TreeWAS – Variant ID: rs3025387

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K70 Alcoholic liver disease	0.000	0.337	0.663
K70-K77 Diseases of liver	0.000	0.345	0.655
K74 Fibrosis and cirrhosis of liver	0.000	0.356	0.644
K74.6 Other and unspecified cirrhosis of liver	0.000	0.356	0.644
K70.4 Alcoholic hepatic failure	0.000	0.359	0.641
K75 Other inflammatory liver diseases	0.000	0.362	0.638
K70.3 Alcoholic cirrhosis of liver	0.000	0.366	0.634
K75.4 Autoimmune hepatitis	0.000	0.404	0.596
K72 Hepatic failure, not elsewhere classified	0.000	0.426	0.574
K75.0 Abscess of liver	0.000	0.430	0.570
K70.9 Alcoholic liver disease, unspecified	0.000	0.445	0.555
K70.0 Alcoholic fatty liver	0.000	0.447	0.553
K70.1 Alcoholic hepatitis	0.000	0.449	0.551
K72.9 Hepatic failure, unspecified	0.000	0.483	0.517
K75.8 Other specified inflammatory liver diseases	0.000	0.505	0.495
K74.5 Biliary cirrhosis, unspecified	0.000	0.517	0.483
K77 Liver disorders in diseases classified elsewhere	0.000	0.531	0.469
K75.9 Inflammatory liver disease, unspecified	0.000	0.536	0.464
K74.4 Secondary biliary cirrhosis	0.000	0.538	0.462
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.538	0.462
K74.1 Hepatic sclerosis	0.000	0.538	0.462
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.542	0.457
K75.2 Nonspecific reactive hepatitis	0.000	0.542	0.457
K75.1 Phlebitis of portal vein	0.000	0.542	0.457
K73 Chronic hepatitis, not elsewhere classified	0.000	0.549	0.451
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.567	0.432
K74.3 Primary biliary cirrhosis	0.000	0.574	0.426
K72.1 Chronic hepatic failure	0.000	0.588	0.411
K72.0 Acute and subacute hepatic failure	0.000	0.592	0.408
K71 Toxic liver disease	0.000	0.634	0.366
K73.9 Chronic hepatitis, unspecified	0.000	0.652	0.348
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.663	0.337
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.663	0.337
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.677	0.323
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.677	0.323
K74.0 Hepatic fibrosis	0.000	0.694	0.306
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.694	0.306
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.709	0.290
K71.9 Toxic liver disease, unspecified	0.000	0.737	0.262
K71.8 Toxic liver disease with other disorders of liver	0.000	0.737	0.262
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.737	0.262
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.737	0.262
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.737	0.262
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.737	0.262
K71.2 Toxic liver disease with acute hepatitis	0.000	0.737	0.262
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.737	0.262
K71.0 Toxic liver disease with cholestasis	0.001	0.768	0.231
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.001	0.792	0.207
K76 Other diseases of liver	0.000	0.827	0.173
K76.9 Liver disease, unspecified	0.000	0.865	0.135
K76.5 Hepatic veno-occlusive disease	0.000	0.876	0.124
K76.4 Peliosis hepatis	0.000	0.876	0.124
K76.3 Infarction of liver	0.000	0.876	0.124
K76.2 Central haemorrhagic necrosis of liver	0.000	0.876	0.124
K76.1 Chronic passive congestion of liver	0.000	0.876	0.124
K76.7 Hepatorenal syndrome	0.000	0.877	0.123
K76.8 Other specified diseases of liver	0.000	0.919	0.081
K76.6 Portal hypertension	0.000	0.920	0.080
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.949	0.051
E86 Volume depletion	0.000	0.971	0.029
R73.9 Hyperglycaemia, unspecified	0.000	0.977	0.023
S46 Injury of muscle and tendon at shoulder and upper arm level	0.012	0.988	0.000
S40-S49 Injuries to the shoulder and upper arm	0.011	0.989	0.000
S42.10 Fracture of scapula (closed)	0.011	0.989	0.000
R73 Elevated blood glucose level	0.000	0.989	0.011
S42 Fracture of shoulder and upper arm	0.011	0.989	0.000
S42.1 Fracture of scapula	0.010	0.990	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.010	0.990	0.000
S42.4 Fracture of lower end of humerus	0.010	0.990	0.000
S42.40 Fracture of lower end of humerus (closed)	0.010	0.990	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.010	0.990	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.010	0.990	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.010	0.990	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.010	0.990	0.000
M81.98 Osteoporosis, unspecified (Other)	0.000	0.990	0.010
S46.0 Injury of tendon of the rotator cuff of shoulder	0.010	0.990	0.000
S43.1 Dislocation of acromioclavicular joint	0.009	0.991	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.009	0.991	0.000
G44.2 Tension-type headache	0.009	0.991	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.009	0.991	0.000
S46.3 Injury of muscle and tendon of triceps	0.009	0.991	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.008	0.991	0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.008	0.991	0.000
O72.1 Other immediate postpartum haemorrhage	0.000	0.992	0.008
S42.7 Multiple fractures of clavicle, scapula and humerus	0.008	0.992	0.000
S48 Traumatic amputation of shoulder and upper arm	0.008	0.992	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.008	0.992	0.000
S44 Injury of nerves at shoulder and upper arm level	0.008	0.992	0.000
S47 Crushing injury of shoulder and upper arm	0.008	0.992	0.000
S42.41 Fracture of lower end of humerus (open)	0.008	0.992	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.008	0.992	0.000
S42.11 Fracture of scapula (open)	0.008	0.992	0.000
S49.8 Other specified injuries of shoulder and upper arm	0.008	0.992	0.000
S49.7 Multiple injuries of shoulder and upper arm	0.008	0.992	0.000
S41 Open wound of shoulder and upper arm	0.008	0.992	0.000
S43.4 Sprain and strain of shoulder joint	0.008	0.992	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.007	0.992	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.007	0.992	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.007	0.992	0.000
S43.2 Dislocation of sternoclavicular joint	0.007	0.992	0.000
M81.9 Osteoporosis, unspecified	0.000	0.992	0.008
S42.3 Fracture of shaft of humerus	0.007	0.993	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.993	0.007
K29.1 Other acute gastritis	0.000	0.993	0.007
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.007	0.993	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.007	0.993	0.000
S43.0 Dislocation of shoulder joint	0.007	0.993	0.000
H26.9 Cataract, unspecified	0.000	0.993	0.007
S40 Superficial injury of shoulder and upper arm	0.007	0.993	0.000
R73.0 Abnormal glucose tolerance test	0.000	0.993	0.007
S42.31 Fracture of shaft of humerus (open)	0.006	0.994	0.000
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.006	0.994	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.994	0.006
L89.1 Stage II decubitus ulcer	0.000	0.994	0.006
S44.9 Injury of unspecified nerve at shoulder and upper arm level	0.006	0.994	0.000
S44.8 Injury of other nerves at shoulder and upper arm level	0.006	0.994	0.000
S44.7 Injury of multiple nerves at shoulder and upper arm level	0.006	0.994	0.000
S44.5 Injury of cutaneous sensory nerve at shoulder and upper arm level	0.006	0.994	0.000
S44.4 Injury of musculocutaneous nerve	0.006	0.994	0.000
S44.3 Injury of axillary nerve	0.006	0.994	0.000
S44.2 Injury of radial nerve at upper arm level	0.006	0.994	0.000
S44.1 Injury of median nerve at upper arm level	0.006	0.994	0.000
S44.0 Injury of ulnar nerve at upper arm level	0.006	0.994	0.000
S45.9 Injury of unspecified blood vessel at shoulder and upper arm level	0.006	0.994	0.000
S45.8 Injury of other blood vessels at shoulder and upper arm level	0.006	0.994	0.000
S45.7 Injury of multiple blood vessels at shoulder and upper arm level	0.006	0.994	0.000
S45.3 Injury of superficial vein at shoulder and upper arm level	0.006	0.994	0.000
S45.2 Injury of axillary or brachial vein	0.006	0.994	0.000
S45.1 Injury of brachial artery	0.006	0.994	0.000
S45.0 Injury of axillary artery	0.006	0.994	0.000
S48.9 Traumatic amputation of shoulder and upper arm, level unspecified	0.006	0.994	0.000
S48.1 Traumatic amputation at level between shoulder and elbow	0.006	0.994	0.000
S48.0 Traumatic amputation at shoulder joint	0.006	0.994	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.994	0.006
S42.0 Fracture of clavicle	0.006	0.994	0.000
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.006	0.994	0.000
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.006	0.994	0.000
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.006	0.994	0.000
S41.7 Multiple open wounds of shoulder and upper arm	0.006	0.994	0.000
G44 Other headache syndromes	0.006	0.994	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.994	0.006
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.994	0.006
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.994	0.006
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.994	0.006
S41.1 Open wound of upper arm	0.006	0.994	0.000
S41.0 Open wound of shoulder	0.005	0.994	0.000
F20.0 Paranoid schizophrenia	0.005	0.994	0.000
S40.8 Other superficial injuries of shoulder and upper arm	0.005	0.995	0.000
F20.9 Schizophrenia, unspecified	0.005	0.995	0.000
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.005	0.995	0.000
S42.2 Fracture of upper end of humerus	0.005	0.995	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.995	0.005
G44.8 Other specified headache syndromes	0.005	0.995	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.005	0.995	0.000
F20 Schizophrenia	0.005	0.995	0.000
G44.3 Chronic posttraumatic headache	0.005	0.995	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.995	0.005
J32.0 Chronic maxillary sinusitis	0.005	0.995	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.005	0.995	0.000
S42.01 Fracture of clavicle (open)	0.004	0.995	0.000
G44.1 Vascular headache, not elsewhere classified	0.004	0.996	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.004	0.996	0.000
G44.0 Cluster headache syndrome	0.004	0.996	0.000
M54.12 Radiculopathy (Cervical region)	0.004	0.996	0.000
G44.4 Drug-induced headache, not elsewhere classified	0.004	0.996	0.000
N48.4 Impotence of organic origin	0.004	0.996	0.000
M25.76 Osteophyte (Lower leg)	0.004	0.996	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.004	0.996	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.000	0.996	0.004
E11.4 With neurological complications	0.000	0.996	0.004
R77 Other abnormalities of plasma proteins	0.000	0.996	0.004
R77.8 Other specified abnormalities of plasma proteins	0.000	0.996	0.004
S42.21 Fracture of upper end of humerus (open)	0.004	0.996	0.000
E87.0 Hyperosmolality and hypernatraemia	0.000	0.996	0.004
M25.7 Osteophyte	0.004	0.996	0.000
S40.0 Contusion of shoulder and upper arm	0.004	0.996	0.000
F20.8 Other schizophrenia	0.004	0.996	0.000
F20.6 Simple schizophrenia	0.004	0.996	0.000
F20.5 Residual schizophrenia	0.004	0.996	0.000
F20.4 Postschizophrenic depression	0.004	0.996	0.000
F20.3 Undifferentiated schizophrenia	0.004	0.996	0.000
F20.2 Catatonic schizophrenia	0.004	0.996	0.000
F20.1 Hebephrenic schizophrenia	0.004	0.996	0.000
M25.74 Osteophyte (Hand)	0.004	0.996	0.000
M25.71 Osteophyte (Shoulder region)	0.004	0.996	0.000
U80.1 Methicillin resistant agent	0.000	0.996	0.004
M75.5 Bursitis of shoulder	0.000	0.996	0.004
A41.0 Septicaemia due to Staphylococcus aureus	0.000	0.996	0.004
M54.1 Radiculopathy	0.004	0.996	0.000
G63.2 Diabetic polyneuropathy	0.000	0.996	0.004
C15.9 Oesophagus, unspecified	0.000	0.996	0.004
B07 Viral warts	0.004	0.996	0.000
B91 Sequelae of poliomyelitis	0.004	0.996	0.000
C15.5 Lower third of oesophagus	0.000	0.996	0.004
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.000	0.996	0.003
R74 Abnormal serum enzyme levels	0.000	0.997	0.003
M25.73 Osteophyte (Forearm)	0.003	0.997	0.000
S42.30 Fracture of shaft of humerus (closed)	0.003	0.997	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.000	0.997	0.003
M54.17 Radiculopathy (Lumbosacral region)	0.003	0.997	0.000
A41 Other septicaemia	0.000	0.997	0.003
R72 Abnormality of white blood cells, not elsewhere classified	0.000	0.997	0.003
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.003	0.997	0.000
R70.0 Elevated erythrocyte sedimentation rate	0.000	0.997	0.003
E05.9 Thyrotoxicosis, unspecified	0.003	0.997	0.000
R77.9 Abnormality of plasma protein, unspecified	0.000	0.997	0.003
L89 Decubitus ulcer	0.000	0.997	0.003
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.000	0.997	0.003
M25.79 Osteophyte (Site unspecified)	0.003	0.997	0.000
O41.0 Oligohydramnios	0.000	0.997	0.003
R74.8 Abnormal levels of other serum enzymes	0.000	0.997	0.003
M81 Osteoporosis without pathological fracture	0.000	0.997	0.003
R78 Findings of drugs and other substances, not normally found in blood	0.000	0.997	0.003
R77.2 Abnormality of alphafetoprotein	0.000	0.997	0.003
R77.1 Abnormality of globulin	0.000	0.997	0.003
R77.0 Abnormality of albumin	0.000	0.997	0.003
M25.70 Osteophyte (Multiple sites)	0.003	0.997	0.000
M54.19 Radiculopathy (Site unspecified)	0.003	0.997	0.000
A41.9 Septicaemia, unspecified	0.000	0.997	0.003
M25.78 Osteophyte (Other)	0.003	0.997	0.000
L89.2 Stage III decubitus ulcer	0.000	0.997	0.003
H95.1 Other disorders following mastoidectomy	0.003	0.997	0.000
M54.16 Radiculopathy (Lumbar region)	0.003	0.997	0.000
Z02.8 Other examinations for administrative purposes	0.003	0.997	0.000
A41.2 Septicaemia due to unspecified staphylococcus	0.000	0.997	0.003
C15 Malignant neoplasm of oesophagus	0.000	0.997	0.003
M54.15 Radiculopathy (Thoracolumbar region)	0.003	0.997	0.000
M54.14 Radiculopathy (Thoracic region)	0.003	0.997	0.000
M54.13 Radiculopathy (Cervicothoracic region)	0.003	0.997	0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.003	0.997	0.000
M54.10 Radiculopathy (Multiple sites in spine)	0.003	0.997	0.000
L89.3 Stage IV decubitus ulcer	0.000	0.997	0.003
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.997	0.003
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]	0.000	0.997	0.003
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.003	0.997	0.000
S42.00 Fracture of clavicle (closed)	0.003	0.997	0.000
L03.3 Cellulitis of trunk	0.000	0.997	0.003
E87.2 Acidosis	0.000	0.997	0.003
S02.60 Fracture of mandible (closed)	0.003	0.997	0.000
A41.4 Septicaemia due to anaerobes	0.000	0.997	0.003
A41.3 Septicaemia due to Haemophilus influenzae	0.000	0.997	0.003
N48.6 Balanitis xerotica obliterans	0.003	0.997	0.000
F23 Acute and transient psychotic disorders	0.003	0.997	0.000
M25.72 Osteophyte (Upper arm)	0.003	0.997	0.000
R71 Abnormality of red blood cells	0.000	0.997	0.002
F23.9 Acute and transient psychotic disorder, unspecified	0.003	0.997	0.000
Z92.4 Personal history of major surgery, not elsewhere classified	0.003	0.997	0.000
G43.8 Other migraine	0.003	0.997	0.000
W10.8 Other specified place	0.003	0.997	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.000	0.997	0.003
S02.80 Fractures of other skull and facial bones (closed)	0.003	0.997	0.000
R70.1 Abnormal plasma viscosity	0.000	0.997	0.002
B00 Herpesviral [herpes simplex] infections	0.003	0.997	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.003	0.997	0.000
M81.8 Other osteoporosis	0.000	0.997	0.002
M81.6 Localised osteoporosis [Lequesne]	0.000	0.997	0.002
M81.5 Idiopathic osteoporosis	0.000	0.997	0.002
M81.1 Postoophorectomy osteoporosis	0.000	0.997	0.002
U80 Agent resistant to penicillin and related antibiotics	0.000	0.997	0.003
R78.9 Finding of unspecified substance, not normally found in blood	0.000	0.997	0.002
R78.8 Finding of other specified substances, not normally found in blood	0.000	0.997	0.002
R78.7 Finding of abnormal level of heavy metals in blood	0.000	0.997	0.002
R78.6 Finding of steroid agent in blood	0.000	0.997	0.002
R78.5 Finding of psychotropic drug in blood	0.000	0.997	0.002
R78.4 Finding of other drugs of addictive potential in blood	0.000	0.997	0.002
R78.3 Finding of hallucinogen in blood	0.000	0.997	0.002
R78.2 Finding of cocaine in blood	0.000	0.997	0.002
R78.1 Finding of opiate drug in blood	0.000	0.997	0.002
M81.2 Osteoporosis of disuse	0.000	0.997	0.002
F22 Persistent delusional disorders	0.002	0.997	0.000
B00.4 Herpesviral encephalitis	0.002	0.997	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.000	0.997	0.002
O26.8 Other specified pregnancy-related conditions	0.000	0.997	0.003
R78.0 Finding of alcohol in blood	0.000	0.997	0.002
R74.9 Abnormal level of unspecified serum enzyme	0.000	0.998	0.002
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.002	0.998	0.000
O72 Postpartum haemorrhage	0.000	0.998	0.002
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.998	0.002
M81.0 Postmenopausal osteoporosis	0.000	0.998	0.002
A41.1 Septicaemia due to other specified staphylococcus	0.000	0.998	0.002
F25 Schizoaffective disorders	0.002	0.998	0.000
F22.0 Delusional disorder	0.002	0.998	0.000
M81.4 Drug-induced osteoporosis	0.000	0.998	0.002
B90-B94 Sequelae of infectious and parasitic diseases	0.002	0.998	0.000
C15.8 Overlapping lesion of oesophagus	0.000	0.998	0.002
C15.4 Middle third of oesophagus	0.000	0.998	0.002
C15.2 Abdominal part of oesophagus	0.000	0.998	0.002
C15.1 Thoracic part of oesophagus	0.000	0.998	0.002
C15.0 Cervical part of oesophagus	0.000	0.998	0.002
R76 Other abnormal immunological findings in serum	0.000	0.998	0.002
B00.1 Herpesviral vesicular dermatitis	0.002	0.998	0.000
H26.4 After-cataract	0.000	0.998	0.002
U80.0 Penicillin resistant agent	0.000	0.998	0.002
A41.8 Other specified septicaemia	0.000	0.998	0.002
G58.8 Other specified mononeuropathies	0.002	0.998	0.000
H60.1 Cellulitis of external ear	0.000	0.998	0.002
F28 Other nonorganic psychotic disorders	0.002	0.998	0.000
F24 Induced delusional disorder	0.002	0.998	0.000
F21 Schizotypal disorder	0.002	0.998	0.000
S02.6 Fracture of mandible	0.002	0.998	0.000
B49 Unspecified mycosis	0.002	0.998	0.000
C15.3 Upper third of oesophagus	0.000	0.998	0.002
S22.20 Fracture of sternum (closed)	0.002	0.998	0.000
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis	0.002	0.998	0.000
F23.8 Other acute and transient psychotic disorders	0.002	0.998	0.000
F23.3 Other acute predominantly delusional psychotic disorders	0.002	0.998	0.000
F23.2 Acute schizophrenia-like psychotic disorder	0.002	0.998	0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.002	0.998	0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.002	0.998	0.000
S02.8 Fractures of other skull and facial bones	0.002	0.998	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.000	0.998	0.002
G63.6 Polyneuropathy in other musculoskeletal disorders	0.000	0.998	0.002
G63.5 Polyneuropathy in systemic connective tissue disorders	0.000	0.998	0.002
G63.4 Polyneuropathy in nutritional deficiency	0.000	0.998	0.002
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.000	0.998	0.002
G63.1 Polyneuropathy in neoplastic disease	0.000	0.998	0.002
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
B24 Unspecified human immunodeficiency virus [HIV] disease	0.002	0.998	0.000
B00.8 Other forms of herpesviral infection	0.002	0.998	0.000
B00.7 Disseminated herpesviral disease	0.002	0.998	0.000
B00.3 Herpesviral meningitis	0.002	0.998	0.000
B00.0 Eczema herpeticum	0.002	0.998	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.002	0.998	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.000	0.998	0.002
M81.18 Postoophorectomy osteoporosis (Other)	0.000	0.998	0.002
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.000	0.998	0.002
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.14 Postoophorectomy osteoporosis (Hand)	0.000	0.998	0.002
M81.13 Postoophorectomy osteoporosis (Forearm)	0.000	0.998	0.002
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.000	0.998	0.002
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.000	0.998	0.002
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.000	0.998	0.002
M81.59 Idiopathic osteoporosis (Site unspecified)	0.000	0.998	0.002
M81.58 Idiopathic osteoporosis (Other)	0.000	0.998	0.002
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.56 Idiopathic osteoporosis (Lower leg)	0.000	0.998	0.002
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.54 Idiopathic osteoporosis (Hand)	0.000	0.998	0.002
M81.53 Idiopathic osteoporosis (Forearm)	0.000	0.998	0.002
M81.52 Idiopathic osteoporosis (Upper arm)	0.000	0.998	0.002
M81.51 Idiopathic osteoporosis (Shoulder region)	0.000	0.998	0.002
M81.50 Idiopathic osteoporosis (Multiple sites)	0.000	0.998	0.002
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.000	0.998	0.002
M81.68 Localized osteoporosis [Lequesne] (Other)	0.000	0.998	0.002
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.000	0.998	0.002
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.000	0.998	0.002
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.000	0.998	0.002
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.000	0.998	0.002
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.000	0.998	0.002
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.000	0.998	0.002
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.000	0.998	0.002
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.000	0.998	0.002
M81.89 Other osteoporosis (Site unspecified)	0.000	0.998	0.002
M81.88 Other osteoporosis (Other)	0.000	0.998	0.002
M81.87 Other osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.86 Other osteoporosis (Lower leg)	0.000	0.998	0.002
M81.85 Other osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.84 Other osteoporosis (Hand)	0.000	0.998	0.002
M81.83 Other osteoporosis (Forearm)	0.000	0.998	0.002
M81.82 Other osteoporosis (Upper arm)	0.000	0.998	0.002
M81.81 Other osteoporosis (Shoulder region)	0.000	0.998	0.002
M81.80 Other osteoporosis (Multiple sites)	0.000	0.998	0.002
F25.0 Schizoaffective disorder, manic type	0.002	0.998	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.000	0.998	0.002
M81.28 Osteoporosis of disuse (Other)	0.000	0.998	0.002
M81.27 Osteoporosis of disuse (Ankle and foot)	0.000	0.998	0.002
M81.26 Osteoporosis of disuse (Lower leg)	0.000	0.998	0.002
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.000	0.998	0.002
M81.24 Osteoporosis of disuse (Hand)	0.000	0.998	0.002
M81.23 Osteoporosis of disuse (Forearm)	0.000	0.998	0.002
M81.22 Osteoporosis of disuse (Upper arm)	0.000	0.998	0.002
M81.21 Osteoporosis of disuse (Shoulder region)	0.000	0.998	0.002
B00.5 Herpesviral ocular disease	0.002	0.998	0.000
F22.9 Persistent delusional disorder, unspecified	0.002	0.998	0.000
F22.8 Other persistent delusional disorders	0.002	0.998	0.000
B35.3 Tinea pedis	0.002	0.998	0.000
B06 Rubella [German measles]	0.002	0.998	0.000
B05 Measles	0.002	0.998	0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.002	0.998	0.000
B04 Monkeypox	0.002	0.998	0.000
B03 Smallpox	0.002	0.998	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.000	0.998	0.002
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.998	0.002
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.000	0.998	0.002
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.000	0.998	0.002
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.000	0.998	0.002
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.000	0.998	0.002
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.000	0.998	0.002
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.000	0.998	0.002
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.000	0.998	0.002
L89.0 Stage I decubitus ulcer and pressure area	0.000	0.998	0.002
O32.1 Maternal care for breech presentation	0.000	0.998	0.002
O72.3 Postpartum coagulation defects	0.000	0.998	0.002
M81.08 Postmenopausal osteoporosis (Other)	0.000	0.998	0.002
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.06 Postmenopausal osteoporosis (Lower leg)	0.000	0.998	0.002
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.04 Postmenopausal osteoporosis (Hand)	0.000	0.998	0.002
M81.03 Postmenopausal osteoporosis (Forearm)	0.000	0.998	0.002
M81.02 Postmenopausal osteoporosis (Upper arm)	0.000	0.998	0.002
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.000	0.998	0.002
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.000	0.998	0.002
G93.9 Disorder of brain, unspecified	0.002	0.998	0.000
H26 Other cataract	0.000	0.998	0.002
B00.9 Herpesviral infection, unspecified	0.002	0.998	0.000
G62.0 Drug-induced polyneuropathy	0.000	0.998	0.002
M81.48 Drug-induced osteoporosis (Other)	0.000	0.998	0.002
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.46 Drug-induced osteoporosis (Lower leg)	0.000	0.998	0.002
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.44 Drug-induced osteoporosis (Hand)	0.000	0.998	0.002
M81.43 Drug-induced osteoporosis (Forearm)	0.000	0.998	0.002
M81.42 Drug-induced osteoporosis (Upper arm)	0.000	0.998	0.002
M81.41 Drug-induced osteoporosis (Shoulder region)	0.000	0.998	0.002
F25.9 Schizoaffective disorder, unspecified	0.002	0.998	0.000
F25.8 Other schizoaffective disorders	0.002	0.998	0.000
F25.2 Schizoaffective disorder, mixed type	0.002	0.998	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.000	0.998	0.002
E55.9 Vitamin D deficiency, unspecified	0.002	0.998	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.002	0.998	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.000	0.998	0.002
B02 Zoster [herpes zoster]	0.002	0.998	0.000
B90 Sequelae of tuberculosis	0.002	0.998	0.000
B92 Sequelae of leprosy	0.002	0.998	0.000
R76.9 Abnormal immunological finding in serum, unspecified	0.000	0.998	0.002
R76.2 False-positive serological test for syphilis	0.000	0.998	0.002
R76.1 Abnormal reaction to tuberculin test	0.000	0.998	0.002
F25.1 Schizoaffective disorder, depressive type	0.002	0.998	0.000
K65.0 Acute peritonitis	0.000	0.998	0.002
R79 Other abnormal findings of blood chemistry	0.000	0.998	0.002
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.998	0.002
S02.40 Fracture of malar and maxillary bones (closed)	0.002	0.998	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.002	0.998	0.000
J32.4 Chronic pansinusitis	0.000	0.998	0.002
B94 Sequelae of other and unspecified infectious and parasitic diseases	0.002	0.998	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.000	0.998	0.002
B02.3 Zoster ocular disease	0.002	0.998	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.002	0.998	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.998	0.002
B35 Dermatophytosis	0.002	0.998	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.000	0.998	0.002
S02.61 Fracture of mandible (open)	0.002	0.998	0.000
S02.4 Fracture of malar and maxillary bones	0.002	0.998	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.998	0.002
G62 Other polyneuropathies	0.000	0.998	0.002
O26 Maternal care for other conditions predominantly related to pregnancy	0.000	0.998	0.002
B20-B24 Human immunodeficiency virus [HIV] disease	0.002	0.998	0.000
R76.0 Raised antibody titer	0.000	0.998	0.001
S02.81 Fractures of other skull and facial bones (open)	0.002	0.998	0.000
N50.1 Vascular disorders of male genital organs	0.000	0.998	0.002
G43 Migraine	0.002	0.998	0.000
S02 Fracture of skull and facial bones	0.002	0.998	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.000	0.998	0.002
D63.0 Anaemia in neoplastic disease	0.000	0.998	0.002
I27.2 Other secondary pulmonary hypertension	0.002	0.998	0.000
B35.4 Tinea corporis	0.002	0.998	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.998	0.002
E05.8 Other thyrotoxicosis	0.002	0.998	0.000
E05.5 Thyroid crisis or storm	0.002	0.998	0.000
E05.4 Thyrotoxicosis factitia	0.002	0.998	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.002	0.998	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.002	0.998	0.000
H26.0 Infantile, juvenile and presenile cataract	0.000	0.998	0.002
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.002	0.998	0.000
B01 Varicella [chickenpox]	0.002	0.998	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.002	0.998	0.000
A69.9 Spirochaetal infection, unspecified	0.002	0.998	0.000
B20 Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases	0.002	0.998	0.000
B35-B49 Mycoses	0.002	0.998	0.000
B05.9 Measles without complication	0.002	0.998	0.000
B05.8 Measles with other complications	0.002	0.998	0.000
B05.4 Measles with intestinal complications	0.002	0.998	0.000
B05.3 Measles complicated by otitis media	0.002	0.998	0.000
B05.2 Measles complicated by pneumonia	0.002	0.998	0.000
B05.1 Measles complicated by meningitis	0.002	0.998	0.000
B05.0 Measles complicated by encephalitis	0.002	0.998	0.000
B06.9 Rubella without complication	0.002	0.998	0.000
B06.8 Rubella with other complications	0.002	0.998	0.000
B06.0 Rubella with neurological complications	0.002	0.998	0.000
B47.9 Mycetoma, unspecified	0.002	0.998	0.000
B47 Mycetoma	0.002	0.998	0.000
F99 Mental disorder, not otherwise specified	0.000	0.998	0.002
G43.3 Complicated migraine	0.002	0.998	0.000
K07.2 Anomalies of dental arch relationship	0.002	0.998	0.000
O26.9 Pregnancy-related condition, unspecified	0.000	0.998	0.002
Z22.3 Carrier of other specified bacterial diseases	0.000	0.998	0.002
B20.3 HIV disease resulting in other viral infections	0.002	0.998	0.000
G60 Hereditary and idiopathic neuropathy	0.000	0.998	0.002
O41 Other disorders of amniotic fluid and membranes	0.000	0.998	0.002
B02.8 Zoster with other complications	0.002	0.998	0.000
B02.7 Disseminated zoster	0.002	0.998	0.000
B02.1 Zoster meningitis	0.002	0.998	0.000
B02.0 Zoster encephalitis	0.002	0.998	0.000
B90.9 Sequelae of respiratory and unspecified tuberculosis	0.001	0.998	0.000
B90.8 Sequelae of tuberculosis of other organs	0.001	0.998	0.000
B90.2 Sequelae of tuberculosis of bones and joints	0.001	0.998	0.000
B90.1 Sequelae of genito-urinary tuberculosis	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations