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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3743714
log Bayes Factor = <0.0001
Chromosome 16   position 66,583,705  (GRCh37) Explore rs3743714 on Ensembl!
Variant rs3743714 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I84.9 Unspecified haemorrhoids without complication
0.000 0.981 0.019
M48.06 Spinal stenosis (Lumbar region)
0.011 0.989 0.000
I84.1 Internal haemorrhoids with other complications
0.000 0.990 0.010
M48.0 Spinal stenosis
0.010 0.990 0.000
M48 Other spondylopathies
0.009 0.991 0.000
I84 Haemorrhoids
0.000 0.991 0.009
M48.07 Spinal stenosis (Lumbosacral region)
0.009 0.991 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.008 0.991 0.000
M45-M49 Spondylopathies
0.008 0.992 0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)
0.008 0.992 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.007 0.992 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.007 0.992 0.000
M48.04 Spinal stenosis (Thoracic region)
0.007 0.992 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.007 0.992 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.007 0.992 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.007 0.992 0.000
M48.02 Spinal stenosis (Cervical region)
0.007 0.993 0.000
I84.6 Residual haemorrhoidal skin tags
0.000 0.993 0.007
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.007 0.993 0.000
I84.0 Internal thrombosed haemorrhoids
0.000 0.993 0.007
I84.7 Unspecified thrombosed haemorrhoids
0.000 0.993 0.007
M48.9 Spondylopathy, unspecified
0.007 0.993 0.000
M48.8 Other specified spondylopathies
0.007 0.993 0.000
M48.4 Fatigue fracture of vertebra
0.007 0.993 0.000
M48.3 Traumatic spondylopathy
0.007 0.993 0.000
M48.2 Kissing spine
0.007 0.993 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.007 0.993 0.000
I84.4 External haemorrhoids with other complications
0.000 0.993 0.007
M17.9 Gonarthrosis, unspecified
0.007 0.993 0.000
I84.5 External haemorrhoids without complication
0.000 0.993 0.007
M17 Gonarthrosis [arthrosis of knee]
0.007 0.993 0.000
I84.3 External thrombosed haemorrhoids
0.000 0.993 0.006
M40-M43 Deforming dorsopathies
0.006 0.993 0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)
0.006 0.994 0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)
0.006 0.994 0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)
0.006 0.994 0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.006 0.994 0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)
0.006 0.994 0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)
0.006 0.994 0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)
0.006 0.994 0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)
0.006 0.994 0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)
0.006 0.994 0.000
M45 Ankylosing spondylitis
0.006 0.994 0.000
M17.0 Primary gonarthrosis, bilateral
0.006 0.994 0.000
M05-M14 Inflammatory polyarthropathies
0.006 0.994 0.000
M65-M68 Disorders of synovium and tendon
0.006 0.994 0.000
M15-M19 Arthrosis
0.006 0.994 0.000
M80-M85 Disorders of bone density and structure
0.006 0.994 0.000
M48.09 Spinal stenosis (Site unspecified)
0.006 0.994 0.000
M46 Other inflammatory spondylopathies
0.006 0.994 0.000
M49 Spondylopathies in diseases classified elsewhere
0.006 0.994 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.006 0.994 0.000
M86-M90 Other osteopathies
0.006 0.994 0.000
M67 Other disorders of synovium and tendon
0.006 0.994 0.000
M41 Scoliosis
0.006 0.994 0.000
M05 Seropositive rheumatoid arthritis
0.006 0.994 0.000
M91-M94 Chondropathies
0.006 0.994 0.000
M06 Other rheumatoid arthritis
0.006 0.994 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.005 0.994 0.000
M67.8 Other specified disorders of synovium and tendon
0.005 0.994 0.000
M43 Other deforming dorsopathies
0.005 0.995 0.000
M47 Spondylosis
0.005 0.995 0.000
M60-M63 Disorders of muscles
0.005 0.995 0.000
M00-M03 Infectious arthropathies
0.005 0.995 0.000
M84 Disorders of continuity of bone
0.005 0.995 0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)
0.005 0.995 0.000
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)
0.005 0.995 0.000
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)
0.005 0.995 0.000
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)
0.005 0.995 0.000
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)
0.005 0.995 0.000
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)
0.005 0.995 0.000
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)
0.005 0.995 0.000
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)
0.005 0.995 0.000
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)
0.005 0.995 0.000
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)
0.005 0.995 0.000
M48.29 Kissing spine (Site unspecified)
0.005 0.995 0.000
M48.28 Kissing spine (Sacral and sacrococcygeal region)
0.005 0.995 0.000
M48.27 Kissing spine (Lumbosacral region)
0.005 0.995 0.000
M48.26 Kissing spine (Lumbar region)
0.005 0.995 0.000
M48.25 Kissing spine (Thoracolumbar region)
0.005 0.995 0.000
M48.24 Kissing spine (Thoracic region)
0.005 0.995 0.000
M48.23 Kissing spine (Cervicothoracic region)
0.005 0.995 0.000
M48.22 Kissing spine (Cervical region)
0.005 0.995 0.000
M48.21 Kissing spine (Occipito-atlanto-axial region)
0.005 0.995 0.000
M48.20 Kissing spine (Multiple sites in spine)
0.005 0.995 0.000
M48.39 Traumatic spondylopathy (Site unspecified)
0.005 0.995 0.000
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)
0.005 0.995 0.000
M48.37 Traumatic spondylopathy (Lumbosacral region)
0.005 0.995 0.000
M48.36 Traumatic spondylopathy (Lumbar region)
0.005 0.995 0.000
M48.35 Traumatic spondylopathy (Thoracolumbar region)
0.005 0.995 0.000
M48.34 Traumatic spondylopathy (Thoracic region)
0.005 0.995 0.000
M48.33 Traumatic spondylopathy (Cervicothoracic region)
0.005 0.995 0.000
M48.32 Traumatic spondylopathy (Cervical region)
0.005 0.995 0.000
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)
0.005 0.995 0.000
M48.30 Traumatic spondylopathy (Multiple sites in spine)
0.005 0.995 0.000
M48.49 Fatigue fracture of vertebra (Site unspecified)
0.005 0.995 0.000
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)
0.005 0.995 0.000
M48.47 Fatigue fracture of vertebra (Lumbosacral region)
0.005 0.995 0.000
M48.46 Fatigue fracture of vertebra (Lumbar region)
0.005 0.995 0.000
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)
0.005 0.995 0.000
M48.44 Fatigue fracture of vertebra (Thoracic region)
0.005 0.995 0.000
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)
0.005 0.995 0.000
M48.42 Fatigue fracture of vertebra (Cervical region)
0.005 0.995 0.000
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)
0.005 0.995 0.000
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)
0.005 0.995 0.000
M48.89 Other specified spondylopathies (Site unspecified)
0.005 0.995 0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)
0.005 0.995 0.000
M48.87 Other specified spondylopathies (Lumbosacral region)
0.005 0.995 0.000
M48.86 Other specified spondylopathies (Lumbar region)
0.005 0.995 0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)
0.005 0.995 0.000
M48.84 Other specified spondylopathies (Thoracic region)
0.005 0.995 0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)
0.005 0.995 0.000
M48.82 Other specified spondylopathies (Cervical region)
0.005 0.995 0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)
0.005 0.995 0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)
0.005 0.995 0.000
M48.99 Spondylopathy, unspecified (Site unspecified)
0.005 0.995 0.000
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.005 0.995 0.000
M48.97 Spondylopathy, unspecified (Lumbosacral region)
0.005 0.995 0.000
M48.96 Spondylopathy, unspecified (Lumbar region)
0.005 0.995 0.000
M48.95 Spondylopathy, unspecified (Thoracolumbar region)
0.005 0.995 0.000
M48.94 Spondylopathy, unspecified (Thoracic region)
0.005 0.995 0.000
M48.93 Spondylopathy, unspecified (Cervicothoracic region)
0.005 0.995 0.000
M48.92 Spondylopathy, unspecified (Cervical region)
0.005 0.995 0.000
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)
0.005 0.995 0.000
M48.90 Spondylopathy, unspecified (Multiple sites in spine)
0.005 0.995 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.005 0.995 0.000
M17.3 Other posttraumatic gonarthrosis
0.005 0.995 0.000
M41.9 Scoliosis, unspecified
0.005 0.995 0.000
M21 Other acquired deformities of limbs
0.005 0.995 0.000
M21.1 Varus deformity, not elsewhere classified
0.005 0.995 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.005 0.995 0.000
M11 Other crystal arthropathies
0.005 0.995 0.000
M20-M25 Other joint disorders
0.005 0.995 0.000
M06.9 Rheumatoid arthritis, unspecified
0.005 0.995 0.000
M17.5 Other secondary gonarthrosis
0.005 0.995 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.005 0.995 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.005 0.995 0.000
M42 Spinal osteochondrosis
0.005 0.995 0.000
M40 Kyphosis and lordosis
0.005 0.995 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.005 0.995 0.000
M80 Osteoporosis with pathological fracture
0.005 0.995 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.005 0.995 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.005 0.995 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.005 0.995 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.005 0.995 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.005 0.995 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.005 0.995 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.005 0.995 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.005 0.995 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.005 0.995 0.000
M85 Other disorders of bone density and structure
0.005 0.995 0.000
M43.1 Spondylolisthesis
0.005 0.995 0.000
M14 Arthropathies in other diseases classified elsewhere
0.005 0.995 0.000
M12 Other specific arthropathies
0.005 0.995 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.005 0.995 0.000
M08 Juvenile arthritis
0.005 0.995 0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.005 0.995 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.005 0.995 0.000
M66 Spontaneous rupture of synovium and tendon
0.005 0.995 0.000
M89 Other disorders of bone
0.005 0.995 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.005 0.995 0.000
M15 Polyarthrosis
0.005 0.995 0.000
M83 Adult osteomalacia
0.005 0.995 0.000
M82 Osteoporosis in diseases classified elsewhere
0.005 0.995 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.005 0.995 0.000
M46.8 Other specified inflammatory spondylopathies
0.004 0.995 0.000
M46.5 Other infective spondylopathies
0.004 0.995 0.000
M46.4 Discitis, unspecified
0.004 0.995 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.004 0.995 0.000
M46.2 Osteomyelitis of vertebra
0.004 0.995 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.004 0.995 0.000
M46.0 Spinal enthesopathy
0.004 0.995 0.000
M90 Osteopathies in diseases classified elsewhere
0.004 0.995 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.005 0.995 0.000
M49.8 Spondylopathy in other diseases classified elsewhere
0.004 0.995 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.004 0.995 0.000
M49.4 Neuropathic spondylopathy
0.004 0.995 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.004 0.995 0.000
M49.2 Enterobacterial spondylitis
0.004 0.995 0.000
M49.1 Brucella spondylitis
0.004 0.995 0.000
M49.0 Tuberculosis of spine
0.004 0.995 0.000
M18 Arthrosis of first carpometacarpal joint
0.005 0.995 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.004 0.995 0.000
M88 Paget's disease of bone [osteitis deformans]
0.004 0.995 0.000
M06.4 Inflammatory polyarthropathy
0.004 0.995 0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)
0.004 0.995 0.000
M94 Other disorders of cartilage
0.004 0.995 0.000
M50-M54 Other dorsopathies
0.005 0.995 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.004 0.995 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.004 0.995 0.000
M47.8 Other spondylosis
0.004 0.995 0.000
M07 Psoriatic and enteropathic arthropathies
0.004 0.996 0.000
M84.0 Malunion of fracture
0.004 0.996 0.000
M81 Osteoporosis without pathological fracture
0.004 0.996 0.000
M41.8 Other forms of scoliosis
0.004 0.996 0.000
M41.5 Other secondary scoliosis
0.004 0.996 0.000
M41.4 Neuromuscular scoliosis
0.004 0.996 0.000
M41.3 Thoracogenic scoliosis
0.004 0.996 0.000
M41.2 Other idiopathic scoliosis
0.004 0.996 0.000
M41.1 Juvenile idiopathic scoliosis
0.004 0.996 0.000
M41.0 Infantile idiopathic scoliosis
0.004 0.996 0.000
M67.9 Disorder of synovium and tendon, unspecified
0.004 0.996 0.000
M67.4 Ganglion
0.004 0.996 0.000
M67.3 Transient synovitis
0.004 0.996 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.004 0.996 0.000
M67.1 Other contracture of tendon (sheath)
0.004 0.996 0.000
M67.0 Short Achilles tendon (acquired)
0.004 0.996 0.000
M86 Osteomyelitis
0.004 0.996 0.000
M19 Other arthrosis
0.004 0.996 0.000
M65 Synovitis and tenosynovitis
0.004 0.996 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.004 0.996 0.000
M05.8 Other seropositive rheumatoid arthritis
0.004 0.996 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.004 0.996 0.000
M05.2 Rheumatoid vasculitis
0.004 0.996 0.000
M05.1 Rheumatoid lung disease
0.004 0.996 0.000
M05.0 Felty's syndrome
0.004 0.996 0.000
M21.2 Flexion deformity
0.004 0.996 0.000
M93 Other osteochondropathies
0.004 0.996 0.000
M92 Other juvenile osteochondrosis
0.004 0.996 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.004 0.996 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.004 0.996 0.000
M47.1 Other spondylosis with myelopathy
0.004 0.996 0.000
M06.8 Other specified rheumatoid arthritis
0.004 0.996 0.000
M06.3 Rheumatoid nodule
0.004 0.996 0.000
M06.2 Rheumatoid bursitis
0.004 0.996 0.000
M06.1 Adult-onset Still's disease
0.004 0.996 0.000
M87 Osteonecrosis
0.004 0.996 0.000
M99 Biomechanical lesions, not elsewhere classified
0.004 0.996 0.000
M06.0 Seronegative rheumatoid arthritis
0.004 0.996 0.000
M11.2 Other chondrocalcinosis
0.004 0.996 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.004 0.996 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.004 0.996 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.004 0.996 0.000
M43.9 Deforming dorsopathy, unspecified
0.004 0.996 0.000
M43.8 Other specified deforming dorsopathies
0.004 0.996 0.000
M43.6 Torticollis
0.004 0.996 0.000
M43.5 Other recurrent vertebral subluxation
0.004 0.996 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.004 0.996 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.004 0.996 0.000
M43.2 Other fusion of spine
0.004 0.996 0.000
M43.0 Spondylolysis
0.004 0.996 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.004 0.996 0.000
M51.2 Other specified intervertebral disk displacement
0.004 0.996 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.004 0.996 0.000
M62 Other disorders of muscle
0.004 0.996 0.000
M61 Calcification and ossification of muscle
0.004 0.996 0.000
M60 Myositis
0.004 0.996 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.004 0.996 0.000
M02 Reactive arthropathies
0.004 0.996 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.004 0.996 0.000
M00 Pyogenic arthritis
0.004 0.996 0.000
M51 Other intervertebral disk disorders
0.004 0.996 0.000
M84.9 Disorder of continuity of bone, unspecified
0.004 0.996 0.000
M84.8 Other disorders of continuity of bone
0.004 0.996 0.000
M84.4 Pathological fracture, not elsewhere classified
0.004 0.996 0.000
M84.3 Stress fracture, not elsewhere classified
0.004 0.996 0.000
M84.2 Delayed union of fracture
0.004 0.996 0.000
M13 Other arthritis
0.004 0.996 0.000
M70-M79 Other soft tissue disorders
0.004 0.996 0.000
M21.0 Valgus deformity, not elsewhere classified
0.004 0.996 0.000
M31 Other necrotising vasculopathies
0.004 0.996 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.004 0.996 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.004 0.996 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.004 0.996 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.004 0.996 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.004 0.996 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.004 0.996 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.004 0.996 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.004 0.996 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.004 0.996 0.000
M19.0 Primary arthrosis of other joints
0.004 0.996 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.004 0.996 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.004 0.996 0.000
M24 Other specific joint derangements
0.004 0.996 0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.004 0.996 0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.004 0.996 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.004 0.996 0.000
M41.94 Scoliosis, unspecified (Thoracic region)
0.004 0.996 0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)
0.004 0.996 0.000
M41.92 Scoliosis, unspecified (Cervical region)
0.004 0.996 0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)
0.004 0.996 0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)
0.004 0.996 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.004 0.996 0.000
M21.9 Acquired deformity of limb, unspecified
0.004 0.996 0.000
M21.8 Other specified acquired deformities of limbs
0.004 0.996 0.000
M21.7 Unequal limb length (acquired)
0.004 0.996 0.000
M21.6 Other acquired deformities of ankle and foot
0.004 0.996 0.000
M21.4 Flat foot [pes planus] (acquired)
0.004 0.996 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.004 0.996 0.000
M89.9 Disorder of bone, unspecified
0.004 0.996 0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)
0.004 0.996 0.000
M21.18 Varus deformity, not elsewhere classified (Other)
0.004 0.996 0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)
0.004 0.996 0.000
M21.14 Varus deformity, not elsewhere classified (Hand)
0.004 0.996 0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)
0.004 0.996 0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)
0.004 0.996 0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)
0.004 0.996 0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)
0.004 0.996 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.004 0.996 0.000
M34 Systemic sclerosis
0.004 0.996 0.000
M33 Dermatopolymyositis
0.004 0.996 0.000
M32 Systemic lupus erythematosus
0.004 0.996 0.000
M30 Polyarteritis nodosa and related conditions
0.004 0.996 0.000
M11.9 Crystal arthropathy, unspecified
0.004 0.996 0.000
M11.8 Other specified crystal arthropathies
0.004 0.996 0.000
M11.1 Familial chondrocalcinosis
0.004 0.996 0.000
M11.0 Hydroxyapatite deposition disease
0.004 0.996 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.004 0.996 0.000
M77 Other enthesopathies
0.004 0.996 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.004 0.996 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.004 0.996 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.004 0.996 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.004 0.996 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.004 0.996 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.004 0.996 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.004 0.996 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.004 0.996 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.004 0.996 0.000
M47.2 Other spondylosis with radiculopathy
0.004 0.996 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.004 0.996 0.000
M40.5 Lordosis, unspecified
0.004 0.996 0.000
M40.4 Other lordosis
0.004 0.996 0.000
M40.3 Flatback syndrome
0.004 0.996 0.000
M40.2 Other and unspecified kyphosis
0.004 0.996 0.000
M40.1 Other secondary kyphosis
0.004 0.996 0.000
M40.0 Postural kyphosis
0.004 0.996 0.000
M42.9 Spinal osteochondrosis, unspecified
0.004 0.996 0.000
M42.1 Adult osteochondrosis of spine
0.004 0.996 0.000
M42.0 Juvenile osteochondrosis of spine
0.004 0.996 0.000
M90.7 Fracture of bone in neoplastic disease
0.004 0.996 0.000
M85.8 Other specified disorders of bone density and structure
0.004 0.996 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.004 0.996 0.000
M94.8 Other specified disorders of cartilage
0.004 0.996 0.000
M84.03 Malunion of fracture (Forearm)
0.004 0.996 0.000
M21.3 Wrist or foot drop (acquired)
0.004 0.996 0.000
M80.8 Other osteoporosis with pathological fracture
0.004 0.996 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.004 0.996 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.004 0.996 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.004 0.996 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.004 0.996 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.004 0.996 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.004 0.996 0.000
M21.26 Flexion deformity (Lower leg)
0.004 0.996 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.004 0.996 0.000
M88.9 Paget's disease of bone, unspecified
0.004 0.996 0.000
M10 Gout
0.004 0.996 0.000
M85.9 Disorder of bone density and structure, unspecified
0.003 0.996 0.000
M85.6 Other cyst of bone
0.003 0.996 0.000
M85.5 Aneurysmal bone cyst
0.003 0.996 0.000
M85.4 Solitary bone cyst
0.003 0.996 0.000
M85.3 Osteitis condensans
0.003 0.996 0.000
M85.2 Hyperostosis of skull
0.003 0.996 0.000
M85.1 Skeletal fluorosis
0.003 0.996 0.000
M85.0 Fibrous dysplasia (monostotic)
0.003 0.996 0.000
M77.1 Lateral epicondylitis
0.004 0.996 0.000
M25 Other joint disorders, not elsewhere classified
0.004 0.996 0.000
M43.19 Spondylolisthesis (Site unspecified)
0.003 0.996 0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)
0.003 0.996 0.000
M43.15 Spondylolisthesis (Thoracolumbar region)
0.003 0.996 0.000
M43.14 Spondylolisthesis (Thoracic region)
0.003 0.996 0.000
M43.13 Spondylolisthesis (Cervicothoracic region)
0.003 0.996 0.000
M43.12 Spondylolisthesis (Cervical region)
0.003 0.996 0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)
0.003 0.996 0.000
M43.10 Spondylolisthesis (Multiple sites in spine)
0.003 0.996 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.003 0.996 0.000
M08.9 Juvenile arthritis, unspecified
0.003 0.996 0.000
M08.8 Other juvenile arthritis
0.003 0.996 0.000
M08.4 Pauciarticular juvenile arthritis
0.003 0.996 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.003 0.996 0.000
M08.2 Juvenile arthritis with systemic onset
0.003 0.996 0.000
M08.1 Juvenile ankylosing spondylitis
0.003 0.996 0.000
M08.0 Juvenile rheumatoid arthritis
0.003 0.996 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.003 0.996 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.003 0.996 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.003 0.996 0.000
M09.0 Juvenile arthritis in psoriasis
0.003 0.996 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.003 0.996 0.000
M12.5 Traumatic arthropathy
0.003 0.996 0.000
M12.4 Intermittent hydrarthrosis
0.003 0.996 0.000
M12.3 Palindromic rheumatism
0.003 0.996 0.000
M12.2 Villonodular synovitis (pigmented)
0.003 0.996 0.000
M12.1 Kaschin-Beck disease
0.003 0.996 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.003 0.996 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.003 0.996 0.000
M14.6 Neuropathic arthropathy
0.003 0.996 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.003 0.996 0.000
M14.4 Arthropathy in amyloidosis
0.003 0.996 0.000
M14.3 Lipoid dermatoarthritis
0.003 0.996 0.000
M14.2 Diabetic arthropathy
0.003 0.996 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.003 0.996 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.003 0.996 0.000
M89.8 Other specified disorders of bone
0.003 0.996 0.000
M89.6 Osteopathy after poliomyelitis
0.003 0.996 0.000
M89.5 Osteolysis
0.003 0.996 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.003 0.996 0.000
M89.3 Hypertrophy of bone
0.003 0.996 0.000
M89.2 Other disorders of bone development and growth
0.003 0.996 0.000
M89.1 Epiphyseal arrest
0.003 0.996 0.000
M89.0 Algoneurodystrophy
0.003 0.996 0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate
0.003 0.996 0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified
0.003 0.996 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.003 0.996 0.000
M96.5 Postradiation scoliosis
0.003 0.996 0.000
M96.4 Postsurgical lordosis
0.003 0.996 0.000
M96.3 Postlaminectomy kyphosis
0.003 0.996 0.000
M96.2 Postradiation kyphosis
0.003 0.996 0.000
M15.9 Polyarthrosis, unspecified
0.003 0.996 0.000
M15.0 Primary generalised (osteo)arthrosis
0.003 0.996 0.000
M15.8 Other polyarthrosis
0.003 0.996 0.000
M15.4 Erosive (osteo)arthrosis
0.003 0.996 0.000
M15.3 Secondary multiple arthrosis
0.003 0.996 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.003 0.996 0.000
M15.1 Heberden's nodes (with arthropathy)
0.003 0.996 0.000
M66.5 Spontaneous rupture of unspecified tendon
0.003 0.996 0.000
M66.4 Spontaneous rupture of other tendons
0.003 0.996 0.000
M66.3 Spontaneous rupture of flexor tendons
0.003 0.996 0.000
M66.2 Spontaneous rupture of extensor tendons
0.003 0.996 0.000
M66.1 Rupture of synovium
0.003 0.996 0.000
M66.0 Rupture of popliteal cyst
0.003 0.996 0.000
M68.8 Other disorders of synovium and tendon in diseases classified elsewhere
0.003 0.996 0.000
M68.0 Synovitis and tenosynovitis in bacterial diseases classified elsewhere
0.003 0.996 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.003 0.996 0.000
M77.12 Lateral epicondylitis (Upper arm)
0.004 0.996 0.000
M82.8 Osteoporosis in other diseases classified elsewhere
0.003 0.996 0.000
M82.1 Osteoporosis in endocrine disorders
0.003 0.996 0.000
M82.0 Osteoporosis in multiple myelomatosis
0.003 0.996 0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm
0.003 0.996 0.000
M83.9 Adult osteomalacia, unspecified
0.003 0.996 0.000
M83.8 Other adult osteomalacia
0.003 0.996 0.000
M83.5 Other drug-induced osteomalacia in adults
0.003 0.996 0.000
M83.4 Aluminum bone disease
0.003 0.996 0.000
M83.3 Adult osteomalacia due to malnutrition
0.003 0.996 0.000
M83.2 Adult osteomalacia due to malabsorption
0.003 0.996 0.000
M83.1 Senile osteomalacia
0.003 0.996 0.000
M83.0 Puerperal osteomalacia
0.003 0.996 0.000
M46.09 Spinal enthesopathy (Site unspecified)
0.003 0.996 0.000
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)
0.003 0.996 0.000
M46.07 Spinal enthesopathy (Lumbosacral region)
0.003 0.996 0.000
M46.06 Spinal enthesopathy (Lumbar region)
0.003 0.996 0.000
M46.05 Spinal enthesopathy (Thoracolumbar region)
0.003 0.996 0.000
M46.04 Spinal enthesopathy (Thoracic region)
0.003 0.996 0.000
M46.03 Spinal enthesopathy (Cervicothoracic region)
0.003 0.996 0.000
M46.02 Spinal enthesopathy (Cervical region)
0.003 0.996 0.000
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)
0.003 0.996 0.000
M46.00 Spinal enthesopathy (Multiple sites in spine)
0.003 0.996 0.000
M46.19 Sacroiliitis, not elsewhere classified-Site unspe
0.003 0.996 0.000
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ
0.003 0.996 0.000
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral
0.003 0.996 0.000
M46.16 Sacroiliitis, not elsewhere classified-Lumbar
0.003 0.996 0.000
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar
0.003 0.996 0.000
M46.14 Sacroiliitis, not elsewhere classified-Thoracic
0.003 0.996 0.000
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic
0.003 0.996 0.000
M46.12 Sacroiliitis, not elsewhere classified-Cervical
0.003 0.996 0.000
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl
0.003 0.996 0.000
M46.10 Sacroiliitis, not elsewhere classified-Mult site
0.003 0.996 0.000
M46.29 Osteomyelitis of vertebra (Site unspecified)
0.003 0.996 0.000
M46.28 Osteomyelitis of vertebra (Sacral and sacrococcygeal region)
0.003 0.996 0.000
M46.27 Osteomyelitis of vertebra (Lumbosacral region)
0.003 0.996 0.000
M46.26 Osteomyelitis of vertebra (Lumbar region)
0.003 0.996 0.000
M46.25 Osteomyelitis of vertebra (Thoracolumbar region)
0.003 0.996 0.000
M46.24 Osteomyelitis of vertebra (Thoracic region)
0.003 0.996 0.000
M46.23 Osteomyelitis of vertebra (Cervicothoracic region)
0.003 0.996 0.000
M46.22 Osteomyelitis of vertebra (Cervical region)
0.003 0.996 0.000
M46.21 Osteomyelitis of vertebra (Occipito-atlanto-axial region)
0.003 0.996 0.000
M46.20 Osteomyelitis of vertebra (Multiple sites in spine)
0.003 0.996 0.000
M46.39 Infection of intervertebral disc (pyogenic) (Site unspecified)
0.003 0.996 0.000
M46.38 Infection of intervertebral disc (pyogenic) (Sacral and sacrococcygeal region)
0.003 0.996 0.000
M46.37 Infection of intervertebral disc (pyogenic) (Lumbosacral region)
0.003 0.996 0.000
M46.36 Infection of intervertebral disc (pyogenic) (Lumbar region)
0.003 0.996 0.000
M46.35 Infection of intervertebral disc (pyogenic) (Thoracolumbar region)
0.003 0.996 0.000
M46.34 Infection of intervertebral disc (pyogenic) (Thoracic region)
0.003 0.996 0.000
M46.33 Infection of intervertebral disc (pyogenic) (Cervicothoracic region)
0.003 0.996 0.000
M46.32 Infection of intervertebral disc (pyogenic) (Cervical region)
0.003 0.996 0.000
M46.31 Infection of intervertebral disc (pyogenic) (Occipito-atlanto-axial region)
0.003 0.996 0.000
M46.30 Infection of intervertebral disc (pyogenic) (Multiple sites in spine)
0.003 0.996 0.000
M46.49 Discitis, unspecified (Site unspecified)
0.003 0.996 0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)
0.003 0.996 0.000
M46.47 Discitis, unspecified (Lumbosacral region)
0.003 0.996 0.000
M46.46 Discitis, unspecified (Lumbar region)
0.003 0.996 0.000
M46.45 Discitis, unspecified (Thoracolumbar region)
0.003 0.996 0.000
M46.44 Discitis, unspecified (Thoracic region)
0.003 0.996 0.000
M46.43 Discitis, unspecified (Cervicothoracic region)
0.003 0.996 0.000
M46.42 Discitis, unspecified (Cervical region)
0.003 0.996 0.000
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)
0.003 0.996 0.000
M46.40 Discitis, unspecified (Multiple sites in spine)
0.003 0.996 0.000
M46.59 Other infective spondylopathies (Site unspecified)
0.003 0.996 0.000
M46.58 Other infective spondylopathies (Sacral and sacrococcygeal region)
0.003 0.996 0.000
M46.57 Other infective spondylopathies (Lumbosacral region)
0.003 0.996 0.000
M46.56 Other infective spondylopathies (Lumbar region)
0.003 0.996 0.000
M46.55 Other infective spondylopathies (Thoracolumbar region)
0.003 0.996 0.000
M46.54 Other infective spondylopathies (Thoracic region)
0.003 0.996 0.000
M46.53 Other infective spondylopathies (Cervicothoracic region)
0.003 0.996 0.000
M46.52 Other infective spondylopathies (Cervical region)
0.003 0.996 0.000
M46.51 Other infective spondylopathies (Occipito-atlanto-axial region)
0.003 0.996 0.000
M46.50 Other infective spondylopathies (Multiple sites in spine)
0.003 0.996 0.000
M46.89 Other specified inflammatory spondylopathies (Site unspecified)
0.003 0.996 0.000
M46.88 Other specified inflammatory spondylopathies (Sacral and sacrococcygeal region)
0.003 0.996 0.000
M46.87 Other specified inflammatory spondylopathies (Lumbosacral region)
0.003 0.996 0.000
M46.86 Other specified inflammatory spondylopathies (Lumbar region)
0.003 0.996 0.000
M46.85 Other specified inflammatory spondylopathies (Thoracolumbar region)
0.003 0.996 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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