TreeWAS – Variant ID: rs349114

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C79 Secondary malignant neoplasm of other sites	0.364	0.636	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.354	0.646	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.350	0.650	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.341	0.659	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.327	0.673	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.322	0.678	0.000
C80 Malignant neoplasm without specification of site	0.312	0.688	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.311	0.689	0.000
C78.7 Secondary malignant neoplasm of liver	0.308	0.692	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.301	0.699	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.291	0.709	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.289	0.711	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.273	0.727	0.000
C79.2 Secondary malignant neoplasm of skin	0.272	0.728	0.000
C80.9 Malignant neoplasm, unspecified	0.271	0.729	0.000
C79.6 Secondary malignant neoplasm of ovary	0.268	0.732	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.258	0.742	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.239	0.761	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.229	0.771	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.214	0.785	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.203	0.797	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.166	0.834	0.000
C76.0 Head, face and neck	0.159	0.841	0.000
C76.8 Overlapping lesion of other and ill-defined sites	0.145	0.854	0.000
C76.7 Other ill-defined sites	0.145	0.854	0.000
C76.5 Lower limb	0.145	0.854	0.000
C76.4 Upper limb	0.145	0.854	0.000
C76.2 Abdomen	0.145	0.854	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.139	0.861	0.000
C78.2 Secondary malignant neoplasm of pleura	0.139	0.861	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.136	0.864	0.000
C76.1 Thorax	0.128	0.871	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.127	0.873	0.000
C77.1 Intrathoracic lymph nodes	0.123	0.877	0.000
C76.3 Pelvis	0.113	0.886	0.000
C77.9 Lymph node, unspecified	0.112	0.888	0.000
C77.0 Lymph nodes of head, face and neck	0.110	0.890	0.000
C77.8 Lymph nodes of multiple regions	0.083	0.917	0.000
C77.4 Inguinal and lower limb lymph nodes	0.073	0.927	0.000
C77.5 Intrapelvic lymph nodes	0.072	0.928	0.000
C78.0 Secondary malignant neoplasm of lung	0.063	0.937	0.000
C77.2 Intra-abdominal lymph nodes	0.058	0.942	0.000
B07 Viral warts	0.000	0.980	0.020
A04.7 Enterocolitis due to Clostridium difficile	0.000	0.982	0.018
K37 Unspecified appendicitis	0.015	0.985	0.000
L05.0 Pilonidal cyst with abscess	0.000	0.986	0.014
I42.0 Dilated cardiomyopathy	0.011	0.989	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.991	0.009
E27 Other disorders of adrenal gland	0.000	0.992	0.008
E27.1 Primary adrenocortical insufficiency	0.000	0.992	0.008
E27.8 Other specified disorders of adrenal gland	0.000	0.992	0.008
E27.9 Disorder of adrenal gland, unspecified	0.000	0.993	0.007
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.000	0.993	0.007
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.993	0.007
E27.5 Adrenomedullary hyperfunction	0.000	0.994	0.006
E27.0 Other adrenocortical overactivity	0.000	0.994	0.006
B00 Herpesviral [herpes simplex] infections	0.000	0.994	0.006
C77.3 Axillary and upper limb lymph nodes	0.006	0.994	0.000
D73.0 Hyposplenism	0.005	0.995	0.000
B00.1 Herpesviral vesicular dermatitis	0.000	0.995	0.005
A04 Other bacterial intestinal infections	0.000	0.995	0.005
E27.2 Addisonian crisis	0.000	0.995	0.005
B00.5 Herpesviral ocular disease	0.000	0.995	0.005
B01 Varicella [chickenpox]	0.000	0.995	0.005
B06 Rubella [German measles]	0.000	0.995	0.005
B05 Measles	0.000	0.995	0.005
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.000	0.995	0.005
B04 Monkeypox	0.000	0.995	0.005
B03 Smallpox	0.000	0.995	0.005
B00.9 Herpesviral infection, unspecified	0.000	0.995	0.005
S02.60 Fracture of mandible (closed)	0.000	0.995	0.005
B00.8 Other forms of herpesviral infection	0.000	0.995	0.005
B00.7 Disseminated herpesviral disease	0.000	0.995	0.005
B00.3 Herpesviral meningitis	0.000	0.995	0.005
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis	0.000	0.995	0.005
B00.0 Eczema herpeticum	0.000	0.995	0.005
B01.9 Varicella without complications	0.000	0.995	0.004
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.000	0.996	0.004
A04.9 Bacterial intestinal infection, unspecified	0.000	0.996	0.004
A04.4 Other intestinal Escherichia coli infections	0.000	0.996	0.004
L05 Pilonidal cyst	0.000	0.996	0.004
H49.1 Fourth [trochlear] nerve palsy	0.004	0.996	0.000
A04.6 Enteritis due to Yersinia enterocolitica	0.000	0.996	0.004
A04.3 Enterohaemorrhagic Escherichia coli infection	0.000	0.996	0.004
A04.2 Enteroinvasive Escherichia coli infection	0.000	0.996	0.004
A04.1 Enterotoxigenic Escherichia coli infection	0.000	0.996	0.004
A04.0 Enteropathogenic Escherichia coli infection	0.000	0.996	0.004
B01.8 Varicella with other complications	0.000	0.996	0.004
B01.1 Varicella encephalitis	0.000	0.996	0.004
B01.0 Varicella meningitis	0.000	0.996	0.004
B05.9 Measles without complication	0.000	0.996	0.004
B05.8 Measles with other complications	0.000	0.996	0.004
B05.4 Measles with intestinal complications	0.000	0.996	0.004
B05.3 Measles complicated by otitis media	0.000	0.996	0.004
B05.2 Measles complicated by pneumonia	0.000	0.996	0.004
B05.1 Measles complicated by meningitis	0.000	0.996	0.004
B05.0 Measles complicated by encephalitis	0.000	0.996	0.004
B06.9 Rubella without complication	0.000	0.996	0.004
B06.8 Rubella with other complications	0.000	0.996	0.004
B06.0 Rubella with neurological complications	0.000	0.996	0.004
H49.2 Sixth [abducent] nerve palsy	0.004	0.996	0.000
H49 Paralytic strabismus	0.004	0.996	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.004	0.996	0.000
H54.0 Blindness, both eyes	0.004	0.996	0.000
B02 Zoster [herpes zoster]	0.000	0.996	0.004
B00.4 Herpesviral encephalitis	0.000	0.996	0.003
B01.2 Varicella pneumonia	0.000	0.997	0.003
B08.8 Other specified viral infections characterised by skin and mucous membrane lesions	0.000	0.997	0.003
B08.5 Enteroviral vesicular pharyngitis	0.000	0.997	0.003
B08.4 Enteroviral vesicular stomatitis with exanthem	0.000	0.997	0.003
B08.3 Erythema infectiosum [fifth disease]	0.000	0.997	0.003
B08.2 Exanthema subitum [sixth disease]	0.000	0.997	0.003
B08.0 Other orthopoxvirus infections	0.000	0.997	0.003
I42 Cardiomyopathy	0.003	0.997	0.000
A04.8 Other specified bacterial intestinal infections	0.000	0.997	0.003
H49.4 Progressive external ophthalmoplegia	0.003	0.997	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.000	0.997	0.003
H49.8 Other paralytic strabismus	0.003	0.997	0.000
B02.2 Zoster with other nervous system involvement	0.000	0.997	0.003
H49.9 Paralytic strabismus, unspecified	0.003	0.997	0.000
H49.3 Total (external) ophthalmoplegia	0.003	0.997	0.000
B02.7 Disseminated zoster	0.000	0.997	0.003
B02.1 Zoster meningitis	0.000	0.997	0.003
B02.0 Zoster encephalitis	0.000	0.997	0.003
M79.18 Myalgia (Other)	0.000	0.997	0.003
I42.6 Alcoholic cardiomyopathy	0.003	0.997	0.000
M79.19 Myalgia (Site unspecified)	0.000	0.997	0.003
Z35.5 Supervision of elderly primigravida	0.000	0.997	0.003
N81.5 Vaginal enterocele	0.003	0.997	0.000
B02.3 Zoster ocular disease	0.000	0.997	0.003
I42.7 Cardiomyopathy due to drugs and other external agents	0.003	0.997	0.000
I42.5 Other restrictive cardiomyopathy	0.003	0.997	0.000
I42.4 Endocardial fibroelastosis	0.003	0.997	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.003	0.997	0.000
I42.2 Other hypertrophic cardiomyopathy	0.003	0.997	0.000
Q38.7 Pharyngeal pouch	0.003	0.997	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.003	0.997	0.000
B02.8 Zoster with other complications	0.000	0.997	0.002
D73.3 Abscess of spleen	0.003	0.997	0.000
H49.0 Third [oculomotor] nerve palsy	0.003	0.997	0.000
A04.5 Campylobacter enteritis	0.000	0.997	0.003
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.003	0.997	0.000
H53.9 Visual disturbance, unspecified	0.000	0.997	0.003
M79.1 Myalgia	0.000	0.997	0.003
B08.1 Molluscum contagiosum	0.000	0.997	0.002
D73 Diseases of spleen	0.003	0.997	0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.003	0.997	0.000
M79.16 Myalgia (Lower leg)	0.000	0.998	0.002
M94.86 Other specified disorders of cartilage (Lower leg)	0.002	0.998	0.000
I42.8 Other cardiomyopathies	0.002	0.998	0.000
L05.9 Pilonidal cyst without abscess	0.000	0.998	0.002
S46.0 Injury of tendon of the rotator cuff of shoulder	0.002	0.998	0.000
H50.2 Vertical strabismus	0.002	0.998	0.000
M79.10 Myalgia (Multiple sites)	0.000	0.998	0.002
S01.8 Open wound of other parts of head	0.000	0.998	0.002
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium	0.002	0.998	0.000
H50.1 Divergent concomitant strabismus	0.002	0.998	0.000
K55.0 Acute vascular disorders of intestine	0.002	0.998	0.000
H50 Other strabismus	0.002	0.998	0.000
M66.34 Spontaneous rupture of flexor tendons (Hand)	0.002	0.998	0.000
H47.2 Optic atrophy	0.000	0.998	0.002
H52.0 Hypermetropia	0.002	0.998	0.000
M79.11 Myalgia (Shoulder region)	0.000	0.998	0.002
O44.0 Placenta praevia specified as without haemorrhage	0.000	0.998	0.002
K59.8 Other specified functional intestinal disorders	0.000	0.998	0.002
D73.1 Hypersplenism	0.002	0.998	0.000
S02.6 Fracture of mandible	0.000	0.998	0.002
M94.8 Other specified disorders of cartilage	0.002	0.998	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.998	0.002
D22.1 Melanocytic naevi of eyelid, including canthus	0.002	0.998	0.000
D73.4 Cyst of spleen	0.002	0.998	0.000
M79.17 Myalgia (Ankle and foot)	0.000	0.998	0.002
M79.14 Myalgia (Hand)	0.000	0.998	0.002
M79.13 Myalgia (Forearm)	0.000	0.998	0.002
M79.12 Myalgia (Upper arm)	0.000	0.998	0.002
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.002	0.998	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.002	0.998	0.000
H50.6 Mechanical strabismus	0.002	0.998	0.000
N83.1 Corpus luteum cyst	0.002	0.998	0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.998	0.002
D73.9 Disease of spleen, unspecified	0.002	0.998	0.000
D73.2 Chronic congestive splenomegaly	0.002	0.998	0.000
S73.0 Dislocation of hip	0.002	0.998	0.000
M94.88 Other specified disorders of cartilage (Other)	0.002	0.998	0.000
H50.4 Other and unspecified heterotropia	0.002	0.998	0.000
M66.3 Spontaneous rupture of flexor tendons	0.002	0.998	0.000
K59.1 Functional diarrhoea	0.000	0.998	0.002
M66.47 Spontaneous rupture of other tendons (Ankle and foot)	0.002	0.998	0.000
M79.15 Myalgia (Pelvic region and thigh)	0.000	0.998	0.002
H50.8 Other specified strabismus	0.002	0.998	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.002	0.998	0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.002	0.998	0.000
H47.3 Other disorders of optic disk	0.000	0.998	0.002
H50.3 Intermittent heterotropia	0.002	0.998	0.000
K81.0 Acute cholecystitis	0.000	0.998	0.002
S46.1 Injury of muscle and tendon of long head of biceps	0.002	0.998	0.000
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.002	0.998	0.000
S02.61 Fracture of mandible (open)	0.000	0.998	0.002
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.998	0.002
H47 Other disorders of optic [2nd] nerve and visual pathways	0.000	0.998	0.002
K35-K38 Diseases of appendix	0.002	0.998	0.000
M66.31 Spontaneous rupture of flexor tendons (Shoulder region)	0.002	0.998	0.000
M66.4 Spontaneous rupture of other tendons	0.002	0.998	0.000
M94.89 Other specified disorders of cartilage (Site unspecified)	0.002	0.998	0.000
M94.84 Other specified disorders of cartilage (Hand)	0.002	0.998	0.000
M94.83 Other specified disorders of cartilage (Forearm)	0.002	0.998	0.000
M94.82 Other specified disorders of cartilage (Upper arm)	0.002	0.998	0.000
M94.81 Other specified disorders of cartilage (Shoulder region)	0.002	0.998	0.000
M94.80 Other specified disorders of cartilage (Multiple sites)	0.002	0.998	0.000
M11.2 Other chondrocalcinosis	0.000	0.998	0.002
M66.2 Spontaneous rupture of extensor tendons	0.002	0.998	0.000
O21.0 Mild hyperemesis gravidarum	0.000	0.998	0.002
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.002	0.998	0.000
H51 Other disorders of binocular movement	0.002	0.998	0.000
D73.8 Other diseases of spleen	0.002	0.998	0.000
H54.1 Blindness, one eye, low vision, other eye	0.002	0.998	0.000
M51.8 Other specified intervertebral disk disorders	0.002	0.998	0.000
H54 Blindness and low vision	0.002	0.998	0.000
M66.39 Spontaneous rupture of flexor tendons (Site unspecified)	0.002	0.998	0.000
M66.38 Spontaneous rupture of flexor tendons (Other)	0.002	0.998	0.000
M66.37 Spontaneous rupture of flexor tendons (Ankle and foot)	0.002	0.998	0.000
M66.36 Spontaneous rupture of flexor tendons (Lower leg)	0.002	0.998	0.000
M66.35 Spontaneous rupture of flexor tendons (Pelvic region and thigh)	0.002	0.998	0.000
M66.33 Spontaneous rupture of flexor tendons (Forearm)	0.002	0.998	0.000
M66.32 Spontaneous rupture of flexor tendons (Upper arm)	0.002	0.998	0.000
M66.30 Spontaneous rupture of flexor tendons (Multiple sites)	0.002	0.998	0.000
I42.9 Cardiomyopathy, unspecified	0.002	0.998	0.000
M66 Spontaneous rupture of synovium and tendon	0.002	0.998	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.002	0.998	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.002	0.998	0.000
B02.9 Zoster without complication	0.000	0.998	0.002
S62.20 Fracture of first metacarpal bone (closed)	0.002	0.998	0.000
H50.9 Strabismus, unspecified	0.002	0.998	0.000
H54.2 Low vision, both eyes	0.002	0.998	0.000
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns	0.002	0.998	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.002	0.998	0.000
M25.76 Osteophyte (Lower leg)	0.002	0.998	0.000
M66.49 Spontaneous rupture of other tendons (Site unspecified)	0.001	0.998	0.000
M66.48 Spontaneous rupture of other tendons (Other)	0.001	0.998	0.000
M66.45 Spontaneous rupture of other tendons (Pelvic region and thigh)	0.001	0.998	0.000
M66.44 Spontaneous rupture of other tendons (Hand)	0.001	0.998	0.000
M66.43 Spontaneous rupture of other tendons (Forearm)	0.001	0.998	0.000
M66.42 Spontaneous rupture of other tendons (Upper arm)	0.001	0.998	0.000
M66.41 Spontaneous rupture of other tendons (Shoulder region)	0.001	0.998	0.000
M66.40 Spontaneous rupture of other tendons (Multiple sites)	0.001	0.998	0.000
C48.0 Retroperitoneum	0.002	0.998	0.000
H47.7 Disorder of visual pathways, unspecified	0.000	0.998	0.001
H47.6 Disorders of visual cortex	0.000	0.998	0.001
H47.5 Disorders of other visual pathways	0.000	0.998	0.001
H47.4 Disorders of optic chiasm	0.000	0.998	0.001
H47.1 Papilloedema, unspecified	0.000	0.998	0.002
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.002	0.998	0.000
M11.29 Other chondrocalcinosis (Site unspecified)	0.000	0.998	0.001
M11.28 Other chondrocalcinosis (Other)	0.000	0.998	0.001
M11.27 Other chondrocalcinosis (Ankle and foot)	0.000	0.998	0.001
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.000	0.998	0.001
M11.24 Other chondrocalcinosis (Hand)	0.000	0.998	0.001
M11.23 Other chondrocalcinosis (Forearm)	0.000	0.998	0.001
M11.22 Other chondrocalcinosis (Upper arm)	0.000	0.998	0.001
M11.21 Other chondrocalcinosis (Shoulder region)	0.000	0.998	0.001
M11.20 Other chondrocalcinosis (Multiple sites)	0.000	0.998	0.001
M66.46 Spontaneous rupture of other tendons (Lower leg)	0.001	0.998	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.002	0.998	0.000
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.001	0.998	0.000
M66.28 Spontaneous rupture of extensor tendons-Other	0.001	0.998	0.000
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.001	0.998	0.000
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.001	0.998	0.000
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.001	0.998	0.000
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.001	0.998	0.000
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.001	0.998	0.000
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.001	0.998	0.000
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.001	0.998	0.000
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac	0.001	0.998	0.000
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar	0.001	0.998	0.000
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol	0.001	0.998	0.000
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic	0.001	0.998	0.000
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot	0.001	0.998	0.000
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical	0.001	0.998	0.000
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-	0.001	0.998	0.000
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit	0.001	0.998	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.002	0.998	0.000
H50.5 Heterophoria	0.001	0.998	0.000
H51.9 Disorder of binocular movement, unspecified	0.001	0.998	0.000
H51.8 Other specified disorders of binocular movement	0.001	0.998	0.000
H51.2 Internuclear ophthalmoplegia	0.001	0.998	0.000
H51.1 Convergence insufficiency and excess	0.001	0.998	0.000
H51.0 Palsy of conjugate gaze	0.001	0.998	0.000
H54.5 Low vision, one eye	0.001	0.998	0.000
H54.3 Unqualified visual loss, both eyes	0.001	0.998	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.000	0.998	0.002
C48.2 Peritoneum, unspecified	0.001	0.998	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.001	0.998	0.000
M66.1 Rupture of synovium	0.001	0.998	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.000	0.998	0.001
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.001	0.998	0.000
S46.3 Injury of muscle and tendon of triceps	0.001	0.998	0.000
K36 Other appendicitis	0.001	0.998	0.000
H50.0 Convergent concomitant strabismus	0.001	0.998	0.000
M66.0 Rupture of popliteal cyst	0.001	0.998	0.000
Q38.1 Ankyloglossia	0.001	0.998	0.000
H54.6 Unqualified visual loss, one eye	0.001	0.999	0.000
I50.1 Left ventricular failure	0.001	0.999	0.000
T78.4 Allergy, unspecified	0.001	0.999	0.000
Z35.8 Supervision of other high-risk pregnancies	0.000	0.999	0.001
D73.5 Infarction of spleen	0.001	0.999	0.000
Z35 Supervision of high-risk pregnancy	0.000	0.999	0.001
H54.4 Blindness, one eye	0.001	0.999	0.000
X59.3 Sports and athletics area	0.001	0.999	0.000
Q38.8 Other congenital malformations of pharynx	0.001	0.999	0.000
Q38.6 Other congenital malformations of mouth	0.001	0.999	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.001	0.999	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.001	0.999	0.000
Q38.3 Other congenital malformations of tongue	0.001	0.999	0.000
Q38.2 Macroglossia	0.001	0.999	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.001	0.999	0.000
H54.9 Unspecified visual impairment (binocular)	0.001	0.999	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.000	0.999	0.001
E10.2 With renal complications	0.001	0.999	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.000	0.999	0.001
K55.9 Vascular disorder of intestine, unspecified	0.001	0.999	0.000
M25.78 Osteophyte (Other)	0.001	0.999	0.000
G81.9 Hemiplegia, unspecified	0.001	0.999	0.000
M66.19 Rupture of synovium (Site unspecified)	0.001	0.999	0.000
M66.18 Rupture of synovium (Other)	0.001	0.999	0.000
M66.17 Rupture of synovium (Ankle and foot)	0.001	0.999	0.000
M66.16 Rupture of synovium (Lower leg)	0.001	0.999	0.000
M66.15 Rupture of synovium (Pelvic region and thigh)	0.001	0.999	0.000
M66.14 Rupture of synovium (Hand)	0.001	0.999	0.000
M66.13 Rupture of synovium (Forearm)	0.001	0.999	0.000
M66.12 Rupture of synovium (Upper arm)	0.001	0.999	0.000
M66.11 Rupture of synovium (Shoulder region)	0.001	0.999	0.000
M66.10 Rupture of synovium (Multiple sites)	0.001	0.999	0.000
M66.59 Spontaneous rupture of unspecified tendon (Site unspecified)	0.001	0.999	0.000
M66.58 Spontaneous rupture of unspecified tendon (Other)	0.001	0.999	0.000
M66.57 Spontaneous rupture of unspecified tendon (Ankle and foot)	0.001	0.999	0.000
M66.56 Spontaneous rupture of unspecified tendon (Lower leg)	0.001	0.999	0.000
M66.55 Spontaneous rupture of unspecified tendon (Pelvic region and thigh)	0.001	0.999	0.000
M66.54 Spontaneous rupture of unspecified tendon (Hand)	0.001	0.999	0.000
M66.53 Spontaneous rupture of unspecified tendon (Forearm)	0.001	0.999	0.000
M66.52 Spontaneous rupture of unspecified tendon (Upper arm)	0.001	0.999	0.000
M66.51 Spontaneous rupture of unspecified tendon (Shoulder region)	0.001	0.999	0.000
M66.50 Spontaneous rupture of unspecified tendon (Multiple sites)	0.001	0.999	0.000
M66.09 Rupture of popliteal cyst-Site unspec	0.001	0.999	0.000
M66.08 Rupture of popliteal cyst-Other	0.001	0.999	0.000
M66.07 Rupture of popliteal cyst-Ankle/foot	0.001	0.999	0.000
M66.05 Rupture of popliteal cyst-Pelvic/thigh	0.001	0.999	0.000
M66.04 Rupture of popliteal cyst-Hand	0.001	0.999	0.000
M66.03 Rupture of popliteal cyst-Forearm	0.001	0.999	0.000
M66.02 Rupture of popliteal cyst-Upper arm	0.001	0.999	0.000
M66.01 Rupture of popliteal cyst-Shldr region	0.001	0.999	0.000
M66.00 Rupture of popliteal cyst-Mult sites	0.001	0.999	0.000
M94.09 Chondrocostal junction syndrome [Tietze]-Site unspec	0.001	0.999	0.000
M10.96 Gout, unspecified (Lower leg)	0.000	0.999	0.001
S80.1 Contusion of other and unspecified parts of lower leg	0.000	0.999	0.001
M19.97 Arthrosis, unspecified (Ankle and foot)	0.000	0.999	0.001
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
Z35.7 Supervision of high-risk pregnancy due to social problems	0.000	0.999	0.001
Z35.6 Supervision of very young primigravida	0.000	0.999	0.001
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.000	0.999	0.001
Q24.8 Other specified congenital malformations of heart	0.001	0.999	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.001	0.999	0.000
M66.06 Rupture of popliteal cyst-Lower leg	0.001	0.999	0.000
M94.0 Chondrocostal junction syndrome [Tietze]	0.001	0.999	0.000
H52 Disorders of refraction and accommodation	0.001	0.999	0.000
I87.8 Other specified disorders of veins	0.000	0.999	0.001
Q21.1 Atrial septal defect	0.001	0.999	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.001	0.999	0.000
G91.1 Obstructive hydrocephalus	0.000	0.999	0.001
K72.0 Acute and subacute hepatic failure	0.001	0.999	0.000
S80.8 Other superficial injuries of lower leg	0.000	0.999	0.001
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.999	0.001
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.001	0.999	0.000
G81.1 Spastic hemiplegia	0.001	0.999	0.000
K55.8 Other vascular disorders of intestine	0.001	0.999	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.001	0.999	0.000
M25.79 Osteophyte (Site unspecified)	0.001	0.999	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.000	0.999	0.001
E07.9 Disorder of thyroid, unspecified	0.000	0.999	0.001
J11.1 Influenza with other respiratory manifestations, virus not identified	0.000	0.999	0.001
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.001	0.999	0.000
K38 Other diseases of appendix	0.001	0.999	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.000	0.999	0.001
H52.6 Other disorders of refraction	0.001	0.999	0.000
H52.5 Disorders of accommodation	0.001	0.999	0.000
H52.4 Presbyopia	0.001	0.999	0.000
K59.9 Functional intestinal disorder, unspecified	0.000	0.999	0.001
X59.4 Street and highway	0.001	0.999	0.000
M94 Other disorders of cartilage	0.001	0.999	0.000
M25.72 Osteophyte (Upper arm)	0.001	0.999	0.000
M94.08 Chondrocostal junction syndrome [Tietze]-Other	0.001	0.999	0.000
M94.07 Chondrocostal junction syndrome [Tietze]-Ankle/foot	0.001	0.999	0.000
M94.06 Chondrocostal junction syndrome [Tietze]-Lower leg	0.001	0.999	0.000
M94.05 Chondrocostal junction syndrome [Tietze]-Pelvic/thigh	0.001	0.999	0.000
M94.04 Chondrocostal junction syndrome [Tietze]-Hand	0.001	0.999	0.000
M94.03 Chondrocostal junction syndrome [Tietze]-Forearm	0.001	0.999	0.000
M94.02 Chondrocostal junction syndrome [Tietze]-Upper arm	0.001	0.999	0.000
M94.01 Chondrocostal junction syndrome [Tietze]-Shldr region	0.001	0.999	0.000
M94.00 Chondrocostal junction syndrome [Tietze]-Mult sites	0.001	0.999	0.000
T78.8 Other adverse effects, not elsewhere classified	0.001	0.999	0.000
K55 Vascular disorders of intestine	0.001	0.999	0.000
D86.0 Sarcoidosis of lung	0.000	0.999	0.001
K55.1 Chronic vascular disorders of intestine	0.001	0.999	0.000
M25.7 Osteophyte	0.001	0.999	0.000
N41.0 Acute prostatitis	0.001	0.999	0.000
N60.2 Fibroadenosis of breast	0.000	0.999	0.001
H46 Optic neuritis	0.000	0.999	0.001
C48.8 Overlapping lesion of retroperitoneum and peritoneum	0.001	0.999	0.000
D58.0 Hereditary spherocytosis	0.001	0.999	0.000
G44.0 Cluster headache syndrome	0.001	0.999	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.001	0.999	0.000
T78.9 Adverse effect, unspecified	0.001	0.999	0.000
V23.4 Driver injured in traffic accident	0.001	0.999	0.000
X59.2 School, other institution and public administrative area	0.001	0.999	0.000
X68.9 Unspecified place	0.000	0.999	0.001
S82.31 Fracture of lower end of tibia (open)	0.000	0.999	0.001
E10.5 With peripheral circulatory complications	0.001	0.999	0.000
G44.3 Chronic posttraumatic headache	0.001	0.999	0.000
H52.7 Disorder of refraction, unspecified	0.001	0.999	0.000
K38.3 Fistula of appendix	0.001	0.999	0.000
K38.2 Diverticulum of appendix	0.001	0.999	0.000
K38.0 Hyperplasia of appendix	0.001	0.999	0.000
M94.3 Chondrolysis	0.001	0.999	0.000
M94.1 Relapsing polychondritis	0.001	0.999	0.000
Q12.0 Congenital cataract	0.000	0.999	0.001
Z35.4 Supervision of pregnancy with grand multiparity	0.000	0.999	0.001
M25.73 Osteophyte (Forearm)	0.001	0.999	0.000
M25.70 Osteophyte (Multiple sites)	0.001	0.999	0.000
E20.9 Hypoparathyroidism, unspecified	0.001	0.999	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.999	0.001
X59 Exposure to unspecified factor	0.001	0.999	0.000
M86.98 Osteomyelitis, unspecified (Other)	0.001	0.999	0.000
C44.1 Skin of eyelid, including canthus	0.000	0.999	0.001
D86.1 Sarcoidosis of lymph nodes	0.000	0.999	0.001
K14.8 Other diseases of tongue	0.000	0.999	0.001
T75.4 Effects of electric current	0.001	0.999	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.000	0.999	0.001
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M94.19 Relapsing polychondritis (Site unspecified)	0.001	0.999	0.000
M94.18 Relapsing polychondritis (Other)	0.001	0.999	0.000
M94.17 Relapsing polychondritis (Ankle and foot)	0.001	0.999	0.000
M94.16 Relapsing polychondritis (Lower leg)	0.001	0.999	0.000
M94.15 Relapsing polychondritis (Pelvic region and thigh)	0.001	0.999	0.000
M94.14 Relapsing polychondritis (Hand)	0.001	0.999	0.000
M94.13 Relapsing polychondritis (Forearm)	0.001	0.999	0.000
M94.12 Relapsing polychondritis (Upper arm)	0.001	0.999	0.000
M94.11 Relapsing polychondritis (Shoulder region)	0.001	0.999	0.000
M94.10 Relapsing polychondritis (Multiple sites)	0.001	0.999	0.000
M94.39 Chondrolysis (Site unspecified)	0.001	0.999	0.000
M94.38 Chondrolysis (Other)	0.001	0.999	0.000
M94.37 Chondrolysis (Ankle and foot)	0.001	0.999	0.000
M94.36 Chondrolysis (Lower leg)	0.001	0.999	0.000
M94.35 Chondrolysis (Pelvic region and thigh)	0.001	0.999	0.000
M94.34 Chondrolysis (Hand)	0.001	0.999	0.000
M94.33 Chondrolysis (Forearm)	0.001	0.999	0.000
M94.32 Chondrolysis (Upper arm)	0.001	0.999	0.000
M94.31 Chondrolysis (Shoulder region)	0.001	0.999	0.000
M94.30 Chondrolysis (Multiple sites)	0.001	0.999	0.000
L40.9 Psoriasis, unspecified	0.001	0.999	0.000
L60.0 Ingrowing nail	0.001	0.999	0.000
S99.9 Unspecified injury of ankle and foot	0.000	0.999	0.001
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.001	0.999	0.000
Y48.3 Local anaesthetics	0.001	0.999	0.000
G81 Hemiplegia	0.001	0.999	0.000
S32.40 Fracture of acetabulum (closed)	0.001	0.999	0.000
M94.9 Disorder of cartilage, unspecified	0.001	0.999	0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
O75.0 Maternal distress during labour and delivery	0.001	0.999	0.000
S73.1 Sprain and strain of hip	0.001	0.999	0.000
X59.9 Unspecified place	0.001	0.999	0.000
X59.8 Other specified place	0.001	0.999	0.000
X59.0 Home	0.001	0.999	0.000
X59.7 Farm	0.001	0.999	0.000
X59.6 Industrial and construction area	0.001	0.999	0.000
X59.5 Trade and service area	0.001	0.999	0.000
X59.1 Residential institution	0.001	0.999	0.000
M24.07 Loose body in joint (Ankle and foot)	0.000	0.999	0.001
M53.99 Dorsopathy, unspecified (Site unspecified)	0.001	0.999	0.000
S36.10 Injury of liver or gallbladder (without open wound into cavity)	0.000	0.999	0.001
D86.8 Sarcoidosis of other and combined sites	0.000	0.999	0.001
E88.9 Metabolic disorder, unspecified	0.001	0.999	0.000
G81.0 Flaccid hemiplegia	0.001	0.999	0.000
K38.1 Appendicular concretions	0.001	0.999	0.000
T43.6 Psychostimulants with abuse potential	0.000	0.999	0.001
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.999	0.001
T78.0 Anaphylactic shock due to adverse food reaction	0.001	0.999	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.001	0.999	0.000
T78 Adverse effects, not elsewhere classified	0.001	0.999	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.000	0.999	0.001
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.999	0.001
M94.99 Disorder of cartilage, unspecified (Site unspecified)	0.001	0.999	0.000
M94.98 Disorder of cartilage, unspecified (Other)	0.001	0.999	0.000
M94.97 Disorder of cartilage, unspecified (Ankle and foot)	0.001	0.999	0.000
M94.95 Disorder of cartilage, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M94.94 Disorder of cartilage, unspecified (Hand)	0.001	0.999	0.000
M94.93 Disorder of cartilage, unspecified (Forearm)	0.001	0.999	0.000
M94.92 Disorder of cartilage, unspecified (Upper arm)	0.001	0.999	0.000
M94.91 Disorder of cartilage, unspecified (Shoulder region)	0.001	0.999	0.000
M94.90 Disorder of cartilage, unspecified (Multiple sites)	0.001	0.999	0.000
X59.09 Exposure to unspecified factor causing fracture; Unspecified place;	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations