TreeWAS – Variant ID: rs3782889

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D22.5 Melanocytic naevi of trunk	0.028	0.972	0.000
K58.9 Irritable bowel syndrome without diarrhoea	0.026	0.974	0.000
Y43.3 Other antineoplastic drugs	0.020	0.980	0.000
N17.9 Acute renal failure, unspecified	0.016	0.984	0.000
Y43 Primarily systemic agents	0.016	0.984	0.000
N17 Acute renal failure	0.013	0.987	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.013	0.987	0.000
N18 Chronic renal failure	0.012	0.988	0.000
Y43.1 Antineoplastic antimetabolites	0.012	0.988	0.000
Y43.0 Antiallergic and antiemetic drugs	0.012	0.988	0.000
N17-N19 Renal failure	0.012	0.988	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.012	0.988	0.000
Y43.9 Primarily systemic agent, unspecified	0.011	0.989	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.011	0.989	0.000
Y43.6 Enzymes, not elsewhere classified	0.011	0.989	0.000
Y43.5 Acidifying and alkalising agents	0.011	0.989	0.000
Y43.2 Antineoplastic natural products	0.011	0.989	0.000
N18.2 Chronic kidney disease, stage 2	0.011	0.989	0.000
N18.9 Chronic renal failure, unspecified	0.011	0.989	0.000
Y57 Other and unspecified drugs and medicaments	0.010	0.989	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.010	0.990	0.000
N18.4 Chronic kidney disease, stage 4	0.010	0.990	0.000
Y40 Systemic antibiotics	0.010	0.990	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.010	0.990	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.010	0.990	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.010	0.990	0.000
Y45.0 Opioids and related analgesics	0.010	0.990	0.000
N19 Unspecified renal failure	0.010	0.990	0.000
N17.8 Other acute renal failure	0.010	0.990	0.000
N17.2 Acute renal failure with medullary necrosis	0.010	0.990	0.000
N17.1 Acute renal failure with acute cortical necrosis	0.010	0.990	0.000
Y45.1 Salicylates	0.010	0.990	0.000
N17.0 Acute renal failure with tubular necrosis	0.010	0.990	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.010	0.990	0.000
Y45.8 Other analgesics and antipyretics	0.010	0.990	0.000
Y52 Agents primarily affecting the cardiovascular system	0.010	0.990	0.000
Y59 Other and unspecified vaccines and biological substances	0.009	0.990	0.000
Y58 Bacterial vaccines	0.009	0.990	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.009	0.990	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.009	0.990	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.009	0.990	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.009	0.990	0.000
Y48 Anaesthetics and therapeutic gases	0.009	0.991	0.000
Y43.4 Immunosuppressive agents	0.009	0.991	0.000
Y44 Agents primarily affecting blood constituents	0.009	0.991	0.000
Y40.8 Other systemic antibiotics	0.009	0.991	0.000
Y40.5 Aminoglycosides	0.009	0.991	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.009	0.991	0.000
N18.1 Chronic kidney disease, stage 1	0.009	0.991	0.000
Y45.2 Propionic acid derivatives	0.009	0.991	0.000
N18.5 Chronic kidney disease, stage 5	0.009	0.991	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.009	0.991	0.000
N18.8 Other chronic renal failure	0.009	0.991	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.009	0.991	0.000
Y45.5 4-Aminophenol derivatives	0.009	0.991	0.000
Y45.4 Antirheumatics	0.009	0.991	0.000
N18.3 Chronic kidney disease, stage 3	0.009	0.991	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.009	0.991	0.000
Y57.9 Drug or medicament, unspecified	0.008	0.991	0.000
Y53.4 Other laxatives	0.008	0.992	0.000
N28.1 Cyst of kidney, acquired	0.008	0.992	0.000
Y49.2 Other and unspecified antidepressants	0.008	0.992	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.008	0.992	0.000
Y49.5 Other antipsychotics and neuroleptics	0.008	0.992	0.000
Y46.4 Iminostilbenes	0.008	0.992	0.000
Y57.5 X-ray contrast media	0.008	0.992	0.000
Y57.8 Other drugs and medicaments	0.008	0.992	0.000
Y57.7 Vitamins, not elsewhere classified	0.008	0.992	0.000
Y57.6 Other diagnostic agents	0.008	0.992	0.000
Y57.4 Pharmaceutical excipients	0.008	0.992	0.000
Y57.3 Alcohol deterrents	0.008	0.992	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.008	0.992	0.000
Y57.1 Lipotropic drugs	0.008	0.992	0.000
Y57.0 Appetite depressants [anorectics]	0.008	0.992	0.000
Y49.9 Psychotropic drug, unspecified	0.008	0.992	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.008	0.992	0.000
Y49.7 Psychostimulants with abuse potential	0.008	0.992	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.008	0.992	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.008	0.992	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.008	0.992	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.008	0.992	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.008	0.992	0.000
Y40.7 Antifungal antibiotics, systemically used	0.008	0.992	0.000
Y40.6 Rifamycins	0.008	0.992	0.000
Y40.4 Tetracyclines	0.008	0.992	0.000
Y40.2 Chloramphenicol group	0.008	0.992	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.007	0.992	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.007	0.992	0.000
Y53.7 Emetics	0.007	0.992	0.000
Y53.6 Antidiarrhoeal drugs	0.007	0.992	0.000
Y53.5 Digestants	0.007	0.992	0.000
Y53.3 Saline and osmotic laxatives	0.007	0.992	0.000
Y53.2 Stimulant laxatives	0.007	0.992	0.000
Y53.0 Histamine H2-receptor antagonists	0.007	0.992	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.007	0.992	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.007	0.992	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.007	0.992	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.007	0.992	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.007	0.992	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.007	0.992	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.007	0.992	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.007	0.992	0.000
Y51.0 Anticholinesterase agents	0.007	0.992	0.000
Y46.8 Antispasticity drugs	0.007	0.992	0.000
Y46.7 Anti-Parkinsonism drugs	0.007	0.992	0.000
Y46.6 Other and unspecified antiepileptics	0.007	0.992	0.000
Y46.5 Valproic acid	0.007	0.992	0.000
Y46.3 Deoxybarbiturates	0.007	0.992	0.000
Y46.2 Hydantoin derivatives	0.007	0.992	0.000
Y46.1 Oxazolidinediones	0.007	0.992	0.000
Y46.0 Succinimides	0.007	0.992	0.000
Y40.3 Macrolides	0.007	0.992	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.007	0.993	0.000
N18.0 End-stage renal disease	0.007	0.993	0.000
Y54.3 Benzothiadiazine derivatives	0.007	0.993	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.007	0.993	0.000
Y54.9 Mineral salts, not elsewhere classified	0.007	0.993	0.000
Y54.8 Agents affecting uric acid metabolism	0.007	0.993	0.000
Y54.7 Agents affecting calcification	0.007	0.993	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.007	0.993	0.000
Y54.4 Loop [high-ceiling] diuretics	0.007	0.993	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.007	0.993	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.007	0.993	0.000
Y54.0 Mineralocorticoids	0.007	0.993	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.007	0.993	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.007	0.993	0.000
Y52.7 Peripheral vasodilators	0.007	0.993	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.007	0.993	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.007	0.993	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.007	0.993	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.007	0.993	0.000
Y47.4 Bromine compounds	0.007	0.993	0.000
Y47.3 Paraldehyde	0.007	0.993	0.000
Y47.2 Chloral derivatives	0.007	0.993	0.000
Y47.1 Benzodiazepines	0.007	0.993	0.000
Y47.0 Barbiturates, not elsewhere classified	0.007	0.993	0.000
Y50.9 Central nervous system stimulant, unspecified	0.007	0.993	0.000
Y50.8 Other central nervous system stimulants	0.007	0.993	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.007	0.993	0.000
Y50.1 Opioid receptor antagonists	0.007	0.993	0.000
Y50.0 Analeptics	0.007	0.993	0.000
Y54.5 Other diuretics	0.007	0.993	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.007	0.993	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.007	0.993	0.000
Y55.5 Anticommon cold drugs	0.007	0.993	0.000
Y55.4 Expectorants	0.007	0.993	0.000
Y55.3 Antitussives	0.007	0.993	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.007	0.993	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.007	0.993	0.000
Y55.0 Oxytocic drugs	0.007	0.993	0.000
Y58.9 Other and unspecified bacterial vaccines	0.007	0.993	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.007	0.993	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.007	0.993	0.000
Y58.5 Diphtheria vaccine	0.007	0.993	0.000
Y58.4 Tetanus vaccine	0.007	0.993	0.000
Y58.3 Plague vaccine	0.007	0.993	0.000
Y58.2 Cholera vaccine	0.007	0.993	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.007	0.993	0.000
Y58.0 BCG vaccine	0.007	0.993	0.000
Y59.9 Vaccine or biological substance, unspecified	0.007	0.993	0.000
Y59.8 Other specified vaccines and biological substances	0.007	0.993	0.000
Y59.3 Immunoglobulin	0.007	0.993	0.000
Y59.2 Protozoal vaccines	0.007	0.993	0.000
Y59.1 Rickettsial vaccines	0.007	0.993	0.000
Y59.0 Viral vaccines	0.007	0.993	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.007	0.993	0.000
Y41.5 Antiviral drugs	0.007	0.993	0.000
Y41.4 Anthelminthics	0.007	0.993	0.000
Y41.3 Other antiprotozoal drugs	0.007	0.993	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.007	0.993	0.000
Y41.1 Antimycobacterial drugs	0.007	0.993	0.000
Y41.0 Sulphonamides	0.007	0.993	0.000
Y42.5 Other oestrogens and progestogens	0.007	0.993	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.007	0.993	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.007	0.993	0.000
Y48.5 Therapeutic gases	0.007	0.993	0.000
Y48.4 Anaesthetic, unspecified	0.007	0.993	0.000
Y48.2 Other and unspecified general anaesthetics	0.007	0.993	0.000
Y48.1 Parenteral anaesthetics	0.007	0.993	0.000
Y48.0 Inhaled anaesthetics	0.007	0.993	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.007	0.993	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.007	0.993	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.007	0.993	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.007	0.993	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.007	0.993	0.000
Y44.7 Plasma substitutes	0.007	0.993	0.000
Y44.6 Natural blood and blood products	0.007	0.993	0.000
Y44.5 Thrombolytic drugs	0.007	0.993	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.007	0.993	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.007	0.993	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.007	0.993	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.007	0.993	0.000
Y56.9 Topical agent, unspecified	0.007	0.993	0.000
Y56.8 Other topical agents	0.007	0.993	0.000
Y56.7 Dental drugs, topically applied	0.007	0.993	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.007	0.993	0.000
Y56.5 Ophthalmological drugs and preparations	0.007	0.993	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.007	0.993	0.000
Y56.3 Emollients, demulcents and protectants	0.007	0.993	0.000
Y56.2 Local astringents and local detergents	0.007	0.993	0.000
Y56.1 Antipruritics	0.007	0.993	0.000
Y48.3 Local anaesthetics	0.007	0.993	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.007	0.993	0.000
Y40.9 Systemic antibiotic, unspecified	0.006	0.993	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.006	0.993	0.000
I73.9 Peripheral vascular disease, unspecified	0.000	0.993	0.007
Y42.9 Other and unspecified hormone antagonists	0.006	0.993	0.000
Y42.4 Oral contraceptives	0.006	0.993	0.000
Y42.2 Antithyroid drugs	0.006	0.993	0.000
Y42.1 Thyroid hormones and substitutes	0.006	0.993	0.000
Y52.1 Calcium-channel blockers	0.006	0.994	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.006	0.994	0.000
Y44.2 Anticoagulants	0.006	0.994	0.000
K58 Irritable bowel syndrome	0.006	0.994	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.006	0.994	0.000
Y40.0 Penicillins	0.006	0.994	0.000
Y42.7 Androgens and anabolic congeners	0.006	0.994	0.000
G20 Parkinson's disease	0.006	0.994	0.000
M24.07 Loose body in joint (Ankle and foot)	0.006	0.994	0.000
M24.0 Loose body in joint	0.005	0.995	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.005	0.995	0.000
Z51.5 Palliative care	0.005	0.995	0.000
M24 Other specific joint derangements	0.005	0.995	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.005	0.995	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.005	0.995	0.000
M24.1 Other articular cartilage disorders	0.005	0.995	0.000
M24.01 Loose body in joint (Shoulder region)	0.004	0.996	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.004	0.996	0.000
N28.0 Ischaemia and infarction of kidney	0.004	0.996	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.004	0.996	0.000
I73 Other peripheral vascular diseases	0.000	0.996	0.004
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.996	0.004
M20.4 Other hammer toe(s) (acquired)	0.000	0.996	0.004
H93.1 Tinnitus	0.004	0.996	0.000
M24.2 Disorder of ligament	0.004	0.996	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.004	0.996	0.000
M24.09 Loose body in joint (Site unspecified)	0.004	0.996	0.000
M24.08 Loose body in joint (Other)	0.004	0.996	0.000
M24.06 Loose body in joint-Lower leg	0.004	0.996	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.004	0.996	0.000
M24.04 Loose body in joint (Hand)	0.004	0.996	0.000
M24.03 Loose body in joint (Forearm)	0.004	0.996	0.000
M24.00 Loose body in joint (Multiple sites)	0.004	0.996	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.004	0.996	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.004	0.996	0.000
M24.6 Ankylosis of joint	0.004	0.996	0.000
I73.0 Raynaud's syndrome	0.000	0.996	0.004
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.004	0.996	0.000
M24.02 Loose body in joint (Upper arm)	0.004	0.996	0.000
M24.9 Joint derangement, unspecified	0.004	0.996	0.000
M24.7 Protrusio acetabuli	0.004	0.996	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.004	0.996	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.004	0.996	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.004	0.996	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.004	0.996	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.004	0.996	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.004	0.996	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.004	0.996	0.000
C18.7 Sigmoid colon	0.004	0.996	0.000
M24.26 Disorder of ligament (Lower leg)	0.004	0.996	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.004	0.996	0.000
M24.5 Contracture of joint	0.003	0.996	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.003	0.996	0.000
M24.18 Other articular cartilage disorders (Other)	0.003	0.996	0.000
M24.14 Other articular cartilage disorders (Hand)	0.003	0.996	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.003	0.996	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.003	0.996	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.003	0.996	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.003	0.996	0.000
C90.0 Multiple myeloma	0.003	0.996	0.000
Z29.2 Other prophylactic chemotherapy	0.000	0.997	0.003
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.003	0.997	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.003	0.997	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.003	0.997	0.000
E83.5 Disorders of calcium metabolism	0.003	0.997	0.000
I73.8 Other specified peripheral vascular diseases	0.000	0.997	0.003
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.997	0.003
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.003	0.997	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.003	0.997	0.000
N81.4 Uterovaginal prolapse, unspecified	0.000	0.997	0.003
M24.29 Disorder of ligament (Site unspecified)	0.003	0.997	0.000
M24.28 Disorder of ligament (Other)	0.003	0.997	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.003	0.997	0.000
M24.22 Disorder of ligament (Upper arm)	0.003	0.997	0.000
M24.21 Disorder of ligament (Shoulder region)	0.003	0.997	0.000
M24.20 Disorder of ligament (Multiple sites)	0.003	0.997	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.003	0.997	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.003	0.997	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.003	0.997	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.003	0.997	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.003	0.997	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.003	0.997	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.003	0.997	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.003	0.997	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.003	0.997	0.000
M24.68 Ankylosis of joint (Other)	0.003	0.997	0.000
M24.66 Ankylosis of joint (Lower leg)	0.003	0.997	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.003	0.997	0.000
M24.64 Ankylosis of joint (Hand)	0.003	0.997	0.000
M24.63 Ankylosis of joint (Forearm)	0.003	0.997	0.000
M24.62 Ankylosis of joint (Upper arm)	0.003	0.997	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.003	0.997	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.003	0.997	0.000
E83.4 Disorders of magnesium metabolism	0.003	0.997	0.000
M24.24 Disorder of ligament (Hand)	0.003	0.997	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.003	0.997	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.003	0.997	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.003	0.997	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.003	0.997	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.003	0.997	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
K35.3 Acute appendicitis with localized peritonitis	0.000	0.997	0.003
Z29 Need for other prophylactic measures	0.000	0.997	0.003
J32.9 Chronic sinusitis, unspecified	0.000	0.997	0.003
Z29.0 Isolation	0.000	0.997	0.003
M24.23 Disorder of ligament (Forearm)	0.003	0.997	0.000
M24.79 Protrusio acetabuli-Site unspec	0.003	0.997	0.000
M24.78 Protrusio acetabuli-Other	0.003	0.997	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.003	0.997	0.000
M24.76 Protrusio acetabuli-Lower leg	0.003	0.997	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.003	0.997	0.000
M24.74 Protrusio acetabuli-Hand	0.003	0.997	0.000
M24.73 Protrusio acetabuli-Forearm	0.003	0.997	0.000
M24.72 Protrusio acetabuli-Upper arm	0.003	0.997	0.000
M24.71 Protrusio acetabuli-Shldr region	0.003	0.997	0.000
M24.70 Protrusio acetabuli-Mult sites	0.003	0.997	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.003	0.997	0.000
M24.98 Joint derangement, unspecified (Other)	0.003	0.997	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.003	0.997	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.003	0.997	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M24.94 Joint derangement, unspecified (Hand)	0.003	0.997	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.003	0.997	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.003	0.997	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.003	0.997	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.003	0.997	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.003	0.997	0.000
M24.56 Contracture of joint (Lower leg)	0.003	0.997	0.000
M24.59 Contracture of joint (Site unspecified)	0.003	0.997	0.000
M24.58 Contracture of joint (Other)	0.003	0.997	0.000
M24.57 Contracture of joint (Ankle and foot)	0.003	0.997	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.003	0.997	0.000
M24.53 Contracture of joint (Forearm)	0.003	0.997	0.000
M24.52 Contracture of joint (Upper arm)	0.003	0.997	0.000
M24.51 Contracture of joint (Shoulder region)	0.003	0.997	0.000
M24.50 Contracture of joint (Multiple sites)	0.003	0.997	0.000
K35 Acute appendicitis	0.000	0.997	0.003
N64.5 Other signs and symptoms in breast	0.000	0.997	0.003
C92.1 Chronic myeloid leukaemia	0.003	0.997	0.000
J32.8 Other chronic sinusitis	0.000	0.997	0.003
C91 Lymphoid leukaemia	0.003	0.997	0.000
E83 Disorders of mineral metabolism	0.003	0.997	0.000
M25.77 Osteophyte (Ankle and foot)	0.003	0.997	0.000
H93 Other disorders of ear, not elsewhere classified	0.003	0.997	0.000
C90.2 Plasmacytoma, extramedullary	0.003	0.997	0.000
F02.3 Dementia in Parkinson's disease	0.003	0.997	0.000
Z29.1 Prophylactic immunotherapy	0.000	0.997	0.003
G20-G26 Extrapyramidal and movement disorders	0.003	0.997	0.000
C91.0 Acute lymphoblastic leukaemia	0.003	0.997	0.000
Z29.8 Other specified prophylactic measures	0.000	0.997	0.002
M24.54 Contracture of joint (Hand)	0.002	0.997	0.000
Z29.9 Prophylactic measure, unspecified	0.000	0.997	0.002
C92 Myeloid leukaemia	0.002	0.997	0.000
F02 Dementia in other diseases classified elsewhere	0.002	0.997	0.000
F03 Unspecified dementia	0.002	0.997	0.000
H93.2 Other abnormal auditory perceptions	0.002	0.998	0.000
C22.9 Liver, unspecified	0.002	0.998	0.000
C90.3 Solitary plasmacytoma	0.002	0.998	0.000
C90.1 Plasma cell leukaemia	0.002	0.998	0.000
C91.4 Hairy-cell leukaemia	0.002	0.998	0.000
C91.1 Chronic lymphocytic leukaemia	0.002	0.998	0.000
K58.0 Irritable bowel syndrome with diarrhoea	0.002	0.998	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
J32.0 Chronic maxillary sinusitis	0.000	0.998	0.002
C18.4 Transverse colon	0.002	0.998	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.000	0.998	0.002
F02.0 Dementia in Pick's disease	0.002	0.998	0.000
F05.9 Delirium, unspecified	0.002	0.998	0.000
E83.3 Disorders of phosphorus metabolism	0.002	0.998	0.000
C91.9 Lymphoid leukaemia, unspecified	0.002	0.998	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.002	0.998	0.000
J32 Chronic sinusitis	0.000	0.998	0.002
C91.8 Mature B-cell leukaemia Burkitt-type	0.002	0.998	0.000
C91.7 Other lymphoid leukaemia	0.002	0.998	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.002	0.998	0.000
C91.5 Adult T-cell leukaemia	0.002	0.998	0.000
C91.3 Prolymphocytic leukaemia	0.002	0.998	0.000
C91.2 Subacute lymphocytic leukaemia	0.002	0.998	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.002	0.998	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.002	0.998	0.000
E83.8 Other disorders of mineral metabolism	0.002	0.998	0.000
E83.2 Disorders of zinc metabolism	0.002	0.998	0.000
E83.0 Disorders of copper metabolism	0.002	0.998	0.000
C95 Leukaemia of unspecified cell type	0.002	0.998	0.000
C93 Monocytic leukaemia	0.002	0.998	0.000
G25 Other extrapyramidal and movement disorders	0.002	0.998	0.000
S82.10 Fracture of upper end of tibia (closed)	0.002	0.998	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.002	0.998	0.000
H93.8 Other specified disorders of ear	0.002	0.998	0.000
H93.3 Disorders of acoustic nerve	0.002	0.998	0.000
H93.0 Degenerative and vascular disorders of ear	0.002	0.998	0.000
D68 Other coagulation defects	0.002	0.998	0.000
K35.2 Acute appendicitis with generalized peritonitis	0.000	0.998	0.002
N88.2 Stricture and stenosis of cervix uteri	0.000	0.998	0.002
D68.0 Von Willebrand's disease	0.002	0.998	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.002	0.998	0.000
F00 Dementia in Alzheimer's disease	0.002	0.998	0.000
G23 Other degenerative diseases of basal ganglia	0.002	0.998	0.000
G21 Secondary Parkinsonism	0.002	0.998	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.002	0.998	0.000
G22 Parkinsonism in diseases classified elsewhere	0.002	0.998	0.000
X78.0 Home	0.002	0.998	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.002	0.998	0.000
K35.9 Acute appendicitis, unspecified	0.000	0.998	0.002
S00.0 Superficial injury of scalp	0.002	0.998	0.000
C92.9 Myeloid leukaemia, unspecified	0.002	0.998	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.002	0.998	0.000
C92.7 Other myeloid leukaemia	0.002	0.998	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.002	0.998	0.000
C92.5 Acute myelomonocytic leukaemia	0.002	0.998	0.000
C92.4 Acute promyelocytic leukaemia	0.002	0.998	0.000
C92.3 Myeloid sarcoma	0.002	0.998	0.000
C92.2 Subacute myeloid leukaemia	0.002	0.998	0.000
C93.1 Chronic monocytic leukaemia	0.002	0.998	0.000
C95.9 Leukaemia, unspecified	0.002	0.998	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.002	0.998	0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.002	0.998	0.000
F02.2 Dementia in Huntington's disease	0.002	0.998	0.000
F02.1 Dementia in Creutzfeldt-Jakob disease	0.002	0.998	0.000
K35.8 Acute appendicitis, other and unspecified	0.000	0.998	0.002
D68.8 Other specified coagulation defects	0.002	0.998	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.002	0.998	0.000
H93.9 Disorder of ear, unspecified	0.002	0.998	0.000
R73.9 Hyperglycaemia, unspecified	0.000	0.998	0.002
C88 Malignant immunoproliferative diseases	0.002	0.998	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.002	0.998	0.000
D68.5 Primary Thrombophilia	0.002	0.998	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.002	0.998	0.000
N28.8 Other specified disorders of kidney and ureter	0.002	0.998	0.000
C18 Malignant neoplasm of colon	0.002	0.998	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
C94 Other leukaemias of specified cell type	0.002	0.998	0.000
C86 Other specified types of T/NK-cell lymphoma	0.002	0.998	0.000
S92.00 Fracture of calcaneus (closed)	0.000	0.998	0.002
G25.2 Other specified forms of tremor	0.002	0.998	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.002	0.998	0.000
C84.0 Mycosis fungoides	0.002	0.998	0.000
C92.0 Acute myeloid leukaemia	0.002	0.998	0.000
E21.0 Primary hyperparathyroidism	0.002	0.998	0.000
J32.4 Chronic pansinusitis	0.000	0.998	0.002
J69.0 Pneumonitis due to food and vomit	0.002	0.998	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.002	0.998	0.000
F05.8 Other delirium	0.002	0.998	0.000
D69 Purpura and other haemorrhagic conditions	0.002	0.998	0.000
G24 Dystonia	0.002	0.998	0.000
C83.0 Small cell (diffuse)	0.002	0.998	0.000
E83.1 Disorders of iron metabolism	0.002	0.998	0.000
J32.3 Chronic sphenoidal sinusitis	0.000	0.998	0.002
C18.8 Overlapping lesion of colon	0.002	0.998	0.000
C84.4 Peripheral T-cell lymphoma	0.002	0.998	0.000
F05.1 Delirium superimposed on dementia	0.002	0.998	0.000
F05.0 Delirium not superimposed on dementia, so described	0.002	0.998	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.002	0.998	0.000
D68.2 Hereditary deficiency of other clotting factors	0.002	0.998	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.002	0.998	0.000
F09 Unspecified organic or symptomatic mental disorder	0.002	0.998	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.002	0.998	0.000
S02.10 Fracture of base of skull (closed)	0.002	0.998	0.000
C93.9 Monocytic leukaemia, unspecified	0.002	0.998	0.000
C93.7 Other monocytic leukaemia	0.002	0.998	0.000
C93.3 Juvenile myelomonocytic leukaemia	0.002	0.998	0.000
C93.2 Subacute monocytic leukaemia	0.002	0.998	0.000
C93.0 Acute monocytic leukaemia	0.002	0.998	0.000
C95.7 Other leukaemia of unspecified cell type	0.002	0.998	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.002	0.998	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.002	0.998	0.000
C95.0 Acute leukaemia of unspecified cell type	0.002	0.998	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.002	0.998	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.002	0.998	0.000
G25.5 Other chorea	0.002	0.998	0.000
G25.4 Drug-induced chorea	0.002	0.998	0.000
G25.1 Drug-induced tremor	0.002	0.998	0.000
D68.6 Other Thrombophilia	0.002	0.998	0.000
D68.4 Acquired coagulation factor deficiency	0.002	0.998	0.000
D68.1 Hereditary factor XI deficiency	0.002	0.998	0.000
E66.8 Other obesity	0.002	0.998	0.000
G25.0 Essential tremor	0.002	0.998	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.002	0.998	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.002	0.998	0.000
G24.3 Spasmodic torticollis	0.002	0.998	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.002	0.998	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.002	0.998	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.002	0.998	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.002	0.998	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations