TreeWAS – Variant ID: rs3873385

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	0.000	0.000	1.000
L40 Psoriasis	0.000	0.000	1.000
L40.5 Arthropathic psoriasis	0.000	0.001	0.999
L40.0 Psoriasis vulgaris	0.000	0.108	0.892
L40.4 Guttate psoriasis	0.000	0.283	0.717
L40.3 Pustulosis palmaris et plantaris	0.000	0.283	0.717
L40.2 Acrodermatitis continua	0.000	0.283	0.717
L40.1 Generalised pustular psoriasis	0.000	0.283	0.717
L40.8 Other psoriasis	0.000	0.312	0.688
E03 Other hypothyroidism	0.567	0.432	0.001
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.481	0.518	0.001
K90 Intestinal malabsorption	0.000	0.561	0.439
E03.5 Myxoedema coma	0.406	0.593	0.001
E03.4 Atrophy of thyroid (acquired)	0.406	0.593	0.001
E03.3 Postinfectious hypothyroidism	0.406	0.593	0.001
E03.1 Congenital hypothyroidism without goitre	0.406	0.593	0.001
E03.0 Congenital hypothyroidism with diffuse goitre	0.406	0.593	0.001
E03.8 Other specified hypothyroidism	0.396	0.603	0.001
K90.9 Intestinal malabsorption, unspecified	0.000	0.661	0.339
L40-L45 Papulosquamous disorders	0.000	0.670	0.330
K90.3 Pancreatic steatorrhoea	0.000	0.685	0.315
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.685	0.315
K90.1 Tropical sprue	0.000	0.685	0.315
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.697	0.302
K90.8 Other intestinal malabsorption	0.000	0.704	0.296
M25.5 Pain in joint	0.000	0.736	0.264
M25.55 Pain in joint (Pelvic region and thigh)	0.000	0.744	0.256
M25.54 Pain in joint (Hand)	0.000	0.746	0.254
M25 Other joint disorders, not elsewhere classified	0.000	0.756	0.244
M25.51 Pain in joint (Shoulder region)	0.000	0.757	0.243
L44 Other papulosquamous disorders	0.000	0.763	0.237
L41 Parapsoriasis	0.000	0.763	0.237
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.763	0.237
M25.58 Pain in joint (Other)	0.000	0.767	0.233
M25.59 Pain in joint (Site unspecified)	0.000	0.770	0.230
M25.6 Stiffness of joint, not elsewhere classified	0.000	0.772	0.228
L42 Pityriasis rosea	0.000	0.779	0.221
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.000	0.780	0.220
L43 Lichen planus	0.000	0.787	0.213
M25.9 Joint disorder, unspecified	0.000	0.789	0.211
M25.8 Other specified joint disorders	0.000	0.797	0.203
M25.7 Osteophyte	0.000	0.798	0.202
M25.50 Pain in joint (Multiple sites)	0.000	0.803	0.197
M25.96 Joint disorder, unspecified (Lower leg)	0.000	0.808	0.192
M25.84 Other specified joint disorders (Hand)	0.000	0.811	0.189
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.000	0.820	0.180
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.000	0.821	0.179
M25.3 Other instability of joint	0.000	0.823	0.177
M25.0 Haemarthrosis	0.000	0.824	0.176
M25.2 Flail joint	0.000	0.825	0.175
M25.1 Fistula of joint	0.000	0.825	0.175
M25.76 Osteophyte (Lower leg)	0.000	0.826	0.174
L41.9 Parapsoriasis, unspecified	0.000	0.830	0.170
L41.8 Other parapsoriasis	0.000	0.830	0.170
L41.5 Retiform parapsoriasis	0.000	0.830	0.170
L41.4 Large plaque parapsoriasis	0.000	0.830	0.170
L41.3 Small plaque parapsoriasis	0.000	0.830	0.170
L41.2 Lymphomatoid papulosis	0.000	0.830	0.170
L41.1 Pityriasis lichenoides chronica	0.000	0.830	0.170
L41.0 Pityriasis lichenoides et varioliformis acuta	0.000	0.830	0.170
L44.9 Papulosquamous disorder, unspecified	0.000	0.830	0.170
L44.8 Other specified papulosquamous disorders	0.000	0.830	0.170
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.000	0.830	0.170
L44.3 Lichen ruber moniliformis	0.000	0.830	0.170
L44.2 Lichen striatus	0.000	0.830	0.170
L44.1 Lichen nitidus	0.000	0.830	0.170
L44.0 Pityriasis rubra pilaris	0.000	0.830	0.170
M25.77 Osteophyte (Ankle and foot)	0.000	0.831	0.169
M25.52 Pain in joint (Upper arm)	0.000	0.832	0.168
M25.74 Osteophyte (Hand)	0.000	0.833	0.167
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.000	0.836	0.164
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.836	0.164
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.000	0.836	0.164
M25.97 Joint disorder, unspecified (Ankle and foot)	0.000	0.837	0.163
L43.8 Other lichen planus	0.000	0.838	0.162
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.000	0.840	0.159
M25.71 Osteophyte (Shoulder region)	0.000	0.841	0.159
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.000	0.841	0.158
M25.53 Pain in joint (Forearm)	0.000	0.843	0.157
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.000	0.845	0.155
M25.57 Pain in joint (Ankle and foot)	0.000	0.846	0.154
M25.86 Other specified joint disorders (Lower leg)	0.000	0.847	0.153
L43.3 Subacute (active) lichen planus	0.000	0.847	0.153
L43.2 Lichenoid drug reaction	0.000	0.847	0.153
L43.1 Bullous lichen planus	0.000	0.847	0.153
L43.0 Hypertrophic lichen planus	0.000	0.847	0.153
M25.99 Joint disorder, unspecified (Site unspecified)	0.000	0.848	0.151
M25.98 Joint disorder, unspecified (Other)	0.000	0.848	0.151
M25.94 Joint disorder, unspecified (Hand)	0.000	0.848	0.151
M25.93 Joint disorder, unspecified (Forearm)	0.000	0.848	0.151
M25.92 Joint disorder, unspecified (Upper arm)	0.000	0.848	0.151
M25.90 Joint disorder, unspecified (Multiple sites)	0.000	0.848	0.151
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.851	0.148
M25.37 Other instability of joint (Ankle and foot)	0.000	0.853	0.147
M25.89 Other specified joint disorders (Site unspecified)	0.000	0.854	0.146
M25.82 Other specified joint disorders (Upper arm)	0.000	0.854	0.146
M25.80 Other specified joint disorders (Multiple sites)	0.000	0.854	0.146
M25.79 Osteophyte (Site unspecified)	0.000	0.855	0.145
M25.73 Osteophyte (Forearm)	0.000	0.855	0.145
M25.70 Osteophyte (Multiple sites)	0.000	0.855	0.145
M25.91 Joint disorder, unspecified (Shoulder region)	0.000	0.855	0.145
M25.81 Other specified joint disorders (Shoulder region)	0.000	0.856	0.144
M25.72 Osteophyte (Upper arm)	0.000	0.863	0.137
M25.83 Other specified joint disorders (Forearm)	0.000	0.864	0.136
M25.31 Other instability of joint (Shoulder region)	0.000	0.865	0.135
M25.36 Other instability of joint (Lower leg)	0.000	0.870	0.130
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.000	0.872	0.128
M25.06 Haemarthrosis (Lower leg)	0.000	0.873	0.127
M25.39 Other instability of joint (Site unspecified)	0.000	0.873	0.127
M25.38 Other instability of joint (Other)	0.000	0.873	0.127
M25.35 Other instability of joint (Pelvic region and thigh)	0.000	0.873	0.127
M25.32 Other instability of joint (Upper arm)	0.000	0.873	0.127
M25.30 Other instability of joint (Multiple sites)	0.000	0.873	0.127
M25.09 Haemarthrosis (Site unspecified)	0.000	0.874	0.126
M25.08 Haemarthrosis (Other)	0.000	0.874	0.126
M25.07 Haemarthrosis (Ankle and foot)	0.000	0.874	0.126
M25.05 Haemarthrosis (Pelvic region and thigh)	0.000	0.874	0.126
M25.04 Haemarthrosis (Hand)	0.000	0.874	0.126
M25.03 Haemarthrosis (Forearm)	0.000	0.874	0.126
M25.02 Haemarthrosis (Upper arm)	0.000	0.874	0.126
M25.01 Haemarthrosis (Shoulder region)	0.000	0.874	0.126
M25.00 Haemarthrosis (Multiple sites)	0.000	0.874	0.126
M25.19 Fistula of joint (Site unspecified)	0.000	0.874	0.126
M25.18 Fistula of joint (Other)	0.000	0.874	0.126
M25.17 Fistula of joint (Ankle and foot)	0.000	0.874	0.126
M25.16 Fistula of joint (Lower leg)	0.000	0.874	0.126
M25.15 Fistula of joint (Pelvic region and thigh)	0.000	0.874	0.126
M25.14 Fistula of joint (Hand)	0.000	0.874	0.126
M25.13 Fistula of joint (Forearm)	0.000	0.874	0.126
M25.12 Fistula of joint (Upper arm)	0.000	0.874	0.126
M25.11 Fistula of joint (Shoulder region)	0.000	0.874	0.126
M25.10 Fistula of joint (Multiple sites)	0.000	0.874	0.126
M25.29 Flail joint (Site unspecified)	0.000	0.874	0.126
M25.28 Flail joint (Other)	0.000	0.874	0.126
M25.27 Flail joint (Ankle and foot)	0.000	0.874	0.126
M25.26 Flail joint (Lower leg)	0.000	0.874	0.126
M25.25 Flail joint (Pelvic region and thigh)	0.000	0.874	0.126
M25.24 Flail joint (Hand)	0.000	0.874	0.126
M25.23 Flail joint (Forearm)	0.000	0.874	0.126
M25.22 Flail joint (Upper arm)	0.000	0.874	0.126
M25.21 Flail joint (Shoulder region)	0.000	0.874	0.126
M25.20 Flail joint (Multiple sites)	0.000	0.874	0.126
M25.4 Effusion of joint	0.000	0.876	0.124
M25.88 Other specified joint disorders (Other)	0.000	0.877	0.123
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.881	0.119
M25.87 Other specified joint disorders (Ankle and foot)	0.000	0.882	0.118
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.000	0.882	0.118
L43.9 Lichen planus, unspecified	0.000	0.887	0.113
M25.33 Other instability of joint (Forearm)	0.000	0.889	0.110
M25.34 Other instability of joint (Hand)	0.000	0.895	0.105
D75 Other diseases of blood and blood-forming organs	0.000	0.901	0.099
M25.43 Effusion of joint (Forearm)	0.000	0.903	0.097
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.904	0.096
M25.56 Pain in joint (Lower leg)	0.000	0.905	0.095
M25.46 Effusion of joint (Lower leg)	0.000	0.905	0.095
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.907	0.093
D70 Agranulocytosis	0.000	0.907	0.093
M25.49 Effusion of joint (Site unspecified)	0.000	0.911	0.089
M25.48 Effusion of joint (Other)	0.000	0.911	0.089
M25.41 Effusion of joint (Shoulder region)	0.000	0.911	0.089
D75.2 Essential thrombocytosis	0.000	0.912	0.088
D72 Other disorders of white blood cells	0.000	0.913	0.087
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.914	0.086
M25.44 Effusion of joint (Hand)	0.000	0.914	0.085
M25.45 Effusion of joint (Pelvic region and thigh)	0.000	0.917	0.083
D75.1 Secondary polycythaemia	0.000	0.917	0.083
D72.8 Other specified disorders of white blood cells	0.000	0.918	0.082
M25.42 Effusion of joint (Upper arm)	0.000	0.918	0.082
M25.40 Effusion of joint (Multiple sites)	0.000	0.920	0.080
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.929	0.071
D74 Methaemoglobinaemia	0.000	0.931	0.069
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.931	0.069
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.931	0.069
D75.0 Familial erythrocytosis	0.000	0.931	0.069
D73 Diseases of spleen	0.000	0.931	0.069
D72.9 Disorder of white blood cells, unspecified	0.000	0.938	0.062
D72.0 Genetic anomalies of leukocytes	0.000	0.938	0.062
M25.78 Osteophyte (Other)	0.000	0.938	0.062
D86 Sarcoidosis	0.000	0.942	0.058
M25.47 Effusion of joint (Ankle and foot)	0.000	0.943	0.057
D86.9 Sarcoidosis, unspecified	0.000	0.944	0.056
D73.0 Hyposplenism	0.000	0.945	0.055
D73.8 Other diseases of spleen	0.000	0.945	0.055
D76.3 Other histiocytosis syndromes	0.000	0.947	0.053
D86.8 Sarcoidosis of other and combined sites	0.000	0.949	0.051
D76.2 Haemophagocytic syndrome, infection-associated	0.000	0.949	0.051
D76.1 Haemophagocytic lymphohistiocytosis	0.000	0.949	0.051
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.000	0.949	0.051
D86.0 Sarcoidosis of lung	0.000	0.949	0.051
D72.1 Eosinophilia	0.000	0.950	0.050
D74.9 Methaemoglobinaemia, unspecified	0.000	0.950	0.050
D74.8 Other methaemoglobinaemias	0.000	0.950	0.050
D74.0 Congenital methaemoglobinaemia	0.000	0.950	0.050
D73.9 Disease of spleen, unspecified	0.000	0.950	0.050
D73.3 Abscess of spleen	0.000	0.950	0.050
D73.2 Chronic congestive splenomegaly	0.000	0.950	0.050
D73.1 Hypersplenism	0.000	0.950	0.050
D80-D89 Certain disorders involving the immune mechanism	0.000	0.951	0.049
D86.1 Sarcoidosis of lymph nodes	0.000	0.951	0.049
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.953	0.047
D73.5 Infarction of spleen	0.000	0.954	0.046
D86.3 Sarcoidosis of skin	0.000	0.956	0.044
K90-K93 Other diseases of the digestive system	0.000	0.960	0.040
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.960	0.040
D73.4 Cyst of spleen	0.000	0.961	0.038
D82 Immunodeficiency associated with other major defects	0.000	0.964	0.035
D81 Combined immunodeficiencies	0.000	0.964	0.035
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.966	0.034
D83 Common variable immunodeficiency	0.000	0.966	0.034
D84 Other immunodeficiencies	0.000	0.967	0.033
D55-D59 Haemolytic anaemias	0.000	0.968	0.031
M20-M25 Other joint disorders	0.000	0.971	0.029
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.971	0.029
D80 Immunodeficiency with predominantly antibody defects	0.000	0.971	0.028
D81.9 Combined immunodeficiency, unspecified	0.000	0.974	0.026
D81.8 Other combined immunodeficiencies	0.000	0.974	0.026
D81.7 Major histocompatibility complex class II deficiency	0.000	0.974	0.026
D81.6 Major histocompatibility complex class I deficiency	0.000	0.974	0.026
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.974	0.026
D81.4 Nezelof's syndrome	0.000	0.974	0.026
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.974	0.026
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.974	0.026
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.974	0.026
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.974	0.026
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.974	0.026
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.974	0.026
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.974	0.026
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.974	0.026
D82.2 Immunodeficiency with short-limbed stature	0.000	0.974	0.026
D82.1 Di George's syndrome	0.000	0.974	0.026
D82.0 Wiskott-Aldrich syndrome	0.000	0.974	0.026
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.975	0.025
D89.3 Immune reconstitution syndrome	0.000	0.975	0.025
D89.1 Cryoglobulinaemia	0.000	0.975	0.025
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.975	0.025
M21 Other acquired deformities of limbs	0.000	0.975	0.025
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.975	0.025
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.975	0.025
D83.8 Other common variable immunodeficiencies	0.000	0.975	0.024
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.975	0.024
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.975	0.024
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.975	0.024
D84.8 Other specified immunodeficiencies	0.000	0.976	0.024
D84.1 Defects in the complement system	0.000	0.976	0.024
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.976	0.024
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.976	0.024
M31 Other necrotising vasculopathies	0.000	0.976	0.024
M32 Systemic lupus erythematosus	0.000	0.977	0.023
M24 Other specific joint derangements	0.000	0.977	0.023
D57 Sickle-cell disorders	0.000	0.977	0.023
D55 Anaemia due to enzyme disorders	0.000	0.977	0.023
D83.9 Common variable immunodeficiency, unspecified	0.000	0.977	0.022
D58 Other hereditary haemolytic anaemias	0.000	0.978	0.022
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.978	0.022
M30 Polyarteritis nodosa and related conditions	0.000	0.978	0.022
D56 Thalassaemia	0.000	0.978	0.022
D84.9 Immunodeficiency, unspecified	0.000	0.978	0.022
D59 Acquired haemolytic anaemia	0.000	0.978	0.022
J98.4 Other disorders of lung	0.022	0.978	0.000
D50-D53 Nutritional anaemias	0.000	0.979	0.021
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.000	0.979	0.021
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.979	0.021
K93.1 Megacolon in Chagas' disease	0.000	0.979	0.021
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.979	0.021
M21.1 Varus deformity, not elsewhere classified	0.000	0.979	0.021
M21.3 Wrist or foot drop (acquired)	0.000	0.979	0.021
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.979	0.020
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.979	0.020
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.979	0.020
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.979	0.020
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.979	0.020
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.979	0.020
E00-E07 Disorders of thyroid gland	0.015	0.979	0.006
S64.4 Injury of digital nerve of other finger	0.020	0.980	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.000	0.980	0.020
M33 Dermatopolymyositis	0.000	0.980	0.020
M31.6 Other giant cell arteritis	0.000	0.980	0.020
M35 Other systemic involvement of connective tissue	0.000	0.980	0.020
M24.0 Loose body in joint	0.000	0.980	0.020
M34 Systemic sclerosis	0.000	0.980	0.020
C18.7 Sigmoid colon	0.019	0.981	0.000
M21.4 Flat foot [pes planus] (acquired)	0.000	0.981	0.019
M32.1 Systemic lupus erythematosus with organ or system involvement	0.000	0.981	0.019
M24.1 Other articular cartilage disorders	0.000	0.981	0.019
M21.0 Valgus deformity, not elsewhere classified	0.000	0.981	0.019
D66 Hereditary factor VIII deficiency	0.000	0.981	0.019
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.981	0.018
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.000	0.981	0.019
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.982	0.018
M21.9 Acquired deformity of limb, unspecified	0.000	0.982	0.018
M21.8 Other specified acquired deformities of limbs	0.000	0.982	0.018
M21.7 Unequal limb length (acquired)	0.000	0.982	0.018
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.000	0.982	0.018
C90.0 Multiple myeloma	0.000	0.982	0.018
D67 Hereditary factor IX deficiency	0.000	0.982	0.018
M35.3 Polymyalgia rheumatica	0.000	0.982	0.018
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.982	0.018
M24.4 Recurrent dislocation and subluxation of joint	0.000	0.982	0.018
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.982	0.017
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.982	0.017
M24.2 Disorder of ligament	0.000	0.982	0.018
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.982	0.017
M24.01 Loose body in joint (Shoulder region)	0.000	0.982	0.017
D51 Vitamin B12 deficiency anaemia	0.000	0.983	0.017
D58.9 Hereditary haemolytic anaemia, unspecified	0.000	0.983	0.017
M31.8 Other specified necrotising vasculopathies	0.000	0.983	0.017
M31.4 Aortic arch syndrome [Takayasu]	0.000	0.983	0.017
M31.2 Lethal midline granuloma	0.000	0.983	0.017
M31.1 Thrombotic microangiopathy	0.000	0.983	0.017
M31.0 Hypersensitivity angiitis	0.000	0.983	0.017
M24.8 Other specific joint derangements, not elsewhere classified	0.000	0.983	0.017
M32.9 Systemic lupus erythematosus, unspecified	0.000	0.983	0.017
M32.8 Other forms of systemic lupus erythematosus	0.000	0.983	0.017
M32.0 Drug-induced systemic lupus erythematosus	0.000	0.983	0.017
M24.9 Joint derangement, unspecified	0.000	0.983	0.017
M24.02 Loose body in joint (Upper arm)	0.000	0.983	0.017
D55.9 Anaemia due to enzyme disorder, unspecified	0.000	0.983	0.016
D55.8 Other anaemias due to enzyme disorders	0.000	0.983	0.016
D55.3 Anaemia due to disorders of nucleotide metabolism	0.000	0.983	0.016
D55.2 Anaemia due to disorders of glycolytic enzymes	0.000	0.983	0.016
D55.1 Anaemia due to other disorders of glutathione metabolism	0.000	0.983	0.016
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.000	0.983	0.016
D57.8 Other sickle-cell disorders	0.000	0.983	0.016
D57.3 Sickle-cell trait	0.000	0.983	0.016
D57.2 Double heterozygous sickling disorders	0.000	0.983	0.016
D57.1 Sickle-cell anaemia without crisis	0.000	0.983	0.016
D57.0 Sickle-cell anaemia with crisis	0.000	0.983	0.016
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.983	0.017
M24.6 Ankylosis of joint	0.000	0.983	0.017
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.984	0.016
D58.8 Other specified hereditary haemolytic anaemias	0.000	0.984	0.016
D58.2 Other haemoglobinopathies	0.000	0.984	0.016
D58.1 Hereditary elliptocytosis	0.000	0.984	0.016
D53 Other nutritional anaemias	0.000	0.984	0.016
M30.8 Other conditions related to polyarteritis nodosa	0.000	0.984	0.016
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.000	0.984	0.016
M30.2 Juvenile polyarteritis	0.000	0.984	0.016
D56.9 Thalassaemia, unspecified	0.000	0.984	0.016
D56.8 Other thalassaemias	0.000	0.984	0.016
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.000	0.984	0.016
D56.3 Thalassaemia trait	0.000	0.984	0.016
D56.2 Delta-beta thalassaemia	0.000	0.984	0.016
D56.0 Alpha thalassaemia	0.000	0.984	0.016
M21.6 Other acquired deformities of ankle and foot	0.000	0.984	0.016
D59.9 Acquired haemolytic anaemia, unspecified	0.000	0.984	0.016
D59.8 Other acquired haemolytic anaemias	0.000	0.984	0.016
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.000	0.984	0.016
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.000	0.984	0.016
D59.4 Other nonautoimmune haemolytic anaemias	0.000	0.984	0.016
D59.3 Haemolytic-uraemic syndrome	0.000	0.984	0.016
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.000	0.984	0.016
D59.0 Drug-induced autoimmune haemolytic anaemia	0.000	0.984	0.016
M31.9 Necrotising vasculopathy, unspecified	0.000	0.984	0.015
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.000	0.984	0.015
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.000	0.984	0.015
M36.3 Arthropathy in other blood disorders	0.000	0.984	0.015
M36.2 Haemophilic arthropathy	0.000	0.984	0.015
M36.1 Arthropathy in neoplastic disease	0.000	0.984	0.015
M36.0 Dermato(poly)myositis in neoplastic disease	0.000	0.984	0.015
J98 Other respiratory disorders	0.015	0.985	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.985	0.015
M35.7 Hypermobility syndrome	0.000	0.985	0.015
D56.1 Beta thalassaemia	0.000	0.985	0.015
M21.2 Flexion deformity	0.000	0.985	0.015
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.000	0.985	0.015
M21.18 Varus deformity, not elsewhere classified (Other)	0.000	0.985	0.015
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.985	0.015
M21.14 Varus deformity, not elsewhere classified (Hand)	0.000	0.985	0.015
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.000	0.985	0.015
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.000	0.985	0.015
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.000	0.985	0.015
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.000	0.985	0.015
M22 Disorders of patella	0.000	0.985	0.015
M33.2 Polymyositis	0.000	0.985	0.015
M21.39 Wrist or foot drop (acquired)-Site unspec	0.000	0.985	0.015
M21.38 Wrist or foot drop (acquired)-Other	0.000	0.985	0.015
M21.36 Wrist or foot drop (acquired)-Lower leg	0.000	0.985	0.015
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.000	0.985	0.015
M21.34 Wrist or foot drop (acquired) (Hand)	0.000	0.985	0.015
M21.33 Wrist or foot drop (acquired) (Forearm)	0.000	0.985	0.015
M21.32 Wrist or foot drop (acquired)-Upper arm	0.000	0.985	0.015
M21.31 Wrist or foot drop (acquired)-Shldr region	0.000	0.985	0.015
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.000	0.985	0.015
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.011	0.985	0.004
E00 Congenital iodine-deficiency syndrome	0.011	0.985	0.004
E02 Subclinical iodine-deficiency hypothyroidism	0.011	0.985	0.004
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.000	0.985	0.015
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.000	0.985	0.015
M30.0 Polyarteritis nodosa	0.000	0.985	0.015
M31.3 Wegener's granulomatosis	0.000	0.985	0.015
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.985	0.015
M24.27 Disorder of ligament (Ankle and foot)	0.000	0.985	0.015
F41.2 Mixed anxiety and depressive disorder	0.015	0.985	0.000
M24.7 Protrusio acetabuli	0.000	0.985	0.015
M33.9 Dermatopolymyositis, unspecified	0.000	0.985	0.015
M33.0 Juvenile dermatomyositis	0.000	0.985	0.015
M24.23 Disorder of ligament (Forearm)	0.000	0.985	0.015
M35.8 Other specified systemic involvement of connective tissue	0.000	0.985	0.015
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.985	0.015
D59.1 Other autoimmune haemolytic anaemias	0.000	0.985	0.015
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.000	0.985	0.015
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.985	0.015
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.985	0.015
M35.5 Multifocal fibrosclerosis	0.000	0.985	0.015
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.985	0.015
M31.7 Microscopic polyangiitis	0.000	0.985	0.014
D68 Other coagulation defects	0.000	0.985	0.015
M24.09 Loose body in joint (Site unspecified)	0.000	0.985	0.015
M24.08 Loose body in joint (Other)	0.000	0.985	0.015
M24.06 Loose body in joint-Lower leg	0.000	0.985	0.015
M24.05 Loose body in joint (Pelvic region and thigh)	0.000	0.985	0.015
M24.04 Loose body in joint (Hand)	0.000	0.985	0.015
M24.03 Loose body in joint (Forearm)	0.000	0.985	0.015
M24.00 Loose body in joint (Multiple sites)	0.000	0.985	0.015
D58.0 Hereditary spherocytosis	0.000	0.985	0.014
M34.9 Systemic sclerosis, unspecified	0.000	0.985	0.015
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.985	0.015
J98.1 Pulmonary collapse	0.015	0.985	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.985	0.014
M34.0 Progressive systemic sclerosis	0.000	0.985	0.014
M24.5 Contracture of joint	0.000	0.986	0.014
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.000	0.986	0.014
J98.8 Other specified respiratory disorders	0.014	0.986	0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.000	0.986	0.014
M21.48 Flat foot [pes planus] (acquired)-Other	0.000	0.986	0.014
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.000	0.986	0.014
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.000	0.986	0.014
M21.44 Flat foot [pes planus] (acquired)-Hand	0.000	0.986	0.014
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.000	0.986	0.014
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.000	0.986	0.014
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.000	0.986	0.014
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.000	0.986	0.014
M24.19 Other articular cartilage disorders (Site unspecified)	0.000	0.986	0.014
M24.18 Other articular cartilage disorders (Other)	0.000	0.986	0.014
M24.14 Other articular cartilage disorders (Hand)	0.000	0.986	0.014
M24.12 Other articular cartilage disorders (Upper arm)	0.000	0.986	0.014
M24.10 Other articular cartilage disorders (Multiple sites)	0.000	0.986	0.014
M24.21 Disorder of ligament (Shoulder region)	0.000	0.986	0.014
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.000	0.986	0.014
M21.08 Valgus deformity, not elsewhere classified (Other)	0.000	0.986	0.014
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.986	0.014
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.000	0.986	0.014
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.000	0.986	0.014
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.000	0.986	0.014
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.000	0.986	0.014
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.000	0.986	0.014
M34.1 CR(E)ST syndrome	0.000	0.986	0.014
M34.8 Other forms of systemic sclerosis	0.000	0.986	0.014
M33.1 Other dermatomyositis	0.000	0.986	0.014
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.986	0.014
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.000	0.986	0.013
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.000	0.986	0.013
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.000	0.986	0.013
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.000	0.986	0.013
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.000	0.986	0.013
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.000	0.986	0.013
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.000	0.986	0.013
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.000	0.986	0.013
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.000	0.986	0.013
S64 Injury of nerves at wrist and hand level	0.013	0.986	0.000
M21.79 Unequal limb length (acquired) (Site unspecified)	0.000	0.987	0.013
M21.78 Unequal limb length (acquired)-Other	0.000	0.987	0.013
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.000	0.987	0.013
M21.76 Unequal limb length (acquired) (Lower leg)	0.000	0.987	0.013
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.000	0.987	0.013
M21.74 Unequal limb length (acquired) (Hand)	0.000	0.987	0.013
M21.73 Unequal limb length (acquired) (Forearm)	0.000	0.987	0.013
M21.72 Unequal limb length (acquired) (Upper arm)	0.000	0.987	0.013
M21.71 Unequal limb length (acquired)-Shldr region	0.000	0.987	0.013
M21.70 Unequal limb length (acquired) (Multiple sites)	0.000	0.987	0.013
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.000	0.987	0.013
M21.88 Other specified acquired deformities of limbs-Other	0.000	0.987	0.013
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.000	0.987	0.013
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.000	0.987	0.013
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.000	0.987	0.013
M21.84 Other specified acquired deformities of limbs (Hand)	0.000	0.987	0.013
M21.83 Other specified acquired deformities of limbs (Forearm)	0.000	0.987	0.013
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.000	0.987	0.013
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.000	0.987	0.013
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.000	0.987	0.013
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.000	0.987	0.013
M21.98 Acquired deformity of limb, unspecified-Other	0.000	0.987	0.013
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.000	0.987	0.013
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.000	0.987	0.013
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.000	0.987	0.013
M21.94 Acquired deformity of limb, unspecified (Hand)	0.000	0.987	0.013
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.000	0.987	0.013
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.000	0.987	0.013
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.000	0.987	0.013
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.000	0.987	0.013
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.000	0.987	0.013
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.000	0.987	0.013
M24.13 Other articular cartilage disorders (Forearm)	0.000	0.987	0.013
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.000	0.987	0.013
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.000	0.987	0.013
N63 Unspecified lump in breast	0.000	0.987	0.013
E07 Other disorders of thyroid	0.010	0.987	0.003
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.000	0.987	0.013

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations