TreeWAS – Variant ID: rs3739034

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H40.0 Glaucoma suspect	0.047	0.953	0.000
H40 Glaucoma	0.040	0.960	0.000
H40.2 Primary angle-closure glaucoma	0.038	0.962	0.000
E78.0 Pure hypercholesterolaemia	0.036	0.964	0.000
H40.4 Glaucoma secondary to eye inflammation	0.032	0.968	0.000
H40.1 Primary open-angle glaucoma	0.032	0.968	0.000
H40.3 Glaucoma secondary to eye trauma	0.031	0.969	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.029	0.971	0.000
H40.8 Other glaucoma	0.029	0.971	0.000
H40.6 Glaucoma secondary to drugs	0.029	0.971	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.028	0.972	0.000
I71 Aortic aneurysm and dissection	0.027	0.973	0.000
I74 Arterial embolism and thrombosis	0.027	0.973	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.027	0.973	0.000
I73 Other peripheral vascular diseases	0.026	0.974	0.000
I77 Other disorders of arteries and arterioles	0.026	0.974	0.000
I73.0 Raynaud's syndrome	0.026	0.974	0.000
D86.9 Sarcoidosis, unspecified	0.026	0.974	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.025	0.975	0.000
I72 Other aneurysm	0.024	0.976	0.000
D86 Sarcoidosis	0.023	0.977	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.023	0.977	0.000
I72.4 Aneurysm of artery of lower extremity	0.023	0.977	0.000
I77.1 Stricture of artery	0.023	0.977	0.000
I74.5 Embolism and thrombosis of iliac artery	0.022	0.978	0.000
D86.0 Sarcoidosis of lung	0.022	0.978	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.022	0.978	0.000
I74.8 Embolism and thrombosis of other arteries	0.021	0.979	0.000
I77.6 Arteritis, unspecified	0.021	0.979	0.000
I77.2 Rupture of artery	0.020	0.979	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.020	0.980	0.000
H40.5 Glaucoma secondary to other eye disorders	0.020	0.980	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.020	0.980	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.020	0.980	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.020	0.980	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.020	0.980	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.020	0.980	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.020	0.980	0.000
I77.0 Arteriovenous fistula, acquired	0.019	0.981	0.000
H40.9 Glaucoma, unspecified	0.019	0.981	0.000
D69 Purpura and other haemorrhagic conditions	0.019	0.981	0.000
I78 Diseases of capillaries	0.019	0.981	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.019	0.981	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.019	0.981	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.019	0.981	0.000
I77.5 Necrosis of artery	0.019	0.981	0.000
I77.4 Coeliac artery compression syndrome	0.019	0.981	0.000
I77.3 Arterial fibromuscular dysplasia	0.019	0.981	0.000
I73.9 Peripheral vascular disease, unspecified	0.019	0.981	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.018	0.982	0.000
I72.0 Aneurysm of carotid artery	0.018	0.982	0.000
D68 Other coagulation defects	0.018	0.982	0.000
I72.2 Aneurysm of renal artery	0.017	0.982	0.000
I72.9 Aneurysm of unspecified site	0.017	0.983	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.017	0.983	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.017	0.983	0.000
I72.1 Aneurysm of artery of upper extremity	0.017	0.983	0.000
D86.1 Sarcoidosis of lymph nodes	0.017	0.983	0.000
I73.8 Other specified peripheral vascular diseases	0.017	0.983	0.000
I77.8 Other specified disorders of arteries and arterioles	0.017	0.983	0.000
I72.8 Aneurysm of other specified arteries	0.017	0.983	0.000
D69.4 Other primary thrombocytopenia	0.017	0.983	0.000
D86.3 Sarcoidosis of skin	0.017	0.983	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.017	0.983	0.000
S22.40 Multiple fractures of ribs (closed)	0.000	0.983	0.017
H40-H42 Glaucoma	0.017	0.983	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.016	0.983	0.000
D86.8 Sarcoidosis of other and combined sites	0.016	0.984	0.000
D68.6 Other Thrombophilia	0.016	0.984	0.000
D80-D89 Certain disorders involving the immune mechanism	0.016	0.984	0.000
D68.9 Coagulation defect, unspecified	0.016	0.984	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.015	0.985	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.015	0.985	0.000
D68.0 Von Willebrand's disease	0.015	0.985	0.000
Z80.4 Family history of malignant neoplasm of genital organs	0.000	0.985	0.015
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.015	0.985	0.000
I78.8 Other diseases of capillaries	0.015	0.985	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.015	0.985	0.000
I79.1 Aortitis in diseases classified elsewhere	0.015	0.985	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.015	0.985	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.015	0.985	0.000
D68.1 Hereditary factor XI deficiency	0.015	0.985	0.000
D69.5 Secondary thrombocytopenia	0.015	0.985	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.014	0.985	0.000
D67 Hereditary factor IX deficiency	0.014	0.985	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.014	0.986	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.014	0.986	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.014	0.986	0.000
D69.8 Other specified haemorrhagic conditions	0.014	0.986	0.000
D69.2 Other nonthrombocytopenic purpura	0.014	0.986	0.000
D69.1 Qualitative platelet defects	0.014	0.986	0.000
T40.2 Other opioids	0.014	0.986	0.000
D66 Hereditary factor VIII deficiency	0.014	0.986	0.000
I71.0 Dissection of aorta [any part]	0.014	0.986	0.000
I78.9 Disease of capillaries, unspecified	0.014	0.986	0.000
I70 Atherosclerosis	0.013	0.986	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.013	0.986	0.000
T39.1 4-Aminophenol derivatives	0.013	0.987	0.000
D68.5 Primary Thrombophilia	0.013	0.987	0.000
D84 Other immunodeficiencies	0.013	0.987	0.000
D68.4 Acquired coagulation factor deficiency	0.013	0.987	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.013	0.987	0.000
D80 Immunodeficiency with predominantly antibody defects	0.013	0.987	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.012	0.988	0.000
H42 Glaucoma in diseases classified elsewhere	0.012	0.988	0.000
I72.3 Aneurysm of iliac artery	0.012	0.988	0.000
D69.0 Allergic purpura	0.012	0.988	0.000
T40.4 Other synthetic narcotics	0.012	0.988	0.000
T39.0 Salicylates	0.012	0.988	0.000
T36 Poisoning by systemic antibiotics	0.012	0.988	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.012	0.988	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.012	0.988	0.000
D69.9 Haemorrhagic condition, unspecified	0.011	0.988	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.012	0.988	0.000
D83 Common variable immunodeficiency	0.011	0.988	0.000
D82 Immunodeficiency associated with other major defects	0.011	0.988	0.000
D81 Combined immunodeficiencies	0.011	0.988	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.012	0.988	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.011	0.988	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.011	0.989	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.011	0.989	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.011	0.989	0.000
T45.0 Antiallergic and antiemetic drugs	0.011	0.989	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.011	0.989	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.011	0.989	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.011	0.989	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.011	0.989	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.011	0.989	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.011	0.989	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.011	0.989	0.000
D84.9 Immunodeficiency, unspecified	0.011	0.989	0.000
T46.1 Calcium-channel blockers	0.010	0.989	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.010	0.989	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.010	0.989	0.000
T39.4 Antirheumatics, not elsewhere classified	0.010	0.989	0.000
T39.2 Pyrazolone derivatives	0.010	0.989	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.010	0.989	0.000
T40.8 Lysergide [LSD]	0.010	0.989	0.000
T40.7 Cannabis (derivatives)	0.010	0.989	0.000
T40.5 Cocaine	0.010	0.989	0.000
T40.3 Methadone	0.010	0.989	0.000
T40.1 Heroin	0.010	0.989	0.000
T40.0 Opium	0.010	0.989	0.000
D84.1 Defects in the complement system	0.010	0.990	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.010	0.990	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.010	0.990	0.000
T46.7 Peripheral vasodilators	0.010	0.990	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.010	0.990	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.010	0.990	0.000
D68.8 Other specified coagulation defects	0.010	0.990	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.010	0.990	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.010	0.990	0.000
I70.9 Generalised and unspecified atherosclerosis	0.010	0.990	0.000
I70.8 Atherosclerosis of other arteries	0.010	0.990	0.000
C15.5 Lower third of oesophagus	0.010	0.990	0.000
I78.1 Naevus, nonneoplastic	0.010	0.990	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.010	0.990	0.000
D84.8 Other specified immunodeficiencies	0.009	0.990	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.009	0.990	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.010	0.990	0.000
T45.5 Anticoagulants	0.009	0.990	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.009	0.990	0.000
T45.8 Other primarily systemic and haematological agents	0.009	0.990	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.009	0.990	0.000
T45.6 Fibrinolysis-affecting drugs	0.009	0.990	0.000
T45.4 Iron and its compounds	0.009	0.990	0.000
T45.3 Enzymes, not elsewhere classified	0.009	0.990	0.000
T45.2 Vitamins, not elsewhere classified	0.009	0.990	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.009	0.991	0.000
T36.0 Penicillins	0.009	0.991	0.000
E78.4 Other hyperlipidaemia	0.009	0.991	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.009	0.991	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.009	0.991	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.009	0.991	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.009	0.991	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.009	0.991	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.009	0.991	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.009	0.991	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.009	0.991	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.009	0.991	0.000
T38.1 Thyroid hormones and substitutes	0.009	0.991	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.009	0.991	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.009	0.991	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.009	0.991	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.009	0.991	0.000
I70.1 Atherosclerosis of renal artery	0.009	0.991	0.000
T40.6 Other and unspecified narcotics	0.009	0.991	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.009	0.991	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.009	0.991	0.000
T36.9 Systemic antibiotic, unspecified	0.008	0.991	0.000
T36.8 Other systemic antibiotics	0.008	0.991	0.000
T36.7 Antifungal antibiotics, systemically used	0.008	0.991	0.000
T36.6 Rifamycins	0.008	0.991	0.000
T36.5 Aminoglycosides	0.008	0.991	0.000
T36.4 Tetracyclines	0.008	0.991	0.000
T36.3 Macrolides	0.008	0.991	0.000
T36.2 Chloramphenicol group	0.008	0.991	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.008	0.991	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.008	0.991	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.008	0.991	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.008	0.991	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.008	0.991	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.008	0.991	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.008	0.991	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.008	0.991	0.000
T44.0 Anticholinesterase agents	0.008	0.991	0.000
I70.0 Atherosclerosis of aorta	0.008	0.991	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.009	0.991	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.008	0.991	0.000
T37.5 Antiviral drugs	0.008	0.991	0.000
T37.4 Anthelminthics	0.008	0.991	0.000
T37.3 Other antiprotozoal drugs	0.008	0.991	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.008	0.991	0.000
T37.1 Antimycobacterial drugs	0.008	0.991	0.000
T37.0 Sulphonamides	0.008	0.991	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.008	0.991	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.008	0.991	0.000
D81.9 Combined immunodeficiency, unspecified	0.008	0.991	0.000
D81.8 Other combined immunodeficiencies	0.008	0.991	0.000
D81.7 Major histocompatibility complex class II deficiency	0.008	0.991	0.000
D81.6 Major histocompatibility complex class I deficiency	0.008	0.991	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.008	0.991	0.000
D81.4 Nezelof's syndrome	0.008	0.991	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.008	0.991	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.008	0.991	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.008	0.991	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.008	0.991	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.008	0.991	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.008	0.991	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.008	0.991	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.008	0.991	0.000
D82.2 Immunodeficiency with short-limbed stature	0.008	0.991	0.000
D82.1 Di George's syndrome	0.008	0.991	0.000
D82.0 Wiskott-Aldrich syndrome	0.008	0.991	0.000
D83.9 Common variable immunodeficiency, unspecified	0.008	0.991	0.000
D83.8 Other common variable immunodeficiencies	0.008	0.991	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.008	0.991	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.008	0.991	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.008	0.991	0.000
T42.0 Hydantoin derivatives	0.008	0.991	0.000
C15 Malignant neoplasm of oesophagus	0.008	0.992	0.000
T38.9 Other and unspecified hormone antagonists	0.008	0.992	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.008	0.992	0.000
T38.7 Androgens and anabolic congeners	0.008	0.992	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.008	0.992	0.000
T38.5 Other oestrogens and progestogens	0.008	0.992	0.000
T38.4 Oral contraceptives	0.008	0.992	0.000
T38.2 Antithyroid drugs	0.008	0.992	0.000
T38.0 Glucocorticoids and synthetic analogues	0.008	0.992	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.008	0.992	0.000
C15.9 Oesophagus, unspecified	0.008	0.992	0.000
T42.1 Iminostilbenes	0.008	0.992	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.008	0.992	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.008	0.992	0.000
T47.7 Emetics	0.008	0.992	0.000
T47.6 Antidiarrhoeal drugs	0.008	0.992	0.000
T47.5 Digestants	0.008	0.992	0.000
T47.4 Other laxatives	0.008	0.992	0.000
T47.3 Saline and osmotic laxatives	0.008	0.992	0.000
T47.2 Stimulant laxatives	0.008	0.992	0.000
T47.0 Histamine H(2)-receptor antagonists	0.008	0.992	0.000
S22.4 Multiple fractures of ribs	0.000	0.992	0.008
T41.5 Therapeutic gases	0.008	0.992	0.000
T41.4 Anaesthetic, unspecified	0.008	0.992	0.000
T41.3 Local anaesthetics	0.008	0.992	0.000
T41.2 Other and unspecified general anaesthetics	0.008	0.992	0.000
T41.1 Intravenous anaesthetics	0.008	0.992	0.000
T41.0 Inhaled anaesthetics	0.008	0.992	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.008	0.992	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.008	0.992	0.000
T48.5 Anti-common-cold drugs	0.008	0.992	0.000
T48.4 Expectorants	0.008	0.992	0.000
T48.3 Antitussives	0.008	0.992	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.008	0.992	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.008	0.992	0.000
T48.0 Oxytocic drugs	0.008	0.992	0.000
T49.9 Topical agent, unspecified	0.008	0.992	0.000
T49.8 Other topical agents	0.008	0.992	0.000
T49.7 Dental drugs, topically applied	0.008	0.992	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.008	0.992	0.000
T49.5 Ophthalmological drugs and preparations	0.008	0.992	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.008	0.992	0.000
T49.3 Emollients, demulcents and protectants	0.008	0.992	0.000
T49.2 Local astringents and local detergents	0.008	0.992	0.000
T49.1 Antipruritics	0.008	0.992	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.008	0.992	0.000
T43.9 Psychotropic drug, unspecified	0.008	0.992	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.008	0.992	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.008	0.992	0.000
T50.8 Diagnostic agents	0.008	0.992	0.000
T50.7 Analeptics and opioid receptor antagonists	0.008	0.992	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.008	0.992	0.000
T50.5 Appetite depressants	0.008	0.992	0.000
T50.4 Drugs affecting uric acid metabolism	0.008	0.992	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.008	0.992	0.000
T50.1 Loop [high-ceiling] diuretics	0.008	0.992	0.000
T50.0 Mineralocorticoids and their antagonists	0.008	0.992	0.000
N43.3 Hydrocele, unspecified	0.000	0.992	0.008
E78.9 Disorder of lipoprotein metabolism, unspecified	0.008	0.992	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.007	0.992	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.007	0.992	0.000
T43.6 Psychostimulants with abuse potential	0.007	0.993	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.007	0.993	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.007	0.993	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.007	0.993	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.007	0.993	0.000
C15.3 Upper third of oesophagus	0.007	0.993	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.007	0.993	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.007	0.993	0.000
T42.3 Barbiturates	0.007	0.993	0.000
T42.2 Succinimides and oxazolidinediones	0.007	0.993	0.000
E78.6 Lipoprotein deficiency	0.007	0.993	0.000
E78.3 Hyperchylomicronaemia	0.007	0.993	0.000
S62.61 Fracture of other finger (open)	0.007	0.993	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.007	0.993	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.007	0.993	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.007	0.993	0.000
D89.3 Immune reconstitution syndrome	0.007	0.993	0.000
D89.1 Cryoglobulinaemia	0.007	0.993	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.007	0.993	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.006	0.993	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.007	0.993	0.000
E78.1 Pure hyperglyceridaemia	0.007	0.993	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.006	0.993	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.006	0.994	0.000
S62.50 Fracture of thumb (closed)	0.006	0.994	0.000
C15.4 Middle third of oesophagus	0.006	0.994	0.000
C15.8 Overlapping lesion of oesophagus	0.006	0.994	0.000
C15.2 Abdominal part of oesophagus	0.006	0.994	0.000
C15.1 Thoracic part of oesophagus	0.006	0.994	0.000
C15.0 Cervical part of oesophagus	0.006	0.994	0.000
S22.41 Multiple fractures of ribs (open)	0.000	0.994	0.006
E78.8 Other disorders of lipoprotein metabolism	0.006	0.994	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.005	0.994	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.005	0.994	0.000
E78.2 Mixed hyperlipidaemia	0.005	0.994	0.000
D55-D59 Haemolytic anaemias	0.005	0.995	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.005	0.995	0.000
S62.5 Fracture of thumb	0.005	0.995	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.005	0.995	0.000
T42.4 Benzodiazepines	0.005	0.995	0.000
H33.2 Serous retinal detachment	0.000	0.995	0.005
R09.1 Pleurisy	0.000	0.995	0.005
D68.2 Hereditary deficiency of other clotting factors	0.004	0.995	0.001
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.000	0.995	0.005
I49.8 Other specified cardiac arrhythmias	0.000	0.995	0.005
S62.6 Fracture of other finger	0.005	0.995	0.000
H04.1 Other disorders of lachrymal gland	0.000	0.996	0.004
M54.36 Sciatica (Lumbar region)	0.000	0.996	0.004
S62.51 Fracture of thumb (open)	0.004	0.996	0.000
D57 Sickle-cell disorders	0.004	0.996	0.000
D56 Thalassaemia	0.004	0.996	0.000
D55 Anaemia due to enzyme disorders	0.004	0.996	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.996	0.004
S62 Fracture at wrist and hand level	0.004	0.996	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
D50-D53 Nutritional anaemias	0.004	0.996	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.003	0.996	0.000
D58 Other hereditary haemolytic anaemias	0.003	0.996	0.000
S81.8 Open wound of other parts of lower leg	0.000	0.996	0.004
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
N43 Hydrocele and spermatocele	0.000	0.996	0.004
T43.2 Other and unspecified antidepressants	0.003	0.996	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
D59 Acquired haemolytic anaemia	0.003	0.997	0.001
K76.0 Fatty (change of) liver, not elsewhere classified	0.003	0.997	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
S01.5 Open wound of lip and oral cavity	0.000	0.997	0.003
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.000	0.997	0.003
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
S62.1 Fracture of other carpal bone(s)	0.003	0.997	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.003	0.997	0.000
D55.8 Other anaemias due to enzyme disorders	0.003	0.997	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.003	0.997	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.003	0.997	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.003	0.997	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.003	0.997	0.000
D56.9 Thalassaemia, unspecified	0.003	0.997	0.000
D56.8 Other thalassaemias	0.003	0.997	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.003	0.997	0.000
D56.3 Thalassaemia trait	0.003	0.997	0.000
D56.2 Delta-beta thalassaemia	0.003	0.997	0.000
D56.1 Beta thalassaemia	0.003	0.997	0.000
D56.0 Alpha thalassaemia	0.003	0.997	0.000
D57.8 Other sickle-cell disorders	0.003	0.997	0.000
D57.3 Sickle-cell trait	0.003	0.997	0.000
D57.2 Double heterozygous sickling disorders	0.003	0.997	0.000
D57.1 Sickle-cell anaemia without crisis	0.003	0.997	0.000
D57.0 Sickle-cell anaemia with crisis	0.003	0.997	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.003	0.997	0.000
C43.9 Malignant melanoma of skin, unspecified	0.000	0.997	0.003
C43.6 Malignant melanoma of upper limb, including shoulder	0.000	0.997	0.003
T18.1 Foreign body in oesophagus	0.003	0.997	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
S62.4 Multiple fractures of metacarpal bones	0.003	0.997	0.000
C18.0 Caecum	0.003	0.997	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.003	0.997	0.000
Y84.8 Other medical procedures	0.000	0.997	0.003
D12.3 Transverse colon	0.003	0.997	0.000
K50.1 Crohn's disease of large intestine	0.003	0.997	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
T21 Burn and corrosion of trunk	0.003	0.997	0.000
F45.8 Other somatoform disorders	0.003	0.997	0.000
T21.0 Burn of unspecified degree of trunk	0.003	0.997	0.000
D53 Other nutritional anaemias	0.003	0.997	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.003	0.997	0.000
D58.2 Other haemoglobinopathies	0.003	0.997	0.000
D58.1 Hereditary elliptocytosis	0.003	0.997	0.000
C43 Malignant melanoma of skin	0.000	0.997	0.003
T21.2 Burn of second degree of trunk	0.003	0.997	0.000
N43.4 Spermatocele	0.000	0.997	0.003
S62.3 Fracture of other metacarpal bone	0.003	0.997	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.003	0.997	0.000
S62.2 Fracture of first metacarpal bone	0.003	0.997	0.000
N43.2 Other hydrocele	0.000	0.997	0.003
N43.1 Infected hydrocele	0.000	0.997	0.003
N43.0 Encysted hydrocele	0.000	0.997	0.003
D58.9 Hereditary haemolytic anaemia, unspecified	0.002	0.997	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.997	0.003
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.997	0.003
D58.0 Hereditary spherocytosis	0.002	0.997	0.000
D69.6 Thrombocytopenia, unspecified	0.003	0.997	0.000
S62.7 Multiple fractures of fingers	0.003	0.997	0.000
S62.10 Fracture of other carpal bone(s) (closed)	0.003	0.997	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.002	0.997	0.001
D59.8 Other acquired haemolytic anaemias	0.002	0.997	0.001
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.002	0.997	0.001
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.002	0.997	0.001
D59.4 Other nonautoimmune haemolytic anaemias	0.002	0.997	0.001
D59.3 Haemolytic-uraemic syndrome	0.002	0.997	0.001
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.002	0.997	0.001
D59.0 Drug-induced autoimmune haemolytic anaemia	0.002	0.997	0.001
T20-T25 Burns and corrosions of external body surface, specified by site	0.003	0.997	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.003	0.997	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.003	0.997	0.000
S62.11 Fracture of other carpal bone(s) (open)	0.002	0.997	0.000
S62.40 Multiple fractures of metacarpal bones (closed)	0.002	0.997	0.000
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.002	0.997	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
D52 Folate deficiency anaemia	0.002	0.997	0.000
S62.41 Multiple fractures of metacarpal bones (open)	0.002	0.997	0.000
L57.0 Actinic keratosis	0.003	0.997	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.002	0.997	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.002	0.997	0.000
J11.1 Influenza with other respiratory manifestations, virus not identified	0.003	0.997	0.000
M35.0 Sicca syndrome [Sjogren]	0.000	0.997	0.003
T21.3 Burn of third degree of trunk	0.002	0.997	0.000
T21.7 Corrosion of third degree of trunk	0.002	0.998	0.000
T21.6 Corrosion of second degree of trunk	0.002	0.998	0.000
T21.5 Corrosion of first degree of trunk	0.002	0.998	0.000
T21.4 Corrosion of unspecified degree of trunk	0.002	0.998	0.000
T21.1 Burn of first degree of trunk	0.002	0.998	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.002	0.998	0.000
D60-D64 Aplastic and other anaemias	0.002	0.998	0.000
M87.9 Osteonecrosis, unspecified	0.002	0.998	0.000
T20 Burn and corrosion of head and neck	0.002	0.998	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.002	0.998	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
D53.8 Other specified nutritional anaemias	0.002	0.998	0.000
D53.2 Scorbutic anaemia	0.002	0.998	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.002	0.998	0.000
D53.0 Protein deficiency anaemia	0.002	0.998	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
C43.8 Overlapping malignant melanoma of skin	0.000	0.998	0.002
C43.0 Malignant melanoma of lip	0.000	0.998	0.002
X67.9 Unspecified place	0.002	0.998	0.000
C43.5 Malignant melanoma of trunk	0.000	0.998	0.002
D53.9 Nutritional anaemia, unspecified	0.002	0.998	0.000
C43.4 Malignant melanoma of scalp and neck	0.000	0.998	0.002
Q38.7 Pharyngeal pouch	0.002	0.998	0.000
T25 Burn and corrosion of ankle and foot	0.002	0.998	0.000
S62.21 Fracture of first metacarpal bone (open)	0.002	0.998	0.000
S62.31 Fracture of other metacarpal bone (open)	0.002	0.998	0.000
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.002	0.998	0.000
Q61.2 Polycystic kidney, adult type	0.002	0.998	0.000
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
S62.71 Multiple fractures of fingers (open)	0.002	0.998	0.000
D23.1 Skin of eyelid, including canthus	0.002	0.998	0.000
K50.9 Crohn's disease, unspecified	0.002	0.998	0.000
T20.1 Burn of first degree of head and neck	0.002	0.998	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
D51 Vitamin B12 deficiency anaemia	0.002	0.998	0.000
Z03.9 Observation for suspected disease or condition, unspecified	0.002	0.998	0.000
T18 Foreign body in alimentary tract	0.002	0.998	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.000	0.998	0.002
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
K50 Crohn's disease [regional enteritis]	0.002	0.998	0.000
T58 Toxic effect of carbon monoxide	0.002	0.998	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.000	0.998	0.002
D52.8 Other folate deficiency anaemias	0.002	0.998	0.000
D52.1 Drug-induced folate deficiency anaemia	0.002	0.998	0.000
D52.0 Dietary folate deficiency anaemia	0.002	0.998	0.000
F22.0 Delusional disorder	0.002	0.998	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.002	0.998	0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations