002	0.998	0.000
Z63.2 Inadequate family support	0.002	0.998	0.000
Z63.1 Problems in relationship with parents and in-laws	0.002	0.998	0.000
Z65.9 Problem related to unspecified psychosocial circumstances	0.002	0.998	0.000
Z65.8 Other specified problems related to psychosocial circumstances	0.002	0.998	0.000
Z65.5 Exposure to disaster, war and other hostilities	0.002	0.998	0.000
Z65.4 Victim of crime and terrorism	0.002	0.998	0.000
Z65.3 Problems related to other legal circumstances	0.002	0.998	0.000
Z65.2 Problems related to release from prison	0.002	0.998	0.000
Z65.1 Imprisonment and other incarceration	0.002	0.998	0.000
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.002	0.998	0.000
K07.9 Dentofacial anomaly, unspecified	0.002	0.998	0.000
K07.8 Other dentofacial anomalies	0.002	0.998	0.000
K07.5 Dentofacial functional abnormalities	0.002	0.998	0.000
K07.0 Major anomalies of jaw size	0.002	0.998	0.000
K10.2 Inflammatory conditions of jaws	0.002	0.998	0.000
Z12.5 Special screening examination for neoplasm of prostate	0.002	0.998	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube	0.002	0.998	0.000
N92.6 Irregular menstruation, unspecified	0.002	0.998	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
Z63.0 Problems in relationship with spouse or partner	0.002	0.998	0.000
T23 Burn and corrosion of wrist and hand	0.002	0.998	0.000
N00-N08 Glomerular diseases	0.000	0.998	0.002
C77.9 Lymph node, unspecified	0.000	0.998	0.002
Q54.9 Hypospadias, unspecified	0.002	0.998	0.000
Z63.4 Disappearance and death of family member	0.002	0.998	0.000
Z64.4 Discord with counsellors	0.001	0.998	0.000
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.001	0.998	0.000
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.001	0.998	0.000
Z64.1 Problems related to multiparity	0.001	0.998	0.000
K10 Other diseases of jaws	0.002	0.998	0.000
K00 Disorders of tooth development and eruption	0.002	0.998	0.000
C67.6 Ureteric orifice	0.002	0.998	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
N02.7 Diffuse crescentic glomerulonephritis	0.000	0.998	0.001
N02.6 Dense deposit disease	0.000	0.998	0.001
N02.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.998	0.001
N02.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.998	0.001
N02.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.998	0.001
N02.2 Diffuse membranous glomerulonephritis	0.000	0.998	0.001
N02.1 Focal and segmental glomerular lesions	0.000	0.998	0.001
N02.0 Minor glomerular abnormality	0.000	0.998	0.001
Z63.8 Other specified problems related to primary support group	0.001	0.998	0.000
Z63.7 Other stressful life events affecting family and household	0.001	0.998	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.002	0.998	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
Z74.9 Problem related to care-provider dependency, unspecified	0.001	0.998	0.000
Z74.3 Need for continuous supervision	0.001	0.998	0.000
Z74.1 Need for assistance with personal care	0.001	0.998	0.000
T23.3 Burn of third degree of wrist and hand	0.002	0.998	0.000
H04.1 Other disorders of lachrymal gland	0.000	0.998	0.002
T43.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
N05 Unspecified nephritic syndrome	0.000	0.998	0.002
Q21 Congenital malformations of cardiac septa	0.002	0.998	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
H34.8 Other retinal vascular occlusions	0.000	0.998	0.002
K00.0 Anodontia	0.001	0.998	0.000
N05.9 Unspecified	0.000	0.998	0.001
Y44.9 Other and unspecified agents affecting blood constituents	0.001	0.998	0.000
Y44.7 Plasma substitutes	0.001	0.998	0.000
Y44.6 Natural blood and blood products	0.001	0.998	0.000
Y44.5 Thrombolytic drugs	0.001	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.001	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.001	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.001	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.001	0.998	0.000
Z64.0 Problems related to unwanted pregnancy	0.001	0.998	0.000
Z74.8 Other problems related to care-provider dependency	0.001	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.001	0.998	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.001	0.998	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.001	0.998	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.002	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.001	0.998	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.001	0.998	0.000
M24.1 Other articular cartilage disorders	0.002	0.998	0.000
Q54.8 Other hypospadias	0.001	0.998	0.000
Q54.4 Congenital chordee	0.001	0.998	0.000
Q54.3 Hypospadias, perineal	0.001	0.998	0.000
Q54.2 Hypospadias, penoscrotal	0.001	0.998	0.000
Q54.1 Hypospadias, penile	0.001	0.998	0.000
Z73.3 Stress, not elsewhere classified	0.001	0.998	0.000
Z74.2 Need for assistance at home and no other household member able to render care	0.001	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.002	0.998	0.000
Y57.8 Other drugs and medicaments	0.001	0.998	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.001	0.998	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.001	0.998	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.001	0.998	0.000
K09.9 Cyst of oral region, unspecified	0.001	0.998	0.000
K10.0 Developmental disorders of jaws	0.001	0.998	0.000
T43.9 Psychotropic drug, unspecified	0.001	0.998	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.001	0.998	0.000
T43.6 Psychostimulants with abuse potential	0.001	0.998	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.001	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.001	0.998	0.000
Z60 Problems related to social environment	0.001	0.998	0.000
Q50-Q56 Congenital malformations of genital organs	0.001	0.998	0.000
L03.3 Cellulitis of trunk	0.000	0.998	0.001
T23.7 Corrosion of third degree of wrist and hand	0.001	0.998	0.000
T23.6 Corrosion of second degree of wrist and hand	0.001	0.998	0.000
T23.5 Corrosion of first degree of wrist and hand	0.001	0.998	0.000
T23.4 Corrosion of unspecified degree of wrist and hand	0.001	0.998	0.000
T23.1 Burn of first degree of wrist and hand	0.001	0.998	0.000
Y42.9 Other and unspecified hormone antagonists	0.001	0.998	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.001	0.998	0.000
Y42.4 Oral contraceptives	0.001	0.998	0.000
Y42.2 Antithyroid drugs	0.001	0.998	0.000
Y42.1 Thyroid hormones and substitutes	0.001	0.998	0.000
Y57.5 X-ray contrast media	0.001	0.998	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.000	0.998	0.001
N06 Isolated proteinuria with specified morphological lesion	0.000	0.998	0.001
N04 Nephrotic syndrome	0.000	0.998	0.001
N01 Rapidly progressive nephritic syndrome	0.000	0.998	0.001
N00 Acute nephritic syndrome	0.000	0.998	0.001
M24.11 Other articular cartilage disorders (Shoulder region)	0.001	0.999	0.000
K00.9 Disorder of tooth development, unspecified	0.001	0.999	0.000
K00.8 Other disorders of tooth development	0.001	0.999	0.000
K00.7 Teething syndrome	0.001	0.999	0.000
K00.5 Hereditary disturbances in tooth structure, not elsewhere classified	0.001	0.999	0.000
K00.4 Disturbances in tooth formation	0.001	0.999	0.000
K00.3 Mottled teeth	0.001	0.999	0.000
K00.2 Abnormalities of size and form of teeth	0.001	0.999	0.000
K00.1 Supernumerary teeth	0.001	0.999	0.000
K10.9 Disease of jaws, unspecified	0.001	0.999	0.000
K10.3 Alveolitis of jaws	0.001	0.999	0.000
K10.1 Giant cell granuloma, central	0.001	0.999	0.000
Q85.9 Phakomatosis, unspecified	0.001	0.999	0.000
Y59 Other and unspecified vaccines and biological substances	0.001	0.999	0.000
Y58 Bacterial vaccines	0.001	0.999	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.001	0.999	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.001	0.999	0.000
Y48 Anaesthetics and therapeutic gases	0.001	0.999	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.001	0.999	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.001	0.999	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.001	0.999	0.000
M46 Other inflammatory spondylopathies	0.001	0.999	0.000
K65.8 Other peritonitis	0.001	0.999	0.000
Z51.8 Other specified medical care	0.001	0.999	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.000	0.999	0.001
Q18.0 Sinus, fistula and cyst of branchial cleft	0.001	0.999	0.000
Y49.9 Psychotropic drug, unspecified	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations