TreeWAS – Variant ID: rs351855

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Y83.4 Other reconstructive surgery	0.000	0.961	0.039
R47.1 Dysarthria and anarthria	0.000	0.973	0.027
M75.4 Impingement syndrome of shoulder	0.000	0.977	0.023
M75 Shoulder lesions	0.000	0.982	0.018
M75.3 Calcific tendinitis of shoulder	0.000	0.983	0.017
M75.0 Adhesive capsulitis of shoulder	0.000	0.984	0.016
F32.1 Moderate depressive episode	0.015	0.985	0.000
M75.9 Shoulder lesion, unspecified	0.000	0.986	0.014
M75.5 Bursitis of shoulder	0.000	0.986	0.014
M75.2 Bicipital tendinitis	0.000	0.987	0.013
M75.8 Other shoulder lesions	0.000	0.987	0.013
M75.1 Rotator cuff syndrome	0.000	0.987	0.013
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.000	0.990	0.010
T39.1 4-Aminophenol derivatives	0.009	0.991	0.000
M75.81 Other shoulder lesions, right shoulder	0.000	0.991	0.008
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.000	0.992	0.008
M85.8 Other specified disorders of bone density and structure	0.000	0.993	0.007
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.000	0.993	0.007
H04.2 Epiphora	0.000	0.994	0.006
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.000	0.994	0.006
F32 Depressive episode	0.006	0.994	0.000
M85.0 Fibrous dysplasia (monostotic)	0.000	0.994	0.006
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.000	0.994	0.006
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.006	0.994	0.000
M85 Other disorders of bone density and structure	0.000	0.994	0.006
F32.8 Other depressive episodes	0.006	0.994	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.000	0.994	0.006
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.994	0.006
T39.0 Salicylates	0.006	0.994	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.000	0.995	0.005
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.000	0.995	0.005
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.000	0.995	0.005
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.005	0.995	0.000
M85.6 Other cyst of bone	0.000	0.995	0.005
M85.88 Other specified disorders of bone density and structure (Other)	0.000	0.995	0.005
N76.0 Acute vaginitis	0.000	0.995	0.005
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.000	0.995	0.005
H02.8 Other specified disorders of eyelid	0.000	0.995	0.005
R47 Speech disturbances, not elsewhere classified	0.000	0.995	0.005
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.005	0.995	0.000
N20.9 Urinary calculus, unspecified	0.005	0.995	0.000
S92.30 Fracture of metatarsal bone (closed)	0.005	0.995	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.000	0.995	0.005
Z51.8 Other specified medical care	0.000	0.995	0.005
M85.83 Other specified disorders of bone density and structure (Forearm)	0.000	0.995	0.005
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.000	0.995	0.005
M85.08 Fibrous dysplasia (monostotic) (Other)	0.000	0.995	0.005
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.000	0.995	0.005
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.000	0.995	0.005
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.000	0.995	0.005
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.000	0.995	0.005
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.000	0.995	0.005
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.000	0.995	0.005
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.000	0.995	0.005
R82.9 Other and unspecified abnormal finding in urine	0.005	0.995	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.005	0.995	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.005	0.995	0.000
Z91.5 Personal history of self-harm	0.005	0.995	0.000
T39.4 Antirheumatics, not elsewhere classified	0.004	0.995	0.000
T39.2 Pyrazolone derivatives	0.004	0.995	0.000
M85.5 Aneurysmal bone cyst	0.000	0.995	0.004
M85.3 Osteitis condensans	0.000	0.995	0.004
M85.2 Hyperostosis of skull	0.000	0.995	0.004
M85.1 Skeletal fluorosis	0.000	0.995	0.004
N76.2 Acute vulvitis	0.000	0.996	0.004
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.004	0.996	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.000	0.996	0.004
F33 Recurrent depressive disorder	0.004	0.996	0.000
F32.0 Mild depressive episode	0.004	0.996	0.000
M85.9 Disorder of bone density and structure, unspecified	0.000	0.996	0.004
M85.67 Other cyst of bone (Ankle and foot)	0.000	0.996	0.004
M85.4 Solitary bone cyst	0.000	0.996	0.004
N36.0 Urethral fistula	0.004	0.996	0.000
F30-F39 Mood [affective] disorders	0.004	0.996	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.004	0.996	0.000
J45.9 Asthma, unspecified	0.004	0.996	0.000
T43.6 Psychostimulants with abuse potential	0.004	0.996	0.000
M85.68 Other cyst of bone (Other)	0.000	0.996	0.004
M85.69 Other cyst of bone (Site unspecified)	0.000	0.996	0.004
M85.63 Other cyst of bone (Forearm)	0.000	0.996	0.004
M85.62 Other cyst of bone (Upper arm)	0.000	0.996	0.004
M85.61 Other cyst of bone (Shoulder region)	0.000	0.996	0.004
M85.60 Other cyst of bone (Multiple sites)	0.000	0.996	0.004
H02.1 Ectropion of eyelid	0.000	0.996	0.004
S92.3 Fracture of metatarsal bone	0.004	0.996	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.000	0.996	0.004
T43.3 Phenothiazine antipsychotics and neuroleptics	0.004	0.996	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.004	0.996	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.004	0.996	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
M85.66 Other cyst of bone (Lower leg)	0.000	0.996	0.004
F32.3 Severe depressive episode with psychotic symptoms	0.004	0.996	0.000
F39 Unspecified mood [affective] disorder	0.004	0.996	0.000
N76 Other inflammation of vagina and vulva	0.000	0.996	0.004
F33.8 Other recurrent depressive disorders	0.004	0.996	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.004	0.996	0.000
M85.64 Other cyst of bone (Hand)	0.000	0.996	0.003
F33.4 Recurrent depressive disorder, currently in remission	0.004	0.996	0.000
M85.19 Skeletal fluorosis (Site unspecified)	0.000	0.996	0.003
M85.18 Skeletal fluorosis (Other)	0.000	0.996	0.003
M85.17 Skeletal fluorosis (Ankle and foot)	0.000	0.996	0.003
M85.16 Skeletal fluorosis (Lower leg)	0.000	0.996	0.003
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.000	0.996	0.003
M85.14 Skeletal fluorosis (Hand)	0.000	0.996	0.003
M85.13 Skeletal fluorosis (Forearm)	0.000	0.996	0.003
M85.12 Skeletal fluorosis (Upper arm)	0.000	0.996	0.003
M85.11 Skeletal fluorosis (Shoulder region)	0.000	0.996	0.003
M85.10 Skeletal fluorosis (Multiple sites)	0.000	0.996	0.003
M85.29 Hyperostosis of skull-Site unspec	0.000	0.996	0.003
M85.28 Hyperostosis of skull-Other	0.000	0.996	0.003
M85.27 Hyperostosis of skull-Ankle/Foot	0.000	0.996	0.003
M85.26 Hyperostosis of skull-Lower Leg	0.000	0.996	0.003
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.000	0.996	0.003
M85.24 Hyperostosis of skull-Hand	0.000	0.996	0.003
M85.23 Hyperostosis of skull-Forearm	0.000	0.996	0.003
M85.22 Hyperostosis of skull-Upper arm	0.000	0.996	0.003
M85.21 Hyperostosis of skull-Shldr region	0.000	0.996	0.003
M85.20 Hyperostosis of skull-Mult sites	0.000	0.996	0.003
M85.39 Osteitis condensans (Site unspecified)	0.000	0.996	0.003
M85.38 Osteitis condensans (Other)	0.000	0.996	0.003
M85.37 Osteitis condensans (Ankle and foot)	0.000	0.996	0.003
M85.36 Osteitis condensans (Lower leg)	0.000	0.996	0.003
M85.35 Osteitis condensans (Pelvic region and thigh)	0.000	0.996	0.003
M85.34 Osteitis condensans (Hand)	0.000	0.996	0.003
M85.33 Osteitis condensans (Forearm)	0.000	0.996	0.003
M85.32 Osteitis condensans (Upper arm)	0.000	0.996	0.003
M85.31 Osteitis condensans (Shoulder region)	0.000	0.996	0.003
M85.30 Osteitis condensans (Multiple sites)	0.000	0.996	0.003
M85.59 Aneurysmal bone cyst (Site unspecified)	0.000	0.996	0.003
M85.58 Aneurysmal bone cyst (Other)	0.000	0.996	0.003
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.000	0.996	0.003
M85.56 Aneurysmal bone cyst (Lower leg)	0.000	0.996	0.003
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.000	0.996	0.003
M85.54 Aneurysmal bone cyst (Hand)	0.000	0.996	0.003
M85.53 Aneurysmal bone cyst (Forearm)	0.000	0.996	0.003
M85.52 Aneurysmal bone cyst (Upper arm)	0.000	0.996	0.003
M85.51 Aneurysmal bone cyst (Shoulder region)	0.000	0.996	0.003
M85.50 Aneurysmal bone cyst (Multiple sites)	0.000	0.996	0.003
K82.4 Cholesterolosis of gallbladder	0.000	0.996	0.004
S92.50 Fracture of other toe (closed)	0.003	0.996	0.000
S92.5 Fracture of other toe	0.003	0.996	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.000	0.997	0.003
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.000	0.997	0.003
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.000	0.997	0.003
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.000	0.997	0.003
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.000	0.997	0.003
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.000	0.997	0.003
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.000	0.997	0.003
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.000	0.997	0.003
K82.8 Other specified diseases of gallbladder	0.000	0.997	0.003
F30 Manic episode	0.003	0.997	0.000
S92 Fracture of foot, except ankle	0.003	0.997	0.000
M85.49 Solitary bone cyst (Site unspecified)	0.000	0.997	0.003
M85.48 Solitary bone cyst (Other)	0.000	0.997	0.003
M85.46 Solitary bone cyst (Lower leg)	0.000	0.997	0.003
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.000	0.997	0.003
M85.44 Solitary bone cyst (Hand)	0.000	0.997	0.003
M85.43 Solitary bone cyst (Forearm)	0.000	0.997	0.003
M85.42 Solitary bone cyst (Upper arm)	0.000	0.997	0.003
M85.41 Solitary bone cyst (Shoulder region)	0.000	0.997	0.003
M85.40 Solitary bone cyst (Multiple sites)	0.000	0.997	0.003
N76.6 Ulceration of vulva	0.000	0.997	0.003
F38 Other mood [affective] disorders	0.003	0.997	0.000
F34 Persistent mood [affective] disorders	0.003	0.997	0.000
S92.51 Fracture of other toe (open)	0.003	0.997	0.000
S93.0 Dislocation of ankle joint	0.003	0.997	0.000
S92.31 Fracture of metatarsal bone (open)	0.003	0.997	0.000
N76.8 Other specified inflammation of vagina and vulva	0.000	0.997	0.003
M19.04 Primary arthrosis of other joints (Hand)	0.000	0.997	0.003
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.003	0.997	0.000
N76.1 Subacute and chronic vaginitis	0.000	0.997	0.003
T36-T50 Poisoning by drugs, medicaments and biological substances	0.003	0.997	0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.000	0.997	0.003
T43.9 Psychotropic drug, unspecified	0.003	0.997	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.003	0.997	0.000
Q24.5 Malformation of coronary vessels	0.003	0.997	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.997	0.003
F33.0 Recurrent depressive disorder, current episode mild	0.003	0.997	0.000
Q24 Other congenital malformations of heart	0.003	0.997	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.003	0.997	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.003	0.997	0.000
H02 Other disorders of eyelid	0.000	0.997	0.003
M85.47 Solitary bone cyst (Ankle and foot)	0.000	0.997	0.003
M41.99 Scoliosis, unspecified (Site unspecified)	0.003	0.997	0.000
F30.2 Mania with psychotic symptoms	0.003	0.997	0.000
H02.3 Blepharochalasis	0.000	0.997	0.003
Q24.9 Congenital malformation of the heart, unspecified	0.003	0.997	0.000
S92.7 Multiple fractures of foot	0.003	0.997	0.000
O23 Infections of genito-urinary tract in pregnancy	0.000	0.997	0.003
O23.5 Infections of the genital tract in pregnancy	0.000	0.997	0.003
Q27.8 Other specified congenital malformations of peripheral vascular system	0.003	0.997	0.000
F30.1 Mania without psychotic symptoms	0.003	0.997	0.000
S92.1 Fracture of talus	0.003	0.997	0.000
M19.0 Primary arthrosis of other joints	0.000	0.997	0.003
Q27 Other congenital malformations of peripheral vascular system	0.003	0.997	0.000
N76.5 Ulceration of vagina	0.000	0.997	0.003
D25.1 Intramural leiomyoma of uterus	0.000	0.997	0.003
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.003	0.997	0.000
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere	0.000	0.997	0.003
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.000	0.997	0.003
F30.8 Other manic episodes	0.002	0.997	0.000
R47.8 Other and unspecified speech disturbances	0.000	0.997	0.003
S92.9 Fracture of foot, unspecified	0.002	0.997	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.002	0.997	0.000
F34.8 Other persistent mood [affective] disorders	0.002	0.997	0.000
F34.1 Dysthymia	0.002	0.997	0.000
F34.0 Cyclothymia	0.002	0.997	0.000
F38.8 Other specified mood [affective] disorders	0.002	0.997	0.000
F38.1 Other recurrent mood [affective] disorders	0.002	0.997	0.000
F38.0 Other single mood [affective] disorders	0.002	0.997	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.003	0.997	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.003	0.997	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.003	0.997	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
J33.8 Other polyp of sinus	0.003	0.997	0.000
R60.9 Oedema, unspecified	0.003	0.997	0.000
T43.2 Other and unspecified antidepressants	0.003	0.997	0.000
Q24.8 Other specified congenital malformations of heart	0.003	0.997	0.000
R79.8 Other specified abnormal findings of blood chemistry	0.000	0.997	0.003
S93.1 Dislocation of toe(s)	0.003	0.997	0.000
Q23 Congenital malformations of aortic and mitral valves	0.003	0.997	0.000
S92.70 Multiple fractures of foot (closed)	0.002	0.997	0.000
N76.3 Subacute and chronic vulvitis	0.000	0.997	0.002
S93.2 Rupture of ligaments at ankle and foot level	0.002	0.997	0.000
H04.8 Other disorders of lachrymal system	0.000	0.997	0.002
H04 Disorders of lachrymal system	0.000	0.997	0.003
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.002	0.997	0.000
H02.6 Xanthelasma of eyelid	0.000	0.998	0.002
L60.0 Ingrowing nail	0.000	0.998	0.002
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.002	0.998	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.002	0.998	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
F30.0 Hypomania	0.002	0.998	0.000
T40.6 Other and unspecified narcotics	0.002	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.000	0.998	0.002
Q23.1 Congenital insufficiency of aortic valve	0.002	0.998	0.000
S92.0 Fracture of calcaneus	0.002	0.998	0.000
S92.10 Fracture of talus (closed)	0.002	0.998	0.000
Q24.6 Congenital heart block	0.002	0.998	0.000
Q24.4 Congenital subaortic stenosis	0.002	0.998	0.000
Q24.3 Pulmonary infundibular stenosis	0.002	0.998	0.000
Q24.2 Cor triatriatum	0.002	0.998	0.000
Q24.1 Levocardia	0.002	0.998	0.000
S93.4 Sprain and strain of ankle	0.002	0.998	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.002	0.998	0.000
S93.5 Sprain and strain of toe(s)	0.002	0.998	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.000	0.998	0.002
K82 Other diseases of gallbladder	0.000	0.998	0.002
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.998	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.000	0.998	0.002
H02.7 Other degenerative disorders of eyelid and periocular area	0.000	0.998	0.002
J95.8 Other postprocedural respiratory disorders	0.000	0.998	0.002
F30.9 Manic episode, unspecified	0.002	0.998	0.000
N20.0 Calculus of kidney	0.002	0.998	0.000
R44.3 Hallucinations, unspecified	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.002	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.998	0.002
T79.6 Traumatic ischaemia of muscle	0.000	0.998	0.002
S92.71 Multiple fractures of foot (open)	0.002	0.998	0.000
Q23.3 Congenital mitral insufficiency	0.002	0.998	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.000	0.998	0.002
O23.2 Infections of urethra in pregnancy	0.000	0.998	0.002
O23.1 Infections of bladder in pregnancy	0.000	0.998	0.002
S90-S99 Injuries to the ankle and foot	0.002	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.001
S92.11 Fracture of talus (open)	0.002	0.998	0.000
T36 Poisoning by systemic antibiotics	0.002	0.998	0.000
M19.08 Primary arthrosis of other joints (Other)	0.000	0.998	0.002
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.000	0.998	0.002
Q24.0 Dextrocardia	0.002	0.998	0.000
Q27.4 Congenital phlebectasia	0.002	0.998	0.000
Q27.2 Other congenital malformations of renal artery	0.002	0.998	0.000
Q27.1 Congenital renal artery stenosis	0.002	0.998	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.002	0.998	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.002	0.998	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.002	0.998	0.000
H04.1 Other disorders of lachrymal gland	0.000	0.998	0.002
O23.0 Infections of kidney in pregnancy	0.000	0.998	0.002
Q23.0 Congenital stenosis of aortic valve	0.002	0.998	0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.000	0.998	0.002
S92.4 Fracture of great toe	0.002	0.998	0.000
S92.91 Fracture of foot, unspecified (open)	0.002	0.998	0.000
S92.90 Fracture of foot, unspecified (closed)	0.002	0.998	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.002	0.998	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.000	0.998	0.002
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
T44.0 Anticholinesterase agents	0.002	0.998	0.000
T79.8 Other early complications of trauma	0.000	0.998	0.002
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.002	0.998	0.000
Q27.3 Peripheral arteriovenous malformation	0.002	0.998	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.002	0.998	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.002	0.998	0.000
Q23.4 Hypoplastic left heart syndrome	0.002	0.998	0.000
Q23.2 Congenital mitral stenosis	0.002	0.998	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
Q25 Congenital malformations of great arteries	0.002	0.998	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.998	0.002
H04.9 Disorder of lachrymal system, unspecified	0.000	0.998	0.002
T82.1 Mechanical complication of cardiac electronic device	0.002	0.998	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.000	0.998	0.002
H25.9 Senile cataract, unspecified	0.002	0.998	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.002	0.998	0.000
T40.8 Lysergide [LSD]	0.002	0.998	0.000
T40.7 Cannabis (derivatives)	0.002	0.998	0.000
T40.5 Cocaine	0.002	0.998	0.000
T40.3 Methadone	0.002	0.998	0.000
T40.1 Heroin	0.002	0.998	0.000
T40.0 Opium	0.002	0.998	0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.000	0.998	0.002
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
T41.5 Therapeutic gases	0.002	0.998	0.000
T41.4 Anaesthetic, unspecified	0.002	0.998	0.000
T41.3 Local anaesthetics	0.002	0.998	0.000
T41.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
T41.1 Intravenous anaesthetics	0.002	0.998	0.000
T41.0 Inhaled anaesthetics	0.002	0.998	0.000
T49.9 Topical agent, unspecified	0.002	0.998	0.000
T49.8 Other topical agents	0.002	0.998	0.000
T49.7 Dental drugs, topically applied	0.002	0.998	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
T49.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
T49.3 Emollients, demulcents and protectants	0.002	0.998	0.000
T49.2 Local astringents and local detergents	0.002	0.998	0.000
T49.1 Antipruritics	0.002	0.998	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
Q26 Congenital malformations of great veins	0.002	0.998	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.002	0.998	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.002	0.998	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
T48.5 Anti-common-cold drugs	0.002	0.998	0.000
T48.4 Expectorants	0.002	0.998	0.000
T48.3 Antitussives	0.002	0.998	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
T48.0 Oxytocic drugs	0.002	0.998	0.000
T79.9 Unspecified early complication of trauma	0.000	0.998	0.002
T79.2 Traumatic secondary and recurrent haemorrhage	0.000	0.998	0.002
T79.1 Fat embolism (traumatic)	0.000	0.998	0.002
T79.0 Air embolism (traumatic)	0.000	0.998	0.002
M80-M85 Disorders of bone density and structure	0.000	0.998	0.002
S92.01 Fracture of calcaneus (open)	0.002	0.998	0.000
S93.40 Sprain of unspecified ligament of ankle	0.002	0.998	0.000
H02.2 Lagophthalmos	0.000	0.998	0.002
K35.8 Acute appendicitis, other and unspecified	0.000	0.998	0.002
K82.9 Disease of gallbladder, unspecified	0.000	0.998	0.002
Q25.4 Other congenital malformations of aorta	0.002	0.998	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
T47.7 Emetics	0.002	0.998	0.000
T47.6 Antidiarrhoeal drugs	0.002	0.998	0.000
T47.5 Digestants	0.002	0.998	0.000
T47.4 Other laxatives	0.002	0.998	0.000
T47.3 Saline and osmotic laxatives	0.002	0.998	0.000
T47.2 Stimulant laxatives	0.002	0.998	0.000
T47.0 Histamine H(2)-receptor antagonists	0.002	0.998	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
S97 Crushing injury of ankle and foot	0.002	0.998	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.000	0.998	0.002
S90.0 Contusion of ankle	0.002	0.998	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
T37.5 Antiviral drugs	0.002	0.998	0.000
T37.4 Anthelminthics	0.002	0.998	0.000
T37.3 Other antiprotozoal drugs	0.002	0.998	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
T37.1 Antimycobacterial drugs	0.002	0.998	0.000
T37.0 Sulphonamides	0.002	0.998	0.000
T40.2 Other opioids	0.002	0.998	0.000
T42.4 Benzodiazepines	0.002	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
T46.7 Peripheral vasodilators	0.002	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.002	0.998	0.000
S90.3 Contusion of other and unspecified parts of foot	0.002	0.998	0.000
T79.5 Traumatic anuria	0.000	0.998	0.002
K82.0 Obstruction of gallbladder	0.000	0.998	0.002
Q25.6 Stenosis of pulmonary artery	0.002	0.998	0.000
M70.46 Prepatellar bursitis-Lower Leg	0.000	0.998	0.002
T36.3 Macrolides	0.002	0.998	0.000
S98 Traumatic amputation of ankle and foot	0.002	0.998	0.000
S95 Injury of blood vessels at ankle and foot level	0.002	0.998	0.000
S94 Injury of nerves at ankle and foot level	0.002	0.998	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.001	0.998	0.001
E66.8 Other obesity	0.000	0.998	0.002
T50.8 Diagnostic agents	0.002	0.998	0.000
T36.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
T36.8 Other systemic antibiotics	0.002	0.998	0.000
T36.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
T36.6 Rifamycins	0.002	0.998	0.000
T36.5 Aminoglycosides	0.002	0.998	0.000
T36.4 Tetracyclines	0.002	0.998	0.000
T36.2 Chloramphenicol group	0.002	0.998	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.002	0.998	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.000	0.998	0.002
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.000	0.998	0.002
R79.0 Abnormal level of blood mineral	0.000	0.998	0.002
D25.2 Subserosal leiomyoma of uterus	0.000	0.998	0.002
H04.6 Other changes in lachrymal passages	0.000	0.998	0.002
Q25.7 Other congenital malformations of pulmonary artery	0.002	0.998	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
M82 Osteoporosis in diseases classified elsewhere	0.000	0.998	0.002
M70.22 Olecranon bursitis-Upper arm	0.000	0.998	0.002
H04.0 Dacryoadenitis	0.000	0.998	0.002
O12.0 Gestational oedema	0.002	0.998	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.000	0.998	0.002
H02.4 Ptosis of eyelid	0.000	0.998	0.002
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.002	0.998	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.002	0.998	0.000
T42.3 Barbiturates	0.002	0.998	0.000
T42.2 Succinimides and oxazolidinediones	0.002	0.998	0.000
K82.3 Fistula of gallbladder	0.000	0.998	0.002
S96.8 Injury of other muscles and tendons at ankle and foot level	0.002	0.998	0.000
S97.1 Crushing injury of toe(s)	0.002	0.998	0.000
T50.7 Analeptics and opioid receptor antagonists	0.002	0.998	0.000
T50.5 Appetite depressants	0.002	0.998	0.000
T50.4 Drugs affecting uric acid metabolism	0.002	0.998	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.002	0.998	0.000
T50.1 Loop [high-ceiling] diuretics	0.002	0.998	0.000
T50.0 Mineralocorticoids and their antagonists	0.002	0.998	0.000
R79 Other abnormal findings of blood chemistry	0.000	0.998	0.002
M47.87 Other spondylosis (Lumbosacral region)	0.002	0.998	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.001	0.998	0.001
Q25.9 Congenital malformation of great arteries, unspecified	0.002	0.998	0.000
Q25.8 Other congenital malformations of great arteries	0.002	0.998	0.000
Q25.5 Atresia of pulmonary artery	0.002	0.998	0.000
Q25.3 Stenosis of aorta	0.002	0.998	0.000
Q25.2 Atresia of aorta	0.002	0.998	0.000
T79.4 Traumatic shock	0.000	0.998	0.002
H02.5 Other disorders affecting eyelid function	0.000	0.998	0.002
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere	0.000	0.998	0.002
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.002	0.998	0.000
F60 Specific personality disorders	0.002	0.998	0.000
K82.2 Perforation of gallbladder	0.000	0.998	0.002
N34.2 Other urethritis	0.000	0.998	0.002
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.000	0.998	0.002
T46.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
T46.1 Calcium-channel blockers	0.002	0.998	0.000
R47-R49 Symptoms and signs involving speech and voice	0.000	0.998	0.002
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.998	0.002
F60.2 Dissocial personality disorder	0.002	0.998	0.000
G45.3 Amaurosis fugax	0.000	0.998	0.002
L50.0 Allergic urticaria	0.002	0.998	0.000
M82.1 Osteoporosis in endocrine disorders	0.000	0.998	0.002
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.002	0.998	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.002	0.998	0.000
Q20.6 Isomerism of atrial appendages	0.002	0.998	0.000
Q20.5 Discordant atrioventricular connexion	0.002	0.998	0.000
Q20.4 Double inlet ventricle	0.002	0.998	0.000
Q20.3 Discordant ventriculoarterial connexion	0.002	0.998	0.000
Q20.2 Double outlet left ventricle	0.002	0.998	0.000
Q20.1 Double outlet right ventricle	0.002	0.998	0.000
Q20.0 Common arterial trunk	0.002	0.998	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.002	0.998	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.002	0.998	0.000
Q22.6 Hypoplastic right heart syndrome	0.002	0.998	0.000
Q22.5 Ebstein's anomaly	0.002	0.998	0.000
Q22.4 Congenital tricuspid stenosis	0.002	0.998	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.002	0.998	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.002	0.998	0.000
Q22.1 Congenital pulmonary valve stenosis	0.002	0.998	0.000
Q22.0 Pulmonary valve atresia	0.002	0.998	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.002	0.998	0.000
Q26.8 Other congenital malformations of great veins	0.002	0.998	0.000
Q26.6 Portal vein-hepatic artery fistula	0.002	0.998	0.000
Q26.5 Anomalous portal venous connexion	0.002	0.998	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.002	0.998	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.002	0.998	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.002	0.998	0.000
Q26.1 Persistent left superior vena cava	0.002	0.998	0.000
Q26.0 Congenital stenosis of vena cava	0.002	0.998	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.002	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.002	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.002	0.998	0.000
L60.3 Nail dystrophy	0.000	0.998	0.002
R44.1 Visual hallucinations	0.002	0.998	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.002	0.998	0.000
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
S92.41 Fracture of great toe (open)	0.001	0.998	0.000
M70.4 Prepatellar bursitis	0.000	0.998	0.002
S51.9 Open wound of forearm, part unspecified	0.000	0.998	0.002
S97.0 Crushing injury of ankle	0.002	0.998	0.000
Z93.0 Tracheostomy status	0.000	0.998	0.002
R93 Abnormal findings on diagnostic imaging of other body structures	0.000	0.998	0.002
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations