TreeWAS – Variant ID: rs34245511

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C67.9 Bladder, unspecified	0.135	0.865	0.000
C67 Malignant neoplasm of bladder	0.131	0.869	0.000
C67.4 Posterior wall of bladder	0.127	0.873	0.000
C67.6 Ureteric orifice	0.117	0.883	0.000
C67.5 Bladder neck	0.104	0.896	0.000
C67.1 Dome of bladder	0.102	0.898	0.000
C67.2 Lateral wall of bladder	0.096	0.904	0.000
C67.7 Urachus	0.094	0.906	0.000
C67.0 Trigone of bladder	0.093	0.907	0.000
C67.8 Overlapping lesion of bladder	0.085	0.915	0.000
C67.3 Anterior wall of bladder	0.082	0.918	0.000
C64-C68 Malignant neoplasms of urinary tract	0.068	0.932	0.000
C65 Malignant neoplasm of renal pelvis	0.061	0.939	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.050	0.950	0.000
C66 Malignant neoplasm of ureter	0.049	0.951	0.000
L30.9 Dermatitis, unspecified	0.042	0.958	0.000
D12.5 Sigmoid colon	0.039	0.961	0.000
C68.0 Urethra	0.037	0.963	0.000
C68.9 Urinary organ, unspecified	0.036	0.963	0.000
C68.8 Overlapping lesion of urinary organs	0.036	0.964	0.000
C68.1 Paraurethral glands	0.036	0.964	0.000
D12.2 Ascending colon	0.031	0.969	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.030	0.970	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.029	0.971	0.000
D12.7 Rectosigmoid junction	0.029	0.971	0.000
F31 Bipolar affective disorder	0.028	0.972	0.000
F31.7 Bipolar affective disorder, currently in remission	0.025	0.975	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.025	0.975	0.000
D12.0 Caecum	0.025	0.975	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.024	0.976	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.024	0.976	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.023	0.977	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.023	0.977	0.000
F31.8 Other bipolar affective disorders	0.023	0.977	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.023	0.977	0.000
L30 Other dermatitis	0.022	0.978	0.000
D12.3 Transverse colon	0.022	0.978	0.000
D12.1 Appendix	0.021	0.979	0.000
Z99.1 Dependence on respirator	0.020	0.980	0.000
D12.8 Rectum	0.020	0.980	0.000
F31.9 Bipolar affective disorder, unspecified	0.020	0.980	0.000
R60.0 Localised oedema	0.000	0.981	0.019
L30.4 Erythema intertrigo	0.018	0.982	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.017	0.982	0.000
S82.60 Fracture of lateral malleolus (closed)	0.017	0.983	0.000
M25.51 Pain in joint (Shoulder region)	0.017	0.983	0.000
L30.5 Pityriasis alba	0.016	0.984	0.000
L30.2 Cutaneous autosensitisation	0.016	0.984	0.000
L30.0 Nummular dermatitis	0.016	0.984	0.000
L30.1 Dyshidrosis [pompholyx]	0.016	0.984	0.000
L30.8 Other specified dermatitis	0.016	0.984	0.000
R60 Oedema, not elsewhere classified	0.000	0.984	0.016
R60.9 Oedema, unspecified	0.000	0.984	0.016
L30.3 Infective dermatitis	0.014	0.986	0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.000	0.986	0.014
R60.1 Generalised oedema	0.000	0.988	0.012
D12.4 Descending colon	0.010	0.990	0.000
D12.6 Colon, unspecified	0.009	0.991	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.008	0.992	0.000
D12.9 Anus and anal canal	0.008	0.992	0.001
D23.6 Skin of upper limb, including shoulder	0.000	0.992	0.008
L29.2 Pruritus vulvae	0.008	0.992	0.000
S82.6 Fracture of lateral malleolus	0.007	0.993	0.000
M88.9 Paget's disease of bone, unspecified	0.007	0.993	0.000
G47.3 Sleep apnoea	0.007	0.993	0.000
C18.2 Ascending colon	0.007	0.993	0.000
N97.1 Female infertility of tubal origin	0.007	0.993	0.000
W19.9 Unspecified place	0.000	0.994	0.006
N45 Orchitis and epididymitis	0.000	0.994	0.006
I84.3 External thrombosed haemorrhoids	0.006	0.994	0.000
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.006	0.994	0.000
L20-L30 Dermatitis and eczema	0.006	0.994	0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.006	0.994	0.000
N32.9 Bladder disorder, unspecified	0.006	0.994	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.006	0.994	0.000
R01.1 Cardiac murmur, unspecified	0.006	0.994	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.000	0.994	0.006
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.994	0.006
L29 Pruritus	0.006	0.994	0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.006	0.994	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.994	0.006
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.994	0.005
M88.98 Paget's disease of bone, unspecified (Other)	0.005	0.995	0.000
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.005	0.995	0.000
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.005	0.995	0.000
M88.94 Paget's disease of bone, unspecified (Hand)	0.005	0.995	0.000
M88.93 Paget's disease of bone, unspecified (Forearm)	0.005	0.995	0.000
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.005	0.995	0.000
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.005	0.995	0.000
L28 Lichen simplex chronicus and prurigo	0.005	0.995	0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess	0.000	0.995	0.005
L25 Unspecified contact dermatitis	0.005	0.995	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.995	0.005
S82.61 Fracture of lateral malleolus (open)	0.005	0.995	0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.005	0.995	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.995	0.005
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.005	0.995	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.995	0.005
L29.8 Other pruritus	0.005	0.995	0.000
H50.0 Convergent concomitant strabismus	0.000	0.995	0.005
L28.0 Lichen simplex chronicus	0.005	0.995	0.000
L24 Irritant contact dermatitis	0.004	0.995	0.000
L26 Exfoliative dermatitis	0.004	0.995	0.000
L22 Diaper [napkin] dermatitis	0.004	0.995	0.000
S22.40 Multiple fractures of ribs (closed)	0.000	0.995	0.005
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.996	0.004
S22.1 Multiple fractures of thoracic spine	0.000	0.996	0.004
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.004	0.996	0.000
W19.2 School, other institution and public administrative area	0.000	0.996	0.004
Z97.5 Presence of (intra-uterine) contraceptive device	0.000	0.996	0.004
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.996	0.004
T25.2 Burn of second degree of ankle and foot	0.004	0.996	0.000
L29.1 Pruritus scroti	0.004	0.996	0.000
G47 Sleep disorders	0.004	0.996	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.004	0.996	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.996	0.004
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.996	0.004
S22.4 Multiple fractures of ribs	0.000	0.996	0.004
L25.9 Unspecified contact dermatitis, unspecified cause	0.004	0.996	0.000
L21 Seborrhoeic dermatitis	0.004	0.996	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.004	0.996	0.000
S22.30 Fracture of rib (closed)	0.000	0.996	0.004
L28.2 Other prurigo	0.004	0.996	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.996	0.004
L28.1 Prurigo nodularis	0.004	0.996	0.000
S22.3 Fracture of rib	0.000	0.996	0.004
C92.0 Acute myeloid leukaemia	0.000	0.996	0.004
F30-F39 Mood [affective] disorders	0.004	0.996	0.000
M24.07 Loose body in joint (Ankle and foot)	0.000	0.996	0.004
L25.8 Unspecified contact dermatitis due to other agents	0.004	0.996	0.000
L25.5 Unspecified contact dermatitis due to plants, except food	0.004	0.996	0.000
L25.4 Unspecified contact dermatitis due to food in contact with the skin	0.004	0.996	0.000
L25.3 Unspecified contact dermatitis due to other chemical products	0.004	0.996	0.000
L25.2 Unspecified contact dermatitis due to dyes	0.004	0.996	0.000
L25.1 Unspecified contact dermatitis due to drugs in contact with the skin	0.004	0.996	0.000
L25.0 Unspecified contact dermatitis due to cosmetics	0.004	0.996	0.000
S22.2 Fracture of sternum	0.000	0.996	0.004
L20 Atopic dermatitis	0.003	0.996	0.001
H50.5 Heterophoria	0.000	0.996	0.004
L29.3 Anogenital pruritus, unspecified	0.004	0.996	0.000
M84 Disorders of continuity of bone	0.000	0.996	0.004
S22.20 Fracture of sternum (closed)	0.000	0.996	0.004
G47.9 Sleep disorder, unspecified	0.004	0.996	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.004	0.996	0.000
M88 Paget's disease of bone [osteitis deformans]	0.004	0.996	0.000
L23 Allergic contact dermatitis	0.003	0.996	0.000
N97 Female infertility	0.004	0.996	0.000
I67.1 Cerebral aneurysm, nonruptured	0.000	0.996	0.004
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.004	0.996	0.000
W19 Unspecified fall	0.000	0.996	0.004
L24.9 Irritant contact dermatitis, unspecified cause	0.003	0.996	0.000
L24.8 Irritant contact dermatitis due to other agents	0.003	0.996	0.000
L24.7 Irritant contact dermatitis due to plants, except food	0.003	0.996	0.000
L24.6 Irritant contact dermatitis due to food in contact with the skin	0.003	0.996	0.000
L24.5 Irritant contact dermatitis due to other chemical products	0.003	0.996	0.000
L24.4 Irritant contact dermatitis due to drugs in contact with the skin	0.003	0.996	0.000
L24.3 Irritant contact dermatitis due to cosmetics	0.003	0.996	0.000
L24.2 Irritant contact dermatitis due to solvents	0.003	0.996	0.000
L24.1 Irritant contact dermatitis due to oils and greases	0.003	0.996	0.000
L24.0 Irritant contact dermatitis due to detergents	0.003	0.996	0.000
F39 Unspecified mood [affective] disorder	0.004	0.996	0.000
N97.8 Female infertility of other origin	0.004	0.996	0.000
Z97 Presence of other devices	0.000	0.996	0.004
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.996	0.003
F30 Manic episode	0.003	0.996	0.000
G47.2 Disorders of the sleep-wake schedule	0.003	0.997	0.000
M84.8 Other disorders of continuity of bone	0.000	0.997	0.003
S22.11 Multiple fractures of thoracic spine (open)	0.000	0.997	0.003
M84.4 Pathological fracture, not elsewhere classified	0.000	0.997	0.003
N32.3 Diverticulum of bladder	0.003	0.997	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.003
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.997	0.003
F30.0 Hypomania	0.003	0.997	0.000
S22.41 Multiple fractures of ribs (open)	0.000	0.997	0.003
Z97.0 Presence of artificial eye	0.000	0.997	0.003
L21.8 Other seborrhoeic dermatitis	0.003	0.997	0.000
L21.1 Seborrhoeic infantile dermatitis	0.003	0.997	0.000
L21.0 Seborrhoea capitis	0.003	0.997	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.000	0.997	0.003
C88.0 Waldenstrom's macroglobulinaemia	0.000	0.997	0.003
M88.8 Paget's disease of other bones	0.003	0.997	0.000
Z97.4 Presence of external hearing-aid	0.000	0.997	0.003
S22.9 Fracture of bony thorax, part unspecified	0.000	0.997	0.003
S22.8 Fracture of other parts of bony thorax	0.000	0.997	0.003
W19.6 Industrial and construction area	0.000	0.997	0.003
F38 Other mood [affective] disorders	0.003	0.997	0.000
S22.31 Fracture of rib (open)	0.000	0.997	0.003
Z97.2 Presence of dental prosthetic device (complete)(partial)	0.000	0.997	0.003
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.997	0.003
D24 Benign neoplasm of breast	0.003	0.997	0.000
N97.0 Female infertility associated with anovulation	0.003	0.997	0.000
S22.21 Fracture of sternum (open)	0.000	0.997	0.003
L20.8 Other atopic dermatitis	0.002	0.997	0.001
L20.0 Besnier's prurigo	0.002	0.997	0.001
C18.6 Descending colon	0.003	0.997	0.000
M84.9 Disorder of continuity of bone, unspecified	0.000	0.997	0.003
Z97.8 Presence of other specified devices	0.000	0.997	0.003
M84.2 Delayed union of fracture	0.000	0.997	0.003
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.003	0.997	0.000
L23.8 Allergic contact dermatitis due to other agents	0.003	0.997	0.000
L23.7 Allergic contact dermatitis due to plants, except food	0.003	0.997	0.000
L23.6 Allergic contact dermatitis due to food in contact with the skin	0.003	0.997	0.000
L23.4 Allergic contact dermatitis due to dyes	0.003	0.997	0.000
L23.3 Allergic contact dermatitis due to drugs in contact with the skin	0.003	0.997	0.000
L23.2 Allergic contact dermatitis due to cosmetics	0.003	0.997	0.000
L23.0 Allergic contact dermatitis due to metals	0.003	0.997	0.000
M84.3 Stress fracture, not elsewhere classified	0.000	0.997	0.003
M88.0 Paget's disease of skull	0.003	0.997	0.000
N97.3 Female infertility of cervical origin	0.003	0.997	0.000
N97.2 Female infertility of uterine origin	0.003	0.997	0.000
W19.8 Other specified place	0.000	0.997	0.003
W19.5 Trade and service area	0.000	0.997	0.003
W19.0 Home	0.000	0.997	0.003
W19.7 Farm	0.000	0.997	0.003
T14.0 Superficial injury of unspecified body region	0.003	0.997	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.000	0.997	0.003
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.000	0.997	0.003
F30.9 Manic episode, unspecified	0.003	0.997	0.000
Z97.1 Presence of artificial limb (complete)(partial)	0.000	0.997	0.003
H50 Other strabismus	0.000	0.997	0.003
L23.1 Allergic contact dermatitis due to adhesives	0.003	0.997	0.000
Z99.0 Dependence on aspirator	0.003	0.997	0.000
N97.4 Female infertility associated with male factors	0.003	0.997	0.000
C09.9 Tonsil, unspecified	0.000	0.997	0.003
I83.0 Varicose veins of lower extremities with ulcer	0.003	0.997	0.000
F30.8 Other manic episodes	0.003	0.997	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.997	0.003
M84.01 Malunion of fracture (Shoulder region)	0.000	0.997	0.003
M84.89 Other disorders of continuity of bone (Site unspecified)	0.000	0.997	0.003
M84.88 Other disorders of continuity of bone (Other)	0.000	0.997	0.003
M84.86 Other disorders of continuity of bone (Lower leg)	0.000	0.997	0.003
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.000	0.997	0.003
M84.84 Other disorders of continuity of bone (Hand)	0.000	0.997	0.003
M84.83 Other disorders of continuity of bone (Forearm)	0.000	0.997	0.003
M84.82 Other disorders of continuity of bone (Upper arm)	0.000	0.997	0.003
M84.81 Other disorders of continuity of bone (Shoulder region)	0.000	0.997	0.003
M84.80 Other disorders of continuity of bone (Multiple sites)	0.000	0.997	0.003
M88.88 Paget's disease of other bones (Other)	0.003	0.997	0.000
L21.9 Seborrhoeic dermatitis, unspecified	0.002	0.997	0.000
J35.1 Hypertrophy of tonsils	0.000	0.997	0.003
T25 Burn and corrosion of ankle and foot	0.003	0.997	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.000	0.997	0.003
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.000	0.997	0.003
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.000	0.997	0.003
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.000	0.997	0.003
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.000	0.997	0.003
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.000	0.997	0.003
F30.1 Mania without psychotic symptoms	0.003	0.997	0.000
F30.2 Mania with psychotic symptoms	0.003	0.997	0.000
G47.4 Narcolepsy and cataplexy	0.003	0.997	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.000	0.997	0.003
Z03.9 Observation for suspected disease or condition, unspecified	0.003	0.997	0.000
Z97.3 Presence of spectacles and contact lenses	0.000	0.997	0.003
N32 Other disorders of bladder	0.003	0.997	0.000
Z99.9 Dependence on unspecified enabling machine and device	0.003	0.997	0.000
M88.85 Paget's disease of other bones (Pelvic region and thigh)	0.002	0.997	0.000
L23.9 Allergic contact dermatitis, unspecified cause	0.002	0.997	0.000
S22.5 Flail chest	0.000	0.997	0.002
F38.8 Other specified mood [affective] disorders	0.002	0.997	0.000
M88.89 Paget's disease of other bones (Site unspecified)	0.002	0.997	0.000
M88.87 Paget's disease of other bones (Ankle and foot)	0.002	0.997	0.000
M88.86 Paget's disease of other bones (Lower leg)	0.002	0.997	0.000
M88.84 Paget's disease of other bones (Hand)	0.002	0.997	0.000
M88.83 Paget's disease of other bones (Forearm)	0.002	0.997	0.000
M88.82 Paget's disease of other bones (Upper arm)	0.002	0.997	0.000
M88.81 Paget's disease of other bones (Shoulder region)	0.002	0.997	0.000
M88.80 Paget's disease of other bones (Multiple sites)	0.002	0.997	0.000
F38.0 Other single mood [affective] disorders	0.002	0.997	0.000
L20.9 Atopic dermatitis, unspecified	0.001	0.997	0.002
N97.9 Female infertility, unspecified	0.003	0.997	0.000
I83 Varicose veins of lower extremities	0.003	0.997	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.000	0.997	0.002
S22.80 Fracture of other parts of bony thorax (closed)	0.000	0.997	0.002
S22.91 Fracture of bony thorax, part unspecified (open)	0.000	0.997	0.002
S22.90 Fracture of bony thorax, part unspecified (closed)	0.000	0.997	0.002
M84.0 Malunion of fracture	0.000	0.997	0.003
D33.3 Cranial nerves	0.000	0.997	0.003
F38.1 Other recurrent mood [affective] disorders	0.002	0.997	0.000
F34 Persistent mood [affective] disorders	0.002	0.997	0.000
M24.0 Loose body in joint	0.000	0.997	0.003
S22.0 Fracture of thoracic vertebra	0.000	0.997	0.002
L29.0 Pruritus ani	0.002	0.997	0.000
W19.3 Sports and athletics area	0.000	0.997	0.002
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.002
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.000	0.997	0.002
L23.5 Allergic contact dermatitis due to other chemical products	0.002	0.997	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.998	0.002
W19.1 Residential institution	0.000	0.998	0.002
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.002	0.998	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.000	0.998	0.002
M84.98 Disorder of continuity of bone, unspecified (Other)	0.000	0.998	0.002
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.000	0.998	0.002
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.000	0.998	0.002
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.000	0.998	0.002
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.000	0.998	0.002
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.000	0.998	0.002
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.000	0.998	0.002
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.000	0.998	0.002
M84.29 Delayed union of fracture (Site unspecified)	0.000	0.998	0.002
M84.28 Delayed union of fracture (Other)	0.000	0.998	0.002
M84.27 Delayed union of fracture (Ankle and foot)	0.000	0.998	0.002
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.000	0.998	0.002
M84.24 Delayed union of fracture (Hand)	0.000	0.998	0.002
M84.23 Delayed union of fracture (Forearm)	0.000	0.998	0.002
M84.22 Delayed union of fracture (Upper arm)	0.000	0.998	0.002
M84.21 Delayed union of fracture (Shoulder region)	0.000	0.998	0.002
M84.20 Delayed union of fracture (Multiple sites)	0.000	0.998	0.002
Z31.2 In vitro fertilisation	0.000	0.998	0.002
Z99.4 Dependence on artificial heart	0.002	0.998	0.000
H50.6 Mechanical strabismus	0.000	0.998	0.002
J91 Pleural effusion in conditions classified elsewhere	0.002	0.998	0.000
M24.02 Loose body in joint (Upper arm)	0.000	0.998	0.002
M84.26 Delayed union of fracture (Lower leg)	0.000	0.998	0.002
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.000	0.998	0.002
M84.38 Stress fracture, not elsewhere classified (Other)	0.000	0.998	0.002
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.000	0.998	0.002
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.998	0.002
M84.34 Stress fracture, not elsewhere classified (Hand)	0.000	0.998	0.002
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.000	0.998	0.002
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.000	0.998	0.002
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.000	0.998	0.002
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.000	0.998	0.002
M88.09 Paget's disease of skull-Site unspec	0.002	0.998	0.000
M88.08 Paget's disease of skull-Other	0.002	0.998	0.000
M88.07 Paget's disease of skull-Ankle/Foot	0.002	0.998	0.000
M88.06 Paget's disease of skull-Lower Leg	0.002	0.998	0.000
M88.05 Paget's disease of skull-Pelvic/Thigh	0.002	0.998	0.000
M88.04 Paget's disease of skull-Hand	0.002	0.998	0.000
M88.03 Paget's disease of skull-Forearm	0.002	0.998	0.000
M88.02 Paget's disease of skull-Upper arm	0.002	0.998	0.000
M88.01 Paget's disease of skull-Shldr region	0.002	0.998	0.000
M88.00 Paget's disease of skull-Mult sites	0.002	0.998	0.000
D22.3 Melanocytic naevi of other and unspecified parts of face	0.000	0.998	0.002
D22 Melanocytic naevi	0.000	0.998	0.002
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
W19.09 Unspecified fall; Home; During unspecified activity	0.000	0.998	0.002
W19.08 Unspecified fall; Home; While engaged in other specified activities	0.000	0.998	0.002
W19.59 Unspecified fall; Trade and service area; During unspecified activity	0.000	0.998	0.002
W19.81 Unspecified fall; Other specified places; While engaged in leisure activity	0.000	0.998	0.002
L27 Dermatitis due to substances taken internally	0.002	0.998	0.001
D22.6 Melanocytic naevi of upper limb, including shoulder	0.000	0.998	0.002
H50.4 Other and unspecified heterotropia	0.000	0.998	0.002
H50.3 Intermittent heterotropia	0.000	0.998	0.002
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
J35 Chronic diseases of tonsils and adenoids	0.000	0.998	0.002
T25.3 Burn of third degree of ankle and foot	0.002	0.998	0.000
M10.96 Gout, unspecified (Lower leg)	0.000	0.998	0.002
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.000	0.998	0.002
Z46.3 Fitting and adjustment of dental prosthetic device	0.000	0.998	0.002
H50.8 Other specified strabismus	0.000	0.998	0.002
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.000	0.998	0.002
D22.5 Melanocytic naevi of trunk	0.000	0.998	0.002
N32.1 Vesicointestinal fistula	0.002	0.998	0.000
T25.7 Corrosion of third degree of ankle and foot	0.002	0.998	0.000
T25.6 Corrosion of second degree of ankle and foot	0.002	0.998	0.000
T25.5 Corrosion of first degree of ankle and foot	0.002	0.998	0.000
T25.4 Corrosion of unspecified degree of ankle and foot	0.002	0.998	0.000
T25.1 Burn of first degree of ankle and foot	0.002	0.998	0.000
A16.2 Tuberculosis of lung, without mention of bacteriological or histological confirmation	0.002	0.998	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
M84.04 Malunion of fracture (Hand)	0.000	0.998	0.002
N32.4 Rupture of bladder, nontraumatic	0.002	0.998	0.000
T25.0 Burn of unspecified degree of ankle and foot	0.002	0.998	0.000
G47.8 Other sleep disorders	0.002	0.998	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.998	0.002
N70.9 Salpingitis and oophoritis, unspecified	0.000	0.998	0.002
M80 Osteoporosis with pathological fracture	0.000	0.998	0.002
M84.06 Malunion of fracture (Lower leg)	0.000	0.998	0.002
S22.51 Flail chest (open)	0.000	0.998	0.002
H50.2 Vertical strabismus	0.000	0.998	0.002
M84.09 Malunion of fracture (Site unspecified)	0.000	0.998	0.002
M84.05 Malunion of fracture (Pelvic region and thigh)	0.000	0.998	0.002
M84.00 Malunion of fracture (Multiple sites)	0.000	0.998	0.002
N32.2 Vesical fistula, not elsewhere classified	0.002	0.998	0.000
Z99.2 Dependence on renal dialysis	0.002	0.998	0.000
M24.09 Loose body in joint (Site unspecified)	0.000	0.998	0.002
M24.08 Loose body in joint (Other)	0.000	0.998	0.002
M24.06 Loose body in joint-Lower leg	0.000	0.998	0.002
M24.05 Loose body in joint (Pelvic region and thigh)	0.000	0.998	0.002
M24.04 Loose body in joint (Hand)	0.000	0.998	0.002
M24.03 Loose body in joint (Forearm)	0.000	0.998	0.002
M24.00 Loose body in joint (Multiple sites)	0.000	0.998	0.002
S22.01 Fracture of thoracic vertebra (open)	0.000	0.998	0.002
C44.2 Skin of ear and external auricular canal	0.000	0.998	0.002
F34.9 Persistent mood [affective] disorder, unspecified	0.002	0.998	0.000
F34.8 Other persistent mood [affective] disorders	0.002	0.998	0.000
F34.0 Cyclothymia	0.002	0.998	0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically	0.002	0.998	0.000
B18.2 Chronic viral hepatitis C	0.002	0.998	0.000
G12.2 Motor neuron disease	0.002	0.998	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.998	0.002
G47.1 Disorders of excessive somnolence [hypersomnias]	0.002	0.998	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.002	0.998	0.000
H47.1 Papilloedema, unspecified	0.000	0.998	0.002
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
J35.2 Hypertrophy of adenoids	0.000	0.998	0.002
M54.46 Lumbago with sciatica (Lumbar region)	0.000	0.998	0.002
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.998	0.002
C49.2 Connective and soft tissue of lower limb, including hip	0.002	0.998	0.000
A16.9 Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation	0.002	0.998	0.000
D22.0 Melanocytic naevi of lip	0.000	0.998	0.002
H50.9 Strabismus, unspecified	0.000	0.998	0.002
A16.5 Tuberculous pleurisy, without mention of bacteriological or histological confirmation	0.002	0.998	0.000
D33.2 Brain, unspecified	0.000	0.998	0.002
L27.9 Dermatitis due to unspecified substance taken internally	0.001	0.998	0.001
L27.8 Dermatitis due to other substances taken internally	0.001	0.998	0.001
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.000	0.998	0.002
L29.9 Pruritus, unspecified	0.002	0.998	0.000
M75.3 Calcific tendinitis of shoulder	0.002	0.998	0.000
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.000	0.998	0.002
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.000	0.998	0.002
T31.0 Burns involving less than 10% of body surface	0.002	0.998	0.000
Z31 Procreative management	0.000	0.998	0.002
S02.20 Fracture of nasal bones (closed)	0.002	0.998	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.002	0.998	0.000
J35.0 Chronic tonsillitis	0.000	0.998	0.002
J93.8 Other pneumothorax	0.000	0.998	0.002
M80.8 Other osteoporosis with pathological fracture	0.000	0.998	0.002
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.000	0.998	0.002
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.998	0.002
L91.8 Other hypertrophic disorders of skin	0.000	0.998	0.002
Z31.8 Other procreative management	0.000	0.998	0.002
M84.08 Malunion of fracture (Other)	0.000	0.998	0.002
H21.5 Other adhesions and disruptions of iris and ciliary body	0.002	0.998	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.000	0.998	0.002
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.000	0.998	0.002
M80.2 Osteoporosis of disuse with pathological fracture	0.000	0.998	0.002
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.000	0.998	0.002
L27.2 Dermatitis due to ingested food	0.001	0.998	0.001
C92 Myeloid leukaemia	0.000	0.998	0.002
M41.99 Scoliosis, unspecified (Site unspecified)	0.002	0.998	0.000
Z35.8 Supervision of other high-risk pregnancies	0.002	0.998	0.000
A16.8 Other respiratory tuberculosis, without mention of bacteriological or histological confirmation	0.002	0.998	0.000
A16.7 Primary respiratory tuberculosis without mention of bacteriological or histological confirmation	0.002	0.998	0.000
A16.4 Tuberculosis of larynx, trachea and bronchus, without mention of bacteriological or histological confirmation	0.002	0.998	0.000
A16.3 Tuberculosis of intrathoracic lymph nodes, without mention of bacteriological or histological confirmation	0.002	0.998	0.000
A16.1 Tuberculosis of lung, bacteriological and histological examination not done	0.002	0.998	0.000
A16.0 Tuberculosis of lung, bacteriologically and histologically negative	0.002	0.998	0.000
C92.1 Chronic myeloid leukaemia	0.000	0.998	0.002
H40.1 Primary open-angle glaucoma	0.002	0.998	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.002	0.998	0.000
A15.2 Tuberculosis of lung, confirmed histologically	0.002	0.998	0.000
I74.5 Embolism and thrombosis of iliac artery	0.002	0.998	0.000
S19.9 Unspecified injury of neck	0.002	0.998	0.000
M24.01 Loose body in joint (Shoulder region)	0.000	0.998	0.002
L27.1 Localised skin eruption due to drugs and medicaments	0.001	0.998	0.001
D22.2 Melanocytic naevi of ear and external auricular canal	0.000	0.998	0.002
A18.1 Tuberculosis of genito-urinary system	0.002	0.998	0.000
D33 Benign neoplasm of brain and other parts of central nervous system	0.000	0.998	0.002
M84.02 Malunion of fracture (Upper arm)	0.000	0.998	0.001
V19.3 Pedal cyclist [any] injured in an unspecified nontraffic accident	0.000	0.998	0.002
Z46.8 Fitting and adjustment of other specified devices	0.000	0.998	0.002
H21 Other disorders of iris and ciliary body	0.002	0.998	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.002	0.998	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
A15 Respiratory tuberculosis, bacteriologically and histologically confirmed	0.002	0.998	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.002	0.998	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.000	0.998	0.002
M80.88 Other osteoporosis with pathological fracture (Other)	0.000	0.998	0.001
N32.0 Bladder-neck obstruction	0.002	0.998	0.000
Z31.9 Procreative management, unspecified	0.000	0.998	0.001
Z31.6 General counselling and advice on procreation	0.000	0.998	0.001
Z31.5 Genetic counselling	0.000	0.998	0.001
Z31.1 Artifical insemination	0.000	0.998	0.001
M19.90 Arthrosis, unspecified (Multiple sites)	0.002	0.998	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.998	0.002
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.001
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.001
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.001
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.001
M80.84 Other osteoporosis with pathological fracture (Hand)	0.000	0.998	0.001
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.001
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.001
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.001
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.001
S22.50 Flail chest (closed)	0.001	0.998	0.001
F34.1 Dysthymia	0.001	0.998	0.001
I60.9 Subarachnoid haemorrhage, unspecified	0.002	0.998	0.000
S13.4 Sprain and strain of cervical spine	0.000	0.998	0.002
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.000	0.998	0.001
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.000	0.998	0.001
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.000	0.998	0.001
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.000	0.998	0.001
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations