TreeWAS – Variant ID: rs3743200

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.090	0.910	0.000
D68 Other coagulation defects	0.000	0.928	0.072
D68.8 Other specified coagulation defects	0.000	0.930	0.070
D68.9 Coagulation defect, unspecified	0.000	0.933	0.067
M23.8 Other internal derangements of knee	0.067	0.933	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.934	0.066
D68.0 Von Willebrand's disease	0.000	0.935	0.065
D68.6 Other Thrombophilia	0.000	0.936	0.064
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.062	0.938	0.000
D68.5 Primary Thrombophilia	0.000	0.941	0.059
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.056	0.944	0.000
D68.4 Acquired coagulation factor deficiency	0.000	0.948	0.052
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.050	0.949	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.050	0.950	0.000
D68.1 Hereditary factor XI deficiency	0.000	0.950	0.049
M23.87 Other internal derangements of knee (Capsular ligament)	0.048	0.952	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.048	0.952	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.042	0.958	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.034	0.966	0.000
D68.2 Hereditary deficiency of other clotting factors	0.000	0.966	0.034
Z95.1 Presence of aortocoronary bypass graft	0.022	0.978	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.984	0.016
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.986	0.014
H66 Suppurative and unspecified otitis media	0.011	0.989	0.000
H74 Other disorders of middle ear and mastoid	0.011	0.989	0.000
H71 Cholesteatoma of middle ear	0.011	0.989	0.000
H72 Perforation of tympanic membrane	0.010	0.990	0.000
H72.0 Central perforation of tympanic membrane	0.010	0.990	0.000
H65-H75 Diseases of middle ear and mastoid	0.010	0.990	0.000
D67 Hereditary factor IX deficiency	0.000	0.990	0.010
K04.7 Periapical abscess without sinus	0.000	0.990	0.010
H74.3 Other acquired abnormalities of ear ossicles	0.010	0.990	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.010	0.990	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.010	0.990	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.010	0.990	0.000
D66 Hereditary factor VIII deficiency	0.000	0.990	0.010
H66.3 Other chronic suppurative otitis media	0.010	0.990	0.000
H74.4 Polyp of middle ear	0.010	0.990	0.000
C49.0 Connective and soft tissue of head, face and neck	0.009	0.991	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.009	0.991	0.000
C45 Mesothelioma	0.009	0.991	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.009	0.991	0.000
F20.9 Schizophrenia, unspecified	0.000	0.991	0.009
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.009	0.991	0.000
C49.5 Connective and soft tissue of pelvis	0.009	0.991	0.000
H72.1 Attic perforation of tympanic membrane	0.009	0.991	0.000
C49.6 Connective and soft tissue of trunk, unspecified	0.009	0.991	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.009	0.991	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.991	0.009
H66.9 Otitis media, unspecified	0.008	0.992	0.000
H72.2 Other marginal perforations of tympanic membrane	0.008	0.992	0.000
H66.0 Acute suppurative otitis media	0.008	0.992	0.000
C49.1 Connective and soft tissue of upper limb, including shoulder	0.008	0.992	0.000
C45.7 Mesothelioma of other sites	0.008	0.992	0.000
H66.4 Suppurative otitis media, unspecified	0.008	0.992	0.000
C45.0 Mesothelioma of pleura	0.008	0.992	0.000
E27.8 Other specified disorders of adrenal gland	0.008	0.992	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.992	0.008
H72.8 Other perforations of tympanic membrane	0.008	0.992	0.000
C45.9 Mesothelioma, unspecified	0.008	0.992	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.008	0.992	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.008	0.992	0.000
H74.1 Adhesive middle ear disease	0.008	0.992	0.000
C49.4 Connective and soft tissue of abdomen	0.008	0.992	0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.008	0.992	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.007	0.992	0.000
H68 Eustachian salpingitis and obstruction	0.007	0.992	0.000
H67 Otitis media in diseases classified elsewhere	0.007	0.992	0.000
E27.9 Disorder of adrenal gland, unspecified	0.007	0.992	0.000
C49.8 Overlapping lesion of connective and soft tissue	0.007	0.993	0.000
Z57.2 Occupational exposure to dust	0.007	0.993	0.000
E27 Other disorders of adrenal gland	0.007	0.993	0.000
H70 Mastoiditis and related conditions	0.007	0.993	0.000
C49.9 Connective and soft tissue, unspecified	0.007	0.993	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.993	0.007
C49.3 Connective and soft tissue of thorax	0.007	0.993	0.000
C45.2 Mesothelioma of pericardium	0.007	0.993	0.000
C45.1 Mesothelioma of peritoneum	0.007	0.993	0.000
C48.1 Specified parts of peritoneum	0.007	0.993	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.993	0.007
H72.9 Perforation of tympanic membrane, unspecified	0.007	0.993	0.000
H74.0 Tympanosclerosis	0.007	0.993	0.000
C48.0 Retroperitoneum	0.007	0.993	0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.006	0.993	0.000
C46 Kaposi's sarcoma	0.006	0.993	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.994	0.006
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.994	0.006
I98.0 Cardiovascular syphilis	0.000	0.994	0.006
D63.8 Anaemia in other chronic diseases classified elsewhere	0.000	0.994	0.006
E27.1 Primary adrenocortical insufficiency	0.006	0.994	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.006	0.994	0.000
G51.0 Bell's palsy	0.000	0.994	0.006
D62 Acute posthaemorrhagic anaemia	0.000	0.994	0.006
E27.3 Drug-induced adrenocortical insufficiency	0.006	0.994	0.000
C48.8 Overlapping lesion of retroperitoneum and peritoneum	0.006	0.994	0.000
K52.1 Toxic gastro-enteritis and colitis	0.000	0.994	0.006
H67.8 Otitis media in other diseases classified elsewhere	0.005	0.994	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.005	0.994	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.005	0.994	0.000
H68.1 Obstruction of Eustachian tube	0.005	0.994	0.000
H68.0 Eustachian salpingitis	0.005	0.994	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.005	0.994	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.005	0.994	0.000
H11.9 Disorder of conjunctiva, unspecified	0.006	0.994	0.000
D22.0 Melanocytic naevi of lip	0.000	0.994	0.006
D69 Purpura and other haemorrhagic conditions	0.000	0.994	0.006
E27.5 Adrenomedullary hyperfunction	0.005	0.995	0.000
E27.0 Other adrenocortical overactivity	0.005	0.995	0.000
H70.1 Chronic mastoiditis	0.005	0.995	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.000	0.995	0.005
N13.8 Other obstructive and reflux uropathy	0.000	0.995	0.005
D60-D64 Aplastic and other anaemias	0.000	0.995	0.005
H70.2 Petrositis	0.005	0.995	0.000
H70.0 Acute mastoiditis	0.005	0.995	0.000
Z57 Occupational exposure to risk-factors	0.005	0.995	0.000
H70.8 Other mastoiditis and related conditions	0.005	0.995	0.000
J11.1 Influenza with other respiratory manifestations, virus not identified	0.005	0.995	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.005	0.995	0.000
C48.2 Peritoneum, unspecified	0.005	0.995	0.000
H69 Other disorders of Eustachian tube	0.005	0.995	0.000
C46.9 Kaposi's sarcoma, unspecified	0.005	0.995	0.000
C46.8 Kaposi's sarcoma of multiple organs	0.005	0.995	0.000
C46.7 Kaposi's sarcoma of other sites	0.005	0.995	0.000
C46.3 Kaposi's sarcoma of lymph nodes	0.005	0.995	0.000
C46.2 Kaposi's sarcoma of palate	0.005	0.995	0.000
C46.1 Kaposi's sarcoma of soft tissue	0.005	0.995	0.000
C46.0 Kaposi's sarcoma of skin	0.005	0.995	0.000
C47.9 Peripheral nerves and autonomic nervous system, unspecified	0.005	0.995	0.000
C47.8 Overlapping lesion of peripheral nerves and autonomic nervous system	0.005	0.995	0.000
C47.6 Peripheral nerves of trunk, unspecified	0.005	0.995	0.000
C47.5 Peripheral nerves of pelvis	0.005	0.995	0.000
C47.4 Peripheral nerves of abdomen	0.005	0.995	0.000
C47.3 Peripheral nerves of thorax	0.005	0.995	0.000
C47.2 Peripheral nerves of lower limb, including hip	0.005	0.995	0.000
C47.1 Peripheral nerves of upper limb, including shoulder	0.005	0.995	0.000
C47.0 Peripheral nerves of head, face and neck	0.005	0.995	0.000
Z57.3 Occupational exposure to other air contaminants	0.005	0.995	0.000
G51.9 Disorder of facial nerve, unspecified	0.000	0.995	0.005
F20 Schizophrenia	0.000	0.995	0.005
O42.9 Premature rupture of membranes, unspecified	0.005	0.995	0.000
G51 Facial nerve disorders	0.000	0.995	0.005
H70.9 Mastoiditis, unspecified	0.004	0.995	0.000
D69.4 Other primary thrombocytopenia	0.000	0.995	0.005
M23 Internal derangement of knee	0.005	0.995	0.000
D69.2 Other nonthrombocytopenic purpura	0.000	0.995	0.004
I20.0 Unstable angina	0.005	0.995	0.000
H73 Other disorders of tympanic membrane	0.004	0.995	0.000
D69.9 Haemorrhagic condition, unspecified	0.000	0.996	0.004
Z57.5 Occupational exposure to toxic agents in other industries	0.004	0.996	0.000
G51.3 Clonic hemifacial spasm	0.000	0.996	0.004
Z57.8 Occupational exposure to other risk-factors	0.004	0.996	0.000
D69.8 Other specified haemorrhagic conditions	0.000	0.996	0.004
D69.1 Qualitative platelet defects	0.000	0.996	0.004
D69.5 Secondary thrombocytopenia	0.000	0.996	0.004
E27.2 Addisonian crisis	0.004	0.996	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.996	0.004
S42.40 Fracture of lower end of humerus (closed)	0.004	0.996	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.996	0.004
H25.1 Senile nuclear cataract	0.000	0.996	0.004
D63.1 Anaemia in other chronic diseases classified elsewhere	0.000	0.996	0.004
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.000	0.996	0.004
Z57.9 Occupational exposure to unspecified risk-factor	0.004	0.996	0.000
Z57.7 Occupational exposure to vibration	0.004	0.996	0.000
Z57.6 Occupational exposure to extreme temperature	0.004	0.996	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.004	0.996	0.000
Z57.1 Occupational exposure to radiation	0.004	0.996	0.000
Z57.0 Occupational exposure to noise	0.004	0.996	0.000
D61 Other aplastic anaemias	0.000	0.996	0.004
L73.9 Follicular disorder, unspecified	0.000	0.996	0.004
F20.5 Residual schizophrenia	0.000	0.996	0.004
M19.01 Primary arthrosis of other joints (Shoulder region)	0.004	0.996	0.000
H69.0 Patulous Eustachian tube	0.004	0.996	0.000
R09.1 Pleurisy	0.004	0.996	0.000
F20.8 Other schizophrenia	0.000	0.996	0.004
F20.6 Simple schizophrenia	0.000	0.996	0.004
F20.4 Postschizophrenic depression	0.000	0.996	0.004
F20.3 Undifferentiated schizophrenia	0.000	0.996	0.004
F20.2 Catatonic schizophrenia	0.000	0.996	0.004
F20.1 Hebephrenic schizophrenia	0.000	0.996	0.004
M23.6 Other spontaneous disruption of ligament(s) of knee	0.004	0.996	0.000
M23.0 Cystic meniscus	0.004	0.996	0.000
G51.4 Facial myokymia	0.000	0.996	0.004
G51.2 Melkersson's syndrome	0.000	0.996	0.004
G51.1 Geniculate ganglionitis	0.000	0.996	0.004
K51.4 Pseudopolyposis of colon	0.000	0.996	0.004
L29.9 Pruritus, unspecified	0.000	0.996	0.004
H73.1 Chronic myringitis	0.003	0.996	0.000
H73.0 Acute myringitis	0.003	0.996	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.004	0.996	0.000
D61.9 Aplastic anaemia, unspecified	0.000	0.997	0.003
E53.8 Deficiency of other specified B group vitamins	0.000	0.997	0.003
M24.16 Other articular cartilage disorders (Lower leg)	0.003	0.997	0.000
S42.4 Fracture of lower end of humerus	0.003	0.997	0.000
M23.5 Chronic instability of knee	0.003	0.997	0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.003	0.997	0.000
M23.9 Internal derangement of knee, unspecified	0.003	0.997	0.000
M23.4 Loose body in knee	0.003	0.997	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.000	0.997	0.003
D60.8 Other acquired pure red cell aplasias	0.000	0.997	0.003
D60.1 Transient acquired pure red cell aplasia	0.000	0.997	0.003
D60.0 Chronic acquired pure red cell aplasia	0.000	0.997	0.003
K51.9 Ulcerative colitis, unspecified	0.000	0.997	0.003
D61.8 Other specified aplastic anaemias	0.000	0.997	0.003
D61.3 Idiopathic aplastic anaemia	0.000	0.997	0.003
D61.2 Aplastic anaemia due to other external agents	0.000	0.997	0.003
O42 Premature rupture of membranes	0.003	0.997	0.000
D61.1 Drug-induced aplastic anaemia	0.000	0.997	0.003
G51.8 Other disorders of facial nerve	0.000	0.997	0.003
C71.4 Occipital lobe	0.000	0.997	0.003
H69.8 Other specified disorders of Eustachian tube	0.003	0.997	0.000
F20.0 Paranoid schizophrenia	0.000	0.997	0.003
M23.1 Discoid meniscus (congenital)	0.003	0.997	0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.003	0.997	0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997	0.000
C71.2 Temporal lobe	0.000	0.997	0.003
E34.9 Endocrine disorder, unspecified	0.003	0.997	0.000
D64 Other anaemias	0.000	0.997	0.003
C71 Malignant neoplasm of brain	0.000	0.997	0.003
E23.7 Disorder of pituitary gland, unspecified	0.003	0.997	0.000
D50-D53 Nutritional anaemias	0.000	0.997	0.003
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
L73.2 Hidradenitis suppurativa	0.000	0.997	0.003
S42.41 Fracture of lower end of humerus (open)	0.003	0.997	0.000
E34.8 Other specified endocrine disorders	0.003	0.997	0.000
M23.07 Cystic meniscus-Capsular lig	0.003	0.997	0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.003	0.997	0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.003	0.997	0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997	0.000
M23.00 Cystic meniscus (Multiple sites)	0.003	0.997	0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.003	0.997	0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.003	0.997	0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.003	0.997	0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.003	0.997	0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.003	0.997	0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.003	0.997	0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.003	0.997	0.000
C71.8 Overlapping lesion of brain	0.000	0.997	0.003
D61.0 Constitutional aplastic anaemia	0.000	0.997	0.003
E34 Other endocrine disorders	0.003	0.997	0.000
D69.0 Allergic purpura	0.000	0.997	0.003
H20.9 Iridocyclitis, unspecified	0.000	0.997	0.003
C71.3 Parietal lobe	0.000	0.997	0.003
K51 Ulcerative colitis	0.000	0.997	0.003
D51 Vitamin B12 deficiency anaemia	0.000	0.997	0.003
L73 Other follicular disorders	0.000	0.997	0.003
D64.8 Other specified anaemias	0.000	0.997	0.003
E23 Hypofunction and other disorders of pituitary gland	0.003	0.997	0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.003	0.997	0.000
H69.9 Eustachian tube disorder, unspecified	0.003	0.997	0.000
D52 Folate deficiency anaemia	0.000	0.997	0.003
C50.5 Lower-outer quadrant of breast	0.000	0.997	0.003
H73.9 Disorder of tympanic membrane, unspecified	0.002	0.997	0.000
S00.1 Contusion of eyelid and periocular area	0.000	0.997	0.003
S42.00 Fracture of clavicle (closed)	0.003	0.997	0.000
C71.9 Brain, unspecified	0.000	0.997	0.003
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.003	0.997	0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997	0.000
D63.0 Anaemia in neoplastic disease	0.000	0.997	0.003
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.003	0.997	0.000
D52.9 Folate deficiency anaemia, unspecified	0.000	0.997	0.003
G82.2 Paraplegia, unspecified	0.000	0.997	0.003
M23.57 Chronic instability of knee (Capsular ligament)	0.002	0.997	0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.002	0.997	0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.002	0.997	0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.997	0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.997	0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.997	0.000
M23.50 Chronic instability of knee (Multiple sites)	0.002	0.997	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.997	0.003
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.002	0.997	0.000
E23.2 Diabetes insipidus	0.003	0.997	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.997	0.003
K51.2 Ulcerative (chronic) proctitis	0.000	0.997	0.003
M23.47 Loose body in knee-Capsular lig	0.002	0.997	0.000
M23.45 Loose body in knee-Pst hrn lat men	0.002	0.997	0.000
M23.44 Loose body in knee-Lat lig/ant men	0.002	0.997	0.000
M23.42 Loose body in knee-Pst lig/hrn men	0.002	0.997	0.000
M23.41 Loose body in knee-Ant lig/hrn men	0.002	0.997	0.000
M23.40 Loose body in knee-Mult sites	0.002	0.997	0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.002	0.997	0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.002	0.997	0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.002	0.997	0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.997	0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.997	0.000
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.997	0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.002	0.997	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.997	0.003
E23.6 Other disorders of pituitary gland	0.003	0.997	0.000
Z99.8 Dependence on other enabling machines and devices	0.003	0.997	0.000
E20-E35 Disorders of other endocrine glands	0.003	0.997	0.000
M23.43 Loose body in knee-Med lig/oth men	0.002	0.997	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.997	0.003
O42.2 Premature rupture of membranes, labour delayed by therapy	0.002	0.997	0.000
Z95.4 Presence of other heart-valve replacement	0.003	0.997	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.003	0.997	0.000
M23.3 Other meniscus derangements	0.003	0.997	0.000
D55-D59 Haemolytic anaemias	0.000	0.997	0.002
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
M23.17 Discoid meniscus (congenital)-Capsular lig	0.002	0.998	0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.002	0.998	0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.002	0.998	0.000
M23.49 Loose body in knee-Unspec lig/men	0.002	0.998	0.000
S42.0 Fracture of clavicle	0.002	0.998	0.000
R34 Anuria and oliguria	0.002	0.998	0.000
M23.46 Loose body in knee-O/unsp lat men	0.002	0.998	0.000
C71.7 Brain stem	0.000	0.998	0.002
C71.6 Cerebellum	0.000	0.998	0.002
C71.0 Cerebrum, except lobes and ventricles	0.000	0.998	0.002
D64.4 Congenital dyserythropoietic anaemia	0.000	0.998	0.002
D64.3 Other sideroblastic anaemias	0.000	0.998	0.002
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.000	0.998	0.002
D64.1 Secondary sideroblastic anaemia due to disease	0.000	0.998	0.002
D64.0 Hereditary sideroblastic anaemia	0.000	0.998	0.002
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.000	0.998	0.002
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.998	0.002
E34.5 Androgen resistance syndrome	0.002	0.998	0.000
E34.4 Constitutional tall stature	0.002	0.998	0.000
E34.3 Short stature, not elsewhere classified	0.002	0.998	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.002	0.998	0.000
E34.1 Other hypersecretion of intestinal hormones	0.002	0.998	0.000
L73.8 Other specified follicular disorders	0.000	0.998	0.002
O32.9 Maternal care for malpresentation of foetus, unspecified	0.002	0.998	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
L73.1 Pseudofolliculitis barbae	0.000	0.998	0.002
L73.0 Acne keloid	0.000	0.998	0.002
S42.30 Fracture of shaft of humerus (closed)	0.002	0.998	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.998	0.002
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.998	0.002
D51.2 Transcobalamin II deficiency	0.000	0.998	0.002
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.998	0.002
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.002	0.998	0.000
K52 Other non-infective gastro-enteritis and colitis	0.000	0.998	0.002
D53 Other nutritional anaemias	0.000	0.998	0.002
H10 Conjunctivitis	0.002	0.998	0.000
D52.8 Other folate deficiency anaemias	0.000	0.998	0.002
D52.1 Drug-induced folate deficiency anaemia	0.000	0.998	0.002
D52.0 Dietary folate deficiency anaemia	0.000	0.998	0.002
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.002	0.998	0.000
E23.1 Drug-induced hypopituitarism	0.002	0.998	0.000
T42.0 Hydantoin derivatives	0.002	0.998	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
H10.9 Conjunctivitis, unspecified	0.002	0.998	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.998	0.002
S42 Fracture of shoulder and upper arm	0.002	0.998	0.000
H91.9 Hearing loss, unspecified	0.002	0.998	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.002	0.998	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.002	0.998	0.000
K51.8 Other ulcerative colitis	0.000	0.998	0.002
S42.3 Fracture of shaft of humerus	0.002	0.998	0.000
H10.4 Chronic conjunctivitis	0.002	0.998	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.002	0.998	0.000
T42.3 Barbiturates	0.002	0.998	0.000
T42.2 Succinimides and oxazolidinediones	0.002	0.998	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.000	0.998	0.002
C71.5 Cerebral ventricle	0.000	0.998	0.002
R16.0 Hepatomegaly, not elsewhere classified	0.000	0.998	0.002
E25 Adrenogenital disorders	0.002	0.998	0.000
H10.0 Mucopurulent conjunctivitis	0.002	0.998	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.002	0.998	0.000
E32 Diseases of thymus	0.002	0.998	0.000
E31 Polyglandular dysfunction	0.002	0.998	0.000
E30 Disorders of puberty, not elsewhere classified	0.002	0.998	0.000
S00.8 Superficial injury of other parts of head	0.000	0.998	0.002
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.998	0.002
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.000	0.998	0.002
T42.1 Iminostilbenes	0.002	0.998	0.000
Z95.2 Presence of prosthetic heart valve	0.002	0.998	0.000
C71.1 Frontal lobe	0.000	0.998	0.002
K76.6 Portal hypertension	0.000	0.998	0.002
N99.4 Postprocedural pelvic peritoneal adhesions	0.002	0.998	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.000	0.998	0.002
S42.1 Fracture of scapula	0.002	0.998	0.000
J11 Influenza, virus not identified	0.002	0.998	0.000
M23.37 Other meniscus derangements-Capsular lig	0.002	0.998	0.000
O32.8 Maternal care for other malpresentation of foetus	0.002	0.998	0.000
D57 Sickle-cell disorders	0.000	0.998	0.002
D55 Anaemia due to enzyme disorders	0.000	0.998	0.002
S42.01 Fracture of clavicle (open)	0.002	0.998	0.000
H73.8 Other specified disorders of tympanic membrane	0.002	0.998	0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.000	0.998	0.002
E24 Cushing's syndrome	0.002	0.998	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.000	0.998	0.002
Chapter VIII Diseases of the ear and mastoid process	0.002	0.998	0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
H10.3 Acute conjunctivitis, unspecified	0.002	0.998	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.002	0.998	0.000
Z95.3 Presence of xenogenic heart valve	0.002	0.998	0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.002	0.998	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.002	0.998	0.000
E53 Deficiency of other B group vitamins	0.000	0.998	0.002
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.998	0.002
E26 Hyperaldosteronism	0.002	0.998	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.002	0.998	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.002	0.998	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.000	0.998	0.002
E20 Hypoparathyroidism	0.002	0.998	0.000
H20 Iridocyclitis	0.000	0.998	0.002
S42.10 Fracture of scapula (closed)	0.002	0.998	0.000
E24.2 Drug-induced Cushing's syndrome	0.002	0.998	0.000
E34.0 Carcinoid syndrome	0.002	0.998	0.000
D59 Acquired haemolytic anaemia	0.000	0.998	0.002
D56 Thalassaemia	0.000	0.998	0.002
D53.8 Other specified nutritional anaemias	0.000	0.998	0.002
D53.2 Scorbutic anaemia	0.000	0.998	0.002
D53.0 Protein deficiency anaemia	0.000	0.998	0.002
H10.8 Other conjunctivitis	0.002	0.998	0.000
H10.5 Blepharoconjunctivitis	0.002	0.998	0.000
H10.2 Other acute conjunctivitis	0.002	0.998	0.000
H10.1 Acute atopic conjunctivitis	0.002	0.998	0.000
H11 Other disorders of conjunctiva	0.002	0.998	0.000
D80-D89 Certain disorders involving the immune mechanism	0.000	0.998	0.002
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
D53.9 Nutritional anaemia, unspecified	0.000	0.998	0.002
S93.1 Dislocation of toe(s)	0.000	0.998	0.002
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.998	0.002
H20.0 Acute and subacute iridocyclitis	0.000	0.998	0.002
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.000	0.998	0.002
S00.5 Superficial injury of lip and oral cavity	0.000	0.998	0.002
E28 Ovarian dysfunction	0.002	0.998	0.000
K50-K52 Noninfective enteritis and colitis	0.000	0.998	0.002
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.002	0.998	0.000
E28.3 Primary ovarian failure	0.002	0.998	0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.000	0.998	0.002
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
H11.2 Conjunctival scars	0.002	0.998	0.000
E25.9 Adrenogenital disorder, unspecified	0.002	0.998	0.000
E25.8 Other adrenogenital disorders	0.002	0.998	0.000
M89.9 Disorder of bone, unspecified	0.000	0.998	0.002
O32.0 Maternal care for unstable lie	0.002	0.998	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.002	0.998	0.000
T46.1 Calcium-channel blockers	0.002	0.998	0.000
S42.31 Fracture of shaft of humerus (open)	0.002	0.998	0.000
D72.1 Eosinophilia	0.000	0.998	0.002
S42.8 Fracture of other parts of shoulder and upper arm	0.002	0.998	0.000
E29 Testicular dysfunction	0.002	0.998	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.998	0.002
E30.9 Disorder of puberty, unspecified	0.002	0.998	0.000
E30.8 Other disorders of puberty	0.002	0.998	0.000
E30.1 Precocious puberty	0.002	0.998	0.000
E30.0 Delayed puberty	0.002	0.998	0.000
E31.9 Polyglandular dysfunction, unspecified	0.002	0.998	0.000
E31.8 Other polyglandular dysfunction	0.002	0.998	0.000
E31.1 Polyglandular hyperfunction	0.002	0.998	0.000
E31.0 Autoimmune polyglandular failure	0.002	0.998	0.000
E32.9 Disease of thymus, unspecified	0.002	0.998	0.000
E32.8 Other diseases of thymus	0.002	0.998	0.000
E32.1 Abscess of thymus	0.002	0.998	0.000
E32.0 Persistent hyperplasia of thymus	0.002	0.998	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.002	0.998	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.002	0.998	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.002	0.998	0.000
K65.9 Peritonitis, unspecified	0.000	0.998	0.002
O32.1 Maternal care for breech presentation	0.002	0.998	0.000
F29 Unspecified nonorganic psychosis	0.000	0.998	0.002
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.000	0.998	0.002
H18.2 Other corneal oedema	0.000	0.998	0.002
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
T47.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
S42.11 Fracture of scapula (open)	0.002	0.998	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.002	0.998	0.000
J11.8 Influenza with other manifestations, virus not identified	0.002	0.998	0.000
W19.2 School, other institution and public administrative area	0.000	0.998	0.002
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.000	0.998	0.001
D55.8 Other anaemias due to enzyme disorders	0.000	0.998	0.001
D55.3 Anaemia due to disorders of nucleotide metabolism	0.000	0.998	0.001
D55.2 Anaemia due to disorders of glycolytic enzymes	0.000	0.998	0.001
D55.1 Anaemia due to other disorders of glutathione metabolism	0.000	0.998	0.001
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.000	0.998	0.001
D57.8 Other sickle-cell disorders	0.000	0.998	0.001
D57.3 Sickle-cell trait	0.000	0.998	0.001
D57.2 Double heterozygous sickling disorders	0.000	0.998	0.001
D57.1 Sickle-cell anaemia without crisis	0.000	0.998	0.001
D57.0 Sickle-cell anaemia with crisis	0.000	0.998	0.001
E24.0 Pituitary-dependent Cushing's disease	0.002	0.998	0.000
J03.9 Acute tonsillitis, unspecified	0.000	0.998	0.002
S71.1 Open wound of thigh	0.002	0.998	0.000
F23 Acute and transient psychotic disorders	0.000	0.998	0.002
E24.8 Other Cushing's syndrome	0.002	0.998	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.002	0.998	0.000
E24.3 Ectopic ACTH syndrome	0.002	0.998	0.000
E24.1 Nelson's syndrome	0.002	0.998	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.001	0.998	0.000
F28 Other nonorganic psychotic disorders	0.000	0.998	0.002
F24 Induced delusional disorder	0.000	0.998	0.002
F21 Schizotypal disorder	0.000	0.998	0.002
F31.6 Bipolar affective disorder, current episode mixed	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations