TreeWAS – Variant ID: rs3736228

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M81.99 Osteoporosis, unspecified (Site unspecified)	0.619	0.381	0.000
M81.9 Osteoporosis, unspecified	0.569	0.431	0.000
M81.98 Osteoporosis, unspecified (Other)	0.521	0.479	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.461	0.539	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.459	0.541	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.414	0.586	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.408	0.592	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.408	0.592	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.408	0.592	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.408	0.592	0.000
M81 Osteoporosis without pathological fracture	0.393	0.607	0.000
M81.0 Postmenopausal osteoporosis	0.326	0.674	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.320	0.680	0.000
M81.8 Other osteoporosis	0.282	0.718	0.000
M81.6 Localised osteoporosis [Lequesne]	0.282	0.718	0.000
M81.5 Idiopathic osteoporosis	0.282	0.718	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.282	0.718	0.000
M81.1 Postoophorectomy osteoporosis	0.282	0.718	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.278	0.722	0.000
M81.2 Osteoporosis of disuse	0.267	0.732	0.000
M81.4 Drug-induced osteoporosis	0.253	0.747	0.000
M80-M85 Disorders of bone density and structure	0.246	0.754	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.234	0.766	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.234	0.766	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.234	0.766	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.234	0.766	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.234	0.766	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.234	0.766	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.234	0.766	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.234	0.766	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.234	0.766	0.000
M82 Osteoporosis in diseases classified elsewhere	0.206	0.794	0.000
M84 Disorders of continuity of bone	0.202	0.798	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.202	0.798	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.202	0.798	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.202	0.798	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.202	0.798	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.202	0.798	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.202	0.798	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.202	0.798	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.202	0.798	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.202	0.798	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.202	0.798	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.202	0.798	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.202	0.798	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.202	0.798	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.202	0.798	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.202	0.798	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.202	0.798	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.202	0.798	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.202	0.798	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.202	0.798	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.202	0.798	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.202	0.798	0.000
M81.58 Idiopathic osteoporosis (Other)	0.202	0.798	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.202	0.798	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.202	0.798	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.202	0.798	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.202	0.798	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.202	0.798	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.202	0.798	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.202	0.798	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.202	0.798	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.202	0.798	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.202	0.798	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.202	0.798	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.202	0.798	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.202	0.798	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.202	0.798	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.202	0.798	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.202	0.798	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.202	0.798	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.202	0.798	0.000
M81.89 Other osteoporosis (Site unspecified)	0.202	0.798	0.000
M81.88 Other osteoporosis (Other)	0.202	0.798	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.202	0.798	0.000
M81.86 Other osteoporosis (Lower leg)	0.202	0.798	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.202	0.798	0.000
M81.84 Other osteoporosis (Hand)	0.202	0.798	0.000
M81.83 Other osteoporosis (Forearm)	0.202	0.798	0.000
M81.82 Other osteoporosis (Upper arm)	0.202	0.798	0.000
M81.81 Other osteoporosis (Shoulder region)	0.202	0.798	0.000
M81.80 Other osteoporosis (Multiple sites)	0.202	0.798	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.192	0.808	0.000
M81.28 Osteoporosis of disuse (Other)	0.192	0.808	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.192	0.808	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.192	0.808	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.192	0.808	0.000
M81.24 Osteoporosis of disuse (Hand)	0.192	0.808	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.192	0.808	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.192	0.808	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.192	0.808	0.000
M81.48 Drug-induced osteoporosis (Other)	0.181	0.818	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.181	0.818	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.181	0.818	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.181	0.818	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.181	0.818	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.181	0.818	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.181	0.818	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.181	0.818	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.180	0.820	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.177	0.822	0.000
M82.1 Osteoporosis in endocrine disorders	0.177	0.823	0.000
M83 Adult osteomalacia	0.177	0.823	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.168	0.832	0.000
M85 Other disorders of bone density and structure	0.164	0.836	0.000
M80 Osteoporosis with pathological fracture	0.161	0.839	0.000
M84.3 Stress fracture, not elsewhere classified	0.156	0.844	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.154	0.846	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.154	0.846	0.000
M84.0 Malunion of fracture	0.149	0.851	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.149	0.851	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.148	0.852	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.148	0.852	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.148	0.852	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.147	0.853	0.000
M84.9 Disorder of continuity of bone, unspecified	0.145	0.855	0.000
M84.2 Delayed union of fracture	0.145	0.855	0.000
M84.8 Other disorders of continuity of bone	0.144	0.856	0.000
M84.4 Pathological fracture, not elsewhere classified	0.136	0.864	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.133	0.867	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.133	0.867	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.130	0.870	0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.127	0.873	0.000
M82.18 Osteoporosis in endocrine disorders (Other)	0.127	0.873	0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.127	0.873	0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.127	0.873	0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.127	0.873	0.000
M82.14 Osteoporosis in endocrine disorders (Hand)	0.127	0.873	0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.127	0.873	0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.127	0.873	0.000
M83.9 Adult osteomalacia, unspecified	0.127	0.873	0.000
M83.8 Other adult osteomalacia	0.127	0.873	0.000
M83.5 Other drug-induced osteomalacia in adults	0.127	0.873	0.000
M83.4 Aluminum bone disease	0.127	0.873	0.000
M83.3 Adult osteomalacia due to malnutrition	0.127	0.873	0.000
M83.2 Adult osteomalacia due to malabsorption	0.127	0.873	0.000
M83.1 Senile osteomalacia	0.127	0.873	0.000
M83.0 Puerperal osteomalacia	0.127	0.873	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.125	0.875	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.123	0.877	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.122	0.878	0.000
M85.8 Other specified disorders of bone density and structure	0.122	0.878	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.122	0.878	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.120	0.880	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.120	0.880	0.000
M85.9 Disorder of bone density and structure, unspecified	0.118	0.882	0.000
M85.5 Aneurysmal bone cyst	0.118	0.882	0.000
M85.4 Solitary bone cyst	0.118	0.882	0.000
M85.3 Osteitis condensans	0.118	0.882	0.000
M85.2 Hyperostosis of skull	0.118	0.882	0.000
M85.1 Skeletal fluorosis	0.118	0.882	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.117	0.882	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.116	0.884	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.116	0.884	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.116	0.884	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.116	0.884	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.112	0.888	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.112	0.888	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.112	0.888	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.112	0.888	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.112	0.888	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.112	0.888	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.112	0.888	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.112	0.888	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.112	0.888	0.000
M80.8 Other osteoporosis with pathological fracture	0.110	0.889	0.000
M84.06 Malunion of fracture (Lower leg)	0.110	0.889	0.000
M84.01 Malunion of fracture (Shoulder region)	0.110	0.890	0.000
M85.0 Fibrous dysplasia (monostotic)	0.109	0.890	0.000
M85.6 Other cyst of bone	0.108	0.892	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.107	0.893	0.000
M84.09 Malunion of fracture (Site unspecified)	0.107	0.893	0.000
M84.08 Malunion of fracture (Other)	0.107	0.893	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.107	0.893	0.000
M84.00 Malunion of fracture (Multiple sites)	0.107	0.893	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.106	0.893	0.000
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)	0.106	0.894	0.000
M82.08 Osteoporosis in multiple myelomatosis (Other)	0.106	0.894	0.000
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)	0.106	0.894	0.000
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)	0.106	0.894	0.000
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)	0.106	0.894	0.000
M82.04 Osteoporosis in multiple myelomatosis (Hand)	0.106	0.894	0.000
M82.03 Osteoporosis in multiple myelomatosis (Forearm)	0.106	0.894	0.000
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)	0.106	0.894	0.000
M82.01 Osteoporosis in multiple myelomatosis (Shoulder region)	0.106	0.894	0.000
M82.00 Osteoporosis in multiple myelomatosis (Multiple sites)	0.106	0.894	0.000
M82.89 Osteoporosis in other diseases classified elsewhere (Site unspecified)	0.106	0.894	0.000
M82.88 Osteoporosis in other diseases classified elsewhere (Other)	0.106	0.894	0.000
M82.87 Osteoporosis in other diseases classified elsewhere (Ankle and foot)	0.106	0.894	0.000
M82.86 Osteoporosis in other diseases classified elsewhere (Lower leg)	0.106	0.894	0.000
M82.85 Osteoporosis in other diseases classified elsewhere (Pelvic region and thigh)	0.106	0.894	0.000
M82.84 Osteoporosis in other diseases classified elsewhere (Hand)	0.106	0.894	0.000
M82.83 Osteoporosis in other diseases classified elsewhere (Forearm)	0.106	0.894	0.000
M82.82 Osteoporosis in other diseases classified elsewhere (Upper arm)	0.106	0.894	0.000
M82.81 Osteoporosis in other diseases classified elsewhere (Shoulder region)	0.106	0.894	0.000
M82.80 Osteoporosis in other diseases classified elsewhere (Multiple sites)	0.106	0.894	0.000
M84.04 Malunion of fracture (Hand)	0.106	0.894	0.000
M84.02 Malunion of fracture (Upper arm)	0.106	0.894	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.106	0.894	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.104	0.896	0.000
M84.28 Delayed union of fracture (Other)	0.104	0.896	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.104	0.896	0.000
M84.26 Delayed union of fracture (Lower leg)	0.104	0.896	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.104	0.896	0.000
M84.24 Delayed union of fracture (Hand)	0.104	0.896	0.000
M84.23 Delayed union of fracture (Forearm)	0.104	0.896	0.000
M84.22 Delayed union of fracture (Upper arm)	0.104	0.896	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.104	0.896	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.104	0.896	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.104	0.896	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.104	0.896	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.104	0.896	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.104	0.896	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.104	0.896	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.104	0.896	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.104	0.896	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.104	0.896	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.104	0.896	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.104	0.896	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.103	0.896	0.000
M84.88 Other disorders of continuity of bone (Other)	0.103	0.896	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.103	0.896	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.103	0.896	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.103	0.896	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.103	0.896	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.103	0.896	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.103	0.896	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.103	0.896	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.102	0.898	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.098	0.902	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.098	0.902	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.098	0.902	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.098	0.902	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.098	0.902	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.098	0.902	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.098	0.902	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.098	0.902	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.098	0.902	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.096	0.903	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.096	0.904	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.096	0.904	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.096	0.904	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.096	0.904	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.096	0.904	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.096	0.904	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.096	0.904	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.095	0.905	0.000
M83.09 Puerperal osteomalacia (Site unspecified)	0.091	0.909	0.000
M83.08 Puerperal osteomalacia (Other)	0.091	0.909	0.000
M83.07 Puerperal osteomalacia (Ankle and foot)	0.091	0.909	0.000
M83.06 Puerperal osteomalacia (Lower leg)	0.091	0.909	0.000
M83.05 Puerperal osteomalacia (Pelvic region and thigh)	0.091	0.909	0.000
M83.04 Puerperal osteomalacia (Hand)	0.091	0.909	0.000
M83.03 Puerperal osteomalacia (Forearm)	0.091	0.909	0.000
M83.02 Puerperal osteomalacia (Upper arm)	0.091	0.909	0.000
M83.01 Puerperal osteomalacia (Shoulder region)	0.091	0.909	0.000
M83.00 Puerperal osteomalacia (Multiple sites)	0.091	0.909	0.000
M83.19 Senile osteomalacia (Site unspecified)	0.091	0.909	0.000
M83.18 Senile osteomalacia (Other)	0.091	0.909	0.000
M83.17 Senile osteomalacia (Ankle and foot)	0.091	0.909	0.000
M83.16 Senile osteomalacia (Lower leg)	0.091	0.909	0.000
M83.15 Senile osteomalacia (Pelvic region and thigh)	0.091	0.909	0.000
M83.14 Senile osteomalacia (Hand)	0.091	0.909	0.000
M83.13 Senile osteomalacia (Forearm)	0.091	0.909	0.000
M83.12 Senile osteomalacia (Upper arm)	0.091	0.909	0.000
M83.11 Senile osteomalacia (Shoulder region)	0.091	0.909	0.000
M83.10 Senile osteomalacia (Multiple sites)	0.091	0.909	0.000
M83.29 Adult osteomalacia due to malabsorption (Site unspecified)	0.091	0.909	0.000
M83.28 Adult osteomalacia due to malabsorption (Other)	0.091	0.909	0.000
M83.27 Adult osteomalacia due to malabsorption (Ankle and foot)	0.091	0.909	0.000
M83.26 Adult osteomalacia due to malabsorption (Lower leg)	0.091	0.909	0.000
M83.25 Adult osteomalacia due to malabsorption (Pelvic region and thigh)	0.091	0.909	0.000
M83.24 Adult osteomalacia due to malabsorption (Hand)	0.091	0.909	0.000
M83.23 Adult osteomalacia due to malabsorption (Forearm)	0.091	0.909	0.000
M83.22 Adult osteomalacia due to malabsorption (Upper arm)	0.091	0.909	0.000
M83.21 Adult osteomalacia due to malabsorption (Shoulder region)	0.091	0.909	0.000
M83.20 Adult osteomalacia due to malabsorption (Multiple sites)	0.091	0.909	0.000
M83.39 Adult osteomalacia due to malnutrition (Site unspecified)	0.091	0.909	0.000
M83.38 Adult osteomalacia due to malnutrition (Other)	0.091	0.909	0.000
M83.37 Adult osteomalacia due to malnutrition (Ankle and foot)	0.091	0.909	0.000
M83.36 Adult osteomalacia due to malnutrition (Lower leg)	0.091	0.909	0.000
M83.35 Adult osteomalacia due to malnutrition (Pelvic region and thigh)	0.091	0.909	0.000
M83.34 Adult osteomalacia due to malnutrition (Hand)	0.091	0.909	0.000
M83.33 Adult osteomalacia due to malnutrition (Forearm)	0.091	0.909	0.000
M83.32 Adult osteomalacia due to malnutrition (Upper arm)	0.091	0.909	0.000
M83.31 Adult osteomalacia due to malnutrition (Shoulder region)	0.091	0.909	0.000
M83.30 Adult osteomalacia due to malnutrition (Multiple sites)	0.091	0.909	0.000
M83.49 Aluminium bone disease (Site unspecified)	0.091	0.909	0.000
M83.48 Aluminium bone disease (Other)	0.091	0.909	0.000
M83.47 Aluminium bone disease (Ankle and foot)	0.091	0.909	0.000
M83.46 Aluminium bone disease (Lower leg)	0.091	0.909	0.000
M83.45 Aluminium bone disease (Pelvic region and thigh)	0.091	0.909	0.000
M83.44 Aluminium bone disease (Hand)	0.091	0.909	0.000
M83.43 Aluminium bone disease (Forearm)	0.091	0.909	0.000
M83.42 Aluminium bone disease (Upper arm)	0.091	0.909	0.000
M83.41 Aluminium bone disease (Shoulder region)	0.091	0.909	0.000
M83.40 Aluminium bone disease (Multiple sites)	0.091	0.909	0.000
M83.59 Other drug-induced osteomalacia in adults (Site unspecified)	0.091	0.909	0.000
M83.58 Other drug-induced osteomalacia in adults (Other)	0.091	0.909	0.000
M83.57 Other drug-induced osteomalacia in adults (Ankle and foot)	0.091	0.909	0.000
M83.56 Other drug-induced osteomalacia in adults (Lower leg)	0.091	0.909	0.000
M83.55 Other drug-induced osteomalacia in adults (Pelvic region and thigh)	0.091	0.909	0.000
M83.54 Other drug-induced osteomalacia in adults (Hand)	0.091	0.909	0.000
M83.53 Other drug-induced osteomalacia in adults (Forearm)	0.091	0.909	0.000
M83.52 Other drug-induced osteomalacia in adults (Upper arm)	0.091	0.909	0.000
M83.51 Other drug-induced osteomalacia in adults (Shoulder region)	0.091	0.909	0.000
M83.50 Other drug-induced osteomalacia in adults (Multiple sites)	0.091	0.909	0.000
M83.89 Other adult osteomalacia (Site unspecified)	0.091	0.909	0.000
M83.88 Other adult osteomalacia (Other)	0.091	0.909	0.000
M83.87 Other adult osteomalacia (Ankle and foot)	0.091	0.909	0.000
M83.86 Other adult osteomalacia (Lower leg)	0.091	0.909	0.000
M83.85 Other adult osteomalacia (Pelvic region and thigh)	0.091	0.909	0.000
M83.84 Other adult osteomalacia (Hand)	0.091	0.909	0.000
M83.83 Other adult osteomalacia (Forearm)	0.091	0.909	0.000
M83.82 Other adult osteomalacia (Upper arm)	0.091	0.909	0.000
M83.81 Other adult osteomalacia (Shoulder region)	0.091	0.909	0.000
M83.80 Other adult osteomalacia (Multiple sites)	0.091	0.909	0.000
M83.99 Adult osteomalacia, unspecified (Site unspecified)	0.091	0.909	0.000
M83.98 Adult osteomalacia, unspecified (Other)	0.091	0.909	0.000
M83.97 Adult osteomalacia, unspecified (Ankle and foot)	0.091	0.909	0.000
M83.96 Adult osteomalacia, unspecified (Lower leg)	0.091	0.909	0.000
M83.95 Adult osteomalacia, unspecified (Pelvic region and thigh)	0.091	0.909	0.000
M83.94 Adult osteomalacia, unspecified (Hand)	0.091	0.909	0.000
M83.93 Adult osteomalacia, unspecified (Forearm)	0.091	0.909	0.000
M83.92 Adult osteomalacia, unspecified (Upper arm)	0.091	0.909	0.000
M83.91 Adult osteomalacia, unspecified (Shoulder region)	0.091	0.909	0.000
M83.90 Adult osteomalacia, unspecified (Multiple sites)	0.091	0.909	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.090	0.910	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.089	0.911	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.088	0.912	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.088	0.912	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.088	0.912	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.088	0.912	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.088	0.912	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.088	0.912	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.088	0.912	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.086	0.914	0.000
M85.64 Other cyst of bone (Hand)	0.086	0.914	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.085	0.915	0.000
M85.19 Skeletal fluorosis (Site unspecified)	0.084	0.915	0.000
M85.18 Skeletal fluorosis (Other)	0.084	0.915	0.000
M85.17 Skeletal fluorosis (Ankle and foot)	0.084	0.915	0.000
M85.16 Skeletal fluorosis (Lower leg)	0.084	0.915	0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.084	0.915	0.000
M85.14 Skeletal fluorosis (Hand)	0.084	0.915	0.000
M85.13 Skeletal fluorosis (Forearm)	0.084	0.915	0.000
M85.12 Skeletal fluorosis (Upper arm)	0.084	0.915	0.000
M85.11 Skeletal fluorosis (Shoulder region)	0.084	0.915	0.000
M85.10 Skeletal fluorosis (Multiple sites)	0.084	0.915	0.000
M85.29 Hyperostosis of skull-Site unspec	0.084	0.915	0.000
M85.28 Hyperostosis of skull-Other	0.084	0.915	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.084	0.915	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.084	0.915	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.084	0.915	0.000
M85.24 Hyperostosis of skull-Hand	0.084	0.915	0.000
M85.23 Hyperostosis of skull-Forearm	0.084	0.915	0.000
M85.22 Hyperostosis of skull-Upper arm	0.084	0.915	0.000
M85.21 Hyperostosis of skull-Shldr region	0.084	0.915	0.000
M85.20 Hyperostosis of skull-Mult sites	0.084	0.915	0.000
M85.39 Osteitis condensans (Site unspecified)	0.084	0.915	0.000
M85.38 Osteitis condensans (Other)	0.084	0.915	0.000
M85.37 Osteitis condensans (Ankle and foot)	0.084	0.915	0.000
M85.36 Osteitis condensans (Lower leg)	0.084	0.915	0.000
M85.35 Osteitis condensans (Pelvic region and thigh)	0.084	0.915	0.000
M85.34 Osteitis condensans (Hand)	0.084	0.915	0.000
M85.33 Osteitis condensans (Forearm)	0.084	0.915	0.000
M85.32 Osteitis condensans (Upper arm)	0.084	0.915	0.000
M85.31 Osteitis condensans (Shoulder region)	0.084	0.915	0.000
M85.30 Osteitis condensans (Multiple sites)	0.084	0.915	0.000
M85.49 Solitary bone cyst (Site unspecified)	0.084	0.915	0.000
M85.48 Solitary bone cyst (Other)	0.084	0.915	0.000
M85.47 Solitary bone cyst (Ankle and foot)	0.084	0.915	0.000
M85.46 Solitary bone cyst (Lower leg)	0.084	0.915	0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.084	0.915	0.000
M85.44 Solitary bone cyst (Hand)	0.084	0.915	0.000
M85.43 Solitary bone cyst (Forearm)	0.084	0.915	0.000
M85.42 Solitary bone cyst (Upper arm)	0.084	0.915	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.084	0.915	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.084	0.915	0.000
M85.59 Aneurysmal bone cyst (Site unspecified)	0.084	0.915	0.000
M85.58 Aneurysmal bone cyst (Other)	0.084	0.915	0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.084	0.915	0.000
M85.56 Aneurysmal bone cyst (Lower leg)	0.084	0.915	0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.084	0.915	0.000
M85.54 Aneurysmal bone cyst (Hand)	0.084	0.915	0.000
M85.53 Aneurysmal bone cyst (Forearm)	0.084	0.915	0.000
M85.52 Aneurysmal bone cyst (Upper arm)	0.084	0.915	0.000
M85.51 Aneurysmal bone cyst (Shoulder region)	0.084	0.915	0.000
M85.50 Aneurysmal bone cyst (Multiple sites)	0.084	0.915	0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.084	0.915	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.084	0.915	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.084	0.915	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.084	0.915	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.084	0.915	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.084	0.915	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.084	0.915	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.084	0.915	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.084	0.915	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.084	0.915	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.084	0.915	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.084	0.915	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.084	0.915	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.084	0.915	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.084	0.915	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.084	0.915	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.084	0.915	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.084	0.915	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.084	0.916	0.001
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.083	0.917	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.083	0.917	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.083	0.917	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.083	0.917	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.083	0.917	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.083	0.917	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.083	0.917	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.083	0.917	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.083	0.917	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.083	0.917	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.083	0.917	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.083	0.917	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.083	0.917	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.083	0.917	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.083	0.917	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.083	0.917	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.083	0.917	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.083	0.917	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.083	0.917	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.083	0.917	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.083	0.917	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.083	0.917	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.083	0.917	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.083	0.917	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.083	0.917	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.083	0.917	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.083	0.917	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.083	0.917	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.083	0.917	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.083	0.917	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.079	0.920	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.079	0.920	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.079	0.920	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.079	0.920	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.079	0.920	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.079	0.920	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.079	0.920	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.079	0.920	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.079	0.920	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.079	0.920	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.079	0.921	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.079	0.921	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.079	0.921	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.079	0.921	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.079	0.921	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.079	0.921	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.079	0.921	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.079	0.921	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.079	0.921	0.000
M85.69 Other cyst of bone (Site unspecified)	0.078	0.922	0.000
M85.68 Other cyst of bone (Other)	0.078	0.922	0.000
M85.66 Other cyst of bone (Lower leg)	0.078	0.922	0.000
M85.63 Other cyst of bone (Forearm)	0.078	0.922	0.000
M85.62 Other cyst of bone (Upper arm)	0.078	0.922	0.000
M85.61 Other cyst of bone (Shoulder region)	0.078	0.922	0.000
M85.60 Other cyst of bone (Multiple sites)	0.078	0.922	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.076	0.923	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.076	0.923	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.076	0.923	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.076	0.923	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.076	0.923	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.076	0.923	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.076	0.923	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.076	0.923	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.076	0.923	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.074	0.926	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.072	0.928	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.070	0.929	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.069	0.930	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.067	0.933	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.067	0.933	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.065	0.934	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.060	0.939	0.001
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.060	0.939	0.001
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.060	0.939	0.001
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.060	0.939	0.001
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.060	0.939	0.001
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.060	0.939	0.001
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.060	0.939	0.001
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.060	0.939	0.001
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.060	0.939	0.001
M84.03 Malunion of fracture (Forearm)	0.055	0.944	0.001
M24.16 Other articular cartilage disorders (Lower leg)	0.053	0.947	0.000
M24 Other specific joint derangements	0.050	0.950	0.000
M24.1 Other articular cartilage disorders	0.050	0.950	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.049	0.951	0.000
M22 Disorders of patella	0.047	0.953	0.000
M20-M25 Other joint disorders	0.047	0.953	0.000
M22.4 Chondromalacia patellae	0.045	0.955	0.000
M05-M14 Inflammatory polyarthropathies	0.045	0.955	0.000
M05 Seropositive rheumatoid arthritis	0.045	0.955	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations