TreeWAS – Variant ID: rs362536

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.015	0.985
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.017	0.983
E03 Other hypothyroidism	0.000	0.018	0.982
E00-E07 Disorders of thyroid gland	0.000	0.026	0.974
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.035	0.965
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.172	0.828
N40 Hyperplasia of prostate	0.785	0.215	0.000
N42 Other disorders of prostate	0.761	0.239	0.000
N42.8 Other specified disorders of prostate	0.759	0.241	0.000
N42.2 Atrophy of prostate	0.726	0.274	0.000
N42.1 Congestion and haemorrhage of prostate	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.000	0.295	0.704
E05.4 Thyrotoxicosis factitia	0.000	0.295	0.704
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.295	0.704
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.295	0.704
E03.5 Myxoedema coma	0.000	0.296	0.704
E03.4 Atrophy of thyroid (acquired)	0.000	0.296	0.704
E03.3 Postinfectious hypothyroidism	0.000	0.296	0.704
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.301	0.698
E00 Congenital iodine-deficiency syndrome	0.000	0.301	0.698
N42.9 Disorder of prostate, unspecified	0.698	0.302	0.000
N40-N51 Diseases of male genital organs	0.685	0.315	0.000
E06 Thyroiditis	0.000	0.345	0.655
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.370	0.630
E03.8 Other specified hypothyroidism	0.000	0.428	0.572
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.444	0.556
N44 Torsion of testis	0.553	0.447	0.000
E03.1 Congenital hypothyroidism without goitre	0.000	0.458	0.542
E06.5 Other chronic thyroiditis	0.000	0.471	0.529
N42.3 Dysplasia of prostate	0.518	0.482	0.000
N43 Hydrocele and spermatocele	0.515	0.485	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.499	0.501
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.499	0.501
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.499	0.501
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.499	0.501
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.499	0.501
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.499	0.501
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.499	0.501
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.499	0.501
E07 Other disorders of thyroid	0.000	0.510	0.490
N51 Disorders of male genital organs in diseases classified elsewhere	0.485	0.515	0.000
E06.4 Drug-induced thyroiditis	0.000	0.530	0.470
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.530	0.470
E06.0 Acute thyroiditis	0.000	0.530	0.470
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.543	0.456
E06.1 Subacute thyroiditis	0.000	0.559	0.441
E05.8 Other thyrotoxicosis	0.001	0.565	0.434
E06.3 Autoimmune thyroiditis	0.000	0.570	0.430
E06.9 Thyroiditis, unspecified	0.000	0.583	0.417
E83 Disorders of mineral metabolism	0.000	0.596	0.404
K90 Intestinal malabsorption	0.000	0.606	0.394
N43.2 Other hydrocele	0.389	0.611	0.000
N43.4 Spermatocele	0.381	0.619	0.000
N43.1 Infected hydrocele	0.378	0.622	0.000
N43.0 Encysted hydrocele	0.369	0.631	0.000
E83.5 Disorders of calcium metabolism	0.000	0.632	0.368
N46 Male infertility	0.363	0.637	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.363	0.637	0.000
N41 Inflammatory diseases of prostate	0.353	0.647	0.000
E07.1 Dyshormogenetic goitre	0.000	0.648	0.351
E07.0 Hypersecretion of calcitonin	0.000	0.648	0.351
N43.3 Hydrocele, unspecified	0.350	0.650	0.000
N51.8 Other disorders of male genital organs in diseases classified elsewhere	0.348	0.652	0.000
N51.1 Disorders of testis and epididymis in diseases classified elsewhere	0.348	0.652	0.000
N51.0 Disorders of prostate in diseases classified elsewhere	0.348	0.652	0.000
N50 Other disorders of male genital organs	0.344	0.656	0.000
N51.2 Balanitis in diseases classified elsewhere	0.342	0.658	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.698	0.302
N50.9 Disorder of male genital organs, unspecified	0.300	0.700	0.000
K90.8 Other intestinal malabsorption	0.000	0.709	0.291
E07.8 Other specified disorders of thyroid	0.000	0.710	0.289
E83.8 Other disorders of mineral metabolism	0.000	0.710	0.289
E83.2 Disorders of zinc metabolism	0.000	0.710	0.289
E83.0 Disorders of copper metabolism	0.000	0.710	0.289
K90.3 Pancreatic steatorrhoea	0.000	0.717	0.282
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.717	0.282
K90.1 Tropical sprue	0.000	0.717	0.282
N41.2 Abscess of prostate	0.279	0.721	0.000
N42.0 Calculus of prostate	0.264	0.736	0.001
N45 Orchitis and epididymitis	0.261	0.739	0.000
N49.9 Inflammatory disorder of unspecified male genital organ	0.260	0.740	0.000
N49.0 Inflammatory disorders of seminal vesicle	0.260	0.740	0.000
N41.8 Other inflammatory diseases of prostate	0.257	0.743	0.000
N41.3 Prostatocystitis	0.253	0.747	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.750	0.250
N41.0 Acute prostatitis	0.249	0.751	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.753	0.247
N49.8 Inflammatory disorders of other specified male genital organs	0.240	0.760	0.000
E83.3 Disorders of phosphorus metabolism	0.000	0.764	0.236
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens	0.233	0.767	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.780	0.220
N50.1 Vascular disorders of male genital organs	0.219	0.781	0.000
N49.2 Inflammatory disorders of scrotum	0.209	0.791	0.000
N41.1 Chronic prostatitis	0.205	0.795	0.000
E83.4 Disorders of magnesium metabolism	0.000	0.800	0.200
G35 Multiple sclerosis	0.000	0.825	0.175
N50.0 Atrophy of testis	0.159	0.840	0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess	0.138	0.862	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.137	0.863	0.000
N50.8 Other specified disorders of male genital organs	0.121	0.879	0.000
E04 Other non-toxic goitre	0.000	0.910	0.090
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.078	0.922	0.000
E04.0 Non-toxic diffuse goitre	0.000	0.932	0.068
E04.8 Other specified non-toxic goitre	0.000	0.935	0.064
N47 Redundant prepuce, phimosis and paraphimosis	0.056	0.944	0.000
M20.1 Hallux valgus (acquired)	0.049	0.951	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.958	0.042
C44.3 Skin of other and unspecified parts of face	0.000	0.965	0.035
J38.4 Oedema of larynx	0.000	0.968	0.032
K72.9 Hepatic failure, unspecified	0.000	0.969	0.031
G36 Other acute disseminated demyelination	0.000	0.969	0.031
K90-K93 Other diseases of the digestive system	0.000	0.970	0.030
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.971	0.029
S62.20 Fracture of first metacarpal bone (closed)	0.029	0.971	0.000
E70-E90 Metabolic disorders	0.000	0.971	0.029
K11.5 Sialolithiasis	0.028	0.972	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.000	0.972	0.028
J38.3 Other diseases of vocal cords	0.000	0.973	0.027
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.973	0.027
M35.0 Sicca syndrome [Sjogren]	0.000	0.974	0.026
E89.0 Postprocedural hypothyroidism	0.000	0.975	0.025
J38.7 Other diseases of larynx	0.000	0.975	0.025
N28.9 Disorder of kidney and ureter, unspecified	0.000	0.975	0.025
J38.2 Nodules of vocal cords	0.000	0.977	0.023
G36.0 Neuromyelitis optica [Devic]	0.000	0.977	0.023
G36.9 Acute disseminated demyelination, unspecified	0.000	0.978	0.022
G36.8 Other specified acute disseminated demyelination	0.000	0.978	0.022
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.978	0.022
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.978	0.022
E89.3 Postprocedural hypopituitarism	0.000	0.978	0.022
J38.1 Polyp of vocal cord and larynx	0.000	0.979	0.021
E89.2 Postprocedural hypoparathyroidism	0.000	0.979	0.021
N48 Other disorders of penis	0.021	0.979	0.000
E84 Cystic fibrosis	0.000	0.979	0.021
E76 Disorders of glycosaminoglycan metabolism	0.000	0.979	0.021
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.979	0.021
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.979	0.021
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.980	0.020
K72 Hepatic failure, not elsewhere classified	0.000	0.980	0.020
J38.5 Laryngeal spasm	0.000	0.980	0.020
E89.1 Postprocedural hypoinsulinaemia	0.000	0.980	0.020
J38.6 Stenosis of larynx	0.000	0.980	0.020
E70 Disorders of aromatic amino-acid metabolism	0.000	0.980	0.020
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.981	0.019
E89.5 Postprocedural testicular hypofunction	0.000	0.981	0.019
E40-E46 Malnutrition	0.000	0.981	0.019
E77 Disorders of glycoprotein metabolism	0.000	0.981	0.019
E74 Other disorders of carbohydrate metabolism	0.000	0.982	0.018
E72 Other disorders of amino-acid metabolism	0.000	0.982	0.018
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.982	0.018
K11 Diseases of salivary glands	0.018	0.982	0.000
E79 Disorders of purine and pyrimidine metabolism	0.000	0.982	0.017
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.982	0.017
K11.2 Sialoadenitis	0.018	0.982	0.000
E89.4 Postprocedural ovarian failure	0.000	0.983	0.017
S62.2 Fracture of first metacarpal bone	0.017	0.983	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.983	0.017
N48.5 Ulcer of penis	0.017	0.983	0.000
I84.6 Residual haemorrhoidal skin tags	0.000	0.983	0.017
K72.0 Acute and subacute hepatic failure	0.000	0.984	0.016
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.984	0.016
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.984	0.016
K93.1 Megacolon in Chagas' disease	0.000	0.984	0.016
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.984	0.016
K11.7 Disturbances of salivary secretion	0.015	0.985	0.000
E84.9 Cystic fibrosis, unspecified	0.000	0.985	0.015
E84.8 Cystic fibrosis with other manifestations	0.000	0.985	0.015
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.985	0.015
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.985	0.015
E71.3 Disorders of fatty-acid metabolism	0.000	0.985	0.015
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.985	0.015
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.985	0.015
E71.0 Maple-syrup-urine disease	0.000	0.985	0.015
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.985	0.015
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.985	0.015
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.985	0.015
E76.2 Other mucopolysaccharidoses	0.000	0.985	0.015
E76.1 Mucopolysaccharidosis, type II	0.000	0.985	0.015
E76.0 Mucopolysaccharidosis, type I	0.000	0.985	0.015
E73 Lactose intolerance	0.000	0.985	0.015
G37 Other demyelinating diseases of central nervous system	0.001	0.985	0.014
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.985	0.015
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.985	0.015
J38.0 Paralysis of vocal cords and larynx	0.000	0.985	0.015
N48.3 Priapism	0.014	0.985	0.000
K72.1 Chronic hepatic failure	0.000	0.986	0.014
E04.2 Non-toxic multinodular goitre	0.000	0.986	0.014
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.986	0.014
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.986	0.014
E70.2 Disorders of tyrosine metabolism	0.000	0.986	0.014
E70.1 Other hyperphenylalaninaemias	0.000	0.986	0.014
E70.0 Classical phenylketonuria	0.000	0.986	0.014
E80.1 Porphyria cutanea tarda	0.000	0.986	0.014
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.986	0.014
E45 Retarded development following protein-energy malnutrition	0.000	0.986	0.014
E43 Unspecified severe protein-energy malnutrition	0.000	0.986	0.014
E42 Marasmic kwashiorkor	0.000	0.986	0.014
E41 Nutritional marasmus	0.000	0.986	0.014
E40 Kwashiorkor	0.000	0.986	0.014
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.986	0.014
E77.1 Defects in glycoprotein degradation	0.000	0.986	0.014
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.986	0.014
M45.X9 Ankylosing spondylitis (Site unspecified)	0.014	0.986	0.000
E70.3 Albinism	0.000	0.987	0.013
E78.8 Other disorders of lipoprotein metabolism	0.000	0.987	0.013
E04.1 Non-toxic single thyroid nodule	0.000	0.987	0.013
E80.2 Other porphyria	0.000	0.987	0.013
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.987	0.013
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.987	0.013
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.987	0.013
E74.2 Disorders of galactose metabolism	0.000	0.987	0.013
E74.1 Disorders of fructose metabolism	0.000	0.987	0.013
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.987	0.013
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.987	0.013
E72.5 Disorders of glycine metabolism	0.000	0.987	0.013
E72.4 Disorders of ornithine metabolism	0.000	0.987	0.013
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.987	0.013
E72.2 Disorders of urea cycle metabolism	0.000	0.987	0.013
E75.6 Lipid storage disorder, unspecified	0.000	0.987	0.013
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.987	0.013
E75.3 Sphingolipidosis, unspecified	0.000	0.987	0.013
E75.1 Other gangliosidosis	0.000	0.987	0.013
E75.0 GM2 gangliosidosis	0.000	0.987	0.013
K11.9 Disease of salivary gland, unspecified	0.013	0.987	0.000
E74.0 Glycogen storage disease	0.000	0.987	0.013
K11.4 Fistula of salivary gland	0.013	0.987	0.000
K11.0 Atrophy of salivary gland	0.013	0.987	0.000
K11.3 Abscess of salivary gland	0.013	0.987	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.987	0.013
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.987	0.013
E79.1 Lesch-Nyhan syndrome	0.000	0.987	0.013
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.987	0.013
E80.5 Crigler-Najjar syndrome	0.000	0.987	0.013
E80.3 Defects of catalase and peroxydase	0.000	0.987	0.013
E80.0 Hereditary erythropoietic porphyria	0.000	0.987	0.013
N48.1 Balanoposthitis	0.013	0.987	0.000
E88 Other metabolic disorders	0.000	0.987	0.012
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.988	0.012
S62.21 Fracture of first metacarpal bone (open)	0.012	0.988	0.000
E15 Nondiabetic hypoglycaemic coma	0.000	0.988	0.012
N48.6 Balanitis xerotica obliterans	0.012	0.988	0.000
E75.2 Other sphingolipidosis	0.000	0.988	0.012
E77.8 Other disorders of glycoprotein metabolism	0.000	0.988	0.012
E46 Unspecified protein-energy malnutrition	0.000	0.988	0.012
K11.1 Hypertrophy of salivary gland	0.012	0.988	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.988	0.011
E78.4 Other hyperlipidaemia	0.000	0.988	0.012
E72.0 Disorders of amino-acid transport	0.000	0.989	0.011
M20.3 Other deformity of hallux (acquired)	0.011	0.989	0.000
K11.6 Mucocele of salivary gland	0.011	0.989	0.000
E78.6 Lipoprotein deficiency	0.000	0.989	0.011
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.989	0.011
E75.5 Other lipid storage disorders	0.000	0.989	0.011
H34.8 Other retinal vascular occlusions	0.000	0.989	0.011
E73.8 Other lactose intolerance	0.000	0.989	0.011
E73.1 Secondary lactase deficiency	0.000	0.989	0.011
E73.0 Congenital lactase deficiency	0.000	0.989	0.011
G37.5 Concentric sclerosis [Balo]	0.001	0.989	0.010
G37.4 Subacute necrotising myelitis	0.001	0.989	0.010
G37.2 Central pontine myelinolysis	0.001	0.989	0.010
G37.1 Central demyelination of corpus callosum	0.001	0.989	0.010
G37.0 Diffuse sclerosis	0.001	0.989	0.010
S62.30 Fracture of other metacarpal bone (closed)	0.011	0.989	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.000	0.989	0.011
E80.6 Other disorders of bilirubin metabolism	0.000	0.989	0.010
R01.1 Cardiac murmur, unspecified	0.011	0.989	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.011	0.989	0.000
N48.9 Disorder of penis, unspecified	0.010	0.989	0.000
E44.1 Mild protein-energy malnutrition	0.000	0.990	0.010
E44.0 Moderate protein-energy malnutrition	0.000	0.990	0.010
E78.3 Hyperchylomicronaemia	0.000	0.990	0.010
E88.8 Other specified metabolic disorders	0.000	0.990	0.010
E65-E68 Obesity and other hyperalimentation	0.000	0.990	0.010
E78.1 Pure hyperglyceridaemia	0.000	0.990	0.010
N48.0 Leukoplakia of penis	0.010	0.990	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.990	0.009
K70-K77 Diseases of liver	0.000	0.990	0.010
S62.3 Fracture of other metacarpal bone	0.010	0.990	0.000
N48.2 Other inflammatory disorders of penis	0.009	0.991	0.000
M20 Acquired deformities of fingers and toes	0.009	0.991	0.000
Z99.1 Dependence on respirator	0.009	0.991	0.000
E88.9 Metabolic disorder, unspecified	0.000	0.991	0.009
N28.8 Other specified disorders of kidney and ureter	0.000	0.991	0.009
K74 Fibrosis and cirrhosis of liver	0.000	0.991	0.009
K75 Other inflammatory liver diseases	0.000	0.991	0.009
E80.4 Gilbert's syndrome	0.000	0.991	0.009
M94.88 Other specified disorders of cartilage (Other)	0.009	0.991	0.000
S62 Fracture at wrist and hand level	0.008	0.992	0.000
E88.3 Tumour lysis syndrome	0.000	0.992	0.008
K75.4 Autoimmune hepatitis	0.000	0.992	0.008
K74.0 Hepatic fibrosis	0.000	0.992	0.008
E16 Other disorders of pancreatic internal secretion	0.000	0.992	0.008
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.992	0.008
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.008	0.992	0.000
M35 Other systemic involvement of connective tissue	0.000	0.992	0.008
S62.31 Fracture of other metacarpal bone (open)	0.008	0.992	0.000
E50-E64 Other nutritional deficiencies	0.000	0.992	0.008
E67 Other hyperalimentation	0.000	0.992	0.007
E68 Sequelae of hyperalimentation	0.000	0.992	0.007
K71 Toxic liver disease	0.000	0.993	0.007
M20.6 Acquired deformity of toe(s), unspecified	0.007	0.993	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.993	0.007
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.993	0.007
K73 Chronic hepatitis, not elsewhere classified	0.000	0.993	0.007
E88.2 Lipomatosis, not elsewhere classified	0.000	0.993	0.007
N28.0 Ischaemia and infarction of kidney	0.000	0.993	0.007
K77 Liver disorders in diseases classified elsewhere	0.000	0.993	0.007
M62.8 Other specified disorders of muscle	0.007	0.993	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.993	0.007
L40.9 Psoriasis, unspecified	0.007	0.993	0.000
E85 Amyloidosis	0.002	0.993	0.006
K75.8 Other specified inflammatory liver diseases	0.000	0.993	0.007
M62.88 Other specified disorders of muscle (Other)	0.007	0.993	0.000
K74.3 Primary biliary cirrhosis	0.000	0.993	0.007
M45 Ankylosing spondylitis	0.007	0.993	0.000
M35.1 Other overlap syndromes	0.000	0.993	0.007
E86 Volume depletion	0.000	0.993	0.007
K74.5 Biliary cirrhosis, unspecified	0.000	0.993	0.007
R50.0 Fever with chills	0.007	0.993	0.000
K74.4 Secondary biliary cirrhosis	0.000	0.993	0.007
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.993	0.007
K74.1 Hepatic sclerosis	0.000	0.993	0.007
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.007	0.993	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.007	0.993	0.000
E04.9 Non-toxic goitre, unspecified	0.001	0.993	0.006
K75.2 Nonspecific reactive hepatitis	0.000	0.993	0.006
K75.1 Phlebitis of portal vein	0.000	0.993	0.006
K75.9 Inflammatory liver disease, unspecified	0.000	0.993	0.007
K74.6 Other and unspecified cirrhosis of liver	0.000	0.994	0.006
L60.8 Other nail disorders	0.006	0.994	0.000
K71.0 Toxic liver disease with cholestasis	0.000	0.994	0.006
K73.9 Chronic hepatitis, unspecified	0.000	0.994	0.006
N25-N29 Other disorders of kidney and ureter	0.000	0.994	0.006
E65 Localised adiposity	0.000	0.994	0.006
S62.7 Multiple fractures of fingers	0.006	0.994	0.000
H34 Retinal vascular occlusions	0.000	0.994	0.006
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.994	0.006
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.994	0.006
E16.4 Abnormal secretion of gastrin	0.000	0.994	0.006
E16.3 Increased secretion of glucagon	0.000	0.994	0.006
L72.8 Other follicular cysts of skin and subcutaneous tissue	0.006	0.994	0.000
S62.4 Multiple fractures of metacarpal bones	0.006	0.994	0.000
E58 Dietary calcium deficiency	0.000	0.994	0.006
K91.1 Postgastric surgery syndromes	0.000	0.994	0.006
M62 Other disorders of muscle	0.006	0.994	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.994	0.006
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.994	0.006
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.994	0.006
S62.1 Fracture of other carpal bone(s)	0.006	0.994	0.000
L72 Follicular cysts of skin and subcutaneous tissue	0.006	0.994	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.006	0.994	0.000
N48.8 Other specified disorders of penis	0.006	0.994	0.000
K75.0 Abscess of liver	0.000	0.994	0.006
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.994	0.006
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.994	0.006
M35.5 Multifocal fibrosclerosis	0.000	0.994	0.006
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.994	0.006
M62.89 Other specified disorders of muscle (Site unspecified)	0.006	0.994	0.000
K11.8 Other diseases of salivary glands	0.005	0.994	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.994	0.006
E63 Other nutritional deficiencies	0.000	0.994	0.006
E50 Vitamin A deficiency	0.000	0.994	0.006
E60 Dietary zinc deficiency	0.000	0.994	0.006
E59 Dietary selenium deficiency	0.000	0.994	0.006
E52 Niacin deficiency [pellagra]	0.000	0.994	0.006
E78.2 Mixed hyperlipidaemia	0.000	0.994	0.006
E67.8 Other specified hyperalimentation	0.000	0.994	0.005
E67.3 Hypervitaminosis D	0.000	0.994	0.005
E67.2 Megavitamin-B6 syndrome	0.000	0.994	0.005
E67.1 Hypercarotenaemia	0.000	0.994	0.005
E67.0 Hypervitaminosis A	0.000	0.994	0.005
M35.2 Behcet's disease	0.000	0.994	0.006
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.994	0.006
M21.3 Wrist or foot drop (acquired)	0.006	0.994	0.000
K76.6 Portal hypertension	0.000	0.994	0.006
M62.83 Other specified disorders of muscle (Forearm)	0.006	0.994	0.000
S62.5 Fracture of thumb	0.006	0.994	0.000
N26 Unspecified contracted kidney	0.000	0.994	0.006
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.994	0.005
M35.8 Other specified systemic involvement of connective tissue	0.000	0.994	0.005
L60 Nail disorders	0.006	0.994	0.000
K71.9 Toxic liver disease, unspecified	0.000	0.994	0.005
K71.8 Toxic liver disease with other disorders of liver	0.000	0.994	0.005
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.994	0.005
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.994	0.005
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.994	0.005
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.994	0.005
K71.2 Toxic liver disease with acute hepatitis	0.000	0.994	0.005
S62.8 Fracture of other and unspecified parts of wrist and hand	0.006	0.994	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.006	0.994	0.000
R01 Cardiac murmurs and other cardiac sounds	0.006	0.994	0.000
N60.1 Diffuse cystic mastopathy	0.000	0.994	0.006
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.994	0.005
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.994	0.005
E51 Thiamine deficiency	0.000	0.994	0.005
K91.5 Postcholecystectomy syndrome	0.000	0.994	0.005
E73.9 Lactose intolerance, unspecified	0.001	0.995	0.005
H34.2 Other retinal artery occlusions	0.000	0.995	0.005
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.995	0.005
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.995	0.005
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.001	0.995	0.004
M62.87 Other specified disorders of muscle (Ankle and foot)	0.005	0.995	0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.005	0.995	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.005	0.995	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.001	0.995	0.004
E85.1 Neuropathic heredofamilial amyloidosis	0.001	0.995	0.004
E85.0 Nonneuropathic heredofamilial amyloidosis	0.001	0.995	0.004
E56 Other vitamin deficiencies	0.000	0.995	0.005
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.005	0.995	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.005	0.995	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.005	0.995	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.005	0.995	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.005	0.995	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.005	0.995	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.005	0.995	0.000
M62.6 Muscle strain	0.005	0.995	0.000
L60.2 Onychogryphosis	0.005	0.995	0.000
M62.4 Contracture of muscle	0.005	0.995	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.005	0.995	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.995	0.005
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.995	0.005
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.000	0.995	0.005
M62.81 Other specified disorders of muscle (Shoulder region)	0.005	0.995	0.000
E61 Deficiency of other nutrient elements	0.000	0.995	0.005
K43.0 Ventral hernia with obstruction, without gangrene	0.000	0.995	0.005
S62.70 Multiple fractures of fingers (closed)	0.005	0.995	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.005	0.995	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.005	0.995	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.001	0.995	0.004
N81.3 Complete uterovaginal prolapse	0.005	0.995	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.005	0.995	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.005	0.995	0.000
E85.8 Other amyloidosis	0.001	0.995	0.003
M94.8 Other specified disorders of cartilage	0.005	0.995	0.000
R01.0 Benign and innocent cardiac murmurs	0.005	0.995	0.000
D33.3 Cranial nerves	0.000	0.995	0.005
M62.84 Other specified disorders of muscle (Hand)	0.005	0.995	0.000
M62.0 Diastasis of muscle	0.005	0.995	0.000
L60-L75 Disorders of skin appendages	0.005	0.995	0.000
H34.1 Central retinal artery occlusion	0.000	0.995	0.005
L60.0 Ingrowing nail	0.005	0.995	0.000
L71 Rosacea	0.005	0.995	0.000
H34.0 Transient retinal artery occlusion	0.000	0.995	0.005
M35.7 Hypermobility syndrome	0.000	0.995	0.005
L72.2 Steatocystoma multiplex	0.005	0.995	0.000
S62.41 Multiple fractures of metacarpal bones (open)	0.004	0.995	0.000
N27 Small kidney of unknown cause	0.000	0.995	0.005
K43.9 Ventral hernia without obstruction or gangrene	0.000	0.995	0.005
M62.3 Immobility syndrome (paraplegic)	0.004	0.995	0.000
E54 Ascorbic acid deficiency	0.000	0.995	0.004
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.005	0.995	0.000
S62.11 Fracture of other carpal bone(s) (open)	0.004	0.995	0.000
M62.2 Ischaemic infarction of muscle	0.004	0.995	0.000
M89.0 Algoneurodystrophy	0.005	0.995	0.000
M20.5 Other deformities of toe(s) (acquired)	0.005	0.995	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.004	0.995	0.000
M62.46 Contracture of muscle (Lower leg)	0.004	0.995	0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.000	0.996	0.004
H34.9 Retinal vascular occlusion, unspecified	0.000	0.996	0.004
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.004	0.996	0.000
E50.9 Vitamin A deficiency, unspecified	0.000	0.996	0.004
E50.8 Other manifestations of vitamin A deficiency	0.000	0.996	0.004
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.996	0.004
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.996	0.004
E50.5 Vitamin A deficiency with night blindness	0.000	0.996	0.004
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.996	0.004
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.996	0.004
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.996	0.004
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.996	0.004
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.996	0.004
E63.9 Nutritional deficiency, unspecified	0.000	0.996	0.004
E63.8 Other specified nutritional deficiencies	0.000	0.996	0.004
E63.1 Imbalance of constituents of food intake	0.000	0.996	0.004
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.996	0.004
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.996	0.004
E64.8 Sequelae of other nutritional deficiencies	0.000	0.996	0.004
E64.3 Sequelae of rickets	0.000	0.996	0.004
E64.2 Sequelae of vitamin C deficiency	0.000	0.996	0.004
E64.1 Sequelae of vitamin A deficiency	0.000	0.996	0.004
E64.0 Sequelae of protein-energy malnutrition	0.000	0.996	0.004
E85.3 Secondary systemic amyloidosis	0.002	0.996	0.003
M45.X2 Ankylosing spondylitis (Cervical region)	0.004	0.996	0.000
M62.9 Disorder of muscle, unspecified	0.004	0.996	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.004	0.996	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.004	0.996	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.004	0.996	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.004	0.996	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.004	0.996	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.004	0.996	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.004	0.996	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.004	0.996	0.000
S62.40 Multiple fractures of metacarpal bones (closed)	0.004	0.996	0.000
L60.1 Onycholysis	0.004	0.996	0.000
E53 Deficiency of other B group vitamins	0.000	0.996	0.004
N25 Disorders resulting from impaired renal tubular function	0.000	0.996	0.004
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.004	0.996	0.000
M89.9 Disorder of bone, unspecified	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations