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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs379440
log Bayes Factor = 2.52889
Chromosome 5   position 111,693,371  (GRCh37) Explore rs379440 on Ensembl!
Variant rs379440 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M20-M25 Other joint disorders
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.996 0.004 0.000
M50-M54 Other dorsopathies
0.994 0.006 0.000
M35 Other systemic involvement of connective tissue
0.992 0.008 0.000
M54 Dorsalgia
0.989 0.011 0.000
M35.3 Polymyalgia rheumatica
0.988 0.012 0.000
M54.5 Low back pain
0.976 0.024 0.000
M54.59 Low back pain (Site unspecified)
0.955 0.045 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.955 0.045 0.000
M54.1 Radiculopathy
0.936 0.064 0.000
M25 Other joint disorders, not elsewhere classified
0.927 0.073 0.000
M86-M90 Other osteopathies
0.890 0.110 0.000
M25.8 Other specified joint disorders
0.875 0.125 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.867 0.133 0.000
M54.57 Low back pain (Lumbosacral region)
0.862 0.138 0.000
M54.16 Radiculopathy (Lumbar region)
0.860 0.140 0.000
M24 Other specific joint derangements
0.844 0.156 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.841 0.159 0.000
M23 Internal derangement of knee
0.838 0.162 0.000
M33 Dermatopolymyositis
0.832 0.168 0.000
M60-M63 Disorders of muscles
0.829 0.171 0.000
M23.3 Other meniscus derangements
0.822 0.178 0.000
M15-M19 Arthrosis
0.820 0.180 0.000
M51 Other intervertebral disk disorders
0.820 0.180 0.000
M25.3 Other instability of joint
0.818 0.182 0.000
M35.1 Other overlap syndromes
0.816 0.184 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.812 0.188 0.000
M22 Disorders of patella
0.801 0.199 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.792 0.208 0.000
M00-M03 Infectious arthropathies
0.792 0.208 0.000
M91-M94 Chondropathies
0.790 0.210 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.789 0.211 0.000
M80-M85 Disorders of bone density and structure
0.785 0.215 0.000
M19 Other arthrosis
0.780 0.220 0.000
M54.9 Dorsalgia, unspecified
0.766 0.234 0.000
M54.4 Lumbago with sciatica
0.763 0.237 0.000
M31 Other necrotising vasculopathies
0.761 0.239 0.000
M25.84 Other specified joint disorders (Hand)
0.758 0.242 0.000
M53 Other dorsopathies, not elsewhere classified
0.755 0.245 0.000
M54.8 Other dorsalgia
0.755 0.245 0.000
M40-M43 Deforming dorsopathies
0.753 0.247 0.000
M32 Systemic lupus erythematosus
0.751 0.248 0.000
M86 Osteomyelitis
0.751 0.249 0.000
M54.50 Low back pain (Multiple sites in spine)
0.749 0.250 0.000
M54.56 Low back pain (Lumbar region)
0.744 0.256 0.000
M54.19 Radiculopathy (Site unspecified)
0.741 0.259 0.000
M99 Biomechanical lesions, not elsewhere classified
0.741 0.259 0.000
M35.7 Hypermobility syndrome
0.735 0.264 0.000
M50 Cervical disk disorders
0.735 0.264 0.000
M54.12 Radiculopathy (Cervical region)
0.731 0.269 0.000
M89 Other disorders of bone
0.729 0.271 0.000
M19.0 Primary arthrosis of other joints
0.727 0.273 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.715 0.285 0.000
M30 Polyarteritis nodosa and related conditions
0.715 0.285 0.000
M51.8 Other specified intervertebral disk disorders
0.714 0.286 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.713 0.287 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.712 0.288 0.000
M35.8 Other specified systemic involvement of connective tissue
0.712 0.288 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.712 0.288 0.000
M35.5 Multifocal fibrosclerosis
0.712 0.288 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.712 0.288 0.000
M35.2 Behcet's disease
0.712 0.288 0.000
M54.0 Panniculitis affecting regions of neck and back
0.709 0.291 0.000
M95.2 Other acquired deformity of head
0.709 0.291 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.703 0.297 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.702 0.298 0.000
M21 Other acquired deformities of limbs
0.701 0.298 0.000
M54.55 Low back pain (Thoracolumbar region)
0.700 0.300 0.000
M54.54 Low back pain-Thoracic
0.700 0.300 0.000
M54.53 Low back pain-Cervicothoracic
0.700 0.300 0.000
M54.52 Low back pain-Cervical
0.700 0.300 0.000
M54.51 Low back pain-Occipit-atl-axl
0.700 0.300 0.000
M25.37 Other instability of joint (Ankle and foot)
0.699 0.301 0.000
M50.2 Other cervical disk displacement
0.698 0.302 0.000
M25.88 Other specified joint disorders (Other)
0.697 0.303 0.000
M95.0 Acquired deformity of nose
0.694 0.306 0.000
M25.86 Other specified joint disorders (Lower leg)
0.693 0.307 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.685 0.315 0.000
M34 Systemic sclerosis
0.685 0.315 0.000
M22.8 Other disorders of patella
0.680 0.320 0.000
M33.2 Polymyositis
0.679 0.321 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.679 0.321 0.000
M87 Osteonecrosis
0.677 0.323 0.000
M18 Arthrosis of first carpometacarpal joint
0.674 0.326 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.671 0.329 0.000
M54.15 Radiculopathy (Thoracolumbar region)
0.671 0.329 0.000
M54.14 Radiculopathy (Thoracic region)
0.671 0.329 0.000
M54.13 Radiculopathy (Cervicothoracic region)
0.671 0.329 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.671 0.329 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.671 0.329 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.671 0.329 0.000
M19.9 Arthrosis, unspecified
0.670 0.330 0.000
M25.4 Effusion of joint
0.669 0.331 0.000
M22.4 Chondromalacia patellae
0.667 0.333 0.000
M24.2 Disorder of ligament
0.667 0.333 0.000
M25.9 Joint disorder, unspecified
0.666 0.334 0.000
M25.34 Other instability of joint (Hand)
0.665 0.335 0.000
M25.2 Flail joint
0.665 0.335 0.000
M25.1 Fistula of joint
0.665 0.335 0.000
M62 Other disorders of muscle
0.661 0.339 0.000
M60 Myositis
0.661 0.339 0.000
M25.5 Pain in joint
0.657 0.343 0.000
M35.0 Sicca syndrome [Sjogren]
0.657 0.343 0.000
M88 Paget's disease of bone [osteitis deformans]
0.656 0.344 0.000
M45-M49 Spondylopathies
0.655 0.345 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.653 0.347 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.653 0.347 0.000
M86.9 Osteomyelitis, unspecified
0.651 0.349 0.000
M33.1 Other dermatomyositis
0.651 0.349 0.000
M85 Other disorders of bone density and structure
0.650 0.350 0.000
M00 Pyogenic arthritis
0.646 0.354 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.644 0.356 0.000
M24.1 Other articular cartilage disorders
0.642 0.358 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.641 0.358 0.000
M54.6 Pain in thoracic spine
0.641 0.359 0.000
M94 Other disorders of cartilage
0.636 0.364 0.000
M54.3 Sciatica
0.633 0.367 0.000
M25.0 Haemarthrosis
0.632 0.367 0.000
M20 Acquired deformities of fingers and toes
0.630 0.370 0.000
M25.89 Other specified joint disorders (Site unspecified)
0.627 0.373 0.000
M25.83 Other specified joint disorders (Forearm)
0.627 0.373 0.000
M25.82 Other specified joint disorders (Upper arm)
0.627 0.373 0.000
M25.80 Other specified joint disorders (Multiple sites)
0.627 0.373 0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate
0.622 0.378 0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified
0.622 0.378 0.000
M96.5 Postradiation scoliosis
0.622 0.378 0.000
M96.4 Postsurgical lordosis
0.622 0.378 0.000
M96.3 Postlaminectomy kyphosis
0.622 0.378 0.000
M96.2 Postradiation kyphosis
0.622 0.378 0.000
M65-M68 Disorders of synovium and tendon
0.622 0.378 0.000
M19.94 Arthrosis, unspecified (Hand)
0.621 0.379 0.000
M90 Osteopathies in diseases classified elsewhere
0.617 0.382 0.000
M24.0 Loose body in joint
0.613 0.386 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.611 0.388 0.000
M81 Osteoporosis without pathological fracture
0.611 0.389 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.610 0.390 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.609 0.391 0.000
M24.9 Joint derangement, unspecified
0.605 0.395 0.000
M24.7 Protrusio acetabuli
0.605 0.395 0.000
M24.6 Ankylosis of joint
0.605 0.395 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.605 0.395 0.000
M95.9 Acquired deformity of musculoskeletal system, unspecified
0.603 0.397 0.000
M95.8 Other specified acquired deformities of musculoskeletal system
0.603 0.397 0.000
M95.5 Acquired deformity of pelvis
0.603 0.397 0.000
M95.4 Acquired deformity of chest and rib
0.603 0.397 0.000
M95.3 Acquired deformity of neck
0.603 0.397 0.000
M95.1 Cauliflower ear
0.603 0.397 0.000
M23.9 Internal derangement of knee, unspecified
0.601 0.399 0.000
M23.1 Discoid meniscus (congenital)
0.601 0.399 0.000
M23.0 Cystic meniscus
0.601 0.399 0.000
M89.8 Other specified disorders of bone
0.599 0.401 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.599 0.401 0.000
M33.9 Dermatopolymyositis, unspecified
0.597 0.403 0.000
M33.0 Juvenile dermatomyositis
0.597 0.403 0.000
M23.5 Chronic instability of knee
0.595 0.404 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.594 0.405 0.000
M61 Calcification and ossification of muscle
0.594 0.405 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.591 0.409 0.000
M25.50 Pain in joint (Multiple sites)
0.591 0.409 0.000
M40 Kyphosis and lordosis
0.590 0.410 0.000
M54.2 Cervicalgia
0.590 0.410 0.000
M23.37 Other meniscus derangements-Capsular lig
0.589 0.411 0.000
M15 Polyarthrosis
0.588 0.412 0.000
M51.3 Other specified intervertebral disk degeneration
0.588 0.412 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.588 0.412 0.000
M51.4 Schmorl's nodes
0.588 0.412 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.587 0.413 0.000
M99.5 Intervertebral disk stenosis of neural canal
0.587 0.413 0.000
M19.09 Primary arthrosis of other joints (Site unspecified)
0.587 0.413 0.000
M25.39 Other instability of joint (Site unspecified)
0.586 0.413 0.000
M25.38 Other instability of joint (Other)
0.586 0.413 0.000
M25.36 Other instability of joint (Lower leg)
0.586 0.413 0.000
M25.35 Other instability of joint (Pelvic region and thigh)
0.586 0.413 0.000
M25.33 Other instability of joint (Forearm)
0.586 0.413 0.000
M25.32 Other instability of joint (Upper arm)
0.586 0.413 0.000
M25.31 Other instability of joint (Shoulder region)
0.586 0.413 0.000
M25.30 Other instability of joint (Multiple sites)
0.586 0.413 0.000
M54.89 Other dorsalgia (Site unspecified)
0.586 0.414 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.584 0.416 0.000
M25.56 Pain in joint (Lower leg)
0.581 0.419 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.581 0.419 0.000
M24.5 Contracture of joint
0.580 0.420 0.000
M31.6 Other giant cell arteritis
0.580 0.420 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.580 0.420 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.578 0.422 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.575 0.424 0.000
M92 Other juvenile osteochondrosis
0.574 0.426 0.000
M22.1 Recurrent subluxation of patella
0.574 0.426 0.000
M22.9 Disorder of patella, unspecified
0.574 0.426 0.000
M22.0 Recurrent dislocation of patella
0.574 0.426 0.000
M41 Scoliosis
0.571 0.429 0.000
M19.03 Primary arthrosis of other joints (Forearm)
0.569 0.431 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.568 0.432 0.000
M02 Reactive arthropathies
0.568 0.432 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.568 0.432 0.000
M82 Osteoporosis in diseases classified elsewhere
0.568 0.432 0.000
M93 Other osteochondropathies
0.566 0.434 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.566 0.434 0.000
M25.7 Osteophyte
0.565 0.435 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.564 0.436 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.563 0.437 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.563 0.437 0.000
M83 Adult osteomalacia
0.563 0.437 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.561 0.439 0.000
M19.8 Other specified arthrosis
0.559 0.441 0.000
M19.2 Other secondary arthrosis
0.559 0.441 0.000
M80 Osteoporosis with pathological fracture
0.558 0.442 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.553 0.447 0.000
M51.2 Other specified intervertebral disk displacement
0.551 0.449 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.549 0.451 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.549 0.451 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.549 0.451 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.549 0.451 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.549 0.451 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.549 0.451 0.000
M25.53 Pain in joint (Forearm)
0.548 0.452 0.000
M85.8 Other specified disorders of bone density and structure
0.547 0.453 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.547 0.453 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.547 0.453 0.000
M54.44 Lumbago with sciatica-Thoracic
0.547 0.453 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.547 0.453 0.000
M54.42 Lumbago with sciatica-Cervical
0.547 0.453 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.547 0.453 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.547 0.453 0.000
M31.9 Necrotising vasculopathy, unspecified
0.546 0.454 0.000
M31.8 Other specified necrotising vasculopathies
0.546 0.454 0.000
M31.7 Microscopic polyangiitis
0.546 0.454 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.546 0.454 0.000
M31.2 Lethal midline granuloma
0.546 0.454 0.000
M31.1 Thrombotic microangiopathy
0.546 0.454 0.000
M31.0 Hypersensitivity angiitis
0.546 0.454 0.000
M89.9 Disorder of bone, unspecified
0.544 0.456 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.543 0.457 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.543 0.457 0.000
M20.4 Other hammer toe(s) (acquired)
0.542 0.458 0.000
M53.9 Dorsopathy, unspecified
0.541 0.459 0.000
M53.8 Other specified dorsopathies
0.541 0.459 0.000
M53.2 Spinal instabilities
0.541 0.459 0.000
M53.1 Cervicobrachial syndrome
0.541 0.459 0.000
M53.0 Cervicocranial syndrome
0.541 0.459 0.000
M62.8 Other specified disorders of muscle
0.541 0.459 0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)
0.541 0.459 0.000
M54.87 Other dorsalgia (Lumbosacral region)
0.541 0.459 0.000
M54.86 Other dorsalgia (Lumbar region)
0.541 0.459 0.000
M54.85 Other dorsalgia (Thoracolumbar region)
0.541 0.459 0.000
M54.84 Other dorsalgia (Thoracic region)
0.541 0.459 0.000
M54.83 Other dorsalgia (Cervicothoracic region)
0.541 0.459 0.000
M54.82 Other dorsalgia (Cervical region)
0.541 0.459 0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)
0.541 0.459 0.000
M54.80 Other dorsalgia (Multiple sites in spine)
0.541 0.459 0.000
M00.9 Pyogenic arthritis, unspecified
0.541 0.459 0.000
M42 Spinal osteochondrosis
0.540 0.460 0.000
M20.0 Deformity of finger(s)
0.539 0.460 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.539 0.461 0.000
M32.8 Other forms of systemic lupus erythematosus
0.539 0.461 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.539 0.461 0.000
M22.3 Other derangements of patella
0.538 0.461 0.000
M86.8 Other osteomyelitis
0.538 0.461 0.000
M86.6 Other chronic osteomyelitis
0.538 0.461 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.538 0.461 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.538 0.461 0.000
M86.3 Chronic multifocal osteomyelitis
0.538 0.461 0.000
M86.2 Subacute osteomyelitis
0.538 0.461 0.000
M86.1 Other acute osteomyelitis
0.538 0.461 0.000
M86.0 Acute haematogenous osteomyelitis
0.538 0.461 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.538 0.462 0.000
M21.2 Flexion deformity
0.535 0.465 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.534 0.466 0.000
M19.1 Posttraumatic arthrosis of other joints
0.533 0.467 0.000
M54.37 Sciatica (Lumbosacral region)
0.532 0.468 0.000
M99.9 Biomechanical lesion, unspecified
0.531 0.469 0.000
M99.8 Other biomechanical lesions
0.531 0.469 0.000
M99.7 Connective tissue and disk stenosis of intervertebral foramina
0.531 0.469 0.000
M99.6 Osseous and subluxation stenosis of intervertebral foramina
0.531 0.469 0.000
M99.4 Connective tissue stenosis of neural canal
0.531 0.469 0.000
M99.3 Osseous stenosis of neural canal
0.531 0.469 0.000
M99.2 Subluxation stenosis of neural canal
0.531 0.469 0.000
M99.1 Subluxation complex (vertebral)
0.531 0.469 0.000
M99.0 Segmental and somatic dysfunction
0.531 0.469 0.000
M25.40 Effusion of joint (Multiple sites)
0.531 0.469 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.530 0.470 0.000
M50.9 Cervical disk disorder, unspecified
0.527 0.473 0.000
M50.8 Other cervical disk disorders
0.527 0.473 0.000
M94.8 Other specified disorders of cartilage
0.526 0.474 0.000
M21.4 Flat foot [pes planus] (acquired)
0.525 0.475 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.523 0.477 0.000
M89.6 Osteopathy after poliomyelitis
0.522 0.477 0.000
M89.5 Osteolysis
0.522 0.477 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.522 0.477 0.000
M89.3 Hypertrophy of bone
0.522 0.477 0.000
M89.2 Other disorders of bone development and growth
0.522 0.477 0.000
M89.1 Epiphyseal arrest
0.522 0.477 0.000
M89.0 Algoneurodystrophy
0.522 0.477 0.000
M19.08 Primary arthrosis of other joints (Other)
0.521 0.479 0.000
M19.06 Primary arthrosis of other joints-Lower leg
0.521 0.479 0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)
0.521 0.479 0.000
M19.02 Primary arthrosis of other joints (Upper arm)
0.521 0.479 0.000
M19.00 Primary arthrosis of other joints (Multiple sites)
0.521 0.479 0.000
M20.3 Other deformity of hallux (acquired)
0.516 0.483 0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)
0.516 0.484 0.000
M60.0 Infective myositis
0.516 0.484 0.000
M21.1 Varus deformity, not elsewhere classified
0.515 0.484 0.000
M24.23 Disorder of ligament (Forearm)
0.513 0.486 0.000
M89.87 Other specified disorders of bone (Ankle and foot)
0.513 0.487 0.000
M30.8 Other conditions related to polyarteritis nodosa
0.512 0.487 0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.512 0.487 0.000
M30.2 Juvenile polyarteritis
0.512 0.487 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.512 0.487 0.000
M30.0 Polyarteritis nodosa
0.512 0.487 0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.512 0.487 0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.512 0.487 0.000
M36.3 Arthropathy in other blood disorders
0.512 0.487 0.000
M36.2 Haemophilic arthropathy
0.512 0.487 0.000
M36.1 Arthropathy in neoplastic disease
0.512 0.487 0.000
M36.0 Dermato(poly)myositis in neoplastic disease
0.512 0.487 0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.510 0.490 0.000
M24.24 Disorder of ligament (Hand)
0.510 0.490 0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)
0.509 0.491 0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)
0.509 0.491 0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)
0.509 0.491 0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)
0.509 0.491 0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)
0.509 0.491 0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)
0.509 0.491 0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)
0.509 0.491 0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)
0.509 0.491 0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)
0.509 0.491 0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)
0.509 0.491 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.508 0.492 0.000
M87.9 Osteonecrosis, unspecified
0.507 0.493 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.507 0.493 0.000
M60.9 Myositis, unspecified
0.506 0.494 0.000
M87.2 Osteonecrosis due to previous trauma
0.505 0.495 0.000
M46 Other inflammatory spondylopathies
0.504 0.496 0.000
M21.9 Acquired deformity of limb, unspecified
0.503 0.497 0.000
M21.8 Other specified acquired deformities of limbs
0.503 0.497 0.000
M21.7 Unequal limb length (acquired)
0.503 0.497 0.000
M19.04 Primary arthrosis of other joints (Hand)
0.503 0.497 0.000
M23.4 Loose body in knee
0.502 0.498 0.000
M85.6 Other cyst of bone
0.502 0.498 0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.501 0.499 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.501 0.499 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.497 0.503 0.000
M25.52 Pain in joint (Upper arm)
0.497 0.503 0.000
M34.1 CR(E)ST syndrome
0.496 0.503 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.493 0.506 0.000
M81.9 Osteoporosis, unspecified
0.493 0.507 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.491 0.509 0.000
M34.8 Other forms of systemic sclerosis
0.491 0.509 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.491 0.509 0.000
M34.0 Progressive systemic sclerosis
0.491 0.509 0.000
M25.59 Pain in joint (Site unspecified)
0.489 0.511 0.000
M88.9 Paget's disease of bone, unspecified
0.488 0.512 0.000
M43 Other deforming dorsopathies
0.487 0.513 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.486 0.514 0.000
M24.01 Loose body in joint (Shoulder region)
0.486 0.514 0.000
M87.8 Other osteonecrosis
0.486 0.514 0.000
M87.3 Other secondary osteonecrosis
0.486 0.514 0.000
M87.1 Osteonecrosis due to drugs
0.486 0.514 0.000
M87.0 Idiopathic aseptic necrosis of bone
0.486 0.514 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.483 0.517 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.483 0.517 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.483 0.517 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.483 0.517 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.481 0.519 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.481 0.519 0.000
M25.49 Effusion of joint (Site unspecified)
0.480 0.520 0.000
M25.48 Effusion of joint (Other)
0.480 0.520 0.000
M25.44 Effusion of joint (Hand)
0.480 0.520 0.000
M25.43 Effusion of joint (Forearm)
0.480 0.520 0.000
M25.42 Effusion of joint (Upper arm)
0.480 0.520 0.000
M25.41 Effusion of joint (Shoulder region)
0.480 0.520 0.000
M21.0 Valgus deformity, not elsewhere classified
0.479 0.521 0.000
M24.29 Disorder of ligament (Site unspecified)
0.478 0.521 0.000
M24.28 Disorder of ligament (Other)
0.478 0.521 0.000
M24.26 Disorder of ligament (Lower leg)
0.478 0.521 0.000
M24.25 Disorder of ligament (Pelvic region and thigh)
0.478 0.521 0.000
M24.22 Disorder of ligament (Upper arm)
0.478 0.521 0.000
M24.21 Disorder of ligament (Shoulder region)
0.478 0.521 0.000
M24.20 Disorder of ligament (Multiple sites)
0.478 0.521 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.478 0.522 0.000
M25.99 Joint disorder, unspecified (Site unspecified)
0.477 0.523 0.000
M25.98 Joint disorder, unspecified (Other)
0.477 0.523 0.000
M25.97 Joint disorder, unspecified (Ankle and foot)
0.477 0.523 0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)
0.477 0.523 0.000
M25.94 Joint disorder, unspecified (Hand)
0.477 0.523 0.000
M25.93 Joint disorder, unspecified (Forearm)
0.477 0.523 0.000
M25.92 Joint disorder, unspecified (Upper arm)
0.477 0.523 0.000
M25.91 Joint disorder, unspecified (Shoulder region)
0.477 0.523 0.000
M25.90 Joint disorder, unspecified (Multiple sites)
0.477 0.523 0.000
M99.53 Intervertebral disc stenosis of neural canal (Lumbar region)
0.477 0.523 0.000
M25.19 Fistula of joint (Site unspecified)
0.477 0.523 0.000
M25.18 Fistula of joint (Other)
0.477 0.523 0.000
M25.17 Fistula of joint (Ankle and foot)
0.477 0.523 0.000
M25.16 Fistula of joint (Lower leg)
0.477 0.523 0.000
M25.15 Fistula of joint (Pelvic region and thigh)
0.477 0.523 0.000
M25.14 Fistula of joint (Hand)
0.477 0.523 0.000
M25.13 Fistula of joint (Forearm)
0.477 0.523 0.000
M25.12 Fistula of joint (Upper arm)
0.477 0.523 0.000
M25.11 Fistula of joint (Shoulder region)
0.477 0.523 0.000
M25.10 Fistula of joint (Multiple sites)
0.477 0.523 0.000
M25.29 Flail joint (Site unspecified)
0.477 0.523 0.000
M25.28 Flail joint (Other)
0.477 0.523 0.000
M25.27 Flail joint (Ankle and foot)
0.477 0.523 0.000
M25.26 Flail joint (Lower leg)
0.477 0.523 0.000
M25.25 Flail joint (Pelvic region and thigh)
0.477 0.523 0.000
M25.24 Flail joint (Hand)
0.477 0.523 0.000
M25.23 Flail joint (Forearm)
0.477 0.523 0.000
M25.22 Flail joint (Upper arm)
0.477 0.523 0.000
M25.21 Flail joint (Shoulder region)
0.477 0.523 0.000
M25.20 Flail joint (Multiple sites)
0.477 0.523 0.000
M62.9 Disorder of muscle, unspecified
0.474 0.526 0.000
M62.6 Muscle strain
0.474 0.526 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.474 0.526 0.000
M62.4 Contracture of muscle
0.474 0.526 0.000
M62.3 Immobility syndrome (paraplegic)
0.474 0.526 0.000
M62.2 Ischaemic infarction of muscle
0.474 0.526 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.474 0.526 0.000
M62.0 Diastasis of muscle
0.474 0.526 0.000
M60.8 Other myositis
0.474 0.526 0.000
M60.2 Foreign body granuloma of soft tissue, not elsewhere classified
0.474 0.526 0.000
M60.1 Interstitial myositis
0.474 0.526 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.474 0.526 0.000
M40.2 Other and unspecified kyphosis
0.473 0.527 0.000
M31.3 Wegener's granulomatosis
0.472 0.528 0.000
M25.58 Pain in joint (Other)
0.471 0.529 0.000
M88.8 Paget's disease of other bones
0.470 0.530 0.000
M88.0 Paget's disease of skull
0.470 0.530 0.000
M49 Spondylopathies in diseases classified elsewhere
0.470 0.530 0.000
M48 Other spondylopathies
0.468 0.532 0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)
0.468 0.532 0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)
0.468 0.532 0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)
0.468 0.532 0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)
0.468 0.532 0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)
0.468 0.532 0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)
0.468 0.532 0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)
0.468 0.532 0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)
0.468 0.532 0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)
0.468 0.532 0.000
M25.71 Osteophyte (Shoulder region)
0.468 0.532 0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)
0.467 0.533 0.000
M86.98 Osteomyelitis, unspecified (Other)
0.467 0.533 0.000
M86.96 Osteomyelitis, unspecified (Lower leg)
0.467 0.533 0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)
0.467 0.533 0.000
M86.94 Osteomyelitis, unspecified (Hand)
0.467 0.533 0.000
M86.93 Osteomyelitis, unspecified (Forearm)
0.467 0.533 0.000
M86.92 Osteomyelitis, unspecified (Upper arm)
0.467 0.533 0.000
M86.91 Osteomyelitis, unspecified (Shoulder region)
0.467 0.533 0.000
M86.90 Osteomyelitis, unspecified (Multiple sites)
0.467 0.533 0.000
M85.9 Disorder of bone density and structure, unspecified
0.466 0.534 0.000
M85.5 Aneurysmal bone cyst
0.466 0.534 0.000
M85.4 Solitary bone cyst
0.466 0.534 0.000
M85.3 Osteitis condensans
0.466 0.534 0.000
M85.2 Hyperostosis of skull
0.466 0.534 0.000
M85.1 Skeletal fluorosis
0.466 0.534 0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)
0.465 0.534 0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)
0.465 0.535 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.464 0.536 0.000
M84 Disorders of continuity of bone
0.464 0.536 0.000
M21.6 Other acquired deformities of ankle and foot
0.463 0.537 0.000
M00.8 Arthritis and polyarthritis due to other specified bacterial agents
0.463 0.537 0.000
M00.2 Other streptococcal arthritis and polyarthritis
0.463 0.537 0.000
M00.1 Pneumococcal arthritis and polyarthritis
0.463 0.537 0.000
M00.0 Staphylococcal arthritis and polyarthritis
0.463 0.537 0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)
0.462 0.538 0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)
0.462 0.538 0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)
0.462 0.538 0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)
0.462 0.538 0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)
0.462 0.538 0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)
0.462 0.538 0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)
0.462 0.538 0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)
0.462 0.538 0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)
0.462 0.538 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.462 0.538 0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s
0.461 0.539 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.460 0.540 0.000
M24.18 Other articular cartilage disorders (Other)
0.460 0.540 0.000
M24.14 Other articular cartilage disorders (Hand)
0.460 0.540 0.000
M24.12 Other articular cartilage disorders (Upper arm)
0.460 0.540 0.000
M24.10 Other articular cartilage disorders (Multiple sites)
0.460 0.540 0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)
0.460 0.540 0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)
0.460 0.540 0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp
0.460 0.540 0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn
0.460 0.540 0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.460 0.540 0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.460 0.540 0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.460 0.540 0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)
0.460 0.540 0.000
M54.69 Pain in thoracic spine-Site unspe
0.459 0.540 0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ
0.459 0.540 0.000
M54.67 Pain in thoracic spine-Lumbosacral
0.459 0.540 0.000
M54.66 Pain in thoracic spine-Lumbar
0.459 0.540 0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)
0.459 0.540 0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)
0.459 0.540 0.000
M54.62 Pain in thoracic spine-Cervical
0.459 0.540 0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl
0.459 0.540 0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)
0.459 0.540 0.000
M94.9 Disorder of cartilage, unspecified
0.456 0.544 0.000
M94.3 Chondrolysis
0.456 0.544 0.000
M94.2 Chondromalacia
0.456 0.544 0.000
M94.1 Relapsing polychondritis
0.456 0.544 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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