TreeWAS – Variant ID: rs3891355

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M25.77 Osteophyte (Ankle and foot)	0.038	0.962	0.000
M35.0 Sicca syndrome [Sjogren]	0.028	0.972	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.974	0.026
T43.2 Other and unspecified antidepressants	0.000	0.974	0.026
M25.7 Osteophyte	0.026	0.974	0.000
L91.8 Other hypertrophic disorders of skin	0.025	0.975	0.000
M35 Other systemic involvement of connective tissue	0.025	0.975	0.000
S61.8 Open wound of other parts of wrist and hand	0.000	0.975	0.025
T42.4 Benzodiazepines	0.000	0.975	0.025
M47.99 Spondylosis, unspecified (Site unspecified)	0.000	0.976	0.024
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.976	0.024
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.976	0.024
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.976	0.024
M22 Disorders of patella	0.024	0.976	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.976	0.024
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.977	0.023
M20-M25 Other joint disorders	0.023	0.977	0.000
M25 Other joint disorders, not elsewhere classified	0.023	0.977	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.978	0.022
M22.2 Patellofemoral disorders	0.022	0.978	0.000
L91 Hypertrophic disorders of skin	0.021	0.979	0.000
M25.71 Osteophyte (Shoulder region)	0.021	0.979	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.980	0.020
M35.3 Polymyalgia rheumatica	0.020	0.980	0.000
M34 Systemic sclerosis	0.020	0.980	0.000
T39.0 Salicylates	0.000	0.980	0.020
M22.4 Chondromalacia patellae	0.020	0.980	0.000
M22.8 Other disorders of patella	0.020	0.980	0.000
T43.6 Psychostimulants with abuse potential	0.000	0.980	0.020
M25.4 Effusion of joint	0.020	0.980	0.000
M25.78 Osteophyte (Other)	0.019	0.981	0.000
T43.9 Psychotropic drug, unspecified	0.000	0.981	0.019
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.981	0.019
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.981	0.019
M25.75 Osteophyte (Pelvic region and thigh)	0.019	0.981	0.000
M35.7 Hypermobility syndrome	0.019	0.981	0.000
M25.79 Osteophyte (Site unspecified)	0.019	0.981	0.000
M25.73 Osteophyte (Forearm)	0.018	0.981	0.000
M25.70 Osteophyte (Multiple sites)	0.018	0.981	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.981	0.018
M24 Other specific joint derangements	0.018	0.981	0.000
M25.46 Effusion of joint (Lower leg)	0.018	0.982	0.000
M22.0 Recurrent dislocation of patella	0.018	0.982	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.018	0.982	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.018	0.982	0.000
M35.5 Multifocal fibrosclerosis	0.018	0.982	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.018	0.982	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.982	0.018
T36 Poisoning by systemic antibiotics	0.000	0.982	0.018
M25.74 Osteophyte (Hand)	0.018	0.982	0.000
M25.9 Joint disorder, unspecified	0.018	0.982	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.982	0.018
M25.6 Stiffness of joint, not elsewhere classified	0.018	0.982	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.982	0.018
L98.8 Other specified disorders of skin and subcutaneous tissue	0.018	0.982	0.000
M35.8 Other specified systemic involvement of connective tissue	0.018	0.982	0.000
M34.9 Systemic sclerosis, unspecified	0.018	0.982	0.000
M31 Other necrotising vasculopathies	0.018	0.982	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.982	0.017
M35.2 Behcet's disease	0.017	0.983	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.983	0.017
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.983	0.017
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.983	0.017
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.983	0.017
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.983	0.017
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.983	0.017
T42.3 Barbiturates	0.000	0.983	0.017
T42.2 Succinimides and oxazolidinediones	0.000	0.983	0.017
M22.1 Recurrent subluxation of patella	0.017	0.983	0.000
M22.9 Disorder of patella, unspecified	0.017	0.983	0.000
M22.3 Other derangements of patella	0.017	0.983	0.000
M30 Polyarteritis nodosa and related conditions	0.017	0.983	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.017	0.983	0.000
L85.9 Epidermal thickening, unspecified	0.017	0.983	0.000
T42.0 Hydantoin derivatives	0.000	0.983	0.017
L91.0 Keloid scar	0.017	0.983	0.000
T39.4 Antirheumatics, not elsewhere classified	0.000	0.983	0.017
T39.2 Pyrazolone derivatives	0.000	0.983	0.017
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.983	0.017
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.017	0.983	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.983	0.017
M25.2 Flail joint	0.016	0.983	0.000
M25.1 Fistula of joint	0.016	0.983	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.984	0.016
M32 Systemic lupus erythematosus	0.016	0.984	0.000
L85 Other epidermal thickening	0.016	0.984	0.000
L80 Vitiligo	0.016	0.984	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.984	0.016
M25.91 Joint disorder, unspecified (Shoulder region)	0.016	0.984	0.000
M35.1 Other overlap syndromes	0.016	0.984	0.000
M25.0 Haemarthrosis	0.016	0.984	0.000
L83 Acanthosis nigricans	0.016	0.984	0.000
M24.7 Protrusio acetabuli	0.016	0.984	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.016	0.984	0.000
M24.5 Contracture of joint	0.016	0.984	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.985	0.015
M34.8 Other forms of systemic sclerosis	0.015	0.985	0.000
M21 Other acquired deformities of limbs	0.015	0.985	0.000
L95 Vasculitis limited to skin, not elsewhere classified	0.015	0.985	0.000
M34.1 CR(E)ST syndrome	0.015	0.985	0.000
L93 Lupus erythematosus	0.015	0.985	0.000
M33 Dermatopolymyositis	0.015	0.985	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.015	0.985	0.000
M25.47 Effusion of joint (Ankle and foot)	0.015	0.985	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.985	0.015
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.985	0.015
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.985	0.015
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.985	0.015
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.985	0.015
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.985	0.015
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.985	0.015
T44.0 Anticholinesterase agents	0.000	0.985	0.015
M25.3 Other instability of joint	0.015	0.985	0.000
M31.9 Necrotising vasculopathy, unspecified	0.015	0.985	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.015	0.985	0.000
M34.0 Progressive systemic sclerosis	0.015	0.985	0.000
T42.1 Iminostilbenes	0.000	0.985	0.015
M24.51 Contracture of joint (Shoulder region)	0.015	0.985	0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.015	0.985	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.015	0.985	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.985	0.014
L91.9 Hypertrophic disorder of skin, unspecified	0.014	0.986	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.986	0.014
T45.0 Antiallergic and antiemetic drugs	0.000	0.986	0.014
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.014	0.986	0.000
M24.1 Other articular cartilage disorders	0.014	0.986	0.000
M25.49 Effusion of joint (Site unspecified)	0.014	0.986	0.000
M25.48 Effusion of joint (Other)	0.014	0.986	0.000
M25.44 Effusion of joint (Hand)	0.014	0.986	0.000
M25.41 Effusion of joint (Shoulder region)	0.014	0.986	0.000
M25.40 Effusion of joint (Multiple sites)	0.014	0.986	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.014	0.986	0.000
T36.0 Penicillins	0.000	0.986	0.014
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.014	0.986	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.014	0.986	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.014	0.986	0.000
M25.43 Effusion of joint (Forearm)	0.014	0.986	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.014	0.986	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.014	0.986	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.014	0.986	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.014	0.986	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.986	0.014
M24.6 Ankylosis of joint	0.014	0.986	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.014	0.986	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.014	0.986	0.000
L95.9 Vasculitis limited to skin, unspecified	0.014	0.986	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.986	0.014
L93.0 Discoid lupus erythematosus	0.014	0.986	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.013	0.986	0.000
M24.9 Joint derangement, unspecified	0.013	0.986	0.000
M25.42 Effusion of joint (Upper arm)	0.013	0.987	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.987	0.013
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.013	0.987	0.000
T36.9 Systemic antibiotic, unspecified	0.000	0.987	0.013
T36.8 Other systemic antibiotics	0.000	0.987	0.013
T36.7 Antifungal antibiotics, systemically used	0.000	0.987	0.013
T36.6 Rifamycins	0.000	0.987	0.013
T36.5 Aminoglycosides	0.000	0.987	0.013
T36.4 Tetracyclines	0.000	0.987	0.013
T36.3 Macrolides	0.000	0.987	0.013
T36.2 Chloramphenicol group	0.000	0.987	0.013
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.987	0.013
M25.98 Joint disorder, unspecified (Other)	0.013	0.987	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.013	0.987	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.013	0.987	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.013	0.987	0.000
M31.6 Other giant cell arteritis	0.013	0.987	0.000
T45.2 Vitamins, not elsewhere classified	0.000	0.987	0.013
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.987	0.013
T45.8 Other primarily systemic and haematological agents	0.000	0.987	0.013
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.987	0.013
T45.6 Fibrinolysis-affecting drugs	0.000	0.987	0.013
T45.4 Iron and its compounds	0.000	0.987	0.013
T45.3 Enzymes, not elsewhere classified	0.000	0.987	0.013
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.013	0.987	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.013	0.987	0.000
M21.2 Flexion deformity	0.013	0.987	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.013	0.987	0.000
M30.0 Polyarteritis nodosa	0.013	0.987	0.000
M31.8 Other specified necrotising vasculopathies	0.013	0.987	0.000
M31.7 Microscopic polyangiitis	0.013	0.987	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.013	0.987	0.000
M31.2 Lethal midline granuloma	0.013	0.987	0.000
M31.1 Thrombotic microangiopathy	0.013	0.987	0.000
M31.0 Hypersensitivity angiitis	0.013	0.987	0.000
M21.1 Varus deformity, not elsewhere classified	0.013	0.987	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.013	0.987	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.987	0.013
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.987	0.013
T37.5 Antiviral drugs	0.000	0.987	0.013
T37.4 Anthelminthics	0.000	0.987	0.013
T37.3 Other antiprotozoal drugs	0.000	0.987	0.013
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.987	0.013
T37.1 Antimycobacterial drugs	0.000	0.987	0.013
T37.0 Sulphonamides	0.000	0.987	0.013
T41.5 Therapeutic gases	0.000	0.987	0.013
T41.4 Anaesthetic, unspecified	0.000	0.987	0.013
T41.3 Local anaesthetics	0.000	0.987	0.013
T41.2 Other and unspecified general anaesthetics	0.000	0.987	0.013
T41.1 Intravenous anaesthetics	0.000	0.987	0.013
T41.0 Inhaled anaesthetics	0.000	0.987	0.013
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.987	0.013
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.987	0.013
T48.5 Anti-common-cold drugs	0.000	0.987	0.013
T48.4 Expectorants	0.000	0.987	0.013
T48.3 Antitussives	0.000	0.987	0.013
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.987	0.013
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.987	0.013
T48.0 Oxytocic drugs	0.000	0.987	0.013
T49.9 Topical agent, unspecified	0.000	0.987	0.013
T49.8 Other topical agents	0.000	0.987	0.013
T49.7 Dental drugs, topically applied	0.000	0.987	0.013
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.987	0.013
T49.5 Ophthalmological drugs and preparations	0.000	0.987	0.013
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.987	0.013
T49.3 Emollients, demulcents and protectants	0.000	0.987	0.013
T49.2 Local astringents and local detergents	0.000	0.987	0.013
T49.1 Antipruritics	0.000	0.987	0.013
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.987	0.013
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.013	0.987	0.000
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris	0.013	0.987	0.000
M22.10 Recurrent subluxation of patella, unspecified knee	0.012	0.987	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.012	0.987	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.012	0.987	0.000
M30.2 Juvenile polyarteritis	0.012	0.987	0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.012	0.987	0.000
L87 Transepidermal elimination disorders	0.012	0.987	0.000
L86 Keratoderma in diseases classified elsewhere	0.012	0.987	0.000
M25.94 Joint disorder, unspecified (Hand)	0.012	0.988	0.000
M24.2 Disorder of ligament	0.012	0.988	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.012	0.988	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.012	0.988	0.000
M36.3 Arthropathy in other blood disorders	0.012	0.988	0.000
M36.2 Haemophilic arthropathy	0.012	0.988	0.000
M36.1 Arthropathy in neoplastic disease	0.012	0.988	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.012	0.988	0.000
T39.1 4-Aminophenol derivatives	0.000	0.988	0.012
L88 Pyoderma gangrenosum	0.012	0.988	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.988	0.012
T50.8 Diagnostic agents	0.000	0.988	0.012
T50.7 Analeptics and opioid receptor antagonists	0.000	0.988	0.012
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.988	0.012
T50.5 Appetite depressants	0.000	0.988	0.012
T50.4 Drugs affecting uric acid metabolism	0.000	0.988	0.012
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.988	0.012
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.988	0.012
T50.1 Loop [high-ceiling] diuretics	0.000	0.988	0.012
T50.0 Mineralocorticoids and their antagonists	0.000	0.988	0.012
M25.45 Effusion of joint (Pelvic region and thigh)	0.012	0.988	0.000
L95.8 Other vasculitis limited to skin	0.012	0.988	0.000
M25.19 Fistula of joint (Site unspecified)	0.012	0.988	0.000
M25.18 Fistula of joint (Other)	0.012	0.988	0.000
M25.17 Fistula of joint (Ankle and foot)	0.012	0.988	0.000
M25.16 Fistula of joint (Lower leg)	0.012	0.988	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.012	0.988	0.000
M25.14 Fistula of joint (Hand)	0.012	0.988	0.000
M25.13 Fistula of joint (Forearm)	0.012	0.988	0.000
M25.12 Fistula of joint (Upper arm)	0.012	0.988	0.000
M25.11 Fistula of joint (Shoulder region)	0.012	0.988	0.000
M25.10 Fistula of joint (Multiple sites)	0.012	0.988	0.000
M25.29 Flail joint (Site unspecified)	0.012	0.988	0.000
M25.28 Flail joint (Other)	0.012	0.988	0.000
M25.27 Flail joint (Ankle and foot)	0.012	0.988	0.000
M25.26 Flail joint (Lower leg)	0.012	0.988	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.012	0.988	0.000
M25.24 Flail joint (Hand)	0.012	0.988	0.000
M25.23 Flail joint (Forearm)	0.012	0.988	0.000
M25.22 Flail joint (Upper arm)	0.012	0.988	0.000
M25.21 Flail joint (Shoulder region)	0.012	0.988	0.000
M25.20 Flail joint (Multiple sites)	0.012	0.988	0.000
G57 Mononeuropathies of lower limb	0.012	0.988	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.012	0.988	0.000
M32.8 Other forms of systemic lupus erythematosus	0.012	0.988	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.012	0.988	0.000
T45.5 Anticoagulants	0.000	0.988	0.012
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.012	0.988	0.000
G57.8 Other mononeuropathies of lower limb	0.012	0.988	0.000
M21.26 Flexion deformity (Lower leg)	0.012	0.988	0.000
M24.57 Contracture of joint (Ankle and foot)	0.012	0.988	0.000
M25.31 Other instability of joint (Shoulder region)	0.012	0.988	0.000
L94 Other localised connective tissue disorders	0.012	0.988	0.000
L85.3 Xerosis cutis	0.012	0.988	0.000
L85.2 Keratosis punctata (palmaris et plantaris)	0.012	0.988	0.000
L85.0 Acquired ichthyosis	0.012	0.988	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.988	0.012
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.988	0.012
T46.7 Peripheral vasodilators	0.000	0.988	0.012
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.988	0.012
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.988	0.012
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.988	0.012
L97 Ulcer of lower limb, not elsewhere classified	0.012	0.988	0.000
G58.9 Mononeuropathy, unspecified	0.012	0.988	0.000
M25.09 Haemarthrosis (Site unspecified)	0.011	0.988	0.000
M25.08 Haemarthrosis (Other)	0.011	0.988	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.011	0.988	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.011	0.988	0.000
M25.04 Haemarthrosis (Hand)	0.011	0.988	0.000
M25.03 Haemarthrosis (Forearm)	0.011	0.988	0.000
M25.02 Haemarthrosis (Upper arm)	0.011	0.988	0.000
M25.01 Haemarthrosis (Shoulder region)	0.011	0.988	0.000
M25.00 Haemarthrosis (Multiple sites)	0.011	0.988	0.000
M24.79 Protrusio acetabuli-Site unspec	0.011	0.988	0.000
M24.78 Protrusio acetabuli-Other	0.011	0.988	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.011	0.988	0.000
M24.76 Protrusio acetabuli-Lower leg	0.011	0.988	0.000
M24.74 Protrusio acetabuli-Hand	0.011	0.988	0.000
M24.73 Protrusio acetabuli-Forearm	0.011	0.988	0.000
M24.72 Protrusio acetabuli-Upper arm	0.011	0.988	0.000
M24.71 Protrusio acetabuli-Shldr region	0.011	0.988	0.000
M24.70 Protrusio acetabuli-Mult sites	0.011	0.988	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.011	0.988	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.011	0.988	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.011	0.988	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.011	0.988	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.011	0.988	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.011	0.988	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.011	0.988	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.011	0.988	0.000
M25.8 Other specified joint disorders	0.011	0.988	0.000
L81 Other disorders of pigmentation	0.012	0.988	0.000
M24.59 Contracture of joint (Site unspecified)	0.011	0.988	0.000
M24.58 Contracture of joint (Other)	0.011	0.988	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.011	0.988	0.000
M24.53 Contracture of joint (Forearm)	0.011	0.988	0.000
M24.52 Contracture of joint (Upper arm)	0.011	0.988	0.000
M24.50 Contracture of joint (Multiple sites)	0.011	0.988	0.000
M25.72 Osteophyte (Upper arm)	0.011	0.988	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.989	0.011
M25.36 Other instability of joint (Lower leg)	0.011	0.989	0.000
G58 Other mononeuropathies	0.011	0.989	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.989	0.011
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.011	0.989	0.000
M21.9 Acquired deformity of limb, unspecified	0.011	0.989	0.000
M21.8 Other specified acquired deformities of limbs	0.011	0.989	0.000
M21.7 Unequal limb length (acquired)	0.011	0.989	0.000
L95.1 Erythema elevatum diutinum	0.011	0.989	0.000
L95.0 Livedoid vasculitis	0.011	0.989	0.000
M21.6 Other acquired deformities of ankle and foot	0.011	0.989	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.011	0.989	0.000
M24.66 Ankylosis of joint (Lower leg)	0.011	0.989	0.000
L93.2 Other local lupus erythematosus	0.011	0.989	0.000
L93.1 Subacute cutaneous lupus erythematosus	0.011	0.989	0.000
M33.9 Dermatopolymyositis, unspecified	0.011	0.989	0.000
M33.0 Juvenile dermatomyositis	0.011	0.989	0.000
M24.24 Disorder of ligament (Hand)	0.011	0.989	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.011	0.989	0.000
L98.5 Mucinosis of skin	0.011	0.989	0.000
M33.1 Other dermatomyositis	0.011	0.989	0.000
M25.06 Haemarthrosis (Lower leg)	0.011	0.989	0.000
M25.39 Other instability of joint (Site unspecified)	0.011	0.989	0.000
M25.38 Other instability of joint (Other)	0.011	0.989	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.011	0.989	0.000
M25.33 Other instability of joint (Forearm)	0.011	0.989	0.000
M25.32 Other instability of joint (Upper arm)	0.011	0.989	0.000
M25.30 Other instability of joint (Multiple sites)	0.011	0.989	0.000
L98.7 Excessive and redundant skin and subcutaneous tissue	0.011	0.989	0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue	0.011	0.989	0.000
L98.3 Eosinophilic cellulitis [Wells]	0.011	0.989	0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]	0.011	0.989	0.000
L98.1 Factitial dermatitis	0.011	0.989	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.011	0.989	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.011	0.989	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.011	0.989	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.011	0.989	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.011	0.989	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.011	0.989	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.011	0.989	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.011	0.989	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.011	0.989	0.000
M21.4 Flat foot [pes planus] (acquired)	0.011	0.989	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.011	0.989	0.000
T38.9 Other and unspecified hormone antagonists	0.000	0.989	0.010
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.989	0.010
T38.7 Androgens and anabolic congeners	0.000	0.989	0.010
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.989	0.010
T38.5 Other oestrogens and progestogens	0.000	0.989	0.010
T38.4 Oral contraceptives	0.000	0.989	0.010
T38.2 Antithyroid drugs	0.000	0.989	0.010
T38.0 Glucocorticoids and synthetic analogues	0.000	0.989	0.010
M20.0 Deformity of finger(s)	0.011	0.989	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.010	0.989	0.000
M24.18 Other articular cartilage disorders (Other)	0.010	0.989	0.000
M24.14 Other articular cartilage disorders (Hand)	0.010	0.989	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.010	0.989	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.010	0.989	0.000
G57.1 Meralgia paraesthetica	0.010	0.990	0.000
G58.8 Other specified mononeuropathies	0.010	0.990	0.000
M24.56 Contracture of joint (Lower leg)	0.010	0.990	0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.010	0.990	0.000
T38.1 Thyroid hormones and substitutes	0.000	0.990	0.010
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.990	0.010
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.990	0.010
T47.7 Emetics	0.000	0.990	0.010
T47.6 Antidiarrhoeal drugs	0.000	0.990	0.010
T47.5 Digestants	0.000	0.990	0.010
T47.3 Saline and osmotic laxatives	0.000	0.990	0.010
T47.2 Stimulant laxatives	0.000	0.990	0.010
T47.0 Histamine H(2)-receptor antagonists	0.000	0.990	0.010
M24.69 Ankylosis of joint (Site unspecified)	0.010	0.990	0.000
M24.68 Ankylosis of joint (Other)	0.010	0.990	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.010	0.990	0.000
M24.64 Ankylosis of joint (Hand)	0.010	0.990	0.000
M24.63 Ankylosis of joint (Forearm)	0.010	0.990	0.000
M24.62 Ankylosis of joint (Upper arm)	0.010	0.990	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.010	0.990	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.010	0.990	0.000
G57.0 Lesion of sciatic nerve	0.010	0.990	0.000
M21.0 Valgus deformity, not elsewhere classified	0.010	0.990	0.000
T46.1 Calcium-channel blockers	0.000	0.990	0.010
G57.9 Mononeuropathy of lower limb, unspecified	0.010	0.990	0.000
N61 Inflammatory disorders of breast	0.010	0.990	0.000
M21.24 Flexion deformity (Hand)	0.010	0.990	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.010	0.990	0.000
M24.98 Joint derangement, unspecified (Other)	0.010	0.990	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.010	0.990	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.010	0.990	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.010	0.990	0.000
M24.94 Joint derangement, unspecified (Hand)	0.010	0.990	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.010	0.990	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.010	0.990	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.010	0.990	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.010	0.990	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.010	0.990	0.000
G50 Disorders of trigeminal nerve	0.010	0.990	0.000
M25.34 Other instability of joint (Hand)	0.010	0.990	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.010	0.990	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.010	0.990	0.000
M24.54 Contracture of joint (Hand)	0.010	0.990	0.000
L84 Corns and callosities	0.010	0.990	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.010	0.990	0.000
M21.29 Flexion deformity (Site unspecified)	0.009	0.990	0.000
M21.28 Flexion deformity (Other)	0.009	0.990	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.009	0.990	0.000
M21.23 Flexion deformity (Forearm)	0.009	0.990	0.000
M21.22 Flexion deformity (Upper arm)	0.009	0.990	0.000
M21.21 Flexion deformity (Shoulder region)	0.009	0.990	0.000
M21.20 Flexion deformity (Multiple sites)	0.009	0.990	0.000
G57.5 Tarsal tunnel syndrome	0.010	0.990	0.000
G50.0 Trigeminal neuralgia	0.010	0.990	0.000
L94.8 Other specified localised connective tissue disorders	0.009	0.990	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.009	0.991	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.009	0.991	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.009	0.991	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.009	0.991	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.009	0.991	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.009	0.991	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.009	0.991	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.009	0.991	0.000
G57.6 Lesion of plantar nerve	0.009	0.991	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.009	0.991	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.009	0.991	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.991	0.009
M33.2 Polymyositis	0.009	0.991	0.000
M25.83 Other specified joint disorders (Forearm)	0.009	0.991	0.000
T40.2 Other opioids	0.000	0.991	0.009
L87.9 Transepidermal elimination disorder, unspecified	0.009	0.991	0.000
L87.8 Other transepidermal elimination disorders	0.009	0.991	0.000
L87.2 Elastosis perforans serpiginosa	0.009	0.991	0.000
L87.1 Reactive perforating collagenosis	0.009	0.991	0.000
L87.0 Keratosis follicularis et parafollicularis in cutem penetrans [Kyrle]	0.009	0.991	0.000
L99.8 Other specified disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.009	0.991	0.000
L99.0 Amyloidosis of skin	0.009	0.991	0.000
M24.29 Disorder of ligament (Site unspecified)	0.009	0.991	0.000
M24.28 Disorder of ligament (Other)	0.009	0.991	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.009	0.991	0.000
M24.22 Disorder of ligament (Upper arm)	0.009	0.991	0.000
M24.21 Disorder of ligament (Shoulder region)	0.009	0.991	0.000
M24.20 Disorder of ligament (Multiple sites)	0.009	0.991	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.991	0.009
T40.8 Lysergide [LSD]	0.000	0.991	0.009
T40.7 Cannabis (derivatives)	0.000	0.991	0.009
T40.5 Cocaine	0.000	0.991	0.009
T40.3 Methadone	0.000	0.991	0.009
T40.1 Heroin	0.000	0.991	0.009
T40.0 Opium	0.000	0.991	0.009
G58.7 Mononeuritis multiplex	0.009	0.991	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.991	0.009
M24.26 Disorder of ligament (Lower leg)	0.009	0.991	0.000
G57.4 Lesion of medial popliteal nerve	0.009	0.991	0.000
G57.2 Lesion of femoral nerve	0.009	0.991	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.000	0.991	0.009
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.009	0.991	0.000
L98.4 Chronic ulcer of skin, not elsewhere classified	0.009	0.991	0.000
G52 Disorders of other cranial nerves	0.009	0.991	0.000
L94.9 Localised connective tissue disorder, unspecified	0.009	0.991	0.000
L94.6 Ainhum	0.009	0.991	0.000
L94.5 Poikiloderma vasculare atrophicans	0.009	0.991	0.000
L94.4 Gottron's papules	0.009	0.991	0.000
L94.3 Sclerodactyly	0.009	0.991	0.000
L94.1 Linear scleroderma	0.009	0.991	0.000
T47.4 Other laxatives	0.000	0.991	0.008
M25.89 Other specified joint disorders (Site unspecified)	0.008	0.991	0.000
M25.82 Other specified joint disorders (Upper arm)	0.008	0.991	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.008	0.991	0.000
L81.7 Pigmented purpuric dermatosis	0.008	0.991	0.000
L81.6 Other disorders of diminished melanin formation	0.008	0.991	0.000
L81.5 Leukoderma, not elsewhere classified	0.008	0.991	0.000
L81.3 Cafe au lait spots	0.008	0.991	0.000
L81.2 Freckles	0.008	0.991	0.000
L81.1 Chloasma	0.008	0.991	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations