TreeWAS – Variant ID: rs3739707

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H74 Other disorders of middle ear and mastoid	0.000	0.955	0.045
H74.4 Polyp of middle ear	0.000	0.957	0.043
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.958	0.042
H71 Cholesteatoma of middle ear	0.000	0.961	0.039
H65-H75 Diseases of middle ear and mastoid	0.000	0.961	0.039
H74.1 Adhesive middle ear disease	0.000	0.961	0.039
N13.4 Hydroureter	0.037	0.963	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.964	0.036
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.964	0.036
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.036	0.964	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.965	0.035
N13 Obstructive and reflux uropathy	0.035	0.965	0.000
H74.0 Tympanosclerosis	0.000	0.966	0.034
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.033	0.967	0.000
H73 Other disorders of tympanic membrane	0.000	0.968	0.032
S82.40 Fracture of fibula alone (closed)	0.032	0.968	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.031	0.969	0.000
H69 Other disorders of Eustachian tube	0.000	0.970	0.030
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.030	0.970	0.000
H65 Nonsuppurative otitis media	0.000	0.970	0.030
N13.9 Obstructive and reflux uropathy, unspecified	0.030	0.970	0.000
N86 Erosion and ectropion of cervix uteri	0.029	0.971	0.000
H66 Suppurative and unspecified otitis media	0.000	0.971	0.029
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.972	0.028
H68 Eustachian salpingitis and obstruction	0.000	0.972	0.028
H67 Otitis media in diseases classified elsewhere	0.000	0.972	0.028
N13.7 Vesicoureteral-reflux-associated uropathy	0.027	0.973	0.000
H65.3 Chronic mucoid otitis media	0.000	0.974	0.026
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.974	0.026
H66.9 Otitis media, unspecified	0.000	0.975	0.025
N13.8 Other obstructive and reflux uropathy	0.025	0.975	0.000
N13.6 Pyonephrosis	0.025	0.975	0.000
H65.0 Acute serous otitis media	0.000	0.975	0.025
H73.8 Other specified disorders of tympanic membrane	0.000	0.975	0.025
H69.9 Eustachian tube disorder, unspecified	0.000	0.975	0.025
H73.1 Chronic myringitis	0.000	0.977	0.023
H73.0 Acute myringitis	0.000	0.977	0.023
H65.4 Other chronic nonsuppurative otitis media	0.000	0.977	0.023
H70 Mastoiditis and related conditions	0.000	0.977	0.023
H66.0 Acute suppurative otitis media	0.000	0.977	0.023
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.977	0.023
H69.0 Patulous Eustachian tube	0.000	0.978	0.022
H69.8 Other specified disorders of Eustachian tube	0.000	0.978	0.022
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.979	0.021
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.980	0.020
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.980	0.020
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.980	0.020
H68.1 Obstruction of Eustachian tube	0.000	0.980	0.020
H68.0 Eustachian salpingitis	0.000	0.980	0.020
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.980	0.020
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.980	0.020
Z88.5 Personal history of allergy to narcotic agent	0.020	0.980	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.981	0.019
H66.4 Suppurative otitis media, unspecified	0.000	0.981	0.019
H65.2 Chronic serous otitis media	0.000	0.982	0.018
Y40.8 Other systemic antibiotics	0.017	0.982	0.000
H65.1 Other acute nonsuppurative otitis media	0.000	0.983	0.017
H70.8 Other mastoiditis and related conditions	0.000	0.983	0.016
H70.2 Petrositis	0.000	0.983	0.016
H70.1 Chronic mastoiditis	0.000	0.983	0.016
H70.0 Acute mastoiditis	0.000	0.983	0.016
I67.9 Cerebrovascular disease, unspecified	0.016	0.984	0.000
I67.8 Other specified cerebrovascular diseases	0.016	0.984	0.000
H72 Perforation of tympanic membrane	0.000	0.984	0.016
I67 Other cerebrovascular diseases	0.016	0.984	0.000
I67.1 Cerebral aneurysm, nonruptured	0.015	0.985	0.000
N83.1 Corpus luteum cyst	0.014	0.986	0.000
N83.0 Follicular cyst of ovary	0.014	0.986	0.000
S82.4 Fracture of fibula alone	0.013	0.987	0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.013	0.987	0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.012	0.988	0.000
H70.9 Mastoiditis, unspecified	0.000	0.988	0.011
I67.7 Cerebral arteritis, not elsewhere classified	0.011	0.988	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.011	0.988	0.000
I67.5 Moyamoya disease	0.011	0.988	0.000
I67.4 Hypertensive encephalopathy	0.011	0.988	0.000
I67.3 Progressive vascular leukoencephalopathy	0.011	0.988	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.011	0.989	0.000
H72.1 Attic perforation of tympanic membrane	0.000	0.989	0.011
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified	0.011	0.989	0.000
N10-N16 Renal tubulo-interstitial diseases	0.011	0.989	0.000
N83.6 Haematosalpinx	0.011	0.989	0.000
H72.8 Other perforations of tympanic membrane	0.000	0.989	0.010
N83.3 Acquired atrophy of ovary and Fallopian tube	0.010	0.989	0.000
H72.0 Central perforation of tympanic membrane	0.000	0.990	0.010
S82.41 Fracture of fibula alone (open)	0.010	0.990	0.000
C78.2 Secondary malignant neoplasm of pleura	0.000	0.990	0.010
N83.7 Haematoma of broad ligament	0.010	0.990	0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube	0.010	0.990	0.000
H72.2 Other marginal perforations of tympanic membrane	0.000	0.990	0.009
I67.2 Cerebral atherosclerosis	0.009	0.991	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.000	0.991	0.009
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.009	0.991	0.000
T40.2 Other opioids	0.000	0.991	0.009
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.000	0.991	0.009
N15 Other renal tubulo-interstitial diseases	0.008	0.992	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.000	0.992	0.008
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.992	0.008
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.008	0.992	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.008	0.992	0.000
L92.0 Granuloma annulare	0.000	0.992	0.008
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube	0.008	0.992	0.000
N10 Acute tubulo-interstitial nephritis	0.007	0.993	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.007	0.993	0.000
N11 Chronic tubulo-interstitial nephritis	0.007	0.993	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.007	0.993	0.000
N14.3 Nephropathy induced by heavy metals	0.007	0.993	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.007	0.993	0.000
N14.0 Analgesic nephropathy	0.007	0.993	0.000
J00 Acute nasopharyngitis [common cold]	0.007	0.993	0.000
N15.8 Other specified renal tubulo-interstitial diseases	0.006	0.994	0.000
N15.0 Balkan nephropathy	0.006	0.994	0.000
R25.2 Cramp and spasm	0.006	0.994	0.000
L92.2 Granuloma faciale [eosinophilic granuloma of skin]	0.000	0.994	0.006
L92.1 Necrobiosis lipoidica, not elsewhere classified	0.000	0.994	0.006
N15.1 Renal and perinephric abscess	0.006	0.994	0.000
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.006	0.994	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.006	0.994	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.006	0.994	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.006	0.994	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.006	0.994	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.006	0.994	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.000	0.994	0.006
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.994	0.006
I64 Stroke, not specified as haemorrhage or infarction	0.006	0.994	0.000
O46.9 Antepartum haemorrhage, unspecified	0.006	0.994	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.005	0.995	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.005	0.995	0.000
I60-I69 Cerebrovascular diseases	0.005	0.995	0.000
H66.3 Other chronic suppurative otitis media	0.001	0.995	0.004
R25.1 Tremor, unspecified	0.005	0.995	0.000
T40.4 Other synthetic narcotics	0.000	0.995	0.005
R25 Abnormal involuntary movements	0.005	0.995	0.000
N13.3 Other and unspecified hydronephrosis	0.005	0.995	0.000
N11.1 Chronic obstructive pyelonephritis	0.005	0.995	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.005	0.995	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.000	0.995	0.005
N83.2 Other and unspecified ovarian cysts	0.005	0.995	0.000
I73.9 Peripheral vascular disease, unspecified	0.005	0.995	0.000
K37 Unspecified appendicitis	0.005	0.995	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.996	0.004
T40.8 Lysergide [LSD]	0.000	0.996	0.004
T40.7 Cannabis (derivatives)	0.000	0.996	0.004
T40.5 Cocaine	0.000	0.996	0.004
T40.3 Methadone	0.000	0.996	0.004
T40.1 Heroin	0.000	0.996	0.004
T40.0 Opium	0.000	0.996	0.004
G62.9 Polyneuropathy, unspecified	0.004	0.996	0.000
F40.2 Specific (isolated) phobias	0.000	0.996	0.004
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.004	0.996	0.000
T40.6 Other and unspecified narcotics	0.000	0.996	0.004
N13.5 Kinking and stricture of ureter without hydronephrosis	0.004	0.996	0.001
Q21.1 Atrial septal defect	0.004	0.996	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.004	0.996	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.004	0.996	0.000
Q21 Congenital malformations of cardiac septa	0.004	0.996	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.004	0.996	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.004	0.996	0.000
Q24 Other congenital malformations of heart	0.004	0.996	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.000	0.996	0.004
Q21.0 Ventricular septal defect	0.004	0.996	0.000
R25.0 Abnormal head movements	0.004	0.996	0.000
R25.3 Fasciculation	0.004	0.996	0.000
I89.0 Lymphoedema, not elsewhere classified	0.004	0.996	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.004	0.996	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.004	0.996	0.000
I60 Subarachnoid haemorrhage	0.004	0.996	0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.004	0.996	0.000
I63.8 Other cerebral infarction	0.004	0.996	0.000
R19 Other symptoms and signs involving the digestive system and abdomen	0.004	0.996	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.004	0.996	0.000
G62.0 Drug-induced polyneuropathy	0.004	0.996	0.000
Q25 Congenital malformations of great arteries	0.004	0.996	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.004	0.996	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.004	0.996	0.000
N48.1 Balanoposthitis	0.004	0.996	0.000
I62 Other nontraumatic intracranial haemorrhage	0.004	0.996	0.000
I63 Cerebral infarction	0.004	0.996	0.000
G62 Other polyneuropathies	0.004	0.996	0.000
Q24.8 Other specified congenital malformations of heart	0.003	0.997	0.000
I31.9 Disease of pericardium, unspecified	0.000	0.997	0.003
Q25.4 Other congenital malformations of aorta	0.003	0.997	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.003	0.997	0.000
I61 Intracerebral haemorrhage	0.003	0.997	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.997	0.003
Q24.6 Congenital heart block	0.003	0.997	0.000
Q24.0 Dextrocardia	0.003	0.997	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.003	0.997	0.000
Q50.5 Embryonic cyst of broad ligament	0.003	0.997	0.000
S80.9 Superficial injury of lower leg, unspecified	0.000	0.997	0.003
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.003	0.997	0.000
M25.74 Osteophyte (Hand)	0.000	0.997	0.003
I65.2 Occlusion and stenosis of carotid artery	0.003	0.997	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.003	0.997	0.000
Q21.8 Other congenital malformations of cardiac septa	0.003	0.997	0.000
Q21.4 Aortopulmonary septal defect	0.003	0.997	0.000
Q21.2 Atrioventricular septal defect	0.003	0.997	0.000
Q24.5 Malformation of coronary vessels	0.003	0.997	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.003	0.997	0.000
M25.76 Osteophyte (Lower leg)	0.000	0.997	0.003
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.003	0.997	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.003	0.997	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.003	0.997	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.003	0.997	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.003	0.997	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.003	0.997	0.000
Q24.4 Congenital subaortic stenosis	0.003	0.997	0.000
Q24.3 Pulmonary infundibular stenosis	0.003	0.997	0.000
Q24.2 Cor triatriatum	0.003	0.997	0.000
Q24.1 Levocardia	0.003	0.997	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.003	0.997	0.000
I68.0 Cerebral amyloid angiopathy	0.003	0.997	0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.003	0.997	0.000
G62.1 Alcoholic polyneuropathy	0.003	0.997	0.000
Q21.3 Tetralogy of Fallot	0.003	0.997	0.000
Q25.6 Stenosis of pulmonary artery	0.003	0.997	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.003	0.997	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.003	0.997	0.000
Q27 Other congenital malformations of peripheral vascular system	0.003	0.997	0.000
Q26 Congenital malformations of great veins	0.003	0.997	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.003	0.997	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
I65.1 Occlusion and stenosis of basilar artery	0.003	0.997	0.000
N80.9 Endometriosis, unspecified	0.000	0.997	0.003
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.003	0.997	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.003	0.997	0.000
R19.2 Visible peristalsis	0.003	0.997	0.000
R19.3 Abdominal rigidity	0.003	0.997	0.000
R19.1 Abnormal bowel sounds	0.003	0.997	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.003	0.997	0.000
Q25.8 Other congenital malformations of great arteries	0.003	0.997	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.003	0.997	0.000
Q25.5 Atresia of pulmonary artery	0.003	0.997	0.000
Q25.3 Stenosis of aorta	0.003	0.997	0.000
Q25.2 Atresia of aorta	0.003	0.997	0.000
Q25.0 Patent ductus arteriosus	0.003	0.997	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.003	0.997	0.000
Q25.1 Coarctation of aorta	0.003	0.997	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.003	0.997	0.000
Q50.3 Other congenital malformations of ovary	0.003	0.997	0.000
Q50.2 Congenital torsion of ovary	0.003	0.997	0.000
Q50.1 Developmental ovarian cyst	0.003	0.997	0.000
Q50.0 Congenital absence of ovary	0.003	0.997	0.000
Q50-Q56 Congenital malformations of genital organs	0.003	0.997	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.003	0.997	0.000
D25.0 Submucous leiomyoma of uterus	0.003	0.997	0.000
I60.8 Other subarachnoid haemorrhage	0.003	0.997	0.000
I62.1 Nontraumatic extradural haemorrhage	0.003	0.997	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.003	0.997	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.003	0.997	0.000
B37.9 Candidiasis, unspecified	0.003	0.997	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.003	0.997	0.000
I46.9 Cardiac arrest, unspecified	0.003	0.997	0.000
G62.2 Polyneuropathy due to other toxic agents	0.003	0.997	0.000
Chapter VIII Diseases of the ear and mastoid process	0.000	0.997	0.003
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.003	0.997	0.000
Q27.3 Peripheral arteriovenous malformation	0.003	0.997	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.000	0.997	0.003
Q28 Other congenital malformations of circulatory system	0.003	0.997	0.000
M25.78 Osteophyte (Other)	0.000	0.997	0.003
I61.6 Intracerebral haemorrhage, multiple localised	0.003	0.997	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.003	0.997	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.002	0.997	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.002	0.997	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.002	0.997	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.002	0.997	0.000
I69 Sequelae of cerebrovascular disease	0.003	0.997	0.000
Q23 Congenital malformations of aortic and mitral valves	0.003	0.997	0.000
Q54 Hypospadias	0.003	0.997	0.000
Q54.0 Hypospadias, balanic	0.003	0.997	0.000
R19.6 Halitosis	0.002	0.997	0.000
Q96.9 Turner's syndrome, unspecified	0.003	0.997	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.003	0.997	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.003	0.997	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.002	0.997	0.000
Q96 Turner's syndrome	0.002	0.997	0.000
K91.3 Postoperative intestinal obstruction	0.000	0.997	0.003
M25.7 Osteophyte	0.000	0.997	0.003
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.003	0.997	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.002	0.997	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.002	0.997	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.002	0.997	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.002	0.997	0.000
Q20.6 Isomerism of atrial appendages	0.002	0.997	0.000
Q20.5 Discordant atrioventricular connexion	0.002	0.997	0.000
Q20.4 Double inlet ventricle	0.002	0.997	0.000
Q20.3 Discordant ventriculoarterial connexion	0.002	0.997	0.000
Q20.2 Double outlet left ventricle	0.002	0.997	0.000
Q20.1 Double outlet right ventricle	0.002	0.997	0.000
Q20.0 Common arterial trunk	0.002	0.997	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.002	0.997	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.002	0.997	0.000
Q22.6 Hypoplastic right heart syndrome	0.002	0.997	0.000
Q22.5 Ebstein's anomaly	0.002	0.997	0.000
Q22.4 Congenital tricuspid stenosis	0.002	0.997	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.002	0.997	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.002	0.997	0.000
Q22.1 Congenital pulmonary valve stenosis	0.002	0.997	0.000
Q22.0 Pulmonary valve atresia	0.002	0.997	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.002	0.997	0.000
Q26.8 Other congenital malformations of great veins	0.002	0.997	0.000
Q26.6 Portal vein-hepatic artery fistula	0.002	0.997	0.000
Q26.5 Anomalous portal venous connexion	0.002	0.997	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.002	0.997	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.002	0.997	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.002	0.997	0.000
Q26.1 Persistent left superior vena cava	0.002	0.997	0.000
Q26.0 Congenital stenosis of vena cava	0.002	0.997	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.002	0.998	0.000
Q27.4 Congenital phlebectasia	0.002	0.998	0.000
Q27.2 Other congenital malformations of renal artery	0.002	0.998	0.000
Q27.1 Congenital renal artery stenosis	0.002	0.998	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.002	0.998	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.002	0.998	0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.002	0.998	0.000
T39.1 4-Aminophenol derivatives	0.000	0.998	0.002
X41.9 Unspecified place	0.000	0.998	0.002
I61.8 Other intracerebral haemorrhage	0.002	0.998	0.000
Q98.4 Klinefelter's syndrome, unspecified	0.002	0.998	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.002	0.998	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.998	0.002
D72.8 Other specified disorders of white blood cells	0.002	0.998	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.002	0.998	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.002	0.998	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.002	0.998	0.000
M65.3 Trigger finger	0.002	0.998	0.000
Q52 Other congenital malformations of female genitalia	0.002	0.998	0.000
O46.8 Other antepartum haemorrhage	0.002	0.998	0.000
G62.8 Other specified polyneuropathies	0.002	0.998	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.002	0.998	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.002	0.998	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.002	0.998	0.000
M65.34 Trigger finger-Hand	0.002	0.998	0.000
Q51 Congenital malformations of uterus and cervix	0.002	0.998	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.002	0.998	0.000
S80 Superficial injury of lower leg	0.000	0.998	0.002
F84.5 Asperger's syndrome	0.000	0.998	0.002
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.000	0.998	0.002
G04.1 Tropical spastic paraplegia	0.000	0.998	0.002
G04.0 Acute disseminated encephalitis	0.000	0.998	0.002
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.002	0.998	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.002	0.998	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.002	0.998	0.000
Q28.3 Other malformations of cerebral vessels	0.002	0.998	0.000
Q28.1 Other malformations of precerebral vessels	0.002	0.998	0.000
H53.0 Amblyopia ex anopsia	0.000	0.998	0.002
S80.7 Multiple superficial injuries of lower leg	0.000	0.998	0.002
F40 Phobic anxiety disorders	0.000	0.998	0.002
M65 Synovitis and tenosynovitis	0.002	0.998	0.000
Q55 Other congenital malformations of male genital organs	0.002	0.998	0.000
Q90 Down's syndrome	0.002	0.998	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.002	0.998	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.002	0.998	0.000
M65.39 Trigger finger-Site unspec	0.002	0.998	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.002	0.998	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.002	0.998	0.000
Q23.4 Hypoplastic left heart syndrome	0.002	0.998	0.000
Q23.3 Congenital mitral insufficiency	0.002	0.998	0.000
Q23.2 Congenital mitral stenosis	0.002	0.998	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.002	0.998	0.000
I73 Other peripheral vascular diseases	0.002	0.998	0.000
Q54.8 Other hypospadias	0.002	0.998	0.000
Q54.4 Congenital chordee	0.002	0.998	0.000
Q54.3 Hypospadias, perineal	0.002	0.998	0.000
Q54.2 Hypospadias, penoscrotal	0.002	0.998	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.002	0.998	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.002	0.998	0.000
Q54.1 Hypospadias, penile	0.002	0.998	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.002	0.998	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.002	0.998	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.002	0.998	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.002	0.998	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.002	0.998	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.002	0.998	0.000
Q51.4 Unicornate uterus	0.002	0.998	0.000
Z92.2 Personal history of long-term (current) use of other medicaments	0.002	0.998	0.000
Q53 Undescended testicle	0.002	0.998	0.000
M25.70 Osteophyte (Multiple sites)	0.000	0.998	0.002
N48.9 Disorder of penis, unspecified	0.002	0.998	0.000
Q96.8 Other variants of Turner's syndrome	0.002	0.998	0.000
Q96.4 Mosaicism, 45,X/other cell line(s) with abnormal sex chromosome	0.002	0.998	0.000
Q96.3 Mosaicism, 45,X/46,XX or XY	0.002	0.998	0.000
Q96.2 Karyotype 46,X with abnormal sex chromosome, except iso (Xq)	0.002	0.998	0.000
Q96.1 Karyotype 46,X iso (Xq)	0.002	0.998	0.000
Q96.0 Karyotype 45,X	0.002	0.998	0.000
Y40 Systemic antibiotics	0.002	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.002	0.998	0.000
M25.79 Osteophyte (Site unspecified)	0.000	0.998	0.002
I73.8 Other specified peripheral vascular diseases	0.002	0.998	0.000
Q23.0 Congenital stenosis of aortic valve	0.002	0.998	0.000
M25.71 Osteophyte (Shoulder region)	0.000	0.998	0.002
Q98.9 Sex chromosome abnormality, male phenotype, unspecified	0.002	0.998	0.000
Q98.8 Other specified sex chromosome abnormalities, male phenotype	0.002	0.998	0.000
Q98.7 Male with sex chromosome mosaicism	0.002	0.998	0.000
Q98.6 Male with structurally abnormal sex chromosome	0.002	0.998	0.000
Q98.5 Karyotype 47,XYY	0.002	0.998	0.000
Q98.3 Other male with 46,XX karyotype	0.002	0.998	0.000
Q98.2 Klinefelter's syndrome, male with 46,XX karyotype	0.002	0.998	0.000
Q98.1 Klinefelter's syndrome, male with more than two X chromosomes	0.002	0.998	0.000
Q98.0 Klinefelter's syndrome karyotype 47,XXY	0.002	0.998	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.998	0.002
L08 Other local infections of skin and subcutaneous tissue	0.002	0.998	0.000
M79.89 Other specified soft tissue disorders (Site unspecified)	0.002	0.998	0.000
K52.1 Toxic gastro-enteritis and colitis	0.002	0.998	0.000
Q66.2 Metatarsus varus	0.002	0.998	0.000
T39.4 Antirheumatics, not elsewhere classified	0.000	0.998	0.002
T39.2 Pyrazolone derivatives	0.000	0.998	0.002
Q54.9 Hypospadias, unspecified	0.002	0.998	0.000
S80.8 Other superficial injuries of lower leg	0.000	0.998	0.002
Q37 Cleft palate with cleft lip	0.002	0.998	0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.002	0.998	0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.002	0.998	0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.002	0.998	0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.002	0.998	0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.002	0.998	0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.002	0.998	0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.002	0.998	0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.002	0.998	0.000
F40.0 Agoraphobia	0.000	0.998	0.002
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.002	0.998	0.000
L08.8 Other specified local infections of skin and subcutaneous tissue	0.002	0.998	0.000
Q56.4 Indeterminate sex, unspecified	0.002	0.998	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.002	0.998	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.002	0.998	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.002	0.998	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.002	0.998	0.000
M65.38 Trigger finger-Other	0.002	0.998	0.000
M65.37 Trigger finger-Ankle/foot	0.002	0.998	0.000
M65.36 Trigger finger-Lower leg	0.002	0.998	0.000
M65.35 Trigger finger-Pelvic/thigh	0.002	0.998	0.000
M65.33 Trigger finger-Forearm	0.002	0.998	0.000
M65.32 Trigger finger-Upper arm	0.002	0.998	0.000
M65.31 Trigger finger-Shldr region	0.002	0.998	0.000
M65.30 Trigger finger-Mult sites	0.002	0.998	0.000
C34.0 Main bronchus	0.000	0.998	0.002
Q52.9 Congenital malformation of female genitalia, unspecified	0.002	0.998	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.002	0.998	0.000
Q52.7 Other congenital malformations of vulva	0.002	0.998	0.000
Q52.6 Congenital malformation of clitoris	0.002	0.998	0.000
Q52.4 Other congenital malformations of vagina	0.002	0.998	0.000
Q52.3 Imperforate hymen	0.002	0.998	0.000
Q52.2 Congenital rectovaginal fistula	0.002	0.998	0.000
Q52.1 Doubling of vagina	0.002	0.998	0.000
Q52.0 Congenital absence of vagina	0.002	0.998	0.000
Q37.9 Unspecified cleft palate with unilateral cleft lip	0.002	0.998	0.000
Q90.9 Down's syndrome, unspecified	0.002	0.998	0.000
M25.77 Osteophyte (Ankle and foot)	0.000	0.998	0.002
A87.9 Viral meningitis, unspecified	0.000	0.998	0.002
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.000	0.998	0.002
M65.1 Other infective (teno)synovitis	0.002	0.998	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.002	0.998	0.000
Q52.5 Fusion of labia	0.002	0.998	0.000
S80.0 Contusion of knee	0.000	0.998	0.002
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.002	0.998	0.000
N48.5 Ulcer of penis	0.002	0.998	0.000
N48.2 Other inflammatory disorders of penis	0.002	0.998	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.002	0.998	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.002	0.998	0.000
Q51.6 Embryonic cyst of cervix	0.002	0.998	0.000
Q51.5 Agenesis and aplasia of cervix	0.002	0.998	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.002	0.998	0.000
Q51.0 Agenesis and aplasia of uterus	0.002	0.998	0.000
Y40.3 Macrolides	0.002	0.998	0.000
N48 Other disorders of penis	0.002	0.998	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.998	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.002	0.998	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.002	0.998	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.998	0.002
M25.73 Osteophyte (Forearm)	0.000	0.998	0.002
F40.9 Phobic anxiety disorder, unspecified	0.000	0.998	0.002
F40.1 Social phobias	0.000	0.998	0.002
M65.2 Calcific tendinitis	0.002	0.998	0.000
M65.0 Abscess of tendon sheath	0.002	0.998	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.002	0.998	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.002	0.998	0.000
Q55.5 Congenital absence and aplasia of penis	0.002	0.998	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.002	0.998	0.000
Q55.3 Atresia of vas deferens	0.002	0.998	0.000
Q55.1 Hypoplasia of testis and scrotum	0.002	0.998	0.000
Q55.0 Absence and aplasia of testis	0.002	0.998	0.000
Q90.2 Trisomy 21, translocation	0.002	0.998	0.000
Q90.1 Trisomy 21, mosaicism (mitotic nondisjunction)	0.002	0.998	0.000
Q90.0 Trisomy 21, meiotic nondisjunction	0.002	0.998	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.998	0.002
I61.5 Intracerebral haemorrhage, intraventricular	0.002	0.998	0.000
L08.0 Pyoderma	0.002	0.998	0.000
Q99.8 Other specified chromosome abnormalities	0.002	0.998	0.000
Y40.6 Rifamycins	0.002	0.998	0.000
Y40.4 Tetracyclines	0.002	0.998	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.002	0.998	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.002	0.998	0.000
M65.8 Other synovitis and tenosynovitis	0.002	0.998	0.000
Q99.9 Chromosomal abnormality, unspecified	0.002	0.998	0.000
Q99.2 Fragile X chromosome	0.002	0.998	0.000
Q99.1 46,XX true hermaphrodite	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations