TreeWAS – Variant ID: rs3778872

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H40.1 Primary open-angle glaucoma	0.063	0.937	0.000
H40 Glaucoma	0.036	0.964	0.000
H40.9 Glaucoma, unspecified	0.035	0.965	0.000
R00.2 Palpitations	0.000	0.967	0.033
E04.2 Non-toxic multinodular goitre	0.000	0.968	0.032
H40.5 Glaucoma secondary to other eye disorders	0.028	0.972	0.000
H40.3 Glaucoma secondary to eye trauma	0.026	0.974	0.000
H40.6 Glaucoma secondary to drugs	0.026	0.974	0.000
H40.4 Glaucoma secondary to eye inflammation	0.025	0.974	0.000
H40.8 Other glaucoma	0.025	0.975	0.000
H40.0 Glaucoma suspect	0.021	0.979	0.000
R00 Abnormalities of heart beat	0.000	0.982	0.018
R00.0 Tachycardia, unspecified	0.000	0.983	0.017
E04 Other non-toxic goitre	0.000	0.984	0.016
R00.8 Other and unspecified abnormalities of heart beat	0.000	0.985	0.015
H40-H42 Glaucoma	0.015	0.985	0.000
K61.0 Anal abscess	0.015	0.985	0.000
E04.1 Non-toxic single thyroid nodule	0.000	0.985	0.015
E04.8 Other specified non-toxic goitre	0.000	0.988	0.012
H42 Glaucoma in diseases classified elsewhere	0.011	0.989	0.000
I84.3 External thrombosed haemorrhoids	0.011	0.989	0.000
E04.0 Non-toxic diffuse goitre	0.000	0.989	0.010
K61 Abscess of anal and rectal regions	0.009	0.991	0.000
K50.9 Crohn's disease, unspecified	0.009	0.991	0.000
K61.1 Rectal abscess	0.009	0.991	0.000
K50 Crohn's disease [regional enteritis]	0.009	0.991	0.000
K50.1 Crohn's disease of large intestine	0.009	0.991	0.000
N94.1 Dyspareunia	0.000	0.991	0.009
H42.8 Glaucoma in other diseases classified elsewhere	0.008	0.992	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.008	0.992	0.000
K50.0 Crohn's disease of small intestine	0.008	0.992	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.992	0.008
K61.4 Intrasphincteric abscess	0.007	0.993	0.000
K61.2 Anorectal abscess	0.007	0.993	0.000
K50.8 Other Crohn's disease	0.007	0.993	0.000
M24.2 Disorder of ligament	0.007	0.993	0.000
M24.26 Disorder of ligament (Lower leg)	0.007	0.993	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.007	0.993	0.000
M24.23 Disorder of ligament (Forearm)	0.007	0.993	0.000
K61.3 Ischiorectal abscess	0.006	0.994	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.006	0.994	0.000
M24 Other specific joint derangements	0.006	0.994	0.000
C25.9 Pancreas, unspecified	0.000	0.994	0.006
M24.6 Ankylosis of joint	0.005	0.995	0.000
M24.5 Contracture of joint	0.005	0.995	0.000
M24.24 Disorder of ligament (Hand)	0.005	0.995	0.000
H40.2 Primary angle-closure glaucoma	0.005	0.995	0.000
M24.29 Disorder of ligament (Site unspecified)	0.005	0.995	0.000
M24.28 Disorder of ligament (Other)	0.005	0.995	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.005	0.995	0.000
M24.22 Disorder of ligament (Upper arm)	0.005	0.995	0.000
M24.21 Disorder of ligament (Shoulder region)	0.005	0.995	0.000
M24.20 Disorder of ligament (Multiple sites)	0.005	0.995	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.005	0.995	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.005	0.995	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.005	0.995	0.000
G44.2 Tension-type headache	0.000	0.995	0.005
M24.66 Ankylosis of joint (Lower leg)	0.005	0.995	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.004	0.995	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.004	0.995	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.004	0.995	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.004	0.995	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.005	0.995	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.004	0.995	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.004	0.995	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.004	0.995	0.000
M24.51 Contracture of joint (Shoulder region)	0.004	0.995	0.000
M24.54 Contracture of joint (Hand)	0.004	0.996	0.000
M24.0 Loose body in joint	0.004	0.996	0.000
M24.56 Contracture of joint (Lower leg)	0.004	0.996	0.000
M24.9 Joint derangement, unspecified	0.004	0.996	0.000
M24.7 Protrusio acetabuli	0.004	0.996	0.000
M24.57 Contracture of joint (Ankle and foot)	0.004	0.996	0.000
N81.5 Vaginal enterocele	0.004	0.996	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.004	0.996	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.004	0.996	0.000
M24.68 Ankylosis of joint (Other)	0.004	0.996	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.004	0.996	0.000
M24.64 Ankylosis of joint (Hand)	0.004	0.996	0.000
M24.63 Ankylosis of joint (Forearm)	0.004	0.996	0.000
M24.62 Ankylosis of joint (Upper arm)	0.004	0.996	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.004	0.996	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.004	0.996	0.000
M24.59 Contracture of joint (Site unspecified)	0.004	0.996	0.000
M24.58 Contracture of joint (Other)	0.004	0.996	0.000
M24.53 Contracture of joint (Forearm)	0.004	0.996	0.000
M24.52 Contracture of joint (Upper arm)	0.004	0.996	0.000
M24.50 Contracture of joint (Multiple sites)	0.004	0.996	0.000
N18.9 Chronic renal failure, unspecified	0.000	0.996	0.004
M24.06 Loose body in joint-Lower leg	0.004	0.996	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.004	0.996	0.000
N28.8 Other specified disorders of kidney and ureter	0.000	0.996	0.004
R44.1 Visual hallucinations	0.004	0.996	0.000
M24.1 Other articular cartilage disorders	0.004	0.996	0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.004	0.996	0.000
M24.09 Loose body in joint (Site unspecified)	0.003	0.997	0.000
M24.08 Loose body in joint (Other)	0.003	0.997	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.003	0.997	0.000
M24.04 Loose body in joint (Hand)	0.003	0.997	0.000
M24.03 Loose body in joint (Forearm)	0.003	0.997	0.000
M24.00 Loose body in joint (Multiple sites)	0.003	0.997	0.000
M24.07 Loose body in joint (Ankle and foot)	0.003	0.997	0.000
M24.79 Protrusio acetabuli-Site unspec	0.003	0.997	0.000
M24.78 Protrusio acetabuli-Other	0.003	0.997	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.003	0.997	0.000
M24.76 Protrusio acetabuli-Lower leg	0.003	0.997	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.003	0.997	0.000
M24.74 Protrusio acetabuli-Hand	0.003	0.997	0.000
M24.73 Protrusio acetabuli-Forearm	0.003	0.997	0.000
M24.72 Protrusio acetabuli-Upper arm	0.003	0.997	0.000
M24.71 Protrusio acetabuli-Shldr region	0.003	0.997	0.000
M24.70 Protrusio acetabuli-Mult sites	0.003	0.997	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.003	0.997	0.000
M24.98 Joint derangement, unspecified (Other)	0.003	0.997	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.003	0.997	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.003	0.997	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M24.94 Joint derangement, unspecified (Hand)	0.003	0.997	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.003	0.997	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.003	0.997	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.003	0.997	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.003	0.997	0.000
K92.9 Disease of digestive system, unspecified	0.003	0.997	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
R00.1 Bradycardia, unspecified	0.000	0.997	0.003
M24.02 Loose body in joint (Upper arm)	0.003	0.997	0.000
M24.01 Loose body in joint (Shoulder region)	0.003	0.997	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.003	0.997	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.003	0.997	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.003	0.997	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.003	0.997	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.003	0.997	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.003	0.997	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.003	0.997	0.000
M21.26 Flexion deformity (Lower leg)	0.003	0.997	0.000
M21.1 Varus deformity, not elsewhere classified	0.003	0.997	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.003	0.997	0.000
M24.18 Other articular cartilage disorders (Other)	0.003	0.997	0.000
M24.14 Other articular cartilage disorders (Hand)	0.003	0.997	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.003	0.997	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.003	0.997	0.000
M21.2 Flexion deformity	0.003	0.997	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.003	0.997	0.000
H26.9 Cataract, unspecified	0.003	0.997	0.000
N92.3 Ovulation bleeding	0.000	0.997	0.003
M21.27 Flexion deformity (Ankle and foot)	0.003	0.997	0.000
K92.2 Gastro-intestinal haemorrhage, unspecified	0.003	0.997	0.000
I10 Essential (primary) hypertension	0.000	0.997	0.003
E00-E07 Disorders of thyroid gland	0.000	0.997	0.003
R55 Syncope and collapse	0.000	0.997	0.003
I45.6 Preexcitation syndrome	0.000	0.997	0.003
M24.16 Other articular cartilage disorders (Lower leg)	0.003	0.997	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.002	0.997	0.000
N70.1 Chronic salpingitis and oophoritis	0.000	0.997	0.003
M21 Other acquired deformities of limbs	0.003	0.997	0.000
I86.4 Gastric varices	0.002	0.998	0.000
K92 Other diseases of digestive system	0.002	0.998	0.000
L82 Seborrhoeic keratosis	0.000	0.998	0.002
K91.4 Colostomy and enterostomy malfunction	0.002	0.998	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.002	0.998	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.002	0.998	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.002	0.998	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.002	0.998	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.002	0.998	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.002	0.998	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.002	0.998	0.000
M21.6 Other acquired deformities of ankle and foot	0.002	0.998	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.002	0.998	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.002	0.998	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.002	0.998	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.002	0.998	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
M21.8 Other specified acquired deformities of limbs	0.002	0.998	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.002
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.002	0.998	0.000
I49.5 Sick sinus syndrome	0.000	0.998	0.002
H26.2 Complicated cataract	0.002	0.998	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.002	0.998	0.000
M21.29 Flexion deformity (Site unspecified)	0.002	0.998	0.000
M21.28 Flexion deformity (Other)	0.002	0.998	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.002	0.998	0.000
M21.23 Flexion deformity (Forearm)	0.002	0.998	0.000
M21.22 Flexion deformity (Upper arm)	0.002	0.998	0.000
M21.21 Flexion deformity (Shoulder region)	0.002	0.998	0.000
M21.20 Flexion deformity (Multiple sites)	0.002	0.998	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.002	0.998	0.000
K92.8 Other specified diseases of digestive system	0.002	0.998	0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs	0.002	0.998	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.002	0.998	0.000
D06.9 Cervix, unspecified	0.002	0.998	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.998	0.002
E00 Congenital iodine-deficiency syndrome	0.000	0.998	0.002
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.002	0.998	0.000
C65 Malignant neoplasm of renal pelvis	0.002	0.998	0.000
M21.0 Valgus deformity, not elsewhere classified	0.002	0.998	0.000
C25 Malignant neoplasm of pancreas	0.000	0.998	0.002
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.002	0.998	0.000
C25.1 Body of pancreas	0.000	0.998	0.002
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.998	0.002
N36.2 Urethral caruncle	0.000	0.998	0.002
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.998	0.002
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.002	0.998	0.000
M21.4 Flat foot [pes planus] (acquired)	0.002	0.998	0.000
F02.3 Dementia in Parkinson's disease	0.002	0.998	0.000
M21.9 Acquired deformity of limb, unspecified	0.002	0.998	0.000
M21.24 Flexion deformity (Hand)	0.002	0.998	0.000
M21.7 Unequal limb length (acquired)	0.002	0.998	0.000
R63.8 Other symptoms and signs concerning food and fluid intake	0.002	0.998	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.002	0.998	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.002	0.998	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.998	0.002
E07 Other disorders of thyroid	0.000	0.998	0.002
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.998	0.002
I45 Other conduction disorders	0.000	0.998	0.002
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.002	0.998	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.002	0.998	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.002	0.998	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.002	0.998	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.002	0.998	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.002	0.998	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.002	0.998	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.002	0.998	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.002	0.998	0.000
L93.0 Discoid lupus erythematosus	0.002	0.998	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.000	0.998	0.002
I45.9 Conduction disorder, unspecified	0.000	0.998	0.002
E03 Other hypothyroidism	0.000	0.998	0.002
H61.0 Perichondritis of external ear	0.000	0.998	0.002
E06 Thyroiditis	0.000	0.998	0.002
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.002	0.998	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.002	0.998	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.002	0.998	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.002	0.998	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.002	0.998	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.002	0.998	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.002	0.998	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.002	0.998	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.002	0.998	0.000
E07.8 Other specified disorders of thyroid	0.000	0.998	0.002
K91.0 Vomiting following gastro-intestinal surgery	0.002	0.998	0.000
I11 Hypertensive heart disease	0.000	0.998	0.002
M79.10 Myalgia (Multiple sites)	0.002	0.998	0.000
C68.0 Urethra	0.002	0.998	0.000
E03.8 Other specified hypothyroidism	0.000	0.998	0.002
K70.3 Alcoholic cirrhosis of liver	0.002	0.998	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.998	0.002
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.998	0.002
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.998	0.002
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.998	0.002
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.998	0.002
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.998	0.002
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.998	0.002
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.998	0.002
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.998	0.002
K91.9 Postprocedural disorder of digestive system, unspecified	0.002	0.998	0.000
K91.1 Postgastric surgery syndromes	0.002	0.998	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.002	0.998	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.002	0.998	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.002	0.998	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.001	0.998	0.001
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
C25.8 Overlapping lesion of pancreas	0.000	0.998	0.002
C25.7 Other parts of pancreas	0.000	0.998	0.002
C25.4 Endocrine pancreas	0.000	0.998	0.002
D68.9 Coagulation defect, unspecified	0.000	0.998	0.002
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.002	0.998	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.002	0.998	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.002	0.998	0.000
I45.4 Nonspecific intraventricular block	0.000	0.998	0.002
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.002	0.998	0.000
M21.48 Flat foot [pes planus] (acquired)-Other	0.002	0.998	0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.002	0.998	0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.002	0.998	0.000
M21.44 Flat foot [pes planus] (acquired)-Hand	0.002	0.998	0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.002	0.998	0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.002	0.998	0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.002	0.998	0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.002	0.998	0.000
I45.3 Trifascicular block	0.000	0.998	0.002
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.002	0.998	0.000
M21.98 Acquired deformity of limb, unspecified-Other	0.002	0.998	0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.002	0.998	0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.002	0.998	0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M21.94 Acquired deformity of limb, unspecified (Hand)	0.002	0.998	0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.002	0.998	0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.002	0.998	0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.002	0.998	0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.002	0.998	0.000
I45.5 Other specified heart block	0.000	0.998	0.002
K63.0 Abscess of intestine	0.002	0.998	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.002	0.998	0.000
M21.3 Wrist or foot drop (acquired)	0.002	0.998	0.000
C25.3 Pancreatic duct	0.000	0.998	0.002
I45.2 Bifascicular block	0.000	0.998	0.002
K91.5 Postcholecystectomy syndrome	0.002	0.998	0.000
M21.79 Unequal limb length (acquired) (Site unspecified)	0.001	0.998	0.000
M21.78 Unequal limb length (acquired)-Other	0.001	0.998	0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.001	0.998	0.000
M21.76 Unequal limb length (acquired) (Lower leg)	0.001	0.998	0.000
M21.74 Unequal limb length (acquired) (Hand)	0.001	0.998	0.000
M21.73 Unequal limb length (acquired) (Forearm)	0.001	0.998	0.000
M21.72 Unequal limb length (acquired) (Upper arm)	0.001	0.998	0.000
M21.71 Unequal limb length (acquired)-Shldr region	0.001	0.998	0.000
M21.70 Unequal limb length (acquired) (Multiple sites)	0.001	0.998	0.000
E07.1 Dyshormogenetic goitre	0.000	0.998	0.002
E07.0 Hypersecretion of calcitonin	0.000	0.998	0.002
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.002	0.998	0.000
M22.4 Chondromalacia patellae	0.002	0.998	0.000
I45.0 Right fascicular block	0.000	0.998	0.002
T81.3 Disruption of operation wound, not elsewhere classified	0.002	0.998	0.000
D52.9 Folate deficiency anaemia, unspecified	0.000	0.998	0.002
F02.8 Dementia in other specified diseases classified elsewhere	0.002	0.998	0.000
I45.1 Other and unspecified right bundle-branch block	0.000	0.998	0.002
E03.5 Myxoedema coma	0.000	0.998	0.002
E03.4 Atrophy of thyroid (acquired)	0.000	0.998	0.002
E03.3 Postinfectious hypothyroidism	0.000	0.998	0.002
E03.1 Congenital hypothyroidism without goitre	0.000	0.998	0.002
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.998	0.002
C64-C68 Malignant neoplasms of urinary tract	0.002	0.998	0.000
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.001	0.998	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
E06.5 Other chronic thyroiditis	0.000	0.998	0.001
E06.4 Drug-induced thyroiditis	0.000	0.998	0.001
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.998	0.001
E06.1 Subacute thyroiditis	0.000	0.998	0.001
E06.0 Acute thyroiditis	0.000	0.998	0.001
K90-K93 Other diseases of the digestive system	0.002	0.998	0.000
I77.1 Stricture of artery	0.000	0.998	0.002
E06.9 Thyroiditis, unspecified	0.000	0.998	0.002
N62 Hypertrophy of breast	0.002	0.998	0.000
K50-K52 Noninfective enteritis and colitis	0.002	0.998	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.998	0.002
I10-I15 Hypertensive diseases	0.000	0.998	0.002
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.001	0.998	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.001	0.998	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.001	0.998	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.001	0.998	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.001	0.998	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.001	0.998	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.001	0.998	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.001	0.998	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.001	0.998	0.000
I86.1 Scrotal varices	0.002	0.998	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.998	0.002
I45.8 Other specified conduction disorders	0.000	0.998	0.001
K63.2 Fistula of intestine	0.002	0.998	0.000
R06.4 Hyperventilation	0.000	0.998	0.002
Y52 Agents primarily affecting the cardiovascular system	0.000	0.998	0.002
M19.14 Post-traumatic arthrosis of other joints (Hand)	0.002	0.998	0.000
S92.30 Fracture of metatarsal bone (closed)	0.002	0.998	0.000
C25.2 Tail of pancreas	0.000	0.998	0.001
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.002	0.998	0.000
K92.1 Melaena	0.002	0.998	0.000
I86 Varicose veins of other sites	0.002	0.998	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.001	0.998	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.001	0.998	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.001	0.998	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.001	0.998	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.001	0.998	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.001	0.998	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.001	0.998	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.001	0.998	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.001	0.998	0.000
C68.9 Urinary organ, unspecified	0.001	0.998	0.000
C68.8 Overlapping lesion of urinary organs	0.001	0.998	0.000
C68.1 Paraurethral glands	0.001	0.998	0.000
M34.1 CR(E)ST syndrome	0.002	0.998	0.000
G44 Other headache syndromes	0.000	0.998	0.002
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.001	0.998	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.998	0.002
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.998	0.002
C66 Malignant neoplasm of ureter	0.001	0.998	0.000
H26 Other cataract	0.002	0.998	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.998	0.001
M46.46 Discitis, unspecified (Lumbar region)	0.000	0.998	0.001
S92.50 Fracture of other toe (closed)	0.001	0.998	0.000
I85.9 Oesophageal varices without bleeding	0.002	0.998	0.000
K74.6 Other and unspecified cirrhosis of liver	0.002	0.998	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.001	0.998	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.001	0.998	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.001	0.998	0.000
S82.40 Fracture of fibula alone (closed)	0.000	0.998	0.001
C25.0 Head of pancreas	0.000	0.998	0.001
I12.9 Hypertensive renal disease without renal failure	0.000	0.998	0.001
N70.9 Salpingitis and oophoritis, unspecified	0.000	0.998	0.001
T50.9 Other and unspecified drugs, medicaments and biological substances	0.001	0.998	0.000
F02 Dementia in other diseases classified elsewhere	0.001	0.998	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.001	0.999	0.000
N70 Salpingitis and oophoritis	0.000	0.999	0.001
I15.1 Hypertension secondary to other renal disorders	0.001	0.999	0.000
I12 Hypertensive renal disease	0.000	0.999	0.001
I86.8 Varicose veins of other specified sites	0.001	0.999	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.001	0.999	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.000	0.999	0.001
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.999	0.001
N60.0 Solitary cyst of breast	0.001	0.999	0.000
I13 Hypertensive heart and renal disease	0.000	0.999	0.001
I86.3 Vulval varices	0.001	0.999	0.000
I86.2 Pelvic varices	0.001	0.999	0.000
I86.0 Sublingual varices	0.001	0.999	0.000
S90.3 Contusion of other and unspecified parts of foot	0.001	0.999	0.000
S92.3 Fracture of metatarsal bone	0.001	0.999	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.000	0.999	0.001
Y52.7 Peripheral vasodilators	0.000	0.999	0.001
G44.1 Vascular headache, not elsewhere classified	0.000	0.999	0.001
R01.0 Benign and innocent cardiac murmurs	0.000	0.999	0.001
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.001	0.999	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.001	0.999	0.000
E06.3 Autoimmune thyroiditis	0.000	0.999	0.001
G44.4 Drug-induced headache, not elsewhere classified	0.000	0.999	0.001
H26.3 Drug-induced cataract	0.001	0.999	0.000
S92.5 Fracture of other toe	0.001	0.999	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.999	0.001
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.001	0.999	0.000
I15 Secondary hypertension	0.001	0.999	0.001
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.001	0.999	0.000
F02.2 Dementia in Huntington's disease	0.001	0.999	0.000
F02.1 Dementia in Creutzfeldt-Jakob disease	0.001	0.999	0.000
F02.0 Dementia in Pick's disease	0.001	0.999	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.001	0.999	0.000
K93.1 Megacolon in Chagas' disease	0.001	0.999	0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.001	0.999	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.999	0.001
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.001	0.999	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.001	0.999	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.001	0.999	0.000
N18.5 Chronic kidney disease, stage 5	0.000	0.999	0.001
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.999	0.001
G44.8 Other specified headache syndromes	0.000	0.999	0.001
N70.0 Acute salpingitis and oophoritis	0.000	0.999	0.001
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.000	0.999	0.001
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.999	0.001
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.999	0.001
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.999	0.001
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.999	0.001
K52.3 Indeterminate colitis	0.001	0.999	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.001	0.999	0.000
R44.2 Other hallucinations	0.001	0.999	0.000
S99.9 Unspecified injury of ankle and foot	0.001	0.999	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.999	0.001
S92.31 Fracture of metatarsal bone (open)	0.001	0.999	0.000
G44.0 Cluster headache syndrome	0.000	0.999	0.001
H26.1 Traumatic cataract	0.001	0.999	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.001	0.999	0.000
L53.8 Other specified erythematous conditions	0.001	0.999	0.000
S92.51 Fracture of other toe (open)	0.001	0.999	0.000
H26.0 Infantile, juvenile and presenile cataract	0.001	0.999	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.000	0.999	0.001
M48.07 Spinal stenosis (Lumbosacral region)	0.000	0.999	0.001
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.001	0.999	0.000
D09.0 Bladder	0.001	0.999	0.000
G57.6 Lesion of plantar nerve	0.001	0.999	0.000
I15.8 Other secondary hypertension	0.001	0.999	0.001
I15.2 Hypertension secondary to endocrine disorders	0.001	0.999	0.001
I15.0 Renovascular hypertension	0.001	0.999	0.001
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.001	0.999	0.000
N60.4 Mammary duct ectasia	0.001	0.999	0.000
S92 Fracture of foot, except ankle	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations