TreeWAS – Variant ID: rs3924223

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
F05.9 Delirium, unspecified	0.000	0.971	0.029
C18.2 Ascending colon	0.021	0.979	0.000
L28.0 Lichen simplex chronicus	0.020	0.980	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.000	0.982	0.018
F05.1 Delirium superimposed on dementia	0.000	0.985	0.015
F05.8 Other delirium	0.000	0.985	0.015
F05.0 Delirium not superimposed on dementia, so described	0.000	0.987	0.013
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.013	0.987	0.000
S22.30 Fracture of rib (closed)	0.000	0.991	0.009
H66.9 Otitis media, unspecified	0.008	0.992	0.000
L28 Lichen simplex chronicus and prurigo	0.007	0.993	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.993	0.007
N99.4 Postprocedural pelvic peritoneal adhesions	0.007	0.993	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.007	0.993	0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.000	0.994	0.006
S92.20 Fracture of other tarsal bone(s) (closed)	0.006	0.994	0.000
O41.0 Oligohydramnios	0.000	0.994	0.006
H66 Suppurative and unspecified otitis media	0.006	0.994	0.000
R73.9 Hyperglycaemia, unspecified	0.000	0.994	0.006
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.994	0.006
H66.3 Other chronic suppurative otitis media	0.006	0.994	0.000
R14 Flatulence and related conditions	0.000	0.994	0.006
L28.2 Other prurigo	0.005	0.994	0.000
F45.8 Other somatoform disorders	0.005	0.995	0.000
F43.0 Acute stress reaction	0.000	0.995	0.005
N76.0 Acute vaginitis	0.005	0.995	0.000
S92.2 Fracture of other tarsal bone(s)	0.005	0.995	0.000
N64.9 Disorder of breast, unspecified	0.000	0.995	0.005
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.995	0.005
H66.2 Chronic atticoantral suppurative otitis media	0.005	0.995	0.000
L28.1 Prurigo nodularis	0.005	0.995	0.000
L93.0 Discoid lupus erythematosus	0.005	0.995	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.995	0.005
O41 Other disorders of amniotic fluid and membranes	0.000	0.995	0.005
S22.3 Fracture of rib	0.000	0.995	0.005
H66.0 Acute suppurative otitis media	0.005	0.995	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.000	0.995	0.005
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.996	0.004
H66.1 Chronic tubotympanic suppurative otitis media	0.004	0.996	0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.004	0.996	0.000
Z50.2 Alcohol rehabilitation	0.000	0.996	0.004
O34.1 Maternal care for tumour of corpus uteri	0.000	0.996	0.004
N48.1 Balanoposthitis	0.000	0.996	0.004
H66.4 Suppurative otitis media, unspecified	0.004	0.996	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.000	0.996	0.004
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.996	0.004
O41.1 Infection of amniotic sac and membranes	0.000	0.996	0.004
I37.1 Pulmonary valve insufficiency	0.000	0.996	0.004
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.996	0.004
S92 Fracture of foot, except ankle	0.004	0.996	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.000	0.996	0.004
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.996	0.004
O35 Maternal care for known or suspected foetal abnormality and damage	0.000	0.996	0.004
S92.21 Fracture of other tarsal bone(s) (open)	0.004	0.996	0.000
S92.3 Fracture of metatarsal bone	0.004	0.996	0.000
S02.20 Fracture of nasal bones (closed)	0.004	0.996	0.000
S92.30 Fracture of metatarsal bone (closed)	0.004	0.996	0.000
C79 Secondary malignant neoplasm of other sites	0.000	0.996	0.004
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.000	0.996	0.004
S92.0 Fracture of calcaneus	0.004	0.996	0.000
S22.31 Fracture of rib (open)	0.000	0.996	0.003
S92.00 Fracture of calcaneus (closed)	0.004	0.996	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.000	0.996	0.004
O34.4 Maternal care for other abnormalities of cervix	0.000	0.996	0.004
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.000	0.996	0.003
M84.4 Pathological fracture, not elsewhere classified	0.000	0.996	0.003
Y79.2 Prosthetic and other implants, materials and accessory devices	0.003	0.997	0.000
N02.9 Unspecified	0.003	0.997	0.000
C18.7 Sigmoid colon	0.003	0.997	0.000
C79.2 Secondary malignant neoplasm of skin	0.000	0.997	0.003
C18 Malignant neoplasm of colon	0.003	0.997	0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.000	0.997	0.003
S92.9 Fracture of foot, unspecified	0.003	0.997	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.997	0.003
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.997	0.003
O34 Maternal care for known or suspected abnormality of pelvic organs	0.000	0.997	0.003
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.997	0.003
N30.1 Interstitial cystitis (chronic)	0.000	0.997	0.003
S92.4 Fracture of great toe	0.003	0.997	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.997	0.003
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.997	0.003
Y84.8 Other medical procedures	0.000	0.997	0.003
M84 Disorders of continuity of bone	0.000	0.997	0.003
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.997	0.003
C18.8 Overlapping lesion of colon	0.003	0.997	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.000	0.997	0.003
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.997	0.003
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.000	0.997	0.003
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.000	0.997	0.003
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.000	0.997	0.003
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.000	0.997	0.003
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.000	0.997	0.003
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.000	0.997	0.003
F00-F09 Organic, including symptomatic, mental disorders	0.000	0.997	0.003
S92.31 Fracture of metatarsal bone (open)	0.003	0.997	0.000
N48.8 Other specified disorders of penis	0.000	0.997	0.003
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.003	0.997	0.000
S92.7 Multiple fractures of foot	0.003	0.997	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.997	0.003
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.997	0.003
S92.01 Fracture of calcaneus (open)	0.003	0.997	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.003	0.997	0.000
C18.5 Splenic flexure	0.003	0.997	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.997	0.003
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.997	0.003
H61.3 Acquired stenosis of external ear canal	0.000	0.997	0.003
F45 Somatoform disorders	0.003	0.997	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.000	0.997	0.003
H72 Perforation of tympanic membrane	0.003	0.997	0.000
S92.5 Fracture of other toe	0.003	0.997	0.000
S93.0 Dislocation of ankle joint	0.003	0.997	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.000	0.997	0.003
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.000	0.997	0.003
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.000	0.997	0.003
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.000	0.997	0.003
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.000	0.997	0.003
S92.90 Fracture of foot, unspecified (closed)	0.003	0.997	0.000
K56.1 Intussusception	0.000	0.997	0.003
H65-H75 Diseases of middle ear and mastoid	0.003	0.997	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.000	0.997	0.003
S92.41 Fracture of great toe (open)	0.003	0.997	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.000	0.997	0.003
O34.7 Maternal care for abnormality of vulva and perineum	0.000	0.997	0.003
O34.5 Maternal care for other abnormalities of gravid uterus	0.000	0.997	0.003
N81.3 Complete uterovaginal prolapse	0.000	0.997	0.003
K62.3 Rectal prolapse	0.000	0.997	0.003
M84.8 Other disorders of continuity of bone	0.000	0.997	0.003
N76.5 Ulceration of vagina	0.003	0.997	0.000
Z00.0 General medical examination	0.000	0.997	0.003
F02 Dementia in other diseases classified elsewhere	0.000	0.997	0.003
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.000	0.997	0.003
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.000	0.997	0.002
S92.91 Fracture of foot, unspecified (open)	0.002	0.997	0.000
R94.3 Abnormal results of cardiovascular function studies	0.000	0.997	0.003
S92.1 Fracture of talus	0.002	0.997	0.000
H65.4 Other chronic nonsuppurative otitis media	0.003	0.997	0.000
H71 Cholesteatoma of middle ear	0.003	0.997	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.000	0.997	0.002
O34.6 Maternal care for abnormality of vagina	0.000	0.997	0.002
F45.9 Somatoform disorder, unspecified	0.002	0.997	0.000
H72.2 Other marginal perforations of tympanic membrane	0.003	0.997	0.000
N76.8 Other specified inflammation of vagina and vulva	0.003	0.997	0.000
S02.21 Fracture of nasal bones (open)	0.002	0.997	0.000
M84.9 Disorder of continuity of bone, unspecified	0.000	0.997	0.002
N76 Other inflammation of vagina and vulva	0.003	0.997	0.000
O34.3 Maternal care for cervical incompetence	0.000	0.997	0.002
S92.40 Fracture of great toe (closed)	0.002	0.998	0.000
I69.3 Sequelae of cerebral infarction	0.000	0.998	0.002
O34.0 Maternal care for congenital malformation of uterus	0.000	0.998	0.002
H73 Other disorders of tympanic membrane	0.002	0.998	0.000
R73 Elevated blood glucose level	0.000	0.998	0.002
H72.1 Attic perforation of tympanic membrane	0.002	0.998	0.000
S02.2 Fracture of nasal bones	0.002	0.998	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.000	0.998	0.002
F02.3 Dementia in Parkinson's disease	0.000	0.998	0.002
M84.3 Stress fracture, not elsewhere classified	0.000	0.998	0.002
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.000	0.998	0.002
S92.71 Multiple fractures of foot (open)	0.002	0.998	0.000
H61.9 Disorder of external ear, unspecified	0.000	0.998	0.002
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.000	0.998	0.002
M84.2 Delayed union of fracture	0.000	0.998	0.002
N76.1 Subacute and chronic vaginitis	0.002	0.998	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.000	0.998	0.002
C38.4 Pleura	0.002	0.998	0.000
H61.0 Perichondritis of external ear	0.000	0.998	0.002
F45.4 Persistent somatoform pain disorder	0.002	0.998	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
S92.51 Fracture of other toe (open)	0.002	0.998	0.000
F45.3 Somatoform autonomic dysfunction	0.002	0.998	0.000
F45.1 Undifferentiated somatoform disorder	0.002	0.998	0.000
M84.02 Malunion of fracture (Upper arm)	0.000	0.998	0.002
F45.0 Somatisation disorder	0.002	0.998	0.000
M84.0 Malunion of fracture	0.000	0.998	0.002
F09 Unspecified organic or symptomatic mental disorder	0.000	0.998	0.002
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.002	0.998	0.000
H72.0 Central perforation of tympanic membrane	0.002	0.998	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.002	0.998	0.000
N48.0 Leukoplakia of penis	0.000	0.998	0.002
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.002	0.998	0.000
H67 Otitis media in diseases classified elsewhere	0.002	0.998	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.998	0.000
Y79 Orthopaedic devices associated with adverse incidents	0.002	0.998	0.000
F45.2 Hypochondriacal disorder	0.002	0.998	0.000
H68 Eustachian salpingitis and obstruction	0.002	0.998	0.000
H65 Nonsuppurative otitis media	0.002	0.998	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.998	0.002
M84.89 Other disorders of continuity of bone (Site unspecified)	0.000	0.998	0.002
M84.88 Other disorders of continuity of bone (Other)	0.000	0.998	0.002
M84.86 Other disorders of continuity of bone (Lower leg)	0.000	0.998	0.002
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.000	0.998	0.002
M84.84 Other disorders of continuity of bone (Hand)	0.000	0.998	0.002
M84.82 Other disorders of continuity of bone (Upper arm)	0.000	0.998	0.002
M84.81 Other disorders of continuity of bone (Shoulder region)	0.000	0.998	0.002
M84.80 Other disorders of continuity of bone (Multiple sites)	0.000	0.998	0.002
S92.70 Multiple fractures of foot (closed)	0.002	0.998	0.000
F02.0 Dementia in Pick's disease	0.000	0.998	0.002
I37 Pulmonary valve disorders	0.000	0.998	0.002
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.000	0.998	0.002
F02.2 Dementia in Huntington's disease	0.000	0.998	0.002
F02.1 Dementia in Creutzfeldt-Jakob disease	0.000	0.998	0.002
H73.8 Other specified disorders of tympanic membrane	0.002	0.998	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.998	0.002
S92.11 Fracture of talus (open)	0.002	0.998	0.000
H73.0 Acute myringitis	0.002	0.998	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.002	0.998	0.000
C18.1 Appendix	0.002	0.998	0.000
H60.9 Otitis externa, unspecified	0.002	0.998	0.000
N76.3 Subacute and chronic vulvitis	0.002	0.998	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.000	0.998	0.002
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.000	0.998	0.002
C79.6 Secondary malignant neoplasm of ovary	0.000	0.998	0.002
F02.8 Dementia in other specified diseases classified elsewhere	0.000	0.998	0.002
F07.0 Organic personality disorder	0.000	0.998	0.002
I37.0 Pulmonary valve stenosis	0.000	0.998	0.002
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.000	0.998	0.002
M84.98 Disorder of continuity of bone, unspecified (Other)	0.000	0.998	0.002
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.000	0.998	0.002
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.000	0.998	0.002
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.000	0.998	0.002
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.000	0.998	0.002
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.000	0.998	0.002
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.000	0.998	0.002
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.000	0.998	0.002
C18.0 Caecum	0.002	0.998	0.000
N48 Other disorders of penis	0.000	0.998	0.002
F07.2 Postconcussional syndrome	0.000	0.998	0.002
M84.05 Malunion of fracture (Pelvic region and thigh)	0.000	0.998	0.002
C18.9 Colon, unspecified	0.002	0.998	0.000
S93.1 Dislocation of toe(s)	0.002	0.998	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.998	0.002
M84.08 Malunion of fracture (Other)	0.000	0.998	0.002
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.000	0.998	0.002
M84.38 Stress fracture, not elsewhere classified (Other)	0.000	0.998	0.002
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.000	0.998	0.002
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.998	0.002
M84.34 Stress fracture, not elsewhere classified (Hand)	0.000	0.998	0.002
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.000	0.998	0.002
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.000	0.998	0.002
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.000	0.998	0.002
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.000	0.998	0.002
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.000	0.998	0.002
H65.3 Chronic mucoid otitis media	0.002	0.998	0.000
N02 Recurrent and persistent haematuria	0.002	0.998	0.000
M84.01 Malunion of fracture (Shoulder region)	0.000	0.998	0.002
M84.26 Delayed union of fracture (Lower leg)	0.000	0.998	0.002
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.000	0.998	0.002
F07.1 Postencephalitic syndrome	0.000	0.998	0.002
S93.6 Sprain and strain of other and unspecified parts of foot	0.002	0.998	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.998	0.002
M84.29 Delayed union of fracture (Site unspecified)	0.000	0.998	0.002
M84.28 Delayed union of fracture (Other)	0.000	0.998	0.002
M84.27 Delayed union of fracture (Ankle and foot)	0.000	0.998	0.002
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.000	0.998	0.002
M84.24 Delayed union of fracture (Hand)	0.000	0.998	0.002
M84.23 Delayed union of fracture (Forearm)	0.000	0.998	0.002
M84.22 Delayed union of fracture (Upper arm)	0.000	0.998	0.002
M84.20 Delayed union of fracture (Multiple sites)	0.000	0.998	0.002
H73.1 Chronic myringitis	0.002	0.998	0.000
C18.4 Transverse colon	0.002	0.998	0.000
H60.1 Cellulitis of external ear	0.002	0.998	0.000
H60 Otitis externa	0.002	0.998	0.000
C32.9 Larynx, unspecified	0.002	0.998	0.000
M10.93 Gout, unspecified (Forearm)	0.000	0.998	0.002
M84.09 Malunion of fracture (Site unspecified)	0.000	0.998	0.002
M84.00 Malunion of fracture (Multiple sites)	0.000	0.998	0.002
H73.9 Disorder of tympanic membrane, unspecified	0.002	0.998	0.000
I72.4 Aneurysm of artery of lower extremity	0.000	0.998	0.002
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
H61 Other disorders of external ear	0.000	0.998	0.002
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
S92.50 Fracture of other toe (closed)	0.002	0.998	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.002	0.998	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.002	0.998	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.002	0.998	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.002	0.998	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
S93.4 Sprain and strain of ankle	0.002	0.998	0.000
S93.5 Sprain and strain of toe(s)	0.002	0.998	0.000
Y79.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y79.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
Y79.0 Diagnostic and monitoring devices	0.002	0.998	0.000
F01 Vascular dementia	0.000	0.998	0.002
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.998	0.002
I46.9 Cardiac arrest, unspecified	0.002	0.998	0.000
S90-S99 Injuries to the ankle and foot	0.002	0.998	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.002	0.998	0.000
M84.04 Malunion of fracture (Hand)	0.000	0.998	0.002
H68.0 Eustachian salpingitis	0.002	0.998	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.002	0.998	0.000
Y79.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
Z90.5 Acquired absence of kidney	0.002	0.998	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.000	0.998	0.002
F06.5 Organic dissociative disorder	0.000	0.998	0.002
F06.4 Organic anxiety disorder	0.000	0.998	0.002
F06.3 Organic mood [affective] disorders	0.000	0.998	0.002
F06.1 Organic catatonic disorder	0.000	0.998	0.002
F06.0 Organic hallucinosis	0.000	0.998	0.002
H65.1 Other acute nonsuppurative otitis media	0.002	0.998	0.000
I37.9 Pulmonary valve disorder, unspecified	0.000	0.998	0.002
I37.8 Other pulmonary valve disorders	0.000	0.998	0.002
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.998	0.002
N02.2 Diffuse membranous glomerulonephritis	0.002	0.998	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.998	0.002
M62.66 Muscle strain (Lower leg)	0.002	0.998	0.000
E55.9 Vitamin D deficiency, unspecified	0.002	0.998	0.000
N48.5 Ulcer of penis	0.000	0.998	0.002
R73.0 Abnormal glucose tolerance test	0.000	0.998	0.002
M84.21 Delayed union of fracture (Shoulder region)	0.000	0.998	0.002
H60.2 Malignant otitis externa	0.002	0.998	0.000
H60.0 Abscess of external ear	0.002	0.998	0.000
H68.1 Obstruction of Eustachian tube	0.002	0.998	0.000
N02.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.998	0.000
O36.9 Maternal care for foetal problem, unspecified	0.002	0.998	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.998	0.002
H60.8 Other otitis externa	0.002	0.998	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.002	0.998	0.000
F00 Dementia in Alzheimer's disease	0.000	0.998	0.002
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.998	0.002
F06.2 Organic delusional [schizophrenia-like] disorder	0.000	0.998	0.002
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.000	0.998	0.001
H60.5 Acute otitis externa, non-infective	0.002	0.998	0.000
I67.1 Cerebral aneurysm, nonruptured	0.000	0.998	0.002
I72.3 Aneurysm of iliac artery	0.000	0.998	0.002
S97 Crushing injury of ankle and foot	0.002	0.998	0.000
Z35 Supervision of high-risk pregnancy	0.002	0.998	0.000
D58.0 Hereditary spherocytosis	0.002	0.998	0.000
H72.8 Other perforations of tympanic membrane	0.002	0.998	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.998	0.002
F43 Reaction to severe stress, and adjustment disorders	0.000	0.998	0.002
S93.2 Rupture of ligaments at ankle and foot level	0.002	0.998	0.000
L93 Lupus erythematosus	0.002	0.998	0.000
M70.46 Prepatellar bursitis-Lower Leg	0.002	0.998	0.000
M84.06 Malunion of fracture (Lower leg)	0.000	0.998	0.002
E53.9 Vitamin B deficiency, unspecified	0.002	0.998	0.000
N02.7 Diffuse crescentic glomerulonephritis	0.002	0.998	0.000
N02.6 Dense deposit disease	0.002	0.998	0.000
N02.5 Diffuse mesangiocapillary glomerulonephritis	0.002	0.998	0.000
N02.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.998	0.000
N02.1 Focal and segmental glomerular lesions	0.002	0.998	0.000
S36.00 Injury of spleen (without open wound into cavity)	0.000	0.998	0.002
N02.8 Other	0.002	0.998	0.000
F03 Unspecified dementia	0.000	0.998	0.002
S98 Traumatic amputation of ankle and foot	0.002	0.998	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.998	0.002
H70 Mastoiditis and related conditions	0.002	0.998	0.000
N02.0 Minor glomerular abnormality	0.002	0.998	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.998	0.002
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.002	0.998	0.000
M62.65 Muscle strain (Pelvic region and thigh)	0.002	0.998	0.000
S92.10 Fracture of talus (closed)	0.001	0.998	0.000
E53.8 Deficiency of other specified B group vitamins	0.002	0.998	0.000
M10.9 Gout, unspecified	0.000	0.998	0.002
F01.1 Multi-infarct dementia	0.000	0.998	0.001
O04.4 Incomplete, without complication	0.000	0.998	0.002
S97.8 Crushing injury of other parts of ankle and foot	0.002	0.998	0.000
S97.1 Crushing injury of toe(s)	0.002	0.998	0.000
E53 Deficiency of other B group vitamins	0.002	0.998	0.000
H69 Other disorders of Eustachian tube	0.002	0.998	0.000
S93.40 Sprain of unspecified ligament of ankle	0.001	0.998	0.000
F01.8 Other vascular dementia	0.000	0.998	0.001
F01.3 Mixed cortical and subcortical vascular dementia	0.000	0.998	0.001
F01.2 Subcortical vascular dementia	0.000	0.998	0.001
F01.0 Vascular dementia of acute onset	0.000	0.998	0.001
F43.2 Adjustment disorders	0.000	0.998	0.002
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.998	0.002
N76.6 Ulceration of vulva	0.001	0.998	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.002	0.998	0.000
S95 Injury of blood vessels at ankle and foot level	0.002	0.998	0.000
S94 Injury of nerves at ankle and foot level	0.002	0.998	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.001	0.998	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.001	0.998	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.001	0.998	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.001	0.998	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.998	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.001	0.998	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.001	0.998	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.001	0.998	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.001	0.998	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.998	0.001
G61.8 Other inflammatory polyneuropathies	0.002	0.998	0.000
N48.3 Priapism	0.000	0.998	0.001
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.000	0.998	0.001
H01.8 Other specified inflammation of eyelid	0.002	0.998	0.000
H60.4 Cholesteatoma of external ear	0.001	0.998	0.000
H70.1 Chronic mastoiditis	0.001	0.998	0.000
S98.1 Traumatic amputation of one toe	0.001	0.998	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.998	0.001
F06.7 Mild cognitive disorder	0.000	0.998	0.002
S93.3 Dislocation of other and unspecified parts of foot	0.001	0.998	0.000
I69 Sequelae of cerebrovascular disease	0.000	0.998	0.002
C67.2 Lateral wall of bladder	0.000	0.998	0.002
D22.1 Melanocytic naevi of eyelid, including canthus	0.000	0.998	0.002
N48.2 Other inflammatory disorders of penis	0.000	0.998	0.002
O30.0 Twin pregnancy	0.000	0.998	0.002
E55 Vitamin D deficiency	0.002	0.998	0.000
C18.6 Descending colon	0.001	0.998	0.000
H60.3 Other infective otitis externa	0.001	0.998	0.000
Q43.8 Other specified congenital malformations of intestine	0.000	0.998	0.002
Q53.1 Undescended testicle, unilateral	0.000	0.998	0.002
S97.0 Crushing injury of ankle	0.001	0.998	0.000
Z35.7 Supervision of high-risk pregnancy due to social problems	0.001	0.998	0.000
Z35.6 Supervision of very young primigravida	0.001	0.998	0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.001	0.998	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
F43.8 Other reactions to severe stress	0.000	0.998	0.001
M62.6 Muscle strain	0.002	0.998	0.000
H65.0 Acute serous otitis media	0.001	0.998	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.002	0.998	0.000
I45.2 Bifascicular block	0.000	0.998	0.002
S98.4 Traumatic amputation of foot, level unspecified	0.001	0.998	0.000
S98.3 Traumatic amputation of other parts of foot	0.001	0.998	0.000
S98.2 Traumatic amputation of two or more toes	0.001	0.998	0.000
S98.0 Traumatic amputation of foot at ankle level	0.001	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.001	0.998	0.000
M70.22 Olecranon bursitis-Upper arm	0.001	0.998	0.000
F43.9 Reaction to severe stress, unspecified	0.000	0.998	0.001
H70.2 Petrositis	0.001	0.998	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.998	0.001
S96.8 Injury of other muscles and tendons at ankle and foot level	0.001	0.998	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.998	0.002
T02.40 Fractures involving multiple regions of both upper limbs (closed)	0.000	0.999	0.001
D58.9 Hereditary haemolytic anaemia, unspecified	0.001	0.999	0.000
G43.1 Migraine with aura [classical migraine]	0.000	0.999	0.001
H65.9 Nonsuppurative otitis media, unspecified	0.001	0.999	0.000
S22.1 Multiple fractures of thoracic spine	0.000	0.999	0.001
M80 Osteoporosis with pathological fracture	0.001	0.999	0.000
M10.98 Gout, unspecified (Other)	0.000	0.999	0.001
M10.96 Gout, unspecified (Lower leg)	0.000	0.999	0.001
M10.95 Gout, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
M10.91 Gout, unspecified (Shoulder region)	0.000	0.999	0.001
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.999	0.001
S82.00 Fracture of patella (closed)	0.001	0.999	0.000
D86.8 Sarcoidosis of other and combined sites	0.000	0.999	0.001
E53.1 Pyridoxine deficiency	0.001	0.999	0.000
E53.0 Riboflavin deficiency	0.001	0.999	0.000
H69.0 Patulous Eustachian tube	0.001	0.999	0.000
O02.0 Blighted ovum and nonhydatidiform mole	0.001	0.999	0.000
Q43.3 Congenital malformations of intestinal fixation	0.000	0.999	0.001
C38 Malignant neoplasm of heart, mediastinum and pleura	0.001	0.999	0.000
E63.9 Nutritional deficiency, unspecified	0.001	0.999	0.000
L93.1 Subacute cutaneous lupus erythematosus	0.001	0.999	0.000
N76.2 Acute vulvitis	0.001	0.999	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.001	0.999	0.000
S94.8 Injury of other nerves at ankle and foot level	0.001	0.999	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.001	0.999	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.001	0.999	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.001	0.999	0.000
S94.1 Injury of medial plantar nerve	0.001	0.999	0.000
S94.0 Injury of lateral plantar nerve	0.001	0.999	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.001	0.999	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.001	0.999	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.001	0.999	0.000
S95.2 Injury of dorsal vein of foot	0.001	0.999	0.000
S95.1 Injury of plantar artery of foot	0.001	0.999	0.000
S95.0 Injury of dorsal artery of foot	0.001	0.999	0.000
M62.68 Muscle strain (Other)	0.001	0.999	0.000
L93.2 Other local lupus erythematosus	0.001	0.999	0.000
Z35.8 Supervision of other high-risk pregnancies	0.001	0.999	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.000	0.999	0.001
M10.92 Gout, unspecified (Upper arm)	0.000	0.999	0.001
C18.3 Hepatic flexure	0.001	0.999	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.999	0.001
E55.0 Rickets, active	0.001	0.999	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.999	0.001
M80.8 Other osteoporosis with pathological fracture	0.001	0.999	0.000
O75.0 Maternal distress during labour and delivery	0.001	0.999	0.000
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.000	0.999	0.001
O40 Polyhydramnios	0.000	0.999	0.001
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.001	0.999	0.000
M67.47 Ganglion, ankle and foot	0.001	0.999	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
C38.3 Mediastinum, part unspecified	0.001	0.999	0.000
G91.8 Other hydrocephalus	0.000	0.999	0.001
S69.9 Unspecified injury of wrist and hand	0.001	0.999	0.000
S91.0 Open wound of ankle	0.001	0.999	0.000
M62.69 Muscle strain (Site unspecified)	0.001	0.999	0.000
M62.67 Muscle strain (Ankle and foot)	0.001	0.999	0.000
M62.64 Muscle strain (Hand)	0.001	0.999	0.000
M62.63 Muscle strain (Forearm)	0.001	0.999	0.000
M62.62 Muscle strain (Upper arm)	0.001	0.999	0.000
M62.61 Muscle strain (Shoulder region)	0.001	0.999	0.000
M62.60 Muscle strain (Multiple sites)	0.001	0.999	0.000
H70.0 Acute mastoiditis	0.001	0.999	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.001	0.999	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.001	0.999	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.001	0.999	0.000
Z98.1 Arthrodesis status	0.001	0.999	0.000
E63 Other nutritional deficiencies	0.001	0.999	0.000
S91 Open wound of ankle and foot	0.001	0.999	0.000
H70.8 Other mastoiditis and related conditions	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations