TreeWAS – Variant ID: rs374748

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H04.5 Stenosis and insufficiency of lachrymal passages	0.150	0.850	0.000
H33.3 Retinal breaks without detachment	0.038	0.962	0.000
H33.0 Retinal detachment with retinal break	0.038	0.962	0.000
H33 Retinal detachments and breaks	0.035	0.965	0.000
H65.3 Chronic mucoid otitis media	0.000	0.967	0.033
H04 Disorders of lachrymal system	0.032	0.968	0.000
H33.5 Other retinal detachments	0.028	0.972	0.000
H65 Nonsuppurative otitis media	0.000	0.972	0.028
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.973	0.027
H04.3 Acute and unspecified inflammation of lachrymal passages	0.026	0.974	0.000
H33.1 Retinoschisis and retinal cysts	0.026	0.974	0.000
H04.4 Chronic inflammation of lachrymal passages	0.024	0.976	0.000
H04.0 Dacryoadenitis	0.023	0.977	0.000
H33.4 Traction detachment of retina	0.022	0.977	0.000
T40.2 Other opioids	0.022	0.978	0.000
H04.8 Other disorders of lachrymal system	0.021	0.978	0.000
H65.2 Chronic serous otitis media	0.000	0.978	0.021
H04.2 Epiphora	0.021	0.979	0.000
H04.9 Disorder of lachrymal system, unspecified	0.021	0.979	0.000
H65.1 Other acute nonsuppurative otitis media	0.000	0.979	0.021
H65.4 Other chronic nonsuppurative otitis media	0.000	0.980	0.020
H65.0 Acute serous otitis media	0.000	0.981	0.019
H04.6 Other changes in lachrymal passages	0.019	0.981	0.000
H04.1 Other disorders of lachrymal gland	0.017	0.983	0.000
K61.0 Anal abscess	0.000	0.985	0.015
G56.2 Lesion of ulnar nerve	0.000	0.986	0.014
H43.8 Other disorders of vitreous body	0.013	0.987	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.012	0.988	0.000
R40.0 Somnolence	0.000	0.988	0.012
R04.0 Epistaxis	0.011	0.989	0.000
H43 Disorders of vitreous body	0.010	0.990	0.000
H72.0 Central perforation of tympanic membrane	0.000	0.990	0.010
H30-H36 Disorders of choroid and retina	0.010	0.990	0.000
R40.2 Coma, unspecified	0.000	0.990	0.010
T40.6 Other and unspecified narcotics	0.009	0.990	0.000
R40 Somnolence, stupor and coma	0.000	0.990	0.010
T40.5 Cocaine	0.009	0.991	0.000
T40.3 Methadone	0.009	0.991	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.009	0.991	0.000
T40.8 Lysergide [LSD]	0.009	0.991	0.000
T40.7 Cannabis (derivatives)	0.009	0.991	0.000
T40.0 Opium	0.009	0.991	0.000
T40.1 Heroin	0.009	0.991	0.000
T40.4 Other synthetic narcotics	0.008	0.992	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.000	0.992	0.008
K61 Abscess of anal and rectal regions	0.000	0.992	0.008
H43.3 Other vitreous opacities	0.008	0.992	0.000
H43-H45 Disorders of vitreous body and globe	0.008	0.992	0.000
H43.2 Crystalline deposits in vitreous body	0.008	0.992	0.000
H35 Other retinal disorders	0.008	0.992	0.000
H43.9 Disorder of vitreous body, unspecified	0.008	0.992	0.000
R40.1 Stupor	0.000	0.992	0.008
T42.4 Benzodiazepines	0.008	0.992	0.000
H43.0 Vitreous prolapse	0.007	0.992	0.000
H35.4 Peripheral retinal degeneration	0.007	0.993	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.007	0.993	0.000
K61.1 Rectal abscess	0.000	0.993	0.007
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.007	0.993	0.000
H43.1 Vitreous haemorrhage	0.007	0.993	0.000
H33.2 Serous retinal detachment	0.007	0.993	0.000
H35.0 Background retinopathy and retinal vascular changes	0.007	0.993	0.000
N20.0 Calculus of kidney	0.007	0.993	0.000
Chapter VII Diseases of the eye and adnexa	0.006	0.994	0.000
K61.3 Ischiorectal abscess	0.000	0.994	0.006
H30 Chorioretinal inflammation	0.006	0.994	0.000
H72 Perforation of tympanic membrane	0.000	0.994	0.006
H31 Other disorders of choroid	0.006	0.994	0.000
H35.7 Separation of retinal layers	0.006	0.994	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.006	0.994	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.994	0.006
K61.2 Anorectal abscess	0.000	0.994	0.006
H35.1 Retinopathy of prematurity	0.006	0.994	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.006	0.994	0.000
H35.8 Other specified retinal disorders	0.006	0.994	0.000
H35.5 Hereditary retinal dystrophy	0.006	0.994	0.000
H44 Disorders of globe	0.006	0.994	0.000
H10-H13 Disorders of conjunctiva	0.006	0.994	0.000
H35.9 Retinal disorder, unspecified	0.006	0.994	0.000
K61.4 Intrasphincteric abscess	0.000	0.994	0.006
H35.2 Other proliferative retinopathy	0.005	0.994	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.005	0.994	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.006	0.994	0.000
H72.1 Attic perforation of tympanic membrane	0.000	0.994	0.005
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.005	0.994	0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.005	0.994	0.000
H49 Paralytic strabismus	0.005	0.995	0.000
H65-H75 Diseases of middle ear and mastoid	0.000	0.995	0.005
H05 Disorders of orbit	0.005	0.995	0.000
H44.2 Degenerative myopia	0.005	0.995	0.000
O02.1 Missed abortion	0.005	0.995	0.000
H35.6 Retinal haemorrhage	0.005	0.995	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.005	0.995	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.005	0.995	0.000
H11 Other disorders of conjunctiva	0.005	0.995	0.000
H49.0 Third [oculomotor] nerve palsy	0.005	0.995	0.000
N97.9 Female infertility, unspecified	0.000	0.995	0.005
H30.2 Posterior cyclitis	0.005	0.995	0.000
M94.8 Other specified disorders of cartilage	0.000	0.995	0.005
H30.8 Other chorioretinal inflammations	0.005	0.995	0.000
H30.1 Disseminated chorioretinal inflammation	0.005	0.995	0.000
H30.0 Focal chorioretinal inflammation	0.005	0.995	0.000
H36 Retinal disorders in diseases classified elsewhere	0.005	0.995	0.000
H05.8 Other disorders of orbit	0.005	0.995	0.000
H31.3 Choroidal haemorrhage and rupture	0.005	0.995	0.000
H31.9 Disorder of choroid, unspecified	0.005	0.995	0.000
H45.0 Vitreous haemorrhage in diseases classified elsewhere	0.005	0.995	0.000
H31.4 Choroidal detachment	0.004	0.995	0.000
H31.2 Hereditary choroidal dystrophy	0.004	0.995	0.000
H31.1 Choroidal degeneration	0.004	0.995	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.005	0.995	0.000
H45.8 Other disorders of vitreous body and globe in diseases classified elsewhere	0.004	0.995	0.000
H45.1 Endophthalmitis in diseases classified elsewhere	0.004	0.995	0.000
T42.3 Barbiturates	0.005	0.995	0.000
H44.9 Disorder of globe, unspecified	0.004	0.995	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.004	0.995	0.000
T42.0 Hydantoin derivatives	0.004	0.995	0.000
H49.2 Sixth [abducent] nerve palsy	0.004	0.995	0.000
H49.1 Fourth [trochlear] nerve palsy	0.004	0.995	0.000
H11.8 Other specified disorders of conjunctiva	0.004	0.995	0.000
H35.3 Degeneration of macula and posterior pole	0.005	0.995	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.004	0.995	0.000
T42.2 Succinimides and oxazolidinediones	0.004	0.995	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.004	0.995	0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere	0.004	0.996	0.000
H55-H59 Other disorders of eye and adnexa	0.004	0.996	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.004	0.996	0.000
H10 Conjunctivitis	0.004	0.996	0.000
H44.8 Other disorders of globe	0.004	0.996	0.000
H44.6 Retained (old) intraocular foreign body, magnetic	0.004	0.996	0.000
H44.3 Other degenerative disorders of globe	0.004	0.996	0.000
H49.8 Other paralytic strabismus	0.004	0.996	0.000
M94.88 Other specified disorders of cartilage (Other)	0.000	0.996	0.004
H44.1 Other endophthalmitis	0.004	0.996	0.000
H51 Other disorders of binocular movement	0.004	0.996	0.000
H44.4 Hypotony of eye	0.004	0.996	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.004	0.996	0.000
H72.2 Other marginal perforations of tympanic membrane	0.000	0.996	0.004
H34 Retinal vascular occlusions	0.004	0.996	0.000
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere	0.004	0.996	0.000
H05.4 Enophthalmos	0.004	0.996	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.004	0.996	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.004	0.996	0.000
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere	0.004	0.996	0.000
H58.8 Visual disturbances in diseases classified elsewhere	0.004	0.996	0.000
H31.8 Other specified disorders of choroid	0.004	0.996	0.000
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.004	0.996	0.000
H49.3 Total (external) ophthalmoplegia	0.004	0.996	0.000
H72.8 Other perforations of tympanic membrane	0.000	0.996	0.004
H44.5 Degenerated conditions of globe	0.004	0.996	0.000
H05.3 Deformity of orbit	0.004	0.996	0.000
H11.1 Conjunctival degenerations and deposits	0.004	0.996	0.000
H31.0 Chorioretinal scars	0.004	0.996	0.000
H49.9 Paralytic strabismus, unspecified	0.004	0.996	0.000
H05.1 Chronic inflammatory disorders of orbit	0.004	0.996	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.996	0.004
H67 Otitis media in diseases classified elsewhere	0.000	0.996	0.004
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.004	0.996	0.000
H05.9 Disorder of orbit, unspecified	0.004	0.996	0.000
H49.4 Progressive external ophthalmoplegia	0.004	0.996	0.000
H68 Eustachian salpingitis and obstruction	0.000	0.996	0.004
E04.2 Non-toxic multinodular goitre	0.004	0.996	0.000
H70 Mastoiditis and related conditions	0.000	0.996	0.004
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.004	0.996	0.000
H69 Other disorders of Eustachian tube	0.000	0.996	0.004
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.004	0.996	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.004	0.996	0.000
H30.9 Chorioretinal inflammation, unspecified	0.003	0.996	0.001
T41 Poisoning by anaesthetics and therapeutic gases	0.004	0.996	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.996	0.000
M94.81 Other specified disorders of cartilage (Shoulder region)	0.000	0.996	0.004
H44.0 Purulent endophthalmitis	0.004	0.996	0.000
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.000	0.996	0.004
M94.84 Other specified disorders of cartilage (Hand)	0.000	0.996	0.004
M94.83 Other specified disorders of cartilage (Forearm)	0.000	0.996	0.004
M94.82 Other specified disorders of cartilage (Upper arm)	0.000	0.996	0.004
M94.80 Other specified disorders of cartilage (Multiple sites)	0.000	0.996	0.004
T47.1 Other antacids and anti-gastric-secretion drugs	0.004	0.996	0.000
T47.2 Stimulant laxatives	0.004	0.996	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.004	0.996	0.000
H05.0 Acute inflammation of orbit	0.004	0.996	0.000
H10.4 Chronic conjunctivitis	0.004	0.996	0.000
M50.0 Cervical disk disorder with myelopathy	0.004	0.996	0.000
T42.1 Iminostilbenes	0.003	0.996	0.000
H11.3 Conjunctival haemorrhage	0.004	0.996	0.000
H10.8 Other conjunctivitis	0.003	0.996	0.000
H10.3 Acute conjunctivitis, unspecified	0.003	0.996	0.000
H50 Other strabismus	0.004	0.996	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.004	0.996	0.000
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.000	0.996	0.003
T47.4 Other laxatives	0.003	0.996	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.003	0.996	0.000
D86.9 Sarcoidosis, unspecified	0.004	0.996	0.000
H11.9 Disorder of conjunctiva, unspecified	0.003	0.996	0.000
H13.3 Ocular pemphigoid	0.003	0.996	0.000
H13.1 Conjunctivitis in infectious and parasitic diseases classified elsewhere	0.003	0.996	0.000
H66 Suppurative and unspecified otitis media	0.000	0.996	0.003
H11.2 Conjunctival scars	0.003	0.996	0.000
H51.2 Internuclear ophthalmoplegia	0.003	0.996	0.000
H52 Disorders of refraction and accommodation	0.004	0.996	0.000
H13.8 Other disorders of conjunctiva in diseases classified elsewhere	0.003	0.996	0.000
H13.2 Conjunctivitis in other diseases classified elsewhere	0.003	0.996	0.000
H13.0 Filarial infection of conjunctiva	0.003	0.996	0.000
T47.0 Histamine H(2)-receptor antagonists	0.003	0.996	0.000
H69.9 Eustachian tube disorder, unspecified	0.000	0.997	0.003
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.003	0.997	0.000
H10.2 Other acute conjunctivitis	0.003	0.997	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.003	0.997	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
T47.7 Emetics	0.003	0.997	0.000
T47.5 Digestants	0.003	0.997	0.000
T47.3 Saline and osmotic laxatives	0.003	0.997	0.000
H46 Optic neuritis	0.003	0.997	0.000
H10.5 Blepharoconjunctivitis	0.003	0.997	0.000
H10.1 Acute atopic conjunctivitis	0.003	0.997	0.000
H51.8 Other specified disorders of binocular movement	0.003	0.997	0.000
T47.6 Antidiarrhoeal drugs	0.003	0.997	0.000
H01 Other inflammation of eyelid	0.003	0.997	0.000
E16.2 Hypoglycaemia, unspecified	0.003	0.997	0.000
H51.1 Convergence insufficiency and excess	0.003	0.997	0.000
H51.0 Palsy of conjugate gaze	0.003	0.997	0.000
H06.3 Other disorders of orbit in diseases classified elsewhere	0.003	0.997	0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.003	0.997	0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.003	0.997	0.000
H34.0 Transient retinal artery occlusion	0.003	0.997	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.003	0.997	0.000
H05.2 Exophthalmic conditions	0.003	0.997	0.000
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.003	0.997	0.000
H58.1 Visual disturbances in diseases classified elsewhere	0.003	0.997	0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.003	0.997	0.000
X62.9 Unspecified place	0.003	0.997	0.000
H51.9 Disorder of binocular movement, unspecified	0.003	0.997	0.000
T36 Poisoning by systemic antibiotics	0.003	0.997	0.000
H10.0 Mucopurulent conjunctivitis	0.003	0.997	0.000
M25.37 Other instability of joint (Ankle and foot)	0.000	0.997	0.003
H11.0 Pterygium	0.003	0.997	0.000
H34.1 Central retinal artery occlusion	0.003	0.997	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.003	0.997	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.003	0.997	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.997	0.003
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.997	0.003
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.997	0.003
H70.0 Acute mastoiditis	0.000	0.997	0.003
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.997	0.003
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.997	0.003
D86.0 Sarcoidosis of lung	0.003	0.997	0.000
H68.0 Eustachian salpingitis	0.000	0.997	0.003
M94.89 Other specified disorders of cartilage (Site unspecified)	0.000	0.997	0.003
T48.6 Antiasthmatics, not elsewhere classified	0.003	0.997	0.000
H50.4 Other and unspecified heterotropia	0.003	0.997	0.000
H70.2 Petrositis	0.000	0.997	0.003
T38.0 Glucocorticoids and synthetic analogues	0.003	0.997	0.000
H70.9 Mastoiditis, unspecified	0.000	0.997	0.003
T38.5 Other oestrogens and progestogens	0.003	0.997	0.000
T49.9 Topical agent, unspecified	0.003	0.997	0.000
T49.8 Other topical agents	0.003	0.997	0.000
T49.7 Dental drugs, topically applied	0.003	0.997	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.003	0.997	0.000
T49.5 Ophthalmological drugs and preparations	0.003	0.997	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.003	0.997	0.000
T49.3 Emollients, demulcents and protectants	0.003	0.997	0.000
T49.2 Local astringents and local detergents	0.003	0.997	0.000
T49.1 Antipruritics	0.003	0.997	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.003	0.997	0.000
H69.0 Patulous Eustachian tube	0.000	0.997	0.003
H68.1 Obstruction of Eustachian tube	0.000	0.997	0.003
T38.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
T39.0 Salicylates	0.003	0.997	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.003	0.997	0.000
T48.4 Expectorants	0.003	0.997	0.000
T48.3 Antitussives	0.003	0.997	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.003	0.997	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.003	0.997	0.000
T48.0 Oxytocic drugs	0.003	0.997	0.000
H70.8 Other mastoiditis and related conditions	0.000	0.997	0.003
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.003	0.997	0.000
T39.4 Antirheumatics, not elsewhere classified	0.003	0.997	0.000
T39.2 Pyrazolone derivatives	0.003	0.997	0.000
T48.5 Anti-common-cold drugs	0.003	0.997	0.000
H10.9 Conjunctivitis, unspecified	0.003	0.997	0.000
H53-H54 Visual disturbances and blindness	0.003	0.997	0.000
H52.2 Astigmatism	0.003	0.997	0.000
T39.1 4-Aminophenol derivatives	0.003	0.997	0.000
H55 Nystagmus and other irregular eye movements	0.003	0.997	0.000
H70.1 Chronic mastoiditis	0.000	0.997	0.003
H50.8 Other specified strabismus	0.003	0.997	0.000
T38.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
T38.7 Androgens and anabolic congeners	0.003	0.997	0.000
T38.4 Oral contraceptives	0.003	0.997	0.000
T38.2 Antithyroid drugs	0.003	0.997	0.000
T41.5 Therapeutic gases	0.003	0.997	0.000
T41.4 Anaesthetic, unspecified	0.003	0.997	0.000
T41.3 Local anaesthetics	0.003	0.997	0.000
T41.1 Intravenous anaesthetics	0.003	0.997	0.000
T41.0 Inhaled anaesthetics	0.003	0.997	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.997	0.003
H66.0 Acute suppurative otitis media	0.000	0.997	0.003
H34.9 Retinal vascular occlusion, unspecified	0.003	0.997	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.997	0.003
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
T41.2 Other and unspecified general anaesthetics	0.003	0.997	0.000
N97 Female infertility	0.000	0.997	0.003
H50.6 Mechanical strabismus	0.003	0.997	0.000
H50.3 Intermittent heterotropia	0.003	0.997	0.000
H52.1 Myopia	0.003	0.997	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.003	0.997	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.003	0.997	0.000
H52.3 Anisometropia and aniseikonia	0.003	0.997	0.000
H73 Other disorders of tympanic membrane	0.000	0.997	0.003
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.997	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.997	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.003	0.997	0.000
T44.0 Anticholinesterase agents	0.003	0.997	0.000
H40-H42 Glaucoma	0.003	0.997	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.003	0.997	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.997	0.003
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.003	0.997	0.000
T37.5 Antiviral drugs	0.003	0.997	0.000
T37.4 Anthelminthics	0.003	0.997	0.000
T37.3 Other antiprotozoal drugs	0.003	0.997	0.000
T37.1 Antimycobacterial drugs	0.003	0.997	0.000
T37.0 Sulphonamides	0.003	0.997	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.003	0.997	0.000
H50.1 Divergent concomitant strabismus	0.003	0.997	0.000
T50.4 Drugs affecting uric acid metabolism	0.003	0.997	0.000
H52.6 Other disorders of refraction	0.003	0.997	0.000
H52.5 Disorders of accommodation	0.003	0.997	0.000
N30.2 Other chronic cystitis	0.003	0.997	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.003	0.997	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.003	0.997	0.000
H34.2 Other retinal artery occlusions	0.003	0.997	0.000
T38.1 Thyroid hormones and substitutes	0.003	0.997	0.000
H57 Other disorders of eye and adnexa	0.003	0.997	0.000
Q85 Phakomatoses, not elsewhere classified	0.000	0.997	0.003
Q85.0 Neurofibromatosis (nonmalignant)	0.000	0.997	0.003
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.003	0.997	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.002	0.997	0.000
H50.9 Strabismus, unspecified	0.003	0.997	0.000
Q85.9 Phakomatosis, unspecified	0.000	0.997	0.003
D86 Sarcoidosis	0.003	0.997	0.000
H01.1 Non-infectious dermatoses of eyelid	0.002	0.997	0.000
H52.4 Presbyopia	0.002	0.997	0.000
M25.8 Other specified joint disorders	0.003	0.997	0.000
N97.1 Female infertility of tubal origin	0.000	0.997	0.003
T36.9 Systemic antibiotic, unspecified	0.002	0.997	0.000
T36.7 Antifungal antibiotics, systemically used	0.002	0.997	0.000
T36.6 Rifamycins	0.002	0.997	0.000
T36.5 Aminoglycosides	0.002	0.997	0.000
T36.3 Macrolides	0.002	0.997	0.000
T36.2 Chloramphenicol group	0.002	0.997	0.000
T50.1 Loop [high-ceiling] diuretics	0.002	0.997	0.000
H01.9 Inflammation of eyelid, unspecified	0.002	0.997	0.000
H50.5 Heterophoria	0.002	0.997	0.000
T50.8 Diagnostic agents	0.002	0.997	0.000
H48.8 Other disorders of optic nerve and visual pathways in diseases classified elsewhere	0.002	0.997	0.000
H48.0 Optic atrophy in diseases classified elsewhere	0.002	0.997	0.000
H66.4 Suppurative otitis media, unspecified	0.000	0.997	0.002
T37.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.997	0.000
T45.0 Antiallergic and antiemetic drugs	0.002	0.997	0.000
T50.7 Analeptics and opioid receptor antagonists	0.002	0.997	0.000
T50.5 Appetite depressants	0.002	0.997	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.002	0.997	0.000
T50.0 Mineralocorticoids and their antagonists	0.002	0.997	0.000
H50.0 Convergent concomitant strabismus	0.003	0.997	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.002	0.997	0.000
J42 Unspecified chronic bronchitis	0.000	0.997	0.003
Q54.9 Hypospadias, unspecified	0.000	0.997	0.003
H01.8 Other specified inflammation of eyelid	0.002	0.997	0.000
N97.0 Female infertility associated with anovulation	0.000	0.997	0.002
H48.1 Retrobulbar neuritis in diseases classified elsewhere	0.002	0.997	0.000
H57.0 Anomalies of pupillary function	0.002	0.997	0.000
T45.4 Iron and its compounds	0.002	0.997	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.002	0.997	0.000
O02 Other abnormal products of conception	0.003	0.997	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.002	0.997	0.000
H52.7 Disorder of refraction, unspecified	0.002	0.997	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.997	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.002	0.997	0.000
T45.8 Other primarily systemic and haematological agents	0.002	0.997	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.997	0.000
T45.6 Fibrinolysis-affecting drugs	0.002	0.997	0.000
T45.5 Anticoagulants	0.002	0.997	0.000
T45.3 Enzymes, not elsewhere classified	0.002	0.997	0.000
R04 Haemorrhage from respiratory passages	0.003	0.997	0.000
T36.8 Other systemic antibiotics	0.002	0.997	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.002	0.997	0.000
Q54 Hypospadias	0.000	0.997	0.002
H50.2 Vertical strabismus	0.002	0.998	0.000
K12.1 Other forms of stomatitis	0.002	0.998	0.000
S02.60 Fracture of mandible (closed)	0.002	0.998	0.000
M25.83 Other specified joint disorders (Forearm)	0.002	0.998	0.000
Q54.0 Hypospadias, balanic	0.000	0.998	0.002
T36.0 Penicillins	0.002	0.998	0.000
M25.86 Other specified joint disorders (Lower leg)	0.002	0.998	0.000
H06.2 Dysthyroid exophthalmos	0.002	0.998	0.000
H66.9 Otitis media, unspecified	0.000	0.998	0.002
T36.4 Tetracyclines	0.002	0.998	0.000
H59.0 Vitreous syndrome following cataract surgery	0.002	0.998	0.000
H69.8 Other specified disorders of Eustachian tube	0.001	0.998	0.002
N97.8 Female infertility of other origin	0.000	0.998	0.002
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
H34.8 Other retinal vascular occlusions	0.002	0.998	0.000
N97.3 Female infertility of cervical origin	0.000	0.998	0.002
N97.2 Female infertility of uterine origin	0.000	0.998	0.002
T46.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
T46.7 Peripheral vasodilators	0.002	0.998	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.000	0.998	0.002
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
O02.0 Blighted ovum and nonhydatidiform mole	0.002	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
H42 Glaucoma in diseases classified elsewhere	0.002	0.998	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.002	0.998	0.000
M25.84 Other specified joint disorders (Hand)	0.002	0.998	0.000
N97.4 Female infertility associated with male factors	0.000	0.998	0.002
H74 Other disorders of middle ear and mastoid	0.002	0.998	0.001
H73.1 Chronic myringitis	0.000	0.998	0.002
H73.0 Acute myringitis	0.000	0.998	0.002
R82.8 Abnormal findings on cytological and histological examination of urine	0.000	0.998	0.002
T43.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Q80-Q89 Other congenital malformations	0.000	0.998	0.002
Q85.1 Tuberous sclerosis	0.000	0.998	0.002
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
T46.1 Calcium-channel blockers	0.002	0.998	0.000
M25.82 Other specified joint disorders (Upper arm)	0.002	0.998	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
M25.88 Other specified joint disorders (Other)	0.002	0.998	0.000
H53.2 Diplopia	0.002	0.998	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.998	0.002
H74.3 Other acquired abnormalities of ear ossicles	0.002	0.998	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.002	0.998	0.000
D86.1 Sarcoidosis of lymph nodes	0.002	0.998	0.000
H54.7 Unspecified visual loss	0.002	0.998	0.000
R04.8 Haemorrhage from other sites in respiratory passages	0.002	0.998	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.002	0.998	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.002	0.998	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.002	0.998	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.002	0.998	0.000
D86.8 Sarcoidosis of other and combined sites	0.002	0.998	0.000
T43.9 Psychotropic drug, unspecified	0.002	0.998	0.000
H47.1 Papilloedema, unspecified	0.002	0.998	0.000
T43.2 Other and unspecified antidepressants	0.002	0.998	0.000
H00 Hordeolum and chalazion	0.002	0.998	0.000
H47.5 Disorders of other visual pathways	0.002	0.998	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
H57.8 Other specified disorders of eye and adnexa	0.002	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
H54 Blindness and low vision	0.002	0.998	0.000
M94 Other disorders of cartilage	0.000	0.998	0.002
Q89 Other congenital malformations, not elsewhere classified	0.000	0.998	0.002
Q50-Q56 Congenital malformations of genital organs	0.000	0.998	0.002
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.998	0.000
H47.7 Disorder of visual pathways, unspecified	0.002	0.998	0.000
H47.6 Disorders of visual cortex	0.002	0.998	0.000
H47.4 Disorders of optic chiasm	0.002	0.998	0.000
O02.8 Other specified abnormal products of conception	0.002	0.998	0.000
R04.1 Haemorrhage from throat	0.002	0.998	0.000
T43.6 Psychostimulants with abuse potential	0.002	0.998	0.000
T45.2 Vitamins, not elsewhere classified	0.002	0.998	0.001
H59.8 Other postprocedural disorders of eye and adnexa	0.002	0.998	0.000
H74.1 Adhesive middle ear disease	0.002	0.998	0.000
R04.9 Haemorrhage from respiratory passages, unspecified	0.002	0.998	0.000
R45.1 Restlessness and agitation	0.000	0.998	0.002
I83 Varicose veins of lower extremities	0.000	0.998	0.002
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.002	0.998	0.000
H66.3 Other chronic suppurative otitis media	0.000	0.998	0.002
Q54.4 Congenital chordee	0.000	0.998	0.002
Q54.3 Hypospadias, perineal	0.000	0.998	0.002
Q54.2 Hypospadias, penoscrotal	0.000	0.998	0.002
G56 Mononeuropathies of upper limb	0.000	0.998	0.002
G51.0 Bell's palsy	0.000	0.998	0.002
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.998	0.002
Q54.1 Hypospadias, penile	0.000	0.998	0.002
Q89.2 Congenital malformations of other endocrine glands	0.000	0.998	0.002
E16 Other disorders of pancreatic internal secretion	0.002	0.998	0.000
G56.1 Other lesions of median nerve	0.000	0.998	0.002
Q54.8 Other hypospadias	0.000	0.998	0.002
H25-H28 Disorders of lens	0.002	0.998	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
X62.8 Other specified place	0.002	0.998	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.002	0.998	0.000
R20.2 Paraesthesia of skin	0.002	0.998	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.002	0.998	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.002	0.998	0.000
H74.0 Tympanosclerosis	0.002	0.998	0.000
Q55.6 Other congenital malformations of penis	0.000	0.998	0.002
Q55 Other congenital malformations of male genital organs	0.000	0.998	0.002
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.002	0.998	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.001	0.998	0.001
O02.9 Abnormal product of conception, unspecified	0.002	0.998	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.000	0.998	0.002
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.000	0.998	0.002
Q84 Other congenital malformations of integument	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations