TreeWAS – Variant ID: rs3731896

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.938	0.062
K74.6 Other and unspecified cirrhosis of liver	0.036	0.964	0.000
K74 Fibrosis and cirrhosis of liver	0.028	0.972	0.000
K74.3 Primary biliary cirrhosis	0.027	0.973	0.000
K74.5 Biliary cirrhosis, unspecified	0.022	0.978	0.000
K74.4 Secondary biliary cirrhosis	0.020	0.980	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.020	0.980	0.000
K74.1 Hepatic sclerosis	0.020	0.980	0.000
K74.0 Hepatic fibrosis	0.017	0.982	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.016	0.984	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.015	0.985	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.015	0.985	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.015	0.985	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.012	0.987	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.011	0.988	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.011	0.989	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.011	0.989	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.011	0.989	0.000
K92.9 Disease of digestive system, unspecified	0.009	0.991	0.000
C71.9 Brain, unspecified	0.000	0.991	0.009
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.008	0.991	0.000
M84 Disorders of continuity of bone	0.008	0.992	0.000
C71 Malignant neoplasm of brain	0.000	0.992	0.008
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.007	0.993	0.000
M84.4 Pathological fracture, not elsewhere classified	0.007	0.993	0.000
C71.8 Overlapping lesion of brain	0.000	0.993	0.007
C71.3 Parietal lobe	0.000	0.993	0.007
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.000	0.994	0.006
C71.4 Occipital lobe	0.000	0.994	0.006
M84.3 Stress fracture, not elsewhere classified	0.006	0.994	0.000
C71.1 Frontal lobe	0.000	0.994	0.006
M84.8 Other disorders of continuity of bone	0.006	0.994	0.000
C71.0 Cerebrum, except lobes and ventricles	0.000	0.994	0.006
C71.2 Temporal lobe	0.000	0.994	0.006
L43.9 Lichen planus, unspecified	0.000	0.994	0.006
H49.2 Sixth [abducent] nerve palsy	0.006	0.994	0.000
M84.9 Disorder of continuity of bone, unspecified	0.006	0.994	0.000
M84.2 Delayed union of fracture	0.006	0.994	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.006	0.994	0.000
C71.7 Brain stem	0.000	0.994	0.006
C71.6 Cerebellum	0.000	0.994	0.006
C71.5 Cerebral ventricle	0.000	0.994	0.006
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.005	0.995	0.000
O16 Unspecified maternal hypertension	0.000	0.995	0.005
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.005	0.995	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.005	0.995	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.005	0.995	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.005	0.995	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.005	0.995	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.005	0.995	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.005	0.995	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.005	0.995	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.005	0.995	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.995	0.005
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.005	0.995	0.000
Z52.4 Kidney donor	0.005	0.995	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.995	0.005
Z52.3 Bone marrow donor	0.005	0.995	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.005	0.995	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.005	0.995	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.005	0.995	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.005	0.995	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.005	0.995	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.005	0.995	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.005	0.995	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.005	0.995	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.005	0.995	0.000
H90 Conductive and sensorineural hearing loss	0.005	0.995	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.004	0.995	0.000
M84.88 Other disorders of continuity of bone (Other)	0.004	0.995	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.004	0.995	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.004	0.995	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.004	0.995	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.004	0.995	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.004	0.995	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.004	0.995	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.004	0.995	0.000
H90.2 Conductive hearing loss, unspecified	0.005	0.995	0.000
S72.10 Pertrochanteric fracture (closed)	0.000	0.995	0.005
H90.3 Sensorineural hearing loss, bilateral	0.005	0.995	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.005	0.995	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.996	0.004
M84.29 Delayed union of fracture (Site unspecified)	0.004	0.996	0.000
M84.28 Delayed union of fracture (Other)	0.004	0.996	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.004	0.996	0.000
M84.26 Delayed union of fracture (Lower leg)	0.004	0.996	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.004	0.996	0.000
M84.24 Delayed union of fracture (Hand)	0.004	0.996	0.000
M84.23 Delayed union of fracture (Forearm)	0.004	0.996	0.000
M84.22 Delayed union of fracture (Upper arm)	0.004	0.996	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.004	0.996	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.004	0.996	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.004	0.996	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.004	0.996	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.004	0.996	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.004	0.996	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.004	0.996	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.004	0.996	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.004	0.996	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.004	0.996	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.004	0.996	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
Z52 Donors of organs and tissues	0.004	0.996	0.000
W18.3 Sports and athletics area	0.004	0.996	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.004	0.996	0.000
H90.0 Conductive hearing loss, bilateral	0.004	0.996	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.004	0.996	0.000
O14.9 Preeclampsia, unspecified	0.000	0.996	0.004
L85.8 Other specified epidermal thickening	0.004	0.996	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.004	0.996	0.000
H49 Paralytic strabismus	0.004	0.996	0.000
H90.5 Sensorineural hearing loss, unspecified	0.004	0.996	0.000
O15 Eclampsia	0.000	0.996	0.004
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.000	0.996	0.004
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.996	0.004
Z52.8 Donor of other organs and tissues	0.004	0.996	0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.000	0.996	0.004
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.000	0.996	0.004
H49.9 Paralytic strabismus, unspecified	0.004	0.996	0.000
Z52.0 Blood donor	0.004	0.996	0.000
E87.2 Acidosis	0.000	0.996	0.004
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.004	0.996	0.000
O14.0 Moderate preeclampsia	0.000	0.996	0.004
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.003
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.003
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.003
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.003
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.003
L02 Cutaneous abscess, furuncle and carbuncle	0.000	0.996	0.004
O14.2 HELLP syndrome	0.000	0.997	0.003
D63.0 Anaemia in neoplastic disease	0.000	0.997	0.003
Z52.2 Bone donor	0.003	0.997	0.000
Z52.9 Donor of unspecified organ or tissue	0.003	0.997	0.000
Z52.7 Heart donor	0.003	0.997	0.000
Z52.6 Liver donor	0.003	0.997	0.000
Z52.5 Cornea donor	0.003	0.997	0.000
Z52.1 Skin donor	0.003	0.997	0.000
G81.9 Hemiplegia, unspecified	0.000	0.997	0.003
N82.3 Fistula of vagina to large intestine	0.003	0.997	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.003	0.997	0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.000	0.997	0.003
O14.1 Severe preeclampsia	0.000	0.997	0.003
H49.4 Progressive external ophthalmoplegia	0.003	0.997	0.000
S72.1 Pertrochanteric fracture	0.000	0.997	0.003
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.997	0.003
N82.0 Vesicovaginal fistula	0.003	0.997	0.000
N82 Fistulae involving female genital tract	0.003	0.997	0.000
N82.4 Other female intestinal-genital tract fistulae	0.003	0.997	0.000
C18.7 Sigmoid colon	0.000	0.997	0.003
H49.8 Other paralytic strabismus	0.003	0.997	0.000
H49.3 Total (external) ophthalmoplegia	0.003	0.997	0.000
K04.8 Radicular cyst	0.000	0.997	0.003
O15.9 Eclampsia, unspecified as to time period	0.000	0.997	0.003
O15.2 Eclampsia in the puerperium	0.000	0.997	0.003
O15.1 Eclampsia in labour	0.000	0.997	0.003
O15.0 Eclampsia in pregnancy	0.000	0.997	0.003
E16.2 Hypoglycaemia, unspecified	0.000	0.997	0.003
O12.0 Gestational oedema	0.000	0.997	0.003
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.003	0.997	0.000
O12.2 Gestational oedema with proteinuria	0.000	0.997	0.003
N82.8 Other female genital tract fistulae	0.003	0.997	0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.000	0.997	0.003
M81.20 Osteoporosis of disuse (Multiple sites)	0.003	0.997	0.000
H49.1 Fourth [trochlear] nerve palsy	0.003	0.997	0.000
O12.1 Gestational proteinuria	0.000	0.997	0.003
M80-M85 Disorders of bone density and structure	0.003	0.997	0.000
N82.5 Female genital tract-skin fistulae	0.003	0.997	0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.000	0.997	0.003
H50.2 Vertical strabismus	0.003	0.997	0.000
S72.11 Pertrochanteric fracture (open)	0.000	0.997	0.002
H50.1 Divergent concomitant strabismus	0.003	0.997	0.000
L43 Lichen planus	0.000	0.997	0.003
M81.2 Osteoporosis of disuse	0.003	0.997	0.000
N82.9 Female genital tract fistula, unspecified	0.002	0.997	0.000
N82.2 Fistula of vagina to small intestine	0.002	0.997	0.000
N82.1 Other female urinary-genital tract fistulae	0.002	0.997	0.000
H50 Other strabismus	0.003	0.997	0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.000	0.997	0.002
S01.0 Open wound of scalp	0.000	0.997	0.003
Z95.3 Presence of xenogenic heart valve	0.000	0.997	0.002
Y60.0 During surgical operation	0.002	0.998	0.000
H49.0 Third [oculomotor] nerve palsy	0.002	0.998	0.000
M84.0 Malunion of fracture	0.002	0.998	0.000
M81 Osteoporosis without pathological fracture	0.002	0.998	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.998	0.002
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.998	0.002
H50.8 Other specified strabismus	0.002	0.998	0.000
I67.9 Cerebrovascular disease, unspecified	0.000	0.998	0.002
N93.0 Postcoital and contact bleeding	0.000	0.998	0.002
M83 Adult osteomalacia	0.002	0.998	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.002	0.998	0.000
W18 Other fall on same level	0.002	0.998	0.000
Z39.0 Care and examination immediately after delivery	0.000	0.998	0.002
S72 Fracture of femur	0.000	0.998	0.002
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.002	0.998	0.000
M20.4 Other hammer toe(s) (acquired)	0.000	0.998	0.002
N89.8 Other specified noninflammatory disorders of vagina	0.000	0.998	0.002
G81 Hemiplegia	0.000	0.998	0.002
N48.8 Other specified disorders of penis	0.000	0.998	0.002
L43.3 Subacute (active) lichen planus	0.000	0.998	0.002
L43.2 Lichenoid drug reaction	0.000	0.998	0.002
L43.1 Bullous lichen planus	0.000	0.998	0.002
L43.0 Hypertrophic lichen planus	0.000	0.998	0.002
M81.0 Postmenopausal osteoporosis	0.002	0.998	0.000
S70.0 Contusion of hip	0.000	0.998	0.002
M82 Osteoporosis in diseases classified elsewhere	0.002	0.998	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.000	0.998	0.002
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.998	0.002
M81.29 Osteoporosis of disuse (Site unspecified)	0.002	0.998	0.000
M81.28 Osteoporosis of disuse (Other)	0.002	0.998	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.002	0.998	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.002	0.998	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.002	0.998	0.000
M81.24 Osteoporosis of disuse (Hand)	0.002	0.998	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.002	0.998	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.002	0.998	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.002	0.998	0.000
H50.6 Mechanical strabismus	0.002	0.998	0.000
H50.3 Intermittent heterotropia	0.002	0.998	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.002	0.998	0.000
H50.9 Strabismus, unspecified	0.002	0.998	0.000
M84.09 Malunion of fracture (Site unspecified)	0.002	0.998	0.000
M84.08 Malunion of fracture (Other)	0.002	0.998	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.002	0.998	0.000
M84.02 Malunion of fracture (Upper arm)	0.002	0.998	0.000
M84.00 Malunion of fracture (Multiple sites)	0.002	0.998	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.998	0.002
M81.8 Other osteoporosis	0.002	0.998	0.000
M81.6 Localised osteoporosis [Lequesne]	0.002	0.998	0.000
M81.5 Idiopathic osteoporosis	0.002	0.998	0.000
M81.1 Postoophorectomy osteoporosis	0.002	0.998	0.000
N39.9 Disorder of urinary system, unspecified	0.002	0.998	0.000
H50.4 Other and unspecified heterotropia	0.002	0.998	0.000
S72.8 Fractures of other parts of femur	0.000	0.998	0.002
T40.2 Other opioids	0.000	0.998	0.002
M85 Other disorders of bone density and structure	0.002	0.998	0.000
L43.8 Other lichen planus	0.000	0.998	0.002
S72.0 Fracture of neck of femur	0.000	0.998	0.002
K70-K77 Diseases of liver	0.002	0.998	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.002	0.998	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.000	0.998	0.002
G81.1 Spastic hemiplegia	0.000	0.998	0.002
H50.0 Convergent concomitant strabismus	0.002	0.998	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.002	0.998	0.000
C44.3 Skin of other and unspecified parts of face	0.002	0.998	0.000
G82.2 Paraplegia, unspecified	0.000	0.998	0.002
H50.5 Heterophoria	0.002	0.998	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.002	0.998	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.002	0.998	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.002	0.998	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.002	0.998	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.002	0.998	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.002	0.998	0.000
L65.9 Nonscarring hair loss, unspecified	0.002	0.998	0.000
M83.9 Adult osteomalacia, unspecified	0.002	0.998	0.000
M83.8 Other adult osteomalacia	0.002	0.998	0.000
M83.5 Other drug-induced osteomalacia in adults	0.002	0.998	0.000
M83.4 Aluminum bone disease	0.002	0.998	0.000
M83.3 Adult osteomalacia due to malnutrition	0.002	0.998	0.000
M83.2 Adult osteomalacia due to malabsorption	0.002	0.998	0.000
M83.1 Senile osteomalacia	0.002	0.998	0.000
M83.0 Puerperal osteomalacia	0.002	0.998	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.000	0.998	0.002
W18.5 Trade and service area	0.002	0.998	0.000
S72.80 Fractures of other parts of femur (closed)	0.000	0.998	0.002
S72.7 Multiple fractures of femur	0.000	0.998	0.002
W18.9 Unspecified place	0.002	0.998	0.000
W18.8 Other specified place	0.002	0.998	0.000
W18.4 Street and highway	0.002	0.998	0.000
W18.2 School, other institution and public administrative area	0.002	0.998	0.000
W18.0 Home	0.002	0.998	0.000
W18.7 Farm	0.002	0.998	0.000
W18.6 Industrial and construction area	0.002	0.998	0.000
W18.1 Residential institution	0.002	0.998	0.000
M84.06 Malunion of fracture (Lower leg)	0.001	0.998	0.001
M84.01 Malunion of fracture (Shoulder region)	0.001	0.998	0.001
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.002	0.998	0.000
H51 Other disorders of binocular movement	0.002	0.998	0.000
G81.0 Flaccid hemiplegia	0.000	0.998	0.002
L30.9 Dermatitis, unspecified	0.002	0.998	0.000
Z82.3 Family history of stroke	0.000	0.998	0.002
S72.2 Subtrochanteric fracture	0.000	0.998	0.002
M80 Osteoporosis with pathological fracture	0.002	0.998	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.002	0.998	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.002	0.998	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.002	0.998	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.002	0.998	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.002	0.998	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.002	0.998	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.002	0.998	0.000
S72.00 Fracture of neck of femur (closed)	0.000	0.998	0.002
M82.8 Osteoporosis in other diseases classified elsewhere	0.002	0.998	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.002	0.998	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.002	0.998	0.000
M85.6 Other cyst of bone	0.002	0.998	0.000
M84.04 Malunion of fracture (Hand)	0.001	0.998	0.001
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.998	0.002
M81.4 Drug-induced osteoporosis	0.002	0.998	0.000
C67.6 Ureteric orifice	0.002	0.998	0.000
M85.9 Disorder of bone density and structure, unspecified	0.002	0.998	0.000
C67.9 Bladder, unspecified	0.002	0.998	0.000
N76.8 Other specified inflammation of vagina and vulva	0.000	0.998	0.002
R90.0 Intracranial space-occupying lesion	0.000	0.998	0.002
M84.07 Malunion of fracture (Ankle and foot)	0.001	0.998	0.001
K72.9 Hepatic failure, unspecified	0.002	0.998	0.000
S72.3 Fracture of shaft of femur	0.000	0.998	0.002
K72 Hepatic failure, not elsewhere classified	0.002	0.998	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.001	0.998	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.001	0.998	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.001	0.998	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.001	0.998	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.001	0.998	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.001	0.998	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.001	0.998	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.001	0.998	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.001	0.998	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.001	0.998	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.001	0.998	0.000
M81.58 Idiopathic osteoporosis (Other)	0.001	0.998	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.001	0.998	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.001	0.998	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.001	0.998	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.001	0.998	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.001	0.998	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.001	0.998	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.001	0.998	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.001	0.998	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.001	0.998	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.001	0.998	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.001	0.998	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.001	0.998	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.001	0.998	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.001	0.998	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.001	0.998	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.001	0.998	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.001	0.998	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.001	0.998	0.000
M81.89 Other osteoporosis (Site unspecified)	0.001	0.998	0.000
M81.88 Other osteoporosis (Other)	0.001	0.998	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.001	0.998	0.000
M81.86 Other osteoporosis (Lower leg)	0.001	0.998	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.001	0.998	0.000
M81.84 Other osteoporosis (Hand)	0.001	0.998	0.000
M81.83 Other osteoporosis (Forearm)	0.001	0.998	0.000
M81.82 Other osteoporosis (Upper arm)	0.001	0.998	0.000
M81.81 Other osteoporosis (Shoulder region)	0.001	0.998	0.000
M81.80 Other osteoporosis (Multiple sites)	0.001	0.998	0.000
O73.0 Retained placenta, without haemorrhage	0.002	0.998	0.000
S72.9 Fracture of femur, part unspecified	0.000	0.998	0.002
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.002	0.998	0.000
M85.66 Other cyst of bone (Lower leg)	0.002	0.998	0.000
S72.81 Fractures of other parts of femur (open)	0.000	0.998	0.002
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
M85.5 Aneurysmal bone cyst	0.002	0.998	0.000
M85.4 Solitary bone cyst	0.002	0.998	0.000
M85.3 Osteitis condensans	0.002	0.998	0.000
M85.2 Hyperostosis of skull	0.002	0.998	0.000
M85.1 Skeletal fluorosis	0.002	0.998	0.000
K71 Toxic liver disease	0.002	0.998	0.000
S72.01 Fracture of neck of femur (open)	0.000	0.998	0.002
K77 Liver disorders in diseases classified elsewhere	0.002	0.998	0.000
M85.68 Other cyst of bone (Other)	0.002	0.998	0.000
O47.9 False labour, unspecified	0.000	0.998	0.002
C67 Malignant neoplasm of bladder	0.002	0.998	0.000
C70 Malignant neoplasm of meninges	0.000	0.998	0.002
S70 Superficial injury of hip and thigh	0.000	0.998	0.002
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.998	0.002
M82.1 Osteoporosis in endocrine disorders	0.001	0.998	0.000
S72.4 Fracture of lower end of femur	0.000	0.998	0.002
C67.8 Overlapping lesion of bladder	0.002	0.998	0.000
C67.3 Anterior wall of bladder	0.002	0.998	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.001	0.998	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.998	0.002
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M83.09 Puerperal osteomalacia (Site unspecified)	0.001	0.998	0.000
M83.08 Puerperal osteomalacia (Other)	0.001	0.998	0.000
M83.07 Puerperal osteomalacia (Ankle and foot)	0.001	0.998	0.000
M83.06 Puerperal osteomalacia (Lower leg)	0.001	0.998	0.000
M83.05 Puerperal osteomalacia (Pelvic region and thigh)	0.001	0.998	0.000
M83.04 Puerperal osteomalacia (Hand)	0.001	0.998	0.000
M83.03 Puerperal osteomalacia (Forearm)	0.001	0.998	0.000
M83.02 Puerperal osteomalacia (Upper arm)	0.001	0.998	0.000
M83.01 Puerperal osteomalacia (Shoulder region)	0.001	0.998	0.000
M83.00 Puerperal osteomalacia (Multiple sites)	0.001	0.998	0.000
M83.19 Senile osteomalacia (Site unspecified)	0.001	0.998	0.000
M83.18 Senile osteomalacia (Other)	0.001	0.998	0.000
M83.17 Senile osteomalacia (Ankle and foot)	0.001	0.998	0.000
M83.16 Senile osteomalacia (Lower leg)	0.001	0.998	0.000
M83.15 Senile osteomalacia (Pelvic region and thigh)	0.001	0.998	0.000
M83.14 Senile osteomalacia (Hand)	0.001	0.998	0.000
M83.13 Senile osteomalacia (Forearm)	0.001	0.998	0.000
M83.12 Senile osteomalacia (Upper arm)	0.001	0.998	0.000
M83.11 Senile osteomalacia (Shoulder region)	0.001	0.998	0.000
M83.10 Senile osteomalacia (Multiple sites)	0.001	0.998	0.000
M83.29 Adult osteomalacia due to malabsorption (Site unspecified)	0.001	0.998	0.000
M83.28 Adult osteomalacia due to malabsorption (Other)	0.001	0.998	0.000
M83.27 Adult osteomalacia due to malabsorption (Ankle and foot)	0.001	0.998	0.000
M83.26 Adult osteomalacia due to malabsorption (Lower leg)	0.001	0.998	0.000
M83.25 Adult osteomalacia due to malabsorption (Pelvic region and thigh)	0.001	0.998	0.000
M83.24 Adult osteomalacia due to malabsorption (Hand)	0.001	0.998	0.000
M83.23 Adult osteomalacia due to malabsorption (Forearm)	0.001	0.998	0.000
M83.22 Adult osteomalacia due to malabsorption (Upper arm)	0.001	0.998	0.000
M83.21 Adult osteomalacia due to malabsorption (Shoulder region)	0.001	0.998	0.000
M83.20 Adult osteomalacia due to malabsorption (Multiple sites)	0.001	0.998	0.000
M83.39 Adult osteomalacia due to malnutrition (Site unspecified)	0.001	0.998	0.000
M83.38 Adult osteomalacia due to malnutrition (Other)	0.001	0.998	0.000
M83.37 Adult osteomalacia due to malnutrition (Ankle and foot)	0.001	0.998	0.000
M83.36 Adult osteomalacia due to malnutrition (Lower leg)	0.001	0.998	0.000
M83.35 Adult osteomalacia due to malnutrition (Pelvic region and thigh)	0.001	0.998	0.000
M83.34 Adult osteomalacia due to malnutrition (Hand)	0.001	0.998	0.000
M83.33 Adult osteomalacia due to malnutrition (Forearm)	0.001	0.998	0.000
M83.32 Adult osteomalacia due to malnutrition (Upper arm)	0.001	0.998	0.000
M83.31 Adult osteomalacia due to malnutrition (Shoulder region)	0.001	0.998	0.000
M83.30 Adult osteomalacia due to malnutrition (Multiple sites)	0.001	0.998	0.000
M83.49 Aluminium bone disease (Site unspecified)	0.001	0.998	0.000
M83.48 Aluminium bone disease (Other)	0.001	0.998	0.000
M83.47 Aluminium bone disease (Ankle and foot)	0.001	0.998	0.000
M83.46 Aluminium bone disease (Lower leg)	0.001	0.998	0.000
M83.45 Aluminium bone disease (Pelvic region and thigh)	0.001	0.998	0.000
M83.44 Aluminium bone disease (Hand)	0.001	0.998	0.000
M83.43 Aluminium bone disease (Forearm)	0.001	0.998	0.000
M83.42 Aluminium bone disease (Upper arm)	0.001	0.998	0.000
M83.41 Aluminium bone disease (Shoulder region)	0.001	0.998	0.000
M83.40 Aluminium bone disease (Multiple sites)	0.001	0.998	0.000
M83.59 Other drug-induced osteomalacia in adults (Site unspecified)	0.001	0.998	0.000
M83.58 Other drug-induced osteomalacia in adults (Other)	0.001	0.998	0.000
M83.57 Other drug-induced osteomalacia in adults (Ankle and foot)	0.001	0.998	0.000
M83.56 Other drug-induced osteomalacia in adults (Lower leg)	0.001	0.998	0.000
M83.55 Other drug-induced osteomalacia in adults (Pelvic region and thigh)	0.001	0.998	0.000
M83.54 Other drug-induced osteomalacia in adults (Hand)	0.001	0.998	0.000
M83.53 Other drug-induced osteomalacia in adults (Forearm)	0.001	0.998	0.000
M83.52 Other drug-induced osteomalacia in adults (Upper arm)	0.001	0.998	0.000
M83.51 Other drug-induced osteomalacia in adults (Shoulder region)	0.001	0.998	0.000
M83.50 Other drug-induced osteomalacia in adults (Multiple sites)	0.001	0.998	0.000
M83.89 Other adult osteomalacia (Site unspecified)	0.001	0.998	0.000
M83.88 Other adult osteomalacia (Other)	0.001	0.998	0.000
M83.87 Other adult osteomalacia (Ankle and foot)	0.001	0.998	0.000
M83.86 Other adult osteomalacia (Lower leg)	0.001	0.998	0.000
M83.85 Other adult osteomalacia (Pelvic region and thigh)	0.001	0.998	0.000
M83.84 Other adult osteomalacia (Hand)	0.001	0.998	0.000
M83.83 Other adult osteomalacia (Forearm)	0.001	0.998	0.000
M83.82 Other adult osteomalacia (Upper arm)	0.001	0.998	0.000
M83.81 Other adult osteomalacia (Shoulder region)	0.001	0.998	0.000
M83.80 Other adult osteomalacia (Multiple sites)	0.001	0.998	0.000
M83.99 Adult osteomalacia, unspecified (Site unspecified)	0.001	0.998	0.000
M83.98 Adult osteomalacia, unspecified (Other)	0.001	0.998	0.000
M83.97 Adult osteomalacia, unspecified (Ankle and foot)	0.001	0.998	0.000
M83.96 Adult osteomalacia, unspecified (Lower leg)	0.001	0.998	0.000
M83.95 Adult osteomalacia, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
M83.94 Adult osteomalacia, unspecified (Hand)	0.001	0.998	0.000
M83.93 Adult osteomalacia, unspecified (Forearm)	0.001	0.998	0.000
M83.92 Adult osteomalacia, unspecified (Upper arm)	0.001	0.998	0.000
M83.91 Adult osteomalacia, unspecified (Shoulder region)	0.001	0.998	0.000
M83.90 Adult osteomalacia, unspecified (Multiple sites)	0.001	0.998	0.000
W18.09 Other fall on same level: Home: During unspecified activity	0.001	0.998	0.000
W18.04 Other fall on same level, Home , While resting, sleeping, eating or engaging in other vital activities	0.001	0.998	0.000
W18.22 Other fall on same level; School, other institution and public administrative area; While working for income	0.001	0.998	0.000
W18.49 Other fall on same level; Street and highway; During unspecified activity	0.001	0.998	0.000
W18.48 Other fall on same level; Street and highway; While engaged in other specified activities	0.001	0.998	0.000
W18.89 Other fall on same level; Other specified places; During unspecified activity	0.001	0.998	0.000
W18.99 Other fall on same level; Unspecified place; During unspecified activity	0.001	0.998	0.000
W18.93 Other fall on same level; Unspecified place; While engaged in other types of work	0.001	0.998	0.000
I69 Sequelae of cerebrovascular disease	0.000	0.998	0.002
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.001	0.998	0.000
S72.71 Multiple fractures of femur (open)	0.000	0.998	0.001
S72.70 Multiple fractures of femur (closed)	0.000	0.998	0.001
C67.4 Posterior wall of bladder	0.002	0.998	0.000
H51.9 Disorder of binocular movement, unspecified	0.001	0.998	0.000
H51.8 Other specified disorders of binocular movement	0.001	0.998	0.000
H51.2 Internuclear ophthalmoplegia	0.001	0.998	0.000
H51.1 Convergence insufficiency and excess	0.001	0.998	0.000
H51.0 Palsy of conjugate gaze	0.001	0.998	0.000
M85.64 Other cyst of bone (Hand)	0.001	0.998	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.002	0.998	0.000
S72.21 Subtrochanteric fracture (open)	0.000	0.998	0.001
D68.9 Coagulation defect, unspecified	0.000	0.998	0.002
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.000	0.998	0.002
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.000	0.998	0.001
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)	0.001	0.998	0.000
M82.08 Osteoporosis in multiple myelomatosis (Other)	0.001	0.998	0.000
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)	0.001	0.998	0.000
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)	0.001	0.998	0.000
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)	0.001	0.998	0.000
M82.04 Osteoporosis in multiple myelomatosis (Hand)	0.001	0.998	0.000
M82.03 Osteoporosis in multiple myelomatosis (Forearm)	0.001	0.998	0.000
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)	0.001	0.998	0.000
M82.01 Osteoporosis in multiple myelomatosis (Shoulder region)	0.001	0.998	0.000
M82.00 Osteoporosis in multiple myelomatosis (Multiple sites)	0.001	0.998	0.000
M82.89 Osteoporosis in other diseases classified elsewhere (Site unspecified)	0.001	0.998	0.000
M82.88 Osteoporosis in other diseases classified elsewhere (Other)	0.001	0.998	0.000
M82.87 Osteoporosis in other diseases classified elsewhere (Ankle and foot)	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations