TreeWAS – Variant ID: rs3775182

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D69.6 Thrombocytopenia, unspecified	0.065	0.935	0.000
D69 Purpura and other haemorrhagic conditions	0.057	0.943	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.052	0.948	0.000
D69.9 Haemorrhagic condition, unspecified	0.044	0.956	0.000
D69.0 Allergic purpura	0.044	0.956	0.000
D69.2 Other nonthrombocytopenic purpura	0.043	0.957	0.000
D69.8 Other specified haemorrhagic conditions	0.041	0.959	0.000
D69.4 Other primary thrombocytopenia	0.041	0.959	0.000
D69.1 Qualitative platelet defects	0.041	0.959	0.000
D69.5 Secondary thrombocytopenia	0.038	0.961	0.000
K01.1 Impacted teeth	0.000	0.970	0.030
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.020	0.980	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.015	0.985	0.000
D67 Hereditary factor IX deficiency	0.014	0.985	0.000
K01 Embedded and impacted teeth	0.000	0.986	0.013
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.013	0.987	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.013	0.987	0.000
D60-D64 Aplastic and other anaemias	0.012	0.988	0.000
D50-D53 Nutritional anaemias	0.012	0.988	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.012	0.988	0.000
D61 Other aplastic anaemias	0.012	0.988	0.000
D50.8 Other iron deficiency anaemias	0.012	0.988	0.000
D63.0 Anaemia in neoplastic disease	0.011	0.989	0.000
D50 Iron deficiency anaemia	0.011	0.989	0.000
D61.9 Aplastic anaemia, unspecified	0.011	0.989	0.000
D66 Hereditary factor VIII deficiency	0.010	0.989	0.000
K01.0 Embedded teeth	0.000	0.990	0.010
D52 Folate deficiency anaemia	0.010	0.990	0.000
D55-D59 Haemolytic anaemias	0.010	0.990	0.000
D12.2 Ascending colon	0.000	0.990	0.010
D80-D89 Certain disorders involving the immune mechanism	0.010	0.990	0.000
D61.1 Drug-induced aplastic anaemia	0.010	0.990	0.000
D53 Other nutritional anaemias	0.009	0.990	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.009	0.991	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.009	0.991	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.009	0.991	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.009	0.991	0.000
D52.9 Folate deficiency anaemia, unspecified	0.009	0.991	0.000
D61.8 Other specified aplastic anaemias	0.009	0.991	0.000
D61.3 Idiopathic aplastic anaemia	0.009	0.991	0.000
D61.2 Aplastic anaemia due to other external agents	0.009	0.991	0.000
D61.0 Constitutional aplastic anaemia	0.009	0.991	0.000
L72.0 Epidermal cyst	0.000	0.991	0.009
D89.9 Disorder involving the immune mechanism, unspecified	0.008	0.992	0.000
D50.1 Sideropenic dysphagia	0.008	0.992	0.000
S42.00 Fracture of clavicle (closed)	0.000	0.992	0.008
D59 Acquired haemolytic anaemia	0.008	0.992	0.000
D53.9 Nutritional anaemia, unspecified	0.008	0.992	0.000
D58 Other hereditary haemolytic anaemias	0.008	0.992	0.000
D52.8 Other folate deficiency anaemias	0.007	0.992	0.000
D52.1 Drug-induced folate deficiency anaemia	0.007	0.992	0.000
D52.0 Dietary folate deficiency anaemia	0.007	0.992	0.000
D57 Sickle-cell disorders	0.007	0.992	0.000
D56 Thalassaemia	0.007	0.992	0.000
D55 Anaemia due to enzyme disorders	0.007	0.992	0.000
D83 Common variable immunodeficiency	0.007	0.993	0.000
D82 Immunodeficiency associated with other major defects	0.007	0.993	0.000
D81 Combined immunodeficiencies	0.007	0.993	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.007	0.993	0.000
D84 Other immunodeficiencies	0.007	0.993	0.000
D53.8 Other specified nutritional anaemias	0.007	0.993	0.000
D53.2 Scorbutic anaemia	0.007	0.993	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.007	0.993	0.000
D53.0 Protein deficiency anaemia	0.007	0.993	0.000
D80 Immunodeficiency with predominantly antibody defects	0.007	0.993	0.000
D68 Other coagulation defects	0.007	0.993	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.007	0.993	0.000
D60.8 Other acquired pure red cell aplasias	0.007	0.993	0.000
D60.1 Transient acquired pure red cell aplasia	0.007	0.993	0.000
D60.0 Chronic acquired pure red cell aplasia	0.007	0.993	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.007	0.993	0.000
D89.3 Immune reconstitution syndrome	0.007	0.993	0.000
D89.1 Cryoglobulinaemia	0.007	0.993	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.007	0.993	0.000
L29.9 Pruritus, unspecified	0.006	0.994	0.000
D59.1 Other autoimmune haemolytic anaemias	0.006	0.994	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.006	0.994	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.006	0.994	0.000
S42.0 Fracture of clavicle	0.000	0.994	0.006
D86 Sarcoidosis	0.006	0.994	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.006	0.994	0.000
D59.8 Other acquired haemolytic anaemias	0.006	0.994	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.006	0.994	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.006	0.994	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.006	0.994	0.000
D59.3 Haemolytic-uraemic syndrome	0.006	0.994	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.006	0.994	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.006	0.994	0.000
D22.5 Melanocytic naevi of trunk	0.006	0.994	0.000
D51 Vitamin B12 deficiency anaemia	0.006	0.994	0.000
Y52 Agents primarily affecting the cardiovascular system	0.006	0.994	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.006	0.994	0.000
D58.2 Other haemoglobinopathies	0.006	0.994	0.000
D58.1 Hereditary elliptocytosis	0.006	0.994	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.005	0.994	0.000
D55.8 Other anaemias due to enzyme disorders	0.005	0.994	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.005	0.994	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.005	0.994	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.005	0.994	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.005	0.994	0.000
D56.9 Thalassaemia, unspecified	0.005	0.994	0.000
D56.8 Other thalassaemias	0.005	0.994	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.005	0.994	0.000
D56.3 Thalassaemia trait	0.005	0.994	0.000
D56.2 Delta-beta thalassaemia	0.005	0.994	0.000
D56.1 Beta thalassaemia	0.005	0.994	0.000
D56.0 Alpha thalassaemia	0.005	0.994	0.000
D57.8 Other sickle-cell disorders	0.005	0.994	0.000
D57.3 Sickle-cell trait	0.005	0.994	0.000
D57.2 Double heterozygous sickling disorders	0.005	0.994	0.000
D57.1 Sickle-cell anaemia without crisis	0.005	0.994	0.000
D57.0 Sickle-cell anaemia with crisis	0.005	0.994	0.000
D68.8 Other specified coagulation defects	0.006	0.994	0.000
D81.9 Combined immunodeficiency, unspecified	0.005	0.994	0.000
D81.8 Other combined immunodeficiencies	0.005	0.994	0.000
D81.7 Major histocompatibility complex class II deficiency	0.005	0.994	0.000
D81.6 Major histocompatibility complex class I deficiency	0.005	0.994	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.005	0.994	0.000
D81.4 Nezelof's syndrome	0.005	0.994	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.005	0.994	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.005	0.994	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.005	0.994	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.005	0.994	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.005	0.994	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.005	0.994	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.005	0.994	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.005	0.994	0.000
D82.2 Immunodeficiency with short-limbed stature	0.005	0.994	0.000
D82.1 Di George's syndrome	0.005	0.994	0.000
D82.0 Wiskott-Aldrich syndrome	0.005	0.994	0.000
D83.9 Common variable immunodeficiency, unspecified	0.005	0.994	0.000
D83.8 Other common variable immunodeficiencies	0.005	0.994	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.005	0.994	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.005	0.994	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.005	0.994	0.000
D58.0 Hereditary spherocytosis	0.005	0.994	0.000
D68.6 Other Thrombophilia	0.005	0.994	0.000
D62 Acute posthaemorrhagic anaemia	0.005	0.995	0.000
D84.8 Other specified immunodeficiencies	0.005	0.995	0.000
D84.1 Defects in the complement system	0.005	0.995	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.005	0.995	0.000
D68.4 Acquired coagulation factor deficiency	0.005	0.995	0.000
D68.1 Hereditary factor XI deficiency	0.005	0.995	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.005	0.995	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.005	0.995	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.005	0.995	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.005	0.995	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.005	0.995	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.005	0.995	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.005	0.995	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.005	0.995	0.000
D84.9 Immunodeficiency, unspecified	0.005	0.995	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.005	0.995	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.005	0.995	0.000
D50.9 Iron deficiency anaemia, unspecified	0.005	0.995	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.005	0.995	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.005	0.995	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.005	0.995	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.005	0.995	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.005	0.995	0.000
D86.1 Sarcoidosis of lymph nodes	0.005	0.995	0.000
Y57 Other and unspecified drugs and medicaments	0.005	0.995	0.000
D64 Other anaemias	0.005	0.995	0.000
C18.9 Colon, unspecified	0.000	0.995	0.005
Y44 Agents primarily affecting blood constituents	0.005	0.995	0.000
D86.0 Sarcoidosis of lung	0.005	0.995	0.000
Y53.4 Other laxatives	0.005	0.995	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.005	0.995	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.005	0.995	0.000
Y57.9 Drug or medicament, unspecified	0.005	0.995	0.000
D86.3 Sarcoidosis of skin	0.004	0.995	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.005	0.995	0.000
S42.01 Fracture of clavicle (open)	0.000	0.995	0.004
S42.10 Fracture of scapula (closed)	0.000	0.995	0.005
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.004	0.995	0.000
K70.4 Alcoholic hepatic failure	0.004	0.995	0.000
K70 Alcoholic liver disease	0.005	0.995	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.004	0.996	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.004	0.996	0.000
D51.2 Transcobalamin II deficiency	0.004	0.996	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.004	0.996	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.004	0.996	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.004	0.996	0.000
Y52.7 Peripheral vasodilators	0.004	0.996	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.004	0.996	0.000
K70.9 Alcoholic liver disease, unspecified	0.004	0.996	0.000
K70.1 Alcoholic hepatitis	0.004	0.996	0.000
S42.1 Fracture of scapula	0.000	0.996	0.004
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.004	0.996	0.000
S42 Fracture of shoulder and upper arm	0.000	0.996	0.004
Y57.5 X-ray contrast media	0.004	0.996	0.000
T88.4 Failed or difficult intubation	0.000	0.996	0.004
D68.2 Hereditary deficiency of other clotting factors	0.004	0.996	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.004	0.996	0.000
Y59 Other and unspecified vaccines and biological substances	0.004	0.996	0.000
D68.0 Von Willebrand's disease	0.004	0.996	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.004	0.996	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.004	0.996	0.000
K70.3 Alcoholic cirrhosis of liver	0.004	0.996	0.000
Y44.5 Thrombolytic drugs	0.004	0.996	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.004	0.996	0.000
S42.2 Fracture of upper end of humerus	0.000	0.996	0.004
Y44.2 Anticoagulants	0.004	0.996	0.000
Y58 Bacterial vaccines	0.004	0.996	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.004	0.996	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.004	0.996	0.000
M25.57 Pain in joint (Ankle and foot)	0.000	0.996	0.004
Y40 Systemic antibiotics	0.004	0.996	0.000
Y48 Anaesthetics and therapeutic gases	0.004	0.996	0.000
D68.5 Primary Thrombophilia	0.003	0.996	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.004	0.996	0.000
Y53.7 Emetics	0.004	0.996	0.000
Y53.6 Antidiarrhoeal drugs	0.004	0.996	0.000
Y53.5 Digestants	0.004	0.996	0.000
Y53.3 Saline and osmotic laxatives	0.004	0.996	0.000
Y53.2 Stimulant laxatives	0.004	0.996	0.000
Y53.0 Histamine H2-receptor antagonists	0.004	0.996	0.000
D86.8 Sarcoidosis of other and combined sites	0.004	0.996	0.000
Y57.7 Vitamins, not elsewhere classified	0.004	0.996	0.000
Y57.6 Other diagnostic agents	0.004	0.996	0.000
Y57.4 Pharmaceutical excipients	0.004	0.996	0.000
Y57.3 Alcohol deterrents	0.004	0.996	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.004	0.996	0.000
Y57.1 Lipotropic drugs	0.004	0.996	0.000
Y57.0 Appetite depressants [anorectics]	0.004	0.996	0.000
D64.4 Congenital dyserythropoietic anaemia	0.004	0.996	0.000
D64.3 Other sideroblastic anaemias	0.004	0.996	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.004	0.996	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.004	0.996	0.000
D64.0 Hereditary sideroblastic anaemia	0.004	0.996	0.000
Y59.3 Immunoglobulin	0.004	0.996	0.000
S42.20 Fracture of upper end of humerus (closed)	0.000	0.996	0.004
Y44.9 Other and unspecified agents affecting blood constituents	0.004	0.996	0.000
Y44.7 Plasma substitutes	0.004	0.996	0.000
Y44.6 Natural blood and blood products	0.004	0.996	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.004	0.996	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.004	0.996	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.004	0.996	0.000
Y56.9 Topical agent, unspecified	0.003	0.996	0.000
Y56.8 Other topical agents	0.003	0.996	0.000
Y56.7 Dental drugs, topically applied	0.003	0.996	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.003	0.996	0.000
Y56.5 Ophthalmological drugs and preparations	0.003	0.996	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.003	0.996	0.000
Y56.3 Emollients, demulcents and protectants	0.003	0.996	0.000
Y56.2 Local astringents and local detergents	0.003	0.996	0.000
Y56.1 Antipruritics	0.003	0.996	0.000
K22.8 Other specified diseases of oesophagus	0.000	0.996	0.004
Y41 Other systemic anti-infectives and antiparasitics	0.003	0.996	0.000
D68.9 Coagulation defect, unspecified	0.003	0.996	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.003	0.996	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.004	0.996	0.000
W13.9 Unspecified place	0.004	0.996	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.004	0.996	0.000
L29 Pruritus	0.004	0.996	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.996	0.000
Y40.9 Systemic antibiotic, unspecified	0.003	0.996	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.996	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.003	0.996	0.000
D64.8 Other specified anaemias	0.003	0.997	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.003	0.997	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.003	0.997	0.000
S42.11 Fracture of scapula (open)	0.000	0.997	0.003
Y46.6 Other and unspecified antiepileptics	0.003	0.997	0.000
L29.2 Pruritus vulvae	0.003	0.997	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.000	0.997	0.003
Y53.1 Other antacids and anti-gastric-secretion drugs	0.003	0.997	0.000
Y59.9 Vaccine or biological substance, unspecified	0.003	0.997	0.000
Y59.8 Other specified vaccines and biological substances	0.003	0.997	0.000
Y59.2 Protozoal vaccines	0.003	0.997	0.000
Y59.1 Rickettsial vaccines	0.003	0.997	0.000
Y59.0 Viral vaccines	0.003	0.997	0.000
H43.8 Other disorders of vitreous body	0.000	0.997	0.003
Y52.1 Calcium-channel blockers	0.003	0.997	0.000
K12.1 Other forms of stomatitis	0.003	0.997	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.003	0.997	0.000
Y46.8 Antispasticity drugs	0.003	0.997	0.000
Y46.7 Anti-Parkinsonism drugs	0.003	0.997	0.000
Y46.5 Valproic acid	0.003	0.997	0.000
Y46.4 Iminostilbenes	0.003	0.997	0.000
Y46.3 Deoxybarbiturates	0.003	0.997	0.000
Y46.2 Hydantoin derivatives	0.003	0.997	0.000
Y46.1 Oxazolidinediones	0.003	0.997	0.000
Y46.0 Succinimides	0.003	0.997	0.000
K70.0 Alcoholic fatty liver	0.003	0.997	0.000
Y41.5 Antiviral drugs	0.003	0.997	0.000
Y47.1 Benzodiazepines	0.003	0.997	0.000
Y48.4 Anaesthetic, unspecified	0.003	0.997	0.000
Y57.8 Other drugs and medicaments	0.003	0.997	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.000	0.997	0.003
Y40.3 Macrolides	0.003	0.997	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.003	0.997	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.003	0.997	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.003	0.997	0.000
Y47.4 Bromine compounds	0.003	0.997	0.000
Y47.3 Paraldehyde	0.003	0.997	0.000
Y47.2 Chloral derivatives	0.003	0.997	0.000
Y47.0 Barbiturates, not elsewhere classified	0.003	0.997	0.000
S42.21 Fracture of upper end of humerus (open)	0.000	0.997	0.003
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.003	0.997	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.000	0.997	0.003
Y50.9 Central nervous system stimulant, unspecified	0.003	0.997	0.000
Y50.8 Other central nervous system stimulants	0.003	0.997	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.003	0.997	0.000
Y50.1 Opioid receptor antagonists	0.003	0.997	0.000
Y50.0 Analeptics	0.003	0.997	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.003	0.997	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.003	0.997	0.000
Y55.5 Anticommon cold drugs	0.003	0.997	0.000
Y55.4 Expectorants	0.003	0.997	0.000
Y55.3 Antitussives	0.003	0.997	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.003	0.997	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.003	0.997	0.000
Y55.0 Oxytocic drugs	0.003	0.997	0.000
Y58.9 Other and unspecified bacterial vaccines	0.003	0.997	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.003	0.997	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.003	0.997	0.000
Y58.5 Diphtheria vaccine	0.003	0.997	0.000
Y58.4 Tetanus vaccine	0.003	0.997	0.000
Y58.3 Plague vaccine	0.003	0.997	0.000
Y58.2 Cholera vaccine	0.003	0.997	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.003	0.997	0.000
Y58.0 BCG vaccine	0.003	0.997	0.000
Y40.7 Antifungal antibiotics, systemically used	0.003	0.997	0.000
Y40.6 Rifamycins	0.003	0.997	0.000
Y40.5 Aminoglycosides	0.003	0.997	0.000
Y40.4 Tetracyclines	0.003	0.997	0.000
Y40.2 Chloramphenicol group	0.003	0.997	0.000
Y48.5 Therapeutic gases	0.003	0.997	0.000
Y48.1 Parenteral anaesthetics	0.003	0.997	0.000
Y48.0 Inhaled anaesthetics	0.003	0.997	0.000
Y42.5 Other oestrogens and progestogens	0.003	0.997	0.000
S42.3 Fracture of shaft of humerus	0.000	0.997	0.003
Y48.3 Local anaesthetics	0.003	0.997	0.000
Y48.2 Other and unspecified general anaesthetics	0.003	0.997	0.000
L29.8 Other pruritus	0.003	0.997	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.003	0.997	0.000
Y41.4 Anthelminthics	0.003	0.997	0.000
Y41.3 Other antiprotozoal drugs	0.003	0.997	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.003	0.997	0.000
Y41.1 Antimycobacterial drugs	0.003	0.997	0.000
Y41.0 Sulphonamides	0.003	0.997	0.000
Y49.9 Psychotropic drug, unspecified	0.003	0.997	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
Y49.7 Psychostimulants with abuse potential	0.003	0.997	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.003	0.997	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.003	0.997	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.003	0.997	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.003	0.997	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.003	0.997	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.997	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.003	0.997	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.997	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.003	0.997	0.000
Y51.0 Anticholinesterase agents	0.003	0.997	0.000
L29.3 Anogenital pruritus, unspecified	0.003	0.997	0.000
L29.1 Pruritus scroti	0.003	0.997	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
H44.2 Degenerative myopia	0.000	0.997	0.003
Y40.8 Other systemic antibiotics	0.003	0.997	0.000
Y49.5 Other antipsychotics and neuroleptics	0.003	0.997	0.000
Y45.2 Propionic acid derivatives	0.003	0.997	0.000
I12.0 Hypertensive renal disease with renal failure	0.003	0.997	0.000
Y42.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
Y42.4 Oral contraceptives	0.003	0.997	0.000
Y42.2 Antithyroid drugs	0.003	0.997	0.000
Y42.1 Thyroid hormones and substitutes	0.003	0.997	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.003	0.997	0.000
S42.4 Fracture of lower end of humerus	0.000	0.997	0.003
D86.9 Sarcoidosis, unspecified	0.003	0.997	0.000
Y54.9 Mineral salts, not elsewhere classified	0.003	0.997	0.000
Y54.8 Agents affecting uric acid metabolism	0.003	0.997	0.000
Y54.7 Agents affecting calcification	0.003	0.997	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.003	0.997	0.000
Y54.4 Loop [high-ceiling] diuretics	0.003	0.997	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.003	0.997	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.003	0.997	0.000
Y54.0 Mineralocorticoids	0.003	0.997	0.000
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.000	0.997	0.002
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.000	0.997	0.002
H44.0 Purulent endophthalmitis	0.000	0.997	0.003
Y45.1 Salicylates	0.003	0.997	0.000
H44 Disorders of globe	0.000	0.997	0.003
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.002	0.997	0.000
Y45.4 Antirheumatics	0.002	0.997	0.000
Y49.2 Other and unspecified antidepressants	0.002	0.997	0.000
Y45.5 4-Aminophenol derivatives	0.002	0.997	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.000	0.997	0.003
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.000	0.997	0.002
W13 Fall from, out of or through building or structure	0.002	0.997	0.000
S40-S49 Injuries to the shoulder and upper arm	0.000	0.997	0.003
Y54.5 Other diuretics	0.002	0.997	0.000
Z99.2 Dependence on renal dialysis	0.003	0.997	0.000
S40 Superficial injury of shoulder and upper arm	0.000	0.997	0.002
Y54.3 Benzothiadiazine derivatives	0.002	0.997	0.000
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.000	0.997	0.002
Y85.0 Sequelae of motor-vehicle accident	0.000	0.997	0.002
D70-D77 Other diseases of blood and blood-forming organs	0.002	0.998	0.000
Y79.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
S42.31 Fracture of shaft of humerus (open)	0.000	0.998	0.002
S41 Open wound of shoulder and upper arm	0.000	0.998	0.002
C85.1 B-cell lymphoma, unspecified	0.002	0.998	0.000
D11.0 Parotid gland	0.002	0.998	0.000
L29.0 Pruritus ani	0.002	0.998	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.002	0.998	0.000
Y45.8 Other analgesics and antipyretics	0.002	0.998	0.000
S41.1 Open wound of upper arm	0.000	0.998	0.002
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.000	0.998	0.002
T21 Burn and corrosion of trunk	0.002	0.998	0.000
O20.0 Threatened abortion	0.002	0.998	0.000
H43 Disorders of vitreous body	0.000	0.998	0.002
Y79 Orthopaedic devices associated with adverse incidents	0.002	0.998	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.002	0.998	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.000	0.998	0.002
G03.9 Meningitis, unspecified	0.002	0.998	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.000	0.998	0.002
H44.9 Disorder of globe, unspecified	0.000	0.998	0.002
H44.8 Other disorders of globe	0.000	0.998	0.002
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.000	0.998	0.002
H44.6 Retained (old) intraocular foreign body, magnetic	0.000	0.998	0.002
H44.5 Degenerated conditions of globe	0.000	0.998	0.002
H44.4 Hypotony of eye	0.000	0.998	0.002
H44.3 Other degenerative disorders of globe	0.000	0.998	0.002
H44.1 Other endophthalmitis	0.000	0.998	0.002
T21.2 Burn of second degree of trunk	0.002	0.998	0.000
T23.1 Burn of first degree of wrist and hand	0.002	0.998	0.000
T23 Burn and corrosion of wrist and hand	0.002	0.998	0.000
X59 Exposure to unspecified factor	0.002	0.998	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.002	0.998	0.000
S40.0 Contusion of shoulder and upper arm	0.000	0.998	0.002
T25.2 Burn of second degree of ankle and foot	0.002	0.998	0.000
T25 Burn and corrosion of ankle and foot	0.002	0.998	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.002	0.998	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.000	0.998	0.002
S86.8 Injury of other muscles and tendons at lower leg level	0.002	0.998	0.000
W13.8 Other specified place	0.002	0.998	0.000
W13.0 Home	0.002	0.998	0.000
W13.7 Farm	0.002	0.998	0.000
W13.6 Industrial and construction area	0.002	0.998	0.000
W13.5 Trade and service area	0.002	0.998	0.000
W13.4 Street and highway	0.002	0.998	0.000
W13.3 Sports and athletics area	0.002	0.998	0.000
W13.2 School, other institution and public administrative area	0.002	0.998	0.000
W13.1 Residential institution	0.002	0.998	0.000
G03 Meningitis due to other and unspecified causes	0.002	0.998	0.000
S48 Traumatic amputation of shoulder and upper arm	0.000	0.998	0.002
S45 Injury of blood vessels at shoulder and upper arm level	0.000	0.998	0.002
S44 Injury of nerves at shoulder and upper arm level	0.000	0.998	0.002
S47 Crushing injury of shoulder and upper arm	0.000	0.998	0.002
X59.4 Street and highway	0.002	0.998	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
S40.8 Other superficial injuries of shoulder and upper arm	0.000	0.998	0.002
G09 Sequelae of inflammatory diseases of central nervous system	0.002	0.998	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.001
D74 Methaemoglobinaemia	0.002	0.998	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.002	0.998	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.002	0.998	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.002	0.998	0.000
S42.41 Fracture of lower end of humerus (open)	0.000	0.998	0.002
O86.4 Pyrexia of unknown origin following delivery	0.002	0.998	0.000
T21.3 Burn of third degree of trunk	0.002	0.998	0.000
X59.3 Sports and athletics area	0.002	0.998	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.002	0.998	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.002	0.998	0.000
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.000	0.998	0.002
S41.7 Multiple open wounds of shoulder and upper arm	0.000	0.998	0.002
S41.0 Open wound of shoulder	0.000	0.998	0.002
T21.0 Burn of unspecified degree of trunk	0.002	0.998	0.000
T20 Burn and corrosion of head and neck	0.002	0.998	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.002	0.998	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.000	0.998	0.002
G01 Meningitis in bacterial diseases classified elsewhere	0.002	0.998	0.000
T20.1 Burn of first degree of head and neck	0.002	0.998	0.000
S13.4 Sprain and strain of cervical spine	0.002	0.998	0.000
T23.2 Burn of second degree of wrist and hand	0.002	0.998	0.000
D73 Diseases of spleen	0.002	0.998	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.002	0.998	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
Chapter XX External causes of morbidity and mortality	0.002	0.998	0.000
S42.40 Fracture of lower end of humerus (closed)	0.000	0.998	0.002
X00.0 Home	0.002	0.998	0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.002	0.998	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
Y71 Cardiovascular devices associated with adverse incidents	0.002	0.998	0.000
T21.7 Corrosion of third degree of trunk	0.002	0.998	0.000
T21.6 Corrosion of second degree of trunk	0.002	0.998	0.000
T21.5 Corrosion of first degree of trunk	0.002	0.998	0.000
T21.4 Corrosion of unspecified degree of trunk	0.002	0.998	0.000
T21.1 Burn of first degree of trunk	0.002	0.998	0.000
H43-H45 Disorders of vitreous body and globe	0.000	0.998	0.002
S42.30 Fracture of shaft of humerus (closed)	0.000	0.998	0.002
H43.2 Crystalline deposits in vitreous body	0.000	0.998	0.002
H43.0 Vitreous prolapse	0.000	0.998	0.002
H81.0 Meniere's disease	0.000	0.998	0.002
Y79.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations