TreeWAS – Variant ID: rs3734905

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E89.0 Postprocedural hypothyroidism	0.053	0.947	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.046	0.954	0.000
E89.3 Postprocedural hypopituitarism	0.037	0.963	0.000
E89.2 Postprocedural hypoparathyroidism	0.037	0.963	0.000
E70-E90 Metabolic disorders	0.034	0.966	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.033	0.967	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.033	0.967	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.033	0.967	0.000
E89.5 Postprocedural testicular hypofunction	0.033	0.967	0.000
E89.4 Postprocedural ovarian failure	0.033	0.967	0.000
E89.1 Postprocedural hypoinsulinaemia	0.033	0.967	0.000
E27.1 Primary adrenocortical insufficiency	0.032	0.968	0.000
E27 Other disorders of adrenal gland	0.032	0.968	0.000
E20-E35 Disorders of other endocrine glands	0.030	0.970	0.000
E86 Volume depletion	0.028	0.972	0.000
E88 Other metabolic disorders	0.028	0.972	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.028	0.972	0.000
E87.7 Fluid overload	0.028	0.972	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.027	0.973	0.000
E23 Hypofunction and other disorders of pituitary gland	0.027	0.973	0.000
E85 Amyloidosis	0.026	0.974	0.000
E87.0 Hyperosmolality and hypernatraemia	0.026	0.974	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.026	0.974	0.000
E84 Cystic fibrosis	0.024	0.975	0.000
E79 Disorders of purine and pyrimidine metabolism	0.024	0.975	0.000
E77 Disorders of glycoprotein metabolism	0.024	0.975	0.000
E76 Disorders of glycosaminoglycan metabolism	0.024	0.975	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.024	0.975	0.000
E72 Other disorders of amino-acid metabolism	0.024	0.975	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.024	0.975	0.000
E70 Disorders of aromatic amino-acid metabolism	0.024	0.975	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.024	0.975	0.000
E27.8 Other specified disorders of adrenal gland	0.024	0.976	0.000
E22 Hyperfunction of pituitary gland	0.024	0.976	0.000
E24 Cushing's syndrome	0.024	0.976	0.000
T43.2 Other and unspecified antidepressants	0.024	0.976	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.024	0.976	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.023	0.976	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.023	0.977	0.000
E23.2 Diabetes insipidus	0.023	0.977	0.000
E74 Other disorders of carbohydrate metabolism	0.023	0.977	0.000
R56.8 Other and unspecified convulsions	0.000	0.977	0.023
E27.2 Addisonian crisis	0.023	0.977	0.000
E27.5 Adrenomedullary hyperfunction	0.023	0.977	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.023	0.977	0.000
E27.0 Other adrenocortical overactivity	0.023	0.977	0.000
E20 Hypoparathyroidism	0.023	0.977	0.000
E88.2 Lipomatosis, not elsewhere classified	0.022	0.978	0.000
E73 Lactose intolerance	0.022	0.978	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.022	0.978	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.022	0.978	0.000
E32 Diseases of thymus	0.022	0.978	0.000
E31 Polyglandular dysfunction	0.022	0.978	0.000
E30 Disorders of puberty, not elsewhere classified	0.022	0.978	0.000
E26 Hyperaldosteronism	0.022	0.978	0.000
E25 Adrenogenital disorders	0.022	0.978	0.000
E23.0 Hypopituitarism	0.022	0.978	0.000
E85.3 Secondary systemic amyloidosis	0.022	0.978	0.000
E27.9 Disorder of adrenal gland, unspecified	0.021	0.979	0.000
E29 Testicular dysfunction	0.021	0.979	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.021	0.979	0.000
E88.9 Metabolic disorder, unspecified	0.020	0.979	0.000
E88.8 Other specified metabolic disorders	0.020	0.979	0.000
E88.3 Tumour lysis syndrome	0.020	0.979	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.020	0.979	0.000
E83 Disorders of mineral metabolism	0.020	0.980	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.020	0.980	0.000
E22.1 Hyperprolactinaemia	0.020	0.980	0.000
E87.4 Mixed disorder of acid-base balance	0.020	0.980	0.000
E85.9 Amyloidosis, unspecified	0.020	0.980	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.020	0.980	0.000
E23.7 Disorder of pituitary gland, unspecified	0.019	0.980	0.000
E23.6 Other disorders of pituitary gland	0.019	0.980	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.019	0.980	0.000
E23.1 Drug-induced hypopituitarism	0.019	0.980	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.019	0.981	0.000
E24.9 Cushing's syndrome, unspecified	0.019	0.981	0.000
E34 Other endocrine disorders	0.019	0.981	0.000
E85.8 Other amyloidosis	0.019	0.981	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.019	0.981	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.019	0.981	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.019	0.981	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.019	0.981	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.019	0.981	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.019	0.981	0.000
E21.0 Primary hyperparathyroidism	0.019	0.981	0.000
E21.3 Hyperparathyroidism, unspecified	0.018	0.982	0.000
E22.0 Acromegaly and pituitary gigantism	0.018	0.982	0.000
E28 Ovarian dysfunction	0.018	0.982	0.000
E87.5 Hyperkalaemia	0.018	0.982	0.000
E40-E46 Malnutrition	0.018	0.982	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.018	0.982	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.018	0.982	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.018	0.982	0.000
E70.3 Albinism	0.018	0.982	0.000
E70.2 Disorders of tyrosine metabolism	0.018	0.982	0.000
E70.1 Other hyperphenylalaninaemias	0.018	0.982	0.000
E70.0 Classical phenylketonuria	0.018	0.982	0.000
E71.3 Disorders of fatty-acid metabolism	0.018	0.982	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.018	0.982	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.018	0.982	0.000
E71.0 Maple-syrup-urine disease	0.018	0.982	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.018	0.982	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.018	0.982	0.000
E72.5 Disorders of glycine metabolism	0.018	0.982	0.000
E72.4 Disorders of ornithine metabolism	0.018	0.982	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.018	0.982	0.000
E72.2 Disorders of urea cycle metabolism	0.018	0.982	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.018	0.982	0.000
E72.0 Disorders of amino-acid transport	0.018	0.982	0.000
E75.6 Lipid storage disorder, unspecified	0.018	0.982	0.000
E75.5 Other lipid storage disorders	0.018	0.982	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.018	0.982	0.000
E75.3 Sphingolipidosis, unspecified	0.018	0.982	0.000
E75.2 Other sphingolipidosis	0.018	0.982	0.000
E75.1 Other gangliosidosis	0.018	0.982	0.000
E75.0 GM2 gangliosidosis	0.018	0.982	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.018	0.982	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.018	0.982	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.018	0.982	0.000
E76.2 Other mucopolysaccharidoses	0.018	0.982	0.000
E76.1 Mucopolysaccharidosis, type II	0.018	0.982	0.000
E76.0 Mucopolysaccharidosis, type I	0.018	0.982	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.018	0.982	0.000
E77.8 Other disorders of glycoprotein metabolism	0.018	0.982	0.000
E77.1 Defects in glycoprotein degradation	0.018	0.982	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.018	0.982	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.018	0.982	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.018	0.982	0.000
E79.1 Lesch-Nyhan syndrome	0.018	0.982	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.018	0.982	0.000
E84.9 Cystic fibrosis, unspecified	0.018	0.982	0.000
E84.8 Cystic fibrosis with other manifestations	0.018	0.982	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.018	0.982	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.018	0.982	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.017	0.982	0.000
E22.8 Other hyperfunction of pituitary gland	0.017	0.982	0.000
E85.4 Organ-limited amyloidosis	0.017	0.982	0.000
E83.5 Disorders of calcium metabolism	0.017	0.983	0.000
E20.9 Hypoparathyroidism, unspecified	0.017	0.983	0.000
E16 Other disorders of pancreatic internal secretion	0.017	0.983	0.000
E24.8 Other Cushing's syndrome	0.017	0.983	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.017	0.983	0.000
E24.3 Ectopic ACTH syndrome	0.017	0.983	0.000
E24.2 Drug-induced Cushing's syndrome	0.017	0.983	0.000
E24.1 Nelson's syndrome	0.017	0.983	0.000
E24.0 Pituitary-dependent Cushing's disease	0.017	0.983	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.017	0.983	0.000
E21.4 Other specified disorders of parathyroid gland	0.017	0.983	0.000
E21.2 Other hyperparathyroidism	0.017	0.983	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.017	0.983	0.000
E80.6 Other disorders of bilirubin metabolism	0.017	0.983	0.000
E80.5 Crigler-Najjar syndrome	0.017	0.983	0.000
E80.3 Defects of catalase and peroxydase	0.017	0.983	0.000
E80.2 Other porphyria	0.017	0.983	0.000
E80.1 Porphyria cutanea tarda	0.017	0.983	0.000
E80.0 Hereditary erythropoietic porphyria	0.017	0.983	0.000
E50-E64 Other nutritional deficiencies	0.017	0.983	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.017	0.983	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.017	0.983	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.017	0.983	0.000
E74.2 Disorders of galactose metabolism	0.017	0.983	0.000
E74.1 Disorders of fructose metabolism	0.017	0.983	0.000
E74.0 Glycogen storage disease	0.017	0.983	0.000
E87.3 Alkalosis	0.017	0.983	0.000
T39.0 Salicylates	0.017	0.983	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.017	0.983	0.000
E20.8 Other hypoparathyroidism	0.016	0.983	0.000
E20.1 Pseudohypoparathyroidism	0.016	0.983	0.000
E20.0 Idiopathic hypoparathyroidism	0.016	0.983	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.016	0.983	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.016	0.984	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.016	0.984	0.000
E73.8 Other lactose intolerance	0.016	0.984	0.000
E73.1 Secondary lactase deficiency	0.016	0.984	0.000
E73.0 Congenital lactase deficiency	0.016	0.984	0.000
T43.9 Psychotropic drug, unspecified	0.016	0.984	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.016	0.984	0.000
T43.6 Psychostimulants with abuse potential	0.016	0.984	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.016	0.984	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.016	0.984	0.000
E80.4 Gilbert's syndrome	0.016	0.984	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.016	0.984	0.000
E25.9 Adrenogenital disorder, unspecified	0.016	0.984	0.000
E25.8 Other adrenogenital disorders	0.016	0.984	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.016	0.984	0.000
E26.9 Hyperaldosteronism, unspecified	0.016	0.984	0.000
E26.8 Other hyperaldosteronism	0.016	0.984	0.000
E26.1 Secondary hyperaldosteronism	0.016	0.984	0.000
E26.0 Primary hyperaldosteronism	0.016	0.984	0.000
E30.9 Disorder of puberty, unspecified	0.016	0.984	0.000
E30.8 Other disorders of puberty	0.016	0.984	0.000
E30.1 Precocious puberty	0.016	0.984	0.000
E30.0 Delayed puberty	0.016	0.984	0.000
E31.9 Polyglandular dysfunction, unspecified	0.016	0.984	0.000
E31.8 Other polyglandular dysfunction	0.016	0.984	0.000
E31.1 Polyglandular hyperfunction	0.016	0.984	0.000
E31.0 Autoimmune polyglandular failure	0.016	0.984	0.000
E32.9 Disease of thymus, unspecified	0.016	0.984	0.000
E32.8 Other diseases of thymus	0.016	0.984	0.000
E32.1 Abscess of thymus	0.016	0.984	0.000
E32.0 Persistent hyperplasia of thymus	0.016	0.984	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.016	0.984	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.016	0.984	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.016	0.984	0.000
T46.1 Calcium-channel blockers	0.016	0.984	0.000
E00-E07 Disorders of thyroid gland	0.016	0.984	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.016	0.984	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.016	0.984	0.000
T40.2 Other opioids	0.016	0.984	0.000
E29.9 Testicular dysfunction, unspecified	0.015	0.984	0.000
E29.8 Other testicular dysfunction	0.015	0.984	0.000
E29.0 Testicular hyperfunction	0.015	0.984	0.000
E15 Nondiabetic hypoglycaemic coma	0.015	0.985	0.000
E04.2 Non-toxic multinodular goitre	0.015	0.985	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.015	0.985	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.015	0.985	0.000
E83.8 Other disorders of mineral metabolism	0.015	0.985	0.000
E83.2 Disorders of zinc metabolism	0.015	0.985	0.000
E83.0 Disorders of copper metabolism	0.015	0.985	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.015	0.985	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.015	0.985	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.015	0.985	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.015	0.985	0.000
T36 Poisoning by systemic antibiotics	0.015	0.985	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.015	0.985	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.015	0.985	0.000
E29.1 Testicular hypofunction	0.015	0.985	0.000
E55 Vitamin D deficiency	0.015	0.985	0.000
E87.2 Acidosis	0.015	0.985	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.015	0.985	0.000
E16.2 Hypoglycaemia, unspecified	0.015	0.985	0.000
T40.4 Other synthetic narcotics	0.014	0.986	0.000
E83.4 Disorders of magnesium metabolism	0.014	0.986	0.000
E04 Other non-toxic goitre	0.014	0.986	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.014	0.986	0.000
T39.4 Antirheumatics, not elsewhere classified	0.014	0.986	0.000
T39.2 Pyrazolone derivatives	0.014	0.986	0.000
E34.8 Other specified endocrine disorders	0.014	0.986	0.000
E34.5 Androgen resistance syndrome	0.014	0.986	0.000
E34.4 Constitutional tall stature	0.014	0.986	0.000
E34.3 Short stature, not elsewhere classified	0.014	0.986	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.014	0.986	0.000
E34.1 Other hypersecretion of intestinal hormones	0.014	0.986	0.000
E73.9 Lactose intolerance, unspecified	0.014	0.986	0.000
E34.0 Carcinoid syndrome	0.014	0.986	0.000
N03.9 Unspecified	0.014	0.986	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.014	0.986	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.014	0.986	0.000
T46.7 Peripheral vasodilators	0.014	0.986	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.014	0.986	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.014	0.986	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.014	0.986	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.014	0.986	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.014	0.986	0.000
J42 Unspecified chronic bronchitis	0.013	0.987	0.000
Z91.5 Personal history of self-harm	0.013	0.987	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.013	0.987	0.000
E28.9 Ovarian dysfunction, unspecified	0.013	0.987	0.000
E28.8 Other ovarian dysfunction	0.013	0.987	0.000
E28.3 Primary ovarian failure	0.013	0.987	0.000
E28.1 Androgen excess	0.013	0.987	0.000
E28.0 Oestrogen excess	0.013	0.987	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.013	0.987	0.000
E45 Retarded development following protein-energy malnutrition	0.013	0.987	0.000
E43 Unspecified severe protein-energy malnutrition	0.013	0.987	0.000
E42 Marasmic kwashiorkor	0.013	0.987	0.000
E41 Nutritional marasmus	0.013	0.987	0.000
E40 Kwashiorkor	0.013	0.987	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.013	0.987	0.000
T40.8 Lysergide [LSD]	0.013	0.987	0.000
T40.7 Cannabis (derivatives)	0.013	0.987	0.000
T40.5 Cocaine	0.013	0.987	0.000
T40.3 Methadone	0.013	0.987	0.000
T40.1 Heroin	0.013	0.987	0.000
T40.0 Opium	0.013	0.987	0.000
E16.1 Other hypoglycaemia	0.013	0.987	0.000
T40.6 Other and unspecified narcotics	0.013	0.987	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.013	0.987	0.000
E55.9 Vitamin D deficiency, unspecified	0.013	0.987	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.013	0.987	0.000
E07 Other disorders of thyroid	0.013	0.987	0.000
J47 Bronchiectasis	0.013	0.987	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.013	0.987	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.013	0.987	0.000
E16.4 Abnormal secretion of gastrin	0.013	0.987	0.000
E16.3 Increased secretion of glucagon	0.013	0.987	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.013	0.987	0.000
E83.3 Disorders of phosphorus metabolism	0.013	0.987	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.012	0.987	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.012	0.987	0.000
E63 Other nutritional deficiencies	0.012	0.987	0.000
E56 Other vitamin deficiencies	0.012	0.987	0.000
E51 Thiamine deficiency	0.012	0.987	0.000
E50 Vitamin A deficiency	0.012	0.987	0.000
E60 Dietary zinc deficiency	0.012	0.987	0.000
E59 Dietary selenium deficiency	0.012	0.987	0.000
E58 Dietary calcium deficiency	0.012	0.987	0.000
E54 Ascorbic acid deficiency	0.012	0.987	0.000
E52 Niacin deficiency [pellagra]	0.012	0.987	0.000
E46 Unspecified protein-energy malnutrition	0.012	0.987	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.012	0.988	0.000
J40-J47 Chronic lower respiratory diseases	0.012	0.988	0.000
T42.1 Iminostilbenes	0.012	0.988	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.012	0.988	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.012	0.988	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.012	0.988	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.012	0.988	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.012	0.988	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.012	0.988	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.012	0.988	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.012	0.988	0.000
T44.0 Anticholinesterase agents	0.012	0.988	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.012	0.988	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.012	0.988	0.000
T47.7 Emetics	0.012	0.988	0.000
T47.6 Antidiarrhoeal drugs	0.012	0.988	0.000
T47.5 Digestants	0.012	0.988	0.000
T47.4 Other laxatives	0.012	0.988	0.000
T47.3 Saline and osmotic laxatives	0.012	0.988	0.000
T47.2 Stimulant laxatives	0.012	0.988	0.000
T47.0 Histamine H(2)-receptor antagonists	0.012	0.988	0.000
E34.9 Endocrine disorder, unspecified	0.011	0.988	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.011	0.988	0.000
E00 Congenital iodine-deficiency syndrome	0.011	0.988	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.011	0.988	0.000
E10-E14 Diabetes mellitus	0.011	0.989	0.000
T36.9 Systemic antibiotic, unspecified	0.011	0.989	0.000
T36.8 Other systemic antibiotics	0.011	0.989	0.000
T36.7 Antifungal antibiotics, systemically used	0.011	0.989	0.000
T36.6 Rifamycins	0.011	0.989	0.000
T36.5 Aminoglycosides	0.011	0.989	0.000
T36.4 Tetracyclines	0.011	0.989	0.000
T36.3 Macrolides	0.011	0.989	0.000
T36.2 Chloramphenicol group	0.011	0.989	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.011	0.989	0.000
T36.0 Penicillins	0.011	0.989	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.011	0.989	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.011	0.989	0.000
T37.5 Antiviral drugs	0.011	0.989	0.000
T37.4 Anthelminthics	0.011	0.989	0.000
T37.3 Other antiprotozoal drugs	0.011	0.989	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.011	0.989	0.000
T37.1 Antimycobacterial drugs	0.011	0.989	0.000
T37.0 Sulphonamides	0.011	0.989	0.000
T41.5 Therapeutic gases	0.011	0.989	0.000
T41.4 Anaesthetic, unspecified	0.011	0.989	0.000
T41.3 Local anaesthetics	0.011	0.989	0.000
T41.2 Other and unspecified general anaesthetics	0.011	0.989	0.000
T41.1 Intravenous anaesthetics	0.011	0.989	0.000
T41.0 Inhaled anaesthetics	0.011	0.989	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.011	0.989	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.011	0.989	0.000
T48.5 Anti-common-cold drugs	0.011	0.989	0.000
T48.4 Expectorants	0.011	0.989	0.000
T48.3 Antitussives	0.011	0.989	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.011	0.989	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.011	0.989	0.000
T48.0 Oxytocic drugs	0.011	0.989	0.000
T49.9 Topical agent, unspecified	0.011	0.989	0.000
T49.8 Other topical agents	0.011	0.989	0.000
T49.7 Dental drugs, topically applied	0.011	0.989	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.011	0.989	0.000
T49.5 Ophthalmological drugs and preparations	0.011	0.989	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.011	0.989	0.000
T49.3 Emollients, demulcents and protectants	0.011	0.989	0.000
T49.2 Local astringents and local detergents	0.011	0.989	0.000
T49.1 Antipruritics	0.011	0.989	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.011	0.989	0.000
E07.9 Disorder of thyroid, unspecified	0.011	0.989	0.000
E65-E68 Obesity and other hyperalimentation	0.011	0.989	0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.000	0.989	0.011
E55.0 Rickets, active	0.011	0.989	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.011	0.989	0.000
T45.8 Other primarily systemic and haematological agents	0.011	0.989	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.011	0.989	0.000
T45.6 Fibrinolysis-affecting drugs	0.011	0.989	0.000
T45.5 Anticoagulants	0.011	0.989	0.000
T45.4 Iron and its compounds	0.011	0.989	0.000
T45.3 Enzymes, not elsewhere classified	0.011	0.989	0.000
T45.2 Vitamins, not elsewhere classified	0.011	0.989	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.011	0.989	0.000
E04.8 Other specified non-toxic goitre	0.010	0.989	0.000
E61 Deficiency of other nutrient elements	0.010	0.989	0.000
T45.0 Antiallergic and antiemetic drugs	0.010	0.990	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.010	0.990	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.010	0.990	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.010	0.990	0.000
T42.3 Barbiturates	0.010	0.990	0.000
T42.2 Succinimides and oxazolidinediones	0.010	0.990	0.000
T42.0 Hydantoin derivatives	0.010	0.990	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.010	0.990	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.000	0.990	0.010
R56 Convulsions, not elsewhere classified	0.000	0.990	0.010
E04.0 Non-toxic diffuse goitre	0.010	0.990	0.000
E44.1 Mild protein-energy malnutrition	0.009	0.990	0.000
E44.0 Moderate protein-energy malnutrition	0.009	0.990	0.000
E28.2 Polycystic ovarian syndrome	0.009	0.990	0.000
E06 Thyroiditis	0.009	0.990	0.000
E07.1 Dyshormogenetic goitre	0.009	0.991	0.000
E07.0 Hypersecretion of calcitonin	0.009	0.991	0.000
E04.9 Non-toxic goitre, unspecified	0.009	0.991	0.000
J40 Bronchitis, not specified as acute or chronic	0.009	0.991	0.000
T38.9 Other and unspecified hormone antagonists	0.009	0.991	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.009	0.991	0.000
T38.7 Androgens and anabolic congeners	0.009	0.991	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.009	0.991	0.000
T38.5 Other oestrogens and progestogens	0.009	0.991	0.000
T38.4 Oral contraceptives	0.009	0.991	0.000
T38.2 Antithyroid drugs	0.009	0.991	0.000
T38.1 Thyroid hormones and substitutes	0.009	0.991	0.000
T38.0 Glucocorticoids and synthetic analogues	0.009	0.991	0.000
E50.9 Vitamin A deficiency, unspecified	0.009	0.991	0.000
E50.8 Other manifestations of vitamin A deficiency	0.009	0.991	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.009	0.991	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.009	0.991	0.000
E50.5 Vitamin A deficiency with night blindness	0.009	0.991	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.009	0.991	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.009	0.991	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.009	0.991	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.009	0.991	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.009	0.991	0.000
E51.9 Thiamine deficiency, unspecified	0.009	0.991	0.000
E51.8 Other manifestations of thiamine deficiency	0.009	0.991	0.000
E51.2 Wernicke's encephalopathy	0.009	0.991	0.000
E51.1 Beriberi	0.009	0.991	0.000
E56.9 Vitamin deficiency, unspecified	0.009	0.991	0.000
E56.8 Deficiency of other vitamins	0.009	0.991	0.000
E56.1 Deficiency of vitamin K	0.009	0.991	0.000
E56.0 Deficiency of vitamin E	0.009	0.991	0.000
E63.9 Nutritional deficiency, unspecified	0.009	0.991	0.000
E63.8 Other specified nutritional deficiencies	0.009	0.991	0.000
E63.1 Imbalance of constituents of food intake	0.009	0.991	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.009	0.991	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.009	0.991	0.000
E64.8 Sequelae of other nutritional deficiencies	0.009	0.991	0.000
E64.3 Sequelae of rickets	0.009	0.991	0.000
E64.2 Sequelae of vitamin C deficiency	0.009	0.991	0.000
E64.1 Sequelae of vitamin A deficiency	0.009	0.991	0.000
E64.0 Sequelae of protein-energy malnutrition	0.009	0.991	0.000
E83.1 Disorders of iron metabolism	0.009	0.991	0.000
E87.6 Hypokalaemia	0.009	0.991	0.000
T50.8 Diagnostic agents	0.009	0.991	0.000
T50.7 Analeptics and opioid receptor antagonists	0.009	0.991	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.009	0.991	0.000
T50.5 Appetite depressants	0.009	0.991	0.000
T50.4 Drugs affecting uric acid metabolism	0.009	0.991	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.009	0.991	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.009	0.991	0.000
T50.1 Loop [high-ceiling] diuretics	0.009	0.991	0.000
T50.0 Mineralocorticoids and their antagonists	0.009	0.991	0.000
K22.8 Other specified diseases of oesophagus	0.000	0.991	0.009
E53 Deficiency of other B group vitamins	0.009	0.991	0.000
E07.8 Other specified disorders of thyroid	0.009	0.991	0.000
J43 Emphysema	0.009	0.991	0.000
J45 Asthma	0.009	0.991	0.000
J45.0 Predominantly allergic asthma	0.009	0.991	0.000
J41 Simple and mucopurulent chronic bronchitis	0.009	0.991	0.000
E14 Unspecified diabetes mellitus	0.009	0.991	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.008	0.991	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.008	0.991	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.008	0.991	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.008	0.991	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.008	0.991	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.008	0.991	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.008	0.991	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.008	0.991	0.000
J18.0 Bronchopneumonia, unspecified	0.009	0.991	0.000
J18 Pneumonia, organism unspecified	0.008	0.992	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.008	0.992	0.000
E12 Malnutrition-related diabetes mellitus	0.008	0.992	0.000
E67 Other hyperalimentation	0.008	0.992	0.000
E68 Sequelae of hyperalimentation	0.008	0.992	0.000
E04.1 Non-toxic single thyroid nodule	0.008	0.992	0.000
E10 Insulin-dependent diabetes mellitus	0.008	0.992	0.000
J18.9 Pneumonia, unspecified	0.008	0.992	0.000
E61.9 Deficiency of nutrient element, unspecified	0.008	0.992	0.000
E61.8 Deficiency of other specified nutrient elements	0.008	0.992	0.000
E61.7 Deficiency of multiple nutrient elements	0.008	0.992	0.000
E61.6 Vanadium deficiency	0.008	0.992	0.000
E61.5 Molybdenum deficiency	0.008	0.992	0.000
E61.4 Chromium deficiency	0.008	0.992	0.000
E61.3 Manganese deficiency	0.008	0.992	0.000
E61.2 Magnesium deficiency	0.008	0.992	0.000
E61.0 Copper deficiency	0.008	0.992	0.000
T39.1 4-Aminophenol derivatives	0.008	0.992	0.000
J46 Status asthmaticus	0.008	0.992	0.000
E14.3 With ophthalmic complications	0.007	0.992	0.000
J43.9 Emphysema, unspecified	0.007	0.993	0.000
E10.9 Without complications	0.007	0.993	0.000
E14.1 With ketoacidosis	0.007	0.993	0.000
R56.0 Febrile convulsions	0.000	0.993	0.007
E03 Other hypothyroidism	0.007	0.993	0.000
E13 Other specified diabetes mellitus	0.007	0.993	0.000
J44 Other chronic obstructive pulmonary disease	0.007	0.993	0.000
E78.8 Other disorders of lipoprotein metabolism	0.007	0.993	0.000
E06.9 Thyroiditis, unspecified	0.007	0.993	0.000
J18.8 Other pneumonia, organism unspecified	0.007	0.993	0.000
E06.5 Other chronic thyroiditis	0.007	0.993	0.000
E06.4 Drug-induced thyroiditis	0.007	0.993	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations