TreeWAS – Variant ID: rs3130309

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.000	1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.000	1.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
G35 Multiple sclerosis	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
G35-G37 Demyelinating diseases of the central nervous system	1.000	0.000	0.000
M06 Other rheumatoid arthritis	0.000	0.000	1.000
E27 Other disorders of adrenal gland	1.000	0.000	0.000
E20-E35 Disorders of other endocrine glands	0.999	0.001	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.001	0.999
B37.8 Candidiasis of other sites	0.999	0.001	0.000
E27.1 Primary adrenocortical insufficiency	0.999	0.001	0.000
Chapter VI Diseases of the nervous system	0.999	0.001	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.998	0.002	0.000
B37 Candidiasis	0.998	0.002	0.000
Chapter I Certain infectious and parasitic diseases	0.998	0.002	0.000
# Top node	0.998	0.002	0.000
B35-B49 Mycoses	0.996	0.004	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.004	0.996
D50-D53 Nutritional anaemias	0.995	0.005	0.000
M05 Seropositive rheumatoid arthritis	0.000	0.007	0.993
M05-M14 Inflammatory polyarthropathies	0.000	0.012	0.988
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.016	0.984
D51 Vitamin B12 deficiency anaemia	0.983	0.017	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.976	0.024	0.000
E04 Other non-toxic goitre	0.974	0.026	0.000
B07 Viral warts	0.969	0.031	0.000
M06.3 Rheumatoid nodule	0.000	0.031	0.969
D52 Folate deficiency anaemia	0.968	0.032	0.000
G37 Other demyelinating diseases of central nervous system	0.967	0.033	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.952	0.048	0.000
G40-G47 Episodic and paroxysmal disorders	0.952	0.048	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.050	0.950
D52.9 Folate deficiency anaemia, unspecified	0.949	0.051	0.000
E27.2 Addisonian crisis	0.943	0.057	0.000
E04.0 Non-toxic diffuse goitre	0.938	0.062	0.000
D80-D89 Certain disorders involving the immune mechanism	0.937	0.063	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.063	0.937
E04.2 Non-toxic multinodular goitre	0.936	0.064	0.000
E50-E64 Other nutritional deficiencies	0.929	0.071	0.000
B37.9 Candidiasis, unspecified	0.929	0.071	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.926	0.074	0.000
G40 Epilepsy	0.925	0.075	0.000
M06.34 Rheumatoid nodule (Hand)	0.000	0.078	0.922
B20-B24 Human immunodeficiency virus [HIV] disease	0.916	0.084	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.914	0.086	0.000
M06.0 Seronegative rheumatoid arthritis	0.000	0.088	0.912
G20-G26 Extrapyramidal and movement disorders	0.911	0.089	0.000
K90 Intestinal malabsorption	0.906	0.094	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.904	0.096	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.902	0.098	0.000
E27.8 Other specified disorders of adrenal gland	0.901	0.099	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.890	0.110	0.000
M06.4 Inflammatory polyarthropathy	0.000	0.115	0.885
G45.9 Transient cerebral ischaemic attack, unspecified	0.883	0.117	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.882	0.118	0.000
G20 Parkinson's disease	0.877	0.123	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.125	0.875
D69 Purpura and other haemorrhagic conditions	0.864	0.136	0.000
B25-B34 Other viral diseases	0.863	0.137	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.139	0.861
D55-D59 Haemolytic anaemias	0.858	0.142	0.000
D86 Sarcoidosis	0.854	0.146	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.853	0.147	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.149	0.851
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.847	0.153	0.000
E55 Vitamin D deficiency	0.846	0.154	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.156	0.844
G30-G32 Other degenerative diseases of the nervous system	0.841	0.159	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.163	0.837
E27.9 Disorder of adrenal gland, unspecified	0.828	0.172	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.173	0.827
D59 Acquired haemolytic anaemia	0.821	0.179	0.000
B24 Unspecified human immunodeficiency virus [HIV] disease	0.817	0.183	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.816	0.184	0.000
E22 Hyperfunction of pituitary gland	0.815	0.185	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.813	0.187	0.000
B25 Cytomegaloviral disease	0.808	0.192	0.000
E07 Other disorders of thyroid	0.808	0.192	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.808	0.192	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.193	0.807
A63.0 Anogenital (venereal) warts	0.805	0.195	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.804	0.196	0.000
E31 Polyglandular dysfunction	0.804	0.196	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.800	0.200	0.000
G40.5 Special epileptic syndromes	0.799	0.201	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.797	0.203	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.206	0.794
E34 Other endocrine disorders	0.793	0.207	0.000
B37.1 Pulmonary candidiasis	0.793	0.207	0.000
E20 Hypoparathyroidism	0.792	0.208	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.791	0.209	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.210	0.790
E55.9 Vitamin D deficiency, unspecified	0.786	0.214	0.000
E51 Thiamine deficiency	0.780	0.220	0.000
L50-L54 Urticaria and erythema	0.780	0.220	0.000
L10-L14 Bullous disorders	0.779	0.221	0.000
A30-A49 Other bacterial diseases	0.777	0.223	0.000
A80-A89 Viral infections of the central nervous system	0.777	0.223	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.226	0.774
D68 Other coagulation defects	0.774	0.226	0.000
D86.3 Sarcoidosis of skin	0.771	0.229	0.000
M05.8 Other seropositive rheumatoid arthritis	0.000	0.230	0.770
G37.8 Other specified demyelinating diseases of central nervous system	0.770	0.230	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.237	0.763
D59.1 Other autoimmune haemolytic anaemias	0.763	0.237	0.000
B25.9 Cytomegaloviral disease, unspecified	0.762	0.238	0.000
D69.6 Thrombocytopenia, unspecified	0.762	0.238	0.000
G00 Bacterial meningitis, not elsewhere classified	0.761	0.239	0.000
K90.9 Intestinal malabsorption, unspecified	0.761	0.239	0.000
E07.8 Other specified disorders of thyroid	0.759	0.241	0.000
D72 Other disorders of white blood cells	0.757	0.243	0.000
G41 Status epilepticus	0.757	0.243	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.753	0.247	0.000
D69.4 Other primary thrombocytopenia	0.753	0.247	0.000
L13 Other bullous disorders	0.751	0.249	0.000
G44 Other headache syndromes	0.749	0.251	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.745	0.255	0.000
B37.4 Candidiasis of other urogenital sites	0.745	0.255	0.000
B01 Varicella [chickenpox]	0.744	0.256	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.257	0.743
E63 Other nutritional deficiencies	0.740	0.260	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.261	0.739
D72.8 Other specified disorders of white blood cells	0.737	0.263	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.735	0.265	0.000
D69.8 Other specified haemorrhagic conditions	0.734	0.266	0.000
L20-L30 Dermatitis and eczema	0.733	0.267	0.000
D86.9 Sarcoidosis, unspecified	0.732	0.268	0.000
D60-D64 Aplastic and other anaemias	0.732	0.268	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.732	0.268	0.000
L13.0 Dermatitis herpetiformis	0.731	0.269	0.000
B23 Human immunodeficiency virus [HIV] disease resulting in other conditions	0.729	0.271	0.000
E53 Deficiency of other B group vitamins	0.724	0.276	0.000
A41 Other septicaemia	0.722	0.278	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.722	0.278	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.280	0.719
Chapter XVI Certain conditions originating in the perinatal period	0.719	0.281	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.283	0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.283	0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.283	0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.283	0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.283	0.717
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.000	0.283	0.717
M06.1 Adult-onset Still's disease	0.000	0.283	0.717
E27.5 Adrenomedullary hyperfunction	0.717	0.283	0.000
E27.0 Other adrenocortical overactivity	0.717	0.283	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.717	0.283	0.000
E32 Diseases of thymus	0.717	0.283	0.000
E30 Disorders of puberty, not elsewhere classified	0.717	0.283	0.000
E25 Adrenogenital disorders	0.717	0.283	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.716	0.284	0.000
B37.6 Candidal endocarditis	0.715	0.285	0.000
B37.5 Candidal meningitis	0.715	0.285	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.715	0.285	0.000
A75-A79 Rickettsioses	0.715	0.285	0.000
A70-A74 Other diseases caused by chlamydiae	0.715	0.285	0.000
A20-A28 Certain zoonotic bacterial diseases	0.715	0.285	0.000
D82 Immunodeficiency associated with other major defects	0.715	0.285	0.000
B48 Other mycoses, not elsewhere classified	0.714	0.286	0.000
B47 Mycetoma	0.714	0.286	0.000
B46 Zygomycosis	0.714	0.286	0.000
B45 Cryptococcosis	0.714	0.286	0.000
B43 Chromomycosis and phaeomycotic abscess	0.714	0.286	0.000
B42 Sporotrichosis	0.714	0.286	0.000
B41 Paracoccidioidomycosis	0.714	0.286	0.000
B40 Blastomycosis	0.714	0.286	0.000
B39 Histoplasmosis	0.714	0.286	0.000
B38 Coccidioidomycosis	0.714	0.286	0.000
K90.8 Other intestinal malabsorption	0.714	0.286	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.713	0.287	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.713	0.287	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.713	0.287	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.288	0.712
M05.1 Rheumatoid lung disease	0.000	0.288	0.712
M05.0 Felty's syndrome	0.000	0.288	0.712
D61 Other aplastic anaemias	0.710	0.290	0.000
D84 Other immunodeficiencies	0.709	0.291	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.292	0.708
M08 Juvenile arthritis	0.000	0.292	0.708
E70-E90 Metabolic disorders	0.708	0.292	0.000
Chapter XXII Codes for special purposes	0.706	0.294	0.000
M45 Ankylosing spondylitis	0.000	0.295	0.705
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.295	0.705
D51.2 Transcobalamin II deficiency	0.705	0.295	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.705	0.295	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.704	0.296	0.000
B20 Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases	0.704	0.296	0.000
B06 Rubella [German measles]	0.700	0.300	0.000
B05 Measles	0.700	0.300	0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.700	0.300	0.000
B04 Monkeypox	0.700	0.300	0.000
B03 Smallpox	0.700	0.300	0.000
D68.0 Von Willebrand's disease	0.699	0.301	0.000
E04.8 Other specified non-toxic goitre	0.698	0.301	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.697	0.303	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.696	0.303	0.000
G36 Other acute disseminated demyelination	0.696	0.304	0.000
B37.2 Candidiasis of skin and nail	0.696	0.304	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.305	0.694
M06.38 Rheumatoid nodule (Other)	0.000	0.305	0.694
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.305	0.694
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.305	0.694
M06.33 Rheumatoid nodule (Forearm)	0.000	0.305	0.694
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.305	0.694
D52.8 Other folate deficiency anaemias	0.694	0.306	0.000
D52.1 Drug-induced folate deficiency anaemia	0.694	0.306	0.000
D52.0 Dietary folate deficiency anaemia	0.694	0.306	0.000
G37.5 Concentric sclerosis [Balo]	0.693	0.306	0.000
G37.4 Subacute necrotising myelitis	0.693	0.306	0.000
G37.2 Central pontine myelinolysis	0.693	0.306	0.000
G37.1 Central demyelination of corpus callosum	0.693	0.306	0.000
G37.0 Diffuse sclerosis	0.693	0.306	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.692	0.308	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.691	0.309	0.000
D61.9 Aplastic anaemia, unspecified	0.691	0.309	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.691	0.309	0.000
M05.2 Rheumatoid vasculitis	0.000	0.309	0.691
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.690	0.310	0.000
L52 Erythema nodosum	0.690	0.310	0.000
M12 Other specific arthropathies	0.000	0.311	0.689
A40 Streptococcal septicaemia	0.687	0.313	0.000
E05.8 Other thyrotoxicosis	0.687	0.313	0.000
L21 Seborrhoeic dermatitis	0.684	0.316	0.000
A65-A69 Other spirochaetal diseases	0.681	0.318	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.680	0.320	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.680	0.320	0.000
G21 Secondary Parkinsonism	0.680	0.320	0.000
G00.9 Bacterial meningitis, unspecified	0.680	0.320	0.000
L50 Urticaria	0.679	0.321	0.000
E34.0 Carcinoid syndrome	0.677	0.323	0.000
E83 Disorders of mineral metabolism	0.674	0.326	0.000
E83.1 Disorders of iron metabolism	0.674	0.326	0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.674	0.326	0.000
E51.2 Wernicke's encephalopathy	0.674	0.326	0.000
D81 Combined immunodeficiencies	0.672	0.328	0.000
L27 Dermatitis due to substances taken internally	0.672	0.328	0.000
D53 Other nutritional anaemias	0.671	0.329	0.000
G41.0 Grand mal status epilepticus	0.670	0.330	0.000
G24 Dystonia	0.669	0.331	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.668	0.332	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.666	0.334	0.000
E50 Vitamin A deficiency	0.666	0.334	0.000
E60 Dietary zinc deficiency	0.666	0.334	0.000
E59 Dietary selenium deficiency	0.666	0.334	0.000
E54 Ascorbic acid deficiency	0.666	0.334	0.000
E52 Niacin deficiency [pellagra]	0.666	0.334	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.666	0.334	0.000
E31.0 Autoimmune polyglandular failure	0.663	0.336	0.000
D68.9 Coagulation defect, unspecified	0.663	0.337	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.338	0.662
L53 Other erythematous conditions	0.661	0.339	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.658	0.342	0.000
B65-B83 Helminthiases	0.657	0.343	0.000
B22 Human immunodeficiency virus [HIV] disease resulting in other specified diseases	0.657	0.343	0.000
B21 Human immunodeficiency virus [HIV] disease resulting in malignant neoplasms	0.657	0.343	0.000
B00 Herpesviral [herpes simplex] infections	0.657	0.343	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.345	0.655
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.346	0.654
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.346	0.654
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.346	0.654
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.346	0.654
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.346	0.654
B37.7 Candidal septicaemia	0.653	0.347	0.000
B36 Other superficial mycoses	0.653	0.347	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.653	0.347	0.000
G22 Parkinsonism in diseases classified elsewhere	0.653	0.347	0.000
E40-E46 Malnutrition	0.651	0.349	0.000
E22.0 Acromegaly and pituitary gigantism	0.650	0.350	0.000
L21.9 Seborrhoeic dermatitis, unspecified	0.649	0.351	0.000
K90.3 Pancreatic steatorrhoea	0.649	0.351	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.649	0.351	0.000
K90.1 Tropical sprue	0.649	0.351	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.648	0.352	0.000
E21.3 Hyperparathyroidism, unspecified	0.648	0.352	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.647	0.353	0.000
A59 Trichomoniasis	0.646	0.353	0.000
A56 Other sexually transmitted chlamydial diseases	0.646	0.353	0.000
A54 Gonococcal infection	0.646	0.353	0.000
A53 Other and unspecified syphilis	0.646	0.353	0.000
A52 Late syphilis	0.646	0.353	0.000
A51 Early syphilis	0.646	0.353	0.000
A50 Congenital syphilis	0.646	0.353	0.000
A64 Unspecified sexually transmitted disease	0.646	0.353	0.000
A58 Granuloma inguinale	0.646	0.353	0.000
A57 Chancroid	0.646	0.353	0.000
A55 Chlamydial lymphogranuloma (venereum)	0.646	0.353	0.000
D69.2 Other nonthrombocytopenic purpura	0.645	0.355	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.644	0.356	0.000
E20.9 Hypoparathyroidism, unspecified	0.644	0.356	0.000
G23 Other degenerative diseases of basal ganglia	0.643	0.356	0.000
G55.0 Nerve root and plexus compressions in neoplastic disease	0.641	0.359	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.640	0.360	0.000
G45.2 Multiple and bilateral precerebral artery syndromes	0.638	0.362	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.638	0.362	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.637	0.363	0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.636	0.364	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.635	0.365	0.000
B37.0 Candidal stomatitis	0.635	0.365	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.366	0.634
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.366	0.634
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.366	0.634
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.366	0.634
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.366	0.634
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.366	0.634
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.366	0.634
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.366	0.634
M14 Arthropathies in other diseases classified elsewhere	0.000	0.369	0.631
G00.2 Streptococcal meningitis	0.628	0.371	0.000
L11 Other acantholytic disorders	0.627	0.373	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.627	0.373	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.627	0.373	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.626	0.374	0.000
M06.8 Other specified rheumatoid arthritis	0.000	0.374	0.625
D69.1 Qualitative platelet defects	0.625	0.375	0.000
G44.1 Vascular headache, not elsewhere classified	0.624	0.376	0.000
A63.8 Other specified predominantly sexually transmitted diseases	0.624	0.376	0.000
D83 Common variable immunodeficiency	0.623	0.377	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.377	0.623
D80 Immunodeficiency with predominantly antibody defects	0.623	0.377	0.000
L50.1 Idiopathic urticaria	0.623	0.377	0.000
G57 Mononeuropathies of lower limb	0.620	0.380	0.000
B30 Viral conjunctivitis	0.620	0.380	0.000
B50-B64 Protozoal diseases	0.619	0.381	0.000
B26 Mumps	0.619	0.381	0.000
E89.0 Postprocedural hypothyroidism	0.619	0.381	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.618	0.382	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.383	0.617
D59.0 Drug-induced autoimmune haemolytic anaemia	0.617	0.383	0.000
D55 Anaemia due to enzyme disorders	0.615	0.384	0.000
E61 Deficiency of other nutrient elements	0.614	0.385	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.000	0.389	0.611
E24 Cushing's syndrome	0.608	0.392	0.000
E73 Lactose intolerance	0.608	0.392	0.000
G44.2 Tension-type headache	0.607	0.393	0.000
B33 Other viral diseases, not elsewhere classified	0.607	0.393	0.000
E55.0 Rickets, active	0.606	0.394	0.000
E28 Ovarian dysfunction	0.606	0.394	0.000
E56 Other vitamin deficiencies	0.605	0.394	0.000
D73 Diseases of spleen	0.605	0.395	0.000
E63.9 Nutritional deficiency, unspecified	0.604	0.395	0.000
B25.8 Other cytomegaloviral diseases	0.604	0.396	0.000
D86.0 Sarcoidosis of lung	0.602	0.398	0.000
D67 Hereditary factor IX deficiency	0.601	0.399	0.000
D69.5 Secondary thrombocytopenia	0.600	0.400	0.000
A15-A19 Tuberculosis	0.600	0.400	0.000
A40.8 Other streptococcal septicaemia	0.599	0.401	0.000
E06 Thyroiditis	0.599	0.401	0.000
A86 Unspecified viral encephalitis	0.598	0.402	0.000
B01.2 Varicella pneumonia	0.598	0.402	0.000
D68.6 Other Thrombophilia	0.598	0.402	0.000
G44.3 Chronic posttraumatic headache	0.596	0.404	0.000
A40.3 Septicaemia due to Streptococcus pneumoniae	0.596	0.404	0.000
A41.2 Septicaemia due to unspecified staphylococcus	0.596	0.404	0.000
G45.1 Carotid artery syndrome (hemispheric)	0.595	0.405	0.000
B23.8 HIV disease resulting in other specified conditions	0.594	0.406	0.000
G57.8 Other mononeuropathies of lower limb	0.594	0.406	0.000
G00.1 Pneumococcal meningitis	0.590	0.410	0.000
B25.0 Cytomegaloviral pneumonitis	0.589	0.411	0.000
D59.8 Other acquired haemolytic anaemias	0.588	0.411	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.588	0.411	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.588	0.411	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.588	0.411	0.000
D59.3 Haemolytic-uraemic syndrome	0.588	0.411	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.588	0.411	0.000
D61.0 Constitutional aplastic anaemia	0.588	0.412	0.000
G45.0 Vertebro-basilar artery syndrome	0.588	0.412	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.585	0.415	0.000
E53.8 Deficiency of other specified B group vitamins	0.585	0.415	0.000
E58 Dietary calcium deficiency	0.585	0.415	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.585	0.415	0.000
E22.8 Other hyperfunction of pituitary gland	0.584	0.416	0.000
M11 Other crystal arthropathies	0.000	0.416	0.584
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.416	0.584
E34.8 Other specified endocrine disorders	0.583	0.417	0.000
G31.8 Other specified degenerative diseases of nervous system	0.582	0.418	0.000
D68.8 Other specified coagulation defects	0.582	0.418	0.000
G31.2 Degeneration of nervous system due to alcohol	0.581	0.419	0.000
B25.2 Cytomegaloviral pancreatitis	0.579	0.420	0.000
B25.1 Cytomegaloviral hepatitis	0.579	0.420	0.000
A60 Anogenital herpesviral [herpes simplex] infections	0.579	0.421	0.000
E07.1 Dyshormogenetic goitre	0.579	0.421	0.000
E07.0 Hypersecretion of calcitonin	0.579	0.421	0.000
D84.1 Defects in the complement system	0.579	0.421	0.000
A80 Acute poliomyelitis	0.579	0.421	0.000
D86.8 Sarcoidosis of other and combined sites	0.579	0.421	0.000
D89.1 Cryoglobulinaemia	0.579	0.421	0.000
E31.9 Polyglandular dysfunction, unspecified	0.576	0.424	0.000
E31.8 Other polyglandular dysfunction	0.576	0.424	0.000
E31.1 Polyglandular hyperfunction	0.576	0.424	0.000
B35 Dermatophytosis	0.575	0.425	0.000
A87 Viral meningitis	0.574	0.426	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.573	0.427	0.000
G24.9 Dystonia, unspecified	0.571	0.429	0.000
D89.3 Immune reconstitution syndrome	0.571	0.429	0.000
E34.5 Androgen resistance syndrome	0.569	0.431	0.000
E34.4 Constitutional tall stature	0.569	0.431	0.000
E34.3 Short stature, not elsewhere classified	0.569	0.431	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.569	0.431	0.000
E34.1 Other hypersecretion of intestinal hormones	0.569	0.431	0.000
D57 Sickle-cell disorders	0.569	0.431	0.000
E20.8 Other hypoparathyroidism	0.568	0.432	0.000
E20.1 Pseudohypoparathyroidism	0.568	0.432	0.000
E20.0 Idiopathic hypoparathyroidism	0.568	0.432	0.000
D74 Methaemoglobinaemia	0.567	0.432	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.567	0.432	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.567	0.432	0.000
L26 Exfoliative dermatitis	0.566	0.434	0.000
B34 Viral infection of unspecified site	0.565	0.435	0.000
L50.0 Allergic urticaria	0.565	0.435	0.000
D86.1 Sarcoidosis of lymph nodes	0.564	0.435	0.000
A41.9 Septicaemia, unspecified	0.564	0.436	0.000
E21.2 Other hyperparathyroidism	0.564	0.436	0.000
D56 Thalassaemia	0.563	0.437	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.562	0.438	0.000
G45.3 Amaurosis fugax	0.561	0.438	0.000
A42 Actinomycosis	0.561	0.439	0.000
L53.0 Toxic erythema	0.561	0.439	0.000
E51.9 Thiamine deficiency, unspecified	0.559	0.440	0.000
E51.8 Other manifestations of thiamine deficiency	0.559	0.440	0.000
E51.1 Beriberi	0.559	0.440	0.000
L54 Erythema in diseases classified elsewhere	0.559	0.441	0.000
B00.5 Herpesviral ocular disease	0.559	0.441	0.000
L14 Bullous disorders in diseases classified elsewhere	0.558	0.441	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.558	0.442	0.000
L28 Lichen simplex chronicus and prurigo	0.558	0.442	0.000
A44 Bartonellosis	0.557	0.443	0.000
A43 Nocardiosis	0.557	0.443	0.000
A37 Whooping cough	0.557	0.443	0.000
A36 Diphtheria	0.557	0.443	0.000
A32 Listeriosis	0.557	0.443	0.000
A30 Leprosy [Hansen's disease]	0.557	0.443	0.000
A38 Scarlet fever	0.557	0.443	0.000
A35 Other tetanus	0.557	0.443	0.000
A34 Obstetrical tetanus	0.557	0.443	0.000
A33 Tetanus neonatorum	0.557	0.443	0.000
A88 Other viral infections of central nervous system, not elsewhere classified	0.557	0.443	0.000
A85 Other viral encephalitis, not elsewhere classified	0.557	0.443	0.000
A84 Tick-borne viral encephalitis	0.557	0.443	0.000
A83 Mosquito-borne viral encephalitis	0.557	0.443	0.000
A82 Rabies	0.557	0.443	0.000
A91 Dengue haemorrhagic fever	0.557	0.443	0.000
A90 Dengue fever [classical dengue]	0.557	0.443	0.000
A89 Unspecified viral infection of central nervous system	0.557	0.443	0.000
D82.1 Di George's syndrome	0.555	0.445	0.000
L40-L45 Papulosquamous disorders	0.552	0.447	0.001
L10 Pemphigus	0.552	0.447	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.000	0.447	0.552
M05.88 Other seropositive rheumatoid arthritis (Other)	0.000	0.447	0.552
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.000	0.447	0.552
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.000	0.447	0.552
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.000	0.447	0.552
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.000	0.447	0.552
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.000	0.447	0.552
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.000	0.447	0.552
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.000	0.447	0.552
B20.6 HIV disease resulting in Pneumocystis carinii pneumonia	0.552	0.448	0.000
L23 Allergic contact dermatitis	0.552	0.448	0.000
A40.2 Septicaemia due to streptococcus, group D	0.552	0.448	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.551	0.449	0.000
D66 Hereditary factor VIII deficiency	0.549	0.451	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.549	0.451	0.000
L53.9 Erythematous condition, unspecified	0.549	0.451	0.000
G00.8 Other bacterial meningitis	0.546	0.454	0.000
G00.3 Staphylococcal meningitis	0.546	0.454	0.000
G00.0 Haemophilus meningitis	0.546	0.454	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.545	0.455	0.000
E04.9 Non-toxic goitre, unspecified	0.543	0.457	0.000
D72.9 Disorder of white blood cells, unspecified	0.543	0.457	0.000
D72.0 Genetic anomalies of leukocytes	0.543	0.457	0.000
G41.8 Other status epilepticus	0.543	0.457	0.000
G41.2 Complex partial status epilepticus	0.543	0.457	0.000
G41.1 Petit mal status epilepticus	0.543	0.457	0.000
A81 Atypical virus infections of central nervous system	0.542	0.457	0.000
L25 Unspecified contact dermatitis	0.542	0.458	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.541	0.459	0.000
L51 Erythema multiforme	0.541	0.459	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.540	0.460	0.000
E88 Other metabolic disorders	0.540	0.460	0.000
L13.9 Bullous disorder, unspecified	0.538	0.462	0.000
L13.8 Other specified bullous disorders	0.538	0.462	0.000
L13.1 Subcorneal pustular dermatitis	0.538	0.462	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.538	0.462	0.000
A41.3 Septicaemia due to Haemophilus influenzae	0.538	0.462	0.000
Q00-Q07 Congenital malformations of the nervous system	0.537	0.463	0.000
B15-B19 Viral hepatitis	0.536	0.464	0.000
E73.9 Lactose intolerance, unspecified	0.536	0.464	0.000
B01.1 Varicella encephalitis	0.533	0.467	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations