TreeWAS – Variant ID: rs34411452

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
L40.9 Psoriasis, unspecified	0.000	0.912	0.088
L40 Psoriasis	0.000	0.917	0.083
L40.0 Psoriasis vulgaris	0.000	0.924	0.076
L40-L45 Papulosquamous disorders	0.000	0.931	0.069
L43 Lichen planus	0.000	0.935	0.065
L43.9 Lichen planus, unspecified	0.000	0.937	0.063
L40.8 Other psoriasis	0.000	0.939	0.061
L40.4 Guttate psoriasis	0.000	0.940	0.059
L40.3 Pustulosis palmaris et plantaris	0.000	0.940	0.059
L40.2 Acrodermatitis continua	0.000	0.940	0.059
L40.1 Generalised pustular psoriasis	0.000	0.940	0.059
L40.5 Arthropathic psoriasis	0.000	0.944	0.056
L42 Pityriasis rosea	0.000	0.944	0.056
L44 Other papulosquamous disorders	0.000	0.950	0.049
L41 Parapsoriasis	0.000	0.950	0.049
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.950	0.049
L43.8 Other lichen planus	0.000	0.952	0.047
L43.3 Subacute (active) lichen planus	0.000	0.953	0.047
L43.2 Lichenoid drug reaction	0.000	0.953	0.047
L43.1 Bullous lichen planus	0.000	0.953	0.047
L43.0 Hypertrophic lichen planus	0.000	0.953	0.047
D22.3 Melanocytic naevi of other and unspecified parts of face	0.039	0.961	0.000
L41.9 Parapsoriasis, unspecified	0.000	0.964	0.036
L41.8 Other parapsoriasis	0.000	0.964	0.036
L41.5 Retiform parapsoriasis	0.000	0.964	0.036
L41.4 Large plaque parapsoriasis	0.000	0.964	0.036
L41.3 Small plaque parapsoriasis	0.000	0.964	0.036
L41.2 Lymphomatoid papulosis	0.000	0.964	0.036
L41.1 Pityriasis lichenoides chronica	0.000	0.964	0.036
L41.0 Pityriasis lichenoides et varioliformis acuta	0.000	0.964	0.036
L44.9 Papulosquamous disorder, unspecified	0.000	0.964	0.036
L44.8 Other specified papulosquamous disorders	0.000	0.964	0.036
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.000	0.964	0.036
L44.3 Lichen ruber moniliformis	0.000	0.964	0.036
L44.2 Lichen striatus	0.000	0.964	0.036
L44.1 Lichen nitidus	0.000	0.964	0.036
L44.0 Pityriasis rubra pilaris	0.000	0.964	0.036
C34.9 Bronchus or lung, unspecified	0.000	0.973	0.027
C34 Malignant neoplasm of bronchus and lung	0.000	0.975	0.025
C34.1 Upper lobe, bronchus or lung	0.000	0.978	0.022
C34.3 Lower lobe, bronchus or lung	0.000	0.978	0.022
C34.0 Main bronchus	0.000	0.979	0.021
C34.2 Middle lobe, bronchus or lung	0.000	0.981	0.019
C34.8 Overlapping lesion of bronchus and lung	0.000	0.984	0.016
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.000	0.987	0.013
D22.4 Melanocytic naevi of scalp and neck	0.013	0.987	0.000
D22 Melanocytic naevi	0.013	0.987	0.000
C32 Malignant neoplasm of larynx	0.000	0.988	0.012
D22.5 Melanocytic naevi of trunk	0.011	0.989	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.000	0.990	0.010
C32.1 Supraglottis	0.000	0.990	0.010
C32.9 Larynx, unspecified	0.000	0.990	0.010
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.000	0.990	0.010
C31 Malignant neoplasm of accessory sinuses	0.000	0.990	0.010
C33 Malignant neoplasm of trachea	0.000	0.990	0.010
C38 Malignant neoplasm of heart, mediastinum and pleura	0.000	0.990	0.010
N80.9 Endometriosis, unspecified	0.009	0.991	0.000
I67.1 Cerebral aneurysm, nonruptured	0.000	0.991	0.009
D22.6 Melanocytic naevi of upper limb, including shoulder	0.009	0.991	0.000
C32.8 Overlapping lesion of larynx	0.000	0.991	0.009
C32.3 Laryngeal cartilage	0.000	0.991	0.009
C32.2 Subglottis	0.000	0.991	0.009
D22.2 Melanocytic naevi of ear and external auricular canal	0.008	0.991	0.000
D22.9 Melanocytic naevi, unspecified	0.008	0.992	0.000
C30.0 Nasal cavity	0.000	0.992	0.008
C32.0 Glottis	0.000	0.992	0.008
C37 Malignant neoplasm of thymus	0.000	0.992	0.008
C30.1 Middle ear	0.000	0.992	0.008
I67 Other cerebrovascular diseases	0.000	0.992	0.008
I67.2 Cerebral atherosclerosis	0.000	0.992	0.008
D22.1 Melanocytic naevi of eyelid, including canthus	0.008	0.992	0.000
D22.0 Melanocytic naevi of lip	0.007	0.992	0.000
C31.9 Accessory sinus, unspecified	0.000	0.993	0.007
C31.8 Overlapping lesion of accessory sinuses	0.000	0.993	0.007
C31.3 Sphenoidal sinus	0.000	0.993	0.007
C31.2 Frontal sinus	0.000	0.993	0.007
C31.1 Ethmoidal sinus	0.000	0.993	0.007
C31.0 Maxillary sinus	0.000	0.993	0.007
C39.9 Ill-defined sites within the respiratory system	0.000	0.993	0.007
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.000	0.993	0.007
C39.0 Upper respiratory tract, part unspecified	0.000	0.993	0.007
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.000	0.993	0.007
C38.3 Mediastinum, part unspecified	0.000	0.993	0.007
C38.2 Posterior mediastinum	0.000	0.993	0.007
C38.1 Anterior mediastinum	0.000	0.993	0.007
C38.0 Heart	0.000	0.993	0.007
G93.3 Postviral fatigue syndrome	0.000	0.993	0.007
C38.4 Pleura	0.000	0.993	0.007
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.993	0.007
I67.8 Other specified cerebrovascular diseases	0.000	0.993	0.006
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.994	0.006
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.994	0.006
I67.5 Moyamoya disease	0.000	0.994	0.006
I67.4 Hypertensive encephalopathy	0.000	0.994	0.006
I67.3 Progressive vascular leukoencephalopathy	0.000	0.994	0.006
N42.9 Disorder of prostate, unspecified	0.000	0.994	0.006
Z99.2 Dependence on renal dialysis	0.006	0.994	0.000
Z99.1 Dependence on respirator	0.006	0.994	0.000
D86.9 Sarcoidosis, unspecified	0.005	0.995	0.000
S91.1 Open wound of toe(s) without damage to nail	0.005	0.995	0.000
K51.2 Ulcerative (chronic) proctitis	0.000	0.995	0.005
N76.8 Other specified inflammation of vagina and vulva	0.000	0.996	0.004
R20.2 Paraesthesia of skin	0.000	0.996	0.004
D22.7 Melanocytic naevi of lower limb, including hip	0.004	0.996	0.000
G45.4 Transient global amnesia	0.004	0.996	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.004	0.996	0.000
N76.2 Acute vulvitis	0.000	0.996	0.004
M35.3 Polymyalgia rheumatica	0.000	0.996	0.004
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.996	0.004
N76 Other inflammation of vagina and vulva	0.000	0.996	0.004
N76.0 Acute vaginitis	0.000	0.996	0.004
S91.0 Open wound of ankle	0.004	0.996	0.000
S91 Open wound of ankle and foot	0.004	0.996	0.000
D86 Sarcoidosis	0.004	0.996	0.000
C50.8 Overlapping lesion of breast	0.004	0.996	0.000
N60.3 Fibrosclerosis of breast	0.003	0.997	0.000
N76.6 Ulceration of vulva	0.000	0.997	0.003
D41.4 Bladder	0.003	0.997	0.000
N88.2 Stricture and stenosis of cervix uteri	0.000	0.997	0.003
I67.9 Cerebrovascular disease, unspecified	0.000	0.997	0.003
N76.1 Subacute and chronic vaginitis	0.000	0.997	0.003
N76.4 Abscess of vulva	0.000	0.997	0.003
Z99.8 Dependence on other enabling machines and devices	0.003	0.997	0.000
N30.1 Interstitial cystitis (chronic)	0.003	0.997	0.000
Z99.9 Dependence on unspecified enabling machine and device	0.003	0.997	0.000
Z99.4 Dependence on artificial heart	0.003	0.997	0.000
Z99.0 Dependence on aspirator	0.003	0.997	0.000
D86.0 Sarcoidosis of lung	0.003	0.997	0.000
D86.1 Sarcoidosis of lymph nodes	0.003	0.997	0.000
M79.67 Pain in limb (Ankle and foot)	0.003	0.997	0.000
J35.1 Hypertrophy of tonsils	0.003	0.997	0.000
C18.9 Colon, unspecified	0.000	0.997	0.003
N60.1 Diffuse cystic mastopathy	0.003	0.997	0.000
S91.7 Multiple open wounds of ankle and foot	0.003	0.997	0.000
S91.2 Open wound of toe(s) with damage to nail	0.003	0.997	0.000
D86.3 Sarcoidosis of skin	0.003	0.997	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.003	0.997	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.003	0.997	0.000
D86.8 Sarcoidosis of other and combined sites	0.003	0.997	0.000
C09.9 Tonsil, unspecified	0.000	0.997	0.003
I63.8 Other cerebral infarction	0.000	0.997	0.003
K83.8 Other specified diseases of biliary tract	0.003	0.997	0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons	0.000	0.997	0.003
M10.97 Gout, unspecified (Ankle and foot)	0.003	0.997	0.000
H92.0 Otalgia	0.000	0.997	0.003
N76.3 Subacute and chronic vulvitis	0.000	0.997	0.002
I60-I69 Cerebrovascular diseases	0.000	0.998	0.002
N76.5 Ulceration of vagina	0.000	0.998	0.002
C01 Malignant neoplasm of base of tongue	0.000	0.998	0.002
C10.9 Oropharynx, unspecified	0.000	0.998	0.002
N60.4 Mammary duct ectasia	0.002	0.998	0.000
C09 Malignant neoplasm of tonsil	0.000	0.998	0.002
I69 Sequelae of cerebrovascular disease	0.000	0.998	0.002
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.998	0.002
N42 Other disorders of prostate	0.000	0.998	0.002
I61 Intracerebral haemorrhage	0.000	0.998	0.002
E10.9 Without complications	0.002	0.998	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.998	0.002
C10 Malignant neoplasm of oropharynx	0.000	0.998	0.002
I65.2 Occlusion and stenosis of carotid artery	0.000	0.998	0.002
S91.3 Open wound of other parts of foot	0.002	0.998	0.000
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
S82.10 Fracture of upper end of tibia (closed)	0.002	0.998	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.998	0.002
S92.00 Fracture of calcaneus (closed)	0.000	0.998	0.002
S90.3 Contusion of other and unspecified parts of foot	0.002	0.998	0.000
N42.0 Calculus of prostate	0.000	0.998	0.002
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.000	0.998	0.002
D41.0 Kidney	0.002	0.998	0.000
D25.0 Submucous leiomyoma of uterus	0.000	0.998	0.002
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.002	0.998	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.998	0.002
N42.8 Other specified disorders of prostate	0.000	0.998	0.002
I63 Cerebral infarction	0.000	0.998	0.002
C71.9 Brain, unspecified	0.000	0.998	0.002
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.998	0.002
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.998	0.002
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.998	0.002
S90.8 Other superficial injuries of ankle and foot	0.002	0.998	0.000
C07 Malignant neoplasm of parotid gland	0.000	0.998	0.002
S90-S99 Injuries to the ankle and foot	0.002	0.998	0.000
I62 Other nontraumatic intracranial haemorrhage	0.000	0.998	0.002
C09.8 Overlapping lesion of tonsil	0.000	0.998	0.002
C09.1 Tonsillar pillar (anterior) (posterior)	0.000	0.998	0.002
C09.0 Tonsillar fossa	0.000	0.998	0.002
C62.9 Testis, unspecified	0.000	0.998	0.002
I61.8 Other intracerebral haemorrhage	0.000	0.998	0.002
S30.1 Contusion of abdominal wall	0.000	0.998	0.002
S90.9 Superficial injury of ankle and foot, unspecified	0.002	0.998	0.000
H83.0 Labyrinthitis	0.000	0.998	0.002
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.998	0.002
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.998	0.002
I69.0 Sequelae of subarachnoid haemorrhage	0.001	0.998	0.001
N42.3 Dysplasia of prostate	0.000	0.998	0.002
X62.9 Unspecified place	0.000	0.998	0.002
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.998	0.002
S90.1 Contusion of toe(s) without damage to nail	0.002	0.998	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.998	0.002
N30.2 Other chronic cystitis	0.002	0.998	0.000
C05 Malignant neoplasm of palate	0.000	0.998	0.002
C12 Malignant neoplasm of pyriform sinus	0.000	0.998	0.002
C04 Malignant neoplasm of floor of mouth	0.000	0.998	0.002
R20 Disturbances of skin sensation	0.000	0.998	0.002
C10.8 Overlapping lesion of oropharynx	0.000	0.998	0.002
C10.4 Branchial cleft	0.000	0.998	0.002
C10.3 Posterior wall of oropharynx	0.000	0.998	0.002
C10.2 Lateral wall of oropharynx	0.000	0.998	0.002
C10.1 Anterior surface of epiglottis	0.000	0.998	0.002
C10.0 Vallecula	0.000	0.998	0.002
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.998	0.002
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.000	0.998	0.002
S96 Injury of muscle and tendon at ankle and foot level	0.002	0.998	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.002	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.002	0.998	0.000
X63.0 Home	0.000	0.998	0.002
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.998	0.002
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.998	0.002
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.998	0.002
M20.2 Hallux rigidus	0.002	0.998	0.000
N60 Benign mammary dysplasia	0.002	0.998	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.000	0.998	0.002
T83.0 Mechanical complication of urinary (indwelling) catheter	0.000	0.998	0.002
S97 Crushing injury of ankle and foot	0.002	0.998	0.000
F10.1 Harmful use	0.000	0.998	0.002
J02.9 Acute pharyngitis, unspecified	0.002	0.998	0.000
C13 Malignant neoplasm of hypopharynx	0.000	0.998	0.002
C03 Malignant neoplasm of gum	0.000	0.998	0.002
C00 Malignant neoplasm of lip	0.000	0.998	0.002
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.998	0.002
X78.0 Home	0.000	0.998	0.002
D41.9 Urinary organ, unspecified	0.002	0.998	0.000
D41.7 Other urinary organs	0.002	0.998	0.000
D41.3 Urethra	0.002	0.998	0.000
D41.1 Renal pelvis	0.002	0.998	0.000
C05.1 Soft palate	0.000	0.998	0.002
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.998	0.002
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.998	0.002
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.998	0.001
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.998	0.001
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.001
I68.0 Cerebral amyloid angiopathy	0.000	0.998	0.001
N18.5 Chronic kidney disease, stage 5	0.002	0.998	0.000
M67.1 Other contracture of tendon (sheath)	0.000	0.998	0.002
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.002	0.998	0.000
Z89.9 Acquired absence of limb, unspecified	0.002	0.998	0.000
N18.0 End-stage renal disease	0.002	0.998	0.000
C11 Malignant neoplasm of nasopharynx	0.000	0.998	0.002
S98 Traumatic amputation of ankle and foot	0.002	0.998	0.000
S95 Injury of blood vessels at ankle and foot level	0.002	0.998	0.000
S94 Injury of nerves at ankle and foot level	0.002	0.998	0.000
C04.9 Floor of mouth, unspecified	0.000	0.998	0.002
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.998	0.001
K50.9 Crohn's disease, unspecified	0.002	0.998	0.000
S92.0 Fracture of calcaneus	0.001	0.998	0.001
C08 Malignant neoplasm of other and unspecified major salivary glands	0.000	0.998	0.001
C14.0 Pharynx, unspecified	0.000	0.998	0.001
I65.1 Occlusion and stenosis of basilar artery	0.000	0.998	0.001
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.998	0.001
R20.0 Anaesthesia of skin	0.000	0.998	0.002
S97.8 Crushing injury of other parts of ankle and foot	0.001	0.998	0.000
D41.2 Ureter	0.001	0.998	0.000
G61.0 Guillain-Barre syndrome	0.000	0.998	0.002
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.998	0.001
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.998	0.001
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.998	0.001
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.998	0.001
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.998	0.001
O04.9 Complete or unspecified, without complication	0.002	0.998	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.001	0.998	0.000
C05.8 Overlapping lesion of palate	0.000	0.998	0.001
C05.2 Uvula	0.000	0.998	0.001
C05.0 Hard palate	0.000	0.998	0.001
C04.8 Overlapping lesion of floor of mouth	0.000	0.998	0.001
C04.1 Lateral floor of mouth	0.000	0.998	0.001
C04.0 Anterior floor of mouth	0.000	0.998	0.001
C71.1 Frontal lobe	0.000	0.998	0.002
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.998	0.001
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.998	0.001
K05.3 Chronic periodontitis	0.002	0.998	0.000
M34.9 Systemic sclerosis, unspecified	0.002	0.998	0.000
R20.3 Hyperaesthesia	0.000	0.998	0.001
S90.0 Contusion of ankle	0.001	0.998	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.001	0.998	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.001	0.998	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.001	0.998	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.001	0.998	0.000
Z89.5 Acquired absence of leg at or below knee	0.002	0.998	0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.000	0.998	0.002
C14.8 Overlapping lesion of lip, oral cavity and pharynx	0.000	0.998	0.001
C14.2 Waldeyer's ring	0.000	0.998	0.001
I63.9 Cerebral infarction, unspecified	0.000	0.998	0.002
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
S92 Fracture of foot, except ankle	0.001	0.998	0.000
C05.9 Palate, unspecified	0.000	0.998	0.001
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.998	0.001
R20.1 Hypoaesthesia of skin	0.000	0.998	0.001
R73.9 Hyperglycaemia, unspecified	0.000	0.998	0.002
C00.9 Lip, unspecified	0.000	0.998	0.001
C00.8 Overlapping lesion of lip	0.000	0.998	0.001
C00.6 Commissure of lip	0.000	0.998	0.001
C00.5 Lip, unspecified, inner aspect	0.000	0.998	0.001
C00.4 Lower lip, inner aspect	0.000	0.998	0.001
C00.3 Upper lip, inner aspect	0.000	0.998	0.001
C00.2 External lip, unspecified	0.000	0.998	0.001
C00.1 External lower lip	0.000	0.998	0.001
C00.0 External upper lip	0.000	0.998	0.001
C03.9 Gum, unspecified	0.000	0.998	0.001
C03.1 Lower gum	0.000	0.998	0.001
C03.0 Upper gum	0.000	0.998	0.001
C13.9 Hypopharynx, unspecified	0.000	0.998	0.001
C13.8 Overlapping lesion of hypopharynx	0.000	0.998	0.001
C13.2 Posterior wall of hypopharynx	0.000	0.998	0.001
C13.1 Aryepiglottic fold, hypopharyngeal aspect	0.000	0.998	0.001
C13.0 Postcricoid region	0.000	0.998	0.001
G11.9 Hereditary ataxia, unspecified	0.001	0.998	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.998	0.001
N42.2 Atrophy of prostate	0.000	0.998	0.001
S97.1 Crushing injury of toe(s)	0.001	0.998	0.000
S97.0 Crushing injury of ankle	0.001	0.998	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.000	0.998	0.002
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.001	0.998	0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.000	0.998	0.001
Z89 Acquired absence of limb	0.002	0.998	0.000
I62.1 Nontraumatic extradural haemorrhage	0.000	0.998	0.001
N60.9 Benign mammary dysplasia, unspecified	0.001	0.998	0.000
S92.3 Fracture of metatarsal bone	0.001	0.998	0.000
Z96.7 Presence of other bone and tendon implants	0.000	0.998	0.002
X78 Intentional self-harm by sharp object	0.000	0.998	0.001
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.998	0.001
S92.30 Fracture of metatarsal bone (closed)	0.001	0.998	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.998	0.001
N42.1 Congestion and haemorrhage of prostate	0.000	0.998	0.001
Z89.2 Acquired absence of upper limb above wrist	0.001	0.998	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.000	0.998	0.001
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.998	0.001
Z89.6 Acquired absence of leg above knee	0.001	0.998	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.000	0.998	0.001
C02.9 Tongue, unspecified	0.000	0.999	0.001
C11.8 Overlapping lesion of nasopharynx	0.000	0.999	0.001
C11.3 Anterior wall of nasopharynx	0.000	0.999	0.001
C11.2 Lateral wall of nasopharynx	0.000	0.999	0.001
C11.1 Posterior wall of nasopharynx	0.000	0.999	0.001
C11.0 Superior wall of nasopharynx	0.000	0.999	0.001
I69.3 Sequelae of cerebral infarction	0.000	0.999	0.001
S94.9 Injury of unspecified nerve at ankle and foot level	0.001	0.999	0.000
S94.8 Injury of other nerves at ankle and foot level	0.001	0.999	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.001	0.999	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.001	0.999	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.001	0.999	0.000
S94.1 Injury of medial plantar nerve	0.001	0.999	0.000
S94.0 Injury of lateral plantar nerve	0.001	0.999	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.001	0.999	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.001	0.999	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.001	0.999	0.000
S95.2 Injury of dorsal vein of foot	0.001	0.999	0.000
S95.1 Injury of plantar artery of foot	0.001	0.999	0.000
S95.0 Injury of dorsal artery of foot	0.001	0.999	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.001	0.999	0.000
S98.3 Traumatic amputation of other parts of foot	0.001	0.999	0.000
S98.2 Traumatic amputation of two or more toes	0.001	0.999	0.000
S98.1 Traumatic amputation of one toe	0.001	0.999	0.000
S98.0 Traumatic amputation of foot at ankle level	0.001	0.999	0.000
E10 Insulin-dependent diabetes mellitus	0.001	0.999	0.000
S99 Other and unspecified injuries of ankle and foot	0.001	0.999	0.000
S92.01 Fracture of calcaneus (open)	0.001	0.999	0.001
C81.9 Hodgkin's disease, unspecified	0.001	0.999	0.000
E10.7 With multiple complications	0.001	0.999	0.000
F81.9 Developmental disorder of scholastic skills, unspecified	0.000	0.999	0.001
D80-D89 Certain disorders involving the immune mechanism	0.001	0.999	0.000
C08.8 Overlapping lesion of major salivary glands	0.000	0.999	0.001
C08.1 Sublingual gland	0.000	0.999	0.001
C08.0 Submandibular gland	0.000	0.999	0.001
C71 Malignant neoplasm of brain	0.000	0.999	0.001
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.999	0.001
E10.6 With other specified complications	0.001	0.999	0.000
E10.2 With renal complications	0.001	0.999	0.000
S92.4 Fracture of great toe	0.001	0.999	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.000	0.999	0.001
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.999	0.001
X62.0 Home	0.000	0.999	0.001
X62.8 Other specified place	0.000	0.999	0.001
X62.7 Farm	0.000	0.999	0.001
X62.6 Industrial and construction area	0.000	0.999	0.001
X62.5 Trade and service area	0.000	0.999	0.001
X62.4 Street and highway	0.000	0.999	0.001
X62.3 Sports and athletics area	0.000	0.999	0.001
X62.2 School, other institution and public administrative area	0.000	0.999	0.001
X62.1 Residential institution	0.000	0.999	0.001
D82 Immunodeficiency associated with other major defects	0.001	0.999	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.001	0.999	0.000
G94.2 Hydrocephalus in other diseases classified elsewhere	0.001	0.999	0.000
S92.9 Fracture of foot, unspecified	0.001	0.999	0.000
S92.5 Fracture of other toe	0.001	0.999	0.000
S92.2 Fracture of other tarsal bone(s)	0.001	0.999	0.000
C11.9 Nasopharynx, unspecified	0.000	0.999	0.001
C71.3 Parietal lobe	0.000	0.999	0.001
J94.2 Haemothorax	0.000	0.999	0.001
K62.9 Disease of anus and rectum, unspecified	0.000	0.999	0.001
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.999	0.001
X63.9 Unspecified place	0.000	0.999	0.001
X63.8 Other specified place	0.000	0.999	0.001
X63.7 Farm	0.000	0.999	0.001
X63.6 Industrial and construction area	0.000	0.999	0.001
X63.5 Trade and service area	0.000	0.999	0.001
X63.4 Street and highway	0.000	0.999	0.001
X63.3 Sports and athletics area	0.000	0.999	0.001
X63.2 School, other institution and public administrative area	0.000	0.999	0.001
X63.1 Residential institution	0.000	0.999	0.001
Y85.9 Sequelae of other and unspecified transport accidents	0.001	0.999	0.000
Z89.8 Acquired absence of upper and lower limbs [any level]	0.001	0.999	0.000
Z89.3 Acquired absence of both upper limbs [any level]	0.001	0.999	0.000
Z89.1 Acquired absence of hand and wrist	0.001	0.999	0.000
S92.31 Fracture of metatarsal bone (open)	0.001	0.999	0.000
A39.0 Meningococcal meningitis	0.001	0.999	0.000
D82.1 Di George's syndrome	0.001	0.999	0.000
S99.8 Other specified injuries of ankle and foot	0.001	0.999	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.000	0.999	0.001
X78.9 Unspecified place	0.000	0.999	0.001
X78.8 Other specified place	0.000	0.999	0.001
X78.7 Farm	0.000	0.999	0.001
X78.6 Industrial and construction area	0.000	0.999	0.001
X78.5 Trade and service area	0.000	0.999	0.001
X78.4 Street and highway	0.000	0.999	0.001
X78.3 Sports and athletics area	0.000	0.999	0.001
X78.2 School, other institution and public administrative area	0.000	0.999	0.001
X78.1 Residential institution	0.000	0.999	0.001
C02.8 Overlapping lesion of tongue	0.000	0.999	0.001
C02.3 Anterior two-thirds of tongue, part unspecified	0.000	0.999	0.001
C02.0 Dorsal surface of tongue	0.000	0.999	0.001
C06.8 Overlapping lesion of other and unspecified parts of mouth	0.000	0.999	0.001
C06.1 Vestibule of mouth	0.000	0.999	0.001
C06.0 Cheek mucosa	0.000	0.999	0.001
E10.4 With neurological complications	0.001	0.999	0.000
Z89.4 Acquired absence of foot and ankle	0.001	0.999	0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.001	0.999	0.000
C08.9 Major salivary gland, unspecified	0.000	0.999	0.001
F22.0 Delusional disorder	0.000	0.999	0.001
L50.9 Urticaria, unspecified	0.000	0.999	0.001
O00.9 Ectopic pregnancy, unspecified	0.001	0.999	0.000
R20.8 Other and unspecified disturbances of skin sensation	0.000	0.999	0.001
S99.7 Multiple injuries of ankle and foot	0.001	0.999	0.000
D84 Other immunodeficiencies	0.001	0.999	0.000
S92.50 Fracture of other toe (closed)	0.001	0.999	0.000
C71.7 Brain stem	0.000	0.999	0.001
C71.6 Cerebellum	0.000	0.999	0.001
C71.5 Cerebral ventricle	0.000	0.999	0.001
D84.1 Defects in the complement system	0.001	0.999	0.000
N75.1 Abscess of Bartholin's gland	0.000	0.999	0.001
S92.1 Fracture of talus	0.001	0.999	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.000	0.999	0.001
D83 Common variable immunodeficiency	0.001	0.999	0.000
D81 Combined immunodeficiencies	0.001	0.999	0.000
M10.92 Gout, unspecified (Upper arm)	0.001	0.999	0.000
M24.07 Loose body in joint (Ankle and foot)	0.001	0.999	0.000
C71.0 Cerebrum, except lobes and ventricles	0.000	0.999	0.001
R06.2 Wheezing	0.001	0.999	0.000
X60-X84 Intentional self-harm	0.000	0.999	0.001
S92.41 Fracture of great toe (open)	0.001	0.999	0.000
S92.40 Fracture of great toe (closed)	0.001	0.999	0.000
X62.09 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified: Home: During unspecified activity	0.000	0.999	0.001
D82.9 Immunodeficiency associated with major defect, unspecified	0.001	0.999	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.001	0.999	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.001	0.999	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.001	0.999	0.000
D82.2 Immunodeficiency with short-limbed stature	0.001	0.999	0.000
D82.0 Wiskott-Aldrich syndrome	0.001	0.999	0.000
G11.4 Hereditary spastic paraplegia	0.001	0.999	0.000
K05.5 Other periodontal diseases	0.001	0.999	0.000
K05.1 Chronic gingivitis	0.001	0.999	0.000
S92.7 Multiple fractures of foot	0.001	0.999	0.000
S93.4 Sprain and strain of ankle	0.001	0.999	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.001	0.999	0.000
S93.5 Sprain and strain of toe(s)	0.001	0.999	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.001	0.999	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.001	0.999	0.000
X68 Intentional self-poisoning by and exposure to pesticides	0.000	0.999	0.001
S92.21 Fracture of other tarsal bone(s) (open)	0.001	0.999	0.000
S92.91 Fracture of foot, unspecified (open)	0.001	0.999	0.000
S92.90 Fracture of foot, unspecified (closed)	0.001	0.999	0.000
C71.8 Overlapping lesion of brain	0.000	0.999	0.001
E10.3 With ophthalmic complications	0.001	0.999	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.001	0.999	0.000
L50.0 Allergic urticaria	0.000	0.999	0.001
X68.9 Unspecified place	0.000	0.999	0.001
X63.99 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system; Unspecified place ;During unspecified activity	0.000	0.999	0.001
X78.99 Intentional self-harm by sharp object: Unspecified place: During unspecified activity	0.000	0.999	0.001
C06.2 Retromolar area	0.000	0.999	0.001
C71.4 Occipital lobe	0.000	0.999	0.001
L50.1 Idiopathic urticaria	0.000	0.999	0.001
S92.20 Fracture of other tarsal bone(s) (closed)	0.001	0.999	0.000
C81.0 Lymphocytic predominance	0.001	0.999	0.000
E10.1 With ketoacidosis	0.001	0.999	0.000
O20.0 Threatened abortion	0.001	0.999	0.000
S93.0 Dislocation of ankle joint	0.001	0.999	0.000
M10.90 Gout, unspecified (Multiple sites)	0.001	0.999	0.000
S92.11 Fracture of talus (open)	0.001	0.999	0.000
C02.4 Lingual tonsil	0.000	0.999	0.001
C06.9 Mouth, unspecified	0.000	0.999	0.001
C18.4 Transverse colon	0.000	0.999	0.001
D81.9 Combined immunodeficiency, unspecified	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations