TreeWAS – Variant ID: rs3117027

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.022	0.978
K90.0 Coeliac disease	0.000	0.176	0.824
M06.9 Rheumatoid arthritis, unspecified	0.000	0.190	0.810
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.199	0.801
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.239	0.761
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.248	0.752
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.272	0.728
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.298	0.702
E03 Other hypothyroidism	0.000	0.302	0.698
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.306	0.694
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.334	0.666
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.334	0.666
E03.8 Other specified hypothyroidism	0.000	0.392	0.608
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.436	0.564
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.448	0.552
E03.1 Congenital hypothyroidism without goitre	0.000	0.465	0.534
K90 Intestinal malabsorption	0.000	0.475	0.525
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.488	0.512
M06 Other rheumatoid arthritis	0.000	0.491	0.509
E03.5 Myxoedema coma	0.000	0.500	0.500
E03.4 Atrophy of thyroid (acquired)	0.000	0.500	0.500
E03.3 Postinfectious hypothyroidism	0.000	0.500	0.500
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.534	0.466
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.540	0.460
M06.3 Rheumatoid nodule	0.000	0.546	0.453
M06.4 Inflammatory polyarthropathy	0.000	0.578	0.422
M06.34 Rheumatoid nodule (Hand)	0.000	0.589	0.411
K90.3 Pancreatic steatorrhoea	0.000	0.623	0.377
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.623	0.377
K90.1 Tropical sprue	0.000	0.623	0.377
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.626	0.374
K90.9 Intestinal malabsorption, unspecified	0.000	0.626	0.374
M06.2 Rheumatoid bursitis	0.000	0.635	0.365
M06.1 Adult-onset Still's disease	0.000	0.635	0.365
K90.8 Other intestinal malabsorption	0.000	0.636	0.364
M06.8 Other specified rheumatoid arthritis	0.000	0.649	0.351
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.657	0.343
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.665	0.335
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.675	0.325
M06.38 Rheumatoid nodule (Other)	0.000	0.675	0.325
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.675	0.325
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.675	0.325
M06.33 Rheumatoid nodule (Forearm)	0.000	0.675	0.325
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.675	0.325
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.697	0.303
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.697	0.303
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.697	0.303
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.697	0.303
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.697	0.303
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.697	0.303
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.697	0.303
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.699	0.301
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.712	0.288
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.718	0.282
M06.0 Seronegative rheumatoid arthritis	0.000	0.731	0.269
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.738	0.262
M06.18 Adult-onset Still's disease (Other)	0.000	0.738	0.262
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.738	0.262
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.738	0.262
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.738	0.262
M06.14 Adult-onset Still's disease (Hand)	0.000	0.738	0.262
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.738	0.262
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.738	0.262
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.738	0.262
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.738	0.262
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.738	0.262
M06.28 Rheumatoid bursitis (Other)	0.000	0.738	0.262
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.738	0.262
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.738	0.262
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.738	0.262
M06.24 Rheumatoid bursitis (Hand)	0.000	0.738	0.262
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.738	0.262
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.738	0.262
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.738	0.262
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.738	0.262
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.748	0.251
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.748	0.251
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.748	0.251
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.748	0.251
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.748	0.251
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.748	0.251
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.748	0.251
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.748	0.251
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.748	0.251
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.000	0.763	0.237
E00-E07 Disorders of thyroid gland	0.000	0.786	0.213
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.793	0.207
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.799	0.201
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.805	0.195
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.807	0.193
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.807	0.193
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.807	0.193
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.807	0.193
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.807	0.193
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.815	0.185
E07 Other disorders of thyroid	0.000	0.823	0.177
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.826	0.174
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.833	0.167
E05.9 Thyrotoxicosis, unspecified	0.000	0.844	0.156
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.845	0.155
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.847	0.153
E00 Congenital iodine-deficiency syndrome	0.000	0.847	0.153
E07.9 Disorder of thyroid, unspecified	0.000	0.852	0.148
E05.5 Thyroid crisis or storm	0.000	0.856	0.144
E05.4 Thyrotoxicosis factitia	0.000	0.856	0.144
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.856	0.144
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.856	0.144
E05.8 Other thyrotoxicosis	0.000	0.865	0.135
E07.8 Other specified disorders of thyroid	0.000	0.869	0.131
E07.1 Dyshormogenetic goitre	0.000	0.873	0.127
E07.0 Hypersecretion of calcitonin	0.000	0.873	0.127
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.874	0.126
J47 Bronchiectasis	0.000	0.876	0.124
E02 Subclinical iodine-deficiency hypothyroidism	0.001	0.881	0.118
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.890	0.110
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.890	0.110
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.890	0.110
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.890	0.110
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.890	0.110
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.890	0.110
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.890	0.110
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.890	0.110
K90-K93 Other diseases of the digestive system	0.000	0.917	0.083
E06 Thyroiditis	0.001	0.930	0.069
K91.4 Colostomy and enterostomy malfunction	0.000	0.939	0.061
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.940	0.060
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.945	0.055
E06.4 Drug-induced thyroiditis	0.001	0.950	0.050
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.001	0.950	0.050
E06.0 Acute thyroiditis	0.001	0.950	0.050
E06.5 Other chronic thyroiditis	0.001	0.952	0.048
E06.1 Subacute thyroiditis	0.001	0.954	0.045
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.957	0.043
K93.1 Megacolon in Chagas' disease	0.000	0.957	0.043
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.957	0.043
E06.9 Thyroiditis, unspecified	0.001	0.961	0.039
K91.5 Postcholecystectomy syndrome	0.000	0.962	0.038
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.965	0.035
K91.1 Postgastric surgery syndromes	0.000	0.966	0.034
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.968	0.031
K91.9 Postprocedural disorder of digestive system, unspecified	0.001	0.973	0.026
I61.9 Intracerebral haemorrhage, unspecified	0.024	0.976	0.000
J40-J47 Chronic lower respiratory diseases	0.000	0.976	0.024
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.978	0.022
J44 Other chronic obstructive pulmonary disease	0.000	0.980	0.020
Z83.5 Family history of eye and ear disorders	0.000	0.980	0.020
E06.3 Autoimmune thyroiditis	0.001	0.980	0.019
J42 Unspecified chronic bronchitis	0.000	0.980	0.020
J41 Simple and mucopurulent chronic bronchitis	0.000	0.981	0.019
J45 Asthma	0.000	0.981	0.019
I61 Intracerebral haemorrhage	0.018	0.982	0.000
J45.9 Asthma, unspecified	0.000	0.983	0.017
K91.3 Postoperative intestinal obstruction	0.000	0.984	0.016
J41.0 Simple chronic bronchitis	0.000	0.984	0.016
I61.8 Other intracerebral haemorrhage	0.016	0.984	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.015	0.985	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.015	0.985	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.985	0.015
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.014	0.986	0.000
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.000	0.986	0.014
J41.1 Mucopurulent chronic bronchitis	0.000	0.986	0.014
M80.9 Unspecified osteoporosis with pathological fracture	0.014	0.986	0.000
J45.1 Nonallergic asthma	0.000	0.986	0.014
J45.8 Mixed asthma	0.000	0.986	0.013
I61.6 Intracerebral haemorrhage, multiple localised	0.013	0.986	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.013	0.987	0.000
N80.8 Other endometriosis	0.000	0.987	0.013
I61.3 Intracerebral haemorrhage in brain stem	0.013	0.987	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.013	0.987	0.000
M05-M14 Inflammatory polyarthropathies	0.000	0.987	0.013
E04 Other non-toxic goitre	0.003	0.987	0.010
N87.1 Moderate cervical dysplasia	0.013	0.987	0.000
M80 Osteoporosis with pathological fracture	0.013	0.987	0.000
K72.9 Hepatic failure, unspecified	0.012	0.988	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.012	0.988	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.988	0.012
M84.0 Malunion of fracture	0.012	0.988	0.000
J43 Emphysema	0.000	0.988	0.012
M84 Disorders of continuity of bone	0.011	0.989	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.011	0.989	0.000
M80-M85 Disorders of bone density and structure	0.011	0.989	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.011	0.989	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.989	0.011
M84.04 Malunion of fracture (Hand)	0.011	0.989	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.011	0.989	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.011	0.989	0.000
M84.02 Malunion of fracture (Upper arm)	0.011	0.989	0.000
K25.3 Acute without haemorrhage or perforation	0.010	0.990	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.010	0.990	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.010	0.990	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.010	0.990	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.010	0.990	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.010	0.990	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.010	0.990	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.010	0.990	0.000
U80.1 Methicillin resistant agent	0.010	0.990	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.010	0.990	0.000
M81 Osteoporosis without pathological fracture	0.010	0.990	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.990	0.010
M80.8 Other osteoporosis with pathological fracture	0.009	0.990	0.000
E04.8 Other specified non-toxic goitre	0.003	0.990	0.007
M80.0 Postmenopausal osteoporosis with pathological fracture	0.009	0.990	0.000
M85 Other disorders of bone density and structure	0.009	0.990	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.009	0.991	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.009	0.991	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.009	0.991	0.000
M84.3 Stress fracture, not elsewhere classified	0.009	0.991	0.000
M12 Other specific arthropathies	0.000	0.991	0.009
M08 Juvenile arthritis	0.000	0.991	0.009
J43.8 Other emphysema	0.000	0.991	0.009
M81.9 Osteoporosis, unspecified	0.009	0.991	0.000
M84.09 Malunion of fracture (Site unspecified)	0.009	0.991	0.000
M84.08 Malunion of fracture (Other)	0.009	0.991	0.000
M84.00 Malunion of fracture (Multiple sites)	0.009	0.991	0.000
M84.4 Pathological fracture, not elsewhere classified	0.009	0.991	0.000
J43.1 Panlobular emphysema	0.000	0.991	0.008
J43.0 MacLeod's syndrome	0.000	0.991	0.008
M84.2 Delayed union of fracture	0.009	0.991	0.000
M83 Adult osteomalacia	0.008	0.992	0.000
M84.9 Disorder of continuity of bone, unspecified	0.008	0.992	0.000
M85.0 Fibrous dysplasia (monostotic)	0.008	0.992	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.008	0.992	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.008	0.992	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.008	0.992	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.008	0.992	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.008	0.992	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.008	0.992	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.008	0.992	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.008	0.992	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.008	0.992	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.008	0.992	0.000
K92 Other diseases of digestive system	0.000	0.992	0.008
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.008	0.992	0.000
J45.0 Predominantly allergic asthma	0.000	0.992	0.008
M84.01 Malunion of fracture (Shoulder region)	0.008	0.992	0.000
D69.9 Haemorrhagic condition, unspecified	0.000	0.992	0.008
U80 Agent resistant to penicillin and related antibiotics	0.008	0.992	0.000
J34.3 Hypertrophy of nasal turbinates	0.008	0.992	0.000
M05 Seropositive rheumatoid arthritis	0.000	0.992	0.008
H60.9 Otitis externa, unspecified	0.000	0.992	0.008
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.008	0.992	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.008	0.992	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.992	0.008
M85.2 Hyperostosis of skull	0.008	0.992	0.000
M85.9 Disorder of bone density and structure, unspecified	0.008	0.992	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.008	0.992	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.008	0.992	0.000
D69 Purpura and other haemorrhagic conditions	0.000	0.992	0.008
M84.8 Other disorders of continuity of bone	0.007	0.992	0.000
Z83 Family history of other specific disorders	0.000	0.992	0.008
D69.0 Allergic purpura	0.000	0.992	0.008
J43.2 Centrilobular emphysema	0.000	0.992	0.007
M11 Other crystal arthropathies	0.000	0.993	0.007
M84.06 Malunion of fracture (Lower leg)	0.007	0.993	0.000
M81.8 Other osteoporosis	0.007	0.993	0.000
M81.2 Osteoporosis of disuse	0.007	0.993	0.000
Q05.9 Spina bifida, unspecified	0.000	0.993	0.007
M81.91 Osteoporosis, unspecified (Shoulder region)	0.007	0.993	0.000
M81.98 Osteoporosis, unspecified (Other)	0.007	0.993	0.000
E04.0 Non-toxic diffuse goitre	0.003	0.993	0.004
M12.3 Palindromic rheumatism	0.000	0.993	0.007
M80.88 Other osteoporosis with pathological fracture (Other)	0.007	0.993	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.007	0.993	0.000
F20.0 Paranoid schizophrenia	0.007	0.993	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.007	0.993	0.000
M81.6 Localised osteoporosis [Lequesne]	0.007	0.993	0.000
M81.5 Idiopathic osteoporosis	0.007	0.993	0.000
M81.1 Postoophorectomy osteoporosis	0.007	0.993	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.000	0.993	0.007
M09.2 Juvenile arthritis in ulcerative colitis	0.000	0.993	0.007
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.000	0.993	0.007
M09.0 Juvenile arthritis in psoriasis	0.000	0.993	0.007
M81.3 Postsurgical malabsorption osteoporosis	0.007	0.993	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.007	0.993	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.007	0.993	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.007	0.993	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.007	0.993	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.007	0.993	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.007	0.993	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.007	0.993	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.007	0.993	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.007	0.993	0.000
D69.4 Other primary thrombocytopenia	0.000	0.993	0.007
L71.9 Rosacea, unspecified	0.007	0.993	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.007	0.993	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.007	0.993	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.007	0.993	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.007	0.993	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.007	0.993	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.007	0.993	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.007	0.993	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.007	0.993	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.007	0.993	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.007	0.993	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.007	0.993	0.000
M85.5 Aneurysmal bone cyst	0.007	0.993	0.000
M85.4 Solitary bone cyst	0.007	0.993	0.000
M85.3 Osteitis condensans	0.007	0.993	0.000
M85.1 Skeletal fluorosis	0.007	0.993	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.007	0.993	0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.007	0.993	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.007	0.993	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.007	0.993	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.007	0.993	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.007	0.993	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.007	0.993	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.007	0.993	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.007	0.993	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.007	0.993	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.007	0.993	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.007	0.993	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.007	0.993	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.007	0.993	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.007	0.993	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.007	0.993	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.007	0.993	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.007	0.993	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.007	0.993	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.007	0.993	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.007	0.993	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.007	0.993	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.007	0.993	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.007	0.993	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.007	0.993	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.007	0.993	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.007	0.993	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.007	0.993	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.007	0.993	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.007	0.993	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.007	0.993	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.007	0.993	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.007	0.993	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.007	0.993	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.007	0.993	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.007	0.993	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.007	0.993	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.007	0.993	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.007	0.993	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.007	0.993	0.000
H60 Otitis externa	0.000	0.993	0.007
M12.8 Other specific arthropathies, not elsewhere classified	0.000	0.993	0.007
M12.5 Traumatic arthropathy	0.000	0.993	0.007
M12.4 Intermittent hydrarthrosis	0.000	0.993	0.007
M12.1 Kaschin-Beck disease	0.000	0.993	0.007
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.000	0.993	0.007
M08.9 Juvenile arthritis, unspecified	0.000	0.993	0.007
M08.8 Other juvenile arthritis	0.000	0.993	0.007
M08.4 Pauciarticular juvenile arthritis	0.000	0.993	0.007
M08.3 Juvenile polyarthritis (seronegative)	0.000	0.993	0.007
M08.2 Juvenile arthritis with systemic onset	0.000	0.993	0.007
M08.1 Juvenile ankylosing spondylitis	0.000	0.993	0.007
M81.0 Postmenopausal osteoporosis	0.007	0.993	0.000
M82 Osteoporosis in diseases classified elsewhere	0.007	0.993	0.000
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.993	0.007
M10 Gout	0.000	0.993	0.007
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.007	0.993	0.000
M13 Other arthritis	0.000	0.993	0.007
M81.92 Osteoporosis, unspecified (Upper arm)	0.007	0.993	0.000
M81.4 Drug-induced osteoporosis	0.007	0.993	0.000
M14 Arthropathies in other diseases classified elsewhere	0.000	0.993	0.006
M81.90 Osteoporosis, unspecified (Multiple sites)	0.007	0.993	0.000
M84.26 Delayed union of fracture (Lower leg)	0.006	0.993	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.007	0.993	0.000
I89.0 Lymphoedema, not elsewhere classified	0.000	0.993	0.007
Z83.1 Family history of other infectious and parasitic diseases	0.000	0.993	0.007
M85.20 Hyperostosis of skull-Mult sites	0.007	0.993	0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.007	0.993	0.000
D69.6 Thrombocytopenia, unspecified	0.000	0.993	0.007
M83.1 Senile osteomalacia	0.006	0.993	0.000
Z83.6 Family history of diseases of the respiratory system	0.000	0.993	0.007
J46 Status asthmaticus	0.000	0.993	0.006
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.006	0.993	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.006	0.993	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.006	0.993	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.006	0.993	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.006	0.993	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.006	0.993	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.006	0.993	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.006	0.993	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.000	0.993	0.007
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.006	0.993	0.000
I89.1 Lymphangitis	0.000	0.993	0.007
M08.0 Juvenile rheumatoid arthritis	0.000	0.993	0.006
M07 Psoriatic and enteropathic arthropathies	0.000	0.993	0.006
U80.8 Agent resistant to other penicillin-related antibiotic	0.006	0.993	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.006	0.994	0.000
M84.28 Delayed union of fracture (Other)	0.006	0.994	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.006	0.994	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.006	0.994	0.000
M84.24 Delayed union of fracture (Hand)	0.006	0.994	0.000
M84.23 Delayed union of fracture (Forearm)	0.006	0.994	0.000
M84.22 Delayed union of fracture (Upper arm)	0.006	0.994	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.006	0.994	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.006	0.994	0.000
M83.9 Adult osteomalacia, unspecified	0.006	0.994	0.000
M83.5 Other drug-induced osteomalacia in adults	0.006	0.994	0.000
M83.4 Aluminum bone disease	0.006	0.994	0.000
M83.3 Adult osteomalacia due to malnutrition	0.006	0.994	0.000
M83.2 Adult osteomalacia due to malabsorption	0.006	0.994	0.000
M83.0 Puerperal osteomalacia	0.006	0.994	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.006	0.994	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.006	0.994	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.006	0.994	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.006	0.994	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.006	0.994	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.006	0.994	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.006	0.994	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.006	0.994	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.006	0.994	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.006	0.994	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.006	0.994	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.006	0.994	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.006	0.994	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.006	0.994	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.006	0.994	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.006	0.994	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.006	0.994	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.006	0.994	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.006	0.994	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.006	0.994	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.006	0.994	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.006	0.994	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.006	0.994	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.006	0.994	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.006	0.994	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.006	0.994	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.006	0.994	0.000
M84.03 Malunion of fracture (Forearm)	0.006	0.994	0.000
H60.1 Cellulitis of external ear	0.000	0.994	0.006
M83.8 Other adult osteomalacia	0.006	0.994	0.000
D69.2 Other nonthrombocytopenic purpura	0.000	0.994	0.006
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.994	0.006
M12.2 Villonodular synovitis (pigmented)	0.000	0.994	0.006
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.006	0.994	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.994	0.006
M05.1 Rheumatoid lung disease	0.000	0.994	0.006
M05.0 Felty's syndrome	0.000	0.994	0.006
M85.8 Other specified disorders of bone density and structure	0.006	0.994	0.000
M12.39 Palindromic rheumatism (Site unspecified)	0.000	0.994	0.006
M85.29 Hyperostosis of skull-Site unspec	0.006	0.994	0.000
M85.28 Hyperostosis of skull-Other	0.006	0.994	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.006	0.994	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.006	0.994	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.006	0.994	0.000
M85.24 Hyperostosis of skull-Hand	0.006	0.994	0.000
M85.23 Hyperostosis of skull-Forearm	0.006	0.994	0.000
M85.22 Hyperostosis of skull-Upper arm	0.006	0.994	0.000
M85.21 Hyperostosis of skull-Shldr region	0.006	0.994	0.000
L40.9 Psoriasis, unspecified	0.006	0.994	0.000
M05.8 Other seropositive rheumatoid arthritis	0.000	0.994	0.006
M85.98 Disorder of bone density and structure, unspecified (Other)	0.006	0.994	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.006	0.994	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.006	0.994	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.006	0.994	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.006	0.994	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.006	0.994	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.006	0.994	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.006	0.994	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.006	0.994	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.006	0.994	0.000
K25.4 Chronic or unspecified with haemorrhage	0.006	0.994	0.000
U80.0 Penicillin resistant agent	0.006	0.994	0.000
H60.3 Other infective otitis externa	0.000	0.994	0.006
F20.9 Schizophrenia, unspecified	0.006	0.994	0.000
M05.2 Rheumatoid vasculitis	0.000	0.994	0.006
M85.6 Other cyst of bone	0.006	0.994	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.006	0.994	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.006	0.994	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.006	0.994	0.000
F20 Schizophrenia	0.006	0.994	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.006	0.994	0.000
M84.88 Other disorders of continuity of bone (Other)	0.006	0.994	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.006	0.994	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.006	0.994	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.006	0.994	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.006	0.994	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.006	0.994	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.006	0.994	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.006	0.994	0.000
D69.8 Other specified haemorrhagic conditions	0.000	0.994	0.006
H60.0 Abscess of external ear	0.000	0.994	0.006
M31.3 Wegener's granulomatosis	0.000	0.994	0.006
Z83.0 Family history of human immunodeficiency virus [HIV]	0.000	0.994	0.006
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.006	0.994	0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.000	0.994	0.006
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.005	0.994	0.000
H50.5 Heterophoria	0.006	0.994	0.000
M81.80 Other osteoporosis (Multiple sites)	0.005	0.994	0.000
H60.5 Acute otitis externa, non-infective	0.000	0.994	0.006
M13.8 Other specified arthritis	0.000	0.994	0.006
M81.20 Osteoporosis of disuse (Multiple sites)	0.006	0.994	0.000
H60.4 Cholesteatoma of external ear	0.000	0.994	0.006
M11.1 Familial chondrocalcinosis	0.000	0.994	0.005
M11.0 Hydroxyapatite deposition disease	0.000	0.994	0.005
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.006	0.994	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.000	0.994	0.006
K92.9 Disease of digestive system, unspecified	0.000	0.994	0.006
U51.1 Previously admitted to a psychiatric hospital of the provider	0.006	0.994	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.005	0.994	0.000
M81.28 Osteoporosis of disuse (Other)	0.005	0.994	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations