TreeWAS – Variant ID: rs365060

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.5 Disorders of calcium metabolism	0.013	0.987	0.000
M19.97 Arthrosis, unspecified (Ankle and foot)	0.010	0.990	0.000
O48 Prolonged pregnancy	0.010	0.990	0.000
Z98.8 Other specified postsurgical states	0.008	0.992	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.007	0.993	0.000
R13 Dysphagia	0.000	0.993	0.007
M24.07 Loose body in joint (Ankle and foot)	0.006	0.994	0.000
M24.0 Loose body in joint	0.006	0.994	0.000
T90.4 Sequelae of injury of eye and orbit	0.006	0.994	0.000
M35.3 Polymyalgia rheumatica	0.006	0.994	0.000
M24 Other specific joint derangements	0.006	0.994	0.000
M24.1 Other articular cartilage disorders	0.006	0.994	0.000
T90 Sequelae of injuries of head	0.006	0.994	0.000
M35 Other systemic involvement of connective tissue	0.005	0.994	0.000
T90.9 Sequelae of unspecified injury of head	0.005	0.995	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.005	0.995	0.000
M35.0 Sicca syndrome [Sjogren]	0.005	0.995	0.000
M24.2 Disorder of ligament	0.005	0.995	0.000
Z98.0 Intestinal bypass and anastomosis status	0.005	0.995	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.005	0.995	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.005	0.995	0.000
Z98 Other postsurgical states	0.005	0.995	0.000
M24.02 Loose body in joint (Upper arm)	0.005	0.995	0.000
E11.4 With neurological complications	0.000	0.995	0.005
M24.09 Loose body in joint (Site unspecified)	0.005	0.995	0.000
M24.08 Loose body in joint (Other)	0.005	0.995	0.000
M24.06 Loose body in joint-Lower leg	0.005	0.995	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.005	0.995	0.000
M24.04 Loose body in joint (Hand)	0.005	0.995	0.000
M24.03 Loose body in joint (Forearm)	0.005	0.995	0.000
M24.01 Loose body in joint (Shoulder region)	0.005	0.995	0.000
M24.00 Loose body in joint (Multiple sites)	0.005	0.995	0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.000	0.995	0.005
T90.8 Sequelae of other specified injuries of head	0.005	0.995	0.000
M24.9 Joint derangement, unspecified	0.004	0.995	0.000
M24.7 Protrusio acetabuli	0.004	0.995	0.000
M24.6 Ankylosis of joint	0.004	0.995	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.004	0.995	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.005	0.995	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.995	0.005
M24.27 Disorder of ligament (Ankle and foot)	0.004	0.995	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.004	0.995	0.000
M24.18 Other articular cartilage disorders (Other)	0.004	0.995	0.000
M24.14 Other articular cartilage disorders (Hand)	0.004	0.995	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.004	0.995	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.004	0.995	0.000
F10.0 Acute intoxication	0.000	0.995	0.005
Z98.1 Arthrodesis status	0.004	0.995	0.000
T92 Sequelae of injuries of upper limb	0.004	0.996	0.000
M24.5 Contracture of joint	0.004	0.996	0.000
M24.24 Disorder of ligament (Hand)	0.004	0.996	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.004	0.996	0.000
M24.23 Disorder of ligament (Forearm)	0.004	0.996	0.000
M20.4 Other hammer toe(s) (acquired)	0.004	0.996	0.000
T90.3 Sequelae of injury of cranial nerves	0.004	0.996	0.000
T90.1 Sequelae of open wound of head	0.004	0.996	0.000
T90.0 Sequelae of superficial injury of head	0.004	0.996	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.996	0.004
M35.9 Systemic involvement of connective tissue, unspecified	0.004	0.996	0.000
M35.8 Other specified systemic involvement of connective tissue	0.004	0.996	0.000
M35.7 Hypermobility syndrome	0.004	0.996	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.004	0.996	0.000
M35.5 Multifocal fibrosclerosis	0.004	0.996	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.004	0.996	0.000
M35.2 Behcet's disease	0.004	0.996	0.000
M35.1 Other overlap syndromes	0.004	0.996	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.004	0.996	0.000
T43.2 Other and unspecified antidepressants	0.000	0.996	0.004
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.004	0.996	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.004	0.996	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.004	0.996	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.004	0.996	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.004	0.996	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.004	0.996	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.004	0.996	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.004	0.996	0.000
M24.29 Disorder of ligament (Site unspecified)	0.004	0.996	0.000
M24.28 Disorder of ligament (Other)	0.004	0.996	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.004	0.996	0.000
M24.22 Disorder of ligament (Upper arm)	0.004	0.996	0.000
M24.21 Disorder of ligament (Shoulder region)	0.004	0.996	0.000
M24.20 Disorder of ligament (Multiple sites)	0.004	0.996	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.004	0.996	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.004	0.996	0.000
T90.5 Sequelae of intracranial injury	0.004	0.996	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.004	0.996	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.004	0.996	0.000
T93 Sequelae of injuries of lower limb	0.004	0.996	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
M21 Other acquired deformities of limbs	0.004	0.996	0.000
M20-M25 Other joint disorders	0.004	0.996	0.000
M24.26 Disorder of ligament (Lower leg)	0.004	0.996	0.000
T92.0 Sequelae of open wound of upper limb	0.004	0.996	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.003	0.996	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.003	0.996	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.003	0.996	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.003	0.996	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.003	0.996	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.003	0.996	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.003	0.996	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.003	0.996	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.003	0.996	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.003	0.996	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.003	0.996	0.000
M24.68 Ankylosis of joint (Other)	0.003	0.996	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.003	0.996	0.000
M24.66 Ankylosis of joint (Lower leg)	0.003	0.996	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.003	0.996	0.000
M24.64 Ankylosis of joint (Hand)	0.003	0.996	0.000
M24.63 Ankylosis of joint (Forearm)	0.003	0.996	0.000
M24.62 Ankylosis of joint (Upper arm)	0.003	0.996	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.003	0.996	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.003	0.996	0.000
M24.79 Protrusio acetabuli-Site unspec	0.003	0.996	0.000
M24.78 Protrusio acetabuli-Other	0.003	0.996	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.003	0.996	0.000
M24.76 Protrusio acetabuli-Lower leg	0.003	0.996	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.003	0.996	0.000
M24.74 Protrusio acetabuli-Hand	0.003	0.996	0.000
M24.73 Protrusio acetabuli-Forearm	0.003	0.996	0.000
M24.72 Protrusio acetabuli-Upper arm	0.003	0.996	0.000
M24.71 Protrusio acetabuli-Shldr region	0.003	0.996	0.000
M24.70 Protrusio acetabuli-Mult sites	0.003	0.996	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.003	0.996	0.000
M24.98 Joint derangement, unspecified (Other)	0.003	0.996	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.003	0.996	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.003	0.996	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.003	0.996	0.000
M24.94 Joint derangement, unspecified (Hand)	0.003	0.996	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.003	0.996	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.003	0.996	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.003	0.996	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.003	0.996	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.003	0.996	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.003	0.996	0.000
T91 Sequelae of injuries of neck and trunk	0.003	0.996	0.000
M24.51 Contracture of joint (Shoulder region)	0.003	0.996	0.000
M21.0 Valgus deformity, not elsewhere classified	0.003	0.996	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.003	0.996	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.996	0.003
T92.9 Sequelae of unspecified injury of upper limb	0.003	0.996	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.003	0.996	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.003	0.996	0.000
M24.59 Contracture of joint (Site unspecified)	0.003	0.997	0.000
M24.58 Contracture of joint (Other)	0.003	0.997	0.000
M24.57 Contracture of joint (Ankle and foot)	0.003	0.997	0.000
M24.56 Contracture of joint (Lower leg)	0.003	0.997	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.003	0.997	0.000
M24.53 Contracture of joint (Forearm)	0.003	0.997	0.000
M24.52 Contracture of joint (Upper arm)	0.003	0.997	0.000
M24.50 Contracture of joint (Multiple sites)	0.003	0.997	0.000
M33 Dermatopolymyositis	0.003	0.997	0.000
T95 Sequelae of burns, corrosions and frostbite	0.003	0.997	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.003	0.997	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.003	0.997	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.003	0.997	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.003	0.997	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.003	0.997	0.000
K74.6 Other and unspecified cirrhosis of liver	0.000	0.997	0.003
T98 Sequelae of other and unspecified effects of external causes	0.003	0.997	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.003	0.997	0.000
T43.9 Psychotropic drug, unspecified	0.000	0.997	0.003
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.997	0.003
T43.6 Psychostimulants with abuse potential	0.000	0.997	0.003
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.997	0.003
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.997	0.003
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.003	0.997	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.003	0.997	0.000
M33.1 Other dermatomyositis	0.003	0.997	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.003	0.997	0.000
M21.2 Flexion deformity	0.003	0.997	0.000
M24.54 Contracture of joint (Hand)	0.003	0.997	0.000
M21.4 Flat foot [pes planus] (acquired)	0.003	0.997	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.997	0.003
T92.1 Sequelae of fracture of arm	0.003	0.997	0.000
M21.6 Other acquired deformities of ankle and foot	0.003	0.997	0.000
M21.27 Flexion deformity (Ankle and foot)	0.003	0.997	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.003	0.997	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.003	0.997	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.003	0.997	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.003	0.997	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.003	0.997	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.003	0.997	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.003	0.997	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.003	0.997	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.003	0.997	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.003	0.997	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.003	0.997	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.003	0.997	0.000
T93.0 Sequelae of open wound of lower limb	0.003	0.997	0.000
M22 Disorders of patella	0.003	0.997	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.997	0.003
M21.9 Acquired deformity of limb, unspecified	0.003	0.997	0.000
M21.8 Other specified acquired deformities of limbs	0.003	0.997	0.000
M21.7 Unequal limb length (acquired)	0.003	0.997	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.003	0.997	0.000
M32 Systemic lupus erythematosus	0.003	0.997	0.000
M30 Polyarteritis nodosa and related conditions	0.003	0.997	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.003	0.997	0.000
R22.9 Localised swelling, mass and lump, unspecified	0.003	0.997	0.000
Z83.5 Family history of eye and ear disorders	0.000	0.997	0.003
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.997	0.003
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.003	0.997	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.003	0.997	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.003	0.997	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.003	0.997	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.003	0.997	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.003	0.997	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.003	0.997	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.003	0.997	0.000
Z98.2 Presence of cerebrospinal fluid drainage device	0.003	0.997	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.003	0.997	0.000
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.003	0.997	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.003	0.997	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.003	0.997	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.003	0.997	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.003	0.997	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.003	0.997	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.003	0.997	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.003	0.997	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.003	0.997	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.003	0.997	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.997	0.003
T91.1 Sequelae of fracture of spine	0.003	0.997	0.000
M33.9 Dermatopolymyositis, unspecified	0.003	0.997	0.000
M33.0 Juvenile dermatomyositis	0.003	0.997	0.000
T94.1 Sequelae of injuries, not specified by body region	0.003	0.997	0.000
T94.0 Sequelae of injuries involving multiple body regions	0.003	0.997	0.000
T95.9 Sequelae of unspecified burn, corrosion and frostbite	0.003	0.997	0.000
T95.8 Sequelae of other specified burn, corrosion and frostbite	0.003	0.997	0.000
T95.4 Sequelae of burn and corrosion classifiable only according to extent of body surface involved	0.003	0.997	0.000
T95.3 Sequelae of burn, corrosion and frostbite of lower limb	0.003	0.997	0.000
T95.2 Sequelae of burn, corrosion and frostbite of upper limb	0.003	0.997	0.000
T95.1 Sequelae of burn, corrosion and frostbite of trunk	0.003	0.997	0.000
T95.0 Sequelae of burn, corrosion and frostbite of head and neck	0.003	0.997	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.003	0.997	0.000
T93.1 Sequelae of fracture of femur	0.003	0.997	0.000
M22.2 Patellofemoral disorders	0.003	0.997	0.000
M33.2 Polymyositis	0.003	0.997	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.003	0.997	0.000
N88.2 Stricture and stenosis of cervix uteri	0.000	0.997	0.003
T91.3 Sequelae of injury of spinal cord	0.003	0.997	0.000
T40.2 Other opioids	0.000	0.997	0.003
T98.2 Sequelae of certain early complications of trauma	0.002	0.997	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.002	0.997	0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.002	0.997	0.000
T51.0 Ethanol	0.000	0.997	0.003
T93.9 Sequelae of unspecified injury of lower limb	0.003	0.997	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.997	0.003
O62.2 Other uterine inertia	0.003	0.997	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.997	0.003
M21.29 Flexion deformity (Site unspecified)	0.002	0.997	0.000
M21.28 Flexion deformity (Other)	0.002	0.997	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.002	0.997	0.000
M21.24 Flexion deformity (Hand)	0.002	0.997	0.000
M21.23 Flexion deformity (Forearm)	0.002	0.997	0.000
M21.22 Flexion deformity (Upper arm)	0.002	0.997	0.000
M21.21 Flexion deformity (Shoulder region)	0.002	0.997	0.000
M21.20 Flexion deformity (Multiple sites)	0.002	0.997	0.000
M31 Other necrotising vasculopathies	0.003	0.997	0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.002	0.997	0.000
M21.48 Flat foot [pes planus] (acquired)-Other	0.002	0.997	0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.002	0.997	0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.002	0.997	0.000
M21.44 Flat foot [pes planus] (acquired)-Hand	0.002	0.997	0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.002	0.997	0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.002	0.997	0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.002	0.997	0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.002	0.997	0.000
T40.4 Other synthetic narcotics	0.000	0.997	0.003
M21.1 Varus deformity, not elsewhere classified	0.002	0.997	0.000
T93.2 Sequelae of other fractures of lower limb	0.002	0.997	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.002	0.997	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.002	0.997	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.002	0.997	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.002	0.997	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.002	0.997	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.002	0.997	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.002	0.997	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.002	0.997	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.002	0.997	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.002	0.997	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.002	0.997	0.000
M21.3 Wrist or foot drop (acquired)	0.002	0.997	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.997	0.002
D05.9 Carcinoma in situ of breast, unspecified	0.000	0.997	0.002
D05.1 Intraductal carcinoma in situ	0.000	0.997	0.002
M34 Systemic sclerosis	0.002	0.997	0.000
T42.4 Benzodiazepines	0.000	0.998	0.002
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.002	0.998	0.000
M22.1 Recurrent subluxation of patella	0.002	0.998	0.000
M22.9 Disorder of patella, unspecified	0.002	0.998	0.000
M22.0 Recurrent dislocation of patella	0.002	0.998	0.000
M21.79 Unequal limb length (acquired) (Site unspecified)	0.002	0.998	0.000
M21.78 Unequal limb length (acquired)-Other	0.002	0.998	0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.002	0.998	0.000
M21.76 Unequal limb length (acquired) (Lower leg)	0.002	0.998	0.000
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.002	0.998	0.000
M21.74 Unequal limb length (acquired) (Hand)	0.002	0.998	0.000
M21.73 Unequal limb length (acquired) (Forearm)	0.002	0.998	0.000
M21.72 Unequal limb length (acquired) (Upper arm)	0.002	0.998	0.000
M21.71 Unequal limb length (acquired)-Shldr region	0.002	0.998	0.000
M21.70 Unequal limb length (acquired) (Multiple sites)	0.002	0.998	0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.002	0.998	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.002	0.998	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.002	0.998	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.002	0.998	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.002	0.998	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.002	0.998	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.002	0.998	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.002	0.998	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.002	0.998	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.002	0.998	0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.002	0.998	0.000
M21.98 Acquired deformity of limb, unspecified-Other	0.002	0.998	0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.002	0.998	0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.002	0.998	0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M21.94 Acquired deformity of limb, unspecified (Hand)	0.002	0.998	0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.002	0.998	0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.002	0.998	0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.002	0.998	0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.002	0.998	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.002	0.998	0.000
M32.8 Other forms of systemic lupus erythematosus	0.002	0.998	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.002	0.998	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.002	0.998	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.002	0.998	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.002	0.998	0.000
M36.3 Arthropathy in other blood disorders	0.002	0.998	0.000
M36.2 Haemophilic arthropathy	0.002	0.998	0.000
M36.1 Arthropathy in neoplastic disease	0.002	0.998	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.002	0.998	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.998	0.002
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.998	0.002
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.998	0.002
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.998	0.002
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.998	0.002
T36 Poisoning by systemic antibiotics	0.000	0.998	0.002
M30.8 Other conditions related to polyarteritis nodosa	0.002	0.998	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.002	0.998	0.000
M30.2 Juvenile polyarteritis	0.002	0.998	0.000
M30.0 Polyarteritis nodosa	0.002	0.998	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.002	0.998	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.000	0.998	0.002
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.998	0.002
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
M22.4 Chondromalacia patellae	0.002	0.998	0.000
M22.3 Other derangements of patella	0.002	0.998	0.000
M21.26 Flexion deformity (Lower leg)	0.002	0.998	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.998	0.002
T40.8 Lysergide [LSD]	0.000	0.998	0.002
T40.7 Cannabis (derivatives)	0.000	0.998	0.002
T40.5 Cocaine	0.000	0.998	0.002
T40.3 Methadone	0.000	0.998	0.002
T40.1 Heroin	0.000	0.998	0.002
T40.0 Opium	0.000	0.998	0.002
C73 Malignant neoplasm of thyroid gland	0.002	0.998	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.998	0.002
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.998	0.002
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M22.8 Other disorders of patella	0.002	0.998	0.000
Y57.9 Drug or medicament, unspecified	0.002	0.998	0.000
Z35.5 Supervision of elderly primigravida	0.002	0.998	0.000
F10.4 Withdrawal state with delirium	0.000	0.998	0.002
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.998	0.002
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.998	0.002
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.998	0.002
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.998	0.002
T42.3 Barbiturates	0.000	0.998	0.002
T42.2 Succinimides and oxazolidinediones	0.000	0.998	0.002
T42.0 Hydantoin derivatives	0.000	0.998	0.002
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.998	0.002
F10.3 Withdrawal state	0.000	0.998	0.002
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.998	0.002
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.998	0.002
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.998	0.002
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.998	0.002
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.998	0.002
T44.0 Anticholinesterase agents	0.000	0.998	0.002
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.998	0.002
M31.9 Necrotising vasculopathy, unspecified	0.002	0.998	0.000
M31.8 Other specified necrotising vasculopathies	0.002	0.998	0.000
M31.7 Microscopic polyangiitis	0.002	0.998	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.002	0.998	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.002	0.998	0.000
M31.2 Lethal midline granuloma	0.002	0.998	0.000
M31.1 Thrombotic microangiopathy	0.002	0.998	0.000
M31.0 Hypersensitivity angiitis	0.002	0.998	0.000
T40.6 Other and unspecified narcotics	0.000	0.998	0.002
D05 Carcinoma in situ of breast	0.000	0.998	0.002
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.002	0.998	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.002	0.998	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.002	0.998	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.002	0.998	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.002	0.998	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.002	0.998	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.002	0.998	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.002	0.998	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.002	0.998	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.002	0.998	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.002	0.998	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.002	0.998	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.002	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.998	0.002
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.998	0.002
T46.7 Peripheral vasodilators	0.000	0.998	0.002
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.002
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.998	0.002
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.998	0.002
T46.1 Calcium-channel blockers	0.000	0.998	0.002
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.998	0.002
M34.8 Other forms of systemic sclerosis	0.002	0.998	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.002	0.998	0.000
M34.0 Progressive systemic sclerosis	0.002	0.998	0.000
M20 Acquired deformities of fingers and toes	0.002	0.998	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.002	0.998	0.000
M22.10 Recurrent subluxation of patella, unspecified knee	0.002	0.998	0.000
F10.2 Dependence syndrome	0.000	0.998	0.002
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.002	0.998	0.000
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.002	0.998	0.000
T36.9 Systemic antibiotic, unspecified	0.000	0.998	0.002
T36.8 Other systemic antibiotics	0.000	0.998	0.002
T36.7 Antifungal antibiotics, systemically used	0.000	0.998	0.002
T36.6 Rifamycins	0.000	0.998	0.002
T36.5 Aminoglycosides	0.000	0.998	0.002
T36.4 Tetracyclines	0.000	0.998	0.002
T36.3 Macrolides	0.000	0.998	0.002
T36.2 Chloramphenicol group	0.000	0.998	0.002
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.998	0.002
T36.0 Penicillins	0.000	0.998	0.002
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.998	0.002
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.998	0.002
T37.5 Antiviral drugs	0.000	0.998	0.002
T37.4 Anthelminthics	0.000	0.998	0.002
T37.3 Other antiprotozoal drugs	0.000	0.998	0.002
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.998	0.002
T37.1 Antimycobacterial drugs	0.000	0.998	0.002
T37.0 Sulphonamides	0.000	0.998	0.002
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
T39.0 Salicylates	0.000	0.998	0.002
T41.5 Therapeutic gases	0.000	0.998	0.002
T41.4 Anaesthetic, unspecified	0.000	0.998	0.002
T41.3 Local anaesthetics	0.000	0.998	0.002
T41.2 Other and unspecified general anaesthetics	0.000	0.998	0.002
T41.1 Intravenous anaesthetics	0.000	0.998	0.002
T41.0 Inhaled anaesthetics	0.000	0.998	0.002
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.998	0.002
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.998	0.002
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.998	0.002
T47.7 Emetics	0.000	0.998	0.002
T47.6 Antidiarrhoeal drugs	0.000	0.998	0.002
T47.5 Digestants	0.000	0.998	0.002
T47.4 Other laxatives	0.000	0.998	0.002
T47.3 Saline and osmotic laxatives	0.000	0.998	0.002
T47.2 Stimulant laxatives	0.000	0.998	0.002
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.998	0.002
T47.0 Histamine H(2)-receptor antagonists	0.000	0.998	0.002
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.998	0.002
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.998	0.002
T48.5 Anti-common-cold drugs	0.000	0.998	0.002
T48.4 Expectorants	0.000	0.998	0.002
T48.3 Antitussives	0.000	0.998	0.002
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.998	0.002
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.998	0.002
T48.0 Oxytocic drugs	0.000	0.998	0.002
T49.9 Topical agent, unspecified	0.000	0.998	0.002
T49.8 Other topical agents	0.000	0.998	0.002
T49.7 Dental drugs, topically applied	0.000	0.998	0.002
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.998	0.002
T49.5 Ophthalmological drugs and preparations	0.000	0.998	0.002
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.998	0.002
T49.3 Emollients, demulcents and protectants	0.000	0.998	0.002
T49.2 Local astringents and local detergents	0.000	0.998	0.002
T49.1 Antipruritics	0.000	0.998	0.002
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.998	0.002
F10.9 Unspecified mental and behavioural disorder	0.000	0.998	0.002
F10.8 Other mental and behavioural disorders	0.000	0.998	0.002
F10.7 Residual and late-onset psychotic disorder	0.000	0.998	0.002
F10.6 Amnesic syndrome	0.000	0.998	0.002
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.998	0.002
M31.6 Other giant cell arteritis	0.002	0.998	0.000
T38.9 Other and unspecified hormone antagonists	0.000	0.998	0.002
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.998	0.002
T38.7 Androgens and anabolic congeners	0.000	0.998	0.002
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations