TreeWAS – Variant ID: rs3747517

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.995	0.005	0.000
E03 Other hypothyroidism	0.477	0.523	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.378	0.622	0.000
E03.1 Congenital hypothyroidism without goitre	0.365	0.635	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.348	0.652	0.000
E03.5 Myxoedema coma	0.342	0.658	0.000
E03.4 Atrophy of thyroid (acquired)	0.342	0.658	0.000
E03.3 Postinfectious hypothyroidism	0.342	0.658	0.000
E03.8 Other specified hypothyroidism	0.280	0.720	0.000
E00-E07 Disorders of thyroid gland	0.040	0.960	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.029	0.970	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.028	0.971	0.000
E00 Congenital iodine-deficiency syndrome	0.028	0.971	0.000
E07 Other disorders of thyroid	0.028	0.972	0.000
E06 Thyroiditis	0.026	0.974	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.975	0.025
I60 Subarachnoid haemorrhage	0.000	0.977	0.023
N35.9 Urethral stricture, unspecified	0.022	0.978	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.978	0.022
E06.9 Thyroiditis, unspecified	0.021	0.979	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.021	0.979	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.021	0.979	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.021	0.979	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.021	0.979	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.021	0.979	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.021	0.979	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.021	0.979	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.021	0.979	0.000
E07.9 Disorder of thyroid, unspecified	0.021	0.979	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.980	0.020
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.980	0.020
E07.1 Dyshormogenetic goitre	0.020	0.980	0.000
E07.0 Hypersecretion of calcitonin	0.020	0.980	0.000
E06.4 Drug-induced thyroiditis	0.019	0.981	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.019	0.981	0.000
E06.0 Acute thyroiditis	0.019	0.981	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.981	0.019
E06.3 Autoimmune thyroiditis	0.018	0.981	0.000
E07.8 Other specified disorders of thyroid	0.018	0.982	0.000
E06.1 Subacute thyroiditis	0.018	0.982	0.000
E06.5 Other chronic thyroiditis	0.017	0.983	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.983	0.017
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.983	0.017
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.984	0.016
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.986	0.013
I60.8 Other subarachnoid haemorrhage	0.000	0.987	0.013
N35 Urethral stricture	0.012	0.988	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.988	0.012
E05 Thyrotoxicosis [hyperthyroidism]	0.011	0.989	0.000
M50.1 Cervical disk disorder with radiculopathy	0.010	0.990	0.000
N35.8 Other urethral stricture	0.010	0.990	0.000
E04 Other non-toxic goitre	0.009	0.991	0.000
N35.0 Posttraumatic urethral stricture	0.009	0.991	0.000
N35.1 Postinfective urethral stricture, not elsewhere classified	0.009	0.991	0.000
K27 Peptic ulcer, site unspecified	0.000	0.991	0.009
E05.8 Other thyrotoxicosis	0.008	0.991	0.000
E04.0 Non-toxic diffuse goitre	0.008	0.992	0.000
E05.5 Thyroid crisis or storm	0.008	0.992	0.000
E05.4 Thyrotoxicosis factitia	0.008	0.992	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.008	0.992	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.008	0.992	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.008	0.992	0.000
K70.3 Alcoholic cirrhosis of liver	0.008	0.992	0.000
K27.7 Chronic without haemorrhage or perforation	0.000	0.992	0.008
K56.5 Intestinal adhesions [bands] with obstruction	0.000	0.993	0.007
E04.8 Other specified non-toxic goitre	0.007	0.993	0.000
K27.3 Acute without haemorrhage or perforation	0.000	0.993	0.007
K27.4 Chronic or unspecified with haemorrhage	0.000	0.993	0.007
K27.0 Acute with haemorrhage	0.000	0.993	0.007
K70.9 Alcoholic liver disease, unspecified	0.007	0.993	0.000
K70 Alcoholic liver disease	0.007	0.993	0.000
K27.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.994	0.006
K27.5 Chronic or unspecified with perforation	0.000	0.994	0.006
K27.2 Acute with both haemorrhage and perforation	0.000	0.994	0.006
K27.1 Acute with perforation	0.000	0.994	0.006
L71.9 Rosacea, unspecified	0.006	0.994	0.000
E04.9 Non-toxic goitre, unspecified	0.006	0.994	0.000
S82.20 Fracture of shaft of tibia (closed)	0.006	0.994	0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.006	0.994	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.005	0.995	0.000
F10.2 Dependence syndrome	0.005	0.995	0.000
K70.4 Alcoholic hepatic failure	0.005	0.995	0.000
K70.1 Alcoholic hepatitis	0.005	0.995	0.000
O82.0 Delivery by elective Caesarean section	0.005	0.995	0.000
R12 Heartburn	0.000	0.995	0.005
H72.0 Central perforation of tympanic membrane	0.005	0.995	0.000
C45.9 Mesothelioma, unspecified	0.000	0.995	0.005
Z29.2 Other prophylactic chemotherapy	0.000	0.995	0.005
C44.2 Skin of ear and external auricular canal	0.000	0.996	0.004
H65.4 Other chronic nonsuppurative otitis media	0.004	0.996	0.000
K70.0 Alcoholic fatty liver	0.004	0.996	0.000
H65 Nonsuppurative otitis media	0.004	0.996	0.000
D47.1 Chronic myeloproliferative disease	0.000	0.996	0.004
L43.8 Other lichen planus	0.004	0.996	0.000
O82 Single delivery by Caesarean section	0.004	0.996	0.000
H65.2 Chronic serous otitis media	0.004	0.996	0.000
C45 Mesothelioma	0.000	0.996	0.004
E05.9 Thyrotoxicosis, unspecified	0.004	0.996	0.000
O82.9 Delivery by Caesarean section, unspecified	0.004	0.996	0.000
H72 Perforation of tympanic membrane	0.004	0.996	0.000
C45.7 Mesothelioma of other sites	0.000	0.996	0.004
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.004	0.996	0.000
C45.0 Mesothelioma of pleura	0.000	0.996	0.004
H65.3 Chronic mucoid otitis media	0.004	0.996	0.000
I49.8 Other specified cardiac arrhythmias	0.000	0.996	0.004
L43.9 Lichen planus, unspecified	0.004	0.996	0.000
H72.2 Other marginal perforations of tympanic membrane	0.003	0.997	0.000
O61.0 Failed medical induction of labour	0.003	0.997	0.000
H65-H75 Diseases of middle ear and mastoid	0.003	0.997	0.000
Q63.0 Accessory kidney	0.003	0.997	0.000
F01.9 Vascular dementia, unspecified	0.003	0.997	0.000
H65.0 Acute serous otitis media	0.003	0.997	0.000
H70 Mastoiditis and related conditions	0.003	0.997	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.003	0.997	0.000
F41.2 Mixed anxiety and depressive disorder	0.003	0.997	0.000
O82.1 Delivery by emergency Caesarean section	0.003	0.997	0.000
Z89.5 Acquired absence of leg at or below knee	0.003	0.997	0.000
L71 Rosacea	0.003	0.997	0.000
Q63 Other congenital malformations of kidney	0.003	0.997	0.000
Z29 Need for other prophylactic measures	0.000	0.997	0.003
H70.9 Mastoiditis, unspecified	0.003	0.997	0.000
L43 Lichen planus	0.003	0.997	0.000
O82.8 Other single delivery by Caesarean section	0.003	0.997	0.000
O82.2 Delivery by Caesarean hysterectomy	0.003	0.997	0.000
H65.1 Other acute nonsuppurative otitis media	0.003	0.997	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.003	0.997	0.000
C45.2 Mesothelioma of pericardium	0.000	0.997	0.003
C45.1 Mesothelioma of peritoneum	0.000	0.997	0.003
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997	0.000
Z29.1 Prophylactic immunotherapy	0.000	0.997	0.003
L71.8 Other rosacea	0.003	0.997	0.000
H70.0 Acute mastoiditis	0.003	0.997	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.003	0.997	0.000
H21.0 Hyphaema	0.000	0.997	0.003
Z29.8 Other specified prophylactic measures	0.000	0.997	0.003
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.997	0.003
Z89.4 Acquired absence of foot and ankle	0.003	0.997	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.997	0.003
M89.87 Other specified disorders of bone (Ankle and foot)	0.003	0.997	0.000
H68 Eustachian salpingitis and obstruction	0.003	0.997	0.000
H70.8 Other mastoiditis and related conditions	0.003	0.997	0.000
Q63.2 Ectopic kidney	0.003	0.997	0.000
H90.0 Conductive hearing loss, bilateral	0.003	0.997	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.003	0.997	0.000
H69 Other disorders of Eustachian tube	0.003	0.997	0.000
H67 Otitis media in diseases classified elsewhere	0.003	0.997	0.000
H74 Other disorders of middle ear and mastoid	0.003	0.997	0.000
H70.2 Petrositis	0.002	0.997	0.000
Z89.6 Acquired absence of leg above knee	0.003	0.997	0.000
I46.0 Cardiac arrest with successful resuscitation	0.000	0.997	0.003
H71 Cholesteatoma of middle ear	0.003	0.997	0.000
L71.0 Perioral dermatitis	0.002	0.997	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.002	0.997	0.000
Q63.3 Hyperplastic and giant kidney	0.002	0.997	0.000
Z29.9 Prophylactic measure, unspecified	0.000	0.997	0.002
L43.3 Subacute (active) lichen planus	0.002	0.997	0.000
L43.2 Lichenoid drug reaction	0.002	0.997	0.000
L43.1 Bullous lichen planus	0.002	0.997	0.000
Q63.8 Other specified congenital malformations of kidney	0.002	0.997	0.000
H21.8 Other specified disorders of iris and ciliary body	0.000	0.997	0.002
K02.9 Dental caries, unspecified	0.002	0.998	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.000	0.998	0.002
S82.2 Fracture of shaft of tibia	0.002	0.998	0.000
H66 Suppurative and unspecified otitis media	0.002	0.998	0.000
N83.1 Corpus luteum cyst	0.002	0.998	0.000
Z89 Acquired absence of limb	0.002	0.998	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.002	0.998	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.002	0.998	0.000
L43.0 Hypertrophic lichen planus	0.002	0.998	0.000
L71.1 Rhinophyma	0.002	0.998	0.000
T91.3 Sequelae of injury of spinal cord	0.002	0.998	0.000
C54.9 Corpus uteri, unspecified	0.000	0.998	0.002
H18.8 Other specified disorders of cornea	0.000	0.998	0.002
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.000	0.998	0.002
H69.8 Other specified disorders of Eustachian tube	0.002	0.998	0.000
H68.1 Obstruction of Eustachian tube	0.002	0.998	0.000
C53.9 Cervix uteri, unspecified	0.000	0.998	0.002
H74.2 Discontinuity and dislocation of ear ossicles	0.002	0.998	0.000
I49.9 Cardiac arrhythmia, unspecified	0.000	0.998	0.002
H21 Other disorders of iris and ciliary body	0.000	0.998	0.002
H68.0 Eustachian salpingitis	0.002	0.998	0.000
H70.1 Chronic mastoiditis	0.002	0.998	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.002	0.998	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.002	0.998	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.002	0.998	0.000
H69.0 Patulous Eustachian tube	0.002	0.998	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.002	0.998	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
G71.0 Muscular dystrophy	0.002	0.998	0.000
H66.3 Other chronic suppurative otitis media	0.002	0.998	0.000
Z89.9 Acquired absence of limb, unspecified	0.002	0.998	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.998	0.000
H72.1 Attic perforation of tympanic membrane	0.002	0.998	0.000
H73 Other disorders of tympanic membrane	0.002	0.998	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.002	0.998	0.000
K56.4 Other impaction of intestine	0.000	0.998	0.002
H66.1 Chronic tubotympanic suppurative otitis media	0.002	0.998	0.000
H69.9 Eustachian tube disorder, unspecified	0.002	0.998	0.000
C53 Malignant neoplasm of cervix uteri	0.000	0.998	0.002
H01.8 Other specified inflammation of eyelid	0.000	0.998	0.002
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.002	0.998	0.000
C54 Malignant neoplasm of corpus uteri	0.000	0.998	0.002
C53.0 Endocervix	0.000	0.998	0.002
H66.0 Acute suppurative otitis media	0.002	0.998	0.000
H74.1 Adhesive middle ear disease	0.002	0.998	0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.002	0.998	0.000
Q51.3 Bicornate uterus	0.002	0.998	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.002	0.998	0.000
H21.2 Degeneration of iris and ciliary body	0.000	0.998	0.002
Q51.2 Other doubling of uterus	0.002	0.998	0.000
Z89.3 Acquired absence of both upper limbs [any level]	0.002	0.998	0.000
Z89.1 Acquired absence of hand and wrist	0.002	0.998	0.000
F01 Vascular dementia	0.002	0.998	0.000
Q64 Other congenital malformations of urinary system	0.002	0.998	0.000
S22.20 Fracture of sternum (closed)	0.002	0.998	0.000
Q60-Q64 Congenital malformations of the urinary system	0.002	0.998	0.000
H21.4 Pupillary membranes	0.000	0.998	0.002
H66.4 Suppurative otitis media, unspecified	0.002	0.998	0.000
H72.8 Other perforations of tympanic membrane	0.002	0.998	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.998	0.002
E05.0 Thyrotoxicosis with diffuse goitre	0.002	0.998	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.000	0.998	0.002
C54.1 Endometrium	0.000	0.998	0.002
H21.9 Disorder of iris and ciliary body, unspecified	0.000	0.998	0.002
H66.2 Chronic atticoantral suppurative otitis media	0.002	0.998	0.000
Q51 Congenital malformations of uterus and cervix	0.002	0.998	0.000
Q64.4 Malformation of urachus	0.002	0.998	0.000
G93.6 Cerebral oedema	0.000	0.998	0.002
H73.0 Acute myringitis	0.002	0.998	0.000
I49.0 Ventricular fibrillation and flutter	0.000	0.998	0.002
H74.0 Tympanosclerosis	0.002	0.998	0.000
Q50.5 Embryonic cyst of broad ligament	0.002	0.998	0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.000	0.998	0.002
H73.1 Chronic myringitis	0.002	0.998	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.002	0.998	0.000
Q50.3 Other congenital malformations of ovary	0.002	0.998	0.000
Q50.2 Congenital torsion of ovary	0.002	0.998	0.000
Q50.1 Developmental ovarian cyst	0.002	0.998	0.000
Q50.0 Congenital absence of ovary	0.002	0.998	0.000
Z26.9 Need for immunisation against unspecified infectious disease	0.000	0.998	0.002
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.998	0.002
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.002	0.998	0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.000	0.998	0.002
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.002	0.998	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.002	0.998	0.000
S82.21 Fracture of shaft of tibia (open)	0.002	0.998	0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.002	0.998	0.000
C25.0 Head of pancreas	0.000	0.998	0.002
M23.5 Chronic instability of knee	0.000	0.998	0.002
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.002	0.998	0.000
C53.8 Overlapping lesion of cervix uteri	0.000	0.998	0.002
C53.1 Exocervix	0.000	0.998	0.002
C54.8 Overlapping lesion of corpus uteri	0.000	0.998	0.002
C54.3 Fundus uteri	0.000	0.998	0.002
C54.2 Myometrium	0.000	0.998	0.002
C54.0 Isthmus uteri	0.000	0.998	0.002
H73.9 Disorder of tympanic membrane, unspecified	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.998	0.002
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.002	0.998	0.000
Z26 Need for immunisation against other single infectious diseases	0.000	0.998	0.002
M89.8 Other specified disorders of bone	0.002	0.998	0.000
F01.8 Other vascular dementia	0.002	0.998	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.002	0.998	0.000
F01.2 Subcortical vascular dementia	0.002	0.998	0.000
F01.0 Vascular dementia of acute onset	0.002	0.998	0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.002	0.998	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.002	0.998	0.000
Q64.8 Other specified congenital malformations of urinary system	0.002	0.998	0.000
Q64.6 Congenital diverticulum of bladder	0.002	0.998	0.000
Q64.5 Congenital absence of bladder and urethra	0.002	0.998	0.000
Q64.2 Congenital posterior urethral valves	0.002	0.998	0.000
Q64.1 Exstrophy of urinary bladder	0.002	0.998	0.000
Q64.0 Epispadias	0.002	0.998	0.000
Z89.8 Acquired absence of upper and lower limbs [any level]	0.001	0.998	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.002	0.998	0.000
C92.0 Acute myeloid leukaemia	0.000	0.998	0.002
N62 Hypertrophy of breast	0.002	0.998	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.002	0.998	0.000
H74.4 Polyp of middle ear	0.002	0.998	0.000
W20.0 Home	0.002	0.998	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.000	0.998	0.002
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.998	0.002
M89.84 Other specified disorders of bone (Hand)	0.002	0.998	0.000
S89.9 Unspecified injury of lower leg	0.002	0.998	0.000
C62.9 Testis, unspecified	0.000	0.998	0.002
F01.1 Multi-infarct dementia	0.002	0.998	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.000	0.998	0.001
Q51.8 Other congenital malformations of uterus and cervix	0.002	0.998	0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.001	0.998	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.001	0.998	0.000
Q51.6 Embryonic cyst of cervix	0.001	0.998	0.000
Q51.5 Agenesis and aplasia of cervix	0.001	0.998	0.000
Q51.0 Agenesis and aplasia of uterus	0.001	0.998	0.000
Q60.3 Renal hypoplasia, unilateral	0.002	0.998	0.000
Q62.1 Atresia and stenosis of ureter	0.002	0.998	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.998	0.002
D45 Polycythaemia vera	0.000	0.998	0.002
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.002
Z29.0 Isolation	0.000	0.998	0.002
H17.9 Corneal scar and opacity, unspecified	0.000	0.998	0.002
H21.5 Other adhesions and disruptions of iris and ciliary body	0.000	0.998	0.001
Q51.4 Unicornate uterus	0.001	0.998	0.000
V93.9 Unspecified watercraft	0.000	0.998	0.002
D06.9 Cervix, unspecified	0.000	0.998	0.002
H20.0 Acute and subacute iridocyclitis	0.000	0.998	0.002
M84.1 Nonunion of fracture [pseudarthrosis]	0.002	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.998	0.001
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
D35.1 Parathyroid gland	0.002	0.998	0.000
E04.1 Non-toxic single thyroid nodule	0.001	0.998	0.000
H18.9 Disorder of cornea, unspecified	0.000	0.998	0.002
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.998	0.001
C51-C58 Malignant neoplasms of female genital organs	0.000	0.998	0.002
Q50-Q56 Congenital malformations of genital organs	0.002	0.998	0.000
E61.1 Iron deficiency	0.000	0.998	0.002
G71.1 Myotonic disorders	0.002	0.998	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.998	0.001
Z89.2 Acquired absence of upper limb above wrist	0.001	0.998	0.000
M23.57 Chronic instability of knee (Capsular ligament)	0.000	0.998	0.001
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.000	0.998	0.001
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.000	0.998	0.001
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.998	0.001
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.998	0.001
M89.89 Other specified disorders of bone (Site unspecified)	0.001	0.998	0.000
Q62.8 Other congenital malformations of ureter	0.001	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.998	0.001
T46.7 Peripheral vasodilators	0.000	0.998	0.001
Z26.8 Need for immunisation against other specified single infectious diseases	0.000	0.998	0.001
Z26.0 Need for immunisation against leishmaniasis	0.000	0.998	0.001
F03 Unspecified dementia	0.002	0.998	0.000
G71 Primary disorders of muscles	0.002	0.998	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.001	0.998	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.001	0.998	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.001	0.998	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.001	0.998	0.000
M23.50 Chronic instability of knee (Multiple sites)	0.000	0.998	0.001
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.001	0.998	0.000
Q60.6 Potter's syndrome	0.001	0.998	0.000
Q60.5 Renal hypoplasia, unspecified	0.001	0.998	0.000
Q60.4 Renal hypoplasia, bilateral	0.001	0.998	0.000
Q60.1 Renal agenesis, bilateral	0.001	0.998	0.000
H16.0 Corneal ulcer	0.000	0.998	0.001
H18.0 Corneal pigmentations and deposits	0.000	0.998	0.001
N97.9 Female infertility, unspecified	0.002	0.998	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.001	0.998	0.000
Q62.6 Malposition of ureter	0.001	0.998	0.000
Q62.4 Agenesis of ureter	0.001	0.998	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.001	0.998	0.000
Q62.0 Congenital hydronephrosis	0.001	0.998	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.998	0.001
T91.1 Sequelae of fracture of spine	0.001	0.998	0.000
H17 Corneal scars and opacities	0.000	0.998	0.001
O61 Failed induction of labour	0.001	0.998	0.000
Z28 Immunisation not carried out	0.000	0.998	0.001
Z27 Need for immunisation against combinations of infectious diseases	0.000	0.998	0.001
Z25 Need for immunisation against other single viral diseases	0.000	0.998	0.001
Z23 Need for immunisation against single bacterial diseases	0.000	0.998	0.001
Q60.2 Renal agenesis, unspecified	0.001	0.999	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.000	0.999	0.001
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.999	0.001
T46.1 Calcium-channel blockers	0.000	0.999	0.001
C57 Malignant neoplasm of other and unspecified female genital organs	0.000	0.999	0.001
M13.99 Arthritis, unspecified (Site unspecified)	0.001	0.999	0.000
M89.88 Other specified disorders of bone (Other)	0.001	0.999	0.000
N28.8 Other specified disorders of kidney and ureter	0.001	0.999	0.000
R85.8 Other abnormal findings	0.000	0.999	0.001
T47.0 Histamine H(2)-receptor antagonists	0.000	0.999	0.001
I49 Other cardiac arrhythmias	0.000	0.999	0.001
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.000	0.999	0.001
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.001	0.999	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.001	0.999	0.000
C57.9 Female genital organ, unspecified	0.000	0.999	0.001
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.999	0.001
C52 Malignant neoplasm of vagina	0.000	0.999	0.001
Q53 Undescended testicle	0.001	0.999	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.001	0.999	0.000
D37.4 Colon	0.000	0.999	0.001
H18.3 Changes in corneal membranes	0.000	0.999	0.001
O61.9 Failed induction of labour, unspecified	0.001	0.999	0.000
Q83.8 Other congenital malformations of breast	0.001	0.999	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.000	0.999	0.001
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.000	0.999	0.001
C58 Malignant neoplasm of placenta	0.000	0.999	0.001
Q56 Indeterminate sex and pseudohermaphroditism	0.001	0.999	0.000
Q52 Other congenital malformations of female genitalia	0.001	0.999	0.000
Z24 Need for immunisation against certain single viral diseases	0.000	0.999	0.001
M89.83 Other specified disorders of bone (Forearm)	0.001	0.999	0.000
G71.3 Mitochondrial myopathy, not elsewhere classified	0.001	0.999	0.000
H66.9 Otitis media, unspecified	0.001	0.999	0.000
Q53.1 Undescended testicle, unilateral	0.001	0.999	0.000
Q62.5 Duplication of ureter	0.001	0.999	0.000
Q83 Congenital malformations of breast	0.001	0.999	0.000
T91 Sequelae of injuries of neck and trunk	0.001	0.999	0.000
Z20 Contact with and exposure to communicable diseases	0.000	0.999	0.001
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.001	0.999	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.000	0.999	0.001
Q83.1 Accessory breast	0.001	0.999	0.000
G71.9 Primary disorder of muscle, unspecified	0.001	0.999	0.000
G71.8 Other primary disorders of muscles	0.001	0.999	0.000
G71.2 Congenital myopathies	0.001	0.999	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.001	0.999	0.000
Q60.0 Renal agenesis, unilateral	0.001	0.999	0.000
Q62.2 Congenital megaloureter	0.001	0.999	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.001	0.999	0.000
C51 Malignant neoplasm of vulva	0.000	0.999	0.001
H18 Other disorders of cornea	0.000	0.999	0.001
C57.0 Fallopian tube	0.000	0.999	0.001
H43.8 Other disorders of vitreous body	0.000	0.999	0.001
O44.0 Placenta praevia specified as without haemorrhage	0.000	0.999	0.001
O61.8 Other failed induction of labour	0.001	0.999	0.000
Z23.8 Need for immunisation against other single bacterial diseases	0.000	0.999	0.001
Z23.7 Need for immunisation against pertussis alone	0.000	0.999	0.001
Z23.6 Need for immunisation against diphtheria alone	0.000	0.999	0.001
Z23.5 Need for immunisation against tetanus alone	0.000	0.999	0.001
Z23.4 Need for immunisation against tularaemia	0.000	0.999	0.001
Z23.3 Need for immunisation against plague	0.000	0.999	0.001
Z23.2 Need for immunisation against tuberculosis [BCG]	0.000	0.999	0.001
Z23.1 Need for immunisation against typhoid-paratyphoid alone [TAB]	0.000	0.999	0.001
Z23.0 Need for immunisation against cholera alone	0.000	0.999	0.001
Z25.8 Need for immunisation against other specified single viral diseases	0.000	0.999	0.001
Z25.1 Need for immunisation against influenza	0.000	0.999	0.001
Z25.0 Need for immunisation against mumps alone	0.000	0.999	0.001
Z27.9 Need for immunisation against unspecified combinations of infectious diseases	0.000	0.999	0.001
Z27.8 Need for immunisation against other combinations of infectious diseases	0.000	0.999	0.001
Z27.4 Need for immunisation against measles-mumps-rubella [MMR]	0.000	0.999	0.001
Z27.3 Need for immunisation against diphtheria-tetanus-pertussis with poliomyelitis [DTP + polio]	0.000	0.999	0.001
Z27.2 Need for immunisation against diphtheria-tetanus-pertussis with typhoid-paratyphoid [DTP + TAB]	0.000	0.999	0.001
Z27.1 Need for immunisation against diphtheria-tetanus-pertussis, combined [DTP]	0.000	0.999	0.001
Z27.0 Need for immunisation against cholera with typhoid-paratyphoid [cholera + TAB]	0.000	0.999	0.001
Z28.9 Immunisation not carried out for unspecified reason	0.000	0.999	0.001
Z28.8 Immunisation not carried out for other reasons	0.000	0.999	0.001
Z28.2 Immunisation not carried out because of patient's decision for other and unspecified reasons	0.000	0.999	0.001
Z28.1 Immunisation not carried out because of patient's decision for reasons of belief or group pressure	0.000	0.999	0.001
Z28.0 Immunisation not carried out because of contraindication	0.000	0.999	0.001
M89.86 Other specified disorders of bone (Lower leg)	0.001	0.999	0.000
C51.9 Vulva, unspecified	0.000	0.999	0.001
H17.1 Other central corneal opacity	0.000	0.999	0.001
H17.0 Adherent leukoma	0.000	0.999	0.001
Q82.8 Other specified congenital malformations of skin	0.001	0.999	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.001	0.999	0.000
R85.5 Abnormal microbiological findings	0.000	0.999	0.001
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.999	0.001
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.999	0.001
M13.94 Arthritis, unspecified (Hand)	0.001	0.999	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.001	0.999	0.000
C57.7 Other specified female genital organs	0.000	0.999	0.001
C57.4 Uterine adnexa, unspecified	0.000	0.999	0.001
C57.3 Parametrium	0.000	0.999	0.001
C57.2 Round ligament	0.000	0.999	0.001
C57.1 Broad ligament	0.000	0.999	0.001
G31.2 Degeneration of nervous system due to alcohol	0.001	0.999	0.000
I49.2 Junctional premature depolarisation	0.000	0.999	0.001
O41.8 Other specified disorders of amniotic fluid and membranes	0.001	0.999	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.001	0.999	0.000
Y84.1 Kidney dialysis	0.000	0.999	0.001
Z20.9 Contact with and exposure to unspecified communicable disease	0.000	0.999	0.001
H20 Iridocyclitis	0.000	0.999	0.001
H16 Keratitis	0.000	0.999	0.001
Q55 Other congenital malformations of male genital organs	0.001	0.999	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
I27.8 Other specified pulmonary heart diseases	0.001	0.999	0.000
O14.0 Moderate preeclampsia	0.001	0.999	0.000
Q83.3 Accessory nipple	0.001	0.999	0.000
T36.3 Macrolides	0.000	0.999	0.001
T42.1 Iminostilbenes	0.000	0.999	0.001
Q52.9 Congenital malformation of female genitalia, unspecified	0.001	0.999	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.001	0.999	0.000
Q52.7 Other congenital malformations of vulva	0.001	0.999	0.000
Q52.6 Congenital malformation of clitoris	0.001	0.999	0.000
Q52.5 Fusion of labia	0.001	0.999	0.000
Q52.4 Other congenital malformations of vagina	0.001	0.999	0.000
Q52.3 Imperforate hymen	0.001	0.999	0.000
Q52.2 Congenital rectovaginal fistula	0.001	0.999	0.000
Q52.0 Congenital absence of vagina	0.001	0.999	0.000
Q53.0 Ectopic testis	0.001	0.999	0.000
Q56.4 Indeterminate sex, unspecified	0.001	0.999	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.001	0.999	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.001	0.999	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.001	0.999	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.001	0.999	0.000
Z24.6 Need for immunisation against viral hepatitis	0.000	0.999	0.001
Z24.4 Need for immunisation against measles alone	0.000	0.999	0.001
Z24.3 Need for immunisation against yellow fever	0.000	0.999	0.001
Z24.2 Need for immunisation against rabies	0.000	0.999	0.001
Z24.1 Need for immunisation against arthropod-borne viral encephalitis	0.000	0.999	0.001
Z24.0 Need for immunisation against poliomyelitis	0.000	0.999	0.001
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.000	0.999	0.001
M13.96 Arthritis, unspecified (Lower leg)	0.001	0.999	0.000
Q83.9 Congenital malformation of breast, unspecified	0.001	0.999	0.000
Q83.2 Absent nipple	0.001	0.999	0.000
Q83.0 Congenital absence of breast with absent nipple	0.001	0.999	0.000
T47.4 Other laxatives	0.000	0.999	0.001
T82.4 Mechanical complication of vascular dialysis catheter	0.000	0.999	0.001
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.001	0.999	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.001	0.999	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.001	0.999	0.000
Z20.7 Contact with and exposure to pediculosis, acariasis and other infestations	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations