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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3736757
log Bayes Factor = 2.59083
Chromosome 1   position 184,677,464  (GRCh37) Explore rs3736757 on Ensembl!
Variant rs3736757 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
J44.9 Chronic obstructive pulmonary disease, unspecified
0.988 0.012 0.000
J44 Other chronic obstructive pulmonary disease
0.987 0.013 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.931 0.069 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.929 0.071 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.921 0.079 0.000
J40-J47 Chronic lower respiratory diseases
0.852 0.148 0.000
J43 Emphysema
0.837 0.163 0.000
J43.9 Emphysema, unspecified
0.830 0.170 0.000
J45 Asthma
0.765 0.235 0.000
J46 Status asthmaticus
0.702 0.298 0.000
J45.9 Asthma, unspecified
0.682 0.318 0.000
J45.1 Nonallergic asthma
0.673 0.327 0.000
J41 Simple and mucopurulent chronic bronchitis
0.662 0.338 0.000
J43.1 Panlobular emphysema
0.600 0.400 0.000
J43.0 MacLeod's syndrome
0.600 0.400 0.000
J45.8 Mixed asthma
0.589 0.411 0.000
J42 Unspecified chronic bronchitis
0.566 0.434 0.000
J43.8 Other emphysema
0.546 0.454 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.539 0.461 0.000
J43.2 Centrilobular emphysema
0.539 0.461 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.529 0.471 0.000
M50 Cervical disk disorders
0.528 0.472 0.000
J41.0 Simple chronic bronchitis
0.525 0.475 0.000
M50.3 Other cervical disk degeneration
0.520 0.480 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.518 0.482 0.000
M54.1 Radiculopathy
0.510 0.490 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.506 0.494 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.506 0.494 0.000
M50-M54 Other dorsopathies
0.505 0.495 0.000
M54.12 Radiculopathy (Cervical region)
0.503 0.497 0.000
M54 Dorsalgia
0.500 0.500 0.000
M50.0 Cervical disk disorder with myelopathy
0.499 0.501 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.499 0.501 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.499 0.501 0.000
M54.19 Radiculopathy (Site unspecified)
0.498 0.502 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.480 0.520 0.000
M50.2 Other cervical disk displacement
0.479 0.521 0.000
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.474 0.525 0.000
J41.1 Mucopurulent chronic bronchitis
0.474 0.525 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.464 0.536 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.458 0.542 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.453 0.547 0.000
M50.9 Cervical disk disorder, unspecified
0.452 0.548 0.000
T39.0 Salicylates
0.446 0.554 0.000
T36 Poisoning by systemic antibiotics
0.443 0.557 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.436 0.564 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.424 0.576 0.000
M54.2 Cervicalgia
0.415 0.585 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.415 0.585 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.413 0.587 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.413 0.587 0.000
T40.6 Other and unspecified narcotics
0.408 0.592 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.407 0.593 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.403 0.597 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.403 0.597 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.401 0.599 0.000
M54.29 Cervicalgia-Site unspe
0.399 0.601 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.396 0.604 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.394 0.606 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.388 0.612 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.387 0.613 0.000
T50.1 Loop [high-ceiling] diuretics
0.384 0.616 0.000
T46.1 Calcium-channel blockers
0.384 0.616 0.000
T50.8 Diagnostic agents
0.382 0.617 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.381 0.618 0.000
T43.9 Psychotropic drug, unspecified
0.379 0.621 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.379 0.621 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.376 0.624 0.000
M54.6 Pain in thoracic spine
0.375 0.625 0.000
T43.6 Psychostimulants with abuse potential
0.373 0.627 0.000
T39.4 Antirheumatics, not elsewhere classified
0.371 0.629 0.000
T39.2 Pyrazolone derivatives
0.371 0.629 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.370 0.630 0.000
T40.2 Other opioids
0.369 0.631 0.000
T50.4 Drugs affecting uric acid metabolism
0.369 0.631 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.368 0.632 0.000
M80-M85 Disorders of bone density and structure
0.366 0.634 0.000
M54.15 Radiculopathy (Thoracolumbar region)
0.366 0.634 0.000
M54.13 Radiculopathy (Cervicothoracic region)
0.366 0.634 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.366 0.634 0.000
M81 Osteoporosis without pathological fracture
0.364 0.636 0.000
T45.0 Antiallergic and antiemetic drugs
0.364 0.636 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.364 0.636 0.000
M54.5 Low back pain
0.364 0.636 0.000
T36.4 Tetracyclines
0.363 0.637 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.363 0.637 0.000
T46.7 Peripheral vasodilators
0.363 0.637 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.363 0.637 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.363 0.637 0.000
M81.9 Osteoporosis, unspecified
0.361 0.639 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.361 0.639 0.000
M50.8 Other cervical disk disorders
0.360 0.640 0.000
M54.0 Panniculitis affecting regions of neck and back
0.359 0.641 0.000
T40.3 Methadone
0.358 0.642 0.000
T50.7 Analeptics and opioid receptor antagonists
0.357 0.642 0.000
T50.5 Appetite depressants
0.357 0.642 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.357 0.642 0.000
T50.0 Mineralocorticoids and their antagonists
0.357 0.642 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.356 0.644 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.354 0.646 0.000
T38.1 Thyroid hormones and substitutes
0.354 0.646 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.354 0.646 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.350 0.650 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.349 0.651 0.000
M54.59 Low back pain (Site unspecified)
0.348 0.652 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.343 0.657 0.000
M20-M25 Other joint disorders
0.342 0.658 0.000
M50.1 Cervical disk disorder with radiculopathy
0.341 0.659 0.000
M81.98 Osteoporosis, unspecified (Other)
0.340 0.660 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.340 0.660 0.000
T42.0 Hydantoin derivatives
0.337 0.663 0.000
T36.0 Penicillins
0.336 0.664 0.000
M54.14 Radiculopathy (Thoracic region)
0.333 0.667 0.000
M23 Internal derangement of knee
0.333 0.667 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.332 0.667 0.000
T40.8 Lysergide [LSD]
0.332 0.667 0.000
T40.7 Cannabis (derivatives)
0.332 0.667 0.000
T40.0 Opium
0.332 0.667 0.000
T43.2 Other and unspecified antidepressants
0.332 0.668 0.000
M54.16 Radiculopathy (Lumbar region)
0.331 0.669 0.000
M33 Dermatopolymyositis
0.326 0.674 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.325 0.675 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.325 0.675 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.325 0.675 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.325 0.675 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.325 0.675 0.000
T44.0 Anticholinesterase agents
0.325 0.675 0.000
M54.4 Lumbago with sciatica
0.325 0.675 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.322 0.678 0.000
T36.9 Systemic antibiotic, unspecified
0.318 0.682 0.000
T36.8 Other systemic antibiotics
0.318 0.682 0.000
T36.7 Antifungal antibiotics, systemically used
0.318 0.682 0.000
T36.6 Rifamycins
0.318 0.682 0.000
T36.5 Aminoglycosides
0.318 0.682 0.000
T36.3 Macrolides
0.318 0.682 0.000
T36.2 Chloramphenicol group
0.318 0.682 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.318 0.682 0.000
T40.4 Other synthetic narcotics
0.317 0.683 0.000
M80 Osteoporosis with pathological fracture
0.317 0.683 0.000
M30 Polyarteritis nodosa and related conditions
0.315 0.685 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.312 0.688 0.000
M23.4 Loose body in knee
0.312 0.688 0.000
T42.1 Iminostilbenes
0.308 0.692 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.307 0.693 0.000
M40-M43 Deforming dorsopathies
0.306 0.694 0.000
T45.2 Vitamins, not elsewhere classified
0.306 0.694 0.000
M91-M94 Chondropathies
0.305 0.695 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.304 0.696 0.000
M05-M14 Inflammatory polyarthropathies
0.304 0.696 0.000
M33.1 Other dermatomyositis
0.303 0.697 0.000
T40.1 Heroin
0.303 0.697 0.000
M85 Other disorders of bone density and structure
0.303 0.697 0.000
M51 Other intervertebral disk disorders
0.302 0.698 0.000
T40.5 Cocaine
0.302 0.698 0.000
M35 Other systemic involvement of connective tissue
0.301 0.699 0.000
M23.5 Chronic instability of knee
0.301 0.699 0.000
T38.0 Glucocorticoids and synthetic analogues
0.300 0.700 0.000
M54.27 Cervicalgia-Lumbosacral
0.298 0.702 0.000
M54.26 Cervicalgia-Lumbar
0.298 0.702 0.000
M54.25 Cervicalgia-Thoracolumbar
0.298 0.702 0.000
M54.24 Cervicalgia-Thoracic
0.298 0.702 0.000
M54.20 Cervicalgia-Mult site
0.298 0.702 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.297 0.703 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.297 0.703 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.297 0.703 0.000
M22 Disorders of patella
0.296 0.704 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.296 0.704 0.000
J45.0 Predominantly allergic asthma
0.296 0.704 0.000
M00-M03 Infectious arthropathies
0.295 0.705 0.000
M30.0 Polyarteritis nodosa
0.295 0.705 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.294 0.706 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.294 0.706 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.294 0.706 0.000
M35.0 Sicca syndrome [Sjogren]
0.294 0.706 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.292 0.708 0.000
T37.5 Antiviral drugs
0.292 0.708 0.000
T37.4 Anthelminthics
0.292 0.708 0.000
T37.3 Other antiprotozoal drugs
0.292 0.708 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.292 0.708 0.000
T37.1 Antimycobacterial drugs
0.292 0.708 0.000
T37.0 Sulphonamides
0.292 0.708 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.291 0.709 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.290 0.709 0.000
T38.9 Other and unspecified hormone antagonists
0.289 0.711 0.000
T38.7 Androgens and anabolic congeners
0.289 0.711 0.000
T38.5 Other oestrogens and progestogens
0.289 0.711 0.000
T38.4 Oral contraceptives
0.289 0.711 0.000
T38.2 Antithyroid drugs
0.289 0.711 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.287 0.712 0.000
T45.8 Other primarily systemic and haematological agents
0.287 0.712 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.287 0.712 0.000
T45.6 Fibrinolysis-affecting drugs
0.287 0.712 0.000
T45.4 Iron and its compounds
0.287 0.712 0.000
T45.3 Enzymes, not elsewhere classified
0.287 0.712 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.286 0.713 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.285 0.715 0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.284 0.716 0.000
T48.4 Expectorants
0.284 0.716 0.000
T48.3 Antitussives
0.284 0.716 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.284 0.716 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.284 0.716 0.000
T48.0 Oxytocic drugs
0.284 0.716 0.000
M81.8 Other osteoporosis
0.283 0.717 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.282 0.718 0.000
T42.2 Succinimides and oxazolidinediones
0.282 0.718 0.000
M23.49 Loose body in knee-Unspec lig/men
0.282 0.718 0.000
M86-M90 Other osteopathies
0.282 0.718 0.000
M60-M63 Disorders of muscles
0.281 0.719 0.000
M81.2 Osteoporosis of disuse
0.281 0.719 0.000
T42.3 Barbiturates
0.281 0.719 0.000
M54.50 Low back pain (Multiple sites in spine)
0.280 0.720 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.280 0.720 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.280 0.720 0.000
T41.5 Therapeutic gases
0.277 0.723 0.000
T41.4 Anaesthetic, unspecified
0.277 0.723 0.000
T41.3 Local anaesthetics
0.277 0.723 0.000
T41.2 Other and unspecified general anaesthetics
0.277 0.723 0.000
T41.1 Intravenous anaesthetics
0.277 0.723 0.000
T41.0 Inhaled anaesthetics
0.277 0.723 0.000
M81.1 Postoophorectomy osteoporosis
0.276 0.724 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.276 0.724 0.000
M54.8 Other dorsalgia
0.276 0.724 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.273 0.727 0.000
M23.9 Internal derangement of knee, unspecified
0.271 0.728 0.000
T48.5 Anti-common-cold drugs
0.271 0.729 0.000
M54.56 Low back pain (Lumbar region)
0.271 0.729 0.000
M43 Other deforming dorsopathies
0.271 0.729 0.000
M87 Osteonecrosis
0.270 0.730 0.000
M23.1 Discoid meniscus (congenital)
0.270 0.730 0.000
M54.69 Pain in thoracic spine-Site unspe
0.269 0.731 0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ
0.269 0.731 0.000
M54.67 Pain in thoracic spine-Lumbosacral
0.269 0.731 0.000
M54.66 Pain in thoracic spine-Lumbar
0.269 0.731 0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)
0.269 0.731 0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)
0.269 0.731 0.000
M54.62 Pain in thoracic spine-Cervical
0.269 0.731 0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl
0.269 0.731 0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)
0.269 0.731 0.000
M54.3 Sciatica
0.269 0.731 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.267 0.732 0.000
M83 Adult osteomalacia
0.267 0.733 0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.267 0.733 0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.266 0.734 0.000
M05 Seropositive rheumatoid arthritis
0.266 0.734 0.000
M43.0 Spondylolysis
0.264 0.736 0.000
M81.4 Drug-induced osteoporosis
0.264 0.736 0.000
M22.2 Patellofemoral disorders
0.263 0.737 0.000
M81.6 Localised osteoporosis [Lequesne]
0.261 0.739 0.000
M81.5 Idiopathic osteoporosis
0.261 0.739 0.000
M43.02 Spondylolysis (Cervical region)
0.261 0.739 0.000
M23.46 Loose body in knee-O/unsp lat men
0.261 0.739 0.000
T49.9 Topical agent, unspecified
0.261 0.739 0.000
T49.8 Other topical agents
0.261 0.739 0.000
T49.7 Dental drugs, topically applied
0.261 0.739 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.261 0.739 0.000
T49.5 Ophthalmological drugs and preparations
0.261 0.739 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.261 0.739 0.000
T49.3 Emollients, demulcents and protectants
0.261 0.739 0.000
T49.2 Local astringents and local detergents
0.261 0.739 0.000
T49.1 Antipruritics
0.261 0.739 0.000
M54.53 Low back pain-Cervicothoracic
0.261 0.739 0.000
M54.52 Low back pain-Cervical
0.261 0.739 0.000
M54.51 Low back pain-Occipit-atl-axl
0.261 0.739 0.000
M23.50 Chronic instability of knee (Multiple sites)
0.260 0.740 0.000
M33.9 Dermatopolymyositis, unspecified
0.260 0.740 0.000
M81.0 Postmenopausal osteoporosis
0.259 0.741 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.259 0.741 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.259 0.741 0.000
M23.8 Other internal derangements of knee
0.258 0.742 0.000
M13 Other arthritis
0.258 0.742 0.000
M33.2 Polymyositis
0.258 0.742 0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)
0.257 0.743 0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)
0.257 0.743 0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)
0.257 0.743 0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)
0.257 0.743 0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)
0.257 0.743 0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)
0.257 0.743 0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)
0.257 0.743 0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)
0.257 0.743 0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)
0.257 0.743 0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)
0.257 0.743 0.000
M85.4 Solitary bone cyst
0.257 0.743 0.000
M87.9 Osteonecrosis, unspecified
0.255 0.745 0.000
M12 Other specific arthropathies
0.253 0.747 0.000
M53 Other dorsopathies, not elsewhere classified
0.252 0.747 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.252 0.748 0.000
M22.3 Other derangements of patella
0.251 0.749 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.250 0.750 0.000
M93 Other osteochondropathies
0.250 0.750 0.000
M23.40 Loose body in knee-Mult sites
0.248 0.752 0.000
M22.0 Recurrent dislocation of patella
0.248 0.752 0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)
0.248 0.752 0.000
M85.6 Other cyst of bone
0.246 0.754 0.000
M82 Osteoporosis in diseases classified elsewhere
0.246 0.754 0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)
0.245 0.755 0.000
M08 Juvenile arthritis
0.245 0.755 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.243 0.757 0.000
M85.2 Hyperostosis of skull
0.241 0.759 0.000
M41 Scoliosis
0.240 0.760 0.000
M87.8 Other osteonecrosis
0.240 0.760 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.238 0.761 0.000
M92 Other juvenile osteochondrosis
0.238 0.762 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.238 0.762 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.237 0.763 0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)
0.236 0.764 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.236 0.764 0.000
M00 Pyogenic arthritis
0.236 0.764 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.235 0.765 0.000
M33.0 Juvenile dermatomyositis
0.234 0.766 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.233 0.767 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.233 0.767 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.233 0.767 0.000
M54.44 Lumbago with sciatica-Thoracic
0.233 0.767 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.233 0.767 0.000
M54.42 Lumbago with sciatica-Cervical
0.233 0.767 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.233 0.767 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.233 0.767 0.000
M54.55 Low back pain (Thoracolumbar region)
0.233 0.767 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.231 0.768 0.000
M23.44 Loose body in knee-Lat lig/ant men
0.231 0.768 0.000
M23.41 Loose body in knee-Ant lig/hrn men
0.231 0.769 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.231 0.769 0.000
M34 Systemic sclerosis
0.231 0.769 0.000
M80.8 Other osteoporosis with pathological fracture
0.230 0.769 0.000
M13.8 Other specified arthritis
0.230 0.770 0.000
M35.1 Other overlap syndromes
0.228 0.772 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.227 0.773 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.227 0.773 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.227 0.773 0.000
M85.67 Other cyst of bone (Ankle and foot)
0.227 0.773 0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.226 0.774 0.000
M30.2 Juvenile polyarteritis
0.226 0.774 0.000
M13.0 Polyarthritis, unspecified
0.226 0.774 0.000
M54.54 Low back pain-Thoracic
0.225 0.774 0.000
T42.4 Benzodiazepines
0.225 0.775 0.000
M30.8 Other conditions related to polyarteritis nodosa
0.225 0.775 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.225 0.775 0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)
0.225 0.775 0.000
M42 Spinal osteochondrosis
0.224 0.776 0.000
M23.47 Loose body in knee-Capsular lig
0.224 0.776 0.000
M23.45 Loose body in knee-Pst hrn lat men
0.224 0.776 0.000
M23.42 Loose body in knee-Pst lig/hrn men
0.224 0.776 0.000
M51.2 Other specified intervertebral disk displacement
0.223 0.777 0.000
M85.9 Disorder of bone density and structure, unspecified
0.223 0.777 0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.223 0.777 0.000
M35.8 Other specified systemic involvement of connective tissue
0.222 0.777 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.222 0.778 0.000
M81.20 Osteoporosis of disuse (Multiple sites)
0.221 0.779 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.220 0.779 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.220 0.779 0.000
T47.7 Emetics
0.220 0.779 0.000
T47.5 Digestants
0.220 0.779 0.000
T47.3 Saline and osmotic laxatives
0.220 0.779 0.000
T47.6 Antidiarrhoeal drugs
0.220 0.780 0.000
T47.0 Histamine H(2)-receptor antagonists
0.219 0.780 0.000
M54.37 Sciatica (Lumbosacral region)
0.219 0.781 0.000
M02 Reactive arthropathies
0.219 0.781 0.000
M32 Systemic lupus erythematosus
0.218 0.781 0.000
M81.89 Other osteoporosis (Site unspecified)
0.218 0.782 0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)
0.218 0.782 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.218 0.782 0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)
0.218 0.782 0.000
M85.5 Aneurysmal bone cyst
0.217 0.782 0.000
M85.3 Osteitis condensans
0.217 0.782 0.000
M85.1 Skeletal fluorosis
0.217 0.782 0.000
M05.2 Rheumatoid vasculitis
0.217 0.783 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.217 0.783 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.216 0.784 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.216 0.784 0.000
M35.5 Multifocal fibrosclerosis
0.216 0.784 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.216 0.784 0.000
M23.57 Chronic instability of knee (Capsular ligament)
0.216 0.784 0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)
0.216 0.784 0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)
0.216 0.784 0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.216 0.784 0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.216 0.784 0.000
M51.3 Other specified intervertebral disk degeneration
0.216 0.784 0.000
M81.49 Drug-induced osteoporosis (Site unspecified)
0.215 0.785 0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.215 0.785 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.215 0.785 0.000
M93.9 Osteochondropathy, unspecified
0.214 0.786 0.000
M62 Other disorders of muscle
0.214 0.786 0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)
0.213 0.787 0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)
0.213 0.787 0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)
0.213 0.787 0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)
0.213 0.787 0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)
0.213 0.787 0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)
0.213 0.787 0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)
0.213 0.787 0.000
M22.1 Recurrent subluxation of patella
0.213 0.787 0.000
M14 Arthropathies in other diseases classified elsewhere
0.212 0.788 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.212 0.788 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.212 0.788 0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)
0.211 0.789 0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)
0.211 0.789 0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp
0.211 0.789 0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn
0.211 0.789 0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.211 0.789 0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.211 0.789 0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.211 0.789 0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)
0.211 0.789 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.211 0.789 0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)
0.211 0.789 0.000
T45.5 Anticoagulants
0.210 0.789 0.000
M81.80 Other osteoporosis (Multiple sites)
0.210 0.790 0.000
M22.9 Disorder of patella, unspecified
0.210 0.790 0.000
M13.80 Other specified arthritis (Multiple sites)
0.210 0.790 0.000
M12.3 Palindromic rheumatism
0.209 0.790 0.000
M43.09 Spondylolysis (Site unspecified)
0.209 0.791 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.208 0.792 0.000
M05.1 Rheumatoid lung disease
0.207 0.793 0.000
M12.2 Villonodular synovitis (pigmented)
0.206 0.794 0.000
M60 Myositis
0.206 0.794 0.000
M85.0 Fibrous dysplasia (monostotic)
0.205 0.794 0.000
M13.1 Monoarthritis, not elsewhere classified
0.205 0.795 0.000
M51.8 Other specified intervertebral disk disorders
0.205 0.795 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.205 0.795 0.000
M85.47 Solitary bone cyst (Ankle and foot)
0.204 0.796 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.204 0.796 0.000
M81.88 Other osteoporosis (Other)
0.203 0.797 0.000
M81.87 Other osteoporosis (Ankle and foot)
0.203 0.797 0.000
M81.86 Other osteoporosis (Lower leg)
0.203 0.797 0.000
M81.85 Other osteoporosis (Pelvic region and thigh)
0.203 0.797 0.000
M81.84 Other osteoporosis (Hand)
0.203 0.797 0.000
M81.83 Other osteoporosis (Forearm)
0.203 0.797 0.000
M81.82 Other osteoporosis (Upper arm)
0.203 0.797 0.000
M81.81 Other osteoporosis (Shoulder region)
0.203 0.797 0.000
M11 Other crystal arthropathies
0.203 0.797 0.000
M83.1 Senile osteomalacia
0.202 0.798 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.202 0.798 0.000
M61 Calcification and ossification of muscle
0.202 0.798 0.000
M41.4 Neuromuscular scoliosis
0.202 0.798 0.000
M81.29 Osteoporosis of disuse (Site unspecified)
0.201 0.798 0.000
M81.28 Osteoporosis of disuse (Other)
0.201 0.798 0.000
M81.27 Osteoporosis of disuse (Ankle and foot)
0.201 0.798 0.000
M81.26 Osteoporosis of disuse (Lower leg)
0.201 0.798 0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)
0.201 0.798 0.000
M81.24 Osteoporosis of disuse (Hand)
0.201 0.798 0.000
M81.23 Osteoporosis of disuse (Forearm)
0.201 0.798 0.000
M81.22 Osteoporosis of disuse (Upper arm)
0.201 0.798 0.000
M81.21 Osteoporosis of disuse (Shoulder region)
0.201 0.798 0.000
M05.8 Other seropositive rheumatoid arthritis
0.201 0.799 0.000
T47.2 Stimulant laxatives
0.200 0.799 0.000
M87.0 Idiopathic aseptic necrosis of bone
0.199 0.800 0.000
M23.0 Cystic meniscus
0.199 0.801 0.000
M00.9 Pyogenic arthritis, unspecified
0.199 0.801 0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)
0.198 0.802 0.000
M81.18 Postoophorectomy osteoporosis (Other)
0.198 0.802 0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)
0.198 0.802 0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)
0.198 0.802 0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)
0.198 0.802 0.000
M81.14 Postoophorectomy osteoporosis (Hand)
0.198 0.802 0.000
M81.13 Postoophorectomy osteoporosis (Forearm)
0.198 0.802 0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)
0.198 0.802 0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)
0.198 0.802 0.000
M54.87 Other dorsalgia (Lumbosacral region)
0.198 0.802 0.000
M54.85 Other dorsalgia (Thoracolumbar region)
0.198 0.802 0.000
M54.83 Other dorsalgia (Cervicothoracic region)
0.198 0.802 0.000
M54.82 Other dorsalgia (Cervical region)
0.198 0.802 0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)
0.198 0.802 0.000
M54.57 Low back pain (Lumbosacral region)
0.198 0.802 0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)
0.197 0.803 0.000
M54.86 Other dorsalgia (Lumbar region)
0.197 0.803 0.000
M43.07 Spondylolysis (Lumbosacral region)
0.196 0.803 0.000
M91.2 Coxa plana
0.196 0.803 0.000
M08.9 Juvenile arthritis, unspecified
0.196 0.804 0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)
0.195 0.805 0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)
0.195 0.805 0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)
0.195 0.805 0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.195 0.805 0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.195 0.805 0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)
0.195 0.805 0.000
M43.5 Other recurrent vertebral subluxation
0.194 0.806 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.194 0.806 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.194 0.806 0.000
M87.3 Other secondary osteonecrosis
0.194 0.806 0.000
M87.1 Osteonecrosis due to drugs
0.194 0.806 0.000
M43.8 Other specified deforming dorsopathies
0.194 0.806 0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)
0.193 0.806 0.000
M23.17 Discoid meniscus (congenital)-Capsular lig
0.193 0.806 0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)
0.193 0.806 0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.193 0.806 0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)
0.193 0.806 0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.193 0.806 0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.193 0.806 0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)
0.193 0.806 0.000
M54.35 Sciatica (Thoracolumbar region)
0.193 0.807 0.000
M54.34 Sciatica-Thoracic
0.193 0.807 0.000
M54.33 Sciatica-Cervicothoracic
0.193 0.807 0.000
M54.32 Sciatica-Cervical
0.193 0.807 0.000
M54.31 Sciatica-Occipit-atl-axl
0.193 0.807 0.000
M43.2 Other fusion of spine
0.192 0.808 0.000
M85.20 Hyperostosis of skull-Mult sites
0.192 0.808 0.000
M83.9 Adult osteomalacia, unspecified
0.192 0.808 0.000
M83.5 Other drug-induced osteomalacia in adults
0.192 0.808 0.000
M83.4 Aluminum bone disease
0.192 0.808 0.000
M83.2 Adult osteomalacia due to malabsorption
0.192 0.808 0.000
M83.0 Puerperal osteomalacia
0.192 0.808 0.000
M83.3 Adult osteomalacia due to malnutrition
0.191 0.809 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.191 0.809 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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