TreeWAS – Variant ID: rs3103933

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I35.0 Aortic (valve) stenosis	0.000	0.043	0.957
I35 Nonrheumatic aortic valve disorders	0.000	0.047	0.953
I35.9 Aortic valve disorder, unspecified	0.000	0.057	0.943
I35.8 Other aortic valve disorders	0.000	0.122	0.878
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.167	0.833
I35.1 Aortic (valve) insufficiency	0.000	0.247	0.753
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.520	0.480	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.517	0.483	0.000
T39.1 4-Aminophenol derivatives	0.505	0.495	0.000
T39.0 Salicylates	0.488	0.512	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.478	0.522	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.454	0.546	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.424	0.576	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.418	0.582	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.400	0.600	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.388	0.612	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.380	0.620	0.000
T39.4 Antirheumatics, not elsewhere classified	0.373	0.627	0.000
T39.2 Pyrazolone derivatives	0.373	0.627	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.365	0.635	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.362	0.638	0.000
T36 Poisoning by systemic antibiotics	0.353	0.646	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.350	0.650	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.345	0.655	0.000
T42.1 Iminostilbenes	0.344	0.656	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.343	0.657	0.000
T38.1 Thyroid hormones and substitutes	0.342	0.658	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.335	0.665	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.334	0.666	0.000
T42.0 Hydantoin derivatives	0.333	0.667	0.000
T40.4 Other synthetic narcotics	0.332	0.668	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.329	0.671	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.325	0.674	0.000
T42.2 Succinimides and oxazolidinediones	0.325	0.674	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.321	0.678	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.318	0.682	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.317	0.683	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.314	0.685	0.000
T42.4 Benzodiazepines	0.313	0.687	0.000
T42.3 Barbiturates	0.311	0.689	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.310	0.689	0.000
T40.1 Heroin	0.308	0.692	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.305	0.695	0.000
T38.9 Other and unspecified hormone antagonists	0.300	0.700	0.000
T38.7 Androgens and anabolic congeners	0.300	0.700	0.000
T38.4 Oral contraceptives	0.300	0.700	0.000
T38.2 Antithyroid drugs	0.300	0.700	0.000
T38.0 Glucocorticoids and synthetic analogues	0.297	0.703	0.000
T40.5 Cocaine	0.293	0.707	0.000
T40.6 Other and unspecified narcotics	0.292	0.708	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.291	0.709	0.000
T38.5 Other oestrogens and progestogens	0.290	0.710	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.289	0.711	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.287	0.713	0.000
T40.8 Lysergide [LSD]	0.287	0.713	0.000
T40.7 Cannabis (derivatives)	0.287	0.713	0.000
T40.0 Opium	0.287	0.713	0.000
T40.3 Methadone	0.284	0.716	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.282	0.717	0.000
T43.9 Psychotropic drug, unspecified	0.281	0.719	0.000
T36.0 Penicillins	0.280	0.720	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.278	0.721	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.278	0.722	0.000
T40.2 Other opioids	0.274	0.726	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.265	0.735	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.255	0.744	0.000
T36.9 Systemic antibiotic, unspecified	0.253	0.746	0.000
T36.7 Antifungal antibiotics, systemically used	0.253	0.746	0.000
T36.6 Rifamycins	0.253	0.746	0.000
T36.5 Aminoglycosides	0.253	0.746	0.000
T36.2 Chloramphenicol group	0.253	0.746	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.253	0.746	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.253	0.747	0.000
T36.4 Tetracyclines	0.252	0.748	0.000
T36.8 Other systemic antibiotics	0.251	0.748	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.251	0.749	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.251	0.749	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.251	0.749	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.251	0.749	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.251	0.749	0.000
T44.0 Anticholinesterase agents	0.251	0.749	0.000
T48.5 Anti-common-cold drugs	0.247	0.752	0.000
T41.5 Therapeutic gases	0.246	0.754	0.000
T41.4 Anaesthetic, unspecified	0.246	0.754	0.000
T41.3 Local anaesthetics	0.246	0.754	0.000
T41.2 Other and unspecified general anaesthetics	0.246	0.754	0.000
T41.1 Intravenous anaesthetics	0.246	0.754	0.000
T41.0 Inhaled anaesthetics	0.246	0.754	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.245	0.755	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.244	0.756	0.000
T91 Sequelae of injuries of neck and trunk	0.243	0.757	0.000
T43.6 Psychostimulants with abuse potential	0.242	0.758	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.239	0.760	0.000
T48.4 Expectorants	0.239	0.760	0.000
T48.3 Antitussives	0.239	0.760	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.239	0.760	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.239	0.760	0.000
T48.0 Oxytocic drugs	0.239	0.760	0.000
T36.3 Macrolides	0.237	0.763	0.000
T50.4 Drugs affecting uric acid metabolism	0.237	0.763	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.237	0.763	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.236	0.763	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.236	0.764	0.000
T46.7 Peripheral vasodilators	0.236	0.764	0.000
T91.3 Sequelae of injury of spinal cord	0.236	0.764	0.000
T90 Sequelae of injuries of head	0.235	0.765	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.235	0.765	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.234	0.765	0.000
T92 Sequelae of injuries of upper limb	0.232	0.768	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.232	0.768	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.231	0.769	0.000
T50.7 Analeptics and opioid receptor antagonists	0.231	0.769	0.000
T50.5 Appetite depressants	0.231	0.769	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.231	0.769	0.000
T50.0 Mineralocorticoids and their antagonists	0.231	0.769	0.000
T46.1 Calcium-channel blockers	0.230	0.770	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.230	0.770	0.000
S20-S29 Injuries to the thorax	0.229	0.771	0.000
T50.1 Loop [high-ceiling] diuretics	0.229	0.771	0.000
T49.9 Topical agent, unspecified	0.228	0.772	0.000
T49.8 Other topical agents	0.228	0.772	0.000
T49.7 Dental drugs, topically applied	0.228	0.772	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.228	0.772	0.000
T49.5 Ophthalmological drugs and preparations	0.228	0.772	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.228	0.772	0.000
T49.3 Emollients, demulcents and protectants	0.228	0.772	0.000
T49.2 Local astringents and local detergents	0.228	0.772	0.000
T49.1 Antipruritics	0.228	0.772	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.228	0.772	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.226	0.774	0.000
S22.0 Fracture of thoracic vertebra	0.225	0.775	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.223	0.777	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.223	0.777	0.000
T37.5 Antiviral drugs	0.223	0.777	0.000
T37.4 Anthelminthics	0.223	0.777	0.000
T37.3 Other antiprotozoal drugs	0.223	0.777	0.000
T37.1 Antimycobacterial drugs	0.223	0.777	0.000
T37.0 Sulphonamides	0.223	0.777	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.223	0.777	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.222	0.777	0.001
S22.4 Multiple fractures of ribs	0.222	0.778	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.221	0.778	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.221	0.779	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.221	0.779	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.220	0.780	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.219	0.781	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.218	0.782	0.000
T50.8 Diagnostic agents	0.217	0.782	0.000
S22.40 Multiple fractures of ribs (closed)	0.216	0.784	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.215	0.785	0.000
T47.2 Stimulant laxatives	0.211	0.789	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.209	0.791	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.207	0.793	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.207	0.793	0.000
T47.7 Emetics	0.207	0.793	0.000
T47.5 Digestants	0.207	0.793	0.000
T47.3 Saline and osmotic laxatives	0.207	0.793	0.000
T90.4 Sequelae of injury of eye and orbit	0.207	0.793	0.000
S70-S79 Injuries to the hip and thigh	0.207	0.793	0.000
T43.2 Other and unspecified antidepressants	0.206	0.794	0.000
T91.1 Sequelae of fracture of spine	0.206	0.794	0.000
T90.1 Sequelae of open wound of head	0.205	0.795	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.204	0.796	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.204	0.796	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.203	0.797	0.000
S81.0 Open wound of knee	0.198	0.802	0.000
S36 Injury of intra-abdominal organs	0.193	0.806	0.000
T47.6 Antidiarrhoeal drugs	0.193	0.807	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.192	0.808	0.000
S81 Open wound of lower leg	0.189	0.811	0.000
S72 Fracture of femur	0.189	0.811	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.188	0.812	0.000
T90.3 Sequelae of injury of cranial nerves	0.187	0.813	0.000
S80-S89 Injuries to the knee and lower leg	0.187	0.813	0.000
S72.3 Fracture of shaft of femur	0.186	0.814	0.000
S72.30 Fracture of shaft of femur (closed)	0.186	0.814	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.186	0.814	0.000
T47.4 Other laxatives	0.185	0.815	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.183	0.816	0.000
T45.8 Other primarily systemic and haematological agents	0.183	0.816	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.183	0.816	0.000
T45.6 Fibrinolysis-affecting drugs	0.183	0.816	0.000
T45.4 Iron and its compounds	0.183	0.816	0.000
T45.3 Enzymes, not elsewhere classified	0.183	0.816	0.000
T90.0 Sequelae of superficial injury of head	0.183	0.817	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.181	0.819	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.181	0.819	0.000
T47.0 Histamine H(2)-receptor antagonists	0.180	0.819	0.000
S22.2 Fracture of sternum	0.180	0.820	0.000
S10-S19 Injuries to the neck	0.180	0.820	0.000
T90.9 Sequelae of unspecified injury of head	0.179	0.821	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.179	0.821	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.179	0.821	0.000
S27 Injury of other and unspecified intrathoracic organs	0.178	0.822	0.000
S22.5 Flail chest	0.178	0.822	0.000
S31 Open wound of abdomen, lower back and pelvis	0.177	0.823	0.000
S21 Open wound of thorax	0.176	0.824	0.000
T45.2 Vitamins, not elsewhere classified	0.176	0.824	0.000
T95 Sequelae of burns, corrosions and frostbite	0.175	0.825	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.175	0.825	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.175	0.825	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.175	0.825	0.000
S24 Injury of nerves and spinal cord at thorax level	0.174	0.826	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.172	0.828	0.000
T92.1 Sequelae of fracture of arm	0.172	0.828	0.000
T45.0 Antiallergic and antiemetic drugs	0.171	0.829	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.169	0.831	0.000
S36.1 Injury of liver or gallbladder	0.169	0.831	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.168	0.832	0.000
T33-T35 Frostbite	0.167	0.833	0.000
S22.9 Fracture of bony thorax, part unspecified	0.166	0.834	0.000
S22.8 Fracture of other parts of bony thorax	0.166	0.834	0.000
T90.5 Sequelae of intracranial injury	0.166	0.834	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.165	0.835	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.164	0.835	0.000
S26 Injury of heart	0.164	0.835	0.000
S25 Injury of blood vessels of thorax	0.164	0.835	0.000
S37 Injury of urinary and pelvic organs	0.164	0.836	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.164	0.836	0.000
S72.9 Fracture of femur, part unspecified	0.163	0.837	0.000
S32 Fracture of lumbar spine and pelvis	0.163	0.837	0.000
S22.01 Fracture of thoracic vertebra (open)	0.161	0.839	0.000
T92.0 Sequelae of open wound of upper limb	0.161	0.839	0.000
S22.1 Multiple fractures of thoracic spine	0.160	0.840	0.000
S71 Open wound of hip and thigh	0.160	0.840	0.000
S22.41 Multiple fractures of ribs (open)	0.159	0.841	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.159	0.841	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.158	0.842	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.158	0.842	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.156	0.844	0.000
T79-T79 Certain early complications of trauma	0.154	0.844	0.002
S75 Injury of blood vessels at hip and thigh level	0.156	0.844	0.000
S12 Fracture of neck	0.152	0.848	0.000
S36.10 Injury of liver or gallbladder (without open wound into cavity)	0.151	0.849	0.000
S81.8 Open wound of other parts of lower leg	0.150	0.850	0.000
S70 Superficial injury of hip and thigh	0.150	0.850	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.149	0.851	0.000
S81.7 Multiple open wounds of lower leg	0.148	0.851	0.000
S78 Traumatic amputation of hip and thigh	0.148	0.852	0.000
S77 Crushing injury of hip and thigh	0.148	0.852	0.000
S74 Injury of nerves at hip and thigh level	0.148	0.852	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.148	0.852	0.000
S79 Other and unspecified injuries of hip and thigh	0.147	0.853	0.000
S33.1 Dislocation of lumbar vertebra	0.147	0.853	0.000
T90.8 Sequelae of other specified injuries of head	0.147	0.853	0.000
S31.0 Open wound of lower back and pelvis	0.147	0.853	0.000
T00-T07 Injuries involving multiple body regions	0.146	0.854	0.000
T98 Sequelae of other and unspecified effects of external causes	0.146	0.854	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.146	0.854	0.000
S36.4 Injury of small intestine	0.145	0.855	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.145	0.855	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.145	0.855	0.000
S36.5 Injury of colon	0.144	0.856	0.000
S22.20 Fracture of sternum (closed)	0.144	0.856	0.000
S36.8 Injury of other intra-abdominal organs	0.143	0.857	0.000
T95.1 Sequelae of burn, corrosion and frostbite of trunk	0.141	0.858	0.000
S27.3 Other injuries of lung	0.141	0.859	0.000
S31.4 Open wound of vagina and vulva	0.141	0.859	0.000
S22.50 Flail chest (closed)	0.140	0.860	0.000
S36.9 Injury of unspecified intra-abdominal organ	0.139	0.861	0.000
S36.7 Injury of multiple intra-abdominal organs	0.139	0.861	0.000
S36.6 Injury of rectum	0.139	0.861	0.000
S36.3 Injury of stomach	0.139	0.861	0.000
S36.2 Injury of pancreas	0.139	0.861	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.139	0.861	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.138	0.862	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.138	0.862	0.000
S27.2 Traumatic heamopneumothorax	0.137	0.862	0.000
S72.7 Multiple fractures of femur	0.137	0.863	0.000
S86 Injury of muscle and tendon at lower leg level	0.137	0.863	0.000
S12.1 Fracture of second cervical vertebra	0.137	0.863	0.000
S14 Injury of nerves and spinal cord at neck level	0.137	0.863	0.000
S27.0 Traumatic pneumothorax	0.136	0.864	0.000
T45.5 Anticoagulants	0.136	0.864	0.000
S29 Other and unspecified injuries of thorax	0.136	0.864	0.000
S36.0 Injury of spleen	0.135	0.864	0.000
S84 Injury of nerves at lower leg level	0.135	0.864	0.000
S31.1 Open wound of abdominal wall	0.135	0.865	0.000
S85 Injury of blood vessels at lower leg level	0.135	0.865	0.000
S71.1 Open wound of thigh	0.135	0.865	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.135	0.865	0.000
S19 Other and unspecified injuries of neck	0.135	0.865	0.000
S21.9 Open wound of thorax, part unspecified	0.134	0.865	0.000
S24.1 Other and unspecified injuries of thoracic spinal cord	0.134	0.866	0.000
T95.0 Sequelae of burn, corrosion and frostbite of head and neck	0.134	0.866	0.000
S88 Traumatic amputation of lower leg	0.134	0.866	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.133	0.867	0.000
S21.0 Open wound of breast	0.133	0.867	0.000
S35.2 Injury of coeliac or mesenteric artery	0.132	0.868	0.000
S21.2 Open wound of back wall of thorax	0.132	0.868	0.000
S72.2 Subtrochanteric fracture	0.132	0.868	0.000
S32.3 Fracture of ilium	0.131	0.868	0.000
S87 Crushing injury of lower leg	0.131	0.869	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.131	0.869	0.000
S72.31 Fracture of shaft of femur (open)	0.131	0.869	0.000
S33.2 Dislocation of sacro-iliac and sacrococcygeal joint	0.131	0.869	0.000
S33.5 Sprain and strain of lumbar spine	0.130	0.870	0.000
S22.21 Fracture of sternum (open)	0.129	0.870	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.129	0.871	0.000
S17 Crushing injury of neck	0.129	0.871	0.000
S15 Injury of blood vessels at neck level	0.129	0.871	0.000
S18 Traumatic amputation at neck level	0.129	0.871	0.000
S16 Injury of muscle and tendon at neck level	0.129	0.871	0.000
S33.7 Sprain and strain of other and unspecified parts of lumbar spine and pelvis	0.129	0.871	0.000
S33.6 Sprain and strain of sacro-iliac joint	0.129	0.871	0.000
S33.4 Traumatic rupture of symphysis pubis	0.129	0.871	0.000
S33.3 Dislocation of other and unspecified parts of lumbar spine and pelvis	0.129	0.871	0.000
S33.0 Traumatic rupture of lumbar intervertebral disk	0.129	0.871	0.000
S27.9 Injury of unspecified intrathoracic organ	0.128	0.872	0.000
S27.7 Multiple injuries of intrathoracic organs	0.128	0.872	0.000
S27.6 Injury of pleura	0.128	0.872	0.000
S27.5 Injury of thoracic trachea	0.128	0.872	0.000
S27.4 Injury of bronchus	0.128	0.872	0.000
S22.51 Flail chest (open)	0.128	0.872	0.000
S31.5 Open wound of other and unspecified external genital organs	0.127	0.873	0.000
S21.8 Open wound of other parts of thorax	0.127	0.873	0.000
S21.7 Multiple open wounds of thoracic wall	0.127	0.873	0.000
S31.2 Open wound of penis	0.127	0.873	0.000
S72.8 Fractures of other parts of femur	0.126	0.873	0.000
T95.9 Sequelae of unspecified burn, corrosion and frostbite	0.126	0.874	0.000
T95.4 Sequelae of burn and corrosion classifiable only according to extent of body surface involved	0.126	0.874	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.126	0.874	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.126	0.874	0.000
S24.6 Injury of unspecified nerve of thorax	0.125	0.875	0.000
S24.5 Injury of other nerves of thorax	0.125	0.875	0.000
S24.4 Injury of thoracic sympathetic nerves	0.125	0.875	0.000
S24.3 Injury of peripheral nerves of thorax	0.125	0.875	0.000
S24.2 Injury of nerve root of thoracic spine	0.125	0.875	0.000
S24.0 Concussion and oedema of thoracic spinal cord	0.125	0.875	0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.124	0.876	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.124	0.876	0.000
S31.3 Open wound of scrotum and testes	0.123	0.877	0.000
S37.2 Injury of bladder	0.123	0.877	0.000
T30 Burn and corrosion, body region unspecified	0.122	0.877	0.000
T95.8 Sequelae of other specified burn, corrosion and frostbite	0.122	0.877	0.000
S34.1 Other injury of lumbar spinal cord	0.122	0.878	0.000
S35.9 Injury of unspecified blood vessel at abdomen, lower back and pelvis level	0.122	0.878	0.000
S35.8 Injury of other blood vessels at abdomen, lower back and pelvis level	0.122	0.878	0.000
S35.7 Injury of multiple blood vessels at abdomen, lower back and pelvis level	0.122	0.878	0.000
S35.5 Injury of iliac blood vessels	0.122	0.878	0.000
S35.4 Injury of renal blood vessels	0.122	0.878	0.000
S35.3 Injury of portal or splenic vein	0.122	0.878	0.000
S35.1 Injury of inferior vena cava	0.122	0.878	0.000
S35.0 Injury of abdominal aorta	0.122	0.878	0.000
S11 Open wound of neck	0.121	0.878	0.000
S36.11 Injury of liver or gallbladder (with open wound into cavity)	0.121	0.879	0.000
T29 Burns and corrosions of multiple body regions	0.120	0.880	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.120	0.880	0.000
S27.8 Injury of other specified intrathoracic organs	0.120	0.880	0.000
S37.0 Injury of kidney	0.120	0.880	0.000
T35 Frostbite involving multiple body regions and unspecified frostbite	0.120	0.880	0.000
T34 Frostbite with tissue necrosis	0.120	0.880	0.000
T33 Superficial frostbite	0.120	0.880	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.119	0.880	0.000
S75.0 Injury of femoral artery	0.119	0.881	0.000
S37.3 Injury of urethra	0.119	0.881	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.119	0.881	0.000
S22.80 Fracture of other parts of bony thorax (closed)	0.119	0.881	0.000
S22.91 Fracture of bony thorax, part unspecified (open)	0.119	0.881	0.000
S22.90 Fracture of bony thorax, part unspecified (closed)	0.119	0.881	0.000
S21.1 Open wound of front wall of thorax	0.119	0.881	0.000
S25.9 Injury of unspecified blood vessel of thorax	0.118	0.882	0.000
S25.8 Injury of other blood vessels of thorax	0.118	0.882	0.000
S25.7 Injury of multiple blood vessels of thorax	0.118	0.882	0.000
S25.5 Injury of intercostal blood vessels	0.118	0.882	0.000
S25.4 Injury of pulmonary blood vessels	0.118	0.882	0.000
S25.3 Injury of innominate or subclavian vein	0.118	0.882	0.000
S25.2 Injury of superior vena cava	0.118	0.882	0.000
S25.1 Injury of innominate or subclavian artery	0.118	0.882	0.000
S25.0 Injury of thoracic aorta	0.118	0.882	0.000
S26.9 Injury of heart, unspecified	0.118	0.882	0.000
S26.8 Other injuries of heart	0.118	0.882	0.000
S26.0 Injury of heart with haemopericardium	0.118	0.882	0.000
S28.1 Traumatic amputation of part of thorax	0.118	0.882	0.000
S28.0 Crushed chest	0.118	0.882	0.000
S37.8 Injury of other pelvic organs	0.118	0.882	0.000
S37.7 Injury of multiple pelvic organs	0.118	0.882	0.000
S37.6 Injury of uterus	0.118	0.882	0.000
S37.5 Injury of Fallopian tube	0.118	0.882	0.000
S37.4 Injury of ovary	0.118	0.882	0.000
S37.1 Injury of ureter	0.118	0.882	0.000
T32 Corrosions classified according to extent of body surface involved	0.118	0.882	0.000
T28 Burn and corrosion of other internal organs	0.118	0.882	0.000
T27 Burn and corrosion of respiratory tract	0.118	0.882	0.000
S72.91 Fracture of femur, part unspecified (open)	0.117	0.883	0.000
S32.2 Fracture of coccyx	0.117	0.883	0.000
S12.7 Multiple fractures of cervical spine	0.117	0.883	0.000
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.116	0.884	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.116	0.884	0.000
S10 Superficial injury of neck	0.116	0.884	0.000
S27.1 Traumatic haemothorax	0.116	0.884	0.000
S32.1 Fracture of sacrum	0.116	0.884	0.000
S37.9 Injury of unspecified pelvic organ	0.115	0.884	0.000
T26 Burn and corrosion confined to eye and adnexa	0.115	0.885	0.000
S32.0 Fracture of lumbar vertebra	0.115	0.885	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.115	0.885	0.000
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.114	0.885	0.000
S71.7 Multiple open wounds of of hip and thigh	0.114	0.885	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.114	0.886	0.000
S22.3 Fracture of rib	0.114	0.886	0.000
S38.3 Traumatic amputation of other and unspecified parts of abdomen, lower back and pelvis	0.114	0.886	0.000
S38.2 Traumatic amputation of external genital organs	0.114	0.886	0.000
S38.1 Crushing injury of other and unspecified parts of abdomen, lower back and pelvis	0.114	0.886	0.000
S38.0 Crushing injury of external genital organs	0.114	0.886	0.000
S12.9 Fracture of neck, part unspecified	0.114	0.886	0.000
S79.9 Unspecified injury of hip and thigh	0.114	0.886	0.000
S34.8 Injury of other and unspecified nerves at abdomen, lower back and pelvis level	0.113	0.886	0.000
S34.6 Injury of peripheral nerve(s) of abdomen, lower back and pelvis	0.113	0.886	0.000
S34.5 Injury of lumbar, sacral and pelvic sympathetic nerves	0.113	0.886	0.000
S34.4 Injury of lumbosacral plexus	0.113	0.886	0.000
S34.3 Injury of cauda equina	0.113	0.886	0.000
S34.0 Concussion and oedema of lumbar spinal cord	0.113	0.886	0.000
S23.5 Sprain and strain of other and unspecified parts of thorax	0.113	0.886	0.000
S23.3 Sprain and strain of thoracic spine	0.113	0.886	0.000
S23.2 Dislocation of other and unspecified parts of thorax	0.113	0.886	0.000
S23.1 Dislocation of thoracic vertebra	0.113	0.886	0.000
S23.0 Traumatic rupture of thoracic intervertebral disk	0.113	0.886	0.000
S72.4 Fracture of lower end of femur	0.113	0.887	0.000
T95.2 Sequelae of burn, corrosion and frostbite of upper limb	0.112	0.887	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.112	0.888	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.112	0.888	0.000
S75.9 Injury of unspecified blood vessel at hip and thigh level	0.112	0.888	0.000
S75.8 Injury of other blood vessels at hip and thigh level	0.112	0.888	0.000
S75.7 Injury of multiple blood vessels at hip and thigh level	0.112	0.888	0.000
S75.2 Injury of greater saphenous vein at hip and thigh level	0.112	0.888	0.000
S75.1 Injury of femoral vein at hip and thigh level	0.112	0.888	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.112	0.888	0.000
T21 Burn and corrosion of trunk	0.111	0.889	0.000
T06 Other injuries involving multiple body regions, not elsewhere classified	0.111	0.889	0.000
S89 Other and unspecified injuries of lower leg	0.111	0.889	0.000
S76.3 Injury of muscle and tendon of the posterior muscle group at thigh level	0.110	0.889	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.110	0.889	0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.110	0.890	0.000
S36.40 Injury of small intestine (without open wound into cavity)	0.110	0.890	0.000
T95.3 Sequelae of burn, corrosion and frostbite of lower limb	0.110	0.890	0.000
S12.8 Fracture of other parts of neck	0.109	0.891	0.000
T31 Burns classified according to extent of body surface involved	0.109	0.891	0.000
S32.30 Fracture of ilium (closed)	0.109	0.891	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.109	0.891	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.109	0.891	0.000
S36.50 Injury of colon (without open wound into cavity)	0.108	0.891	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.108	0.892	0.000
S20 Superficial injury of thorax	0.107	0.893	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.107	0.893	0.000
S76.4 Injury of other and unspecified muscles and tendons at thigh level	0.107	0.893	0.000
S30.1 Contusion of abdominal wall	0.107	0.893	0.000
S23.4 Sprain and strain of ribs and sternum	0.107	0.893	0.000
S70.7 Multiple superficial injuries of hip and thigh	0.107	0.893	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.107	0.893	0.000
T00 Superficial injuries involving multiple body regions	0.107	0.893	0.000
S74.9 Injury of unspecified nerve at hip and thigh level	0.106	0.893	0.000
S74.8 Injury of other nerves at hip and thigh level	0.106	0.893	0.000
S74.7 Injury of multiple nerves at hip and thigh level	0.106	0.893	0.000
S74.2 Injury of cutaneous sensory nerve at hip and thigh level	0.106	0.893	0.000
S74.1 Injury of femoral nerve at hip and thigh level	0.106	0.893	0.000
S74.0 Injury of sciatic nerve at hip and thigh level	0.106	0.893	0.000
S77.2 Crushing injury of hip with thigh	0.106	0.893	0.000
S77.1 Crushing injury of thigh	0.106	0.893	0.000
S77.0 Crushing injury of hip	0.106	0.893	0.000
S78.9 Traumatic amputation of hip and thigh, level unspecified	0.106	0.893	0.000
S78.1 Traumatic amputation at level between hip and knee	0.106	0.893	0.000
S78.0 Traumatic amputation at hip joint	0.106	0.893	0.000
S76.1 Injury of quadriceps muscle and tendon	0.106	0.893	0.000
S76.7 Injury of multiple muscles and tendons at hip and thigh level	0.106	0.893	0.000
S76.2 Injury of adductor muscle and tendon of thigh	0.106	0.893	0.000
S12.0 Fracture of first cervical vertebra	0.106	0.894	0.000
S36.80 Injury of other intra-abdominal organs (without open wound into cavity)	0.106	0.894	0.000
S79.7 Multiple injuries of hip and thigh	0.106	0.894	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.106	0.894	0.000
T05 Traumatic amputations involving multiple body regions	0.105	0.895	0.000
T04 Crushing injuries involving multiple body regions	0.105	0.895	0.000
T03 Dislocations, sprains and strains involving multiple body regions	0.105	0.895	0.000
T07 Unspecified multiple injuries	0.105	0.895	0.000
T98.2 Sequelae of certain early complications of trauma	0.105	0.895	0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.105	0.895	0.000
S70.8 Other superficial injuries of hip and thigh	0.104	0.895	0.000
S36.41 Injury of small intestine (with open wound into cavity)	0.104	0.896	0.000
S14.1 Other and unspecified injuries of cervical spinal cord	0.104	0.896	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.104	0.896	0.000
S29.8 Other specified injuries of thorax	0.104	0.896	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.104	0.896	0.000
S36.51 Injury of colon (with open wound into cavity)	0.103	0.896	0.000
S34.2 Injury of nerve root of lumbar and sacral spine	0.103	0.897	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.097	0.897	0.006
S32.5 Fracture of pubis	0.103	0.897	0.000
S60-S69 Injuries to the wrist and hand	0.103	0.897	0.000
S72.1 Pertrochanteric fracture	0.102	0.897	0.000
S36.81 Injury of other intra-abdominal organs (with open wound into cavity)	0.102	0.897	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.102	0.898	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.102	0.898	0.000
S76.0 Injury of muscle and tendon of hip	0.101	0.898	0.000
S30.0 Contusion of lower back and pelvis	0.101	0.899	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.101	0.899	0.000
S19.9 Unspecified injury of neck	0.101	0.899	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.100	0.900	0.000
S14.3 Injury of brachial plexus	0.100	0.900	0.000
S36.21 Injury of pancreas (with open wound into cavity)	0.100	0.900	0.000
S36.20 Injury of pancreas (without open wound into cavity)	0.100	0.900	0.000
S36.31 Injury of stomach (with open wound into cavity)	0.100	0.900	0.000
S36.30 Injury of stomach (without open wound into cavity)	0.100	0.900	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations