TreeWAS – Variant ID: rs3829849

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M16.9 Coxarthrosis, unspecified	0.000	0.005	0.995
M16.1 Other primary coxarthrosis	0.000	0.006	0.994
M16 Coxarthrosis [arthrosis of hip]	0.000	0.008	0.992
H40.9 Glaucoma, unspecified	0.000	0.138	0.862
H40.1 Primary open-angle glaucoma	0.000	0.157	0.843
H40 Glaucoma	0.000	0.160	0.840
M16.0 Primary coxarthrosis, bilateral	0.000	0.167	0.833
M16.5 Other posttraumatic coxarthrosis	0.000	0.230	0.770
M16.4 Posttraumatic coxarthrosis, bilateral	0.000	0.289	0.711
M16.7 Other secondary coxarthrosis	0.000	0.308	0.692
K22.7 Barrett's oesophagus	0.644	0.356	0.000
H40.3 Glaucoma secondary to eye trauma	0.000	0.388	0.611
H40.6 Glaucoma secondary to drugs	0.000	0.397	0.603
H40.4 Glaucoma secondary to eye inflammation	0.000	0.402	0.598
H40.0 Glaucoma suspect	0.000	0.413	0.587
M16.6 Other secondary coxarthrosis, bilateral	0.000	0.414	0.586
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.000	0.466	0.534
H40.8 Other glaucoma	0.000	0.485	0.515
H40.5 Glaucoma secondary to other eye disorders	0.000	0.489	0.511
K22 Other diseases of oesophagus	0.473	0.527	0.000
K22.0 Achalasia of cardia	0.465	0.535	0.000
K22.8 Other specified diseases of oesophagus	0.455	0.545	0.000
K22.4 Dyskinesia of oesophagus	0.378	0.622	0.000
H40-H42 Glaucoma	0.000	0.649	0.351
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.329	0.671	0.000
H40.2 Primary angle-closure glaucoma	0.000	0.678	0.322
K22.3 Perforation of oesophagus	0.320	0.680	0.000
M16.3 Other dysplastic coxarthrosis	0.001	0.740	0.258
H42 Glaucoma in diseases classified elsewhere	0.000	0.748	0.252
K22.1 Ulcer of oesophagus	0.209	0.791	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.000	0.819	0.181
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.000	0.819	0.181
K22.5 Diverticulum of oesophagus, acquired	0.154	0.845	0.000
K22.9 Disease of oesophagus, unspecified	0.131	0.869	0.000
K22.2 Oesophageal obstruction	0.120	0.880	0.000
K76.8 Other specified diseases of liver	0.000	0.961	0.039
K76 Other diseases of liver	0.000	0.961	0.039
K76.6 Portal hypertension	0.000	0.963	0.037
K76.9 Liver disease, unspecified	0.000	0.966	0.034
K75 Other inflammatory liver diseases	0.000	0.966	0.034
K76.1 Chronic passive congestion of liver	0.000	0.966	0.034
K70-K77 Diseases of liver	0.000	0.967	0.033
K75.9 Inflammatory liver disease, unspecified	0.000	0.967	0.033
K75.4 Autoimmune hepatitis	0.000	0.969	0.031
K73 Chronic hepatitis, not elsewhere classified	0.000	0.970	0.030
K76.5 Hepatic veno-occlusive disease	0.000	0.972	0.028
K76.4 Peliosis hepatis	0.000	0.972	0.028
K76.3 Infarction of liver	0.000	0.972	0.028
K76.2 Central haemorrhagic necrosis of liver	0.000	0.972	0.028
K76.7 Hepatorenal syndrome	0.000	0.972	0.028
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.972	0.028
K75.8 Other specified inflammatory liver diseases	0.000	0.972	0.028
K73.9 Chronic hepatitis, unspecified	0.000	0.975	0.025
K71 Toxic liver disease	0.000	0.975	0.025
K75.2 Nonspecific reactive hepatitis	0.000	0.975	0.025
K75.1 Phlebitis of portal vein	0.000	0.975	0.025
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.975	0.024
K77 Liver disorders in diseases classified elsewhere	0.000	0.976	0.024
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.977	0.023
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.023	0.977	0.000
M15-M19 Arthrosis	0.000	0.977	0.022
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.978	0.022
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.978	0.022
K72 Hepatic failure, not elsewhere classified	0.000	0.979	0.021
K27 Peptic ulcer, site unspecified	0.020	0.980	0.000
K71.0 Toxic liver disease with cholestasis	0.000	0.980	0.020
M54.96 Dorsalgia, unspecified (Lumbar region)	0.000	0.980	0.020
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.981	0.019
K71.9 Toxic liver disease, unspecified	0.000	0.982	0.018
K71.8 Toxic liver disease with other disorders of liver	0.000	0.982	0.018
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.982	0.018
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.982	0.018
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.982	0.018
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.982	0.018
K71.2 Toxic liver disease with acute hepatitis	0.000	0.982	0.018
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.982	0.017
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.983	0.017
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.983	0.017
D35.1 Parathyroid gland	0.017	0.983	0.000
K27.7 Chronic without haemorrhage or perforation	0.017	0.983	0.000
K27.3 Acute without haemorrhage or perforation	0.017	0.983	0.000
K72.0 Acute and subacute hepatic failure	0.000	0.984	0.016
K72.1 Chronic hepatic failure	0.000	0.985	0.015
K27.6 Chronic or unspecified with both haemorrhage and perforation	0.015	0.985	0.000
K27.5 Chronic or unspecified with perforation	0.015	0.985	0.000
K27.4 Chronic or unspecified with haemorrhage	0.015	0.985	0.000
K27.2 Acute with both haemorrhage and perforation	0.015	0.985	0.000
K27.1 Acute with perforation	0.015	0.985	0.000
K27.0 Acute with haemorrhage	0.015	0.985	0.000
K75.0 Abscess of liver	0.000	0.985	0.015
K74 Fibrosis and cirrhosis of liver	0.000	0.985	0.015
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.014	0.986	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.986	0.014
K20-K31 Diseases of oesophagus, stomach and duodenum	0.014	0.986	0.000
K70 Alcoholic liver disease	0.000	0.987	0.013
D70 Agranulocytosis	0.013	0.987	0.000
E53.8 Deficiency of other specified B group vitamins	0.000	0.987	0.013
K72.9 Hepatic failure, unspecified	0.000	0.988	0.012
M15 Polyarthrosis	0.000	0.988	0.012
K70.4 Alcoholic hepatic failure	0.000	0.989	0.011
K23 Disorders of oesophagus in diseases classified elsewhere	0.011	0.989	0.000
R94.3 Abnormal results of cardiovascular function studies	0.011	0.989	0.000
K74.0 Hepatic fibrosis	0.000	0.989	0.011
K21.0 Gastro-oesophageal reflux disease with oesophagitis	0.011	0.989	0.000
K21 Gastro-oesophageal reflux disease	0.011	0.989	0.000
K74.4 Secondary biliary cirrhosis	0.000	0.989	0.011
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.989	0.011
M18 Arthrosis of first carpometacarpal joint	0.000	0.990	0.010
K74.1 Hepatic sclerosis	0.000	0.990	0.010
A49.8 Other bacterial infections of unspecified site	0.010	0.990	0.000
K70.0 Alcoholic fatty liver	0.000	0.990	0.010
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.000	0.990	0.010
K28 Gastrojejunal ulcer	0.010	0.990	0.000
K23.8 Disorders of oesophagus in other diseases classified elsewhere	0.009	0.990	0.000
M15.8 Other polyarthrosis	0.000	0.991	0.009
K74.5 Biliary cirrhosis, unspecified	0.000	0.991	0.009
K70.1 Alcoholic hepatitis	0.000	0.991	0.009
M15.4 Erosive (osteo)arthrosis	0.000	0.991	0.009
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.991	0.009
M15.0 Primary generalised (osteo)arthrosis	0.000	0.991	0.008
M15.3 Secondary multiple arthrosis	0.000	0.992	0.008
M15.2 Bouchard's nodes (with arthropathy)	0.000	0.992	0.008
K23.1 Megaoesophagus in Chagas' disease	0.008	0.992	0.000
K23.0 Tuberculous oesophagitis	0.008	0.992	0.000
K74.3 Primary biliary cirrhosis	0.000	0.992	0.008
G57.8 Other mononeuropathies of lower limb	0.008	0.992	0.000
K74.6 Other and unspecified cirrhosis of liver	0.000	0.992	0.008
M18.1 Other primary arthrosis of first carpometacarpal joint	0.000	0.992	0.008
M15.9 Polyarthrosis, unspecified	0.000	0.992	0.008
K70.3 Alcoholic cirrhosis of liver	0.000	0.992	0.008
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.000	0.992	0.008
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.000	0.992	0.008
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.000	0.992	0.008
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.000	0.992	0.008
N62 Hypertrophy of breast	0.008	0.992	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.000	0.992	0.008
C18.6 Descending colon	0.000	0.993	0.007
K28.7 Chronic without haemorrhage or perforation	0.007	0.993	0.000
K28.6 Chronic or unspecified with both haemorrhage and perforation	0.007	0.993	0.000
K28.5 Chronic or unspecified with perforation	0.007	0.993	0.000
K28.4 Chronic or unspecified with haemorrhage	0.007	0.993	0.000
K28.3 Acute without haemorrhage or perforation	0.007	0.993	0.000
K28.2 Acute with both haemorrhage and perforation	0.007	0.993	0.000
K28.1 Acute with perforation	0.007	0.993	0.000
K28.0 Acute with haemorrhage	0.007	0.993	0.000
M15.1 Heberden's nodes (with arthropathy)	0.000	0.993	0.007
K28.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.007	0.993	0.000
N85.1 Endometrial adenomatous hyperplasia	0.007	0.993	0.000
S61.1 Open wound of finger(s) with damage to nail	0.007	0.993	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.000	0.993	0.007
D76.3 Other histiocytosis syndromes	0.007	0.993	0.000
G57.6 Lesion of plantar nerve	0.007	0.993	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.007	0.993	0.000
M15.00 Primary generalized (osteo)arthrosis, Multiple sites	0.000	0.994	0.006
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.006	0.994	0.000
M54.9 Dorsalgia, unspecified	0.000	0.994	0.006
R10.0 Acute abdomen	0.006	0.994	0.000
G57 Mononeuropathies of lower limb	0.006	0.994	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.006	0.994	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.000	0.994	0.006
D35 Benign neoplasm of other and unspecified endocrine glands	0.006	0.994	0.000
N63 Unspecified lump in breast	0.006	0.994	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.006	0.994	0.000
G57.9 Mononeuropathy of lower limb, unspecified	0.006	0.994	0.000
S61 Open wound of wrist and hand	0.005	0.995	0.000
M54.92 Dorsalgia, unspecified (Cervical region)	0.000	0.995	0.005
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.995	0.005
M15.99 Polyosteoarthritis, unspecified	0.000	0.995	0.005
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.000	0.995	0.005
D35.2 Pituitary gland	0.005	0.995	0.000
Z97.5 Presence of (intra-uterine) contraceptive device	0.005	0.995	0.000
G57.0 Lesion of sciatic nerve	0.005	0.995	0.000
G40 Epilepsy	0.000	0.995	0.005
K61.3 Ischiorectal abscess	0.000	0.995	0.005
D76.2 Haemophagocytic syndrome, infection-associated	0.005	0.995	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.005	0.995	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.005	0.995	0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.000	0.995	0.005
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.000	0.995	0.005
I05.9 Mitral valve disease, unspecified	0.005	0.995	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.995	0.005
G57.4 Lesion of medial popliteal nerve	0.005	0.995	0.000
G57.2 Lesion of femoral nerve	0.005	0.995	0.000
D74 Methaemoglobinaemia	0.005	0.995	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.005	0.995	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.005	0.995	0.000
D72 Other disorders of white blood cells	0.005	0.995	0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.000	0.995	0.004
M19 Other arthrosis	0.000	0.995	0.005
Y51 Drugs primarily affecting the autonomic nervous system	0.005	0.995	0.000
S61.8 Open wound of other parts of wrist and hand	0.005	0.995	0.000
D35.9 Endocrine gland, unspecified	0.004	0.995	0.000
D35.8 Pluriglandular involvement	0.004	0.995	0.000
D35.7 Other specified endocrine glands	0.004	0.995	0.000
D35.6 Aortic body and other paraganglia	0.004	0.995	0.000
D35.5 Carotid body	0.004	0.995	0.000
D35.4 Pineal gland	0.004	0.995	0.000
D35.3 Craniopharyngeal duct	0.004	0.995	0.000
T82.3 Mechanical complication of other vascular grafts	0.000	0.996	0.004
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.004	0.996	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.000	0.996	0.004
G57.3 Lesion of lateral popliteal nerve	0.004	0.996	0.000
G40.8 Other epilepsy	0.000	0.996	0.004
G57.5 Tarsal tunnel syndrome	0.004	0.996	0.000
S61.7 Multiple open wounds of wrist and hand	0.004	0.996	0.000
D72.1 Eosinophilia	0.004	0.996	0.000
M17.0 Primary gonarthrosis, bilateral	0.004	0.996	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.004	0.996	0.000
E53 Deficiency of other B group vitamins	0.000	0.996	0.004
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.000	0.996	0.004
M17.5 Other secondary gonarthrosis	0.004	0.996	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.000	0.996	0.004
G40.4 Other generalised epilepsy and epileptic syndromes	0.000	0.996	0.004
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.000	0.996	0.004
M19.2 Other secondary arthrosis	0.000	0.996	0.004
R13 Dysphagia	0.004	0.996	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.000	0.996	0.004
D75.8 Other specified diseases of blood and blood-forming organs	0.004	0.996	0.000
Z48.9 Surgical follow-up care, unspecified	0.000	0.996	0.004
A49 Bacterial infection of unspecified site	0.004	0.996	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.000	0.996	0.004
D75 Other diseases of blood and blood-forming organs	0.004	0.996	0.000
D74.9 Methaemoglobinaemia, unspecified	0.003	0.996	0.000
D74.8 Other methaemoglobinaemias	0.003	0.996	0.000
D74.0 Congenital methaemoglobinaemia	0.003	0.996	0.000
D72.9 Disorder of white blood cells, unspecified	0.003	0.996	0.000
D72.0 Genetic anomalies of leukocytes	0.003	0.996	0.000
Z97.8 Presence of other specified devices	0.004	0.996	0.000
R52.1 Chronic intractable pain	0.004	0.996	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.996	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.996	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.996	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.996	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.003	0.996	0.000
Y51.0 Anticholinesterase agents	0.003	0.996	0.000
Y54.3 Benzothiadiazine derivatives	0.003	0.997	0.000
D62 Acute posthaemorrhagic anaemia	0.000	0.997	0.003
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.003	0.997	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.003	0.997	0.000
G57.1 Meralgia paraesthetica	0.003	0.997	0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.003	0.997	0.000
R93 Abnormal findings on diagnostic imaging of other body structures	0.000	0.997	0.003
G40.5 Special epileptic syndromes	0.000	0.997	0.003
M19.8 Other specified arthrosis	0.000	0.997	0.003
M19.21 Other secondary arthrosis (Shoulder region)	0.000	0.997	0.003
S46.0 Injury of tendon of the rotator cuff of shoulder	0.000	0.997	0.003
M17 Gonarthrosis [arthrosis of knee]	0.003	0.997	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.000	0.997	0.003
S60.9 Superficial injury of wrist and hand, unspecified	0.000	0.997	0.003
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances	0.000	0.997	0.003
S46 Injury of muscle and tendon at shoulder and upper arm level	0.000	0.997	0.003
Z97 Presence of other devices	0.003	0.997	0.000
E53.1 Pyridoxine deficiency	0.000	0.997	0.003
E53.0 Riboflavin deficiency	0.000	0.997	0.003
S46.1 Injury of muscle and tendon of long head of biceps	0.000	0.997	0.003
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.000	0.997	0.003
A49.2 Haemophilus influenzae infection, unspecified	0.003	0.997	0.000
M19.29 Other secondary arthrosis (Site unspecified)	0.000	0.997	0.003
M19.28 Other secondary arthrosis (Other)	0.000	0.997	0.003
M19.26 Other secondary arthrosis of other joints-Lower leg	0.000	0.997	0.003
M19.25 Other secondary arthrosis (Pelvic region and thigh)	0.000	0.997	0.003
M19.24 Other secondary arthrosis (Hand)	0.000	0.997	0.003
M19.23 Other secondary arthrosis (Forearm)	0.000	0.997	0.003
M19.22 Other secondary arthrosis (Upper arm)	0.000	0.997	0.003
M19.20 Other secondary arthrosis (Multiple sites)	0.000	0.997	0.003
C02.9 Tongue, unspecified	0.000	0.997	0.003
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess	0.003	0.997	0.000
N88.8 Other specified noninflammatory disorders of cervix uteri	0.003	0.997	0.000
A49.9 Bacterial infection, unspecified	0.003	0.997	0.000
N60-N64 Disorders of breast	0.003	0.997	0.000
M19.27 Other secondary arthrosis (Ankle and foot)	0.000	0.997	0.003
A49.3 Mycoplasma infection, unspecified	0.003	0.997	0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
F43.2 Adjustment disorders	0.003	0.997	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.003	0.997	0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.000	0.997	0.003
S80.0 Contusion of knee	0.000	0.997	0.003
D72.8 Other specified disorders of white blood cells	0.003	0.997	0.000
C18.2 Ascending colon	0.000	0.997	0.003
R94.8 Abnormal results of function studies of other organs and systems	0.003	0.997	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.000	0.997	0.002
N50.1 Vascular disorders of male genital organs	0.000	0.997	0.003
R94 Abnormal results of function studies	0.003	0.997	0.000
R93.6 Abnormal findings on diagnostic imaging of limbs	0.000	0.997	0.003
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.000	0.997	0.003
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.003	0.997	0.000
F44.9 Dissociative [conversion] disorder, unspecified	0.003	0.997	0.000
O12.1 Gestational proteinuria	0.003	0.997	0.000
Z97.2 Presence of dental prosthetic device (complete)(partial)	0.003	0.997	0.000
C18 Malignant neoplasm of colon	0.000	0.997	0.003
F43 Reaction to severe stress, and adjustment disorders	0.003	0.997	0.000
D75.0 Familial erythrocytosis	0.002	0.997	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.002	0.997	0.000
M19.88 Other specified arthrosis (Other)	0.000	0.997	0.002
M19.86 Other specified arthrosis (Lower leg)	0.000	0.997	0.002
M19.85 Other specified arthrosis (Pelvic region and thigh)	0.000	0.997	0.002
M19.84 Other specified arthrosis (Hand)	0.000	0.997	0.002
M19.83 Other specified arthrosis (Forearm)	0.000	0.997	0.002
M19.82 Other specified arthrosis (Upper arm)	0.000	0.997	0.002
M19.81 Other specified arthrosis (Shoulder region)	0.000	0.997	0.002
M19.80 Other specified arthrosis (Multiple sites)	0.000	0.997	0.002
M19.1 Posttraumatic arthrosis of other joints	0.000	0.997	0.003
M19.89 Other specified arthrosis (Site unspecified)	0.000	0.997	0.002
C18.1 Appendix	0.000	0.997	0.003
D73 Diseases of spleen	0.003	0.997	0.000
A49.0 Staphylococcal infection, unspecified	0.003	0.997	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.000	0.997	0.002
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.000	0.997	0.002
Z97.3 Presence of spectacles and contact lenses	0.002	0.997	0.000
F44 Dissociative [conversion] disorders	0.003	0.997	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.003	0.997	0.000
M17.1 Other primary gonarthrosis	0.003	0.997	0.000
N45 Orchitis and epididymitis	0.003	0.997	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.000	0.998	0.002
R94.2 Abnormal results of pulmonary function studies	0.002	0.998	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.000	0.998	0.002
C41.0 Bones of skull and face	0.002	0.998	0.000
S46.3 Injury of muscle and tendon of triceps	0.000	0.998	0.002
C41.9 Bone and articular cartilage, unspecified	0.002	0.998	0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.000	0.998	0.002
Z97.4 Presence of external hearing-aid	0.002	0.998	0.000
D35.0 Adrenal gland	0.002	0.998	0.000
F43.9 Reaction to severe stress, unspecified	0.002	0.998	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.000	0.998	0.002
D73.4 Cyst of spleen	0.002	0.998	0.000
M19.0 Primary arthrosis of other joints	0.000	0.998	0.002
Z97.1 Presence of artificial limb (complete)(partial)	0.002	0.998	0.000
M19.87 Other specified arthrosis (Ankle and foot)	0.000	0.998	0.002
A49.1 Streptococcal infection, unspecified	0.002	0.998	0.000
H10.4 Chronic conjunctivitis	0.002	0.998	0.000
I05 Rheumatic mitral valve diseases	0.002	0.998	0.000
M19.14 Post-traumatic arthrosis of other joints (Hand)	0.000	0.998	0.002
E53.9 Vitamin B deficiency, unspecified	0.000	0.998	0.002
F42.9 Obsessive-compulsive disorder, unspecified	0.002	0.998	0.000
F44.8 Other dissociative [conversion] disorders	0.002	0.998	0.000
M17.3 Other posttraumatic gonarthrosis	0.002	0.998	0.000
S22.30 Fracture of rib (closed)	0.002	0.998	0.000
C18.8 Overlapping lesion of colon	0.000	0.998	0.002
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
K70.9 Alcoholic liver disease, unspecified	0.000	0.998	0.002
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.002	0.998	0.000
S81.8 Open wound of other parts of lower leg	0.002	0.998	0.000
F42 Obsessive-compulsive disorder	0.002	0.998	0.000
F44.4 Dissociative motor disorders	0.002	0.998	0.000
D75.2 Essential thrombocytosis	0.002	0.998	0.000
F43.1 Posttraumatic stress disorder	0.002	0.998	0.000
D75.1 Secondary polycythaemia	0.002	0.998	0.000
C18.5 Splenic flexure	0.000	0.998	0.002
D73.3 Abscess of spleen	0.002	0.998	0.000
F43.8 Other reactions to severe stress	0.002	0.998	0.000
F43.0 Acute stress reaction	0.002	0.998	0.000
Q21.0 Ventricular septal defect	0.002	0.998	0.000
M19.08 Primary arthrosis of other joints (Other)	0.000	0.998	0.002
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)	0.000	0.998	0.002
M19.18 Post-traumatic arthrosis of other joints (Other)	0.000	0.998	0.002
M19.16 Post-traumatic arthrosis of other joints-Lower leg	0.000	0.998	0.002
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)	0.000	0.998	0.002
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)	0.000	0.998	0.002
O12.0 Gestational oedema	0.002	0.998	0.000
Y54.0 Mineralocorticoids	0.002	0.998	0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites	0.002	0.998	0.000
D73.9 Disease of spleen, unspecified	0.002	0.998	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.002	0.998	0.000
H59.0 Vitreous syndrome following cataract surgery	0.000	0.998	0.002
R94.0 Abnormal results of function studies of central nervous system	0.002	0.998	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.002	0.998	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.002	0.998	0.000
D73.2 Chronic congestive splenomegaly	0.002	0.998	0.000
R94.7 Abnormal results of other endocrine function studies	0.002	0.998	0.000
F44.7 Mixed dissociative [conversion] disorders	0.002	0.998	0.000
F44.6 Dissociative anaesthesia and sensory loss	0.002	0.998	0.000
F44.5 Dissociative convulsions	0.002	0.998	0.000
F44.3 Trance and possession disorders	0.002	0.998	0.000
F44.2 Dissociative stupor	0.002	0.998	0.000
F44.1 Dissociative fugue	0.002	0.998	0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.002	0.998	0.000
M19.12 Post-traumatic arthrosis of other joints (Upper arm)	0.000	0.998	0.002
F45.4 Persistent somatoform pain disorder	0.002	0.998	0.000
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.000	0.998	0.002
F42.2 Mixed obsessional thoughts and acts	0.002	0.998	0.000
M23.9 Internal derangement of knee, unspecified	0.002	0.998	0.000
F45 Somatoform disorders	0.002	0.998	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.002	0.998	0.000
C18.4 Transverse colon	0.000	0.998	0.002
Y54.5 Other diuretics	0.002	0.998	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.002	0.998	0.000
F44.0 Dissociative amnesia	0.002	0.998	0.000
O12.2 Gestational oedema with proteinuria	0.002	0.998	0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.000	0.998	0.002
C41.2 Vertebral column	0.002	0.998	0.000
D22.4 Melanocytic naevi of scalp and neck	0.000	0.998	0.002
D39.1 Ovary	0.002	0.998	0.000
D68.6 Other Thrombophilia	0.002	0.998	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.002	0.998	0.000
S89.9 Unspecified injury of lower leg	0.002	0.998	0.000
C18.0 Caecum	0.000	0.998	0.002
F45.9 Somatoform disorder, unspecified	0.002	0.998	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.000	0.998	0.002
R94.6 Abnormal results of thyroid function studies	0.002	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
F48 Other neurotic disorders	0.002	0.998	0.000
S81 Open wound of lower leg	0.002	0.998	0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.000	0.998	0.002
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.002	0.998	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.002	0.998	0.000
C02.1 Border of tongue	0.000	0.998	0.002
F45.3 Somatoform autonomic dysfunction	0.002	0.998	0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
D30.3 Bladder	0.000	0.998	0.002
I05.8 Other mitral valve diseases	0.002	0.998	0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.000	0.998	0.002
S81.0 Open wound of knee	0.002	0.998	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.000	0.998	0.002
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.000	0.998	0.002
Y44.2 Anticoagulants	0.002	0.998	0.000
Y49.2 Other and unspecified antidepressants	0.002	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.002	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.998	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.998	0.002
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.000	0.998	0.002
F42.8 Other obsessive-compulsive disorders	0.002	0.998	0.000
F42.1 Predominantly compulsive acts [obsessional rituals]	0.002	0.998	0.000
N85.6 Intra-uterine synechiae	0.002	0.998	0.000
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)	0.002	0.998	0.000
M65.14 Other infective (teno)synovitis (Hand)	0.000	0.998	0.002
D73.8 Other diseases of spleen	0.002	0.998	0.000
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)	0.002	0.998	0.000
F45.0 Somatisation disorder	0.002	0.998	0.000
I05.1 Rheumatic mitral insufficiency	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
Z97.0 Presence of artificial eye	0.002	0.998	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.000	0.998	0.002
Y54.7 Agents affecting calcification	0.002	0.998	0.000
C80 Malignant neoplasm without specification of site	0.002	0.998	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.000	0.998	0.002
C41.8 Overlapping lesion of bone and articular cartilage	0.002	0.998	0.000
C41.3 Ribs, sternum and clavicle	0.002	0.998	0.000
C41.1 Mandible	0.002	0.998	0.000
D73.1 Hypersplenism	0.002	0.998	0.000
F48.0 Neurasthenia	0.002	0.998	0.000
I05.2 Mitral stenosis with insufficiency	0.002	0.998	0.000
H16.0 Corneal ulcer	0.000	0.998	0.002
F42.0 Predominantly obsessional thoughts or ruminations	0.002	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
C80.9 Malignant neoplasm, unspecified	0.002	0.998	0.000
N85.0 Endometrial glandular hyperplasia	0.002	0.998	0.000
Y44 Agents primarily affecting blood constituents	0.002	0.998	0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.002	0.998	0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.002	0.998	0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.002	0.998	0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.002	0.998	0.000
F45.2 Hypochondriacal disorder	0.002	0.998	0.000
F45.1 Undifferentiated somatoform disorder	0.002	0.998	0.000
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)	0.002	0.998	0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis	0.002	0.998	0.000
Z11.4 Special screening examination for human immunodeficiency virus [HIV]	0.002	0.998	0.000
I05.0 Mitral stenosis	0.002	0.998	0.000
Q24.8 Other specified congenital malformations of heart	0.002	0.998	0.000
S81.9 Open wound of lower leg, part unspecified	0.002	0.998	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.002	0.998	0.000
D23.4 Skin of scalp and neck	0.002	0.998	0.000
F48.9 Neurotic disorder, unspecified	0.002	0.998	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.002	0.998	0.000
Y44.6 Natural blood and blood products	0.002	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
C41.4 Pelvic bones, sacrum and coccyx	0.001	0.998	0.000
F48.8 Other specified neurotic disorders	0.001	0.998	0.000
F48.1 Depersonalisation-derealisation syndrome	0.001	0.998	0.000
Q05.9 Spina bifida, unspecified	0.002	0.998	0.000
S81.7 Multiple open wounds of lower leg	0.002	0.998	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.002	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
N85 Other noninflammatory disorders of uterus, except cervix	0.002	0.998	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.000	0.998	0.002
R09.2 Respiratory arrest	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
C02.8 Overlapping lesion of tongue	0.000	0.998	0.001
C02.3 Anterior two-thirds of tongue, part unspecified	0.000	0.998	0.001
C02.2 Ventral surface of tongue	0.000	0.998	0.002
C02.0 Dorsal surface of tongue	0.000	0.998	0.001
D73.5 Infarction of spleen	0.001	0.998	0.000
R94.4 Abnormal results of kidney function studies	0.002	0.998	0.000
Y49.9 Psychotropic drug, unspecified	0.001	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.001	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.001	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.001	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.001	0.998	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.000	0.998	0.002
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.002	0.998	0.000
S90.8 Other superficial injuries of ankle and foot	0.000	0.998	0.002
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.001	0.998	0.000
I77.1 Stricture of artery	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations