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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3131036
log Bayes Factor = 180.885
Chromosome 6   position 30,728,290  (GRCh37) Explore rs3131036 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
K70-K77 Diseases of liver
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
I74 Arterial embolism and thrombosis
0.999 0.001 0.000
K90 Intestinal malabsorption
0.999 0.001 0.000
E20-E35 Disorders of other endocrine glands
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
K75 Other inflammatory liver diseases
0.998 0.002 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.998 0.002 0.000
K75.4 Autoimmune hepatitis
0.998 0.002 0.000
Chapter I Certain infectious and parasitic diseases
0.997 0.003 0.000
D60-D64 Aplastic and other anaemias
0.997 0.003 0.000
N00-N08 Glomerular diseases
0.997 0.003 0.000
Chapter XI Diseases of the digestive system
0.997 0.003 0.000
K90-K93 Other diseases of the digestive system
0.996 0.004 0.000
D80-D89 Certain disorders involving the immune mechanism
0.996 0.004 0.000
Chapter XIV Diseases of the genitourinary system
0.995 0.005 0.000
E27 Other disorders of adrenal gland
0.995 0.005 0.000
Chapter VII Diseases of the eye and adnexa
0.993 0.007 0.000
N04 Nephrotic syndrome
0.992 0.008 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.991 0.009 0.000
M35.0 Sicca syndrome [Sjogren]
0.990 0.010 0.000
D64 Other anaemias
0.990 0.010 0.000
D86 Sarcoidosis
0.990 0.010 0.000
H30-H36 Disorders of choroid and retina
0.990 0.010 0.000
I71 Aortic aneurysm and dissection
0.990 0.010 0.000
B35-B49 Mycoses
0.989 0.011 0.000
E27.1 Primary adrenocortical insufficiency
0.988 0.012 0.000
H36 Retinal disorders in diseases classified elsewhere
0.987 0.013 0.000
E50-E64 Other nutritional deficiencies
0.986 0.014 0.000
K72 Hepatic failure, not elsewhere classified
0.986 0.014 0.000
H36.0 Diabetic retinopathy
0.986 0.014 0.000
D64.9 Anaemia, unspecified
0.985 0.015 0.000
B15-B19 Viral hepatitis
0.984 0.016 0.000
I73 Other peripheral vascular diseases
0.984 0.016 0.000
N04.9 Unspecified
0.984 0.016 0.000
E14 Unspecified diabetes mellitus
0.983 0.017 0.000
N05 Unspecified nephritic syndrome
0.982 0.018 0.000
R31 Unspecified haematuria
0.000 0.020 0.980
L97 Ulcer of lower limb, not elsewhere classified
0.979 0.021 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.978 0.022 0.000
E10.2 With renal complications
0.977 0.023 0.000
N40 Hyperplasia of prostate
0.000 0.023 0.977
N17-N19 Renal failure
0.975 0.025 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.975 0.025 0.000
I10-I15 Hypertensive diseases
0.974 0.026 0.000
B37 Candidiasis
0.973 0.027 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.972 0.028 0.000
D86.9 Sarcoidosis, unspecified
0.972 0.028 0.000
E53 Deficiency of other B group vitamins
0.972 0.028 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.972 0.028 0.000
K74 Fibrosis and cirrhosis of liver
0.971 0.029 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.971 0.029 0.000
E10.1 With ketoacidosis
0.970 0.030 0.000
I12 Hypertensive renal disease
0.968 0.032 0.000
B37.8 Candidiasis of other sites
0.967 0.033 0.000
M35 Other systemic involvement of connective tissue
0.966 0.034 0.000
G35 Multiple sclerosis
0.964 0.036 0.000
E53.8 Deficiency of other specified B group vitamins
0.962 0.038 0.000
D61 Other aplastic anaemias
0.962 0.038 0.000
H34 Retinal vascular occlusions
0.962 0.038 0.000
E14.3 With ophthalmic complications
0.961 0.039 0.000
L10-L14 Bullous disorders
0.961 0.039 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.961 0.039 0.000
Chapter VI Diseases of the nervous system
0.961 0.039 0.000
K73 Chronic hepatitis, not elsewhere classified
0.957 0.043 0.000
E16 Other disorders of pancreatic internal secretion
0.957 0.043 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.956 0.044 0.000
M20-M25 Other joint disorders
0.955 0.045 0.000
K72.0 Acute and subacute hepatic failure
0.955 0.045 0.000
N18 Chronic renal failure
0.955 0.045 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.953 0.047 0.000
Q50-Q56 Congenital malformations of genital organs
0.952 0.048 0.000
B18 Chronic viral hepatitis
0.949 0.051 0.000
H43-H45 Disorders of vitreous body and globe
0.949 0.051 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.948 0.052 0.000
L94 Other localised connective tissue disorders
0.948 0.052 0.000
E10.4 With neurological complications
0.945 0.055 0.000
I73.0 Raynaud's syndrome
0.943 0.057 0.000
I12.9 Hypertensive renal disease without renal failure
0.941 0.059 0.000
E06 Thyroiditis
0.934 0.066 0.000
Q51 Congenital malformations of uterus and cervix
0.934 0.066 0.000
H34.8 Other retinal vascular occlusions
0.934 0.066 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.933 0.067 0.000
B44 Aspergillosis
0.932 0.068 0.000
B18.2 Chronic viral hepatitis C
0.930 0.070 0.000
I12.0 Hypertensive renal disease with renal failure
0.929 0.071 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.929 0.071 0.000
E16.2 Hypoglycaemia, unspecified
0.929 0.071 0.000
N10-N16 Renal tubulo-interstitial diseases
0.923 0.077 0.000
B25-B34 Other viral diseases
0.920 0.080 0.000
N18.0 End-stage renal disease
0.919 0.081 0.000
H43 Disorders of vitreous body
0.918 0.082 0.000
N40-N51 Diseases of male genital organs
0.000 0.083 0.917
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.915 0.085 0.000
D61.9 Aplastic anaemia, unspecified
0.915 0.085 0.000
E11 Non-insulin-dependent diabetes mellitus
0.913 0.087 0.000
D86.0 Sarcoidosis of lung
0.909 0.091 0.000
L13 Other bullous disorders
0.909 0.091 0.000
L50-L54 Urticaria and erythema
0.908 0.092 0.000
N11 Chronic tubulo-interstitial nephritis
0.907 0.093 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.097 0.903
E03.8 Other specified hypothyroidism
0.901 0.099 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.897 0.103 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.896 0.104 0.000
K73.9 Chronic hepatitis, unspecified
0.895 0.105 0.000
Q51.3 Bicornate uterus
0.895 0.105 0.000
K74.3 Primary biliary cirrhosis
0.895 0.105 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.892 0.108 0.000
E13 Other specified diabetes mellitus
0.891 0.109 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.886 0.114 0.000
N05.2 Diffuse membranous glomerulonephritis
0.881 0.119 0.000
E06.3 Autoimmune thyroiditis
0.879 0.121 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.879 0.121 0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified
0.878 0.122 0.000
M32 Systemic lupus erythematosus
0.875 0.125 0.000
E10.5 With peripheral circulatory complications
0.874 0.126 0.000
B16 Acute hepatitis B
0.873 0.127 0.000
K72.9 Hepatic failure, unspecified
0.872 0.128 0.000
L13.0 Dermatitis herpetiformis
0.872 0.128 0.000
K90.9 Intestinal malabsorption, unspecified
0.870 0.130 0.000
L94.2 Calcinosis cutis
0.870 0.130 0.000
E11.0 With coma
0.868 0.132 0.000
H43.1 Vitreous haemorrhage
0.867 0.133 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.864 0.136 0.000
K75.8 Other specified inflammatory liver diseases
0.862 0.138 0.000
B50-B64 Protozoal diseases
0.862 0.138 0.000
M22 Disorders of patella
0.861 0.139 0.000
N05.8 Other
0.861 0.139 0.000
B25 Cytomegaloviral disease
0.858 0.142 0.000
I77 Other disorders of arteries and arterioles
0.854 0.146 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.854 0.146 0.000
M60-M63 Disorders of muscles
0.854 0.146 0.000
N18.9 Chronic renal failure, unspecified
0.854 0.146 0.000
E23 Hypofunction and other disorders of pituitary gland
0.853 0.147 0.000
E14.8 With unspecified complications
0.852 0.148 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.852 0.148 0.000
L94.0 Localised scleroderma [morphea]
0.851 0.149 0.000
E14.1 With ketoacidosis
0.851 0.149 0.000
G30-G32 Other degenerative diseases of the nervous system
0.850 0.150 0.000
N05.1 Focal and segmental glomerular lesions
0.850 0.150 0.000
B44.9 Aspergillosis, unspecified
0.843 0.157 0.000
K74.0 Hepatic fibrosis
0.843 0.157 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.839 0.161 0.000
N04.1 Focal and segmental glomerular lesions
0.839 0.161 0.000
E11.5 With peripheral circulatory complications
0.833 0.167 0.000
B37.0 Candidal stomatitis
0.833 0.167 0.000
Q53 Undescended testicle
0.832 0.168 0.000
K76 Other diseases of liver
0.830 0.170 0.000
E29 Testicular dysfunction
0.829 0.171 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.828 0.172 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.827 0.173 0.000
B17 Other acute viral hepatitis
0.824 0.176 0.000
I73.9 Peripheral vascular disease, unspecified
0.823 0.177 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.822 0.178 0.000
E24 Cushing's syndrome
0.820 0.180 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.819 0.181 0.000
N04.2 Diffuse membranous glomerulonephritis
0.818 0.182 0.000
L52 Erythema nodosum
0.815 0.185 0.000
D61.1 Drug-induced aplastic anaemia
0.814 0.186 0.000
M65-M68 Disorders of synovium and tendon
0.813 0.187 0.000
E58 Dietary calcium deficiency
0.813 0.187 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.813 0.187 0.000
I73.8 Other specified peripheral vascular diseases
0.813 0.187 0.000
N10 Acute tubulo-interstitial nephritis
0.812 0.188 0.000
N18.5 Chronic kidney disease, stage 5
0.811 0.189 0.000
B44.1 Other pulmonary aspergillosis
0.810 0.190 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.810 0.190 0.000
L93 Lupus erythematosus
0.810 0.190 0.000
L11 Other acantholytic disorders
0.809 0.191 0.000
Q40 Other congenital malformations of upper alimentary tract
0.809 0.191 0.000
L40-L45 Papulosquamous disorders
0.808 0.192 0.000
L89 Decubitus ulcer
0.807 0.193 0.000
I77.1 Stricture of artery
0.806 0.194 0.000
D83 Common variable immunodeficiency
0.805 0.195 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.805 0.195 0.000
E25 Adrenogenital disorders
0.803 0.197 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.803 0.197 0.000
Q45 Other congenital malformations of digestive system
0.800 0.200 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.800 0.200 0.000
E14.2 Withrenal complications
0.798 0.202 0.000
A30-A49 Other bacterial diseases
0.798 0.202 0.000
G70-G73 Diseases of myoneural junction and muscle
0.797 0.203 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.795 0.205 0.000
Q51.2 Other doubling of uterus
0.795 0.205 0.000
E11.1 With ketoacidosis
0.794 0.206 0.000
H06.2 Dysthyroid exophthalmos
0.794 0.206 0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma
0.793 0.207 0.000
N00 Acute nephritic syndrome
0.791 0.209 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.788 0.212 0.000
I11 Hypertensive heart disease
0.783 0.217 0.000
A41 Other septicaemia
0.783 0.217 0.000
D50-D53 Nutritional anaemias
0.783 0.217 0.000
N18.8 Other chronic renal failure
0.782 0.218 0.000
E13.9 Without complications
0.781 0.219 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.781 0.219 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.781 0.219 0.000
N05.9 Unspecified
0.781 0.219 0.000
K74.6 Other and unspecified cirrhosis of liver
0.780 0.220 0.000
K76.9 Liver disease, unspecified
0.780 0.220 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.779 0.221 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.779 0.221 0.000
I70 Atherosclerosis
0.779 0.221 0.000
E51 Thiamine deficiency
0.778 0.222 0.000
D55-D59 Haemolytic anaemias
0.777 0.223 0.000
H34.2 Other retinal artery occlusions
0.776 0.224 0.000
E21.0 Primary hyperparathyroidism
0.776 0.224 0.000
A41.9 Septicaemia, unspecified
0.775 0.225 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.772 0.228 0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis
0.772 0.228 0.000
E10.7 With multiple complications
0.771 0.228 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.771 0.229 0.000
M24 Other specific joint derangements
0.770 0.230 0.000
L80 Vitiligo
0.769 0.231 0.000
B25.9 Cytomegaloviral disease, unspecified
0.769 0.231 0.000
M66 Spontaneous rupture of synovium and tendon
0.769 0.231 0.000
B50 Plasmodium falciparum malaria
0.769 0.231 0.000
M22.3 Other derangements of patella
0.768 0.232 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.768 0.232 0.000
H43.8 Other disorders of vitreous body
0.768 0.232 0.000
K72.1 Chronic hepatic failure
0.767 0.233 0.000
I05-I09 Chronic rheumatic heart diseases
0.766 0.234 0.000
Q51.8 Other congenital malformations of uterus and cervix
0.765 0.235 0.000
E20 Hypoparathyroidism
0.764 0.236 0.000
M33 Dermatopolymyositis
0.764 0.236 0.000
L43 Lichen planus
0.764 0.236 0.000
N19 Unspecified renal failure
0.764 0.236 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.763 0.236 0.000
I74.5 Embolism and thrombosis of iliac artery
0.763 0.237 0.000
M35.1 Other overlap syndromes
0.762 0.238 0.000
I77.6 Arteritis, unspecified
0.761 0.239 0.000
E31 Polyglandular dysfunction
0.761 0.239 0.000
N41 Inflammatory diseases of prostate
0.000 0.239 0.761
I73.1 Thromboangiitis obliterans [Buerger]
0.759 0.241 0.000
K76.6 Portal hypertension
0.757 0.243 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.756 0.244 0.000
L50 Urticaria
0.756 0.244 0.000
H43.3 Other vitreous opacities
0.751 0.249 0.000
K70 Alcoholic liver disease
0.751 0.249 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.750 0.250 0.000
E11.3 With ophthalmic complications
0.749 0.251 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.748 0.252 0.000
A15-A19 Tuberculosis
0.748 0.252 0.000
D86.3 Sarcoidosis of skin
0.747 0.253 0.000
Q43 Other congenital malformations of intestine
0.746 0.254 0.000
N05.7 Diffuse crescentic glomerulonephritis
0.745 0.255 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.744 0.256 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.744 0.256 0.000
H30 Chorioretinal inflammation
0.744 0.256 0.000
M22.8 Other disorders of patella
0.744 0.256 0.000
H05 Disorders of orbit
0.743 0.257 0.000
B34 Viral infection of unspecified site
0.740 0.260 0.000
K74.5 Biliary cirrhosis, unspecified
0.740 0.260 0.000
N44 Torsion of testis
0.000 0.262 0.737
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.737 0.263 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.736 0.264 0.000
D86.8 Sarcoidosis of other and combined sites
0.736 0.264 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.735 0.265 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.735 0.265 0.000
G36 Other acute disseminated demyelination
0.735 0.265 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.734 0.266 0.000
L10 Pemphigus
0.733 0.267 0.000
E27.9 Disorder of adrenal gland, unspecified
0.733 0.267 0.000
B37.9 Candidiasis, unspecified
0.731 0.269 0.000
I74.8 Embolism and thrombosis of other arteries
0.731 0.269 0.000
L53 Other erythematous conditions
0.730 0.270 0.000
D82 Immunodeficiency associated with other major defects
0.730 0.270 0.000
M62 Other disorders of muscle
0.730 0.270 0.000
I00-I02 Acute rheumatic fever
0.729 0.271 0.000
N17 Acute renal failure
0.729 0.271 0.000
H34.1 Central retinal artery occlusion
0.728 0.272 0.000
G30 Alzheimer's disease
0.726 0.274 0.000
L92.0 Granuloma annulare
0.725 0.275 0.000
E22 Hyperfunction of pituitary gland
0.725 0.275 0.000
Q53.1 Undescended testicle, unilateral
0.725 0.275 0.000
B65-B83 Helminthiases
0.723 0.277 0.000
L12 Pemphigoid
0.722 0.278 0.000
M70-M79 Other soft tissue disorders
0.721 0.279 0.000
H46 Optic neuritis
0.720 0.280 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.719 0.281 0.000
A80-A89 Viral infections of the central nervous system
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
K77 Liver disorders in diseases classified elsewhere
0.717 0.283 0.000
M66.0 Rupture of popliteal cyst
0.717 0.283 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.717 0.283 0.000
K90.3 Pancreatic steatorrhoea
0.716 0.283 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.716 0.283 0.000
K90.1 Tropical sprue
0.716 0.283 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.716 0.283 0.000
E32 Diseases of thymus
0.716 0.283 0.000
E30 Disorders of puberty, not elsewhere classified
0.716 0.283 0.000
L94.9 Localised connective tissue disorder, unspecified
0.716 0.284 0.000
M60 Myositis
0.716 0.284 0.000
K75.2 Nonspecific reactive hepatitis
0.716 0.284 0.000
K75.1 Phlebitis of portal vein
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.715 0.285 0.000
A75-A79 Rickettsioses
0.715 0.285 0.000
A70-A74 Other diseases caused by chlamydiae
0.715 0.285 0.000
A20-A28 Certain zoonotic bacterial diseases
0.715 0.285 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.715 0.285 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.715 0.285 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.715 0.285 0.000
N06 Isolated proteinuria with specified morphological lesion
0.715 0.285 0.000
N01 Rapidly progressive nephritic syndrome
0.715 0.285 0.000
N41.1 Chronic prostatitis
0.000 0.285 0.715
L94.8 Other specified localised connective tissue disorders
0.714 0.286 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.714 0.286 0.000
H47.2 Optic atrophy
0.714 0.286 0.000
D81 Combined immunodeficiencies
0.714 0.286 0.000
E27.5 Adrenomedullary hyperfunction
0.713 0.287 0.000
E27.0 Other adrenocortical overactivity
0.713 0.287 0.000
N04.8 Other
0.711 0.288 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.711 0.288 0.000
N04.6 Dense deposit disease
0.711 0.288 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.711 0.288 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.711 0.288 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.711 0.288 0.000
N11.1 Chronic obstructive pyelonephritis
0.711 0.289 0.000
E13.3 With ophthalmic complications
0.710 0.290 0.000
D84 Other immunodeficiencies
0.710 0.290 0.000
D64.4 Congenital dyserythropoietic anaemia
0.710 0.290 0.000
D64.3 Other sideroblastic anaemias
0.710 0.290 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.710 0.290 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.710 0.290 0.000
D64.0 Hereditary sideroblastic anaemia
0.710 0.290 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.710 0.290 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.710 0.290 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.709 0.290 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.709 0.290 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.709 0.290 0.000
B48 Other mycoses, not elsewhere classified
0.709 0.291 0.000
B47 Mycetoma
0.709 0.291 0.000
B46 Zygomycosis
0.709 0.291 0.000
B45 Cryptococcosis
0.709 0.291 0.000
B43 Chromomycosis and phaeomycotic abscess
0.709 0.291 0.000
B42 Sporotrichosis
0.709 0.291 0.000
B41 Paracoccidioidomycosis
0.709 0.291 0.000
B40 Blastomycosis
0.709 0.291 0.000
B39 Histoplasmosis
0.709 0.291 0.000
B38 Coccidioidomycosis
0.709 0.291 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.708 0.292 0.000
E29.1 Testicular hypofunction
0.708 0.292 0.000
Q00-Q07 Congenital malformations of the nervous system
0.707 0.292 0.000
B25.8 Other cytomegaloviral diseases
0.707 0.293 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.707 0.293 0.000
E63 Other nutritional deficiencies
0.707 0.293 0.000
E56 Other vitamin deficiencies
0.707 0.293 0.000
E50 Vitamin A deficiency
0.707 0.293 0.000
E60 Dietary zinc deficiency
0.707 0.293 0.000
E59 Dietary selenium deficiency
0.707 0.293 0.000
E54 Ascorbic acid deficiency
0.707 0.293 0.000
E52 Niacin deficiency [pellagra]
0.707 0.293 0.000
K71 Toxic liver disease
0.707 0.293 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.707 0.293 0.000
B18.9 Chronic viral hepatitis, unspecified
0.706 0.294 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.706 0.294 0.000
E14.7 With multiple complications
0.705 0.295 0.000
E14.0 With coma
0.705 0.295 0.000
N05.6 Dense deposit disease
0.704 0.296 0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.704 0.296 0.000
N05.0 Minor glomerular abnormality
0.704 0.296 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.704 0.296 0.000
K90.8 Other intestinal malabsorption
0.703 0.297 0.000
I07 Rheumatic tricuspid valve diseases
0.703 0.297 0.000
E06.5 Other chronic thyroiditis
0.703 0.297 0.000
L43.9 Lichen planus, unspecified
0.703 0.297 0.000
E14.4 With neurological complications
0.702 0.298 0.000
B50.9 Plasmodium falciparum malaria, unspecified
0.702 0.298 0.000
D86.1 Sarcoidosis of lymph nodes
0.701 0.298 0.000
G72 Other myopathies
0.701 0.299 0.000
L87 Transepidermal elimination disorders
0.701 0.299 0.000
L86 Keratoderma in diseases classified elsewhere
0.701 0.299 0.000
E15 Nondiabetic hypoglycaemic coma
0.699 0.301 0.000
G54 Nerve root and plexus disorders
0.698 0.302 0.000
E11.6 With other specified complications
0.698 0.302 0.000
I13 Hypertensive heart and renal disease
0.698 0.302 0.000
B37.6 Candidal endocarditis
0.698 0.302 0.000
B37.5 Candidal meningitis
0.698 0.302 0.000
I79.1 Aortitis in diseases classified elsewhere
0.697 0.303 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.697 0.303 0.000
E53.1 Pyridoxine deficiency
0.697 0.303 0.000
E53.0 Riboflavin deficiency
0.697 0.303 0.000
D61.0 Constitutional aplastic anaemia
0.697 0.303 0.000
Q35-Q37 Cleft lip and cleft palate
0.697 0.303 0.000
K74.4 Secondary biliary cirrhosis
0.696 0.304 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.696 0.304 0.000
K74.1 Hepatic sclerosis
0.696 0.304 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.695 0.305 0.000
E14.6 With other specified complications
0.695 0.305 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.694 0.306 0.000
E10.8 With unspecified complications
0.694 0.306 0.000
M35.7 Hypermobility syndrome
0.694 0.306 0.000
N18.1 Chronic kidney disease, stage 1
0.694 0.306 0.000
B15 Acute hepatitis A
0.694 0.306 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.692 0.308 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.692 0.308 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.692 0.308 0.000
M35.5 Multifocal fibrosclerosis
0.692 0.308 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.692 0.308 0.000
M24.5 Contracture of joint
0.690 0.310 0.000
D61.8 Other specified aplastic anaemias
0.690 0.310 0.000
D61.3 Idiopathic aplastic anaemia
0.690 0.310 0.000
D61.2 Aplastic anaemia due to other external agents
0.690 0.310 0.000
H34.0 Transient retinal artery occlusion
0.690 0.310 0.000
D64.8 Other specified anaemias
0.690 0.310 0.000
L14 Bullous disorders in diseases classified elsewhere
0.689 0.311 0.000
E23.6 Other disorders of pituitary gland
0.687 0.313 0.000
E53.9 Vitamin B deficiency, unspecified
0.687 0.313 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.687 0.313 0.000
B33 Other viral diseases, not elsewhere classified
0.687 0.313 0.000
N45 Orchitis and epididymitis
0.000 0.313 0.686
E23.7 Disorder of pituitary gland, unspecified
0.686 0.314 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.686 0.314 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.686 0.314 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.686 0.314 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.686 0.314 0.000
E16.4 Abnormal secretion of gastrin
0.686 0.314 0.000
E16.3 Increased secretion of glucagon
0.686 0.314 0.000
K70.0 Alcoholic fatty liver
0.686 0.314 0.000
H43.2 Crystalline deposits in vitreous body
0.685 0.314 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.685 0.315 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.685 0.315 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.685 0.315 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.685 0.315 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.685 0.315 0.000
E24.0 Pituitary-dependent Cushing's disease
0.683 0.317 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.682 0.318 0.000
B18.8 Other chronic viral hepatitis
0.680 0.320 0.000
B18.0 Chronic viral hepatitis B with delta-agent
0.680 0.320 0.000
E16.1 Other hypoglycaemia
0.680 0.320 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.680 0.320 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.680 0.320 0.000
L94.6 Ainhum
0.680 0.320 0.000
L94.5 Poikiloderma vasculare atrophicans
0.680 0.320 0.000
L94.4 Gottron's papules
0.680 0.320 0.000
L94.3 Sclerodactyly
0.680 0.320 0.000
L94.1 Linear scleroderma
0.680 0.320 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.679 0.321 0.000
M66.06 Rupture of popliteal cyst-Lower leg
0.679 0.321 0.000
B36 Other superficial mycoses
0.679 0.321 0.000
E40-E46 Malnutrition
0.678 0.321 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.678 0.322 0.000
L93.1 Subacute cutaneous lupus erythematosus
0.678 0.322 0.000
N04.0 Minor glomerular abnormality
0.678 0.322 0.000
B37.2 Candidiasis of skin and nail
0.677 0.322 0.000
Q40.2 Other specified congenital malformations of stomach
0.677 0.323 0.000
L11.0 Acquired keratosis follicularis
0.677 0.323 0.000
M34 Systemic sclerosis
0.676 0.324 0.000
M22.0 Recurrent dislocation of patella
0.676 0.324 0.000
E21.3 Hyperparathyroidism, unspecified
0.673 0.327 0.000
E06.9 Thyroiditis, unspecified
0.673 0.327 0.000
Q45.8 Other specified congenital malformations of digestive system
0.672 0.328 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.671 0.329 0.000
H44 Disorders of globe
0.670 0.330 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.670 0.330 0.000
H10-H13 Disorders of conjunctiva
0.670 0.330 0.000
E06.4 Drug-induced thyroiditis
0.670 0.330 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.670 0.330 0.000
E06.1 Subacute thyroiditis
0.670 0.330 0.000
E06.0 Acute thyroiditis
0.670 0.330 0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified
0.669 0.330 0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts
0.669 0.330 0.000
Q51.6 Embryonic cyst of cervix
0.669 0.330 0.000
Q51.5 Agenesis and aplasia of cervix
0.669 0.330 0.000
Q51.4 Unicornate uterus
0.669 0.330 0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina
0.669 0.330 0.000
Q51.0 Agenesis and aplasia of uterus
0.669 0.330 0.000
G56 Mononeuropathies of upper limb
0.669 0.331 0.000
D83.9 Common variable immunodeficiency, unspecified
0.669 0.331 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.669 0.331 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.669 0.331 0.000
B44.8 Other forms of aspergillosis
0.668 0.332 0.000
B44.7 Disseminated aspergillosis
0.668 0.332 0.000
B44.2 Tonsillar aspergillosis
0.668 0.332 0.000
B44.0 Invasive pulmonary aspergillosis
0.668 0.332 0.000
N03 Chronic nephritic syndrome
0.668 0.332 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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