TreeWAS – Variant ID: rs404005

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C83.0 Small cell (diffuse)	0.010	0.990	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.010	0.990	0.000
C92 Myeloid leukaemia	0.009	0.991	0.000
C83.1 Small cleaved cell (diffuse)	0.009	0.991	0.000
C92.0 Acute myeloid leukaemia	0.009	0.991	0.000
D07.5 Prostate	0.000	0.991	0.009
G72.9 Myopathy, unspecified	0.000	0.992	0.008
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.008	0.992	0.000
C83.7 Burkitt's tumour	0.008	0.992	0.000
C92.7 Other myeloid leukaemia	0.008	0.992	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.008	0.992	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.008	0.992	0.000
C92.4 Acute promyelocytic leukaemia	0.007	0.992	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.007	0.993	0.000
C92.9 Myeloid leukaemia, unspecified	0.007	0.993	0.000
Z01.8 Other specified special examinations	0.000	0.993	0.007
C83.6 Undifferentiated (diffuse)	0.007	0.993	0.000
C83.4 Immunoblastic (diffuse)	0.007	0.993	0.000
C83.2 Mixed small and large cell (diffuse)	0.007	0.993	0.000
C92.1 Chronic myeloid leukaemia	0.007	0.993	0.000
C83.5 Lymphoblastic (diffuse)	0.007	0.993	0.000
C92.2 Subacute myeloid leukaemia	0.007	0.993	0.000
K22.4 Dyskinesia of oesophagus	0.007	0.993	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.007	0.993	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.007	0.993	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.007	0.993	0.000
C92.3 Myeloid sarcoma	0.007	0.993	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.007	0.993	0.000
C84.5 Other and unspecified T-cell lymphomas	0.006	0.993	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.007	0.993	0.000
C84.4 Peripheral T-cell lymphoma	0.006	0.993	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.006	0.994	0.000
C92.5 Acute myelomonocytic leukaemia	0.006	0.994	0.000
C91 Lymphoid leukaemia	0.006	0.994	0.000
C84.0 Mycosis fungoides	0.006	0.994	0.000
D50.8 Other iron deficiency anaemias	0.000	0.994	0.006
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.006	0.994	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.006	0.994	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.006	0.994	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.006	0.994	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.006	0.994	0.000
C84.3 Lymphoepithelioid lymphoma	0.006	0.994	0.000
C84.2 T-zone lymphoma	0.006	0.994	0.000
C84.1 Sezary's diease	0.006	0.994	0.000
T43.2 Other and unspecified antidepressants	0.006	0.994	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.006	0.994	0.000
C91.4 Hairy-cell leukaemia	0.006	0.994	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.006	0.994	0.000
C93 Monocytic leukaemia	0.006	0.994	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.006	0.994	0.000
G72 Other myopathies	0.000	0.994	0.006
C91.0 Acute lymphoblastic leukaemia	0.006	0.994	0.000
C94 Other leukaemias of specified cell type	0.006	0.994	0.000
C83.3 Large cell (diffuse)	0.006	0.994	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.006	0.994	0.000
T40.6 Other and unspecified narcotics	0.006	0.994	0.000
C86 Other specified types of T/NK-cell lymphoma	0.005	0.995	0.000
C95 Leukaemia of unspecified cell type	0.005	0.995	0.000
C82.0 Small cleaved cell, follicular	0.005	0.995	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.005	0.995	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.005	0.995	0.000
C54.1 Endometrium	0.000	0.995	0.005
T43.0 Tricyclic and tetracyclic antidepressants	0.005	0.995	0.000
G72.0 Drug-induced myopathy	0.000	0.995	0.005
C82.3 Follicular lymphoma grade IIIa	0.005	0.995	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.000	0.995	0.005
T40.4 Other synthetic narcotics	0.005	0.995	0.000
C90.2 Plasmacytoma, extramedullary	0.005	0.995	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.005	0.995	0.000
C82.6 Cutaneous follicle centre lymphoma	0.005	0.995	0.000
C82.5 Diffuse follicle centre lymphoma	0.005	0.995	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.005	0.995	0.000
T40.2 Other opioids	0.005	0.995	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.005	0.995	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.005	0.995	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.005	0.995	0.000
C82.4 Follicular lymphoma grade IIIb	0.005	0.995	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.005	0.995	0.000
C91.7 Other lymphoid leukaemia	0.005	0.995	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.005	0.995	0.000
C91.3 Prolymphocytic leukaemia	0.005	0.995	0.000
C91.2 Subacute lymphocytic leukaemia	0.005	0.995	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.005	0.995	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.000	0.995	0.005
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.005	0.995	0.000
G72.1 Alcoholic myopathy	0.000	0.995	0.005
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.005	0.995	0.000
T40.5 Cocaine	0.005	0.995	0.000
G72.4 Inflammatory myopathy, not elsewhere classified	0.000	0.995	0.005
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.005	0.995	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.004	0.995	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.005	0.995	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.005	0.995	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.004	0.995	0.000
C85.0 Lymphosarcoma	0.004	0.995	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.004	0.995	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.004	0.995	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.004	0.995	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.004	0.995	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.004	0.995	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.004	0.995	0.000
T44.0 Anticholinesterase agents	0.004	0.995	0.000
C93.9 Monocytic leukaemia, unspecified	0.004	0.996	0.000
C93.7 Other monocytic leukaemia	0.004	0.996	0.000
C93.3 Juvenile myelomonocytic leukaemia	0.004	0.996	0.000
C93.2 Subacute monocytic leukaemia	0.004	0.996	0.000
C93.0 Acute monocytic leukaemia	0.004	0.996	0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.004	0.996	0.000
C96.8 Histiocytic sarcoma	0.004	0.996	0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.004	0.996	0.000
C96.6 Unifocal Langerhans-cell histiocytosis	0.004	0.996	0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.004	0.996	0.000
C96.4 Sarcoma of dendritic cells (accessory cells)	0.004	0.996	0.000
C96.3 True histiocytic lymphoma	0.004	0.996	0.000
C96.2 Malignant mast cell tumour	0.004	0.996	0.000
C96.1 Malignant histiocytosis	0.004	0.996	0.000
C96.0 Letterer-Siwe disease	0.004	0.996	0.000
C93.1 Chronic monocytic leukaemia	0.004	0.996	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.004	0.996	0.000
T40.8 Lysergide [LSD]	0.004	0.996	0.000
T40.7 Cannabis (derivatives)	0.004	0.996	0.000
T40.0 Opium	0.004	0.996	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.004	0.996	0.000
G72.3 Periodic paralysis	0.000	0.996	0.004
G72.2 Myopathy due to other toxic agents	0.000	0.996	0.004
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.004	0.996	0.000
T36 Poisoning by systemic antibiotics	0.004	0.996	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.004	0.996	0.000
T43.9 Psychotropic drug, unspecified	0.004	0.996	0.000
C94.7 Other specified leukaemias	0.004	0.996	0.000
C94.5 Acute myelofibrosis	0.004	0.996	0.000
C94.4 Acute panmyelosis	0.004	0.996	0.000
C94.3 Mast cell leukaemia	0.004	0.996	0.000
C94.2 Acute megakaryoblastic leukaemia	0.004	0.996	0.000
C94.1 Chronic erythraemia	0.004	0.996	0.000
C94.0 Acute erythraemia and erythroleukaemia	0.004	0.996	0.000
T40.1 Heroin	0.004	0.996	0.000
G72.8 Other specified myopathies	0.000	0.996	0.004
T43.6 Psychostimulants with abuse potential	0.004	0.996	0.000
T40.3 Methadone	0.004	0.996	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.000	0.996	0.004
C88 Malignant immunoproliferative diseases	0.004	0.996	0.000
M89.8 Other specified disorders of bone	0.000	0.996	0.004
T47.1 Other antacids and anti-gastric-secretion drugs	0.004	0.996	0.000
E53.8 Deficiency of other specified B group vitamins	0.004	0.996	0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.004	0.996	0.000
C86.4 Blastic NK-cell lymphoma	0.004	0.996	0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.004	0.996	0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.004	0.996	0.000
C86.1 Hepatosplenic T-cell lymphoma	0.004	0.996	0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.004	0.996	0.000
C91.9 Lymphoid leukaemia, unspecified	0.004	0.996	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.004	0.996	0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.000	0.996	0.004
C95.7 Other leukaemia of unspecified cell type	0.004	0.996	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.004	0.996	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.004	0.996	0.000
T38.5 Other oestrogens and progestogens	0.004	0.996	0.000
C91.5 Adult T-cell leukaemia	0.004	0.996	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.004	0.996	0.000
Z40 Prophylactic surgery	0.004	0.996	0.000
C82.2 Large cell, follicular	0.004	0.996	0.000
T38.1 Thyroid hormones and substitutes	0.004	0.996	0.000
C95.0 Acute leukaemia of unspecified cell type	0.004	0.996	0.000
C95.9 Leukaemia, unspecified	0.004	0.996	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.000	0.996	0.004
C82.1 Mixed small cleaved and large cell, follicular	0.004	0.996	0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.004	0.996	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.004	0.996	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.000	0.996	0.004
T38.0 Glucocorticoids and synthetic analogues	0.004	0.996	0.000
T36.4 Tetracyclines	0.004	0.996	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.004	0.996	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.004	0.996	0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.000	0.996	0.004
Z40.8 Other prophylactic surgery	0.004	0.996	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.004	0.996	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.004	0.996	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.004	0.996	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.003	0.996	0.000
T38.9 Other and unspecified hormone antagonists	0.004	0.996	0.000
T38.7 Androgens and anabolic congeners	0.004	0.996	0.000
T38.4 Oral contraceptives	0.004	0.996	0.000
T38.2 Antithyroid drugs	0.004	0.996	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.004	0.996	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.004	0.996	0.000
B97 Viral agents as the cause of diseases classified to other chapters	0.000	0.996	0.004
F33.9 Recurrent depressive disorder, unspecified	0.004	0.996	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.003	0.996	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.003	0.996	0.000
T37.5 Antiviral drugs	0.003	0.996	0.000
T37.4 Anthelminthics	0.003	0.996	0.000
T37.3 Other antiprotozoal drugs	0.003	0.996	0.000
T37.1 Antimycobacterial drugs	0.003	0.996	0.000
T37.0 Sulphonamides	0.003	0.996	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.003	0.996	0.000
T46.7 Peripheral vasodilators	0.003	0.996	0.000
L53.9 Erythematous condition, unspecified	0.000	0.996	0.004
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.003	0.996	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.003	0.997	0.000
M89.83 Other specified disorders of bone (Forearm)	0.000	0.997	0.003
T36.8 Other systemic antibiotics	0.003	0.997	0.000
T36.0 Penicillins	0.003	0.997	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.997	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
T36.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
T36.7 Antifungal antibiotics, systemically used	0.003	0.997	0.000
T36.6 Rifamycins	0.003	0.997	0.000
T36.5 Aminoglycosides	0.003	0.997	0.000
T36.2 Chloramphenicol group	0.003	0.997	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.003	0.997	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
T47.7 Emetics	0.003	0.997	0.000
T47.5 Digestants	0.003	0.997	0.000
T47.4 Other laxatives	0.003	0.997	0.000
T47.3 Saline and osmotic laxatives	0.003	0.997	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.003	0.997	0.000
T48.4 Expectorants	0.003	0.997	0.000
T48.3 Antitussives	0.003	0.997	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.003	0.997	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.003	0.997	0.000
T48.0 Oxytocic drugs	0.003	0.997	0.000
Z49.0 Preparatory care for dialysis	0.003	0.997	0.000
D07.1 Vulva	0.000	0.997	0.003
C90.3 Solitary plasmacytoma	0.003	0.997	0.000
T48.5 Anti-common-cold drugs	0.003	0.997	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.000	0.997	0.003
Z40.9 Prophylactic surgery, unspecified	0.003	0.997	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.000	0.997	0.003
M89.80 Other specified disorders of bone (Multiple sites)	0.000	0.997	0.003
C88.9 Malignant immunoproliferative disease, unspecified	0.003	0.997	0.000
C88.7 Other malignant immunoproliferative diseases	0.003	0.997	0.000
C88.3 Immunoproliferative small intestinal disease	0.003	0.997	0.000
C88.2 Gamma heavy chain disease	0.003	0.997	0.000
C88.1 Alpha heavy chain disease	0.003	0.997	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.000	0.997	0.003
T47.6 Antidiarrhoeal drugs	0.003	0.997	0.000
D07.4 Penis	0.000	0.997	0.003
T49.9 Topical agent, unspecified	0.003	0.997	0.000
T49.8 Other topical agents	0.003	0.997	0.000
T49.7 Dental drugs, topically applied	0.003	0.997	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.003	0.997	0.000
T49.5 Ophthalmological drugs and preparations	0.003	0.997	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.003	0.997	0.000
T49.3 Emollients, demulcents and protectants	0.003	0.997	0.000
T49.2 Local astringents and local detergents	0.003	0.997	0.000
T49.1 Antipruritics	0.003	0.997	0.000
T50.8 Diagnostic agents	0.003	0.997	0.000
E07.9 Disorder of thyroid, unspecified	0.003	0.997	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.003	0.997	0.000
C90.1 Plasma cell leukaemia	0.003	0.997	0.000
T41.5 Therapeutic gases	0.003	0.997	0.000
T41.4 Anaesthetic, unspecified	0.003	0.997	0.000
T41.3 Local anaesthetics	0.003	0.997	0.000
T41.1 Intravenous anaesthetics	0.003	0.997	0.000
T41.0 Inhaled anaesthetics	0.003	0.997	0.000
T47.2 Stimulant laxatives	0.003	0.997	0.000
X62.9 Unspecified place	0.003	0.997	0.000
D72.8 Other specified disorders of white blood cells	0.003	0.997	0.000
M89.84 Other specified disorders of bone (Hand)	0.000	0.997	0.003
T41.2 Other and unspecified general anaesthetics	0.003	0.997	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.003	0.997	0.000
T47.0 Histamine H(2)-receptor antagonists	0.003	0.997	0.000
D07.6 Other and unspecified male genital organs	0.000	0.997	0.003
D07.3 Other and unspecified female genital organs	0.000	0.997	0.003
T36.3 Macrolides	0.003	0.997	0.000
W25.9 Unspecified place	0.003	0.997	0.000
T46.1 Calcium-channel blockers	0.003	0.997	0.000
M89.88 Other specified disorders of bone (Other)	0.000	0.997	0.003
T46.4 Angiotensin-converting-enzyme inhibitors	0.003	0.997	0.000
C91.1 Chronic lymphocytic leukaemia	0.003	0.997	0.000
B97.6 Parvovirus as the cause of diseases classified to other chapters	0.000	0.997	0.003
B97.5 Reovirus as the cause of diseases classified to other chapters	0.000	0.997	0.003
B97.3 Retrovirus as the cause of diseases classified to other chapters	0.000	0.997	0.003
B97.2 Coronavirus as the cause of diseases classified to other chapters	0.000	0.997	0.003
B97.0 Adenovirus as the cause of diseases classified to other chapters	0.000	0.997	0.003
T50.6 Antidotes and chelating agents, not elsewhere classified	0.003	0.997	0.000
Z01.7 Laboratory examination	0.000	0.997	0.003
M25.71 Osteophyte (Shoulder region)	0.003	0.997	0.000
B97.1 Enterovirus as the cause of diseases classified to other chapters	0.000	0.997	0.003
C88.0 Waldenstrom's macroglobulinaemia	0.003	0.997	0.000
M25.74 Osteophyte (Hand)	0.003	0.997	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.003	0.997	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.003	0.997	0.000
D07.2 Vagina	0.000	0.997	0.003
D07.0 Endometrium	0.000	0.997	0.003
I34.0 Mitral (valve) insufficiency	0.000	0.997	0.003
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.000	0.997	0.003
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters	0.000	0.997	0.003
T50.7 Analeptics and opioid receptor antagonists	0.003	0.997	0.000
T50.5 Appetite depressants	0.003	0.997	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.003	0.997	0.000
T50.0 Mineralocorticoids and their antagonists	0.003	0.997	0.000
Z22.3 Carrier of other specified bacterial diseases	0.003	0.997	0.000
Z49.1 Extracorporeal dialysis	0.003	0.997	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.997	0.003
T50.4 Drugs affecting uric acid metabolism	0.003	0.997	0.000
T50.1 Loop [high-ceiling] diuretics	0.002	0.997	0.000
M25.77 Osteophyte (Ankle and foot)	0.003	0.997	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.003	0.997	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.003	0.997	0.000
R44.1 Visual hallucinations	0.003	0.997	0.000
C54 Malignant neoplasm of corpus uteri	0.000	0.997	0.003
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.002	0.997	0.001
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.000	0.997	0.003
M25.7 Osteophyte	0.003	0.997	0.000
R23.8 Other and unspecified skin changes	0.003	0.997	0.000
C85.1 B-cell lymphoma, unspecified	0.003	0.997	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.002	0.997	0.000
Z01.4 Gynaecological examination (general)(routine)	0.000	0.998	0.002
I71.0 Dissection of aorta [any part]	0.002	0.998	0.000
I97.1 Other functional disturbances following cardiac surgery	0.000	0.998	0.002
C81 Hodgkin's disease	0.002	0.998	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.002	0.998	0.000
E53 Deficiency of other B group vitamins	0.002	0.998	0.000
Z49 Care involving dialysis	0.002	0.998	0.000
M10.99 Gout, unspecified (Site unspecified)	0.002	0.998	0.000
Z01.0 Examination of eyes and vision	0.000	0.998	0.002
E05.0 Thyrotoxicosis with diffuse goitre	0.002	0.998	0.000
G55.2 Nerve root and plexus compressions in spondylosis	0.002	0.998	0.000
H02.3 Blepharochalasis	0.000	0.998	0.002
M25.79 Osteophyte (Site unspecified)	0.002	0.998	0.000
C45.0 Mesothelioma of pleura	0.000	0.998	0.002
T45.9 Primarily systemic and haematological agent, unspecified	0.002	0.998	0.000
T45.8 Other primarily systemic and haematological agents	0.002	0.998	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
T45.6 Fibrinolysis-affecting drugs	0.002	0.998	0.000
T45.3 Enzymes, not elsewhere classified	0.002	0.998	0.000
Z01.3 Examination of blood pressure	0.000	0.998	0.002
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.998	0.002
C43.5 Malignant melanoma of trunk	0.000	0.998	0.002
T45.4 Iron and its compounds	0.002	0.998	0.000
C54.8 Overlapping lesion of corpus uteri	0.000	0.998	0.002
C54.3 Fundus uteri	0.000	0.998	0.002
C54.2 Myometrium	0.000	0.998	0.002
C54.0 Isthmus uteri	0.000	0.998	0.002
T45.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
M25.70 Osteophyte (Multiple sites)	0.002	0.998	0.000
C71.9 Brain, unspecified	0.000	0.998	0.002
J32.8 Other chronic sinusitis	0.000	0.998	0.002
Z01.1 Examination of ears and hearing	0.000	0.998	0.002
Z01.9 Special examination, unspecified	0.000	0.998	0.002
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.002	0.998	0.000
R85.7 Abnormal histological findings	0.000	0.998	0.002
C54.9 Corpus uteri, unspecified	0.000	0.998	0.002
K82.8 Other specified diseases of gallbladder	0.000	0.998	0.002
G55.3 Nerve root and plexus compressions in other dorsopathies	0.002	0.998	0.000
F33 Recurrent depressive disorder	0.002	0.998	0.000
E53.9 Vitamin B deficiency, unspecified	0.002	0.998	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.998	0.002
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.002	0.998	0.000
C81.3 Lymphocytic depletion	0.002	0.998	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.002	0.998	0.000
M25.73 Osteophyte (Forearm)	0.002	0.998	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.000	0.998	0.002
S22.20 Fracture of sternum (closed)	0.000	0.998	0.002
E83.4 Disorders of magnesium metabolism	0.002	0.998	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.002	0.998	0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.002	0.998	0.000
E53.1 Pyridoxine deficiency	0.002	0.998	0.000
E53.0 Riboflavin deficiency	0.002	0.998	0.000
M25.78 Osteophyte (Other)	0.002	0.998	0.000
T45.5 Anticoagulants	0.002	0.998	0.000
T45.2 Vitamins, not elsewhere classified	0.002	0.998	0.000
Z01.6 Radiological examination, not elsewhere classified	0.000	0.998	0.002
Z01.5 Diagnostic skin and sensitisation tests	0.000	0.998	0.002
C81.0 Lymphocytic predominance	0.002	0.998	0.000
I86.1 Scrotal varices	0.000	0.998	0.002
C81.2 Mixed cellularity	0.001	0.998	0.000
R06.2 Wheezing	0.002	0.998	0.000
M87.2 Osteonecrosis due to previous trauma	0.002	0.998	0.000
E22 Hyperfunction of pituitary gland	0.000	0.998	0.002
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.002	0.998	0.000
Z32.0 Pregnancy, not (yet) confirmed	0.000	0.998	0.002
D03.3 Melanoma in situ of other and unspecified parts of face	0.000	0.998	0.002
E22.1 Hyperprolactinaemia	0.000	0.998	0.002
E22.0 Acromegaly and pituitary gigantism	0.000	0.998	0.002
J84.8 Other specified interstitial pulmonary diseases	0.002	0.998	0.000
K65.9 Peritonitis, unspecified	0.000	0.998	0.002
I97.0 Postcardiotomy syndrome	0.000	0.998	0.002
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.002	0.998	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.000	0.998	0.002
C81.7 Other Hodgkin's disease	0.001	0.998	0.001
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.998	0.002
M19.90 Arthrosis, unspecified (Multiple sites)	0.000	0.998	0.002
X63.0 Home	0.002	0.998	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.002	0.998	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.998	0.002
N70.1 Chronic salpingitis and oophoritis	0.000	0.998	0.002
T45.1 Antineoplastic and immunosuppressive drugs	0.001	0.998	0.000
M89.3 Hypertrophy of bone	0.000	0.998	0.002
Z01.2 Dental examination	0.000	0.998	0.001
C97 Malignant neoplasms of independent (primary) multiple sites	0.002	0.998	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.002	0.998	0.000
C45.9 Mesothelioma, unspecified	0.000	0.998	0.002
C81.1 Nodular sclerosis	0.001	0.998	0.000
M20.3 Other deformity of hallux (acquired)	0.002	0.998	0.000
T39.4 Antirheumatics, not elsewhere classified	0.002	0.998	0.000
T39.2 Pyrazolone derivatives	0.002	0.998	0.000
X62.0 Home	0.002	0.998	0.000
X62.7 Farm	0.002	0.998	0.000
X62.6 Industrial and construction area	0.002	0.998	0.000
X62.5 Trade and service area	0.002	0.998	0.000
X62.4 Street and highway	0.002	0.998	0.000
X62.3 Sports and athletics area	0.002	0.998	0.000
X62.2 School, other institution and public administrative area	0.002	0.998	0.000
X62.1 Residential institution	0.002	0.998	0.000
D72 Other disorders of white blood cells	0.002	0.998	0.000
J46 Status asthmaticus	0.000	0.998	0.002
M25.72 Osteophyte (Upper arm)	0.002	0.998	0.000
F33.8 Other recurrent depressive disorders	0.002	0.998	0.000
L05.0 Pilonidal cyst with abscess	0.002	0.998	0.000
L89.0 Stage I decubitus ulcer and pressure area	0.000	0.998	0.002
Z49.2 Other dialysis	0.002	0.998	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.002	0.998	0.000
M89.38 Hypertrophy of bone (Other)	0.000	0.998	0.002
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.002	0.998	0.000
M25.47 Effusion of joint (Ankle and foot)	0.002	0.998	0.000
X62.8 Other specified place	0.001	0.998	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.002	0.998	0.000
E05.9 Thyrotoxicosis, unspecified	0.002	0.998	0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.001	0.998	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.001	0.998	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.001	0.998	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.001	0.998	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.001	0.998	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.001	0.998	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.001	0.998	0.000
S52.80 Fracture of other parts of forearm (closed)	0.002	0.998	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.998	0.001
E22.8 Other hyperfunction of pituitary gland	0.000	0.998	0.001
N84.2 Polyp of vagina	0.002	0.998	0.000
C45 Mesothelioma	0.000	0.998	0.002
C45.7 Mesothelioma of other sites	0.000	0.998	0.002
T91.1 Sequelae of fracture of spine	0.000	0.998	0.002
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.001	0.998	0.000
O42.9 Premature rupture of membranes, unspecified	0.002	0.998	0.000
D72.1 Eosinophilia	0.001	0.998	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.001	0.998	0.000
N41.0 Acute prostatitis	0.000	0.998	0.002
J84 Other interstitial pulmonary diseases	0.002	0.998	0.000
M89 Other disorders of bone	0.000	0.998	0.001
M89.39 Hypertrophy of bone (Site unspecified)	0.000	0.998	0.001
M89.36 Hypertrophy of bone (Lower leg)	0.000	0.998	0.001
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.000	0.998	0.001
M89.34 Hypertrophy of bone (Hand)	0.000	0.998	0.001
M89.33 Hypertrophy of bone (Forearm)	0.000	0.998	0.001
M89.32 Hypertrophy of bone (Upper arm)	0.000	0.998	0.001
M89.31 Hypertrophy of bone (Shoulder region)	0.000	0.998	0.001
M89.30 Hypertrophy of bone (Multiple sites)	0.000	0.998	0.001
W25 Contact with sharp glass	0.001	0.998	0.000
M25.06 Haemarthrosis (Lower leg)	0.001	0.998	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.001	0.998	0.000
D72.9 Disorder of white blood cells, unspecified	0.001	0.998	0.000
D72.0 Genetic anomalies of leukocytes	0.001	0.998	0.000
X62.09 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified: Home: During unspecified activity	0.001	0.999	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.001	0.999	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.001	0.999	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.001	0.999	0.000
D16.3 Short bones of lower limb	0.000	0.999	0.001
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.001	0.999	0.000
M89.04 Algoneurodystrophy (Hand)	0.001	0.999	0.000
C45.2 Mesothelioma of pericardium	0.000	0.999	0.001
X10.0 Home	0.000	0.999	0.001
M25.52 Pain in joint (Upper arm)	0.000	0.999	0.001
M43.02 Spondylolysis (Cervical region)	0.001	0.999	0.000
F32.1 Moderate depressive episode	0.001	0.999	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.001	0.999	0.000
O36.5 Maternal care for poor foetal growth	0.000	0.999	0.001
X41.9 Unspecified place	0.001	0.999	0.000
M89.0 Algoneurodystrophy	0.001	0.999	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.001	0.999	0.000
M10.96 Gout, unspecified (Lower leg)	0.001	0.999	0.000
I07.1 Tricuspid insufficiency	0.001	0.999	0.000
K05.3 Chronic periodontitis	0.000	0.999	0.001
M90.10 Periostitis in other infectious diseases classified elsewhere (Multiple sites)	0.000	0.999	0.001
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.001	0.999	0.000
C45.1 Mesothelioma of peritoneum	0.000	0.999	0.001
I95.8 Other hypotension	0.000	0.999	0.001
J84.0 Alveolar and parietoalveolar conditions	0.001	0.999	0.000
M89.6 Osteopathy after poliomyelitis	0.000	0.999	0.001
M89.2 Other disorders of bone development and growth	0.000	0.999	0.001
M89.1 Epiphyseal arrest	0.000	0.999	0.001
E05 Thyrotoxicosis [hyperthyroidism]	0.001	0.999	0.000
L53 Other erythematous conditions	0.000	0.999	0.001
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.001	0.999	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.999	0.001
K26.3 Acute without haemorrhage or perforation	0.001	0.999	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.001	0.999	0.000
W25.6 Industrial and construction area	0.001	0.999	0.000
W25.5 Trade and service area	0.001	0.999	0.000
W25.1 Residential institution	0.001	0.999	0.000
W25.0 Home	0.001	0.999	0.000
W25.8 Other specified place	0.001	0.999	0.000
W25.7 Farm	0.001	0.999	0.000
W25.4 Street and highway	0.001	0.999	0.000
W25.3 Sports and athletics area	0.001	0.999	0.000
W25.2 School, other institution and public administrative area	0.001	0.999	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.001	0.999	0.000
Z99.2 Dependence on renal dialysis	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations