TreeWAS – Variant ID: rs3816587

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T39.0 Salicylates	0.071	0.929	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.054	0.946	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.050	0.950	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.040	0.960	0.000
T39.4 Antirheumatics, not elsewhere classified	0.039	0.961	0.000
T39.2 Pyrazolone derivatives	0.039	0.961	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.035	0.965	0.000
T39.1 4-Aminophenol derivatives	0.035	0.965	0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.000	0.968	0.032
A41.1 Septicaemia due to other specified staphylococcus	0.000	0.974	0.026
T36-T50 Poisoning by drugs, medicaments and biological substances	0.023	0.977	0.000
C91.1 Chronic lymphocytic leukaemia	0.000	0.978	0.022
A41 Other septicaemia	0.000	0.979	0.021
E27.1 Primary adrenocortical insufficiency	0.021	0.979	0.000
E27 Other disorders of adrenal gland	0.021	0.979	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.020	0.980	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.000	0.980	0.020
A41.9 Septicaemia, unspecified	0.000	0.980	0.020
E27.2 Addisonian crisis	0.020	0.980	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.020	0.980	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.020	0.980	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.019	0.981	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.019	0.981	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.019	0.981	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.018	0.982	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.018	0.982	0.000
M31.6 Other giant cell arteritis	0.000	0.982	0.018
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.018	0.982	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.018	0.982	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.000	0.982	0.018
T41 Poisoning by anaesthetics and therapeutic gases	0.017	0.983	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.016	0.983	0.000
T36 Poisoning by systemic antibiotics	0.016	0.983	0.000
E27.9 Disorder of adrenal gland, unspecified	0.016	0.984	0.000
E27.8 Other specified disorders of adrenal gland	0.016	0.984	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.016	0.984	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.016	0.984	0.000
T40.4 Other synthetic narcotics	0.016	0.984	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.016	0.984	0.000
A41.3 Septicaemia due to Haemophilus influenzae	0.000	0.984	0.016
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.016	0.984	0.000
M87.9 Osteonecrosis, unspecified	0.015	0.985	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.015	0.985	0.000
E66.9 Obesity, unspecified	0.000	0.985	0.015
E27.5 Adrenomedullary hyperfunction	0.015	0.985	0.000
E27.0 Other adrenocortical overactivity	0.015	0.985	0.000
T48.5 Anti-common-cold drugs	0.015	0.985	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.015	0.985	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.015	0.985	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.015	0.985	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.015	0.985	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.015	0.985	0.000
T44.0 Anticholinesterase agents	0.015	0.985	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.014	0.985	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.014	0.985	0.000
T47.7 Emetics	0.014	0.985	0.000
T47.5 Digestants	0.014	0.985	0.000
T47.3 Saline and osmotic laxatives	0.014	0.985	0.000
T47.4 Other laxatives	0.014	0.985	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.014	0.986	0.000
T47.0 Histamine H(2)-receptor antagonists	0.014	0.986	0.000
T38.1 Thyroid hormones and substitutes	0.014	0.986	0.000
T47.6 Antidiarrhoeal drugs	0.014	0.986	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.014	0.986	0.000
T37.5 Antiviral drugs	0.014	0.986	0.000
T37.4 Anthelminthics	0.014	0.986	0.000
T37.3 Other antiprotozoal drugs	0.014	0.986	0.000
T37.1 Antimycobacterial drugs	0.014	0.986	0.000
T37.0 Sulphonamides	0.014	0.986	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.014	0.986	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.013	0.986	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.013	0.987	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.013	0.987	0.000
T48.4 Expectorants	0.013	0.987	0.000
T48.3 Antitussives	0.013	0.987	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.013	0.987	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.013	0.987	0.000
T48.0 Oxytocic drugs	0.013	0.987	0.000
T47.2 Stimulant laxatives	0.013	0.987	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.013	0.987	0.000
T40.5 Cocaine	0.013	0.987	0.000
T38.9 Other and unspecified hormone antagonists	0.013	0.987	0.000
T38.7 Androgens and anabolic congeners	0.013	0.987	0.000
T38.5 Other oestrogens and progestogens	0.013	0.987	0.000
T38.4 Oral contraceptives	0.013	0.987	0.000
T38.2 Antithyroid drugs	0.013	0.987	0.000
T38.0 Glucocorticoids and synthetic analogues	0.013	0.987	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.013	0.987	0.000
T40.8 Lysergide [LSD]	0.013	0.987	0.000
T40.7 Cannabis (derivatives)	0.013	0.987	0.000
T40.3 Methadone	0.013	0.987	0.000
T40.0 Opium	0.013	0.987	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.013	0.987	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.013	0.987	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.013	0.987	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.013	0.987	0.000
A41.8 Other specified septicaemia	0.000	0.987	0.013
T45.2 Vitamins, not elsewhere classified	0.013	0.987	0.000
A41.2 Septicaemia due to unspecified staphylococcus	0.000	0.987	0.012
T45.0 Antiallergic and antiemetic drugs	0.012	0.987	0.000
A41.4 Septicaemia due to anaerobes	0.000	0.988	0.012
T40.2 Other opioids	0.012	0.988	0.000
T41.5 Therapeutic gases	0.012	0.988	0.000
T41.4 Anaesthetic, unspecified	0.012	0.988	0.000
T41.3 Local anaesthetics	0.012	0.988	0.000
T41.2 Other and unspecified general anaesthetics	0.012	0.988	0.000
T41.1 Intravenous anaesthetics	0.012	0.988	0.000
T41.0 Inhaled anaesthetics	0.012	0.988	0.000
T36.9 Systemic antibiotic, unspecified	0.012	0.988	0.000
T36.8 Other systemic antibiotics	0.012	0.988	0.000
T36.7 Antifungal antibiotics, systemically used	0.012	0.988	0.000
T36.6 Rifamycins	0.012	0.988	0.000
T36.5 Aminoglycosides	0.012	0.988	0.000
T36.2 Chloramphenicol group	0.012	0.988	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.012	0.988	0.000
T36.0 Penicillins	0.012	0.988	0.000
T49.9 Topical agent, unspecified	0.012	0.988	0.000
T49.8 Other topical agents	0.012	0.988	0.000
T49.7 Dental drugs, topically applied	0.012	0.988	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.012	0.988	0.000
T49.5 Ophthalmological drugs and preparations	0.012	0.988	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.012	0.988	0.000
T49.3 Emollients, demulcents and protectants	0.012	0.988	0.000
T49.2 Local astringents and local detergents	0.012	0.988	0.000
T49.1 Antipruritics	0.012	0.988	0.000
T36.4 Tetracyclines	0.012	0.988	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.012	0.988	0.000
T36.3 Macrolides	0.012	0.988	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.012	0.988	0.000
C91 Lymphoid leukaemia	0.000	0.988	0.012
N28.1 Cyst of kidney, acquired	0.012	0.988	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.012	0.988	0.000
T45.8 Other primarily systemic and haematological agents	0.012	0.988	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.012	0.988	0.000
T45.6 Fibrinolysis-affecting drugs	0.012	0.988	0.000
T45.4 Iron and its compounds	0.012	0.988	0.000
T45.3 Enzymes, not elsewhere classified	0.012	0.988	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.012	0.988	0.000
C92.0 Acute myeloid leukaemia	0.000	0.988	0.012
T40.1 Heroin	0.011	0.989	0.000
T42.4 Benzodiazepines	0.011	0.989	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.011	0.989	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.011	0.989	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.011	0.989	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.011	0.989	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.011	0.989	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.011	0.989	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.011	0.989	0.000
T40.6 Other and unspecified narcotics	0.011	0.989	0.000
E66 Obesity	0.000	0.989	0.011
C91.0 Acute lymphoblastic leukaemia	0.000	0.990	0.010
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.010	0.990	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.010	0.990	0.000
T50.4 Drugs affecting uric acid metabolism	0.010	0.990	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.010	0.990	0.000
T42.3 Barbiturates	0.010	0.990	0.000
T42.2 Succinimides and oxazolidinediones	0.010	0.990	0.000
M87 Osteonecrosis	0.010	0.990	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.010	0.990	0.000
E66.0 Obesity due to excess calories	0.000	0.990	0.010
T50.7 Analeptics and opioid receptor antagonists	0.009	0.990	0.000
T50.5 Appetite depressants	0.009	0.990	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.009	0.990	0.000
T50.1 Loop [high-ceiling] diuretics	0.009	0.990	0.000
T50.0 Mineralocorticoids and their antagonists	0.009	0.990	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.009	0.991	0.000
T42.1 Iminostilbenes	0.009	0.991	0.000
T50.8 Diagnostic agents	0.009	0.991	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.009	0.991	0.000
C91.5 Adult T-cell leukaemia	0.000	0.991	0.009
T50.6 Antidotes and chelating agents, not elsewhere classified	0.009	0.991	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.009	0.991	0.000
H54.4 Blindness, one eye	0.000	0.991	0.009
N28 Other disorders of kidney and ureter, not elsewhere classified	0.009	0.991	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.009	0.991	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.000	0.991	0.009
C91.8 Mature B-cell leukaemia Burkitt-type	0.000	0.991	0.009
C91.7 Other lymphoid leukaemia	0.000	0.991	0.009
C91.6 Prolymphocytic leukaemia of T-cell type	0.000	0.991	0.009
C91.3 Prolymphocytic leukaemia	0.000	0.991	0.009
C91.2 Subacute lymphocytic leukaemia	0.000	0.991	0.009
M31 Other necrotising vasculopathies	0.000	0.991	0.009
E66.8 Other obesity	0.000	0.991	0.009
T45.5 Anticoagulants	0.008	0.991	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.008	0.992	0.000
H74.4 Polyp of middle ear	0.000	0.992	0.008
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.008	0.992	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.008	0.992	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.008	0.992	0.000
T46.7 Peripheral vasodilators	0.008	0.992	0.000
H53.2 Diplopia	0.000	0.992	0.008
E66.1 Drug-induced obesity	0.000	0.992	0.008
N28.0 Ischaemia and infarction of kidney	0.008	0.992	0.000
T42.0 Hydantoin derivatives	0.008	0.992	0.000
C91.9 Lymphoid leukaemia, unspecified	0.000	0.992	0.008
T46.1 Calcium-channel blockers	0.008	0.992	0.000
C91.4 Hairy-cell leukaemia	0.000	0.992	0.008
M87.0 Idiopathic aseptic necrosis of bone	0.008	0.992	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.007	0.992	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.992	0.007
T46.3 Coronary vasodilators, not elsewhere classified	0.007	0.993	0.000
M87.1 Osteonecrosis due to drugs	0.007	0.993	0.000
M87.3 Other secondary osteonecrosis	0.007	0.993	0.000
M87.8 Other osteonecrosis	0.007	0.993	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.000	0.993	0.007
M31.7 Microscopic polyangiitis	0.000	0.993	0.007
M31.4 Aortic arch syndrome [Takayasu]	0.000	0.993	0.007
M87.2 Osteonecrosis due to previous trauma	0.007	0.993	0.000
M31.8 Other specified necrotising vasculopathies	0.000	0.993	0.007
M31.1 Thrombotic microangiopathy	0.000	0.993	0.007
M31.2 Lethal midline granuloma	0.000	0.993	0.006
M31.0 Hypersensitivity angiitis	0.000	0.993	0.006
H53.1 Subjective visual disturbances	0.000	0.993	0.007
H53 Visual disturbances	0.000	0.994	0.006
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.006	0.994	0.000
M87.05 Idiopathic aseptic necrosis of bone (Pelvic region and thigh)	0.006	0.994	0.000
M87.09 Idiopathic aseptic necrosis of bone (Site unspecified)	0.006	0.994	0.000
M87.08 Idiopathic aseptic necrosis of bone (Other)	0.006	0.994	0.000
M87.07 Idiopathic aseptic necrosis of bone (Ankle and foot)	0.006	0.994	0.000
M87.06 Idiopathic aseptic necrosis of bone (Lower leg)	0.006	0.994	0.000
M87.04 Idiopathic aseptic necrosis of bone (Hand)	0.006	0.994	0.000
M87.03 Idiopathic aseptic necrosis of bone (Forearm)	0.006	0.994	0.000
M87.02 Idiopathic aseptic necrosis of bone (Upper arm)	0.006	0.994	0.000
M87.01 Idiopathic aseptic necrosis of bone (Shoulder region)	0.006	0.994	0.000
M87.00 Idiopathic aseptic necrosis of bone (Multiple sites)	0.006	0.994	0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.006	0.994	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.006	0.994	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.005	0.994	0.000
R01.0 Benign and innocent cardiac murmurs	0.006	0.994	0.000
M87.15 Osteonecrosis due to drugs (Pelvic region and thigh)	0.005	0.994	0.000
M87.19 Osteonecrosis due to drugs (Site unspecified)	0.005	0.994	0.000
M87.18 Osteonecrosis due to drugs (Other)	0.005	0.994	0.000
M87.17 Osteonecrosis due to drugs (Ankle and foot)	0.005	0.994	0.000
M87.16 Osteonecrosis due to drugs (Lower leg)	0.005	0.994	0.000
M87.14 Osteonecrosis due to drugs (Hand)	0.005	0.994	0.000
M87.13 Osteonecrosis due to drugs (Forearm)	0.005	0.994	0.000
M87.12 Osteonecrosis due to drugs (Upper arm)	0.005	0.994	0.000
M87.11 Osteonecrosis due to drugs (Shoulder region)	0.005	0.994	0.000
M87.10 Osteonecrosis due to drugs (Multiple sites)	0.005	0.994	0.000
M87.39 Other secondary osteonecrosis (Site unspecified)	0.005	0.994	0.000
M87.38 Other secondary osteonecrosis (Other)	0.005	0.994	0.000
M87.37 Other secondary osteonecrosis (Ankle and foot)	0.005	0.994	0.000
M87.36 Other secondary osteonecrosis (Lower leg)	0.005	0.994	0.000
M87.35 Other secondary osteonecrosis (Pelvic region and thigh)	0.005	0.994	0.000
M87.34 Other secondary osteonecrosis (Hand)	0.005	0.994	0.000
M87.33 Other secondary osteonecrosis (Forearm)	0.005	0.994	0.000
M87.32 Other secondary osteonecrosis (Upper arm)	0.005	0.994	0.000
M87.31 Other secondary osteonecrosis (Shoulder region)	0.005	0.994	0.000
M87.30 Other secondary osteonecrosis (Multiple sites)	0.005	0.994	0.000
M87.89 Other osteonecrosis (Site unspecified)	0.005	0.995	0.000
M87.88 Other osteonecrosis (Other)	0.005	0.995	0.000
M87.87 Other osteonecrosis (Ankle and foot)	0.005	0.995	0.000
M87.84 Other osteonecrosis (Hand)	0.005	0.995	0.000
M87.83 Other osteonecrosis (Forearm)	0.005	0.995	0.000
M87.82 Other osteonecrosis (Upper arm)	0.005	0.995	0.000
M87.81 Other osteonecrosis (Shoulder region)	0.005	0.995	0.000
M87.80 Other osteonecrosis (Multiple sites)	0.005	0.995	0.000
M86-M90 Other osteopathies	0.005	0.995	0.000
H74 Other disorders of middle ear and mastoid	0.000	0.995	0.005
M31.9 Necrotising vasculopathy, unspecified	0.000	0.995	0.005
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.005	0.995	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.005	0.995	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.005	0.995	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.005	0.995	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.005	0.995	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.005	0.995	0.000
C92 Myeloid leukaemia	0.000	0.995	0.005
H53.3 Other disorders of binocular vision	0.000	0.995	0.005
H54 Blindness and low vision	0.000	0.995	0.005
Q21.1 Atrial septal defect	0.000	0.995	0.005
M87.86 Other osteonecrosis (Lower leg)	0.005	0.995	0.000
M31.3 Wegener's granulomatosis	0.000	0.995	0.005
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.995	0.005
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.995	0.005
K59.8 Other specified functional intestinal disorders	0.000	0.995	0.005
M88 Paget's disease of bone [osteitis deformans]	0.005	0.995	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.005	0.995	0.000
H53-H54 Visual disturbances and blindness	0.000	0.995	0.005
H53.6 Night blindness	0.000	0.995	0.005
H53.5 Colour vision deficiencies	0.000	0.995	0.005
H53.4 Visual field defects	0.000	0.995	0.005
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.005	0.995	0.000
D04.7 Skin of lower limb, including hip	0.005	0.995	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.005	0.995	0.000
C92.4 Acute promyelocytic leukaemia	0.000	0.995	0.005
M90 Osteopathies in diseases classified elsewhere	0.005	0.995	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.005	0.995	0.000
T43.9 Psychotropic drug, unspecified	0.005	0.995	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.005	0.995	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.004	0.995	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.004	0.995	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.996	0.004
C49.2 Connective and soft tissue of lower limb, including hip	0.004	0.996	0.000
H54.6 Unqualified visual loss, one eye	0.000	0.996	0.004
H74.1 Adhesive middle ear disease	0.000	0.996	0.004
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.996	0.004
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.996	0.004
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.004	0.996	0.000
M88.9 Paget's disease of bone, unspecified	0.004	0.996	0.000
H53.8 Other visual disturbances	0.000	0.996	0.004
M90.7 Fracture of bone in neoplastic disease	0.004	0.996	0.000
T43.6 Psychostimulants with abuse potential	0.004	0.996	0.000
D17.7 Benign lipomatous neoplasm of other sites	0.000	0.996	0.004
T20.2 Burn of second degree of head and neck	0.004	0.996	0.000
H54.0 Blindness, both eyes	0.000	0.996	0.004
M88.0 Paget's disease of skull	0.004	0.996	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.004	0.996	0.000
M90.8 Osteopathy in other diseases classified elsewhere	0.004	0.996	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.000	0.996	0.004
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.000	0.996	0.004
C92.3 Myeloid sarcoma	0.000	0.996	0.004
C92.2 Subacute myeloid leukaemia	0.000	0.996	0.004
H54.3 Unqualified visual loss, both eyes	0.000	0.996	0.004
T43.2 Other and unspecified antidepressants	0.004	0.996	0.000
H53.0 Amblyopia ex anopsia	0.000	0.996	0.004
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.004	0.996	0.000
H54.1 Blindness, one eye, low vision, other eye	0.000	0.996	0.004
C92.5 Acute myelomonocytic leukaemia	0.000	0.996	0.004
H54.2 Low vision, both eyes	0.000	0.996	0.004
M88.8 Paget's disease of other bones	0.004	0.996	0.000
S01.1 Open wound of eyelid and periocular area	0.004	0.996	0.000
M89 Other disorders of bone	0.004	0.996	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.004	0.996	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.004	0.996	0.000
M90.5 Osteonecrosis in other diseases classified elsewhere	0.004	0.996	0.000
M90.4 Osteonecrosis due to heamoglobinopathy	0.004	0.996	0.000
M90.3 Osteonecrosis in caisson disease	0.004	0.996	0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere	0.004	0.996	0.000
M90.0 Tuberculosis of bone	0.004	0.996	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.004	0.996	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.004	0.996	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.003	0.996	0.000
C92.7 Other myeloid leukaemia	0.000	0.996	0.003
T20 Burn and corrosion of head and neck	0.004	0.996	0.000
M86 Osteomyelitis	0.004	0.996	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.003	0.996	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.000	0.996	0.004
M88.00 Paget's disease of skull-Mult sites	0.003	0.996	0.000
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.003	0.996	0.000
M90.6 Osteitis deformans in neoplastic disease	0.003	0.996	0.000
M90.80 Osteopathy in other diseases classified elsewhere (Multiple sites)	0.003	0.997	0.000
E20-E35 Disorders of other endocrine glands	0.003	0.997	0.000
C92.9 Myeloid leukaemia, unspecified	0.000	0.997	0.003
M90.1 Periostitis in other infectious diseases classified elsewhere	0.003	0.997	0.000
T20.0 Burn of unspecified degree of head and neck	0.003	0.997	0.000
E23 Hypofunction and other disorders of pituitary gland	0.003	0.997	0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.003	0.997	0.000
M88.98 Paget's disease of bone, unspecified (Other)	0.003	0.997	0.000
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.003	0.997	0.000
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.003	0.997	0.000
M88.94 Paget's disease of bone, unspecified (Hand)	0.003	0.997	0.000
M88.93 Paget's disease of bone, unspecified (Forearm)	0.003	0.997	0.000
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.003	0.997	0.000
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.003	0.997	0.000
M90.84 Osteopathy in other diseases classified elsewhere (Hand)	0.003	0.997	0.000
M89.8 Other specified disorders of bone	0.003	0.997	0.000
Q89.2 Congenital malformations of other endocrine glands	0.000	0.997	0.003
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.003	0.997	0.000
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.003	0.997	0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.003	0.997	0.000
M90.74 Fracture of bone in neoplastic disease (Hand)	0.003	0.997	0.000
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.003	0.997	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.000	0.997	0.003
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.000	0.997	0.003
H54.5 Low vision, one eye	0.000	0.997	0.003
M89.3 Hypertrophy of bone	0.003	0.997	0.000
M88.09 Paget's disease of skull-Site unspec	0.003	0.997	0.000
M88.08 Paget's disease of skull-Other	0.003	0.997	0.000
M88.07 Paget's disease of skull-Ankle/Foot	0.003	0.997	0.000
M88.06 Paget's disease of skull-Lower Leg	0.003	0.997	0.000
M88.05 Paget's disease of skull-Pelvic/Thigh	0.003	0.997	0.000
M88.04 Paget's disease of skull-Hand	0.003	0.997	0.000
M88.03 Paget's disease of skull-Forearm	0.003	0.997	0.000
M88.02 Paget's disease of skull-Upper arm	0.003	0.997	0.000
M88.01 Paget's disease of skull-Shldr region	0.003	0.997	0.000
M90.89 Osteopathy in other diseases classified elsewhere (Site unspecified)	0.003	0.997	0.000
M90.88 Osteopathy in other diseases classified elsewhere (Other)	0.003	0.997	0.000
M90.87 Osteopathy in other diseases classified elsewhere (Ankle and foot)	0.003	0.997	0.000
M90.86 Osteopathy in other diseases classified elsewhere (Lower leg)	0.003	0.997	0.000
M90.85 Osteopathy in other diseases classified elsewhere (Pelvic region and thigh)	0.003	0.997	0.000
M90.83 Osteopathy in other diseases classified elsewhere (Forearm)	0.003	0.997	0.000
M90.82 Osteopathy in other diseases classified elsewhere (Upper arm)	0.003	0.997	0.000
M90.81 Osteopathy in other diseases classified elsewhere (Shoulder region)	0.003	0.997	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.003	0.997	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
E23.2 Diabetes insipidus	0.003	0.997	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.003	0.997	0.000
E23.7 Disorder of pituitary gland, unspecified	0.003	0.997	0.000
H54.9 Unspecified visual impairment (binocular)	0.000	0.997	0.003
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.000	0.997	0.003
C81 Hodgkin's disease	0.000	0.997	0.003
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.000	0.997	0.003
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.003	0.997	0.000
M88.85 Paget's disease of other bones (Pelvic region and thigh)	0.003	0.997	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.003	0.997	0.000
Z75.3 Unavailability and inaccessibility of health-care facilities	0.000	0.997	0.003
M88.89 Paget's disease of other bones (Site unspecified)	0.003	0.997	0.000
M88.88 Paget's disease of other bones (Other)	0.003	0.997	0.000
M88.87 Paget's disease of other bones (Ankle and foot)	0.003	0.997	0.000
M88.86 Paget's disease of other bones (Lower leg)	0.003	0.997	0.000
M88.84 Paget's disease of other bones (Hand)	0.003	0.997	0.000
M88.83 Paget's disease of other bones (Forearm)	0.003	0.997	0.000
M88.82 Paget's disease of other bones (Upper arm)	0.003	0.997	0.000
M88.81 Paget's disease of other bones (Shoulder region)	0.003	0.997	0.000
M88.80 Paget's disease of other bones (Multiple sites)	0.003	0.997	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.003	0.997	0.000
M89.0 Algoneurodystrophy	0.003	0.997	0.000
E20 Hypoparathyroidism	0.003	0.997	0.000
M89.6 Osteopathy after poliomyelitis	0.003	0.997	0.000
M89.2 Other disorders of bone development and growth	0.003	0.997	0.000
M89.1 Epiphyseal arrest	0.003	0.997	0.000
E31 Polyglandular dysfunction	0.003	0.997	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.003	0.997	0.000
C81.0 Lymphocytic predominance	0.000	0.997	0.003
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.003	0.997	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.003	0.997	0.000
M90.09 Tuberculosis of bone (Site unspecified)	0.003	0.997	0.000
M90.08 Tuberculosis of bone (Other)	0.003	0.997	0.000
M90.07 Tuberculosis of bone (Ankle and foot)	0.003	0.997	0.000
M90.06 Tuberculosis of bone (Lower leg)	0.003	0.997	0.000
M90.05 Tuberculosis of bone (Pelvic region and thigh)	0.003	0.997	0.000
M90.04 Tuberculosis of bone (Hand)	0.003	0.997	0.000
M90.03 Tuberculosis of bone (Forearm)	0.003	0.997	0.000
M90.02 Tuberculosis of bone (Upper arm)	0.003	0.997	0.000
M90.01 Tuberculosis of bone (Shoulder region)	0.003	0.997	0.000
M90.00 Tuberculosis of bone (Multiple sites)	0.003	0.997	0.000
M90.29 Osteopathy in other infectious diseases classified elsewhere (Site unspecified)	0.003	0.997	0.000
M90.28 Osteopathy in other infectious diseases classified elsewhere (Other)	0.003	0.997	0.000
M90.27 Osteopathy in other infectious diseases classified elsewhere (Ankle and foot)	0.003	0.997	0.000
M90.26 Osteopathy in other infectious diseases classified elsewhere (Lower leg)	0.003	0.997	0.000
M90.25 Osteopathy in other infectious diseases classified elsewhere (Pelvic region and thigh)	0.003	0.997	0.000
M90.24 Osteopathy in other infectious diseases classified elsewhere (Hand)	0.003	0.997	0.000
M90.23 Osteopathy in other infectious diseases classified elsewhere (Forearm)	0.003	0.997	0.000
M90.22 Osteopathy in other infectious diseases classified elsewhere (Upper arm)	0.003	0.997	0.000
M90.21 Osteopathy in other infectious diseases classified elsewhere (Shoulder region)	0.003	0.997	0.000
M90.20 Osteopathy in other infectious diseases classified elsewhere (Multiple sites)	0.003	0.997	0.000
M90.39 Osteonecrosis in caisson disease (Site unspecified)	0.003	0.997	0.000
M90.38 Osteonecrosis in caisson disease (Other)	0.003	0.997	0.000
M90.37 Osteonecrosis in caisson disease (Ankle and foot)	0.003	0.997	0.000
M90.36 Osteonecrosis in caisson disease (Lower leg)	0.003	0.997	0.000
M90.35 Osteonecrosis in caisson disease (Pelvic region and thigh)	0.003	0.997	0.000
M90.34 Osteonecrosis in caisson disease (Hand)	0.003	0.997	0.000
M90.33 Osteonecrosis in caisson disease (Forearm)	0.003	0.997	0.000
M90.32 Osteonecrosis in caisson disease (Upper arm)	0.003	0.997	0.000
M90.31 Osteonecrosis in caisson disease (Shoulder region)	0.003	0.997	0.000
M90.30 Osteonecrosis in caisson disease (Multiple sites)	0.003	0.997	0.000
M90.49 Osteonecrosis due to haemoglobinopathy (Site unspecified)	0.003	0.997	0.000
M90.48 Osteonecrosis due to haemoglobinopathy (Other)	0.003	0.997	0.000
M90.47 Osteonecrosis due to haemoglobinopathy (Ankle and foot)	0.003	0.997	0.000
M90.46 Osteonecrosis due to haemoglobinopathy (Lower leg)	0.003	0.997	0.000
M90.45 Osteonecrosis due to haemoglobinopathy (Pelvic region and thigh)	0.003	0.997	0.000
M90.44 Osteonecrosis due to haemoglobinopathy (Hand)	0.003	0.997	0.000
M90.43 Osteonecrosis due to haemoglobinopathy (Forearm)	0.003	0.997	0.000
M90.42 Osteonecrosis due to haemoglobinopathy (Upper arm)	0.003	0.997	0.000
M90.41 Osteonecrosis due to haemoglobinopathy (Shoulder region)	0.003	0.997	0.000
M90.40 Osteonecrosis due to haemoglobinopathy (Multiple sites)	0.003	0.997	0.000
M90.59 Osteonecrosis in other diseases classified elsewhere (Site unspecified)	0.003	0.997	0.000
M90.58 Osteonecrosis in other diseases classified elsewhere (Other)	0.003	0.997	0.000
M90.57 Osteonecrosis in other diseases classified elsewhere (Ankle and foot)	0.003	0.997	0.000
M90.56 Osteonecrosis in other diseases classified elsewhere (Lower leg)	0.003	0.997	0.000
M90.55 Osteonecrosis in other diseases classified elsewhere (Pelvic region and thigh)	0.003	0.997	0.000
M90.54 Osteonecrosis in other diseases classified elsewhere (Hand)	0.003	0.997	0.000
M90.53 Osteonecrosis in other diseases classified elsewhere (Forearm)	0.003	0.997	0.000
M90.52 Osteonecrosis in other diseases classified elsewhere (Upper arm)	0.003	0.997	0.000
M90.51 Osteonecrosis in other diseases classified elsewhere (Shoulder region)	0.003	0.997	0.000
M90.50 Osteonecrosis in other diseases classified elsewhere (Multiple sites)	0.003	0.997	0.000
H74.0 Tympanosclerosis	0.000	0.997	0.003
D17 Benign lipomatous neoplasm	0.000	0.997	0.003
O24 Diabetes mellitus in pregnancy	0.000	0.997	0.003
T21 Burn and corrosion of trunk	0.003	0.997	0.000
M89.88 Other specified disorders of bone (Other)	0.003	0.997	0.000
E26 Hyperaldosteronism	0.003	0.997	0.000
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
T20.7 Corrosion of third degree of head and neck	0.003	0.997	0.000
T20.6 Corrosion of second degree of head and neck	0.003	0.997	0.000
T20.5 Corrosion of first degree of head and neck	0.003	0.997	0.000
T20.4 Corrosion of unspecified degree of head and neck	0.003	0.997	0.000
M86.5 Other chronic haematogenous osteomyelitis	0.003	0.997	0.000
M86.3 Chronic multifocal osteomyelitis	0.003	0.997	0.000
M86.2 Subacute osteomyelitis	0.003	0.997	0.000
M86.0 Acute haematogenous osteomyelitis	0.003	0.997	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.003	0.997	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.003	0.997	0.000
M86.6 Other chronic osteomyelitis	0.003	0.997	0.000
E65-E68 Obesity and other hyperalimentation	0.000	0.997	0.003
N25-N29 Other disorders of kidney and ureter	0.003	0.997	0.000
M90.69 Osteitis deformans in neoplastic disease (Site unspecified)	0.003	0.997	0.000
M90.68 Osteitis deformans in neoplastic disease (Other)	0.003	0.997	0.000
M90.67 Osteitis deformans in neoplastic disease (Ankle and foot)	0.003	0.997	0.000
M90.66 Osteitis deformans in neoplastic disease (Lower leg)	0.003	0.997	0.000
M90.65 Osteitis deformans in neoplastic disease (Pelvic region and thigh)	0.003	0.997	0.000
M90.64 Osteitis deformans in neoplastic disease (Hand)	0.003	0.997	0.000
M90.63 Osteitis deformans in neoplastic disease (Forearm)	0.003	0.997	0.000
M90.62 Osteitis deformans in neoplastic disease (Upper arm)	0.003	0.997	0.000
M90.60 Osteitis deformans in neoplastic disease (Multiple sites)	0.003	0.997	0.000
T20.3 Burn of third degree of head and neck	0.003	0.997	0.000
T20.1 Burn of first degree of head and neck	0.003	0.997	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.003	0.997	0.000
E32 Diseases of thymus	0.003	0.997	0.000
E30 Disorders of puberty, not elsewhere classified	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations