TreeWAS – Variant ID: rs35106244

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K80 Cholelithiasis	1.000	0.000	0.000
K80.2 Calculus of gallbladder without cholecystitis	1.000	0.000	0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	1.000	0.000	0.000
K26 Duodenal ulcer	1.000	0.000	0.000
K80.1 Calculus of gallbladder with other cholecystitis	1.000	0.000	0.000
K20-K31 Diseases of oesophagus, stomach and duodenum	1.000	0.000	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	1.000	0.000	0.000
K29 Gastritis and duodenitis	1.000	0.000	0.000
Chapter XI Diseases of the digestive system	0.999	0.001	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.997	0.003	0.000
K29.8 Duodenitis	0.995	0.005	0.000
K82 Other diseases of gallbladder	0.989	0.011	0.000
K65-K67 Diseases of peritoneum	0.987	0.013	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.970	0.030	0.000
K29.4 Chronic atrophic gastritis	0.967	0.033	0.000
K65 Peritonitis	0.955	0.045	0.000
K29.0 Acute haemorrhagic gastritis	0.955	0.045	0.000
K83 Other diseases of biliary tract	0.953	0.047	0.000
K82.4 Cholesterolosis of gallbladder	0.949	0.051	0.000
E78.0 Pure hypercholesterolaemia	0.942	0.058	0.000
I10 Essential (primary) hypertension	0.928	0.072	0.000
K82.9 Disease of gallbladder, unspecified	0.921	0.079	0.000
K26.7 Chronic without haemorrhage or perforation	0.920	0.080	0.000
K66 Other disorders of peritoneum	0.915	0.084	0.000
K83.1 Obstruction of bile duct	0.909	0.091	0.000
K27 Peptic ulcer, site unspecified	0.905	0.095	0.000
K29.5 Chronic gastritis, unspecified	0.898	0.102	0.000
K82.8 Other specified diseases of gallbladder	0.895	0.105	0.000
K65.8 Other peritonitis	0.887	0.113	0.000
K70-K77 Diseases of liver	0.882	0.118	0.000
K66.0 Peritoneal adhesions	0.875	0.125	0.000
K70 Alcoholic liver disease	0.868	0.132	0.000
K26.4 Chronic or unspecified with haemorrhage	0.867	0.133	0.000
K83.0 Cholangitis	0.866	0.134	0.000
K70.3 Alcoholic cirrhosis of liver	0.858	0.142	0.000
K26.1 Acute with perforation	0.851	0.149	0.000
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.848	0.152	0.000
K29.3 Chronic superficial gastritis	0.845	0.155	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.834	0.166	0.000
K80.8 Other cholelithiasis	0.821	0.179	0.000
K65.0 Acute peritonitis	0.818	0.182	0.000
K23 Disorders of oesophagus in diseases classified elsewhere	0.817	0.183	0.000
K66.8 Other specified disorders of peritoneum	0.809	0.191	0.000
K83.5 Biliary cyst	0.786	0.214	0.000
K29.2 Alcoholic gastritis	0.782	0.218	0.000
K65.9 Peritonitis, unspecified	0.778	0.222	0.000
K73 Chronic hepatitis, not elsewhere classified	0.763	0.237	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.763	0.237	0.000
K27.7 Chronic without haemorrhage or perforation	0.746	0.254	0.000
K74 Fibrosis and cirrhosis of liver	0.745	0.255	0.000
K25 Gastric ulcer	0.733	0.267	0.000
K26.2 Acute with both haemorrhage and perforation	0.722	0.277	0.000
K83.9 Disease of biliary tract, unspecified	0.718	0.282	0.000
K80.3 Calculus of bile duct with cholangitis	0.717	0.283	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.717	0.283	0.000
K29.9 Gastroduodenitis, unspecified	0.717	0.283	0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.708	0.292	0.000
K27.4 Chronic or unspecified with haemorrhage	0.705	0.295	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.703	0.297	0.000
K29.1 Other acute gastritis	0.690	0.310	0.000
K28 Gastrojejunal ulcer	0.687	0.313	0.000
K23.8 Disorders of oesophagus in other diseases classified elsewhere	0.687	0.313	0.000
K83.2 Perforation of bile duct	0.684	0.316	0.000
K25.3 Acute without haemorrhage or perforation	0.682	0.318	0.000
K70.9 Alcoholic liver disease, unspecified	0.671	0.329	0.000
K82.3 Fistula of gallbladder	0.657	0.343	0.000
K27.3 Acute without haemorrhage or perforation	0.650	0.350	0.000
K27.6 Chronic or unspecified with both haemorrhage and perforation	0.649	0.351	0.000
K27.5 Chronic or unspecified with perforation	0.649	0.351	0.000
K27.2 Acute with both haemorrhage and perforation	0.649	0.351	0.000
K27.1 Acute with perforation	0.649	0.351	0.000
K27.0 Acute with haemorrhage	0.649	0.351	0.000
K26.5 Chronic or unspecified with perforation	0.648	0.352	0.000
K82.0 Obstruction of gallbladder	0.639	0.361	0.000
K77 Liver disorders in diseases classified elsewhere	0.632	0.368	0.000
K74.5 Biliary cirrhosis, unspecified	0.628	0.372	0.000
K82.1 Hydrops of gallbladder	0.627	0.373	0.000
K82.2 Perforation of gallbladder	0.625	0.374	0.000
K73.9 Chronic hepatitis, unspecified	0.621	0.379	0.000
K74.0 Hepatic fibrosis	0.614	0.385	0.000
I80 Phlebitis and thrombophlebitis	0.608	0.392	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.597	0.403	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.595	0.405	0.000
K70.4 Alcoholic hepatic failure	0.593	0.407	0.000
K70.0 Alcoholic fatty liver	0.592	0.408	0.000
K66.9 Disorder of peritoneum, unspecified	0.590	0.410	0.000
K23.1 Megaoesophagus in Chagas' disease	0.586	0.414	0.000
K23.0 Tuberculous oesophagitis	0.586	0.414	0.000
K83.3 Fistula of bile duct	0.583	0.417	0.000
K83.4 Spasm of sphincter of Oddi	0.577	0.423	0.000
K26.0 Acute with haemorrhage	0.575	0.425	0.000
I10-I15 Hypertensive diseases	0.574	0.426	0.000
K26.3 Acute without haemorrhage or perforation	0.571	0.429	0.000
K74.1 Hepatic sclerosis	0.557	0.443	0.000
K25.5 Chronic or unspecified with perforation	0.557	0.443	0.000
K25.0 Acute with haemorrhage	0.552	0.448	0.000
K74.6 Other and unspecified cirrhosis of liver	0.549	0.451	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.547	0.453	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.547	0.453	0.000
K74.4 Secondary biliary cirrhosis	0.534	0.466	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.534	0.466	0.000
K70.1 Alcoholic hepatitis	0.527	0.473	0.000
K25.4 Chronic or unspecified with haemorrhage	0.526	0.474	0.000
K25.6 Chronic or unspecified with both haemorrhage and perforation	0.526	0.474	0.000
K25.2 Acute with both haemorrhage and perforation	0.526	0.474	0.000
K25.1 Acute with perforation	0.526	0.474	0.000
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.514	0.486	0.000
K87.1 Disorders of pancreas in diseases classified elsewhere	0.514	0.486	0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.514	0.486	0.000
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere	0.507	0.492	0.000
K67.3 Tuberculous peritonitis	0.507	0.492	0.000
K67.2 Syphilitic peritonitis	0.507	0.492	0.000
K67.1 Gonococcal peritonitis	0.507	0.492	0.000
K67.0 Chlamydial peritonitis	0.507	0.492	0.000
K85 Acute pancreatitis	0.495	0.504	0.000
K28.7 Chronic without haemorrhage or perforation	0.493	0.507	0.000
K28.6 Chronic or unspecified with both haemorrhage and perforation	0.493	0.507	0.000
K28.5 Chronic or unspecified with perforation	0.493	0.507	0.000
K28.4 Chronic or unspecified with haemorrhage	0.493	0.507	0.000
K28.3 Acute without haemorrhage or perforation	0.493	0.507	0.000
K28.2 Acute with both haemorrhage and perforation	0.493	0.507	0.000
K28.1 Acute with perforation	0.493	0.507	0.000
K28.0 Acute with haemorrhage	0.493	0.507	0.000
K71 Toxic liver disease	0.487	0.513	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.486	0.514	0.000
K35-K38 Diseases of appendix	0.482	0.518	0.000
I83 Varicose veins of lower extremities	0.477	0.523	0.000
I15 Secondary hypertension	0.472	0.528	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.471	0.529	0.000
Chapter IX Diseases of the circulatory system	0.469	0.531	0.000
K28.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.463	0.537	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.460	0.540	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.459	0.541	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.453	0.547	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.453	0.547	0.000
I13 Hypertensive heart and renal disease	0.428	0.572	0.000
K72 Hepatic failure, not elsewhere classified	0.427	0.573	0.000
K25.7 Chronic without haemorrhage or perforation	0.418	0.582	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.415	0.585	0.000
I88 Nonspecific lymphadenitis	0.410	0.590	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.402	0.598	0.000
I60-I69 Cerebrovascular diseases	0.401	0.599	0.000
K74.3 Primary biliary cirrhosis	0.401	0.599	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.397	0.603	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.395	0.605	0.000
K85.9 Acute pancreatitis, unspecified	0.395	0.605	0.000
I15.9 Seconday hypertension, unspecified	0.392	0.607	0.000
K40-K46 Hernia	0.387	0.613	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.387	0.613	0.000
K50-K52 Noninfective enteritis and colitis	0.384	0.616	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.378	0.622	0.000
K85.8 Other acute pancreatitis	0.375	0.624	0.000
I61 Intracerebral haemorrhage	0.372	0.628	0.000
I15.2 Hypertension secondary to endocrine disorders	0.368	0.632	0.000
I69 Sequelae of cerebrovascular disease	0.361	0.639	0.000
K36 Other appendicitis	0.356	0.644	0.000
K85.3 Drug-induced acute pancreatitis	0.355	0.645	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.351	0.649	0.000
I26 Pulmonary embolism	0.351	0.649	0.000
K83.8 Other specified diseases of biliary tract	0.350	0.650	0.000
K71.9 Toxic liver disease, unspecified	0.349	0.651	0.000
K71.8 Toxic liver disease with other disorders of liver	0.349	0.651	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.349	0.651	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.349	0.651	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.349	0.651	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.349	0.651	0.000
K71.2 Toxic liver disease with acute hepatitis	0.349	0.651	0.000
I15.1 Hypertension secondary to other renal disorders	0.347	0.653	0.000
K43 Ventral hernia	0.347	0.653	0.000
I15.8 Other secondary hypertension	0.341	0.659	0.000
K38 Other diseases of appendix	0.339	0.661	0.000
I69.3 Sequelae of cerebral infarction	0.338	0.662	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.337	0.663	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.337	0.663	0.000
I60 Subarachnoid haemorrhage	0.337	0.663	0.000
I85 Oesophageal varices	0.337	0.663	0.000
K71.0 Toxic liver disease with cholestasis	0.336	0.664	0.000
K43.9 Ventral hernia without obstruction or gangrene	0.334	0.666	0.000
K50 Crohn's disease [regional enteritis]	0.330	0.670	0.000
K85.0 Idiopathic acute pancreatitis	0.329	0.670	0.000
I00-I02 Acute rheumatic fever	0.328	0.672	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.326	0.674	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.322	0.678	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.318	0.682	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.317	0.683	0.000
K41 Femoral hernia	0.316	0.684	0.000
K90-K93 Other diseases of the digestive system	0.315	0.685	0.000
I28 Other diseases of pulmonary vessels	0.313	0.687	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.307	0.692	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.307	0.693	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.307	0.693	0.000
I88.8 Other nonspecific lymphadenitis	0.306	0.694	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.306	0.694	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.304	0.695	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.303	0.696	0.000
K80.4 Calculus of bile duct with cholecystitis	0.302	0.698	0.000
I15.0 Renovascular hypertension	0.301	0.699	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.300	0.700	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.299	0.701	0.000
K50.1 Crohn's disease of large intestine	0.295	0.705	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.294	0.706	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.293	0.707	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.292	0.707	0.001
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.292	0.708	0.000
K35 Acute appendicitis	0.290	0.710	0.000
I61.8 Other intracerebral haemorrhage	0.289	0.711	0.000
K46 Unspecified abdominal hernia	0.289	0.711	0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.289	0.711	0.000
K72.0 Acute and subacute hepatic failure	0.286	0.714	0.000
I62 Other nontraumatic intracranial haemorrhage	0.286	0.714	0.000
I11 Hypertensive heart disease	0.285	0.715	0.000
K66.1 Haemoperitoneum	0.280	0.718	0.002
I88.0 Nonspecific mesenteric lymphadenitis	0.277	0.723	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.275	0.725	0.000
I63 Cerebral infarction	0.272	0.728	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.271	0.729	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.271	0.729	0.000
K50.8 Other Crohn's disease	0.270	0.730	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.269	0.731	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.266	0.734	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.264	0.736	0.000
I65.1 Occlusion and stenosis of basilar artery	0.262	0.738	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.262	0.738	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.261	0.739	0.000
K35.2 Acute appendicitis with generalized peritonitis	0.258	0.742	0.000
I85.9 Oesophageal varices without bleeding	0.258	0.742	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.255	0.745	0.000
K50.9 Crohn's disease, unspecified	0.254	0.746	0.000
K38.0 Hyperplasia of appendix	0.253	0.747	0.000
I28.8 Other specified diseases of pulmonary vessels	0.253	0.747	0.000
K72.1 Chronic hepatic failure	0.253	0.747	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.252	0.748	0.000
I87 Other disorders of veins	0.252	0.748	0.000
K43.7 Other and unspecified ventral hernia with gangrene	0.249	0.751	0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene	0.249	0.751	0.000
K43.5 Parastomal hernia without obstruction or gangrene	0.249	0.751	0.000
K43.4 Parastomal hernia with gangrene	0.249	0.751	0.000
K43.3 Parastomal hernia with obstruction, without gangrene	0.249	0.751	0.000
K43.2 Incisional hernia without obstruction or gangrene	0.249	0.751	0.000
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.247	0.753	0.000
K38.1 Appendicular concretions	0.247	0.753	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.247	0.753	0.000
K35.8 Acute appendicitis, other and unspecified	0.245	0.755	0.000
N13 Obstructive and reflux uropathy	0.244	0.756	0.000
K38.3 Fistula of appendix	0.243	0.757	0.000
K38.2 Diverticulum of appendix	0.243	0.757	0.000
K38.9 Disease of appendix, unspecified	0.243	0.757	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.242	0.758	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.242	0.758	0.000
N10-N16 Renal tubulo-interstitial diseases	0.242	0.758	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.242	0.758	0.000
K43.1 Ventral hernia with gangrene	0.241	0.759	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.240	0.760	0.000
I82 Other venous embolism and thrombosis	0.240	0.760	0.000
K85.1 Biliary acute pancreatitis	0.239	0.761	0.000
K45 Other abdominal hernia	0.238	0.762	0.000
K29.6 Other gastritis	0.237	0.763	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.237	0.763	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.236	0.764	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.236	0.764	0.000
I02 Rheumatic chorea	0.235	0.765	0.000
I01 Rheumatic fever with heart involvement	0.235	0.765	0.000
N13.8 Other obstructive and reflux uropathy	0.235	0.765	0.000
K72.9 Hepatic failure, unspecified	0.234	0.766	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.233	0.766	0.000
I62.1 Nontraumatic extradural haemorrhage	0.231	0.769	0.000
I60.8 Other subarachnoid haemorrhage	0.230	0.770	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.230	0.770	0.000
I00 Rheumatic fever without mention of heart involvement	0.227	0.773	0.000
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.227	0.773	0.000
K41.1 Bilateral femoral hernia, with gangrene	0.227	0.773	0.000
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.227	0.773	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.226	0.774	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.225	0.775	0.000
I28.1 Aneurysm of pulmonary artery	0.224	0.776	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.224	0.776	0.000
I86 Varicose veins of other sites	0.224	0.776	0.000
K85.2 Alcohol-induced acute pancreatitis	0.223	0.776	0.001
K38.8 Other specified diseases of appendix	0.218	0.782	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.217	0.783	0.000
I68.0 Cerebral amyloid angiopathy	0.215	0.784	0.000
N13.6 Pyonephrosis	0.215	0.785	0.000
N11 Chronic tubulo-interstitial nephritis	0.215	0.785	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.214	0.786	0.000
K37 Unspecified appendicitis	0.214	0.786	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.213	0.787	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.210	0.790	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.210	0.790	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.210	0.790	0.000
I85.0 Oesophageal varices with bleeding	0.208	0.792	0.000
K46.1 Unspecified abdominal hernia with gangrene	0.207	0.793	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.206	0.794	0.000
K91.4 Colostomy and enterostomy malfunction	0.204	0.796	0.000
N10 Acute tubulo-interstitial nephritis	0.204	0.796	0.000
K35.3 Acute appendicitis with localized peritonitis	0.203	0.797	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.202	0.798	0.000
K31 Other diseases of stomach and duodenum	0.197	0.803	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.196	0.804	0.000
K44 Diaphragmatic hernia	0.196	0.804	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.196	0.804	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.195	0.804	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.195	0.804	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.195	0.805	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.193	0.806	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.193	0.807	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.193	0.807	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.193	0.807	0.000
K76 Other diseases of liver	0.190	0.810	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.190	0.810	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.189	0.811	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.189	0.811	0.000
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.189	0.811	0.000
I99 Other and unspecified disorders of circulatory system	0.188	0.812	0.000
I63.9 Cerebral infarction, unspecified	0.188	0.812	0.000
N11.1 Chronic obstructive pyelonephritis	0.184	0.816	0.000
I12 Hypertensive renal disease	0.183	0.816	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.183	0.817	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.181	0.819	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.181	0.819	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.181	0.819	0.000
I82.0 Budd-Chiari syndrome	0.181	0.819	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.181	0.819	0.000
I87.0 Postphlebitic syndrome	0.180	0.819	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.180	0.820	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.179	0.820	0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene	0.178	0.821	0.000
J98 Other respiratory disorders	0.176	0.824	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.175	0.825	0.000
J09-J18 Influenza and pneumonia	0.174	0.826	0.000
J95-J99 Other diseases of the respiratory system	0.174	0.826	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.173	0.827	0.000
N15 Other renal tubulo-interstitial diseases	0.172	0.828	0.000
I82.1 Thrombophlebitis migrans	0.172	0.828	0.000
K21 Gastro-oesophageal reflux disease	0.172	0.828	0.000
N13.3 Other and unspecified hydronephrosis	0.172	0.828	0.000
K45.1 Other specified abdominal hernia with gangrene	0.171	0.829	0.000
I89.1 Lymphangitis	0.170	0.830	0.000
I86.2 Pelvic varices	0.170	0.830	0.000
I82.2 Embolism and thrombosis of vena cava	0.169	0.830	0.000
I87.9 Disorder of vein, unspecified	0.169	0.831	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.169	0.831	0.000
I01.8 Other acute rheumatic heart disease	0.169	0.831	0.000
I01.2 Acute rheumatic myocarditis	0.169	0.831	0.000
I01.1 Acute rheumatic endocarditis	0.169	0.831	0.000
I01.0 Acute rheumatic pericarditis	0.169	0.831	0.000
I02.9 Rheumatic chorea without heart involvement	0.169	0.831	0.000
I02.0 Rheumatic chorea with heart involvement	0.169	0.831	0.000
K91.5 Postcholecystectomy syndrome	0.169	0.831	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.168	0.832	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.167	0.833	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.167	0.833	0.000
I05-I09 Chronic rheumatic heart diseases	0.167	0.833	0.000
J18 Pneumonia, organism unspecified	0.166	0.834	0.000
J18.1 Lobar pneumonia, unspecified	0.166	0.834	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.165	0.835	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.165	0.835	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.165	0.835	0.000
I98.0 Cardiovascular syphilis	0.165	0.835	0.000
J98.8 Other specified respiratory disorders	0.164	0.836	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.164	0.836	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.163	0.836	0.000
J10 Influenza due to identified influenza virus	0.163	0.837	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.162	0.838	0.000
K93.1 Megacolon in Chagas' disease	0.162	0.838	0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.162	0.838	0.000
I86.4 Gastric varices	0.162	0.838	0.000
Chapter X Diseases of the respiratory system	0.162	0.838	0.000
K75 Other inflammatory liver diseases	0.161	0.838	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.161	0.839	0.000
I86.0 Sublingual varices	0.161	0.839	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.161	0.839	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.161	0.839	0.000
K31.4 Gastric diverticulum	0.160	0.840	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.160	0.840	0.000
I86.8 Varicose veins of other specified sites	0.159	0.841	0.000
J98.1 Pulmonary collapse	0.158	0.842	0.000
K43.0 Ventral hernia with obstruction, without gangrene	0.158	0.842	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.158	0.842	0.000
J12 Viral pneumonia, not elsewhere classified	0.157	0.843	0.000
J95.8 Other postprocedural respiratory disorders	0.156	0.844	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.154	0.846	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.154	0.846	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.153	0.847	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.153	0.847	0.000
K31.2 Hourglass stricture and stenosis of stomach	0.152	0.848	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.151	0.849	0.000
J98.4 Other disorders of lung	0.151	0.849	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.151	0.849	0.000
K91.3 Postoperative intestinal obstruction	0.149	0.851	0.000
I82.3 Embolism and thrombosis of renal vein	0.149	0.851	0.000
K31.9 Disease of stomach and duodenum, unspecified	0.148	0.852	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.148	0.852	0.000
K91.1 Postgastric surgery syndromes	0.147	0.853	0.000
J15.9 Bacterial pneumonia, unspecified	0.146	0.854	0.000
I87.8 Other specified disorders of veins	0.145	0.855	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.143	0.857	0.000
K31.6 Fistula of stomach and duodenum	0.143	0.857	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.142	0.857	0.000
K76.1 Chronic passive congestion of liver	0.142	0.858	0.000
I86.3 Vulval varices	0.141	0.859	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.140	0.860	0.000
N14.3 Nephropathy induced by heavy metals	0.140	0.860	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.140	0.860	0.000
N14.0 Analgesic nephropathy	0.140	0.860	0.000
I87.1 Compression of vein	0.140	0.860	0.000
K50.0 Crohn's disease of small intestine	0.140	0.860	0.000
J98.5 Diseases of mediastinum, not elsewhere classified	0.139	0.861	0.000
I81 Portal vein thrombosis	0.138	0.862	0.000
J98.2 Interstitial emphysema	0.138	0.862	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.137	0.863	0.000
K76.5 Hepatic veno-occlusive disease	0.137	0.863	0.000
K76.4 Peliosis hepatis	0.137	0.863	0.000
K76.3 Infarction of liver	0.137	0.863	0.000
K76.2 Central haemorrhagic necrosis of liver	0.137	0.863	0.000
# Top node	0.136	0.864	0.000
J60-J70 Lung diseases due to external agents	0.136	0.864	0.000
K31.3 Pylorospasm, not elsewhere classified	0.135	0.865	0.000
N15.1 Renal and perinephric abscess	0.135	0.865	0.000
J15.5 Pneumonia due to Escherichia coli	0.135	0.865	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.133	0.867	0.000
K76.8 Other specified diseases of liver	0.133	0.867	0.000
J84 Other interstitial pulmonary diseases	0.133	0.867	0.000
K31.0 Acute dilatation of stomach	0.131	0.869	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.131	0.869	0.000
J12.9 Viral pneumonia, unspecified	0.130	0.870	0.000
J17 Pneumonia in diseases classified elsewhere	0.130	0.870	0.000
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.130	0.870	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.130	0.870	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.130	0.870	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.130	0.870	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.130	0.870	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.130	0.870	0.000
J12.2 Parainfluenza virus pneumonia	0.130	0.870	0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.129	0.871	0.000
K90 Intestinal malabsorption	0.128	0.872	0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.128	0.872	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.127	0.872	0.000
Chapter XX External causes of morbidity and mortality	0.127	0.873	0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.127	0.873	0.000
J18.0 Bronchopneumonia, unspecified	0.127	0.873	0.000
J98.3 Compensatory emphysema	0.126	0.874	0.000
I07 Rheumatic tricuspid valve diseases	0.126	0.874	0.000
I95 Hypotension	0.126	0.874	0.000
K52 Other non-infective gastro-enteritis and colitis	0.126	0.874	0.000
K44.1 Diaphragmatic hernia with gangrene	0.125	0.875	0.000
J09 Influenza due to certain identified influenza virus	0.125	0.875	0.000
J96 Respiratory failure, not elsewhere classified	0.125	0.875	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.125	0.875	0.000
J15.8 Other bacterial pneumonia	0.125	0.875	0.000
J11 Influenza, virus not identified	0.125	0.875	0.000
Chapter V Mental and behavioural disorders	0.124	0.876	0.000
I27 Other pulmonary heart diseases	0.124	0.876	0.000
N15.8 Other specified renal tubulo-interstitial diseases	0.124	0.876	0.000
N15.0 Balkan nephropathy	0.124	0.876	0.000
J69 Pneumonitis due to solids and liquids	0.123	0.877	0.000
J98.9 Respiratory disorder, unspecified	0.123	0.877	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.123	0.877	0.000
K75.0 Abscess of liver	0.123	0.877	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.123	0.877	0.000
J12.1 Respiratory syncytial virus pneumonia	0.122	0.878	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.122	0.878	0.000
I06 Rheumatic aortic valve diseases	0.122	0.878	0.000
K76.6 Portal hypertension	0.121	0.879	0.000
J95.9 Postprocedural respiratory disorder, unspecified	0.120	0.879	0.000
J95.2 Acute pulmonary insufficiency following nonthoracic surgery	0.120	0.880	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.120	0.880	0.000
J15.3 Pneumonia due to streptococcus, group B	0.120	0.880	0.000
J15.2 Pneumonia due to staphylococcus	0.120	0.880	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.120	0.880	0.000
J18.2 Hypostatic pneumonia, unspecified	0.119	0.881	0.000
J98.6 Disorders of diaphragm	0.119	0.881	0.000
F10.0 Acute intoxication	0.119	0.881	0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.118	0.882	0.000
K76.7 Hepatorenal syndrome	0.117	0.883	0.000
J69.0 Pneumonitis due to food and vomit	0.117	0.883	0.000
J10.8 Influenza with other manifestations, influenza virus identified	0.117	0.883	0.000
J95.5 Postprocedural subglottic stenosis	0.117	0.883	0.000
K75.2 Nonspecific reactive hepatitis	0.116	0.884	0.000
K75.1 Phlebitis of portal vein	0.116	0.884	0.000
J95.4 Mendelson's syndrome	0.116	0.884	0.000
J95.3 Chronic pulmonary insufficiency following surgery	0.116	0.884	0.000
J95.1 Acute pulmonary insufficiency following thoracic surgery	0.116	0.884	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.116	0.884	0.000
F10.3 Withdrawal state	0.115	0.885	0.000
Y44 Agents primarily affecting blood constituents	0.115	0.885	0.000
J18.8 Other pneumonia, organism unspecified	0.115	0.885	0.000
J84.8 Other specified interstitial pulmonary diseases	0.115	0.885	0.000
J15.4 Pneumonia due to other streptococci	0.115	0.885	0.000
F99-F99 Unspecified mental disorder	0.114	0.886	0.000
X50-X57 Overexertion, travel and privation	0.114	0.886	0.000
J81 Pulmonary oedema	0.113	0.887	0.000
X60-X84 Intentional self-harm	0.113	0.887	0.000
J12.8 Other viral pneumonia	0.113	0.887	0.000
J12.3 Human metapneumovirus pneumonia	0.113	0.887	0.000
J12.0 Adenoviral pneumonia	0.113	0.887	0.000
J67 Hypersensitivity pneumonitis due to organic dust	0.113	0.887	0.000
F80-F89 Disorders of psychological development	0.113	0.887	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.112	0.888	0.000
I27.9 Pulmonary heart disease, unspecified	0.112	0.888	0.000
J17.2 Pneumonia in mycoses	0.112	0.888	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations