TreeWAS – Variant ID: rs3801387

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S52.50 Fracture of lower end of radius (closed)	0.000	0.000	1.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.000	0.000	1.000
S52.6 Fracture of lower end of both ulna and radius	0.000	0.000	1.000
S52.5 Fracture of lower end of radius	0.000	0.001	0.999
S52 Fracture of forearm	0.000	0.001	0.999
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.002	0.998
M81.9 Osteoporosis, unspecified	0.000	0.051	0.949
S52.61 Fracture of lower end of both ulna and radius (open)	0.000	0.069	0.931
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.110	0.890
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.000	0.119	0.881
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.119	0.881
S52.4 Fracture of shafts of both ulna and radius	0.000	0.214	0.786
S52.8 Fracture of other parts of forearm	0.000	0.238	0.762
S52.7 Multiple fractures of forearm	0.000	0.267	0.733
S52.3 Fracture of shaft of radius	0.000	0.268	0.732
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.279	0.721
S52.9 Fracture of forearm, part unspecified	0.000	0.284	0.716
M81 Osteoporosis without pathological fracture	0.000	0.317	0.683
S52.51 Fracture of lower end of radius (open)	0.000	0.319	0.681
S52.1 Fracture of upper end of radius	0.000	0.319	0.681
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.320	0.680
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.320	0.680
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.320	0.680
S52.0 Fracture of upper end of ulna	0.000	0.347	0.653
S82 Fracture of lower leg, including ankle	0.000	0.359	0.641
S82.0 Fracture of patella	0.000	0.360	0.640
S82.00 Fracture of patella (closed)	0.000	0.361	0.639
S52.40 Fracture of shafts of both ulna and radius (closed)	0.000	0.367	0.633
S82.8 Fractures of other parts of lower leg	0.000	0.384	0.616
S82.80 Fractures of other parts of lower leg (closed)	0.000	0.396	0.604
S82.5 Fracture of medial malleolus	0.000	0.407	0.593
S52.80 Fracture of other parts of forearm (closed)	0.000	0.407	0.593
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.417	0.583
S82.1 Fracture of upper end of tibia	0.000	0.428	0.572
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.430	0.569
S52.41 Fracture of shafts of both ulna and radius (open)	0.000	0.437	0.563
S82.50 Fracture of medial malleolus (closed)	0.000	0.438	0.561
M81.98 Osteoporosis, unspecified (Other)	0.000	0.449	0.551
S52.81 Fracture of other parts of forearm (open)	0.000	0.453	0.546
S52.70 Multiple fractures of forearm (closed)	0.000	0.458	0.542
S52.30 Fracture of shaft of radius (closed)	0.000	0.459	0.541
M81.2 Osteoporosis of disuse	0.000	0.461	0.539
S52.01 Fracture of upper end of ulna (open)	0.000	0.467	0.533
M81.4 Drug-induced osteoporosis	0.000	0.469	0.531
S82.6 Fracture of lateral malleolus	0.000	0.469	0.531
S52.71 Multiple fractures of forearm (open)	0.000	0.475	0.525
S52.31 Fracture of shaft of radius (open)	0.000	0.475	0.525
S52.2 Fracture of shaft of ulna	0.000	0.476	0.524
S82.01 Fracture of patella (open)	0.000	0.479	0.521
S82.10 Fracture of upper end of tibia (closed)	0.000	0.480	0.520
M81.0 Postmenopausal osteoporosis	0.000	0.482	0.518
S82.7 Multiple fractures of lower leg	0.000	0.483	0.517
S52.91 Fracture of forearm, part unspecified (open)	0.000	0.486	0.513
S52.90 Fracture of forearm, part unspecified (closed)	0.000	0.486	0.513
S82.4 Fracture of fibula alone	0.000	0.492	0.508
S82.3 Fracture of lower end of tibia	0.000	0.506	0.494
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.506	0.494
M81.8 Other osteoporosis	0.000	0.510	0.490
M81.6 Localised osteoporosis [Lequesne]	0.000	0.510	0.490
M81.5 Idiopathic osteoporosis	0.000	0.510	0.490
M81.1 Postoophorectomy osteoporosis	0.000	0.510	0.490
S52.11 Fracture of upper end of radius (open)	0.000	0.512	0.488
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.540	0.460
S82.9 Fracture of lower leg, part unspecified	0.000	0.540	0.459
S52.10 Fracture of upper end of radius (closed)	0.000	0.547	0.453
S82.60 Fracture of lateral malleolus (closed)	0.000	0.547	0.453
S82.86 Maisonneuve's fracture	0.000	0.558	0.442
M81.20 Osteoporosis of disuse (Multiple sites)	0.000	0.563	0.436
S82.70 Multiple fractures of lower leg (closed)	0.000	0.572	0.428
S82.11 Fracture of upper end of tibia (open)	0.000	0.581	0.419
S82.51 Fracture of medial malleolus (open)	0.000	0.585	0.415
S82.40 Fracture of fibula alone (closed)	0.000	0.587	0.413
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.000	0.600	0.399
S82.30 Fracture of lower end of tibia (closed)	0.000	0.602	0.398
S82.81 Fractures of other parts of lower leg (open)	0.000	0.611	0.389
M81.29 Osteoporosis of disuse (Site unspecified)	0.000	0.613	0.387
M81.28 Osteoporosis of disuse (Other)	0.000	0.613	0.387
M81.27 Osteoporosis of disuse (Ankle and foot)	0.000	0.613	0.387
M81.26 Osteoporosis of disuse (Lower leg)	0.000	0.613	0.387
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.000	0.613	0.387
M81.24 Osteoporosis of disuse (Hand)	0.000	0.613	0.387
M81.23 Osteoporosis of disuse (Forearm)	0.000	0.613	0.387
M81.22 Osteoporosis of disuse (Upper arm)	0.000	0.613	0.387
M81.21 Osteoporosis of disuse (Shoulder region)	0.000	0.613	0.387
M81.48 Drug-induced osteoporosis (Other)	0.000	0.619	0.381
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.000	0.619	0.381
M81.46 Drug-induced osteoporosis (Lower leg)	0.000	0.619	0.381
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.000	0.619	0.381
M81.44 Drug-induced osteoporosis (Hand)	0.000	0.619	0.381
M81.43 Drug-induced osteoporosis (Forearm)	0.000	0.619	0.381
M81.42 Drug-induced osteoporosis (Upper arm)	0.000	0.619	0.381
M81.41 Drug-induced osteoporosis (Shoulder region)	0.000	0.619	0.381
S82.61 Fracture of lateral malleolus (open)	0.000	0.619	0.381
M81.08 Postmenopausal osteoporosis (Other)	0.000	0.629	0.371
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.000	0.629	0.371
M81.06 Postmenopausal osteoporosis (Lower leg)	0.000	0.629	0.371
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.000	0.629	0.371
M81.04 Postmenopausal osteoporosis (Hand)	0.000	0.629	0.371
M81.03 Postmenopausal osteoporosis (Forearm)	0.000	0.629	0.371
M81.02 Postmenopausal osteoporosis (Upper arm)	0.000	0.629	0.371
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.000	0.629	0.371
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.000	0.629	0.371
S82.71 Multiple fractures of lower leg (open)	0.000	0.629	0.370
S82.41 Fracture of fibula alone (open)	0.000	0.636	0.364
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.000	0.641	0.358
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.000	0.646	0.354
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.000	0.646	0.354
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.000	0.646	0.354
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.000	0.646	0.354
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.000	0.646	0.354
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.000	0.646	0.354
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.000	0.646	0.354
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.000	0.646	0.354
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.000	0.646	0.354
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.000	0.649	0.351
M81.18 Postoophorectomy osteoporosis (Other)	0.000	0.649	0.351
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.000	0.649	0.351
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.000	0.649	0.351
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.000	0.649	0.351
M81.14 Postoophorectomy osteoporosis (Hand)	0.000	0.649	0.351
M81.13 Postoophorectomy osteoporosis (Forearm)	0.000	0.649	0.351
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.000	0.649	0.351
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.000	0.649	0.351
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.000	0.649	0.351
M81.59 Idiopathic osteoporosis (Site unspecified)	0.000	0.649	0.351
M81.58 Idiopathic osteoporosis (Other)	0.000	0.649	0.351
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.000	0.649	0.351
M81.56 Idiopathic osteoporosis (Lower leg)	0.000	0.649	0.351
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.000	0.649	0.351
M81.54 Idiopathic osteoporosis (Hand)	0.000	0.649	0.351
M81.53 Idiopathic osteoporosis (Forearm)	0.000	0.649	0.351
M81.52 Idiopathic osteoporosis (Upper arm)	0.000	0.649	0.351
M81.51 Idiopathic osteoporosis (Shoulder region)	0.000	0.649	0.351
M81.50 Idiopathic osteoporosis (Multiple sites)	0.000	0.649	0.351
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.000	0.649	0.351
M81.68 Localized osteoporosis [Lequesne] (Other)	0.000	0.649	0.351
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.000	0.649	0.351
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.000	0.649	0.351
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.000	0.649	0.351
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.000	0.649	0.351
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.000	0.649	0.351
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.000	0.649	0.351
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.000	0.649	0.351
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.000	0.649	0.351
M81.89 Other osteoporosis (Site unspecified)	0.000	0.649	0.351
M81.88 Other osteoporosis (Other)	0.000	0.649	0.351
M81.87 Other osteoporosis (Ankle and foot)	0.000	0.649	0.351
M81.86 Other osteoporosis (Lower leg)	0.000	0.649	0.351
M81.85 Other osteoporosis (Pelvic region and thigh)	0.000	0.649	0.351
M81.84 Other osteoporosis (Hand)	0.000	0.649	0.351
M81.83 Other osteoporosis (Forearm)	0.000	0.649	0.351
M81.82 Other osteoporosis (Upper arm)	0.000	0.649	0.351
M81.81 Other osteoporosis (Shoulder region)	0.000	0.649	0.351
M81.80 Other osteoporosis (Multiple sites)	0.000	0.649	0.351
S82.31 Fracture of lower end of tibia (open)	0.000	0.658	0.342
S52.21 Fracture of shaft of ulna (open)	0.001	0.658	0.341
S82.91 Fracture of lower leg, part unspecified (open)	0.000	0.670	0.329
S82.90 Fracture of lower leg, part unspecified (closed)	0.000	0.670	0.329
S82.2 Fracture of shaft of tibia	0.000	0.695	0.305
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.698	0.302
M80-M85 Disorders of bone density and structure	0.000	0.708	0.291
M84 Disorders of continuity of bone	0.000	0.726	0.274
S52.00 Fracture of upper end of ulna (closed)	0.000	0.730	0.270
S80-S89 Injuries to the knee and lower leg	0.000	0.731	0.269
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.736	0.264
S52.20 Fracture of shaft of ulna (closed)	0.001	0.753	0.247
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.753	0.247
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.754	0.246
S89 Other and unspecified injuries of lower leg	0.000	0.775	0.225
M83 Adult osteomalacia	0.000	0.784	0.216
M84.0 Malunion of fracture	0.000	0.784	0.216
S86 Injury of muscle and tendon at lower leg level	0.000	0.786	0.214
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.795	0.205
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.800	0.200
M84.3 Stress fracture, not elsewhere classified	0.000	0.802	0.198
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.803	0.197
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.803	0.197
M84.9 Disorder of continuity of bone, unspecified	0.000	0.804	0.196
M84.2 Delayed union of fracture	0.000	0.804	0.196
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.804	0.196
S88 Traumatic amputation of lower leg	0.000	0.807	0.193
S87 Crushing injury of lower leg	0.000	0.807	0.193
S85 Injury of blood vessels at lower leg level	0.000	0.807	0.193
S84 Injury of nerves at lower leg level	0.000	0.807	0.193
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.810	0.190
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.810	0.190
S89.9 Unspecified injury of lower leg	0.000	0.811	0.189
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.816	0.184
M84.03 Malunion of fracture (Forearm)	0.000	0.818	0.182
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.823	0.177
S82.21 Fracture of shaft of tibia (open)	0.000	0.824	0.176
M84.4 Pathological fracture, not elsewhere classified	0.000	0.826	0.174
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.000	0.826	0.174
S81 Open wound of lower leg	0.000	0.827	0.173
S89.8 Other specified injuries of lower leg	0.000	0.828	0.172
M82 Osteoporosis in diseases classified elsewhere	0.001	0.829	0.171
Z47 Other orthopaedic follow-up care	0.000	0.830	0.170
M84.8 Other disorders of continuity of bone	0.000	0.831	0.169
M84.05 Malunion of fracture (Pelvic region and thigh)	0.000	0.833	0.167
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.000	0.837	0.163
M84.01 Malunion of fracture (Shoulder region)	0.000	0.838	0.162
S89.7 Multiple injuries of lower leg	0.000	0.838	0.162
S89.1 Other specified injuries of lower leg	0.000	0.838	0.162
S89.0 Multiple injuries of lower leg	0.000	0.838	0.162
M84.04 Malunion of fracture (Hand)	0.000	0.840	0.160
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.000	0.841	0.159
M83.8 Other adult osteomalacia	0.000	0.842	0.158
M83.1 Senile osteomalacia	0.000	0.842	0.158
M84.02 Malunion of fracture (Upper arm)	0.000	0.844	0.156
M83.9 Adult osteomalacia, unspecified	0.000	0.845	0.155
M83.5 Other drug-induced osteomalacia in adults	0.000	0.845	0.155
M83.4 Aluminum bone disease	0.000	0.845	0.155
M83.3 Adult osteomalacia due to malnutrition	0.000	0.845	0.155
M83.2 Adult osteomalacia due to malabsorption	0.000	0.845	0.155
M83.0 Puerperal osteomalacia	0.000	0.845	0.155
S83.7 Injury to multiple structures of knee	0.000	0.845	0.155
M84.09 Malunion of fracture (Site unspecified)	0.000	0.845	0.155
M84.00 Malunion of fracture (Multiple sites)	0.000	0.845	0.155
S86.0 Injury of Achilles tendon	0.000	0.847	0.153
S86.7 Injury of multiple muscles and tendons at lower leg level	0.000	0.847	0.153
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.000	0.847	0.153
M85 Other disorders of bone density and structure	0.000	0.853	0.147
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.855	0.145
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.000	0.856	0.144
S82.20 Fracture of shaft of tibia (closed)	0.000	0.857	0.143
S81.7 Multiple open wounds of lower leg	0.000	0.857	0.143
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.000	0.858	0.142
M84.38 Stress fracture, not elsewhere classified (Other)	0.000	0.858	0.142
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.000	0.858	0.142
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.858	0.142
M84.34 Stress fracture, not elsewhere classified (Hand)	0.000	0.858	0.142
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.000	0.858	0.142
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.000	0.858	0.142
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.000	0.858	0.142
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.000	0.858	0.142
S83.3 Tear of articular cartilage of knee, current	0.000	0.858	0.142
S83.1 Dislocation of knee	0.000	0.858	0.142
M84.29 Delayed union of fracture (Site unspecified)	0.000	0.859	0.141
M84.28 Delayed union of fracture (Other)	0.000	0.859	0.141
M84.27 Delayed union of fracture (Ankle and foot)	0.000	0.859	0.141
M84.26 Delayed union of fracture (Lower leg)	0.000	0.859	0.141
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.000	0.859	0.141
M84.24 Delayed union of fracture (Hand)	0.000	0.859	0.141
M84.23 Delayed union of fracture (Forearm)	0.000	0.859	0.141
M84.22 Delayed union of fracture (Upper arm)	0.000	0.859	0.141
M84.21 Delayed union of fracture (Shoulder region)	0.000	0.859	0.141
M84.20 Delayed union of fracture (Multiple sites)	0.000	0.859	0.141
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.000	0.859	0.141
M84.98 Disorder of continuity of bone, unspecified (Other)	0.000	0.859	0.141
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.000	0.859	0.141
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.000	0.859	0.141
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.000	0.859	0.141
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.000	0.859	0.141
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.000	0.859	0.141
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.000	0.859	0.141
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.000	0.859	0.141
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.000	0.859	0.141
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.859	0.141
M80 Osteoporosis with pathological fracture	0.000	0.859	0.141
M84.08 Malunion of fracture (Other)	0.000	0.860	0.139
S84.9 Injury of unspecified nerve at lower leg level	0.000	0.862	0.138
S84.8 Injury of other nerves at lower leg level	0.000	0.862	0.138
S84.7 Injury of multiple nerves at lower leg level	0.000	0.862	0.138
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.000	0.862	0.138
S84.1 Injury of peroneal nerve at lower leg level	0.000	0.862	0.138
S84.0 Injury of tibial nerve at lower leg level	0.000	0.862	0.138
S85.9 Injury of unspecified blood vessel at lower leg level	0.000	0.862	0.138
S85.8 Injury of other blood vessels at lower leg level	0.000	0.862	0.138
S85.7 Injury of multiple blood vessels at lower leg level	0.000	0.862	0.138
S85.5 Injury of popliteal vein	0.000	0.862	0.138
S85.4 Injury of lesser saphenous vein at lower leg level	0.000	0.862	0.138
S85.3 Injury of greater saphenous vein at lower leg level	0.000	0.862	0.138
S85.2 Injury of peroneal artery	0.000	0.862	0.138
S85.1 Injury of (anterior)(posterior) tibial artery	0.000	0.862	0.138
S85.0 Injury of popliteal artery	0.000	0.862	0.138
S87.8 Crushing injury of other and unspecified parts of lower leg	0.000	0.862	0.138
S87.0 Crushing injury of knee	0.000	0.862	0.138
S88.9 Traumatic amputation of lower leg, level unspecified	0.000	0.862	0.138
S88.1 Traumatic amputation at level between knee and ankle	0.000	0.862	0.138
S88.0 Traumatic amputation at knee level	0.000	0.862	0.138
S86.8 Injury of other muscles and tendons at lower leg level	0.000	0.864	0.136
M84.06 Malunion of fracture (Lower leg)	0.000	0.866	0.134
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.868	0.132
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.000	0.875	0.125
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.000	0.875	0.125
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.000	0.875	0.125
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.000	0.875	0.125
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.000	0.875	0.125
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.000	0.875	0.125
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.000	0.875	0.125
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.000	0.875	0.125
M82.8 Osteoporosis in other diseases classified elsewhere	0.001	0.877	0.123
M82.0 Osteoporosis in multiple myelomatosis	0.001	0.877	0.123
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.001	0.877	0.123
S83.0 Dislocation of patella	0.000	0.878	0.122
M84.89 Other disorders of continuity of bone (Site unspecified)	0.000	0.879	0.121
M84.88 Other disorders of continuity of bone (Other)	0.000	0.879	0.121
M84.86 Other disorders of continuity of bone (Lower leg)	0.000	0.879	0.121
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.000	0.879	0.121
M84.84 Other disorders of continuity of bone (Hand)	0.000	0.879	0.121
M84.82 Other disorders of continuity of bone (Upper arm)	0.000	0.879	0.121
M84.81 Other disorders of continuity of bone (Shoulder region)	0.000	0.879	0.121
M84.80 Other disorders of continuity of bone (Multiple sites)	0.000	0.879	0.121
S81.9 Open wound of lower leg, part unspecified	0.000	0.880	0.120
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.880	0.120
M83.80 Other adult osteomalacia (Multiple sites)	0.000	0.883	0.117
M83.12 Senile osteomalacia (Upper arm)	0.000	0.883	0.117
M80.8 Other osteoporosis with pathological fracture	0.000	0.884	0.116
M85.6 Other cyst of bone	0.000	0.885	0.115
S81.0 Open wound of knee	0.000	0.886	0.114
M83.89 Other adult osteomalacia (Site unspecified)	0.000	0.886	0.114
M83.88 Other adult osteomalacia (Other)	0.000	0.886	0.114
M83.87 Other adult osteomalacia (Ankle and foot)	0.000	0.886	0.114
M83.86 Other adult osteomalacia (Lower leg)	0.000	0.886	0.114
M83.85 Other adult osteomalacia (Pelvic region and thigh)	0.000	0.886	0.114
M83.84 Other adult osteomalacia (Hand)	0.000	0.886	0.114
M83.83 Other adult osteomalacia (Forearm)	0.000	0.886	0.114
M83.82 Other adult osteomalacia (Upper arm)	0.000	0.886	0.114
M83.81 Other adult osteomalacia (Shoulder region)	0.000	0.886	0.114
M83.19 Senile osteomalacia (Site unspecified)	0.000	0.886	0.114
M83.18 Senile osteomalacia (Other)	0.000	0.886	0.114
M83.17 Senile osteomalacia (Ankle and foot)	0.000	0.886	0.114
M83.16 Senile osteomalacia (Lower leg)	0.000	0.886	0.114
M83.15 Senile osteomalacia (Pelvic region and thigh)	0.000	0.886	0.114
M83.14 Senile osteomalacia (Hand)	0.000	0.886	0.114
M83.13 Senile osteomalacia (Forearm)	0.000	0.886	0.114
M83.11 Senile osteomalacia (Shoulder region)	0.000	0.886	0.114
M83.10 Senile osteomalacia (Multiple sites)	0.000	0.886	0.114
M84.83 Other disorders of continuity of bone (Forearm)	0.000	0.887	0.112
S80 Superficial injury of lower leg	0.000	0.888	0.112
M83.09 Puerperal osteomalacia (Site unspecified)	0.000	0.889	0.111
M83.08 Puerperal osteomalacia (Other)	0.000	0.889	0.111
M83.07 Puerperal osteomalacia (Ankle and foot)	0.000	0.889	0.111
M83.06 Puerperal osteomalacia (Lower leg)	0.000	0.889	0.111
M83.05 Puerperal osteomalacia (Pelvic region and thigh)	0.000	0.889	0.111
M83.04 Puerperal osteomalacia (Hand)	0.000	0.889	0.111
M83.03 Puerperal osteomalacia (Forearm)	0.000	0.889	0.111
M83.02 Puerperal osteomalacia (Upper arm)	0.000	0.889	0.111
M83.01 Puerperal osteomalacia (Shoulder region)	0.000	0.889	0.111
M83.00 Puerperal osteomalacia (Multiple sites)	0.000	0.889	0.111
M83.29 Adult osteomalacia due to malabsorption (Site unspecified)	0.000	0.889	0.111
M83.28 Adult osteomalacia due to malabsorption (Other)	0.000	0.889	0.111
M83.27 Adult osteomalacia due to malabsorption (Ankle and foot)	0.000	0.889	0.111
M83.26 Adult osteomalacia due to malabsorption (Lower leg)	0.000	0.889	0.111
M83.25 Adult osteomalacia due to malabsorption (Pelvic region and thigh)	0.000	0.889	0.111
M83.24 Adult osteomalacia due to malabsorption (Hand)	0.000	0.889	0.111
M83.23 Adult osteomalacia due to malabsorption (Forearm)	0.000	0.889	0.111
M83.22 Adult osteomalacia due to malabsorption (Upper arm)	0.000	0.889	0.111
M83.21 Adult osteomalacia due to malabsorption (Shoulder region)	0.000	0.889	0.111
M83.20 Adult osteomalacia due to malabsorption (Multiple sites)	0.000	0.889	0.111
M83.39 Adult osteomalacia due to malnutrition (Site unspecified)	0.000	0.889	0.111
M83.38 Adult osteomalacia due to malnutrition (Other)	0.000	0.889	0.111
M83.37 Adult osteomalacia due to malnutrition (Ankle and foot)	0.000	0.889	0.111
M83.36 Adult osteomalacia due to malnutrition (Lower leg)	0.000	0.889	0.111
M83.35 Adult osteomalacia due to malnutrition (Pelvic region and thigh)	0.000	0.889	0.111
M83.34 Adult osteomalacia due to malnutrition (Hand)	0.000	0.889	0.111
M83.33 Adult osteomalacia due to malnutrition (Forearm)	0.000	0.889	0.111
M83.32 Adult osteomalacia due to malnutrition (Upper arm)	0.000	0.889	0.111
M83.31 Adult osteomalacia due to malnutrition (Shoulder region)	0.000	0.889	0.111
M83.30 Adult osteomalacia due to malnutrition (Multiple sites)	0.000	0.889	0.111
M83.49 Aluminium bone disease (Site unspecified)	0.000	0.889	0.111
M83.48 Aluminium bone disease (Other)	0.000	0.889	0.111
M83.47 Aluminium bone disease (Ankle and foot)	0.000	0.889	0.111
M83.46 Aluminium bone disease (Lower leg)	0.000	0.889	0.111
M83.45 Aluminium bone disease (Pelvic region and thigh)	0.000	0.889	0.111
M83.44 Aluminium bone disease (Hand)	0.000	0.889	0.111
M83.43 Aluminium bone disease (Forearm)	0.000	0.889	0.111
M83.42 Aluminium bone disease (Upper arm)	0.000	0.889	0.111
M83.41 Aluminium bone disease (Shoulder region)	0.000	0.889	0.111
M83.40 Aluminium bone disease (Multiple sites)	0.000	0.889	0.111
M83.59 Other drug-induced osteomalacia in adults (Site unspecified)	0.000	0.889	0.111
M83.58 Other drug-induced osteomalacia in adults (Other)	0.000	0.889	0.111
M83.57 Other drug-induced osteomalacia in adults (Ankle and foot)	0.000	0.889	0.111
M83.56 Other drug-induced osteomalacia in adults (Lower leg)	0.000	0.889	0.111
M83.55 Other drug-induced osteomalacia in adults (Pelvic region and thigh)	0.000	0.889	0.111
M83.54 Other drug-induced osteomalacia in adults (Hand)	0.000	0.889	0.111
M83.53 Other drug-induced osteomalacia in adults (Forearm)	0.000	0.889	0.111
M83.52 Other drug-induced osteomalacia in adults (Upper arm)	0.000	0.889	0.111
M83.51 Other drug-induced osteomalacia in adults (Shoulder region)	0.000	0.889	0.111
M83.50 Other drug-induced osteomalacia in adults (Multiple sites)	0.000	0.889	0.111
M83.99 Adult osteomalacia, unspecified (Site unspecified)	0.000	0.889	0.111
M83.98 Adult osteomalacia, unspecified (Other)	0.000	0.889	0.111
M83.97 Adult osteomalacia, unspecified (Ankle and foot)	0.000	0.889	0.111
M83.96 Adult osteomalacia, unspecified (Lower leg)	0.000	0.889	0.111
M83.95 Adult osteomalacia, unspecified (Pelvic region and thigh)	0.000	0.889	0.111
M83.94 Adult osteomalacia, unspecified (Hand)	0.000	0.889	0.111
M83.93 Adult osteomalacia, unspecified (Forearm)	0.000	0.889	0.111
M83.92 Adult osteomalacia, unspecified (Upper arm)	0.000	0.889	0.111
M83.91 Adult osteomalacia, unspecified (Shoulder region)	0.000	0.889	0.111
M83.90 Adult osteomalacia, unspecified (Multiple sites)	0.000	0.889	0.111
S86.00 Unspecified injury of Achilles tendon	0.000	0.890	0.110
Z47.9 Orthopaedic follow-up care, unspecified	0.000	0.894	0.106
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.000	0.894	0.105
S50-S59 Injuries to the elbow and forearm	0.000	0.894	0.106
M85.5 Aneurysmal bone cyst	0.000	0.894	0.105
M85.4 Solitary bone cyst	0.000	0.894	0.105
M85.3 Osteitis condensans	0.000	0.894	0.105
M85.1 Skeletal fluorosis	0.000	0.894	0.105
M85.2 Hyperostosis of skull	0.000	0.896	0.103
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.000	0.897	0.103
M85.9 Disorder of bone density and structure, unspecified	0.000	0.898	0.102
M80.4 Drug-induced osteoporosis with pathological fracture	0.000	0.899	0.101
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.000	0.899	0.101
M80.2 Osteoporosis of disuse with pathological fracture	0.000	0.899	0.101
M80.88 Other osteoporosis with pathological fracture (Other)	0.000	0.902	0.098
M85.0 Fibrous dysplasia (monostotic)	0.000	0.906	0.094
M85.65 Other cyst of bone (Pelvic region and thigh)	0.000	0.909	0.091
S80.1 Contusion of other and unspecified parts of lower leg	0.000	0.910	0.090
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.910	0.090
M84.48 Pathological fracture, not elsewhere classified (Other)	0.000	0.911	0.089
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.001	0.911	0.089
S81.8 Open wound of other parts of lower leg	0.000	0.911	0.089
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)	0.001	0.911	0.088
M82.08 Osteoporosis in multiple myelomatosis (Other)	0.001	0.911	0.088
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)	0.001	0.911	0.088
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)	0.001	0.911	0.088
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)	0.001	0.911	0.088
M82.04 Osteoporosis in multiple myelomatosis (Hand)	0.001	0.911	0.088
M82.03 Osteoporosis in multiple myelomatosis (Forearm)	0.001	0.911	0.088
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)	0.001	0.911	0.088
M82.01 Osteoporosis in multiple myelomatosis (Shoulder region)	0.001	0.911	0.088
M82.00 Osteoporosis in multiple myelomatosis (Multiple sites)	0.001	0.911	0.088
M82.89 Osteoporosis in other diseases classified elsewhere (Site unspecified)	0.001	0.911	0.088
M82.88 Osteoporosis in other diseases classified elsewhere (Other)	0.001	0.911	0.088
M82.87 Osteoporosis in other diseases classified elsewhere (Ankle and foot)	0.001	0.911	0.088
M82.86 Osteoporosis in other diseases classified elsewhere (Lower leg)	0.001	0.911	0.088
M82.85 Osteoporosis in other diseases classified elsewhere (Pelvic region and thigh)	0.001	0.911	0.088
M82.84 Osteoporosis in other diseases classified elsewhere (Hand)	0.001	0.911	0.088
M82.83 Osteoporosis in other diseases classified elsewhere (Forearm)	0.001	0.911	0.088
M82.82 Osteoporosis in other diseases classified elsewhere (Upper arm)	0.001	0.911	0.088
M82.81 Osteoporosis in other diseases classified elsewhere (Shoulder region)	0.001	0.911	0.088
M82.80 Osteoporosis in other diseases classified elsewhere (Multiple sites)	0.001	0.911	0.088
M82.1 Osteoporosis in endocrine disorders	0.001	0.915	0.084
M85.67 Other cyst of bone (Ankle and foot)	0.000	0.915	0.085
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.000	0.917	0.083
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.000	0.917	0.083
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.000	0.917	0.083
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.917	0.083
M80.84 Other osteoporosis with pathological fracture (Hand)	0.000	0.917	0.083
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.000	0.917	0.083
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.000	0.917	0.083
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.000	0.917	0.083
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.000	0.917	0.083
M85.69 Other cyst of bone (Site unspecified)	0.000	0.917	0.083
M85.66 Other cyst of bone (Lower leg)	0.000	0.917	0.083
M85.64 Other cyst of bone (Hand)	0.000	0.917	0.083
M85.63 Other cyst of bone (Forearm)	0.000	0.917	0.083
M85.62 Other cyst of bone (Upper arm)	0.000	0.917	0.083
M85.61 Other cyst of bone (Shoulder region)	0.000	0.917	0.083
M85.60 Other cyst of bone (Multiple sites)	0.000	0.917	0.083
M85.68 Other cyst of bone (Other)	0.000	0.918	0.082
M80.0 Postmenopausal osteoporosis with pathological fracture	0.000	0.918	0.082
S80.9 Superficial injury of lower leg, unspecified	0.000	0.918	0.082
S62.60 Fracture of other finger (closed)	0.000	0.921	0.079
S59 Other and unspecified injuries of forearm	0.000	0.921	0.079
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.000	0.924	0.076
S58 Traumatic amputation of forearm	0.000	0.924	0.076
S57 Crushing injury of forearm	0.000	0.924	0.076
M85.19 Skeletal fluorosis (Site unspecified)	0.000	0.924	0.076
M85.18 Skeletal fluorosis (Other)	0.000	0.924	0.076
M85.17 Skeletal fluorosis (Ankle and foot)	0.000	0.924	0.076
M85.16 Skeletal fluorosis (Lower leg)	0.000	0.924	0.076
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.000	0.924	0.076
M85.14 Skeletal fluorosis (Hand)	0.000	0.924	0.076
M85.13 Skeletal fluorosis (Forearm)	0.000	0.924	0.076
M85.12 Skeletal fluorosis (Upper arm)	0.000	0.924	0.076
M85.11 Skeletal fluorosis (Shoulder region)	0.000	0.924	0.076
M85.10 Skeletal fluorosis (Multiple sites)	0.000	0.924	0.076
M85.39 Osteitis condensans (Site unspecified)	0.000	0.924	0.076
M85.38 Osteitis condensans (Other)	0.000	0.924	0.076
M85.37 Osteitis condensans (Ankle and foot)	0.000	0.924	0.076
M85.36 Osteitis condensans (Lower leg)	0.000	0.924	0.076
M85.35 Osteitis condensans (Pelvic region and thigh)	0.000	0.924	0.076
M85.34 Osteitis condensans (Hand)	0.000	0.924	0.076
M85.33 Osteitis condensans (Forearm)	0.000	0.924	0.076
M85.32 Osteitis condensans (Upper arm)	0.000	0.924	0.076
M85.31 Osteitis condensans (Shoulder region)	0.000	0.924	0.076
M85.30 Osteitis condensans (Multiple sites)	0.000	0.924	0.076
M85.49 Solitary bone cyst (Site unspecified)	0.000	0.924	0.076
M85.48 Solitary bone cyst (Other)	0.000	0.924	0.076
M85.47 Solitary bone cyst (Ankle and foot)	0.000	0.924	0.076
M85.46 Solitary bone cyst (Lower leg)	0.000	0.924	0.076
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.000	0.924	0.076
M85.44 Solitary bone cyst (Hand)	0.000	0.924	0.076
M85.43 Solitary bone cyst (Forearm)	0.000	0.924	0.076
M85.42 Solitary bone cyst (Upper arm)	0.000	0.924	0.076
M85.41 Solitary bone cyst (Shoulder region)	0.000	0.924	0.076
M85.40 Solitary bone cyst (Multiple sites)	0.000	0.924	0.076
M85.59 Aneurysmal bone cyst (Site unspecified)	0.000	0.924	0.076
M85.58 Aneurysmal bone cyst (Other)	0.000	0.924	0.076
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.000	0.924	0.076
M85.56 Aneurysmal bone cyst (Lower leg)	0.000	0.924	0.076
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.000	0.924	0.076
M85.54 Aneurysmal bone cyst (Hand)	0.000	0.924	0.076
M85.53 Aneurysmal bone cyst (Forearm)	0.000	0.924	0.076
M85.52 Aneurysmal bone cyst (Upper arm)	0.000	0.924	0.076
M85.51 Aneurysmal bone cyst (Shoulder region)	0.000	0.924	0.076
M85.50 Aneurysmal bone cyst (Multiple sites)	0.000	0.924	0.076
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.000	0.925	0.075
M85.29 Hyperostosis of skull-Site unspec	0.000	0.925	0.074

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations