TreeWAS – Variant ID: rs3807375

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H40.1 Primary open-angle glaucoma	0.353	0.647	0.000
H40 Glaucoma	0.156	0.844	0.000
H40.9 Glaucoma, unspecified	0.129	0.871	0.000
H40.0 Glaucoma suspect	0.122	0.878	0.000
H40.4 Glaucoma secondary to eye inflammation	0.120	0.880	0.000
H40.5 Glaucoma secondary to other eye disorders	0.115	0.885	0.000
H40.6 Glaucoma secondary to drugs	0.112	0.888	0.000
H40.3 Glaucoma secondary to eye trauma	0.104	0.896	0.000
H40.8 Other glaucoma	0.091	0.908	0.000
H40-H42 Glaucoma	0.084	0.916	0.000
H42 Glaucoma in diseases classified elsewhere	0.061	0.939	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.044	0.956	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.044	0.956	0.000
H27.0 Aphakia	0.033	0.967	0.000
Chapter VII Diseases of the eye and adnexa	0.032	0.968	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.031	0.969	0.000
H27 Other disorders of lens	0.031	0.969	0.000
H25-H28 Disorders of lens	0.031	0.969	0.000
H20 Iridocyclitis	0.029	0.971	0.000
H10-H13 Disorders of conjunctiva	0.027	0.973	0.000
H43-H45 Disorders of vitreous body and globe	0.027	0.973	0.000
H55-H59 Other disorders of eye and adnexa	0.026	0.974	0.000
H15 Disorders of sclera	0.026	0.974	0.000
H40.2 Primary angle-closure glaucoma	0.025	0.974	0.000
H20.8 Other iridocyclitis	0.025	0.975	0.000
H16 Keratitis	0.025	0.975	0.000
H20.1 Chronic iridocyclitis	0.025	0.975	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.024	0.976	0.000
H11 Other disorders of conjunctiva	0.024	0.976	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.024	0.976	0.000
H18 Other disorders of cornea	0.024	0.976	0.000
K85.9 Acute pancreatitis, unspecified	0.000	0.976	0.024
H43 Disorders of vitreous body	0.023	0.977	0.000
H27.1 Dislocation of lens	0.023	0.977	0.000
H17 Corneal scars and opacities	0.023	0.977	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.022	0.978	0.000
H26 Other cataract	0.022	0.978	0.000
H27.9 Disorder of lens, unspecified	0.022	0.978	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.022	0.978	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.022	0.978	0.000
H20.0 Acute and subacute iridocyclitis	0.022	0.978	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.022	0.978	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.021	0.979	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.021	0.979	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.021	0.979	0.000
H26.9 Cataract, unspecified	0.021	0.979	0.000
H20.9 Iridocyclitis, unspecified	0.021	0.979	0.000
H20.2 Lens-induced iridocyclitis	0.021	0.979	0.000
H11.8 Other specified disorders of conjunctiva	0.021	0.979	0.000
H18.2 Other corneal oedema	0.021	0.979	0.000
H15.8 Other disorders of sclera	0.021	0.979	0.000
I77 Other disorders of arteries and arterioles	0.000	0.980	0.020
H43.8 Other disorders of vitreous body	0.020	0.980	0.000
H16.4 Corneal neovascularisation	0.020	0.980	0.000
I77.6 Arteritis, unspecified	0.000	0.980	0.020
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.020	0.980	0.000
H44 Disorders of globe	0.020	0.980	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.020	0.980	0.000
H15.0 Scleritis	0.020	0.980	0.000
H11.9 Disorder of conjunctiva, unspecified	0.020	0.980	0.000
H16.2 Keratoconjunctivitis	0.020	0.980	0.000
H15.9 Disorder of sclera, unspecified	0.020	0.980	0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.020	0.980	0.000
H18.5 Hereditary corneal dystrophies	0.020	0.980	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.020	0.980	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.000	0.980	0.020
H43.0 Vitreous prolapse	0.019	0.981	0.000
H25.8 Other senile cataract	0.019	0.981	0.000
H18.0 Corneal pigmentations and deposits	0.019	0.981	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.019	0.981	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.019	0.981	0.000
H11.3 Conjunctival haemorrhage	0.019	0.981	0.000
I70 Atherosclerosis	0.000	0.981	0.019
H11.2 Conjunctival scars	0.019	0.981	0.000
H18.3 Changes in corneal membranes	0.019	0.981	0.000
H55 Nystagmus and other irregular eye movements	0.019	0.981	0.000
H44.0 Purulent endophthalmitis	0.019	0.981	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.019	0.981	0.000
H43.3 Other vitreous opacities	0.019	0.981	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.981	0.019
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.981	0.019
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.981	0.019
H16.8 Other keratitis	0.018	0.982	0.000
I77.1 Stricture of artery	0.000	0.982	0.018
H58.8 Visual disturbances in diseases classified elsewhere	0.018	0.982	0.000
H26.1 Traumatic cataract	0.018	0.982	0.000
H43.2 Crystalline deposits in vitreous body	0.018	0.982	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.018	0.982	0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.018	0.982	0.000
H18.9 Disorder of cornea, unspecified	0.018	0.982	0.000
H17.9 Corneal scar and opacity, unspecified	0.018	0.982	0.000
I70.0 Atherosclerosis of aorta	0.000	0.982	0.018
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.017	0.982	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.017	0.982	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.017	0.982	0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.017	0.983	0.000
H59.0 Vitreous syndrome following cataract surgery	0.017	0.983	0.000
H18.7 Other corneal deformities	0.017	0.983	0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.017	0.983	0.000
H10 Conjunctivitis	0.017	0.983	0.000
H25 Senile cataract	0.017	0.983	0.000
H15.1 Episcleritis	0.017	0.983	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.983	0.017
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.017	0.983	0.000
I73 Other peripheral vascular diseases	0.000	0.983	0.017
H26.2 Complicated cataract	0.017	0.983	0.000
H13.3 Ocular pemphigoid	0.017	0.983	0.000
H16.3 Interstitial and deep keratitis	0.017	0.983	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.983	0.017
H16.9 Keratitis, unspecified	0.017	0.983	0.000
H44.4 Hypotony of eye	0.017	0.983	0.000
I72 Other aneurysm	0.000	0.983	0.017
H17.1 Other central corneal opacity	0.016	0.983	0.000
H17.0 Adherent leukoma	0.016	0.983	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.016	0.984	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.016	0.984	0.000
H13.1 Conjunctivitis in infectious and parasitic diseases classified elsewhere	0.016	0.984	0.000
H43.9 Disorder of vitreous body, unspecified	0.016	0.984	0.000
H28.8 Other disorders of lens in diseases classified elsewhere	0.016	0.984	0.000
H28.2 Cataract in other diseases classified elsewhere	0.016	0.984	0.000
H28.1 Cataract in other endocrine, nutritional and metabolic diseases	0.016	0.984	0.000
H28.0 Diabetic cataract	0.016	0.984	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.016	0.984	0.000
H46 Optic neuritis	0.016	0.984	0.000
I72.9 Aneurysm of unspecified site	0.000	0.984	0.016
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.016	0.984	0.000
H58.1 Visual disturbances in diseases classified elsewhere	0.016	0.984	0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.016	0.984	0.000
I77.8 Other specified disorders of arteries and arterioles	0.000	0.984	0.016
H18.1 Bullous keratopathy	0.016	0.984	0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.016	0.984	0.000
H13.8 Other disorders of conjunctiva in diseases classified elsewhere	0.015	0.984	0.000
H13.2 Conjunctivitis in other diseases classified elsewhere	0.015	0.984	0.000
H13.0 Filarial infection of conjunctiva	0.015	0.984	0.000
H26.3 Drug-induced cataract	0.016	0.984	0.000
I73.9 Peripheral vascular disease, unspecified	0.000	0.984	0.016
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.015	0.984	0.000
I72.8 Aneurysm of other specified arteries	0.000	0.984	0.016
I78 Diseases of capillaries	0.000	0.985	0.015
I73.0 Raynaud's syndrome	0.000	0.985	0.015
H17.8 Other corneal scars and opacities	0.015	0.985	0.000
H18.6 Keratoconus	0.015	0.985	0.000
I77.5 Necrosis of artery	0.000	0.985	0.015
I77.4 Coeliac artery compression syndrome	0.000	0.985	0.015
I77.3 Arterial fibromuscular dysplasia	0.000	0.985	0.015
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.015	0.985	0.000
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.015	0.985	0.000
H44.6 Retained (old) intraocular foreign body, magnetic	0.015	0.985	0.000
H44.3 Other degenerative disorders of globe	0.015	0.985	0.000
I72.3 Aneurysm of iliac artery	0.000	0.985	0.015
H44.9 Disorder of globe, unspecified	0.014	0.985	0.000
H45.8 Other disorders of vitreous body and globe in diseases classified elsewhere	0.014	0.986	0.000
H45.1 Endophthalmitis in diseases classified elsewhere	0.014	0.986	0.000
H45.0 Vitreous haemorrhage in diseases classified elsewhere	0.014	0.986	0.000
H18.4 Corneal degeneration	0.014	0.986	0.000
I77.0 Arteriovenous fistula, acquired	0.000	0.986	0.014
H11.0 Pterygium	0.014	0.986	0.000
H44.8 Other disorders of globe	0.014	0.986	0.000
H21 Other disorders of iris and ciliary body	0.014	0.986	0.000
H16.0 Corneal ulcer	0.014	0.986	0.000
I70.8 Atherosclerosis of other arteries	0.000	0.986	0.014
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.986	0.014
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.986	0.013
H26.0 Infantile, juvenile and presenile cataract	0.013	0.986	0.000
H44.5 Degenerated conditions of globe	0.013	0.986	0.000
I77.2 Rupture of artery	0.000	0.986	0.013
I70.9 Generalised and unspecified atherosclerosis	0.000	0.987	0.013
I70.1 Atherosclerosis of renal artery	0.000	0.987	0.013
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.013	0.987	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.987	0.013
H47 Other disorders of optic [2nd] nerve and visual pathways	0.013	0.987	0.000
H10.8 Other conjunctivitis	0.012	0.987	0.000
H10.2 Other acute conjunctivitis	0.012	0.987	0.000
H10.1 Acute atopic conjunctivitis	0.012	0.987	0.000
H10.0 Mucopurulent conjunctivitis	0.012	0.987	0.000
H10.4 Chronic conjunctivitis	0.012	0.987	0.000
H10.5 Blepharoconjunctivitis	0.012	0.987	0.000
H25.2 Senile cataract, morgagnian type	0.012	0.987	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.988	0.012
H27.8 Other specified disorders of lens	0.012	0.988	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.988	0.012
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.988	0.012
H53-H54 Visual disturbances and blindness	0.012	0.988	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.988	0.012
H10.3 Acute conjunctivitis, unspecified	0.011	0.988	0.000
H44.2 Degenerative myopia	0.011	0.989	0.000
H48.8 Other disorders of optic nerve and visual pathways in diseases classified elsewhere	0.011	0.989	0.000
H48.1 Retrobulbar neuritis in diseases classified elsewhere	0.011	0.989	0.000
H48.0 Optic atrophy in diseases classified elsewhere	0.011	0.989	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.011	0.989	0.000
I78.8 Other diseases of capillaries	0.000	0.989	0.011
H10.9 Conjunctivitis, unspecified	0.011	0.989	0.000
H26.8 Other specified cataract	0.011	0.989	0.000
I78.9 Disease of capillaries, unspecified	0.000	0.989	0.011
H18.8 Other specified disorders of cornea	0.011	0.989	0.000
H44.1 Other endophthalmitis	0.011	0.989	0.000
H47.5 Disorders of other visual pathways	0.011	0.989	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.989	0.011
I71 Aortic aneurysm and dissection	0.000	0.989	0.011
H11.1 Conjunctival degenerations and deposits	0.010	0.990	0.000
I72.1 Aneurysm of artery of upper extremity	0.000	0.990	0.010
H21.2 Degeneration of iris and ciliary body	0.010	0.990	0.000
I72.2 Aneurysm of renal artery	0.000	0.990	0.010
H21.4 Pupillary membranes	0.010	0.990	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.010	0.990	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.990	0.010
H47.0 Disorders of optic nerve, not elsewhere classified	0.010	0.990	0.000
I73.8 Other specified peripheral vascular diseases	0.000	0.990	0.010
H21.0 Hyphaema	0.010	0.990	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.990	0.010
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.990	0.010
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.990	0.009
H47.7 Disorder of visual pathways, unspecified	0.009	0.991	0.000
H47.6 Disorders of visual cortex	0.009	0.991	0.000
H47.4 Disorders of optic chiasm	0.009	0.991	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.009	0.991	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.991	0.009
I79.1 Aortitis in diseases classified elsewhere	0.000	0.991	0.009
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.991	0.009
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.991	0.009
H57 Other disorders of eye and adnexa	0.009	0.991	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.991	0.009
H47.2 Optic atrophy	0.008	0.991	0.000
I78.1 Naevus, nonneoplastic	0.000	0.992	0.008
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.008	0.992	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.992	0.008
H26.4 After-cataract	0.008	0.992	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.992	0.008
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.992	0.008
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.992	0.008
I72.0 Aneurysm of carotid artery	0.000	0.992	0.008
H54.9 Unspecified visual impairment (binocular)	0.008	0.992	0.000
I72.4 Aneurysm of artery of lower extremity	0.000	0.992	0.008
H54 Blindness and low vision	0.008	0.992	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.992	0.007
H47.1 Papilloedema, unspecified	0.007	0.992	0.000
I71.0 Dissection of aorta [any part]	0.000	0.993	0.007
H21.5 Other adhesions and disruptions of iris and ciliary body	0.007	0.993	0.000
Z85.5 Personal history of malignant neoplasm of urinary tract	0.007	0.993	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.993	0.007
L43.9 Lichen planus, unspecified	0.000	0.993	0.007
H57.0 Anomalies of pupillary function	0.007	0.993	0.000
H57.8 Other specified disorders of eye and adnexa	0.007	0.993	0.000
K50.0 Crohn's disease of small intestine	0.007	0.993	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.993	0.007
H34.8 Other retinal vascular occlusions	0.000	0.994	0.006
H47.3 Other disorders of optic disk	0.006	0.994	0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.000	0.994	0.006
H54.4 Blindness, one eye	0.006	0.994	0.000
N43.3 Hydrocele, unspecified	0.000	0.994	0.006
H54.2 Low vision, both eyes	0.006	0.994	0.000
H54.3 Unqualified visual loss, both eyes	0.006	0.994	0.000
H25.1 Senile nuclear cataract	0.006	0.994	0.000
H51 Other disorders of binocular movement	0.005	0.994	0.000
H21.8 Other specified disorders of iris and ciliary body	0.005	0.994	0.000
H52 Disorders of refraction and accommodation	0.006	0.994	0.000
S82.8 Fractures of other parts of lower leg	0.000	0.994	0.005
H30-H36 Disorders of choroid and retina	0.005	0.995	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.995	0.005
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.995	0.005
K85 Acute pancreatitis	0.000	0.995	0.005
H54.6 Unqualified visual loss, one eye	0.005	0.995	0.000
D37.5 Rectum	0.005	0.995	0.000
H54.5 Low vision, one eye	0.005	0.995	0.000
G57.6 Lesion of plantar nerve	0.005	0.995	0.000
H52.7 Disorder of refraction, unspecified	0.005	0.995	0.000
H31 Other disorders of choroid	0.005	0.995	0.000
H30 Chorioretinal inflammation	0.005	0.995	0.000
H52.0 Hypermetropia	0.005	0.995	0.000
I49.5 Sick sinus syndrome	0.000	0.995	0.005
H52.4 Presbyopia	0.005	0.995	0.000
H31.8 Other specified disorders of choroid	0.005	0.995	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.995	0.005
I74 Arterial embolism and thrombosis	0.000	0.995	0.005
T78.4 Allergy, unspecified	0.000	0.996	0.004
H54.0 Blindness, both eyes	0.004	0.996	0.000
I21.4 Acute subendocardial myocardial infarction	0.000	0.996	0.004
T82.1 Mechanical complication of cardiac electronic device	0.000	0.996	0.004
H54.1 Blindness, one eye, low vision, other eye	0.004	0.996	0.000
H51.9 Disorder of binocular movement, unspecified	0.004	0.996	0.000
H51.8 Other specified disorders of binocular movement	0.004	0.996	0.000
H51.1 Convergence insufficiency and excess	0.004	0.996	0.000
H51.0 Palsy of conjugate gaze	0.004	0.996	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.996	0.004
J37.0 Chronic laryngitis	0.004	0.996	0.000
D37.4 Colon	0.004	0.996	0.000
H52.6 Other disorders of refraction	0.004	0.996	0.000
H52.5 Disorders of accommodation	0.004	0.996	0.000
K85.0 Idiopathic acute pancreatitis	0.000	0.996	0.004
H49 Paralytic strabismus	0.004	0.996	0.000
S82.86 Maisonneuve's fracture	0.000	0.996	0.004
H30.9 Chorioretinal inflammation, unspecified	0.004	0.996	0.000
I21 Acute myocardial infarction	0.000	0.996	0.004
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.000	0.996	0.004
H32 Chorioretinal disorders in diseases classified elsewhere	0.004	0.996	0.000
H31.0 Chorioretinal scars	0.004	0.996	0.000
H43.1 Vitreous haemorrhage	0.004	0.996	0.000
H30.2 Posterior cyclitis	0.004	0.996	0.000
B02.9 Zoster without complication	0.004	0.996	0.000
C53.9 Cervix uteri, unspecified	0.004	0.996	0.000
K85.1 Biliary acute pancreatitis	0.000	0.996	0.004
H34 Retinal vascular occlusions	0.002	0.996	0.002
N81.8 Other female genital prolapse	0.000	0.996	0.004
H51.2 Internuclear ophthalmoplegia	0.003	0.996	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.000	0.996	0.004
H49.4 Progressive external ophthalmoplegia	0.004	0.996	0.000
H31.4 Choroidal detachment	0.004	0.996	0.000
H31.2 Hereditary choroidal dystrophy	0.004	0.996	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.004	0.996	0.000
A49.0 Staphylococcal infection, unspecified	0.000	0.996	0.004
H30.8 Other chorioretinal inflammations	0.004	0.996	0.000
H30.1 Disseminated chorioretinal inflammation	0.004	0.996	0.000
H30.0 Focal chorioretinal inflammation	0.004	0.996	0.000
H31.9 Disorder of choroid, unspecified	0.003	0.996	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.996	0.004
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.996	0.004
I27.0 Primary pulmonary hypertension	0.000	0.996	0.004
H36 Retinal disorders in diseases classified elsewhere	0.004	0.996	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.003	0.996	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.004	0.996	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.996	0.003
H52.3 Anisometropia and aniseikonia	0.003	0.997	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.997	0.003
K50.9 Crohn's disease, unspecified	0.003	0.997	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.000	0.997	0.003
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.997	0.003
I74.8 Embolism and thrombosis of other arteries	0.000	0.997	0.003
K85.3 Drug-induced acute pancreatitis	0.000	0.997	0.003
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.000	0.997	0.003
H31.1 Choroidal degeneration	0.003	0.997	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.000	0.997	0.003
K50 Crohn's disease [regional enteritis]	0.003	0.997	0.000
K85.2 Alcohol-induced acute pancreatitis	0.000	0.997	0.003
C25.9 Pancreas, unspecified	0.000	0.997	0.003
H49.3 Total (external) ophthalmoplegia	0.003	0.997	0.000
H31.3 Choroidal haemorrhage and rupture	0.003	0.997	0.000
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.003	0.997	0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.997	0.003
H49.9 Paralytic strabismus, unspecified	0.003	0.997	0.000
H49.8 Other paralytic strabismus	0.003	0.997	0.000
R90 Abnormal findings on diagnostic imaging of central nervous system	0.000	0.997	0.003
H52.2 Astigmatism	0.003	0.997	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.003	0.997	0.000
H54.7 Unspecified visual loss	0.003	0.997	0.000
T82.3 Mechanical complication of other vascular grafts	0.000	0.997	0.003
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.997	0.003
L43 Lichen planus	0.000	0.997	0.003
H34.0 Transient retinal artery occlusion	0.001	0.997	0.002
H34.9 Retinal vascular occlusion, unspecified	0.001	0.997	0.002
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.997	0.003
H49.0 Third [oculomotor] nerve palsy	0.003	0.997	0.000
Z51.8 Other specified medical care	0.003	0.997	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.997	0.003
H57.1 Ocular pain	0.002	0.997	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.003	0.997	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.003	0.997	0.000
S82.81 Fractures of other parts of lower leg (open)	0.000	0.997	0.003
D68.9 Coagulation defect, unspecified	0.000	0.997	0.003
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.003	0.997	0.000
G31.8 Other specified degenerative diseases of nervous system	0.003	0.997	0.000
H34.1 Central retinal artery occlusion	0.001	0.997	0.001
K85.8 Other acute pancreatitis	0.000	0.997	0.002
Q50.5 Embryonic cyst of broad ligament	0.003	0.997	0.000
R90.0 Intracranial space-occupying lesion	0.000	0.997	0.003
M87.98 Osteonecrosis, unspecified (Other)	0.003	0.997	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.997	0.003
F25.1 Schizoaffective disorder, depressive type	0.003	0.997	0.000
H52.1 Myopia	0.003	0.997	0.000
D37.2 Small intestine	0.003	0.997	0.000
Q12.0 Congenital cataract	0.003	0.997	0.000
F25 Schizoaffective disorders	0.003	0.997	0.000
H49.2 Sixth [abducent] nerve palsy	0.002	0.997	0.000
R44.1 Visual hallucinations	0.003	0.997	0.000
F25.9 Schizoaffective disorder, unspecified	0.003	0.997	0.000
H34.2 Other retinal artery occlusions	0.001	0.997	0.002
Q53.1 Undescended testicle, unilateral	0.002	0.997	0.000
L43.8 Other lichen planus	0.000	0.997	0.002
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.002	0.997	0.000
Q50.3 Other congenital malformations of ovary	0.002	0.997	0.000
Q50.2 Congenital torsion of ovary	0.002	0.997	0.000
Q50.1 Developmental ovarian cyst	0.002	0.997	0.000
Q50.0 Congenital absence of ovary	0.002	0.997	0.000
D37.9 Digestive organ, unspecified	0.002	0.998	0.000
L43.3 Subacute (active) lichen planus	0.000	0.998	0.002
L43.2 Lichenoid drug reaction	0.000	0.998	0.002
L43.1 Bullous lichen planus	0.000	0.998	0.002
Z85.9 Personal history of malignant neoplasm, unspecified	0.002	0.998	0.000
M87.9 Osteonecrosis, unspecified	0.002	0.998	0.000
F25.0 Schizoaffective disorder, manic type	0.002	0.998	0.000
Q53 Undescended testicle	0.002	0.998	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.998	0.002
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.998	0.002
Q12 Congenital lens malformations	0.002	0.998	0.000
F02.3 Dementia in Parkinson's disease	0.002	0.998	0.000
N36.3 Prolapsed urethral mucosa	0.002	0.998	0.000
T68 Hypothermia	0.000	0.998	0.002
B02.8 Zoster with other complications	0.002	0.998	0.000
F25.2 Schizoaffective disorder, mixed type	0.002	0.998	0.000
H49.1 Fourth [trochlear] nerve palsy	0.002	0.998	0.000
Q50-Q56 Congenital malformations of genital organs	0.002	0.998	0.000
B02 Zoster [herpes zoster]	0.002	0.998	0.000
L43.0 Hypertrophic lichen planus	0.000	0.998	0.002
M79.10 Myalgia (Multiple sites)	0.002	0.998	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.002	0.998	0.000
F29 Unspecified nonorganic psychosis	0.002	0.998	0.000
L93.0 Discoid lupus erythematosus	0.002	0.998	0.000
C65 Malignant neoplasm of renal pelvis	0.002	0.998	0.000
I74.5 Embolism and thrombosis of iliac artery	0.000	0.998	0.002
K50.1 Crohn's disease of large intestine	0.002	0.998	0.000
Q61.0 Congenital single renal cyst	0.002	0.998	0.000
Q15.0 Congenital glaucoma	0.002	0.998	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.002	0.998	0.000
F25.8 Other schizoaffective disorders	0.002	0.998	0.000
H36.0 Diabetic retinopathy	0.002	0.998	0.000
I51.9 Heart disease, unspecified	0.000	0.998	0.002
Q18.1 Preauricular sinus and cyst	0.002	0.998	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.002	0.998	0.000
Q15 Other congenital malformations of eye	0.002	0.998	0.000
T78 Adverse effects, not elsewhere classified	0.000	0.998	0.002
Q55 Other congenital malformations of male genital organs	0.002	0.998	0.000
Q52 Other congenital malformations of female genitalia	0.002	0.998	0.000
I27.9 Pulmonary heart disease, unspecified	0.000	0.998	0.002
S99.9 Unspecified injury of ankle and foot	0.002	0.998	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.000	0.998	0.002
H03 Disorders of eyelid in diseases classified elsewhere	0.002	0.998	0.000
H06.2 Dysthyroid exophthalmos	0.002	0.998	0.000
I27 Other pulmonary heart diseases	0.000	0.998	0.002
C67.2 Lateral wall of bladder	0.002	0.998	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.002	0.998	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.002	0.998	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.002	0.998	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.002	0.998	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.002	0.998	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.002	0.998	0.000
Q52.1 Doubling of vagina	0.002	0.998	0.000
Q53.9 Undescended testicle, unspecified	0.002	0.998	0.000
Q53.2 Undescended testicle, bilateral	0.002	0.998	0.000
Q53.0 Ectopic testis	0.002	0.998	0.000
Q12.9 Congenital lens malformation, unspecified	0.002	0.998	0.000
Q12.8 Other congenital lens malformations	0.002	0.998	0.000
Q12.4 Spherophakia	0.002	0.998	0.000
Q12.3 Congenital aphakia	0.002	0.998	0.000
Q12.2 Coloboma of lens	0.002	0.998	0.000
Q12.1 Congenital displaced lens	0.002	0.998	0.000
Q62.5 Duplication of ureter	0.002	0.998	0.000
D37.1 Stomach	0.002	0.998	0.000
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere	0.002	0.998	0.000
Q55.6 Other congenital malformations of penis	0.002	0.998	0.000
Q63.2 Ectopic kidney	0.002	0.998	0.000
R63.8 Other symptoms and signs concerning food and fluid intake	0.002	0.998	0.000
Q18 Other congenital malformations of face and neck	0.002	0.998	0.000
B02.7 Disseminated zoster	0.002	0.998	0.000
B02.1 Zoster meningitis	0.002	0.998	0.000
B02.0 Zoster encephalitis	0.002	0.998	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.998	0.002
N60.0 Solitary cyst of breast	0.002	0.998	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.002	0.998	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.002	0.998	0.000
T78.8 Other adverse effects, not elsewhere classified	0.000	0.998	0.002
M87.96 Osteonecrosis, unspecified (Lower leg)	0.002	0.998	0.000
Y57.9 Drug or medicament, unspecified	0.000	0.998	0.002
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.002	0.998	0.000
J37 Chronic laryngitis and laryngotracheitis	0.002	0.998	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.998	0.002
Q17 Other congenital malformations of ear	0.002	0.998	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.002	0.998	0.000
K70.3 Alcoholic cirrhosis of liver	0.002	0.998	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.002	0.998	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.002	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.000	0.998	0.002
D37.3 Appendix	0.002	0.998	0.000
Q52.4 Other congenital malformations of vagina	0.002	0.998	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.000	0.998	0.002
Q13 Congenital malformations of anterior segment of eye	0.002	0.998	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.002	0.998	0.000
Q14 Congenital malformations of posterior segment of eye	0.002	0.998	0.000
B02.3 Zoster ocular disease	0.002	0.998	0.000
H06.3 Other disorders of orbit in diseases classified elsewhere	0.002	0.998	0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.002	0.998	0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.002	0.998	0.000
K50.8 Other Crohn's disease	0.002	0.998	0.000
Q15.9 Congenital malformation of eye, unspecified	0.002	0.998	0.000
Q15.8 Other specified congenital malformations of eye	0.002	0.998	0.000
Q16.9 Congenital malformation of ear causing impairment of hearing, unspecified	0.002	0.998	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.002	0.998	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.002	0.998	0.000
Q55.5 Congenital absence and aplasia of penis	0.002	0.998	0.000
Q55.3 Atresia of vas deferens	0.002	0.998	0.000
Q55.1 Hypoplasia of testis and scrotum	0.002	0.998	0.000
Q55.0 Absence and aplasia of testis	0.002	0.998	0.000
T78.9 Adverse effect, unspecified	0.000	0.998	0.002
Z93.1 Gastrostomy status	0.002	0.998	0.000
Q51.2 Other doubling of uterus	0.002	0.998	0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere	0.002	0.998	0.000
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere	0.002	0.998	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.002	0.998	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.002	0.998	0.000
Q52.7 Other congenital malformations of vulva	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations